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Cystic Fibrosis News
August 1, 2023

Top Headlines

Triple Combination Therapy Brings Lasting Improvement in Cystic Fibrosis

The mucus in the airways is not as sticky, inflammation in the lungs significantly reduced: Triple combination therapy can achieve these positive, lasting effects in patients with cystic fibrosis (CF). According to new research, this form of medication improves the symptoms of CF in many ...

Integrated Structural Biology Provides New Clues for Cystic Fibrosis Treatment

The cystic fibrosis transmembrane conductance regulator has been studied for years but the new efforts have yielded important ...

Cystic Fibrosis Drug Could Help Treat Pneumonia

病原体SARS-CoV-2和肺炎球菌等cause severe pneumonia. If the airways then fill with fluid, the patient risks developing acute respiratory distress syndrome. Researchers have now discovered the molecular mechanisms that trigger fluid accumulation in the lungs. This also led them ...

Cystic Fibrosis: Restoring Airway Integrity

Cystic fibrosis is a rare genetic disease which can cause very serious symptoms. In particular, patients suffer from chronic bacterial infections that can lead to respiratory failure. It is caused by mutations in the CFTR gene, which regulates water movement across the cell membrane. Consequently, ...
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Latest Headlines
updated 10:58pm EDT

Earlier Headlines

New Test Can Help Patients With Cystic Fibrosis

Researchers have developed a simple urine test to measure the severity of the serious disease cystic fibrosis and assess the effect of new ...

Non-White Newborns With Cystic Fibrosis More Likely to Be Missed in Screening

Cystic fibrosis is missed more often in newborn screenings for non-white than white babies, creating higher risk for irreversible lung damage and other serious outcomes in Black, Hispanic, Asian, ...

Cystic Fibrosis Patients Can Benefit from Vitamin Supplements, Research Shows

Cystic fibrosis patients who supplement their diet with vitamin C can also derive greater benefit from another antioxidant, vitamin E, resulting in a reduction in damaging inflammation, a study ...

Using iPSCs, Researchers Create Cells That Represent the Airways of Cystic Fibrosis Patients

Cystic fibrosis (CF) is caused by a mutation of the CFTR gene. While there are many hundreds of known mutations, not all of them are currently treatable which means a significant number of CF ...

Study Finds Delays in Initial Cystic Fibrosis Evaluation in Infants of Color

Infants from minoritized racial and ethnic backgrounds who have positive newborn screening tests for cystic fibrosis received their diagnostic follow-up for the disease later than recommended and ...

Lower Airways Are Distinct in Cystic Fibrosis Even at Younger Ages

In the largest study of its kind, researchers found that the lower airways in children with cystic fibrosis (CF) have a higher burden of infection, more inflammation and lower diversity of ...

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Bacterial Infections in Sinuses of Cystic Fibrosis Patients Share Surprising Similarities

A dogma-challenging discovery reveals that highly adapted bacterial communities in the sinuses of people with cystic fibrosis become more fragmented and experience mutations that erode their genomes. ...

New CRISPR/Cas9 Technique Corrects Cystic Fibrosis in Cultured Human Stem Cells

Researchers corrected mutations that cause cystic fibrosis in cultured human stem cells. They used a technique called prime editing to replace the 'faulty' piece of DNA with a healthy ...

A Small Molecule Induces Readthrough of Cystic Fibrosis CFTR Nonsense Mutations

An experimental drug suggests that a 'path is clearly achievable' to treat currently untreatable cases of cystic fibrosis disease caused by nonsense mutations. This includes about 11 ...

Scientists Demonstrate Promising New Approach for Treating Cystic Fibrosis

A new CF treatment strategy involves small, nucleic acid molecules called oligonucleotides that can correct some of the gene defects that underlie CF but are not addressed by existing modulator ...

Novel Nanotech Improves Cystic Fibrosis Antibiotic by 100,000-Fold, Research Shows

New nanotechnology could change the lives of thousands of people living with cystic fibrosis (CF) as groundbreaking research shows it can improve the effectiveness of the CF antibiotic Tobramycin, ...

Molecular Analysis Identifies Key Differences in Lungs of Cystic Fibrosis Patients

A team of researchers has developed a molecular catalog of cells in healthy lungs and the lungs of people with cystic ...

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Multi-Drug Resistant Infection About to Evolve Within Cystic Fibrosis Patients

Scientists have been able to track how a multi-drug resistant organism is able to evolve and spread widely among cystic fibrosis patients - showing that it can evolve rapidly within an individual ...

How Bacteria Defeat Drugs That Fight Cystic Fibrosis

Researchers and their partners have discovered a slimy strategy used by bacteria to defeat antibiotics and other drugs used to combat infections afflicting people with cystic ...

Scientists Reverse Deadly Impacts of Asthma in Mice

Excess mucus in the lungs can be fatal for asthma patients, but scientists have broken up those secretions at the molecular level and reversed their often deadly ...

Antifungal Drug Improves Key Cystic Fibrosis Biomarkers in Clinical Study

A drug widely used to treat fungal infections improved key biomarkers in lung tissue cultures as well as in the noses of patients with cystic fibrosis, a clinical study ...

Understanding Lung Infections in Patients With Cystic Fibrosis

年轻人与囊性纤维化、肺感染ion with Staphylococcus aureus, MRSA, is common and is treated with antibiotics in the hope that this will prevent a decline in lung function. ...

Genetic Mutation Could Worsen Heart Function in Duchenne Muscular Dystrophy Patients

基因的突变导致囊性纤维化may accelerate heart function decline in those with Duchenne muscular dystrophy (DMD), a new study suggests. The findings could help doctors develop ...

Mechanics of Mucus in Cystic Fibrosis Patients

New research examines the properties of the mucus of cystic fibrosis (CF) patients and the role it plays in a pathogens' ability to survive. The new information could have important implications ...

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