Colder, darker climates increase alcohol consumption and liver disease

The study, recently published online inHepatology, found that as temperature and sunlight hours dropped, alcohol consumption increased. Climate factors also were tied to binge drinking and the prevalence of alcoholic liver disease, one of the main causes of mortality in patients with prolonged excessive alcohol use.

"It's something that everyone has assumed for decades, but no one has scientifically demonstrated it. Why do people in Russia drink so much? Why in Wisconsin? Everybody assumes that's because it's cold," said senior author Ramon Bataller, M.D., Ph.D., chief of hepatology at UPMC, professor of medicine at Pitt, and associate director of the Pittsburgh Liver Research Center. "But we couldn't find a single paper linking climate to alcoholic intake or alcoholic cirrhosis. This is the first study that systematically demonstrates that worldwide and in America, in colder areas and areas with less sun, you have more drinking and more alcoholic cirrhosis."

酒精is a vasodilator -- it increases the flow of warm blood to the skin, which is full of temperature sensors -- so drinking can increase feelings of warmth. In Siberia that could be pleasant, but not so much in the Sahara.

Drinking also is linked to depression, which tends to be worse when sunlight is scarce and there's a chill in the air.

Using data from the World Health Organization, the World Meteorological Organization and other large, public data sets, Bataller's group found a clear negative correlation between climate factors -- average temperature and sunlight hours -- and alcohol consumption, measured as total alcohol intake per capita, percent of the population that drinks alcohol, and the incidence of binge drinking.

The researchers also found evidence that climate contributed to a higher burden of alcoholic liver disease. These trends were true both when comparing across countries around the world and also when comparing across counties within the United States.

"It's important to highlight the many confounding factors," said lead author Meritxell Ventura-Cots, Ph.D., a postdoctoral researcher at the Pittsburgh Liver Research Center. "We tried to control for as many as we could. For instance, we tried to control for religion and how that influences alcohol habits."

With much of the desert-dwelling Arab world abstaining from alcohol, it was critical to verify that the results would hold up even when excluding these Muslim-majority countries. Likewise, within the U.S., Utah has regulations that limit alcohol intake, which have to be taken into account.

When looking for patterns of cirrhosis, the researchers had to control for health factors that might exacerbate the effects of alcohol on the liver -- like viral hepatitis, obesity and smoking.

In addition to settling an age-old debate, this research suggests that policy initiatives aimed at reducing the burden of alcoholism and alcoholic liver disease should target geographic areas where alcohol is more likely to be problematic.