//www.koonmotors.com/news/plants_animals/rodents/ Rodents in scientific research. Read about rats, hamsters and mice. Learn about mouse allergens, beach mouse habitats, rodent control, lab mice, and the common house mouse. en-us Fri, 08 Sep 2023 22:52:15 EDT Fri, 08 Sep 2023 22:52:15 EDT 60 //www.koonmotors.com/images/scidaily-logo-rss.png//www.koonmotors.com/news/plants_animals/rodents/ For more science news, visit ScienceDaily. //www.koonmotors.com/releases/2023/08/230823165402.htm In a groundbreaking endeavor, researchers have successfully transferred a longevity gene from naked mole rats to mice, resulting in improved health and an extension of the mouse's lifespan. The research opens exciting possibilities for unlocking the secrets of aging and extending human lifespan. Wed, 23 Aug 2023 16:54:02 EDT //www.koonmotors.com/releases/2023/08/230823165402.htm //www.koonmotors.com/releases/2023/08/230811115448.htm Researchers have created a panel of genetically diverse mice that accurately model the highly variable human response to SARS-CoV-2 infection. The team uncovered differences in the innate immune and regulated proinflammatory responses, the timing and strength of which are associated with disease severity. Fri, 11 Aug 2023 11:54:48 EDT //www.koonmotors.com/releases/2023/08/230811115448.htm //www.koonmotors.com/releases/2023/08/230809125629.htm Researchers have created a functional 'humanized' liver in living mice that will help scientists find human-specific mechanisms for regulating cholesterol levels and potentially for treating chronic liver diseases afflicting tens of millions of people in the United States. Wed, 09 Aug 2023 12:56:29 EDT //www.koonmotors.com/releases/2023/08/230809125629.htm //www.koonmotors.com/releases/2023/07/230727144010.htm A process of surgically joining the circulatory systems of a young and old mouse slows the aging process at the cellular level and lengthens the lifespan of the older animal by up to 10%. Thu, 27 Jul 2023 14:40:10 EDT //www.koonmotors.com/releases/2023/07/230727144010.htm //www.koonmotors.com/releases/2023/07/230726171246.htm A team has discovered a protein that plays critical roles in alerting the body to a bacterial infection and initiating an effective immune response to fight back against the invasion. Wed, 26 Jul 2023 17:12:46 EDT //www.koonmotors.com/releases/2023/07/230726171246.htm //www.koonmotors.com/releases/2023/06/230620113815.htm Researchers have used an unprecedented stem cell zoo to compare six different mammalian species and their developmental time. Tue, 20 Jun 2023 11:38:15 EDT //www.koonmotors.com/releases/2023/06/230620113815.htm //www.koonmotors.com/releases/2023/06/230620113813.htm Some animals release chemical pheromones which can trigger behavioral or hormonal changes in other animals. It is known that calm rats can reduce the fear of nearby rats, but the exact mechanism was unknown. Researchers have found the pheromone responsible and demonstrated its effect both on lab rats and rats in the human environment. Their findings could lead to a new kind of humane pest control. Tue, 20 Jun 2023 11:38:13 EDT //www.koonmotors.com/releases/2023/06/230620113813.htm //www.koonmotors.com/releases/2023/05/230523185028.htm A non-toxic method to prevent mice from devouring wheat crops has been shown to drastically reduce seed loss. Tue, 23 May 2023 18:50:28 EDT //www.koonmotors.com/releases/2023/05/230523185028.htm //www.koonmotors.com/releases/2023/04/230406113950.htm People with Alzheimer's disease develop defects in cognitive functions like memory as well as problems with noncognitive functions that can lead to anxiety and depression. Investigators used mice to study a process through which new neurons are generated in adulthood, called adult hippocampus neurogenesis (AHN). The research showed that deep brain stimulation of new neurons helped restore both cognitive and noncognitive functions in mouse models of Alzheimer's disease. Thu, 06 Apr 2023 11:39:50 EDT //www.koonmotors.com/releases/2023/04/230406113950.htm //www.koonmotors.com/releases/2023/03/230324093449.htm MitoQ, a mitochondrial antioxidant that is available to the public as a diet supplement, was found in a mouse study to reverse the detrimental effects that HIV and antiretroviral therapy (ART) have on mitochondria