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Leukemia News
June 28, 2023

Top Headlines

Study Sets New Standard for Graft-Versus-Host Disease Prevention After Stem Cell Transplant

graft-versus-ho临床医生有一个新的标准st disease (GVHD) prevention after allogeneic hematopoietic stem cell transplantation, according to results from a phase III study. The new standard is more effective at preventing GVHD and came with ...

Further Hope for Base-Edited T-Cell Therapy to Treat Resistant Leukemia

Three young patients with relapsed T-cell leukemia have now been treated with base-edited ...

'Revolutionary' Research Discovers New Cause of Cancer Coming from Inside Us

Cancer researchers have made an important new connection between a person's cancer risk and the activity of circular RNAs, a poorly understood family of genetic fragments present in the body. A new study finds that specific circular RNAs within many ...

Drug Combination Restores Ability of Leading Treatment to Signal for Death of Blood Cancer Cells

Despite the promise of new medications that promote cancer cell death in people with acute myeloid leukemia, leukemic cells often adopt features that let them evade the drugs' effects within a ...
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Latest Headlines
updated 8:29am EDT

Earlier Headlines

Targeted Therapy Momelotinib Provides Significant Symptom and Anemia Improvements in Patients With Myelofibrosis

Patients with myelofibrosis had clinically significant improvement in disease-related symptoms, including anemia and spleen enlargement, when treated with the targeted therapy momelotinib, according ...

Inflammation Levels Tied to Severity of Blood Cancer

Severe inflammation weakens the body's ability to kill cancerous blood cells in people with acute myeloid leukemia (AML), a new study ...

Cancer: Blood Sample 24 Hours After Start of Chemotherapy Predicts Survival

Researchers have found a new method that within hours can predict if certain cancer patients will survive after ...

Pharmacotyping of Childhood Leukemia Provides a Blueprint for 'True Precision Medicine'

Scientists have performed the largest study yet examining drug sensitivity in childhood acute lymphoblastic leukemia across genomic subtypes and its association with treatment ...

Epigenetics Breaks Into the Clinical Practice of Cancer

Researchers describe the impact of epigenetics on cancer treatment and how it has become a crucial tool to improve early detection, predict disease progression and become a target for new ...

Enzyme Inhibition Promotes Bone Formation and Curbs the Development of Bone Metastases

In our bones, specialized cells called osteoblasts are responsible for building up bone substance. A team of researchers has now identified an enzyme that controls the activity of osteoblasts. An ...

Intestinal Microorganisms Influence White Blood Cell Levels in Blood

Intestinal bacteria composition is crucial to driving the recovery of neutrophils counts in the blood of mice following treatments such as stem cell transplants or ...

Miniature 'Bone Marrows in a Dish' to Improve Anti-Cancer Treatments

Scientists have made bone marrow 'organoids' that capture the key features of human bone ...

Researchers Pinpoint Potential Treatment for Lethal Childhood Cancer

Researchers discovered that by blocking the production of an enzyme called DHODH, they were able to halt the growth of MYC gene-amplified medulloblastoma in mouse models, the most aggressive subtype ...

Children With Resistant Leukemia Given CRISPR-Edited T Cells: Phase 1 Study Results Reported

Researchers have used CRISPR/Cas9 technology to engineer donor T cells to try to treat seriously ill children with resistant leukemia, who had otherwise exhausted all available ...

Spicing It Up: Pro-Drug Curcumin Shows Clinical Potential in Mice

A prodrug form of curcumin, TBP1901, has shown anti-tumor effects without toxicities. The enzyme GUSB was identified for its key role in TBP1901 conversion to curcumin, which also has essential ...

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Scientists Pinpoint Druggable Target in Aggressive Breast Cancer

Researchers have set their sights on a new therapeutic target for an aggressive form of breast cancer with limited treatment options. Through a comprehensive and cutting-edge genomic screening method ...

Corrupt Endothelial Cells Protect Blood Cancer Cells from Chemotherapy

Endothelial cells -- the cells that line blood vessels -- grown alongside leukemia cells become corrupted and rescue the cancer cells from many chemotherapy drugs, a study ...

Gene Signature Points to Prognosis in Kidney Cancer

Among patients with kidney cancer, the activity of four specific genes in the cancer cells seems to be able to predict the risk of the tumor spreading and the patient's chances of ...

High-Fat Diets Trigger Inflammatory Immune Cell Generation in Bone

Scientists have shown that high-fat diets can cause rapid changes in the bone marrow of mice, driving the production of inflammatory immune cells, according to new ...

To Wipe Childhood Cancer Off the Map, Scientists Must Chart Its Genomic Landscape

Scientists have created a roadmap of the genetic mutations present in the most common childhood cancer, acute lymphoblastic leukemia (ALL). The study supplies a comprehensive view of the genomics of ...

A New Kind of Chemo

Chemotherapy sucks. The treatments generally have awful side effects, and it's no secret that the drugs involved are often toxic to the patient as well as their cancer. The idea is that, since ...

Leukemia Vulnerability Discovered Causing Drug Sensitivity

All human tumors originating from various tissues share a series of properties that define them, including the ability to prevent cell death. Instead, healthy organs induce programmed cell death or ...

With Radically Improved Pain Control, Bone Marrow Donors Can Gift Stem Cells Without Worry of Undue Side Effects or Opioid Use

The potentially lifesaving act of gifting bone marrow can be accompanied by uncomfortable side effects to the donor, making it a truly selfless expression of kindness. Recognizing this good will and ...

Researchers Discover New Leukemia-Killing Compounds

Researchers have discovered potential new drugs that target mitochondria in cancer cells. Their study in the journal Leukemia describes the compounds' potential for killing leukemia cells when ...

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