//www.koonmotors.com/news/mind_brain/neuroscience/ Neuroscience research. Learn how the brain's physical, chemical and electrical structure can affect everything from motivation and sensory perception to disease recovery. en-us Thu, 07 Sep 2023 22:49:30 EDT Thu, 07 Sep 2023 22:49:30 EDT 60 //www.koonmotors.com/images/scidaily-logo-rss.png//www.koonmotors.com/news/mind_brain/neuroscience/ For more science news, visit ScienceDaily. //www.koonmotors.com/releases/2023/09/230907130318.htm In many neurodegenerative disorders, abnormal proteins progressively aggregate and propagate in the brain. But what comes first, aggregation or propagation? Researchers from Japan share some new insights about the mechanism involved in Parkinson's disease. Thu, 07 Sep 2023 13:03:18 EDT //www.koonmotors.com/releases/2023/09/230907130318.htm //www.koonmotors.com/releases/2023/09/230906161815.htm A study of twins shows that having a concussion early in life is tied to having lower scores on tests of thinking and memory skills decades later as well as having more rapid decline in those scores than twins who did not have a concussion, or traumatic brain injury (TBI). Wed, 06 Sep 2023 16:18:15 EDT //www.koonmotors.com/releases/2023/09/230906161815.htm //www.koonmotors.com/releases/2023/09/230906143449.htm Researchers have designed a device that can help test treatments in patients with gliomas, a type of tumor that originates in the brain or spinal cord. Wed, 06 Sep 2023 14:34:49 EDT //www.koonmotors.com/releases/2023/09/230906143449.htm //www.koonmotors.com/releases/2023/09/230906143429.htm Not only does a lack of sleep make you feel awful, research has shown it impairs the brain. What's more, sleep loss over long periods can even increase risk for Alzheimer's and other neurological diseases. Researchers want to understand how sleep deprivation causes this harm. In a new study, a team working with mice has identified a protective protein whose level declines with sleep deprivation, leading to neuronal death. Wed, 06 Sep 2023 14:34:29 EDT //www.koonmotors.com/releases/2023/09/230906143429.htm //www.koonmotors.com/releases/2023/09/230906115607.htm A groundbreaking study has shed new light on the genetic underpinnings of Alzheimer's disease. Wed, 06 Sep 2023 11:56:07 EDT //www.koonmotors.com/releases/2023/09/230906115607.htm //www.koonmotors.com/releases/2023/09/230906112434.htm An international study tested transcranial direct current stimulation (tDCS) on 62 patients suffering from consciousness disorders following severe brain injury. These results represent a significant advance in how we care for these patients and will enable us to refine the therapeutic strategies to implement. Wed, 06 Sep 2023 11:24:34 EDT //www.koonmotors.com/releases/2023/09/230906112434.htm //www.koonmotors.com/releases/2023/09/230906112412.htm Neuroscientists created the first non-human primate model of hereditary Alzheimer's in marmosets to accelerate the pace of drug discovery and rebuild the foundation for future translational studies. Wed, 06 Sep 2023 11:24:12 EDT //www.koonmotors.com/releases/2023/09/230906112412.htm //www.koonmotors.com/releases/2023/09/230905155717.htm Researchers have discovered a new avenue of cell death in Alzheimer's disease and vascular dementia. The study reveals for the first time that a form of cell death known as ferroptosis -- caused by a buildup of iron in cells -- destroys microglia cells in cases of Alzheimer's and vascular dementia. Tue, 05 Sep 2023 15:57:17 EDT //www.koonmotors.com/releases/2023/09/230905155717.htm //www.koonmotors.com/releases/2023/09/230905125028.htm Nineteen-month-old toddlers already use natural logical thinking, even before they learn to speak, to deal with uncertainties about the world. This natural logic contributes to their learning process, both in terms of language and in other fields of knowledge, according to a new study. Tue, 05 Sep 2023 12:50:28 EDT //www.koonmotors.com/releases/2023/09/230905125028.htm //www.koonmotors.com/releases/2023/09/230905124926.htm The school year has hardly begun and the first exams are already approaching. According to findings by researchers from the University of Basel, school children cope better with the stress if they get plenty of daily exercise. Tue, 