//www.koonmotors.com/news/mind_brain/bipolar_disorder/ Bipolar Disorder News. Read the latest medical research on causes, symptoms and new treatments for bipolar disorder. en-us Wed, 13 Sep 2023 11:18:44 EDT Wed, 13 Sep 2023 11:18:44 EDT 60 //www.koonmotors.com/images/scidaily-logo-rss.png//www.koonmotors.com/news/mind_brain/bipolar_disorder/ For more science news, visit ScienceDaily. //www.koonmotors.com/releases/2023/08/230821113943.htm People who have recovered from a major depressive episode, when compared with individuals who have never experienced one, tend to spend more time processing negative information and less time processing positive information, putting them at risk for a relapse, according to new research. Mon, 21 Aug 2023 11:39:43 EDT //www.koonmotors.com/releases/2023/08/230821113943.htm //www.koonmotors.com/releases/2023/08/230802235456.htm Treatment with modern antidepressants may help prevent patients with bipolar disorder from relapsing into a depressive episode, according to an international clinical trial. The findings challenge current clinical practice guidelines and could change how bipolar depression is managed globally. Wed, 02 Aug 2023 23:54:56 EDT //www.koonmotors.com/releases/2023/08/230802235456.htm //www.koonmotors.com/releases/2022/12/221215104551.htm Diagnosing psychiatric disorders is challenging due to the lack of objective tests. Fortunately, genomic studies can reveal genes associated with increased risk of certain disorders. In a recent study, researchers from Japan investigated whether the genetic correlations between major psychiatric disorders differed among European and East Asian populations. They showed differences in how bipolar disorders are diagnosed by psychiatrists in the East and the West, which might affect the results of clinical trials. Thu, 15 Dec 2022 10:45:51 EST //www.koonmotors.com/releases/2022/12/221215104551.htm //www.koonmotors.com/releases/2022/05/220511085709.htm An analysis of 11 major psychiatric disorders offers new insight into why comorbidities are the norm when it comes to mental illness. The study suggests that while there is no single gene or set of genes underlying risk for all of them, subsets of disorders -- including bipolar disorder and schizophrenia; anorexia nervosa and obsessive-compulsive disorder; and major depression and anxiety --s hare a common genetic architecture. Wed, 11 May 2022 08:57:09 EDT //www.koonmotors.com/releases/2022/05/220511085709.htm //www.koonmotors.com/releases/2022/03/220328092055.htm A study that showed changes in the brain in those at risk of developing bipolar disorder raises new hopes about early intervention. Mon, 28 Mar 2022 09:20:55 EDT //www.koonmotors.com/releases/2022/03/220328092055.htm //www.koonmotors.com/releases/2022/03/220317143710.htm Researchers have identified a link suggesting that lithium could decrease the risk of developing dementia, which affects nearly one million people in the UK. Thu, 17 Mar 2022 14:37:10 EDT //www.koonmotors.com/releases/2022/03/220317143710.htm //www.koonmotors.com/releases/2022/03/220309090709.htm 在美国近600000名成年人进行分析ound people with bipolar disorder, schizophrenia or schizoaffective disorder had up to double the estimated cardiovascular risk levels than those without such illnesses, even at younger ages. The study focused on adults diagnosed with one of those three serious mental illnesses, who were not hospitalized or living in a mental health treatment center and estimated their 10-year and 30-year cardiovascular risk. Earlier identification and management of major cardiovascular risk factors -- including obesity, smoking, diabetes and high blood pressure -- in young adults with a serious mental illness may reduce risk of heart disease and improve outcomes, researchers said. Wed, 09 Mar 2022 09:07:09 EST //www.koonmotors.com/releases/2022/03/220309090709.htm //www.koonmotors.com/releases/2021/12/211223225442.htm Scientists investigating the DNA outside our genes - the 'dark genome' - have discovered recently evolved regions that code for proteins associated with schizophrenia and bipolar disorder. Thu, 23 Dec 2021 22:54:42 EST //www.koonmotors.com/releases/2021/12/211223225442.htm //www.koonmotors.com/releases/2021/11/211129212806.htm A new study finds that the prevalence of