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Dec. 3, 2020 —Xeno nucleic acids are essential for the development of nucleic acid-based drugs. To be effective, they need to be able to stably bind to natural RNA (a cellular single-stranded version of the DNA, ...
Nov. 30, 2020 —Antibiotics have revolutionized medicine by providing effective treatments for infectious diseases such as cholera. But the pathogens that cause disease are increasingly developing resistance to the ...
Dec. 15, 2021 —HIV replication in the human body requires that specific viral RNAs be packaged into progeny virus particles. A new study has found how a small difference in the RNA sequence can allow the viral RNA ...
Apr. 12, 2021 —Researchers have advanced a tumor-targeting and cell penetrating antibody that can deliver payloads to stimulate an immune response to help treat ...
Oct. 7, 2021 —Researchers have deciphered a molecular mechanism with which a small RNA and a small protein regulate the metabolism of cholera bacteria and the production of the cholera ...
June 2, 2021 —Scientists have detected Zika virus RNA in free-ranging African bats. RNA, or ribonucleic acid, is a molecule that plays a central role in the function of ...
Dec. 18, 2020 —Researchers have created a new polymer to deliver DNA and RNA-based therapies for diseases. For the first time in the industry, the researchers were able to see exactly how polymers interact with ...
Feb. 10, 2021 —A team of researchers has found a way to measure key characteristics of proteins that bind to RNA in cells--a discovery that could improve our understanding of how gene function is disturbed in ...
Mar. 30, 2022 —Until now, proteins have been the target of most medications for the prevention and treatment of human disease. Drug developers have perceived RNA to be too unstable to target with drug therapy. ...
Jan. 4, 2021 —Researchers have identified a molecular 'address' that explains how the cancer-related protein PRC2 binds to RNA to silence genes. The study resolves a longstanding debate about the ...