05 Sep 2023 12:49:26 EDT //www.koonmotors.com/releases/2023/09/230905124926.htm //www.koonmotors.com/releases/2023/09/230905124915.htm Scientists have shed new light on the role of GABA, a key signaling molecule in the brain. Researchers have delved into how GABA's levels in the brain are regulated and its broader impacts on cognitive function. Tue, 05 Sep 2023 12:49:15 EDT //www.koonmotors.com/releases/2023/09/230905124915.htm //www.koonmotors.com/releases/2023/09/230901124042.htm A study sheds new light on why tumors that have spread to the brain from other parts of the body respond to immunotherapy while glioblastoma, an aggressive cancer that originates in the brain, does not. Fri, 01 Sep 2023 12:40:42 EDT //www.koonmotors.com/releases/2023/09/230901124042.htm //www.koonmotors.com/releases/2023/08/230831142832.htm The largest genetic study of its kind has discovered specific changes in our DNA that increase the risk of developing epilepsy and may inform the development of new treatments. Thu, 31 Aug 2023 14:28:32 EDT //www.koonmotors.com/releases/2023/08/230831142832.htm //www.koonmotors.com/releases/2023/08/230831142823.htm New research has shown how a complex component of milk that can be added to infant formula has been shown to confer long-term cognitive benefits, including measures of intelligence and executive function in children. Thu, 31 Aug 2023 14:28:23 EDT //www.koonmotors.com/releases/2023/08/230831142823.htm //www.koonmotors.com/releases/2023/08/230831142812.htm A new article examines the use of monoclonal antibody therapies for treating Alzheimer disease and alerts physicians to be on the lookout for a potential side effect: amyloid-related imaging abnormalities. Thu, 31 Aug 2023 14:28:12 EDT //www.koonmotors.com/releases/2023/08/230831142812.htm //www.koonmotors.com/releases/2023/08/230831142801.htm 神经科学的主要关键是学习我们nses translate light into sight, sound into hearing, food into taste, and texture into touch. Smell is where these sensory relationships get more complex and perplexing. To address this question, a research team are investigating how airborne chemicals connect to odor perception in the brain. They discovered that a machine-learning model has achieved human-level proficiency at describing, in words, what chemicals smell like. Thu, 31 Aug 2023 14:28:01 EDT //www.koonmotors.com/releases/2023/08/230831142801.htm //www.koonmotors.com/releases/2023/08/230831142748.htm Exciting a brain region using electrical noise stimulation can help improve mathematical learning in those who struggle with the subject, according to a new study. Thu, 31 Aug 2023 14:27:48 EDT //www.koonmotors.com/releases/2023/08/230831142748.htm //www.koonmotors.com/releases/2023/08/230831121807.htm 一个名为p-tau217的新血液测试显示了承诺an Alzheimer's disease biomarker, and when used in a two-step workflow very high accuracy to either identify or exclude brain amyloidosis, the most important and earliest pathology. Thu, 31 Aug 2023 12:18:07 EDT //www.koonmotors.com/releases/2023/08/230831121807.htm //www.koonmotors.com/releases/2023/08/230831121624.htm This is a significant development that brings hope to the one billion individuals with obesity worldwide. Researchers have discovered new insights into the regulation of fat metabolism. The focus of their study lies within the star-shaped non-neuronal cells in the brain, known as 'astrocytes'. Furthermore, the group announced successful animal experiments using the newly developed drug 'KDS2010', which allowed the mice to lose weigh without dietary restrictions. Thu, 31 Aug 2023 12:16:24 EDT //www.koonmotors.com/releases/2023/08/230831121624.htm //www.koonmotors.com/releases/2023/08/230830151742.htm Researchers have developed a blood test that detects Parkinson's disease, potentially establishing a way to help diagnose the condition before nervous system damage worsens. A new blood-based diagnostic test would be a major advancement for Parkinson's disease, which afflicts 10 million people worldwide and is the second-most common neurodegenerative disease after Alzheimer's. Wed, 30 Aug 2023 15:17:42 EDT //www.koonmotors.com/releases/2023/08/230830151742.htm //www.koonmotors.com/releases/2023/08/230830131956.htm Scientists have made a 'paradigm shifting' discovery on the mechanisms