//www.koonmotors.com/news/mind_brain/mad_cow_disease/ Learn all about mad cow disease, TSE, and the prions that cause the disease. Current science articles on symptoms, prevention and more. en-us Fri, 08 Sep 2023 08:18:56 EDT Fri, 08 Sep 2023 08:18:56 EDT 60 //www.koonmotors.com/images/scidaily-logo-rss.png//www.koonmotors.com/news/mind_brain/mad_cow_disease/ For more science news, visit ScienceDaily. //www.koonmotors.com/releases/2022/11/221117184201.htm The brains of people with Down syndrome develop the same neurodegenerative tangles and plaques associated with Alzheimer's disease and frequently demonstrate signs of the neurodegenerative disorder in their forties or fifties. A new study shows that these tangles and plaques are driven by the same amyloid beta and tau prions that researchers showed are behind Alzheimer's disease in 2019. Thu, 17 Nov 2022 18:42:01 EST //www.koonmotors.com/releases/2022/11/221117184201.htm //www.koonmotors.com/releases/2022/03/220317111917.htm A promising new treatment for Creutzfeldt-Jakob disease (CJD) has shown 'very encouraging' early results following its use in six patients. Thu, 17 Mar 2022 11:19:17 EDT //www.koonmotors.com/releases/2022/03/220317111917.htm //www.koonmotors.com/releases/2022/01/220105151348.htm An international team has made a significant breakthrough in understanding why Alzheimer's disease progresses so rapidly in some people that they die within three years. The researchers found a link between strains of misshapen and fast-replicating tau protein and accelerated cognitive decline -- a critical result that illuminates the variations in Alzheimer's disease and could help lead to more precise diagnoses and targeted therapies. Such work could lead to changes in Alzheimer's care, possibly giving patients and families more accurate prognoses. Wed, 05 Jan 2022 15:13:48 EST //www.koonmotors.com/releases/2022/01/220105151348.htm //www.koonmotors.com/releases/2021/12/211222153003.htm Prion diseases, such as Creutzfeldt-Jakob Disease (CJD), are fast-moving, fatal dementia syndromes associated with the formation of aggregates of the prion protein, PrP. How these aggregates form within and kill brain cells has never been fully understood, but a new study suggests that the aggregates kill neurons by damaging their axons, the narrow nerve fibers through which they send signals to other neurons. Wed, 22 Dec 2021 15:30:03 EST //www.koonmotors.com/releases/2021/12/211222153003.htm //www.koonmotors.com/releases/2021/11/211115151030.htm Prions, aggregates implicated in neurological diseases, may also have an important function in helping regulate the transcription of messenger RNA in memory formation. Mon, 15 Nov 2021 15:10:30 EST //www.koonmotors.com/releases/2021/11/211115151030.htm //www.koonmotors.com/releases/2021/10/211019120145.htm Some viral diseases could possibly contribute to neurodegeneration. Researchers found that certain viral molecules facilitated intercellular spreading of protein aggregates that are hallmarks of brain diseases like Alzheimer's. These findings may provide clues how acute or chronic viral infections could contribute to neurodegeneration. Tue, 19 Oct 2021 12:01:45 EDT //www.koonmotors.com/releases/2021/10/211019120145.htm //www.koonmotors.com/releases/2021/06/210617143659.htm Researchers studying prions -- misfolded proteins that cause lethal incurable diseases -- have identified the surface features of human prions responsible for their replication in the brain. Thu, 17 Jun 2021 14:36:59 EDT //www.koonmotors.com/releases/2021/06/210617143659.htm //www.koonmotors.com/releases/2021/03/210315165637.htm Researchers have pinpointed what causes normal proteins to convert to a diseased form, causing conditions like CJD and Kuru. Mon, 15 Mar 2021 16:56:37 EDT //www.koonmotors.com/releases/2021/03/210315165637.htm //www.koonmotors.com/releases/2020/11/201117113056.htm Alzheimer's disease develops over decades. It begins with a fatal chain reaction in which masses of misfolded beta-amyloid proteins are produced that in the end literally flood the brain. Researchers now show that this chain reaction starts much earlier in mice than commonly assumed. Tue, 17 Nov 2020 11:30:56 EST //www.koonmotors.com/releases/2020/11/201117113056.htm //www.koonmotors.com/releases/2020/10/201019103459.htm Creutzfeldt-Jakob disease (CJD), a fatal neurodegenerative disorder, is an important cause of dementia. However, long-term trends in CJD-associated