in the brain, heart, aorta, lungs, kidney and liver. Fri, 24 Mar 2023 09:34:49 EDT //www.koonmotors.com/releases/2023/03/230324093449.htm //www.koonmotors.com/releases/2023/03/230314104023.htm Researchers compared a new genetic animal model of Down syndrome to the standard model and found the updated version to be enhanced. The new mouse model shows milder cognitive traits compared to a previously studied Down syndrome mouse model. Tue, 14 Mar 2023 10:40:23 EDT //www.koonmotors.com/releases/2023/03/230314104023.htm //www.koonmotors.com/releases/2023/02/230221113105.htm Unlike humans and other mammals, which become less fertile with age, naked mole-rats can reproduce throughout their remarkably long lifespans. A new study sheds light on unique processes that bestow the rodents with what seems like eternal fertility, findings that could eventually point to new therapies for people. Tue, 21 Feb 2023 11:31:05 EST //www.koonmotors.com/releases/2023/02/230221113105.htm //www.koonmotors.com/releases/2023/02/230202112654.htm Researchers show that brain organoids -- clumps of lab-grown neurons -- can integrate with rat brains and respond to visual stimulation like flashing lights. Thu, 02 Feb 2023 11:26:54 EST //www.koonmotors.com/releases/2023/02/230202112654.htm //www.koonmotors.com/releases/2023/01/230112155815.htm Research has identified the first inter-species signaling pathway between an arthropod parasite and host, where molecules in the blood of a host animal triggers the immunity and development of a parasite. The study showed that when ticks feed on the blood of mice infected with the bacteria Borrelia burgdorferi, which causes Lyme disease, a protein from the mouse immune system binds to receptors on tick cell surfaces and signals organs to develop more rapidly, producing an immune response long before the bacteria itself can begin to infect the tick. Thu, 12 Jan 2023 15:58:15 EST //www.koonmotors.com/releases/2023/01/230112155815.htm //www.koonmotors.com/releases/2023/01/230112113248.htm A team that has used two-photon imaging technology to show the creation and elimination of synapses between neurons in the brains of live mice. Thu, 12 Jan 2023 11:32:48 EST //www.koonmotors.com/releases/2023/01/230112113248.htm //www.koonmotors.com/releases/2023/01/230105151341.htm Scientists have discovered for the first time that invasive rats on tropical islands are affecting the territorial behavior of fish on surrounding coral reefs. The new study shows that the presence of invasive black rats on tropical islands is causing changes in the territorial behavior of the jewel damselfish -- a herbivorous species of tropical reef fish that 'farm' algae in the branches of corals. Thu, 05 Jan 2023 15:13:41 EST //www.koonmotors.com/releases/2023/01/230105151341.htm //www.koonmotors.com/releases/2022/12/221215161536.htm Mathematical modeling reveals how fleas with early-stage Yersinia pestis infections are insufficient to drive epizootic outbreaks but can help promote a low level of enzootic plague. Thu, 15 Dec 2022 16:15:36 EST //www.koonmotors.com/releases/2022/12/221215161536.htm //www.koonmotors.com/releases/2022/12/221213121546.htm In a global study, researchers have identified that most reservoirs of rodent-borne diseases tend to live exclusively or occasionally in or near human dwellings, show large fluctuations in their numbers, and/or are hunted for meat or fur. Tue, 13 Dec 2022 12:15:46 EST //www.koonmotors.com/releases/2022/12/221213121546.htm //www.koonmotors.com/releases/2022/12/221208114729.htm The first things that mouse newborns touch and eat establishes their native microbiome, which is often influenced by their mother during birth and throughout nursing. Although diet has been a known contributor to obesity in all stages of life, the effects of nursing mothers' diets is an ongoing investigation. Researchers find that when nursing mouse mothers are fed a low-fiber diet, their offspring's microbiome is permanently altered, leading to gut inflammation and obesity. Thu, 08 Dec 2022 11:47:29 EST //www.koonmotors.com/releases/2022/12/221208114729.htm //www.koonmotors.com/releases/2022/12/221202112519.htm A research team has discovered the underlying neural mechanism that allows us to feel empathy. The group's study on mice hinted that empathy is