required for learning and memory that could lead to new therapies for Alzheimer's disease and potentially Down syndrome. Wed, 30 Aug 2023 13:19:56 EDT //www.koonmotors.com/releases/2023/08/230830131956.htm //www.koonmotors.com/releases/2023/08/230830131943.htm Disrupted connections between memory and appetite regulating brain circuits are directly proportional to body mass index (BMI), notably in patients who suffer from disordered or overeating that can lead to obesity, such as binge eating disorder (BED), according to new research. The research notes that individuals who are obese have impaired connections between the dorsolateral hippocampus (dlHPC) and the lateral hypothalamus (LH), which may impact their ability to control or regulate emotional responses when anticipating rewarding meals or treats. Wed, 30 Aug 2023 13:19:43 EDT //www.koonmotors.com/releases/2023/08/230830131943.htm //www.koonmotors.com/releases/2023/08/230830131903.htm How much is adequate screen time for a child? It is the question at the forefront of many parents' minds. Now, a recent cohort study has found that the amount of screen time spent by one-year-olds is associated with developmental delays. Wed, 30 Aug 2023 13:19:03 EDT //www.koonmotors.com/releases/2023/08/230830131903.htm //www.koonmotors.com/releases/2023/08/230830131703.htm A new study suggests that cognitive loss in patients with brain metastases may be due to the interference that cancer produces in neuronal circuits. When cancer spreads in the brain, it changes the brain's chemistry, interfering with the communication between neurons. This is a very different hypothesis from the one previously accepted, with implications for the diagnosis and treatment of brain metastases. The authors have used artificial intelligence to show that metastasis alters brain activity. Wed, 30 Aug 2023 13:17:03 EDT //www.koonmotors.com/releases/2023/08/230830131703.htm //www.koonmotors.com/releases/2023/08/230830130817.htm Researchers used wireless neural recording and imaging devices to 'listen in' on the hippocampal brain activity of groups of Egyptian fruit bats as they flew freely within a large flight room. The researchers were surprised to find that, in this social setting, the bat's 'place' neurons encoded not only the animal's location, but also information about the presence or absence of other bats, and even the identity of bats in their path. Wed, 30 Aug 2023 13:08:17 EDT //www.koonmotors.com/releases/2023/08/230830130817.htm //www.koonmotors.com/releases/2023/08/230829125934.htm A new study shows that people suffering from hospital-treated depression may have a high risk of developing conditions such as substance abuse, bipolar disorder, schizophrenia and anxiety -- depending on their genetic predisposition to the individual disorder. Tue, 29 Aug 2023 12:59:34 EDT //www.koonmotors.com/releases/2023/08/230829125934.htm //www.koonmotors.com/releases/2023/08/230829125919.htm Damage associated with Alzheimer's disease begins within hours after a concussion according to results from research that uses a 'mini-brain' lab on a chip device. Tue, 29 Aug 2023 12:59:19 EDT //www.koonmotors.com/releases/2023/08/230829125919.htm //www.koonmotors.com/releases/2023/08/230829125813.htm A potential new Alzheimer's drug represses the harmful inflammatory response of the brain's immune cells, reducing disease pathology, preserving neurons and improving cognition in preclinical tests. Tue, 29 Aug 2023 12:58:13 EDT //www.koonmotors.com/releases/2023/08/230829125813.htm //www.koonmotors.com/releases/2023/08/230829125809.htm Brucellosis is a disease, caused by the members of bacterial Brucella family, that mainly infects cattle, goats and sheep, leading to pregnancy loss, which has caused billions of dollars in economic losses for livestock producers worldwide. The disease can also jump from animals to humans, mainly through consumption of unpasteurized dairy products or inhaling the spores from the tissues of infected animals. While the disease can cause arthritis, inflammation of the heart and flu-like symptoms in humans, the bacteria can also enter the brain and cause neurobrucellosis, which can lead to long-term neurological complications, headaches, nausea, disorientation, swelling of the