Mice News -- ScienceDaily //www.koonmotors.com/news/plants_animals/mice/ The mouse. What have researchers learned from obese mice, anxious mice and cancer-resistant mice? Read research using mouse models of disease. en-us Fri, 08 Sep 2023 12:23:15 EDT Fri, 08 Sep 2023 12:23:15 EDT 60 Mice News -- ScienceDaily //www.koonmotors.com/images/scidaily-logo-rss.png//www.koonmotors.com/news/plants_animals/mice/ For more science news, visit ScienceDaily. Fiber from crustaceans, insects, mushrooms promotes digestion //www.koonmotors.com/releases/2023/09/230907141931.htm Crustaceans, insects and mushrooms are rich sources of the dietary fiber chitin, which activates the immune system and benefits metabolism, according to a new study in mice. Thu, 07 Sep 2023 14:19:31 EDT //www.koonmotors.com/releases/2023/09/230907141931.htm Researchers grow embryonic humanized kidneys inside pigs for 28 days //www.koonmotors.com/releases/2023/09/230907130350.htm Researchers have successfully created chimeric embryos containing a combination of human and pig cells. When transferred into surrogate pig mothers, the developing humanized kidneys had normal structure and tubule formation after 28 days. This is the first time that scientists have been able to grow a solid humanized organ inside another species, though previous studies have used similar methods to generate human tissues such as blood or skeletal muscle in pigs. Thu, 07 Sep 2023 13:03:50 EDT //www.koonmotors.com/releases/2023/09/230907130350.htm Blood-brain barrier governs ant behavior by altering hormone levels //www.koonmotors.com/releases/2023/09/230907130345.htm In many animals, including ants, the blood-brain barrier (BBB) ensures normal brain function by controlling the movement of various substances in and out of the brain. Now, researchers have made the unexpected discovery that the BBB in carpenter ants plays an active role in controlling behavior that's essential to the function of entire ant colonies. The key is production in the BBB of a particular hormone-degrading enzyme. Thu, 07 Sep 2023 13:03:45 EDT //www.koonmotors.com/releases/2023/09/230907130345.htm Discovery of new cell type in thymus //www.koonmotors.com/releases/2023/09/230906115617.htm Biomedical scientists have confirmed that newly discovered cells in the thymus are just like M cells, which are mostly known for their presence in the intestinal epithelium. Wed, 06 Sep 2023 11:56:17 EDT //www.koonmotors.com/releases/2023/09/230906115617.htm Resistant starch supplement reduces liver triglycerides in people with fatty liver disease //www.koonmotors.com/releases/2023/09/230905124907.htm Resistant starch is a nondigestible fiber that ferments in the large intestine, and consumption of it has previously been shown to have a positive effect on metabolism in animal studies. Now, a 4-month randomized controlled trial in people with non-alcoholic fatty liver disease (NAFLD) indicates that daily intake of resistant starch can alter gut bacteria composition and lower liver triglycerides and liver enzymes associated with liver injury and inflammation. Tue, 05 Sep 2023 12:49:07 EDT //www.koonmotors.com/releases/2023/09/230905124907.htm Di-isononyl phthalate disrupts pregnancy in mice, study finds //www.koonmotors.com/releases/2023/09/230901124051.htm In a new study, researchers used mice to understand how DiNP affects pregnancy. Fri, 01 Sep 2023 12:40:51 EDT //www.koonmotors.com/releases/2023/09/230901124051.htm Red blood cells exposed to oxygen deficiency protect against myocardial infarction //www.koonmotors.com/releases/2023/09/230901124039.htm Red blood cells exposed to oxygen deficiency protect against myocardial infarction, according to a new study. The study also shows that the protective effect is enhanced by a nitrate-rich vegetable diet. Fri, 01 Sep 2023 12:40:39 EDT //www.koonmotors.com/releases/2023/09/230901124039.htm Digging deeper into how vaccines work against parasitic disease //www.koonmotors.com/releases/2023/08/230831164439.htm Researchers have determined how Leishmaniasis vaccine candidates, created using mutated disease-causing parasites, prompt molecular-level changes in host cells that have specific roles in helping generate the immune response. Thu, 31 Aug 2023 16:44:39 EDT //www.koonmotors.com/releases/2023/08/230831164439.htm A new breakthrough in obesity research may allow you to lose fat while eating all you want //www.koonmotors.com/releases/2023/08/230831121624.htm This is a significant development that brings hope to the one billion individuals with