mortality and incidence rates in Japan have not been fully studied until now. Now, scientists conducted a detailed analysis that uncovered that the CJD-associated death and incidence rates almost doubled from 2005-2014. They predict that the burden of CJD would continue to rise in the current hyper-aging era. These findings can help policymakers plan and strategize effectively. Mon, 19 Oct 2020 10:34:59 EDT //www.koonmotors.com/releases/2020/10/201019103459.htm //www.koonmotors.com/releases/2020/06/200609144455.htm Human prion diseases include Creutzfeldt-Jakob disease (CJD) and Gerstmann-Sträussler-Scheinker disease (GSS). A new study reports a significant advance in the development of mouse models of human prion diseases. The study demonstrates spontaneous formation of disease-relevant, transmissible prion protein assemblies in mice bearing only human forms of the prion protein. Tue, 09 Jun 2020 14:44:55 EDT //www.koonmotors.com/releases/2020/06/200609144455.htm //www.koonmotors.com/releases/2020/05/200505190552.htm 生物化学和分子生物学教授爱博网投领导者report an unanticipated role for prion nucleation seeds that enhances their ability to appear and resist curing. Tue, 05 May 2020 19:05:52 EDT //www.koonmotors.com/releases/2020/05/200505190552.htm //www.koonmotors.com/releases/2020/04/200406140106.htm Prions are a class of misfolded proteins that form aggregates called "amyloid fibrils." These aggregates are the main culprit behind severe mammalian neurodegenerative diseases like Alzheimer's. What makes them so deadly is that they are capable of transmitting their erroneous conformation to otherwise healthy proteins, causing an imbalance in cellular function. Currently, there are no effective treatments for fatal prion diseases, mainly because studying mammalian prions is challenging. Mon, 06 Apr 2020 14:01:06 EDT //www.koonmotors.com/releases/2020/04/200406140106.htm //www.koonmotors.com/releases/2019/08/190801180925.htm Scientists using an experimental treatment have slowed the progression of scrapie, a degenerative central nervous disease caused by prions, in laboratory mice and greatly extended the rodents' lives. The scientists used antisense oligonucleotides (ASOs), synthetic compounds that inhibit the formation of specific proteins. Thu, 01 Aug 2019 18:09:25 EDT //www.koonmotors.com/releases/2019/08/190801180925.htm //www.koonmotors.com/releases/2019/06/190614111934.htm Scientists have used human skin cells to create what they believe is the first cerebral organoid system, or 'mini-brain,' for studying sporadic Creutzfeldt-Jakob disease (CJD). CJD is a fatal neurodegenerative brain disease of humans believed to be caused by infectious prion protein. The researchers hope the human organoid model will enable them to evaluate potential CJD therapeutics and provide greater detail about human prion disease subtypes. Fri, 14 Jun 2019 11:19:34 EDT //www.koonmotors.com/releases/2019/06/190614111934.htm //www.koonmotors.com/releases/2019/05/190501153358.htm Two proteins central to the pathology of Alzheimer's disease act as prions -- misshapen proteins that spread through tissue like an infection by forcing normal proteins to adopt the same misfolded shape -- according to new research. Wed, 01 May 2019 15:33:58 EDT //www.koonmotors.com/releases/2019/05/190501153358.htm //www.koonmotors.com/releases/2019/03/190327131911.htm Scientists studying the progression of inherited and infectious eye diseases that can cause blindness have found that microglia, a type of nervous system cell suspected to cause retinal damage, surprisingly had no damaging role during prion disease in mice. In contrast, the study findings indicated that microglia might delay disease progression. Wed, 27 Mar 2019 13:19:11 EDT //www.koonmotors.com/releases/2019/03/190327131911.htm //www.koonmotors.com/releases/2019/03/190312170807.htm More than 30 years ago, scientists discovered that mad cow and Creutzfeldt-Jakob diseases are caused by prions. But in recent years, Nobel laureate Eric Kandel, M.D., demonstrated in mice that some prions are beneficial and serve important functions in the brain and body. And today, new research from Dr. Kandel describes how one such prion-like protein helps the brain keep fearful memories in check. Without it, female mice exhibit the tell-tale signs of post-traumatic stress disorder, or PTSD. Tue, 12 Mar 2019 17:08:07 EDT //www.koonmotors.com/releases/2019/03/190312170807.htm //www.koonmotors.com/releases/2019/02/190207115006.htm