brain and sometimes death. Now, a new study has highlighted the protective power of both innate lymphoid cells and specific signaling proteins, known as interferons, in reducing the harmful neurological effects of Brucella. Tue, 29 Aug 2023 12:58:09 EDT //www.koonmotors.com/releases/2023/08/230829125809.htm //www.koonmotors.com/releases/2023/08/230829124717.htm Sleep is a critical part of a child's overall health, but it can also be an important factor in the way they behave. According to a new study, getting enough sleep can help children combat the effects of stressful environments. Tue, 29 Aug 2023 12:47:17 EDT //www.koonmotors.com/releases/2023/08/230829124717.htm //www.koonmotors.com/releases/2023/08/230828130347.htm Researchers have succeeded in transforming brain signals into audible speech. By decoding signals from the brain through a combination of implants and AI, they were able to predict the words people wanted to say with an accuracy of 92 to 100%. Mon, 28 Aug 2023 13:03:47 EDT //www.koonmotors.com/releases/2023/08/230828130347.htm //www.koonmotors.com/releases/2023/08/230825122006.htm In the new study, the team used the model to demonstrate that as Alzheimer's pathology accumulates in the brain, specific types of immune cells called CT8+ T Cells surge into the brain and amplify the destruction caused by neuroinflammation. Fri, 25 Aug 2023 12:20:06 EDT //www.koonmotors.com/releases/2023/08/230825122006.htm //www.koonmotors.com/releases/2023/08/230824150719.htm Short-lived proteins control gene expression in cells to carry out a number of vital tasks, from helping the brain form connections to helping the body mount an immune defense. These proteins are made in the nucleus and are quickly destroyed once they've done their job. The mechanism degrades short-lived proteins that support brain and immune functions. Thu, 24 Aug 2023 15:07:19 EDT //www.koonmotors.com/releases/2023/08/230824150719.htm //www.koonmotors.com/releases/2023/08/230824003818.htm Biomedical engineers have developed sophisticated optical techniques to monitor at close range the process by which protein aggregates form during liquid-to-liquid transition. This can lead to solid condensates which can trigger a process that forms neural plaques, that can cause Alzheimer's and other diseases. Thu, 24 Aug 2023 00:38:18 EDT //www.koonmotors.com/releases/2023/08/230824003818.htm //www.koonmotors.com/releases/2023/08/230823122623.htm Researchers make progress in developing a digital biomarker that detects early signs of Alzheimer's disease in brainwave patterns using a simple 'wearable' headband at night. Wed, 23 Aug 2023 12:26:23 EDT //www.koonmotors.com/releases/2023/08/230823122623.htm //www.koonmotors.com/releases/2023/08/230823122530.htm Researchers have developed a brain-computer interface (BCI) that has enabled a woman with severe paralysis from a brainstem stroke to speak through a digital avatar. Wed, 23 Aug 2023 12:25:30 EDT //www.koonmotors.com/releases/2023/08/230823122530.htm //www.koonmotors.com/releases/2023/08/230822151748.htm Many researchers believe that the neurodegenerative disorder gets started in the gut. Research now suggests that an autoimmune reaction may be driving those early events. Tue, 22 Aug 2023 15:17:48 EDT //www.koonmotors.com/releases/2023/08/230822151748.htm //www.koonmotors.com/releases/2023/08/230822151729.htm A new study uses more genetically diverse mouse models to study the accumulation and spread of abnormal tau protein deposits in the brain -- a known sign of Alzheimer's disease and several other neurodegenerative diseases. Tue, 22 Aug 2023 15:17:29 EDT //www.koonmotors.com/releases/2023/08/230822151729.htm //www.koonmotors.com/releases/2023/08/230822111716.htm Everyday symbols like &?!