//www.koonmotors.com/news/mind_brain/autism/ Autism symptoms and new approaches to treatment. Read current research on autism including early diagnosis of autism spectrum disorders, genetic factors and more. en-us Fri, 08 Sep 2023 20:48:37 EDT Fri, 08 Sep 2023 20:48:37 EDT 60 //www.koonmotors.com/images/scidaily-logo-rss.png//www.koonmotors.com/news/mind_brain/autism/ For more science news, visit ScienceDaily. //www.koonmotors.com/releases/2023/08/230817163922.htm The largest ever study of the genetics of the brain -- encompassing some 36,000 brain scans -- has identified more than 4,000 genetic variants linked to brain structure. Thu, 17 Aug 2023 16:39:22 EDT //www.koonmotors.com/releases/2023/08/230817163922.htm //www.koonmotors.com/releases/2023/08/230816160006.htm Researcher discovers possible link of mitochondrial function to the development of schizophrenia. Wed, 16 Aug 2023 16:00:06 EDT //www.koonmotors.com/releases/2023/08/230816160006.htm //www.koonmotors.com/releases/2023/08/230810110412.htm Two distinct neurodevelopmental abnormalities that arise just weeks after the start of brain development have been associated with the emergence of autism spectrum disorder, according to a new study in which researchers developed brain organoids from the stem cells of boys diagnosed with the disorder. Thu, 10 Aug 2023 11:04:12 EDT //www.koonmotors.com/releases/2023/08/230810110412.htm //www.koonmotors.com/releases/2023/07/230718105725.htm Researchers have developed a fluorescent sensor that may be useful for understanding how cells recognize themselves versus other cells when making connections in the brain. Specifically, their sensor can be used to visualize not only connections between cells, but also the disassociation of these interactions. Tue, 18 Jul 2023 10:57:25 EDT //www.koonmotors.com/releases/2023/07/230718105725.htm //www.koonmotors.com/releases/2023/07/230713141945.htm Study suggests modulating the activity of certain neurons could be an effective approach to restoring circuit function. Thu, 13 Jul 2023 14:19:45 EDT //www.koonmotors.com/releases/2023/07/230713141945.htm //www.koonmotors.com/releases/2023/07/230706160116.htm Researchers showed that consuming THC while pregnant could potentially affect development of the fetus and lead to life-long health impacts for offspring. Thu, 06 Jul 2023 16:01:16 EDT //www.koonmotors.com/releases/2023/07/230706160116.htm //www.koonmotors.com/releases/2023/07/230705143010.htm An antisense therapy restores production of the protein FMRP in cell samples taken from patients with fragile X syndrome. This breakthrough was possible because of the novel findings, also presented in the study, that aberrant alternative splicing of messenger RNA (mRNA) plays a principal role in fragile X syndrome, the most common form of inherited intellectual disability and the most frequent single-gene cause of autism. Wed, 05 Jul 2023 14:30:10 EDT //www.koonmotors.com/releases/2023/07/230705143010.htm //www.koonmotors.com/releases/2023/05/230523123734.htm Research has revealed features of early human brain development are mimicked in the brains of marsupials. Tue, 23 May 2023 12:37:34 EDT //www.koonmotors.com/releases/2023/05/230523123734.htm //www.koonmotors.com/releases/2023/05/230504111851.htm 研究人员发现disru Foxp2基因的突变pt the formation of synapses in the brain's striatum, which plays important roles in the control of movement, in mice. A new study sheds light on how Foxp2 controls speech production. Thu, 04 May 2023 11:18:51 EDT //www.koonmotors.com/releases/2023/05/230504111851.htm //www.koonmotors.com/releases/2023/04/230426210436.htm Researchers have identified the mechanism for why and how one brain region differs in size between male and female rats. The study found that immune system cells in the brains of females consume and digest neurons to sculp a region of the brain during development and that later affects behavioral preferences in adulthood. Wed, 26 Apr 2023 21:04:36 EDT //www.koonmotors.com/releases/2023/04/230426210436.htm //www.koonmotors.com/releases/2023/04/230425111134.htm 帮你妈妈做煎饼时three...riding your bike without training wheels...your first romantic kiss: How do we retain vivid memories of long-ago events? Tue, 25 Apr 2023 11:11:34 EDT //www.koonmotors.com/releases/2023/04/230425111134.htm //www.koonmotors.com/releases/2023/04/230420141754.htm Researchers have found that an extra copy of a gene in Down syndrome patients causes improper development of neurons in mice. Thu, 20 Apr 2023 14:17:54 EDT //www.koonmotors.com/releases/2023/04/230420141754.htm //www.koonmotors.com/releases/2023/03/230310143656.htm To help provide an insight into the possible ASD-cardiometabolic diseases link, researchers conducted a systematic review and meta-analysis. The results indicated that ASD was associated with greater risks of developing diabetes overall, including both type 1 and type 2 diabetes. Fri, 10 Mar 2023 14:36:56 EST //www.koonmotors.com/releases/2023/03/230310143656.htm //www.koonmotors.com/releases/2023/03/230307144334.htm New research that may eventually enable far earlier autism diagnoses shows that typically developing infants perceive audio-video synchrony better than high-risk for autism infants. Tue, 07 Mar 2023 14:43:34 EST //www.koonmotors.com/releases/2023/03/230307144334.htm //www.koonmotors.com/releases/2023/02/230228075739.htm A 'biocomputer' powered by human brain cells could be developed within our lifetime, according to researchers who expect such technology to exponentially expand the capabilities of modern computing and create novel fields of study. Tue, 28 Feb 2023 07:57:39 EST //www.koonmotors.com/releases/2023/02/230228075739.htm //www.koonmotors.com/releases/2023/02/230224135044.htm Adverse childhood experiences in mothers can affect their children's mental and physical health, as researchers report. The study found that maltreatment during a mother's childhood is associated with a higher risk of health problems such as asthma, autism, and depression in the next generation. Early intervention to support affected mothers might help to counter this effect. Fri, 24 Feb 2023 13:50:44 EST //www.koonmotors.com/releases/2023/02/230224135044.htm //www.koonmotors.com/releases/2023/02/230221113129.htm Engineering researchers are successfully using a robot to help keep children with learning disabilities focused on their work. Tue, 21 Feb 2023 11:31:29 EST //www.koonmotors.com/releases/2023/02/230221113129.htm //www.koonmotors.com/releases/2023/02/230216083406.htm In Fragile X syndrome, sensory signals from the outside world are integrated differently, causing them to be underrepresented by cortical pyramidal neurons in the brain, according to a new study. Thu, 16 Feb 2023 08:34:06 EST //www.koonmotors.com/releases/2023/02/230216083406.htm //www.koonmotors.com/releases/2023/02/230215143606.htm Researchers used computational modeling to uncover mutations in the human genome that likely influenced the evolution of human cognition. This groundbreaking research in human genomics could lead to a better understanding of human health and the discovery of novel treatments for complex brain disorders. The study is to be published in Science Advances. Wed, 15 Feb 2023 14:36:06 EST //www.koonmotors.com/releases/2023/02/230215143606.htm //www.koonmotors.com/releases/2023/02/230214153934.htm Brain-wave data collected during a hearing test routinely given to newborns could help clinicians spot neurodevelopmental disorders such as autism in early infancy, according to a new study. Tue, 14 Feb 2023 15:39:34 EST //www.koonmotors.com/releases/2023/02/230214153934.htm //www.koonmotors.com/releases/2023/02/230213201102.htm 行为障碍是孤独症患者中一样sociated with a multitude of genetic alterations. Scientists have now found another molecular cause for this condition. The transcription factor MYT1L normally protects the molecular identity of nerve cells. If it is genetically switched off in human nerve cells or in mice, the functional changes and symptoms typical of autism