There is growing evidence that at least in some patients with Parkinson's disease (PD), the disease may begin in the gut. Experts explore the last two decades of research about the gut-brain axis in PD and look ahead at the possible development and impact of these research areas in the next two decades. Thu, 07 Feb 2019 11:50:06 EST //www.koonmotors.com/releases/2019/02/190207115006.htm //www.koonmotors.com/releases/2018/12/181220111810.htm An ultrasensitive test has been developed that detects a corrupted protein associated with Alzheimer's disease and chronic traumatic encephalopathy (CTE), a condition found in athletes, military veterans, and others with a history of repetitive brain trauma. This advance could lead to early diagnosis of these conditions and open new research into how they originate. Thu, 20 Dec 2018 11:18:10 EST //www.koonmotors.com/releases/2018/12/181220111810.htm //www.koonmotors.com/releases/2018/11/181129142438.htm The spread of prions to the brain does not occur by direct transmission across the blood-brain barrier, according to a new study. As noted by the authors, insights into how prions enter the brain could lead to the development of effective strategies to prevent neurodegeneration, even after infection outside the nervous system has already taken place. Thu, 29 Nov 2018 14:24:38 EST //www.koonmotors.com/releases/2018/11/181129142438.htm //www.koonmotors.com/releases/2018/11/181129142435.htm A major compound in soil organic matter degrades chronic wasting disease prions and decreases infectivity in mice, according to a new study. Thu, 29 Nov 2018 14:24:35 EST //www.koonmotors.com/releases/2018/11/181129142435.htm //www.koonmotors.com/releases/2018/10/181018141118.htm The first example of prion strains that replicate independently in vitro and in vivo suggests that strain diversity may be greater than previously thought, according to a new study. Thu, 18 Oct 2018 14:11:18 EDT //www.koonmotors.com/releases/2018/10/181018141118.htm //www.koonmotors.com/releases/2018/09/180921113459.htm A new study has shed light on the mechanisms underlying the progression of prion diseases and identified a potential target for treatment. Fri, 21 Sep 2018 11:34:59 EDT //www.koonmotors.com/releases/2018/09/180921113459.htm //www.koonmotors.com/releases/2018/07/180705114041.htm Scientists have identified a physical basis for the spread of corrupted proteins known as prions inside cells. Thu, 05 Jul 2018 11:40:41 EDT //www.koonmotors.com/releases/2018/07/180705114041.htm //www.koonmotors.com/releases/2018/06/180605172511.htm Researchers have synthesized the first artificial human prion, a dramatic development in efforts to combat a devastating form of brain disease that has so far eluded treatment and a cure. Tue, 05 Jun 2018 17:25:11 EDT //www.koonmotors.com/releases/2018/06/180605172511.htm //www.koonmotors.com/releases/2018/05/180517113755.htm Prion diseases are slow degenerative brain diseases that occur in people and various other mammals. No vaccines or treatments are available, and these diseases are almost always fatal. Scientists have found little evidence of a protective immune response to prion infections. Further, microglia -- brain cells usually involved in the first level of host defense against infections of the brain -- have been thought to worsen these diseases by secreting toxic molecules that can damage nerve cells. Thu, 17 May 2018 11:37:55 EDT //www.koonmotors.com/releases/2018/05/180517113755.htm //www.koonmotors.com/releases/2018/02/180215105753.htm Amyloid beta pathology -- protein deposits in the brain - might have been transmitted by contaminated neurosurgical instruments, suggests a new study. Researchers studied the medical records of four people who had brain bleeds caused by amyloid beta build-up in brain blood vessels. All four people had undergone neurosurgery two or three decades earlier as children or teenagers, raising the possibility that amyloid beta deposition may be transmissible. Thu, 15 Feb 2018 10:57:53 EST //www.koonmotors.com/releases/2018/02/180215105753.htm //www.koonmotors.com/releases/2018/02/180209131433.htm Scientists have modified a test for early diagnosis of prion diseases with the goal of improving early diagnosis of Parkinson's disease and dementia with Lewy bodies. The group tested cerebral spinal fluid samples from people with Parkinson's disease; people with dementia with Lewy bodies; and controls, some of whom had