type 2 diabetes (T2D) is elevated in people with a psychiatric disorder compared with the general population. Mon, 29 Nov 2021 21:28:06 EST //www.koonmotors.com/releases/2021/11/211129212806.htm //www.koonmotors.com/releases/2021/11/211102093422.htm 双相情感障碍(BD)是一种使人衰弱的psychiatric disorder characterized by fluctuating periods of depression and mania. Researchers have long suspected that BD may be accompanied by abnormal structural and functional changes in the brain. Small cross-sectional brain imaging studies of people with BD have shown hints at those changes, but the ability to interpret data collected at a single timepoint is limited. Now, a multi-center longitudinal study shows aberrant changes over time in the brains of people with BD. Some changes were specifically associated with more episodes of mania. Tue, 02 Nov 2021 09:34:22 EDT //www.koonmotors.com/releases/2021/11/211102093422.htm //www.koonmotors.com/releases/2021/09/210923115615.htm Can specific dietary guidelines help people living with bipolar disorders better manage their health? Clinical trial results showed that a diet designed to alter levels of specific fatty acids consumed by participants may help patients have less variability in their mood. Thu, 23 Sep 2021 11:56:15 EDT //www.koonmotors.com/releases/2021/09/210923115615.htm //www.koonmotors.com/releases/2021/08/210805115451.htm Researchers have conducted a new trial to identify how an existing psychological therapy can be adapted to help people cope with and manage frequent bipolar mood swings. Thu, 05 Aug 2021 11:54:51 EDT //www.koonmotors.com/releases/2021/08/210805115451.htm //www.koonmotors.com/releases/2021/05/210511201118.htm New research suggests a link between psychosis and a genetic change that affects the brain's immune system. The study may impact the development of modern medicines for bipolar disorder or schizophrenia. Tue, 11 May 2021 20:11:18 EDT //www.koonmotors.com/releases/2021/05/210511201118.htm //www.koonmotors.com/releases/2021/04/210408112310.htm Worldwide, 1 in 4 people will suffer from a depressive episode in their lifetime. While current diagnosis and treatment approaches are largely trial and error, a breakthrough study sheds new light on the biological basis of mood disorders, and offers a promising blood test aimed at a precision medicine approach to treatment. Thu, 08 Apr 2021 11:23:10 EDT //www.koonmotors.com/releases/2021/04/210408112310.htm //www.koonmotors.com/releases/2021/03/210323150726.htm Psychiatric researchers have identified interactions between genes and sex that might partly explain how major psychiatric disorders affect males and females differently. Tue, 23 Mar 2021 15:07:26 EDT //www.koonmotors.com/releases/2021/03/210323150726.htm //www.koonmotors.com/releases/2021/03/210304145427.htm Cells called astrocytes derived from the induced pluripotent stem cells of patients with bipolar disorder offer suboptimal support for neuronal activity. This malfunction can be traced to an inflammation-promoting molecule called interleukin-6 (IL-6), which is secreted by astrocytes. The results highlight the potential role of astrocyte-mediated inflammatory signaling in the psychiatric disease, although further investigation is needed. Thu, 04 Mar 2021 14:54:27 EST //www.koonmotors.com/releases/2021/03/210304145427.htm //www.koonmotors.com/releases/2021/02/210208185115.htm A new study suggests that differences in the expression of gene transcripts - readouts copied from DNA that help maintain and build our cells - may hold the key to understanding how mental disorders with shared genetic risk factors result in different patterns of onset, symptoms, course of illness, and treatment responses. Mon, 08 Feb 2021 18:51:15 EST //www.koonmotors.com/releases/2021/02/210208185115.htm //www.koonmotors.com/releases/2020/11/201110133137.htm Relapse in people with bipolar disorder can be predicted accurately by their tendency towards having pessimistic beliefs, according to a new study. Tue, 10 Nov 2020 13:31:37 EST //www.koonmotors.com/releases/2020/11/201110133137.htm //www.koonmotors.com/releases/2020/10/201014140938.htm A review of 39 randomized clinical trials has found that combining the use medication with psychoeducational therapy is more effective at preventing a recurrence of