induced by the synchronized neural oscillations in the right hemisphere of the brain, which allows the animals to perceive and share each other's fear. Fri, 02 Dec 2022 11:25:19 EST //www.koonmotors.com/releases/2022/12/221202112519.htm //www.koonmotors.com/releases/2022/11/221128162125.htm The Sox9 gene is upregulated in the absence of sex-determining Y chromosome and Sry gene in Amami spiny rat. Mon, 28 Nov 2022 16:21:25 EST //www.koonmotors.com/releases/2022/11/221128162125.htm //www.koonmotors.com/releases/2022/11/221115184517.htm Researchers have assembled the first reference genome for the Nile rat -- a kind of genetic template of this species that may be used for laboratory and clinical studies. The hope is that it will be useful for those who investigate Type 2 diabetes and neurological disorders associated with a disrupted diurnal rhythm. The Nile rat is prone to diet-induced diabetes, and exhibits a clear diurnal pattern, unusual in rodents. Tue, 15 Nov 2022 18:45:17 EST //www.koonmotors.com/releases/2022/11/221115184517.htm //www.koonmotors.com/releases/2022/11/221114095300.htm A fluorescent protein makes it possible to follow disease progression in brain diseases such as Alzheimer's, strokes, and depression. That may lead to better insight into diseases and possible new treatments. Mon, 14 Nov 2022 09:53:00 EST //www.koonmotors.com/releases/2022/11/221114095300.htm //www.koonmotors.com/releases/2022/11/221111103007.htm Neuromedin U (NMU) is a hormone that suppresses appetite and affects energy metabolism and obesity patterns. Mice lacking NMU tend to become obese due to overeating, making NMU an ideal candidate for anti-obesity drugs. A group of scientists have investigated NMU does not affect functions related to food intake, energy metabolism, and obesity in rats by producing rats lacking NMU. The findings revealed species differences in NMU functions, entailing a more careful evaluation across species. Fri, 11 Nov 2022 10:30:07 EST //www.koonmotors.com/releases/2022/11/221111103007.htm //www.koonmotors.com/releases/2022/11/221104165402.htm The gene-silencing complex HUSH might be involved in complex disorders affecting the brain and neurons. However, its mechanism of action remains unclear. Researchers now uncover the in vivo targets and physiological functions of a component of the HUSH gene-silencing complex and one of its associated proteins. The work, conducted in laboratory mouse models and human brain organoids, links the HUSH complex to normal brain development, neuronal individuality and connectivity, as well as mouse behavior. Fri, 04 Nov 2022 16:54:02 EDT //www.koonmotors.com/releases/2022/11/221104165402.htm //www.koonmotors.com/releases/2022/10/221005111930.htm In the brain of adult mammals neural stem cells ensure that new nerve cells, i.e. neurons, are constantly formed. This process, known as adult neurogenesis, helps mice maintain their sense of smell. A research team recently discovered a second stem cell population in the mouse brain, which is primarily involved in the production of new neurons in the olfactory bulb of adult mice. Wed, 05 Oct 2022 11:19:30 EDT //www.koonmotors.com/releases/2022/10/221005111930.htm //www.koonmotors.com/releases/2022/10/221004134323.htm Researchers have identified a pathway in the brains of mice that is activated when the animals see other mice scratching and that, surprisingly, does not involve the brain's visual cortex. Tue, 04 Oct 2022 13:43:23 EDT //www.koonmotors.com/releases/2022/10/221004134323.htm //www.koonmotors.com/releases/2022/09/220928094758.htm Researchers have developed a Zika vaccine technology that is highly effective and safe in preclinical mouse models. Wed, 28 Sep 2022 09:47:58 EDT //www.koonmotors.com/releases/2022/09/220928094758.htm //www.koonmotors.com/releases/2022/09/220922103244.htm On an island 30 miles off the coast of San Francisco, a hoard of invasive house mice are packing an ecological wallop far larger than what their small statures would suggest. Thu, 22 Sep 2022 10:32:44 EDT //www.koonmotors.com/releases/2022/09/220922103244.htm //www.koonmotors.com/releases/2022/09/220914102006.htm In the 2001 'Amerithrax' attacks, anthrax-causing spores were sent through the mail to media outlets and members of Congress, sickening at least 22 people and killing