Alzheimer's disease. The test correctly excluded all the controls and diagnosed both Parkinson's disease and dementia with Lewy bodies with 93 percent accuracy. Fri, 09 Feb 2018 13:14:33 EST //www.koonmotors.com/releases/2018/02/180209131433.htm //www.koonmotors.com/releases/2018/01/180109102755.htm Prions are self-propagating protein aggregates that can be transmitted between cells. The aggregates are associated with human diseases. Indeed, pathological prions cause mad cow disease and in humans Creutzfeldt-Jakob disease. The aggregation of prion-like proteins is also associated with neurodegeneration as in ALS. Tue, 09 Jan 2018 10:27:55 EST //www.koonmotors.com/releases/2018/01/180109102755.htm //www.koonmotors.com/releases/2017/12/171201104049.htm Scientists may have found possible targets for therapeutic interventions in the fight against Lou Gehrig's disease. A research team conducted the first single-molecule study of folding in the protein superoxide dismutase-1 (SOD1), an antioxidant whose misfolding is linked to the neurodegenerative disease ALS. They found that it has much more complex folding than previously thought. Fri, 01 Dec 2017 10:40:49 EST //www.koonmotors.com/releases/2017/12/171201104049.htm //www.koonmotors.com/releases/2017/11/171120111306.htm Scientists have developed a new system to study Creutzfeldt-Jakob disease in the laboratory, paving the way for research to find treatments for the fatal brain disorder. Mon, 20 Nov 2017 11:13:06 EST //www.koonmotors.com/releases/2017/11/171120111306.htm //www.koonmotors.com/releases/2017/11/171106112236.htm Researchers studying a protein that causes a hereditary degenerative brain disease in humans have discovered that the human, mouse and hamster forms of the protein, which have nearly identical amino acid sequences, exhibit distinct three-dimensional structures at the atomic level. Mon, 06 Nov 2017 11:22:36 EST //www.koonmotors.com/releases/2017/11/171106112236.htm //www.koonmotors.com/releases/2017/10/171020160018.htm A team of scientists have described the synthetic genetic tool they built to quantitatively sense, measure and manipulate protein aggregation in live cells. This may open the door to greater understanding and treatment of a range of maladies from Alzheimer's to type II diabetes. Fri, 20 Oct 2017 16:00:18 EDT //www.koonmotors.com/releases/2017/10/171020160018.htm //www.koonmotors.com/releases/2017/09/170926105415.htm New research summarizes the efforts in disease surveillance and risk management of chronic wasting disease (CWD) in deer and shows that past management strategies such as selective culling, herd reduction, and hunter surveillance have had only limited effectiveness. The summary points towards new advice for optimal, cost-effective strategies in aggressive disease control. Tue, 26 Sep 2017 10:54:15 EDT //www.koonmotors.com/releases/2017/09/170926105415.htm //www.koonmotors.com/releases/2017/08/170829090956.htm A new kind of antibody targets a feature shared by proteins thought to cause the most damage in Alzheimer's disease, Parkinson's disease, and related conditions, creating potential for a unified treatment approach. Tue, 29 Aug 2017 09:09:56 EDT //www.koonmotors.com/releases/2017/08/170829090956.htm //www.koonmotors.com/releases/2017/07/170710091732.htm New research could offer hope to the thousands of, mainly young, people affected by the hereditary condition Neurofibromatosis 2 (NF2). In addition to NF2 disease there could be potential benefit for other cancers with the same mutations. Mon, 10 Jul 2017 09:17:32 EDT //www.koonmotors.com/releases/2017/07/170710091732.htm //www.koonmotors.com/releases/2017/06/170620093111.htm A team of scientists collaborated on a study of functional amyloids -protein aggregates with the typical amyloid structure that do not lead to disease but rather serve a dedicated biological function. Tue, 20 Jun 2017 09:31:11 EDT //www.koonmotors.com/releases/2017/06/170620093111.htm //www.koonmotors.com/releases/2017/05/170525100236.htm A molecular mechanism in the prion protein, a protein responsible for neurodegenerative diseases, has now been uncovered by researchers, which may explain why nerve cells degenerate in these disorders. The findings may one day lead to better therapies and treatments for these diseases Thu, 25 May 2017 10:02:36 EDT //www.koonmotors.com/releases/2017/05/170525100236.htm //www.koonmotors.com/releases/2017/02/170223202445.htm Researchers have discovered