illness in people with bipolar disorder than medication alone. Wed, 14 Oct 2020 14:09:38 EDT //www.koonmotors.com/releases/2020/10/201014140938.htm //www.koonmotors.com/releases/2020/08/200825110737.htm 研究人员已经确定了遗传风险因子for developing bipolar disorder and psychoses among people with depression. In the longer term, the results may contribute to ensuring the correct diagnosis is made earlier, so that the patients can receive the correct treatment as quickly as possible. Tue, 25 Aug 2020 11:07:37 EDT //www.koonmotors.com/releases/2020/08/200825110737.htm //www.koonmotors.com/releases/2020/07/200730132813.htm The number of adults in the United States who suffer from major depressive episodes at some point in their life is far higher than previously believed, a new study finds. Thu, 30 Jul 2020 13:28:13 EDT //www.koonmotors.com/releases/2020/07/200730132813.htm //www.koonmotors.com/releases/2020/02/200219124227.htm A sweeping new set of findings reveals previously unknown details explaining why some neurons in bipolar patients swing between being overly or under excited. The researchers used experimental and computational techniques to describe how variations in potassium and sodium currents in the brain cells of people with bipolar disorder may help to further explain why some patients respond to lithium and others do not. Wed, 19 Feb 2020 12:42:27 EST //www.koonmotors.com/releases/2020/02/200219124227.htm //www.koonmotors.com/releases/2020/02/200204112538.htm Researchers shed new light on the genetic relationship between three mood disorders associated with depression -- major depression and bipolar disorder types 1 and 2 -- in a new study. Tue, 04 Feb 2020 11:25:38 EST //www.koonmotors.com/releases/2020/02/200204112538.htm //www.koonmotors.com/releases/2020/01/200122122101.htm A study has shown few differences in the profiles of genes that influence cognition between people with schizophrenia, bipolar disorder and the general population. This surprising finding could provide new insights into therapies designed to improve cognition. Wed, 22 Jan 2020 12:21:01 EST //www.koonmotors.com/releases/2020/01/200122122101.htm //www.koonmotors.com/releases/2019/10/191029105618.htm Psychotic spectrum (PS) disorders are characterized by abnormalities in beliefs, perceptions and behavior, but how these disorders manifest themselves in earlier development stages is largely unknown. A new study reports differences in brain structure among youth with PS disorders relative to typically developing youth. Tue, 29 Oct 2019 10:56:18 EDT //www.koonmotors.com/releases/2019/10/191029105618.htm //www.koonmotors.com/releases/2019/08/190820081844.htm Brain abnormalities in people at familial risk of schizophrenia and bipolar disorder emerge in unique patterns, despite the symptom and genetic overlap of the disorders, according to a new study. Similarities between schizophrenia and bipolar disorder have led to the diagnoses being increasingly combined in studies of psychosis, but the findings highlight that risk for the disorders has distinct effects on the brain. Tue, 20 Aug 2019 08:18:44 EDT //www.koonmotors.com/releases/2019/08/190820081844.htm //www.koonmotors.com/releases/2019/07/190716095531.htm A researcher collaborated with the World Health Organization on the first study to seek input from people with common mental health issues on how their disorders are described in diagnostic guidelines. Tue, 16 Jul 2019 09:55:31 EDT //www.koonmotors.com/releases/2019/07/190716095531.htm //www.koonmotors.com/releases/2019/06/190624214055.htm Better care and more research into treatments for people experiencing a first manic episode are urgently needed, according to researchers. The study describes patchy and inconsistent care, widespread failure to detect bipolar disorder early enough, and a lack of guidance on how to treat people experiencing mania for the first time. Mon, 24 Jun 2019 21:40:55 EDT //www.koonmotors.com/releases/2019/06/190624214055.htm //www.koonmotors.com/releases/2019/06/190612084357.htm Patterns of brain activation during reward anticipation may help identify people most at risk for developing bipolar spectrum disorders (BPSD), according to a new study. Mania in people with BPSD is often accompanied by impulsivity, including impulsive responses