#@$ are highly memorable, according to new research. The new study aimed to investigate how well symbols are remembered compared to words with the same meaning. Tue, 22 Aug 2023 11:17:16 EDT //www.koonmotors.com/releases/2023/08/230822111716.htm //www.koonmotors.com/releases/2023/08/230821153213.htm 新的研究结果表明,间歇性禁食外壳d be an effective treatment approach for Alzheimer's disease. Mice fed on a time-restricted schedule had better memory and less accumulation of amyloid proteins in the brain compared to controls. Mon, 21 Aug 2023 15:32:13 EDT //www.koonmotors.com/releases/2023/08/230821153213.htm //www.koonmotors.com/releases/2023/08/230821135640.htm A new study has demonstrated the ability for gene therapy to repair neural connections for those with the rare genetic brain disorder known as Hurler syndrome. Mon, 21 Aug 2023 13:56:40 EDT //www.koonmotors.com/releases/2023/08/230821135640.htm //www.koonmotors.com/releases/2023/08/230821114415.htm Researchers model and map how neurons across the tiny brain of a C. elegans worm encode its behaviors, revealing many new insights about the robustness and flexibility of its nervous system. Mon, 21 Aug 2023 11:44:15 EDT //www.koonmotors.com/releases/2023/08/230821114415.htm //www.koonmotors.com/releases/2023/08/230821114333.htm 基因病毒自然pre的残余sent in the human genome could affect the development of neurodegenerative diseases. Researchers come to this conclusion on the basis of studies on cell cultures. Mon, 21 Aug 2023 11:43:33 EDT //www.koonmotors.com/releases/2023/08/230821114333.htm //www.koonmotors.com/releases/2023/08/230818004425.htm Amyotrophic lateral sclerosis (ALS) is a widespread neurodegenerative disease caused by the loss of neurons that control movement. Although abnormal accumulation of proteins called TDP-43 accompanies ALS, its role in disease progression is not well understood. Recently, using novel mouse models of ALS, researchers have identified the neurological spreading patterns through which TDP-43 perpetuates the degeneration of the movement-related neural circuitry. Fri, 18 Aug 2023 00:44:25 EDT //www.koonmotors.com/releases/2023/08/230818004425.htm //www.koonmotors.com/releases/2023/08/230817164030.htm Researchers have found an injection of a specific blood factor can replicate the benefits of exercise in the brain. They've discovered that platelets secrete a protein, exerkine CXCL4/Platelet factor 4 or PF4, that rejuvenates neurons in aged mice in a similar way to physical exercise. This protein, which is released from platelets after exercise, results in regenerative and cognitive improvements when injected into aged mice. Thu, 17 Aug 2023 16:40:30 EDT //www.koonmotors.com/releases/2023/08/230817164030.htm //www.koonmotors.com/releases/2023/08/230817164008.htm Researchers are using mathematical models to better understand the effects of disruptions like daylight savings time, working night shifts, jet lag or even late-night phone scrolling on the body's circadian rhythms. Thu, 17 Aug 2023 16:40:08 EDT //www.koonmotors.com/releases/2023/08/230817164008.htm //www.koonmotors.com/releases/2023/08/230817164006.htm According to a recent study, improved overall diet quality and reduced consumption of red meat, as well as increased time spent in reading and organized sports enhanced reasoning skills among children over the first two school years. Thu, 17 Aug 2023 16:40:06 EDT //www.koonmotors.com/releases/2023/08/230817164006.htm //www.koonmotors.com/releases/2023/08/230817163956.htm When choosing their behavior in socially difficult situations, anxious people use a less suitable section of the forebrain than people who are not anxious. Thu, 17 Aug 2023 16:39:56 EDT //www.koonmotors.com/releases/2023/08/230817163956.htm //www.koonmotors.com/releases/2023/08/230817163943.htm New animal research suggests that little-studied brain cells known as astrocytes are major players in controlling sleep need and may someday help humans go without sleep for longer without negative consequences such as mental fatigue and impaired physical health. The study found that activating these cells kept mice awake for hours when they would normally be resting, without making them any sleepier. The researchers said their findings open up the possibility of future interventions that could target astrocytes to mitigate the negative consequences of prolonged wakefulness. which would benefit the productivity, safety, and health of shift workers and others who work long or odd hours. Thu, 17 Aug 2023 16:39:43 EDT //www.koonmotors.com/releases/2023/08/230817163943.htm //www.koonmotors.com/releases/2023/08/230817163940.htm Somatostatin, a signaling molecule produced by many inhibitory neurons in the brain, broadly dampens communication among a variety of cell types in the prefrontal