unique amyloid fibers used by the highly drug resistant Staphylococcus aureus bacterium (which causes MRSA). The findings could lead to new types of antibiotics with a novel mechanism of action for attacking bacterial toxins, they say. Thu, 23 Feb 2017 20:24:45 EST //www.koonmotors.com/releases/2017/02/170223202445.htm //www.koonmotors.com/releases/2016/12/161214151559.htm Fresh insights into infectious brain conditions help to explain why some people -- and animals -- are more at risk than others. Wed, 14 Dec 2016 15:15:59 EST //www.koonmotors.com/releases/2016/12/161214151559.htm //www.koonmotors.com/releases/2016/09/160930080857.htm Two caffeine-based chemical compounds have been developed that show promise in preventing the ravages of Parkinson’s disease. Parkinson’s disease attacks the nervous system, causing uncontrolled shakes, muscle stiffness, and slow, imprecise movement, chiefly in middle-aged and elderly people. It is caused by the loss of brain cells (neurons) that produce dopamine, an essential neurotransmitter that allows neurons to “talk” to each other. Fri, 30 Sep 2016 08:08:57 EDT //www.koonmotors.com/releases/2016/09/160930080857.htm //www.koonmotors.com/releases/2016/08/160829094020.htm 一个测试可以检测的帕金森病early stages of the illness has moved a step closer. Mon, 29 Aug 2016 09:40:20 EDT //www.koonmotors.com/releases/2016/08/160829094020.htm //www.koonmotors.com/releases/2016/08/160809095128.htm New experiments in mice now enable researchers to evaluate prion disease progression and potential therapeutic interventions in vivo, according to a new report. Tue, 09 Aug 2016 09:51:28 EDT //www.koonmotors.com/releases/2016/08/160809095128.htm //www.koonmotors.com/releases/2016/08/160808115849.htm 科学家们已经澄清细节理解the beneficial function of a type of protein normally associated with prion diseases of the brain, such as bovine spongiform encephalopathy (commonly known as mad cow disease) and its human counterpart, variant Creutzfeldt-Jakob disease. Mon, 08 Aug 2016 11:58:49 EDT //www.koonmotors.com/releases/2016/08/160808115849.htm //www.koonmotors.com/releases/2016/08/160808115626.htm When prion proteins mutate, they trigger mad cow and Creutzfeldt-Jakob disease. Although they are found in virtually every organism, the function of these proteins remained unclear. Researchers now demonstrate that prion proteins, coupled with a particular receptor, are responsible for nerve health. The discovery could yield novel treatments for chronic nerve diseases. Mon, 08 Aug 2016 11:56:26 EDT //www.koonmotors.com/releases/2016/08/160808115626.htm //www.koonmotors.com/releases/2016/07/160713100855.htm Researchers have developed a system capable of quickly screening millions of yeast cells to measure protein aggregates. Proteins regulate all of the processes that keep cells alive, but when misfolded they can clump into large aggregations, a phenomenon associated with diseases including Alzheimer's, Huntington's and Parkinson's. Wed, 13 Jul 2016 10:08:55 EDT //www.koonmotors.com/releases/2016/07/160713100855.htm //www.koonmotors.com/releases/2016/05/160526151738.htm Prion diseases are fatal and incurable neurodegenerative conditions of humans and animals. Yet, how prions kill nerve cells (or neurons) remains unclear. A new study describes a system in which to study the early assault by prions on brain cells of the infected host. Thu, 26 May 2016 15:17:38 EDT //www.koonmotors.com/releases/2016/05/160526151738.htm //www.koonmotors.com/releases/2016/04/160418161010.htm New research suggests a complex dance between actin filaments and aggregating proteins is key to the molecular machinery that forms and stores long-term memories. Mon, 18 Apr 2016 16:10:10 EDT //www.koonmotors.com/releases/2016/04/160418161010.htm //www.koonmotors.com/releases/2016/03/160307114250.htm A novel mechanism has been found that could protect the brain from damage due to stroke and a variety of neurodegenerative conditions, including sporadic Creutzfeldt-Jakob disease, Alzheimer’s disease, and Parkinson’s disease, report scientists. Mon, 07 Mar 2016 11:42:50 EST //www.koonmotors.com/releases/2016/03/160307114250.htm //www.koonmotors.com/releases/2016/01/160128151934.htm Immunotherapy to ameliorate neurodegeneration by targeting brain protein aggregates with antibodies is an area of intense investigation. A new study examines seemingly contradictory earlier results of targeting the prion protein and proposes a cautionary way forward to further