five. Antibiotic-resistant strains of the bacteria are of growing concern, and researchers are preparing to fight back. Now, a team has taken a step toward the development of a therapeutic that can treat the infection in mice without antibiotics. Wed, 14 Sep 2022 10:20:06 EDT //www.koonmotors.com/releases/2022/09/220914102006.htm //www.koonmotors.com/releases/2022/09/220908131904.htm Researchers announce the development of a mouse embryo model, complete with beating hearts and the foundations for a brain and other organs, out of mouse embryonic stem cells. Thu, 08 Sep 2022 13:19:04 EDT //www.koonmotors.com/releases/2022/09/220908131904.htm //www.koonmotors.com/releases/2022/09/220907105446.htm An event that occurs only once every 120 years, the large-scale flowering, seeding, and dying of dwarf bamboo (Sasa borealis), has been found to provide ideal breeding conditions for Japanese field mice. Wed, 07 Sep 2022 10:54:46 EDT //www.koonmotors.com/releases/2022/09/220907105446.htm //www.koonmotors.com/releases/2022/08/220830093242.htm Researchers have developed the first mouse model for a mitochondrial tRNALeu mutation, showing that the associated metabolic disorder results from faulty RNA processing. Tue, 30 Aug 2022 09:32:42 EDT //www.koonmotors.com/releases/2022/08/220830093242.htm //www.koonmotors.com/releases/2022/08/220826113348.htm A review of decades of research revealed more than a dozen kinds of animals in addition to slugs and snails have caused rat lungworm disease in people around the world. Fri, 26 Aug 2022 11:33:48 EDT //www.koonmotors.com/releases/2022/08/220826113348.htm //www.koonmotors.com/releases/2022/08/220824103045.htm Researchers have found that gut bacteria in mice co-evolve with their hosts. Wed, 24 Aug 2022 10:30:45 EDT //www.koonmotors.com/releases/2022/08/220824103045.htm //www.koonmotors.com/releases/2022/08/220818141758.htm 菲律宾的山脉是密苏里州之一st biodiverse places on the planet. Inch for inch, these misty cloud forests are home to more unique species of mammals per square mile than anywhere else on Earth. Finding these mammals, most of which are tiny and hard to spot, is difficult work for even the most seasoned scientists. But the late biologist Danilo Balete had a special knack for field work. One of the mice he discovered has been revealed to be not just a new species, but a whole new genus. And preserving this mouse might be the key to saving endangered Philippine giant eagles that share its habitat. Thu, 18 Aug 2022 14:17:58 EDT //www.koonmotors.com/releases/2022/08/220818141758.htm //www.koonmotors.com/releases/2022/08/220804130600.htm 研究人员生成steri内老鼠的精子细胞le mice using a technique called blastocyst complementation. Thu, 04 Aug 2022 13:06:00 EDT //www.koonmotors.com/releases/2022/08/220804130600.htm //www.koonmotors.com/releases/2022/07/220728134111.htm Early exposure to antibiotics kills healthy bacteria in the digestive tract and can cause asthma and allergies, a new study demonstrates. Thu, 28 Jul 2022 13:41:11 EDT //www.koonmotors.com/releases/2022/07/220728134111.htm //www.koonmotors.com/releases/2022/07/220707141835.htm One often thinks that the early embryo is fragile and needs support. However, at the earliest stages of development, it has the power to feed the future placenta and instructs the uterus so that it can nest. Using 'blastoids', in vitro embryo models formed with stem cells, scientists have shown that the earliest molecular signals that induce placental development and prepare the uterus come from the embryo itself. Thu, 07 Jul 2022 14:18:35 EDT //www.koonmotors.com/releases/2022/07/220707141835.htm //www.koonmotors.com/releases/2022/07/220706085359.htm Scientists have developed a new technique for imaging mRNA molecules in the brains of living mice. The research reveals new insights into how memories are formed and stored in the brain and could allow scientists to learn more about diseases such as Alzheimer's in the future. Wed, 06 Jul 2022 08:53:59 EDT //www.koonmotors.com/releases/2022/07/220706085359.htm //www.koonmotors.com/releases/2022/07/220705162154.htm Researchers found that in mice how much they ate and when altered the nature of their gut microbiome: too much food too frequently resulted in poorer microbial and metabolic health. Tue, 05 Jul 2022 16:21:54 EDT //www.koonmotors.com/releases/2022/07/220705162154.htm //www.koonmotors.com/releases/2022/06/220629150322.htm A class of viruses known to cause severe diarrheal diseases -- including the one famous for widespread outbreaks on cruise ships -- can grow in the salivary glands of mice and spread through their saliva, scientists have discovered. The findings show that a new route of transmission exists for these common viruses, which afflict billions of people each year worldwide and can be deadly. Wed, 29 Jun 2022 15:03:22 EDT //www.koonmotors.com/releases/2022/06/220629150322.htm //www.koonmotors.com/releases/2022/06/220627141446.htm Researchers found mice were more likely to get infected by Omicron than other variants but with significantly lower mortality rates. Mon, 27 Jun 2022 14:14:46 EDT //www.koonmotors.com/releases/2022/06/220627141446.htm //www.koonmotors.com/releases/2022/06/220627100231.htm Researchers have discovered electrical brain-wave patterns given off during social interactions in mice. They also observed that mice showing signs of stress, depression, or autism lacked these brain waves. The results reveal more about the mechanics underlying brain activity when socializing. Mon, 27 Jun 2022 10:02:31 EDT //www.koonmotors.com/releases/2022/06/220627100231.htm //www.koonmotors.com/releases/2022/06/220623140518.htm Scientists map prominent differences in the neural circuits of mice, monkeys, and human. Thu, 23 Jun 2022 14:05:18 EDT //www.koonmotors.com/releases/2022/06/220623140518.htm //www.koonmotors.com/releases/2022/06/220614141553.htm 一项新的研究显示,阿片类药物镇痛芬太尼may induce autism-like behaviors in young male and female mice. The findings indicate that reduced expression of the gene Grin2b in the anterior cingulate cortex of the brain following fentanyl treatment accounts for the autism-like behavior in the mice. However, there is no current evidence that fentanyl is associated with a similar effect in humans. The outcomes of the animal study are not an indication to avoid fentanyl in clinical use. Tue, 14 Jun 2022 14:15:53 EDT //www.koonmotors.com/releases/2022/06/220614141553.htm //www.koonmotors.com/releases/2022/06/220614095611.htm Scientists have revealed the genetic structure and diversity, and inferred the population history, of the wild house mouse across Europe and Asia. Tue, 14 Jun 2022 09:56:11 EDT //www.koonmotors.com/releases/2022/06/220614095611.htm //www.koonmotors.com/releases/2022/06/220606145410.htm Biomedical and genetic engineers have developed a process to change the color of a mouse's tissue to better image its internal physiology. The approach will help researchers isolate and remove sources of strong background noise in biomedical images, giving them unprecedented access to observe, influence and image biological processes with a swiftly developing imaging technique called photoacoustic imaging. Mon, 06 Jun 2022 14:54:10 EDT //www.koonmotors.com/releases/2022/06/220606145410.htm //www.koonmotors.com/releases/2022/05/220525110841.htm Escaping imminent danger is essential for survival. Animals must learn a new environment fast enough for them to be able to choose the shortest route to safety. But how do they do this without ever having experienced threat in the new environment? Wed, 25 May 2022 11:08:41 EDT //www.koonmotors.com/releases/2022/05/220525110841.htm //www.koonmotors.com/releases/2022/05/220516104643.htm 新的基因编辑技术揭示how hormones impact social behavior in animals and possibly, humans. 2022年5月16日星期一10:46:43 EDT //www.koonmotors.com/releases/2022/05/220516104643.htm //www.koonmotors.com/releases/2022/05/220511142354.htm Researchers have shown for the first time in mice that heart problems associated with the flu are not caused by raging inflammation in the lungs, as has long been predicted. Instead, the electrical malfunctions and heart scarring seen in some of the sickest flu patients are caused by direct influenza infection of cardiac cells. Wed, 11 May 2022 14:23:54 EDT //www.koonmotors.com/releases/2022/05/220511142354.htm //www.koonmotors.com/releases/2022/05/220511123548.htm A team of scientists is making inroads in understanding the relationship between certain enzymes that are normally produced in the body and their role in regulating obesity and controlling liver diseases. Researchers studied male mice that lacked the Cyp2b enzyme