to potential rewards. In the study, patterns of neural activation during a reward task predicted the severity of the mania symptom in young adults who have not yet developed the disorder. Wed, 12 Jun 2019 08:43:57 EDT //www.koonmotors.com/releases/2019/06/190612084357.htm //www.koonmotors.com/releases/2019/05/190522162718.htm People who have bipolar disorder may be more likely to later develop Parkinson's disease than people who do not have bipolar disorder, according at a new study. Wed, 22 May 2019 16:27:18 EDT //www.koonmotors.com/releases/2019/05/190522162718.htm //www.koonmotors.com/releases/2019/05/190513155626.htm Findings from a new study of large-scale systems in the brain could improve understanding of the symptoms and causes of bipolar disorder, schizophrenia, depression, and other mental illnesses. Researchers detail their investigation into brain network connectivity in patients with psychotic disorders. Mon, 13 May 2019 15:56:26 EDT //www.koonmotors.com/releases/2019/05/190513155626.htm //www.koonmotors.com/releases/2019/05/190503100829.htm A newly identified epigenetic hotspot for schizophrenia and bipolar disorder may give scientists a fresh path forward for devising more effective treatments and biomarker-based screening strategies. More than 100 million people worldwide have either schizophrenia or bipolar disorder, which are characterized by periods of hallucinations, delusions and irregular thought processes. They are both associated with overproduction of the neurotransmitter dopamine, a key regulator of reward-seeking behavior, emotional responses, learning and movement, among other functions. Fri, 03 May 2019 10:08:29 EDT //www.koonmotors.com/releases/2019/05/190503100829.htm //www.koonmotors.com/releases/2019/05/190501131357.htm In the largest study of its kind, involving more than 50,000 subjects in 14 countries, researchers at more than 200 collaborating institutions have identified 20 new genetic associations with one of the most prevalent and elusive mental illnesses of our time -- bipolar disorder. Wed, 01 May 2019 13:13:57 EDT //www.koonmotors.com/releases/2019/05/190501131357.htm //www.koonmotors.com/releases/2019/03/190321130300.htm African-Americans with severe depression are more likely to be misdiagnosed as having schizophrenia, according to a new study. Thu, 21 Mar 2019 13:03:00 EDT //www.koonmotors.com/releases/2019/03/190321130300.htm //www.koonmotors.com/releases/2019/01/190124115344.htm A form of rare genomic structural variation called copy number variants (CNVs) may be more closely associated with schizophrenia than bipolar disorder. Thu, 24 Jan 2019 11:53:44 EST //www.koonmotors.com/releases/2019/01/190124115344.htm //www.koonmotors.com/releases/2019/01/190115121108.htm A new study explored the impact of increasing a person's intake of vitamins B12, B6, and folic acid [vitamin B9] after studies in people with schizophrenia revealed that increased intake of these vitamins could decrease patients' levels of an amino acid called homocysteine and improve their symptoms. Tue, 15 Jan 2019 12:11:08 EST //www.koonmotors.com/releases/2019/01/190115121108.htm //www.koonmotors.com/releases/2018/10/181008083514.htm A pilot study has found that pregnant women who have suffered from depression or bipolar disorder (i.e. both mania and depression) recognize babies' faces and how babies laugh or cry, differently to healthy controls. This happens even if they are not currently experiencing depressive or manic symptoms and may represent an early risk-factor for children of these women, although the authors stress that research would be needed to confirm any long-term effects. Mon, 08 Oct 2018 08:35:14 EDT //www.koonmotors.com/releases/2018/10/181008083514.htm //www.koonmotors.com/releases/2018/10/181007084039.htm Data from a clinical trial has shown that how people respond to treatment for Bipolar Disorder may be influenced by their weight and the overall quality of their diet, including whether they are eating a diet high in foods thought to contribute to general inflammation. These are early results, but if replicated may mean that treatment of some mental health problems could benefit from the inclusion of dietary advice. Sun, 07 Oct 2018 08:40:39 EDT //www.koonmotors.com/releases/2018/10/181007084039.htm //www.koonmotors.com/releases/2018/09/180920115531.htm Although depression is one of the leading psychiatric disorders, its cause remains unclear. A recent study found that those affected by depressive disorder have a larger hypothalamus compared to their healthy counterparts. This could explain why many sufferers show increased levels of the stress hormone cortisol and are very often afflicted with periods of tension. Thu, 20 Sep 2018 11:55:31 EDT //www.koonmotors.com/releases/2018/09/180920115531.htm //www.koonmotors.com/releases/2018/09/180904093747.htm New research has found that neurons deep inside the brain could hold the key to accurately diagnosing bipolar disorder and depression. Tue, 04 Sep 2018 09:37:47 EDT //www.koonmotors.com/releases/2018/09/180904093747.htm //www.koonmotors.com/releases/2018/08/180828104002.htm Patients living with bipolar disorder and depression will soon be able to use a unique wearable sensor to safely monitor their lithium drug levels. Tue, 28 Aug 2018 10:40:02 EDT //www.koonmotors.com/releases/2018/08/180828104002.htm //www.koonmotors.com/releases/2018/08/180809112440.htm Can viruses trigger psychiatric disorders? A new study suggests yes. Accordingly, special disorders are associated with a high rate of infection of a specific herpesvirus. Thu, 09 Aug 2018 11:24:40 EDT //www.koonmotors.com/releases/2018/08/180809112440.htm //www.koonmotors.com/releases/2018/07/180723143024.htm Psychologists have devised a novel psychological intervention to address Anxiety in Bipolar Disorder (AIBD). Anxiety is common in Bipolar Disorder (BD) and associated with worse clinical outcomes including increased suicidality. Despite effective psychological treatments for anxiety, research into treating anxiety in BD is underdeveloped. Mon, 23 Jul 2018 14:30:24 EDT //www.koonmotors.com/releases/2018/07/180723143024.htm //www.koonmotors.com/releases/2018/07/180718082225.htm An analysis of more than 1,000 people with and without psychiatric disorders has shown that nitrates -- chemicals used to cure meats such as beef jerky, salami, hot dogs and other processed meat snacks -- may contribute to mania, an abnormal mood state. Mania is characterized by hyperactivity, euphoria and insomnia. Wed, 18 Jul 2018 08:22:25 EDT //www.koonmotors.com/releases/2018/07/180718082225.htm //www.koonmotors.com/releases/2018/06/180611133414.htm Mutations in the gene ANT1 may confer a risk for bipolar disorder through a complex interplay between serotonin and mitochondrial signaling in the brain. These two pathways have been separately implicated in bipolar disorder, but the link between levels of the neurotransmitter serotonin and mitochondrial dysfunction had not been established. Researchers now report that mitochondrial dysfunction affects the activity of serotonergic neurons in mice with mutations of ANT1. Mon, 11 Jun 2018 13:34:14 EDT //www.koonmotors.com/releases/2018/06/180611133414.htm //www.koonmotors.com/releases/2018/06/180608101921.htm During a depressive episode the ability of the brain to form new brain cells is reduced. Scientists examined how this affects the memory with a computational model. It was previously known that people in an acute depressive episode were less likely to remember current events. The computational model however suggests that older memories were affected as well. How long the memory deficits reach back depends on how long the depressive episode lasts. Fri, 08 Jun 2018 10:19:21 EDT //www.koonmotors.com/releases/2018/06/180608101921.htm //www.koonmotors.com/releases/2018/05/180524141652.htm The brain's ability to form new neural connections, called neuroplasticity, is crucial to recovery from some types of brain injury, but this process is hard to study and remains poorly understood. A new study of neural circuit repair in the retina shows that neurons can make new connections to the right types of photoreceptors to restore selective connectivity after an injury. Thu, 24 May 2018 14:16:52 EDT //www.koonmotors.com/releases/2018/05/180524141652.htm //www.koonmotors.com/releases/2018/04/180405120340.htm A blood test may have the potential to speed accurate diagnosis -- and proper treatment -- of bipolar disorder in children, new research suggests. Thu, 05 Apr 2018 12:03:40 EDT //www.koonmotors.com/releases/2018/04/180405120340.htm //www.koonmotors.com/releases/2018/02/180228131138.htm Individuals with bipolar disorder have the lowest risk of rehospitalization if treated with lithium, according to a new study. Long-acting injections of antipsychotics were also effective, reducing the risk of rehospitalization by 30 per cent compared with their oral counterparts. Wed, 28 Feb 2018 13:11:38 EST //www.koonmotors.com/releases/2018/02/180228131138.htm //www.koonmotors.com/releases/2018/02/180222125710.htm Recent studies suggest that ketamine, a widely used anesthetic agent, could offer a wholly new approach to treating severe depression -- producing an antidepressant response in hours rather than weeks. Experts weigh recent evidence on ketamine and related drugs for treating depression in two new published reviews. Thu, 22 Feb 2018 12:57:10 EST //www.koonmotors.com/releases/2018/02/180222125710.htm //www.koonmotors.com/releases/2018/01/180110112935.htm The most common subtypes of bipolar disorder, bipolar I and bipolar II, stem -- at least in part -- from different biological causes, according to a new study. Despite genetic overlap between the two subtypes, each subtype tended to cluster within families, suggesting a distinction between bipolar disorders I and II. Wed, 10 Jan 2018 11:29:35 EST //www.koonmotors.com/releases/2018/01/180110112935.htm //www.koonmotors.com/releases/2017/12/171215121058.htm Nearly six million Americans have bipolar disorder, and most have probably wondered why. After more than a decade of studying over 1,100 of them in-depth, a team of scientists has an answer -- or rather, seven answers. Fri, 15 Dec 2017 12:10:58 EST //www.koonmotors.com/releases/2017/12/171215121058.htm //www.koonmotors.com/releases/2017/12/171213130504.htm Researchers believe that a significant number of people diagnosed with schizophrenia or bipolar disorder may actually have a treatable immune system condition. A new research study could have a significant impact on the millions diagnosed with schizophrenia or bipolar disorder, including many homeless. Wed, 13 Dec 2017 13:05:04 EST //www.koonmotors.com/releases/2017/12/171213130504.htm //www.koonmotors.com/releases/2017/12/171212125412.htm Bipolar disorder may involve accelerated epigenetic aging, which could explain why persons with the disorder are more likely to have -- and die from -- age-related diseases, according to researchers. Tue, 12 Dec 2017 12:54:12 EST //www.koonmotors.com/releases/2017/12/171212125412.htm //www.koonmotors.com/releases/2017/12/171204091813.htm Genetic susceptibility to bipolar disorder can increase the risk for suicide attempt, but only among those who also have experienced traumatic stress, reports a new study. Mon, 04 Dec 2017 09:18:13 EST //www.koonmotors.com/releases/2017/12/171204091813.htm //www.koonmotors.com/releases/2017/11/171130214932.htm Cannabis use in youth is linked to bipolar symptoms in young adults, finds new research. Thu, 30 Nov 2017 21:49:32 EST //www.koonmotors.com/releases/2017/11/171130214932.htm //www.koonmotors.com/releases/2017/11/171121095403.htm A simple 15-minute electrocardiogram could help a physician determine whether a patient has major depression or bipolar disorder, a groundbreaking new study reports. Tue, 21 Nov 2017 09:54:03 EST //www.koonmotors.com/releases/2017/11/171121095403.htm //www.koonmotors.com/releases/2017/11/171108151928.htm Genes linked to schizophrenia in psychiatric patients suffering from bipolar disorder are the reason why such patients don't respond to the "gold standard" treatment for bipolar -- the drug lithium -- according to international research. Wed, 08 Nov 2017 15:19:28 EST //www.koonmotors.com/releases/2017/11/171108151928.htm //www.koonmotors.com/releases/2017/10/171016132756.htm Computerized brain training can result in improved cognitive skills in individuals with bipolar disorder, researchers have discovered for the first time. Mon, 16 Oct 2017 13:27:56 EDT //www.koonmotors.com/releases/2017/10/171016132756.htm //www.koonmotors.com/releases/2017/10/171011120339.htm A new study of young people experiencing a first episode of psychosis reports elevations in the brain chemicals glutamate and glycine. Wed, 11 Oct 2017 12:03:39 EDT //www.koonmotors.com/releases/2017/10/171011120339.htm