occur. A drug that blocks sodium channels in the cell membrane can reverse the consequences of MYT1L failure and alleviate the functional and behavioral abnormalities in mice. Mon, 13 Feb 2023 20:11:02 EST //www.koonmotors.com/releases/2023/02/230213201102.htm //www.koonmotors.com/releases/2023/02/230213201032.htm Feeling a sense of purpose has a significant impact on adolescents' emotional well-being. Mon, 13 Feb 2023 20:10:32 EST //www.koonmotors.com/releases/2023/02/230213201032.htm //www.koonmotors.com/releases/2023/02/230208125050.htm Toddlers' level of attention to 'motherese' speech can be used as a biomarker for autism spectrum disorder (ASD), according to new research. To measure it, scientists developed a new eye-tracking test, which can accurately identify toddlers with a subtype of ASD. Wed, 08 Feb 2023 12:50:50 EST //www.koonmotors.com/releases/2023/02/230208125050.htm //www.koonmotors.com/releases/2023/01/230126124401.htm Scientists have created a new collection of month-by-month infant brain atlas (IBA) that capture fine details of the early developing brain across both space and time. Thu, 26 Jan 2023 12:44:01 EST //www.koonmotors.com/releases/2023/01/230126124401.htm //www.koonmotors.com/releases/2023/01/230120130916.htm Neuroscientists find two distinct cell populations in the striatum are affected differently by Huntington's disease. They believe neurodegeneration of one of these populations leads to motor impairments, while damage to the other population, located in a structure called the striosome, may account for the mood disorders that are often see in the early stages of the disease. Fri, 20 Jan 2023 13:09:16 EST //www.koonmotors.com/releases/2023/01/230120130916.htm //www.koonmotors.com/releases/2023/01/230116112600.htm On Blue Monday -- supposedly the gloomiest day of the year -- a study shows adults with high levels of attention-deficit hyperactivity disorder (ADHD) symptoms are more likely to experience anxiety and depression than adults with high levels of autistic traits. Mon, 16 Jan 2023 11:26:00 EST //www.koonmotors.com/releases/2023/01/230116112600.htm //www.koonmotors.com/releases/2022/12/221226151543.htm Females, on average, are better than males at putting themselves in others' shoes and imagining what the other person is thinking or feeling, suggests a new study of over 300,000 people in 57 countries. Mon, 26 Dec 2022 15:15:43 EST //www.koonmotors.com/releases/2022/12/221226151543.htm //www.koonmotors.com/releases/2022/12/221220113100.htm Antidepressant use during pregnancy may combine with inflammation to heighten the risk of lifelong neurodevelopmental changes in babies' brains, new research suggests. Tue, 20 Dec 2022 11:31:00 EST //www.koonmotors.com/releases/2022/12/221220113100.htm //www.koonmotors.com/releases/2022/12/221220113015.htm A virtual reality game offers an objective assessment of attention deficit disorders and may lead to an improved therapeutic approach. Tue, 20 Dec 2022 11:30:15 EST //www.koonmotors.com/releases/2022/12/221220113015.htm //www.koonmotors.com/releases/2022/12/221207163032.htm Although people are generally predisposed to perceive interactions to be social even in unlikely contexts, they don't always agree on exactly which information is social, according to a new study. The findings show that much of the brain responds more strongly to information that is interpreted as social versus non-social. Wed, 07 Dec 2022 16:30:32 EST //www.koonmotors.com/releases/2022/12/221207163032.htm //www.koonmotors.com/releases/2022/11/221130151535.htm Researchers have discovered that removal of cilia from the brain's striatum region impaired time perception and judgment, revealing possible new therapeutic targets for mental and neurological conditions including schizophrenia, Parkinson's and Huntington's diseases, autism spectrum disorder, and Tourette syndrome. Wed, 30 Nov 2022 15:15:35 EST //www.koonmotors.com/releases/2022/11/221130151535.htm //www.koonmotors.com/releases/2022/11/221130151524.htm