obesity worldwide. Researchers have discovered new insights into the regulation of fat metabolism. The focus of their study lies within the star-shaped non-neuronal cells in the brain, known as 'astrocytes'. Furthermore, the group announced successful animal experiments using the newly developed drug 'KDS2010', which allowed the mice to lose weigh without dietary restrictions. Thu, 31 Aug 2023 12:16:24 EDT //www.koonmotors.com/releases/2023/08/230831121624.htm Inhalable molecules neutralize SARS-CoV-2 in mice, study finds //www.koonmotors.com/releases/2023/08/230830131708.htm Nanofitins, which are derived from a protein in an archaeal microorganism found in hot springs -- successfully neutralized SARS-CoV-2 in mice and were well-tolerated. When inhaled by the rodents, the engineered nanofitins, which inhibit the virus by binding to its spike proteins, were observed to quickly reach the lungs in high doses both preventing and clearing early infections, researchers report. Wed, 30 Aug 2023 13:17:08 EDT //www.koonmotors.com/releases/2023/08/230830131708.htm Bacteria treatment reduces insulin resistance, protects against diabetes //www.koonmotors.com/releases/2023/08/230830131655.htm Researchers have discovered a type of gut bacteria that might help improve insulin resistance, and thus protect against the development of obesity and type-2 diabetes. The study involved genetic and metabolic analysis of human fecal microbiomes and then corroborating experiments in obese mice. Wed, 30 Aug 2023 13:16:55 EDT //www.koonmotors.com/releases/2023/08/230830131655.htm Yeast studies show that diet in early life matters for lifelong health //www.koonmotors.com/releases/2023/08/230829141649.htm Researchers have shown that the content of diet in yeast, rather than caloric intake, influences yeast health in later stages of their lifecycle. The different diet placed cells on a path to age healthily and avoid aging pathologies, though they did not live longer. Tue, 29 Aug 2023 14:16:49 EDT //www.koonmotors.com/releases/2023/08/230829141649.htm Enhancing cancer therapy using functionalized photosynthetic bacteria //www.koonmotors.com/releases/2023/08/230829125956.htm Selective targeting of cancerous cells poses major clinical challenges during cancer therapy. However, this limitation can be overcome by using bioengineered bacteria with highly optimized chemical modifications. A recent study demonstrates the use of chemically modified purple photosynthetic bacteria for the successful detection and elimination of colon cancer cells in a mouse model. The study also sheds light on the underlying mechanism of action. Tue, 29 Aug 2023 12:59:56 EDT //www.koonmotors.com/releases/2023/08/230829125956.htm Unlocking the secrets of cell antennas //www.koonmotors.com/releases/2023/08/230825140357.htm NSL(非特异性致命)复杂的调节thousands of genes in fruit flies and mammals. Silencing the NSL genes leads to the death of the organism, which gave the complex its curious name. Researchers have now discovered that the genes regulated by the NSL complex also include genes of the intraciliary transport system. This enables different cell types to form cilia on their surface, which are important for cell communication. The study shows that these genes are 'switched on' by the NSL complex, regardless of whether a particular cell has cilia or not. The researchers found that this class of cilia-associated genes is crucial for the function of podocytes. This is a highly specialized cell type of the kidney that, paradoxically, does not have cilia. These findings have important implications for ciliopathies and kidney disease. Fri, 25 Aug 2023 14:03:57 EDT //www.koonmotors.com/releases/2023/08/230825140357.htm Epigenetic mechanism that causes bitter taste distortion discovered //www.koonmotors.com/releases/2023/08/230824120153.htm A bitter taste in the mouth is often a symptom or side effect of illness, which may be the result of how the body reacts to pathogens. A new study sheds light on the mechanisms involved in the complex interplay between taste perception and immune function. Their work also highlights the potential of a sequencing tool for investigating epigenetic mechanisms that affect taste-cell gene expression. Thu, 24 Aug 2023 12:01:53 EDT //www.koonmotors.com/releases/2023/08/230824120153.htm Researchers describe rebuilding, regenerating lung cells //www.koonmotors.com/releases/2023/08/230824111925.htm Researchers have discovered a novel approach for engrafting engineered cells into injured lung tissue. These findings