and how the lack of the enzyme affected the mice's metabolism. Wed, 11 May 2022 12:35:48 EDT //www.koonmotors.com/releases/2022/05/220511123548.htm //www.koonmotors.com/releases/2022/05/220503141339.htm New ancient DNA analysis has shed light on how the black rat, blamed for spreading Black Death, dispersed across Europe -- revealing that the rodent colonized the continent on two occasions in the Roman and Medieval periods. By analyzing DNA from ancient black rat remains found at archaeological sites spanning the 1st to the 17th centuries in Europe and North Africa, researchers have pieced together a new understanding of how rat populations dispersed following the ebbs and flows of human trade, urbanism, and empires. Tue, 03 May 2022 14:13:39 EDT //www.koonmotors.com/releases/2022/05/220503141339.htm //www.koonmotors.com/releases/2022/04/220428103943.htm Biomedical engineers have developed an artificial intelligence (AI) training strategy to capture images of mouse brain cells in action. The researchers say the AI system, in concert with specialized ultra-small microscopes, make it possible to find precisely where and when cells are activated during movement, learning and memory. Thu, 28 Apr 2022 10:39:43 EDT //www.koonmotors.com/releases/2022/04/220428103943.htm //www.koonmotors.com/releases/2022/03/220315112951.htm The difference between a social butterfly and a lone wolf is actually at least eight differences, according to new findings by a team of brain researchers. By simultaneously spying on the electrical activity of several brain regions, researchers can both identify how social or solitary an individual mouse is, and, by zapping nodes within this social brain network, can prompt mice to be even more gregarious. Tue, 15 Mar 2022 11:29:51 EDT //www.koonmotors.com/releases/2022/03/220315112951.htm //www.koonmotors.com/releases/2022/03/220314105609.htm In pursuit of better ways to test new therapies and further explore the impacts of the unique genetics associated with Down syndrome, researchers have genetically engineered and characterized what is believed to be the first rat model of Down syndrome. Mon, 14 Mar 2022 10:56:09 EDT //www.koonmotors.com/releases/2022/03/220314105609.htm //www.koonmotors.com/releases/2022/03/220311141432.htm Briefly blocking a key molecule when administering the only approved vaccine for tuberculosis vastly improves long-term protection against the devastating disease in mice, researchers report. Fri, 11 Mar 2022 14:14:32 EST //www.koonmotors.com/releases/2022/03/220311141432.htm //www.koonmotors.com/releases/2022/03/220309111050.htm Dinosaurs went extinct 65 million years ago, mammoths 4,000 years ago, and the Christmas Island Rat 119 years ago. Since becoming a popular concept in the 1990s, de-extinction efforts have focused on grand animals with mythical stature, but now a team of paleogeneticists has turned their attention to Rattus macleari, and their findings provide insights into the limitations of de-extinction across all species. Wed, 09 Mar 2022 11:10:50 EST //www.koonmotors.com/releases/2022/03/220309111050.htm //www.koonmotors.com/releases/2022/03/220304112016.htm Mice that received treatments with peanut-coated microneedles had significant increased rates of desensitization to peanut allergy compared with epicutaneous immunotherapy (EPIT), a new study found. The microneedle treatment success was achieved despite applying a dose of peanut protein 10-times lower than the dose delivered by EPIT. Researchers say the findings demonstrate the potential for peanut microneedles to improve food allergen immunotherapy through the skin. Fri, 04 Mar 2022 11:20:16 EST //www.koonmotors.com/releases/2022/03/220304112016.htm //www.koonmotors.com/releases/2022/02/220228114422.htm Researchers have developed a technology, heteroduplex oligonucleotide (HDO), that silences certain genes whose high expression levels fuel disease. Adding a specific molecular tag allowed them to target the HDO to immune cells called lymphocytes safely and efficiently. Doing so with an HDO specific to a gene called Itga4 improved symptoms in a mouse model of multiple sclerosis, suggesting this technology may be developed to use in human immune disorders. 星期一,2022年2月28日11:44:22 EST //www.koonmotors.com/releases/2022/02/220228114422.htm