cortex and promotes exploratory and risk-taking-like behavior in mice. Thu, 17 Aug 2023 16:39:40 EDT //www.koonmotors.com/releases/2023/08/230817163940.htm //www.koonmotors.com/releases/2023/08/230817163935.htm Neuroscientists report the first results from experimental tests designed to explore the idea that 'forgetting' might not be a bad thing, and that it may represent a form of learning -- and outline results that support their core idea. Seemingly lost memories can be retrieved and updated by environmental cues, which means this research has implications for a range of diseases such as Alzheimer's. Thu, 17 Aug 2023 16:39:35 EDT //www.koonmotors.com/releases/2023/08/230817163935.htm //www.koonmotors.com/releases/2023/08/230817163925.htm A team of researchers has demonstrated that the key to understanding working memory relies not only on what one is storing in memory, but also why. This is the 'working' part of working memory, which emphasizes the purpose of storing something in the first place. Thu, 17 Aug 2023 16:39:25 EDT //www.koonmotors.com/releases/2023/08/230817163925.htm //www.koonmotors.com/releases/2023/08/230817163922.htm The largest ever study of the genetics of the brain -- encompassing some 36,000 brain scans -- has identified more than 4,000 genetic variants linked to brain structure. Thu, 17 Aug 2023 16:39:22 EDT //www.koonmotors.com/releases/2023/08/230817163922.htm //www.koonmotors.com/releases/2023/08/230817163920.htm Obesity leads to altered energy metabolism and reduced insulin sensitivity of cells. The so-called 'anti-obesity drugs' are increasingly used to treat obesity and have caused tremendous interest, especially in the USA. Researchers have now shown in people with obesity that reduced insulin sensitivity affects learning of sensory associations. A single dose of the anti-obesity drug liraglutide was able to normalize these changes and restore the underlying brain circuit function. Thu, 17 Aug 2023 16:39:20 EDT //www.koonmotors.com/releases/2023/08/230817163920.htm //www.koonmotors.com/releases/2023/08/230817163900.htm An international team of scientists has discovered an additional potential cause of the genetic mutations that result in rare neurodegenerative conditions such as Huntington's disease. Thu, 17 Aug 2023 16:39:00 EDT //www.koonmotors.com/releases/2023/08/230817163900.htm //www.koonmotors.com/releases/2023/08/230816160024.htm Cranial modification is a form of body alteration where the head is pressed or bound to permanently deform the skull. The practice has been reported across various cultures throughout history. Researchers report that the Hirota people -- who lived on the southern Japanese island of Tanegashima between the 3rd to 7th century CE -- also conducted cranial modification, with indication that both males and females performed the practice. Wed, 16 Aug 2023 16:00:24 EDT //www.koonmotors.com/releases/2023/08/230816160024.htm //www.koonmotors.com/releases/2023/08/230816160006.htm Researcher discovers possible link of mitochondrial function to the development of schizophrenia. Wed, 16 Aug 2023 16:00:06 EDT //www.koonmotors.com/releases/2023/08/230816160006.htm //www.koonmotors.com/releases/2023/08/230816160003.htm Scientists have uncovered how a newly discovered gene, NEK1, in which mutations have been linked to ALS cases, disrupts the function of the motor neuron and causes it to degenerate and die. Wed, 16 Aug 2023 16:00:03 EDT //www.koonmotors.com/releases/2023/08/230816160003.htm //www.koonmotors.com/releases/2023/08/230816114222.htm Scientists' discovery could lead to new weight loss and metabolic health treatments. Wed, 16 Aug 2023 11:42:22 EDT //www.koonmotors.com/releases/2023/08/230816114222.htm //www.koonmotors.com/releases/2023/08/230816114207.htm Can you recognize an old friend, but forget what you had for breakfast yesterday? Our brains constantly rearrange their circuitry to retain information, but the molecular basis behind this process isn't well understood. New research suggests that complex sugars called glycosaminoglycans might play a major role in the 'plasticity' of the brains of mice and could be used to repair neural connections after injury. Wed, 16 Aug 2023 11:42:07 EDT //www.koonmotors.com/releases/2023/08/230816114207.htm