may lead to new ways for treating lung diseases, such as emphysema, pulmonary fibrosis and COVID-19. The two studies describe the methodologies for engineering lung stem cells and transplanting them into injured experimental lungs without immunosuppression. Thu, 24 Aug 2023 11:19:25 EDT //www.koonmotors.com/releases/2023/08/230824111925.htm Longevity gene from naked mole rats extends lifespan of mice //www.koonmotors.com/releases/2023/08/230823165402.htm In a groundbreaking endeavor, researchers have successfully transferred a longevity gene from naked mole rats to mice, resulting in improved health and an extension of the mouse's lifespan. The research opens exciting possibilities for unlocking the secrets of aging and extending human lifespan. Wed, 23 Aug 2023 16:54:02 EDT //www.koonmotors.com/releases/2023/08/230823165402.htm High-fat diets alter gut bacteria, boosting colorectal cancer risk in mice //www.koonmotors.com/releases/2023/08/230822111728.htm Researchers have discovered how high-fat diets can change gut bacteria and alter digestive molecules called bile acids that are modified by those bacteria, predisposing mice to colorectal cancer. The findings bring scientists closer to understanding the causes of and how to prevent colorectal cancer. Tue, 22 Aug 2023 11:17:28 EDT //www.koonmotors.com/releases/2023/08/230822111728.htm Molecules in vegetables can help to ease lung infection //www.koonmotors.com/releases/2023/08/230816114227.htm Researchers have found that molecules in vegetables like broccoli or cauliflower help to maintain a healthy barrier in the lung and ease infection. Wed, 16 Aug 2023 11:42:27 EDT //www.koonmotors.com/releases/2023/08/230816114227.htm Microgreens and mature veggies differ in nutrients, but both might limit weight gain //www.koonmotors.com/releases/2023/08/230816114209.htm Young vegetables known as microgreens are reputed to be particularly good for health. But are microgreens the superfood they're claimed to be, and how do they compare to mature veggies? Scientists have found that their nutritional profiles differ, as do their effects on gut bacteria. Yet, tests in mice suggest that both microgreen and mature vegetables can limit weight gain. Wed, 16 Aug 2023 11:42:09 EDT //www.koonmotors.com/releases/2023/08/230816114209.htm Certain sugars affect brain 'plasticity,' helping with learning, memory, recovery //www.koonmotors.com/releases/2023/08/230816114207.htm Can you recognize an old friend, but forget what you had for breakfast yesterday? Our brains constantly rearrange their circuitry to retain information, but the molecular basis behind this process isn't well understood. New research suggests that complex sugars called glycosaminoglycans might play a major role in the 'plasticity' of the brains of mice and could be used to repair neural connections after injury. Wed, 16 Aug 2023 11:42:07 EDT //www.koonmotors.com/releases/2023/08/230816114207.htm Building muscle in the lab //www.koonmotors.com/releases/2023/08/230816114121.htm A new method allows large quantities of muscle stem cells to be safely obtained in cell culture. This provides a potential for treating patients with muscle diseases -- and for those who would like to eat meat, but don't want to kill animals. Wed, 16 Aug 2023 11:41:21 EDT //www.koonmotors.com/releases/2023/08/230816114121.htm Scientists discover external protein network can help stabilize neural connections //www.koonmotors.com/releases/2023/08/230816114059.htm The Noelin family of secreted proteins bind to the external portion of AMPA glutamate receptors and stabilize them on the neuronal cellular membrane, a process necessary for transmission of full-strength signals between neurons, according to a new study. Wed, 16 Aug 2023 11:40:59 EDT //www.koonmotors.com/releases/2023/08/230816114059.htm Oxygen charge for battling multidrug-resistant pathogens //www.koonmotors.com/releases/2023/08/230816113637.htm In antibacterial photodynamic therapy, irradiation is used to produce reactive oxygen species that kill off bacteria. Because it requires external light and oxygen, this method is only suitable for surface infections. A research team has now introduced a molecular 'singlet oxygen battery' that can be 'charged' with reactive oxygen, which it then releases in deep tissue layers to target methicillin-resistant staphylococcus. Wed, 16 Aug 2023 11:36:37 EDT //www.koonmotors.com/releases/2023/08/230816113637.htm Variable patient responses to SARS-CoV-2 infection are mimicked in genetically diverse mice //www.koonmotors.com/releases/2023/08/230811115448.htm 研究人员创建了一个组基因diverse mice that accurately model the highly variable human response to SARS-CoV-2 infection. The team uncovered differences in the innate immune and regulated proinflammatory responses, the timing and strength of which are associated with disease severity. Fri, 11 Aug 2023 11:54:48 EDT //www.koonmotors.com/releases/2023/08/230811115448.htm Global consortium creates large-scale, cross-species database and universal 'clock' to estimate age in all mammalian tissues //www.koonmotors.com/releases/2023/08/230810141041.htm An international research team details changes in DNA that researchers found are shared by humans and other mammals throughout history and are associated with life span and numerous other traits. Thu, 10 Aug 2023 14:10:41 EDT //www.koonmotors.com/releases/2023/08/230810141041.htm Researchers engineer bacteria that can detect tumor DNA //www.koonmotors.com/releases/2023/08/230810140813.htm Creating new technologically advanced sensors, scientists have engineered bacteria that detect the presence of tumor DNA in live organisms. Their innovation could pave the way to new biosensors capable of identifying various infections, cancers and other diseases. 星期四,2023年8月10日美国东部时间14:08:13 //www.koonmotors.com/releases/2023/08/230810140813.htm Gut microbiome can increase risk, severity of HIV, EBV disease //www.koonmotors.com/releases/2023/08/230810110414.htm Researchers created a germ-free mouse model to evaluate the role of the microbiome in the infection, replication, and pathogenesis of HIV and the Epstein-Barr virus, the virus that can cause mononucleosis and other serious diseases. Thu, 10 Aug 2023 11:04:14 EDT //www.koonmotors.com/releases/2023/08/230810110414.htm Scientists reverse hearing loss in mice //www.koonmotors.com/releases/2023/08/230810110338.htm New research has successfully reversed hearing loss in mice. Scientists used a genetic approach to fix deafness in mice, restoring their hearing abilities in low and middle frequency ranges. Thu, 10 Aug 2023 11:03:38 EDT //www.koonmotors.com/releases/2023/08/230810110338.htm A therapeutic target for Alzheimer's disease discovered //www.koonmotors.com/releases/2023/08/230810110325.htm Scientists have succeeded in reversing certain cognitive manifestations associated with Alzheimer's disease in an animal model of the disease. Thu, 10 Aug 2023 11:03:25 EDT //www.koonmotors.com/releases/2023/08/230810110325.htm Sugars in breastmilk could help treat infections, prevent preterm births //www.koonmotors.com/releases/2023/08/230809130643.htm Breastfeeding has long been used as a method to help keep newborns healthy and protected against a variety of diseases. But certain sugars naturally found in breastmilk could also help prevent infections before a baby arrives. Researchers have found that these sugars can stop a common prenatal infection in human tissues and pregnant mice. This could someday help people avoid preterm births or complications without the need for additional antibiotics. Wed, 09 Aug 2023 13:06:43 EDT //www.koonmotors.com/releases/2023/08/230809130643.htm 'Humanized' liver in mice reveals roots of chronic diseases //www.koonmotors.com/releases/2023/08/230809125629.htm Researchers have created a functional 'humanized' liver in living mice that will help scientists find human-specific mechanisms for regulating cholesterol levels and potentially for treating chronic liver diseases afflicting tens of millions of people in the United States. Wed, 09 Aug 2023 12:56:29 EDT //www.koonmotors.com/releases/2023/08/230809125629.htm Tropical plant native to China reveals antiobesity potential //www.koonmotors.com/releases/2023/08/230804123740.htm Scientists tested the antiobesity effects of Mallotus furetianus extract native to Hainan Island, China, using obesity model mice. As a result, body weight and adipose tissue weight of obesity model mice were significantly reduced by the intake of Mallotus furetianus extract. Fatty liver was suppressed and adipocyte size reduction in adipose tissue was observed. Further investigation into the mechanism revealed that fat synthesis is inhibited by suppressing the expression of several transcription factors involved in differentiation into adipocytes. Fri, 04 Aug 2023 12:37:40 EDT //www.koonmotors.com/releases/2023/08/230804123740.htm How the gut signals to the brain //www.koonmotors.com/releases/2023/08/230803113020.htm Scientists define five types of colon neurons specialized for sending different signals to the brain. Thu, 