test related therapeutic approaches. Thu, 28 Jan 2016 15:19:34 EST //www.koonmotors.com/releases/2016/01/160128151934.htm //www.koonmotors.com/releases/2016/01/160126111522.htm Up to now Alzheimer’s disease has not been recognized as transmissible. Now researchers have demonstrated Alzheimer-type pathology in brains of recipients of dura mater grafts who died later from Creutzfeldt-Jakob disease. Tue, 26 Jan 2016 11:15:22 EST //www.koonmotors.com/releases/2016/01/160126111522.htm //www.koonmotors.com/releases/2016/01/160106213743.htm The ALS-related protein TDP-43 takes the first steps toward pathologic aggregation as part of its normal function, according to a new study. The study supports the emerging idea that protein aggregation in neurologic disease may be an exaggeration of the normal functions of the aggregating proteins. Wed, 06 Jan 2016 21:37:43 EST //www.koonmotors.com/releases/2016/01/160106213743.htm //www.koonmotors.com/releases/2016/01/160105133128.htm In Parkinson's disease, the protein 'alpha-synuclein' aggregates within neurons of patients and appears to propagate across interconnected areas of the brain. How this happens remains largely unknown. It has been proposed that alpha-synuclein may behave like a 'prion.' However, recent findings reveal that pathology caused by alpha-synuclein does not necessarily involve prion-like seeding. Instead, it could be triggered by enhanced alpha-synuclein expression and trans-neuronal passage of monomeric and oligomeric forms of the protein. Tue, 05 Jan 2016 13:31:28 EST //www.koonmotors.com/releases/2016/01/160105133128.htm //www.koonmotors.com/releases/2015/12/151203135850.htm During the holidays, we often remember the past and create new memories. But, why do some memories fade away while others last forever? Scientists have identified a possible biochemical mechanism by which the specialized brain cells known as neurons create and maintain a long-term memory from a fleeting experience. Thu, 03 Dec 2015 13:58:50 EST //www.koonmotors.com/releases/2015/12/151203135850.htm //www.koonmotors.com/releases/2015/10/151014121103.htm Is brain size related to cognitive ability of humans? This question has captured the attention of scientists for more than a century. An international team of researchers provides no evidence for a causal role of brain size for IQ test performance. In a meta-analysis of data from more than 8000 participants, they show that associations between in vivo brain volume and IQ are small. Wed, 14 Oct 2015 12:11:03 EDT //www.koonmotors.com/releases/2015/10/151014121103.htm //www.koonmotors.com/releases/2015/09/150922104006.htm Prion diseases -- incurable, ultimately fatal, transmissible neurodegenerative disorders of mammals -- are believed to develop undetected in the brain over several years from infectious prion protein. In a new study, NIH scientists report they can detect infectious prion protein in mouse brains within a week of inoculation. Equally surprising, the protein was generated outside blood vessels in a place in the brain where scientists believe drug treatment could be targeted to prevent disease. Tue, 22 Sep 2015 10:40:06 EDT //www.koonmotors.com/releases/2015/09/150922104006.htm //www.koonmotors.com/releases/2015/08/150831163735.htm Multiple System Atrophy, a neurodegenerative disorder with similarities to Parkinson's disease, is caused by a newly discovered type of prion, according to two new research papers. Mon, 31 Aug 2015 16:37:35 EDT //www.koonmotors.com/releases/2015/08/150831163735.htm //www.koonmotors.com/releases/2015/08/150813104308.htm The discovery of antidepressant drugs led to the first biochemical hypothesis of depression, known as the monoamine hypothesis. However, this hypothesis does not seem to fully explain the complexity of human depression. Now a new study offers one more important key that may increase our understanding of the pathogenesis behind clinical depression and neurodegenerative disorders. Thu, 13 Aug 2015 10:43:08 EDT //www.koonmotors.com/releases/2015/08/150813104308.htm //www.koonmotors.com/releases/2015/08/150804103448.htm Diagnosis of deadly brain conditions could be helped by new research that shows how infectious proteins that cause the disease spread. Research reveals how the proteins -- called prions -- spread from the gut to the brain after a person or animal has eaten contaminated meat. Tue, 04 Aug 2015 10:34:48 EDT //www.koonmotors.com/releases/2015/08/150804103448.htm