Researchers have discovered a specific genetic variant in SCN1A, the most common genetic epilepsy, that leads to an earlier onset of epilepsy, with clinical features distinct from other epilepsies. The researchers also identified a potentially effective treatment strategy. Wed, 30 Nov 2022 15:15:24 EST //www.koonmotors.com/releases/2022/11/221130151524.htm //www.koonmotors.com/releases/2022/11/221123193629.htm A new animal study points to a gene that is important for the earliest development of basic social behaviors. The work also suggests that exposure to certain drugs and environmental risk factors during embryonic development can cause changes to this gene, leading to alterations in social behavior that are similar to those found in individuals who have autism. Wed, 23 Nov 2022 19:36:29 EST //www.koonmotors.com/releases/2022/11/221123193629.htm //www.koonmotors.com/releases/2022/11/221121130748.htm Scientists looking to understand the fundamental brain mechanisms of autism spectrum disorder have found that a gene mutation known to be associated with the disorder causes an overstimulation of brain cells far greater than that seen in neuronal cells without the mutation. The study, spanning seven years, employed some of the most advanced approaches available in the scientific toolbox, including growing human brain cells from stem cells and transplanting them into mouse brains. Mon, 21 Nov 2022 13:07:48 EST //www.koonmotors.com/releases/2022/11/221121130748.htm //www.koonmotors.com/releases/2022/11/221116133831.htm Researchers have successfully identified differences in gene activity in the brains of people with attention deficit hyperactivity disorder (ADHD). The study found that individuals diagnosed with ADHD had differences in genes that code for known chemicals that brain cells use to communicate. The results show how genomic differences might contribute to symptoms. Wed, 16 Nov 2022 13:38:31 EST //www.koonmotors.com/releases/2022/11/221116133831.htm //www.koonmotors.com/releases/2022/11/221115114125.htm Part of understanding the underlying causes of autism spectrum disorder relies on figuring out which cells' signaling patterns in the brain are disrupted, and when during nervous system development the disruption occurs. New research findings in mouse models of one genetic risk for autism support the idea that loss of a specific gene interferes with cells in the brain whose role is to inhibit signaling. Tue, 15 Nov 2022 11:41:25 EST //www.koonmotors.com/releases/2022/11/221115114125.htm //www.koonmotors.com/releases/2022/11/221109151925.htm Using an innovative technology that enables imaging of two individuals during live and natural conditions, researchers have identified specific brain areas in the dorsal parietal region of the brain associated with the social symptomatology of autism. Wed, 09 Nov 2022 15:19:25 EST //www.koonmotors.com/releases/2022/11/221109151925.htm //www.koonmotors.com/releases/2022/11/221107103151.htm People with autism are often portrayed in popular media as experiencing difficulty processing highly stimulating or overly loud environments. While this is certainly true for many, there can be a wide diversity in the ways people comprehend the information they perceive from all senses. New research shows that adding assessments focused on sensory integration into the regular autism assessment process can yield new information for patients and their care teams to help guide therapeutic activities. Mon, 07 Nov 2022 10:31:51 EST //www.koonmotors.com/releases/2022/11/221107103151.htm //www.koonmotors.com/releases/2022/11/221102123611.htm Engaging infants with a song provides a ready-made means for supporting social development and interaction, according to a new study. Wed, 02 Nov 2022 12:36:11 EDT //www.koonmotors.com/releases/2022/11/221102123611.htm //www.koonmotors.com/releases/2022/11/221102123603.htm 在自闭症综合througho时大脑的变化ut the cerebral cortex rather than just particular areas thought to affect social behavior and