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Skin Cancer News
June 29, 2023

Top Headlines

Researchers Uncover Immune Cell Marker and Regulator of Anti-Tumor Immunity

B cells are thought to play a critical role in innate and adaptive immunity, but their exact role in anti-tumor immunity remains unknown. Researchers with expertise in immunology collaborated with experts in dermatology to further understand the role of B cells and identify a subset of cells that ...

基因工程细胞疗法开发目标Brain Metastatic Melanomas

Overall survival for patients with melanoma that has spread to the brain is only four to six months. Immunotherapies, which harness the power of the immune system to attack cancer cells, have garnered excitement in recent years for their potential to revolutionize the treatment of metastatic ...

Surprise Finding Shows That Neutrophils Can Be Key Antitumor Weapons

White blood cells called neutrophils have an unappreciated role in eradicating solid tumors, according to a surprise ...

Cancer Patients Who Don't Respond to Immunotherapy Lack Crucial Immune Cells

Cancer immunotherapy involves using activated T cells to destroy tumors, but it doesn't work for all patients. Researchers have discovered that a kind of dendritic cell is crucial for determining the effectiveness of immunotherapy. The discovery ...
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Latest Headlines
updated 2:58pm EDT

Earlier Headlines

Researchers Uncover Potential Biomarkers of Positive Response to Immunotherapy

Scientists have identified potential new biomarkers that could indicate how someone diagnosed with metastatic melanoma will respond to immunotherapy ...

Advanced Melanoma Survival Improves Significantly When Immunotherapy Is Given Before Targeted Therapy

A clinical trial showed a remarkable 20 percent advantage in the two-year overall survival rate for people with advanced melanoma who first received immunotherapy (72 percent survival rate) versus ...

Awakening 'Dormant' Cells to Fight Cancer

The advent of small-molecule targeted therapies, a decade ago, revolutionized the treatment of metastatic melanoma, provided that the tumors carry the mutations to respond to these treatments. ...

Tumors Form Temporary Structures to Avoid Immunotherapy Treatments

Scientists have shown how tumor cells evade immunotherapy by generating unique, temporary cell-in-cell structures, where the inner cells remain in tact and can return to single tumor ...

Researchers Decipher the Mechanism That Enables Skin Cancer to Metastasize to the Brain -- And Inhibited Its Spread by 80 Percent

Researchers have deciphered a mechanism that enables skin cancer to metastasize to the brain and managed to delay the spread of the disease by 60% to 80% using existing ...

Scientists Identify Key Biomarkers That Reliably Predict Response to Immune Checkpoint Inhibitor Therapy for Melanoma

Currently, the only FDA approved biomarker for ICI melanoma treatment is the tumor mutation burden assay, but the mechanisms linking it to ICI remain unclear. However, new research now provides ...

Melanoma Treatment: Potential Target Bypasses Therapeutic Resistance to Immune Checkpoint Blockers

Over the last decade, immune checkpoint blockers, or ICBs, have revolutionized treatment for various advanced cancers, including melanoma, the most aggressive skin cancer that was considered largely ...

Inhibiting Key Metabolic Enzyme Shows Promise Against Melanoma

Researchers have shown that inhibiting a key metabolic enzyme selectively kills melanoma cells and stops tumor growth. The findings could lead to a new class of drugs to selectively treat melanoma, ...

Identifying Melanoma Patients With High-Risk Disease

Medical researchers report on their identification of high-risk patients with stage 3A disease and microscopic lymph node metastases who would benefit from adjuvant ...

Targeted Cancer Vaccines Eliminate Tumors and Prevent Recurrence in Mice

Researchers developed a lipid nanoparticle-delivered cancer vaccine against a mouse model of melanoma that specifically targets the lymph system to generate greater potency. They were able to achieve ...

'RNA Fishing' Reveals New Driver of Melanoma Malignancy and Metastasis

Researchers have identified several proteins involved in the progression of melanoma. One of the proteins -- PDIA6 -- was found to be particularly important for driving malignancy. Experiments with ...

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Melanoma Thickness Equally Hard for Algorithms and Dermatologists to Judge

Assessing the thickness of melanoma is difficult, whether done by an experienced dermatologist or a well-trained machine-learning algorithm. A study shows that the algorithm and the dermatologists ...

New Insights Into Melanoma Brain Metastases

Cancer researchers have completed one of the most comprehensive studies of the cells inside melanoma brain ...

Researchers Discover DNA Copy Number Alterations Lead to Changes in RNA Circuits That Impact Melanoma Metastasis

Most cancer research and available anticancer drugs focus on the impact of DNA and protein alterations that contribute to cancer; however, it is now understood that RNA molecules can also both ...

Take the Burn out of Sunscreen Testing: Experts

Exposing humans to ultraviolet radiation to test sunscreen effectiveness should be phased out, according to scientists and cancer ...

Study Identifies Unique Underlying Molecular Factors Driving Melanoma Development

A new study reveals important molecular information that could help scientists develop more effective treatment and prevention strategies for a difficult-to-treat form of melanoma skin ...

Plant Virus Plus Immune Cell-Activating Antibody Clear Colon Cancer in Mice, Prevent Recurrence

A new combination therapy to combat cancer could one day consist of a plant virus and an antibody that activates the immune system's 'natural killer' cells, shows a new study. In mouse ...

Androgen Receptor Signaling Contributes to Targeted Therapy Resistance in Melanoma

Androgen receptor (AR) signaling affects response to BRAF/MEK inhibitor therapy in both males and females with melanoma, researchers have shown. The findings provide a new target to combat ...

Health: Higher Fish Consumption May Be Associated With Increased Melanoma Risk

Eating higher levels of fish, including tuna and non-fried fish, appears to be associated with a greater risk of malignant melanoma, suggests a large study of US ...

Nanotechnology Used to Destroy and Prevent Relapse of Solid Tumor Cancers

As people across the globe look forward to longer life expectancies, malignant cancers continue to pose threats to human health. The exploration and development of immunotherapy aims to seek new ...

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