03 Aug 2023 11:30:20 EDT //www.koonmotors.com/releases/2023/08/230803113020.htm Aging process slows when older mice share circulatory system of young //www.koonmotors.com/releases/2023/07/230727144010.htm A process of surgically joining the circulatory systems of a young and old mouse slows the aging process at the cellular level and lengthens the lifespan of the older animal by up to 10%. Thu, 27 Jul 2023 14:40:10 EDT //www.koonmotors.com/releases/2023/07/230727144010.htm Scientist discover protein required for an effective immune response to invading bacteria //www.koonmotors.com/releases/2023/07/230726171246.htm A team has discovered a protein that plays critical roles in alerting the body to a bacterial infection and initiating an effective immune response to fight back against the invasion. Wed, 26 Jul 2023 17:12:46 EDT //www.koonmotors.com/releases/2023/07/230726171246.htm Insect protein slows weight gain, boosts health status in obese mice //www.koonmotors.com/releases/2023/07/230726134219.htm A new study in mice suggests replacing traditional protein sources with mealworms in high-fat diets could slow weight gain, improve immune response, reduce inflammation, enhance energy metabolism, and beneficially alter the ratio of good to bad cholesterol. Wed, 26 Jul 2023 13:42:19 EDT //www.koonmotors.com/releases/2023/07/230726134219.htm Protein found to protect females against obesity //www.koonmotors.com/releases/2023/07/230725171933.htm Using a mouse model of high fat diet-induced obesity, a team of scientists has found that, compared to males, female mice are protected against obesity and inflammation because they secrete more of an immune protein called RELMalpha. Tue, 25 Jul 2023 17:19:33 EDT //www.koonmotors.com/releases/2023/07/230725171933.htm Why we lose fat and muscle during infection //www.koonmotors.com/releases/2023/07/230724122535.htm Scientists discovered that 1) the wasting response to T. brucei infection in mice occurs in two phases, each regulated by different immune cells and 2) fat loss did not benefit the fight against infection, but muscle loss did. The findings inform the development of more effective therapeutics that spare people from wasting and increase our understanding of how wasting influences survival and morbidity across infections, cancers, chronic illnesses, and more. Mon, 24 Jul 2023 12:25:35 EDT //www.koonmotors.com/releases/2023/07/230724122535.htm Hitting reset to start a new embryo //www.koonmotors.com/releases/2023/07/230721113116.htm Scientists show how a fertilized egg cell, or zygote, hits 'reset' so that the newly formed embryo can develop according to its own genetic program. Fri, 21 Jul 2023 11:31:16 EDT //www.koonmotors.com/releases/2023/07/230721113116.htm Bacterial protein found in the urogenital tract may contribute to reduced fertility, birth defects //www.koonmotors.com/releases/2023/07/230717175955.htm A team of researchers published new findings that emphasize the crucial role of the urinary and genital tract microbiota in adverse pregnancy outcomes and genomic instability that originate in the womb during fetal development. The study established a new link between genomic instability and a protein from Mycoplasma fermentans, a kind of bacterium that commonly colonizes the urogenital tract. This bacterial protein also reduced fertility in mother mice and resulted in more birth defects in their newborn pups. Mon, 17 Jul 2023 17:59:55 EDT //www.koonmotors.com/releases/2023/07/230717175955.htm How the immune system can alter our behavior //www.koonmotors.com/releases/2023/07/230712124604.htm Simply the smell of seafood can make those with an allergy to it violently ill -- and therefore more likely to avoid it. The same avoidance behavior is exhibited by people who develop food poisoning after eating a certain meal. Scientists have long known that the immune system played a key role in our reactions to allergens and pathogens in the environment, but it was unclear whether it played any role in prompting these types of behaviors towards allergic triggers. Wed, 12 Jul 2023 12:46:04 EDT //www.koonmotors.com/releases/2023/07/230712124604.htm First bioavailable compound that specifically inhibits free radical production in mitochondria prevents and treats metabolic syndrome in mice //www.koonmotors.com/releases/2023/07/230710113857.htm 老化的自由基理论是在玩fter falling out of favor decades ago. (Remember when people were taking massive doses of various vitamins and minerals? Mopping up free radicals with antioxidants compromised beneficial metabolic signaling pathways leading to bad side effects). What brings the theory back? Researchers at the Buck discovered that they could specifically block free radical production in mitochondria. An elegant solution replaces an indiscriminate and messy mop up. These scientists developed a bioavailable compound -- available in a pill form -- that blocks free radical production. The compound both prevented and treated metabolic syndrome in mice. 