language, according to a new study that significantly refines scientists' understanding of how autism spectrum disorder (ASD) progresses at the molecular level. Wed, 02 Nov 2022 12:36:03 EDT //www.koonmotors.com/releases/2022/11/221102123603.htm //www.koonmotors.com/releases/2022/11/221101124248.htm Findings from a new study are providing further insight into the neurobiological basis of autism spectrum disorders and pointing to possible treatments. Tue, 01 Nov 2022 12:42:48 EDT //www.koonmotors.com/releases/2022/11/221101124248.htm //www.koonmotors.com/releases/2022/11/221101111538.htm Researchers have catalogued thousands of sites in the brain where RNA is modified throughout the human lifespan in a process known as adenosine-to-inosine (A-to-I) editing, offering important new avenues for understanding the cellular and molecular mechanisms of brain development and how they factor into both health and disease. Tue, 01 Nov 2022 11:15:38 EDT //www.koonmotors.com/releases/2022/11/221101111538.htm //www.koonmotors.com/releases/2022/10/221027132714.htm Actors may suppress their core sense of self when acting, as they immerse themselves in a new role, according to a new study. Thu, 27 Oct 2022 13:27:14 EDT //www.koonmotors.com/releases/2022/10/221027132714.htm //www.koonmotors.com/releases/2022/10/221020130319.htm Scientists have identified a long-sought gene-encoded protein that enables the brain to communicate a broad range of signals across gaps between neurons, known as synapses. Thu, 20 Oct 2022 13:03:19 EDT //www.koonmotors.com/releases/2022/10/221020130319.htm //www.koonmotors.com/releases/2022/10/221018131133.htm A team led by researchers has developed a powerful computational tool for understanding brain health and disease, providing an enhanced way of characterizing the activity of the brain during sleep. Tue, 18 Oct 2022 13:11:33 EDT //www.koonmotors.com/releases/2022/10/221018131133.htm //www.koonmotors.com/releases/2022/10/221006092319.htm The seed-sized organoids -- which are grown in the lab from human cells -- contained an array of neural and other cell types found in the cerebral cortex, the outermost layer of the brain involved in language, emotion, reasoning, and other high-level mental processes. They are providing insights into the brain and uncovering differences that may contribute to autism in some people. Thu, 06 Oct 2022 09:23:19 EDT //www.koonmotors.com/releases/2022/10/221006092319.htm //www.koonmotors.com/releases/2022/09/220923090951.htm A study has found an association, in children aged 9-12, between exposure to air pollutants in the womb and during the first 8.5 years of life and alterations in white matter structural connectivity in the brain. The greater the child's exposure before age 5, the greater the brain structure alteration observed in preadolescence. Fri, 23 Sep 2022 09:09:51 EDT //www.koonmotors.com/releases/2022/09/220923090951.htm //www.koonmotors.com/releases/2022/09/220922124416.htm 研究人员开发出一种新颖的荧光传感器to detect and monitor levels of the neuropeptide oxytocin, also known as the 'happy hormone.' The OT sensor facilitated the successful measurement of OT dynamics in the brains of living animals and may serve as a foundation for the development of therapeutics for the treatment of neurological disorders. Thu, 22 Sep 2022 12:44:16 EDT //www.koonmotors.com/releases/2022/09/220922124416.htm //www.koonmotors.com/releases/2022/09/220922103132.htm Scientists have shown that defects in the protein CAPRIN1 are the cause of various neurological impairments. Thu, 22 Sep 2022 10:31:32 EDT //www.koonmotors.com/releases/2022/09/220922103132.htm //www.koonmotors.com/releases/2022/09/220907192544.htm Infections in pregnant women have been linked to an increased risk of neurodevelopmental conditions, such as autism, in the child later in life. But it does not seem to be the infections themselves that cause autism, researchers show in a new study. Wed, 07 Sep 2022 19:25:44 EDT //www.koonmotors.com/releases/2022/09/220907192544.htm //www.koonmotors.com/releases/2022/09/220907093422.htm Results of a small but unique research study suggest that low-dose ketamine is generally safe, well-tolerated and effective to treat clinical symptoms in children diagnosed with ADNP syndrome (also known as Helsmoortel-VanDerAa syndrome), a rare neurodevelopmental disorder caused by mutations in the activity dependent neuroprotective protein (ADNP) gene. Wed, 07 Sep 2022 09:34:22 EDT //www.koonmotors.com/releases/2022/09/220907093422.htm //www.koonmotors.com/releases/2022/09/220901200635.htm Scientists hypothesize that circadian rhythm disruption is a psychopathology factor shared by a broad range of mental illnesses and that research into its molecular foundation could be key to unlocking better therapies and treatments. Thu, 01 Sep 2022 20:06:35 EDT //www.koonmotors.com/releases/2022/09/220901200635.htm //www.koonmotors.com/releases/2022/09/220901135752.htm A new study suggests that therapeutic interventions to treat neurodevelopmental disorders may be more effective if done during the early stages of brain development. Thu, 01 Sep 2022 13:57:52 EDT //www.koonmotors.com/releases/2022/09/220901135752.htm //www.koonmotors.com/releases/2022/08/220830145154.htm Star-shaped cells called astrocytes may bear the brunt of the responsibility for exacerbating the symptoms of some neurodevelopmental disorders. Scientists have now identified a molecule produced by astrocytes that interferes with normal neuron development in Rett, fragile X and Down syndromes. Blocking the molecule reduces the signs of disease in mice brains. Tue, 30 Aug 2022 14:51:54 EDT //www.koonmotors.com/releases/2022/08/220830145154.htm //www.koonmotors.com/releases/2022/08/220830131627.htm Young people living with a genetic alteration that increases the risk of psychiatric disorders have markedly different brain activity during sleep, a new study shows. Tue, 30 Aug 2022 13:16:27 EDT //www.koonmotors.com/releases/2022/08/220830131627.htm //www.koonmotors.com/releases/2022/08/220826150446.htm About 50% of all mothers of children with autism spectrum disorder (ASD) had elevated levels of depressive symptoms over 18 months, while rates were much lower (6% to 13.6%) for mothers with neurotypical children in the same period, researchers report. Fri, 26 Aug 2022 15:04:46 EDT //www.koonmotors.com/releases/2022/08/220826150446.htm //www.koonmotors.com/releases/2022/08/220823162739.htm A baby's cry is a form of communication used to attract attention from adult caregivers, and every baby cries in a similar but distinct way. Researchers have studied the vocal behavior of baby mice, called pups, to determine how the age of the father affects the pups' vocal communication and body weight development. Their study will help them better understand vocal development in human babies. Tue, 23 Aug 2022 16:27:39 EDT //www.koonmotors.com/releases/2022/08/220823162739.htm //www.koonmotors.com/releases/2022/08/220822091047.htm Measuring how the eyes' pupils change in response to light -- known as the pupillary light reflex -- could potentially be used to screen for autism in young children, according to a new study. Mon, 22 Aug 2022 09:10:47 EDT //www.koonmotors.com/releases/2022/08/220822091047.htm //www.koonmotors.com/releases/2022/08/220818141808.htm Scientists used high-resolution MRI data to create a valuable new resource for the study of human brain development at key moments in utero and after birth. Thu, 18 Aug 2022 14:18:08 EDT //www.koonmotors.com/releases/2022/08/220818141808.htm //www.koonmotors.com/releases/2022/08/220818122341.htm Researchers used data from the SPARK (Simons Powering Autism Research) research cohort, which was created to advance our understanding of the complex genetics of autism and includes genetic data from nearly 43,000 people with autism. The findings show differences in genetic influences among people all along the autism spectrum. Thu, 18 Aug 2022 12:23:41 EDT //www.koonmotors.com/releases/2022/08/220818122341.htm