'We think that mitochondrial radical production drives many chronic diseases of aging, and that blocking the production of free radicals is a viable disease-treating and anti-aging intervention,' said Martin Brand, Ph.D., Buck Professor Emeritus and senior investigator of the study. Mon, 10 Jul 2023 11:38:57 EDT //www.koonmotors.com/releases/2023/07/230710113857.htm An unexpected doorway into the ear opens new possibilities for hearing restoration //www.koonmotors.com/releases/2023/06/230628201318.htm Researchers have developed a new method to deliver drugs into the inner ear. The discovery was possible by harnessing the natural flow of fluids in the brain and employing a little understood backdoor into the cochlea. When combined to deliver a gene therapy that repairs inner ear hair cells, the researchers were able to restore hearing in deaf mice. Wed, 28 Jun 2023 20:13:18 EDT //www.koonmotors.com/releases/2023/06/230628201318.htm All the immunity, none of the symptoms //www.koonmotors.com/releases/2023/06/230623161139.htm Scientists found pairing specific diets with diarrheal disease-causing bacteria can create lasting immunity in mice without a need to ever experience symptoms. The findings pave the way for vaccine development that could reduce symptoms and mortality of diarrheal illness and other diseases in humans. Fri, 23 Jun 2023 16:11:39 EDT //www.koonmotors.com/releases/2023/06/230623161139.htm Studying herpes encephalitis with mini-brains //www.koonmotors.com/releases/2023/06/230622120820.htm 单纯疱疹virus-1有时会导致一个dangerous brain infection. Combining an anti-inflammatory and an antiviral could help in these cases, report scientists. Thu, 22 Jun 2023 12:08:20 EDT //www.koonmotors.com/releases/2023/06/230622120820.htm Unraveling the connections between the brain and gut //www.koonmotors.com/releases/2023/06/230622120236.htm Engineers designed a technology to probe connections between the brain and the digestive tract. Using fibers embedded with a variety of sensors, as well as optogenetic stimulation, the researchers could control neural circuits connecting the gut and the brain, in mice. Thu, 22 Jun 2023 12:02:36 EDT //www.koonmotors.com/releases/2023/06/230622120236.htm The speed of life: A zoo of cells to study developmental time //www.koonmotors.com/releases/2023/06/230620113815.htm Researchers have used an unprecedented stem cell zoo to compare six different mammalian species and their developmental time. Tue, 20 Jun 2023 11:38:15 EDT //www.koonmotors.com/releases/2023/06/230620113815.htm Elimination of type of bacteria suggests treatment for endometriosis //www.koonmotors.com/releases/2023/06/230614220552.htm A research group has discovered that using an antibiotic to target Fusobacterium, a common bacterium that causes inflammation, improved the symptoms of endometriosis. Their findings suggest an alternative treatment for the disease. Wed, 14 Jun 2023 22:05:52 EDT //www.koonmotors.com/releases/2023/06/230614220552.htm The latest weapon against cancer is ... a keto diet? //www.koonmotors.com/releases/2023/06/230612200434.htm 酮饮食减少胰腺癌和结直肠肿瘤by starving them of the glucose they need to survive. But they also speed up development of a lethal wasting disease called cachexia. In mice, researchers have found that pairing keto with a corticosteroid prevents cachexia and increases survival. Mon, 12 Jun 2023 20:04:34 EDT //www.koonmotors.com/releases/2023/06/230612200434.htm Taurine may be a key to longer and healthier life //www.koonmotors.com/releases/2023/06/230608195654.htm A study finds that deficiency of taurine, a molecule produced in our bodies, drives aging, and taurine supplements can improve health and increase lifespan in animals. Thu, 08 Jun 2023 19:56:54 EDT //www.koonmotors.com/releases/2023/06/230608195654.htm How chronic stress drives the brain to crave comfort food //www.koonmotors.com/releases/2023/06/230608120905.htm Stress can override natural satiety cues to drive more food intake and boost cravings for sweets. Thu, 08 Jun 2023 12:09:05 EDT //www.koonmotors.com/releases/2023/06/230608120905.htm Cutting boards can produce microparticles when chopping veggies //www.koonmotors.com/releases/2023/06/230601155739.htm Cutting boards are handy tools found in most homes and restaurant kitchens. But a small-scale study suggests that they are an overlooked source of micrometer-sized particles. The researchers report that chopping up carrots on wood and plastic boards could produce tens of millions of microparticles a year. However, a toxicity test showed no substantial effect on mouse cell survival from polyethylene or wood microparticles released during chopping. 星期四,01 2023年6月15日:57:39 EDT //www.koonmotors.com/releases/2023/06/230601155739.htm Eat right, live longer: Could a moderate protein diet be the coveted elixir of youth? //www.koonmotors.com/releases/2023/05/230531101947.htm 购买营养食品可以改善代谢alth and delay aging. But what are the appropriate quantities of dietary macronutrients that can help achieve this? To answer this, researchers fed isocaloric diets with varying amounts of protein to young and middle-aged male mice. They found that the mice were metabolically healthier when fed moderate-protein diets. These findings could provide valuable insights into developing nutritional interventions and improving metabolic health in people. Wed, 31 May 2023 10:19:47 EDT //www.koonmotors.com/releases/2023/05/230531101947.htm Researchers show that IgA fine tunes the body's interactions with microbes //www.koonmotors.com/releases/2023/05/230526142236.htm A new study has demonstrated that IgA acts as a 'tuner' that regulates the number of microbes the body sees every day, restraining the systemic immune response to these commensal microbes and limiting the development of systemic immune dysregulation. Fri, 26 May 2023 14:22:36 EDT //www.koonmotors.com/releases/2023/05/230526142236.htm Researchers successfully induce primate oocytes in the lab //www.koonmotors.com/releases/2023/05/230525141343.htm The many types of cells in the human body are produced through the process of differentiation, in which stem cells are converted to more specialized types. Currently, it is challenging for researchers to control the differentiation of stem cells in the lab (in vitro). Of particular interest are oocytes, which are female germ cells that develop into eggs. Understanding their development could have far-ranging impacts, from infertility treatment to conservation of endangered species. A new study has successfully induced meiotic (dividing) oocytes from the embryonic stem cells of cynomolgus monkeys, which share many physiological traits with humans. By establishing a culture method for inducing the differentiation of meiotic oocytes, the researchers aimed to shed light on germ cell development in both humans and other primates. Thu, 25 May 2023 14:13:43 EDT //www.koonmotors.com/releases/2023/05/230525141343.htm The fast and the fibrous: Developing the muscles you need for speed //www.koonmotors.com/releases/2023/05/230525141338.htm Researchers have identified the role of the large Maf transcription factor family in regulating fast twitch muscle fibers. A mouse model lacking Maf expression in the skeletal muscles exhibited a significant loss of type IIb myofibers, a subtype of fast twitch fibers. Overexpression of large Mafs promoted type IIb muscle fiber induction. The large Maf family may represent potential targets for developing treatments for muscular disorders involving fast twitch fibers. Thu, 25 May 2023 14:13:38 EDT //www.koonmotors.com/releases/2023/05/230525141338.htm How tasty is the food? //www.koonmotors.com/releases/2023/05/230524182043.htm A hormone and specialized brain cells regulate feeding behavior in mice. Wed, 24 May 2023 18:20:43 EDT //www.koonmotors.com/releases/2023/05/230524182043.htm Move over, armadillos: There's a new bone-plated mammal in town //www.koonmotors.com/releases/2023/05/230524181855.htm Armadillos have long been considered to be the only living mammals that produce protective bony plates. But a new study unexpectedly shows that African spiny mice produce the same structures beneath the skin of their tails, which until now had gone largely undetected. Wed, 24 May 2023 18:18:55 EDT //www.koonmotors.com/releases/2023/05/230524181855.htm New technique substantially reduces mouse damage to crops even during plagues //www.koonmotors.com/releases/2023/05/230523185028.htm A non-toxic method to prevent mice from devouring wheat crops has been shown to drastically reduce seed loss. Tue, 23 May 2023 18:50:28 EDT //www.koonmotors.com/releases/2023/05/230523185028.htm