Alzheimer's Research News -- ScienceDaily //www.koonmotors.com/news/mind_brain/alzheimer's/ Read the latest research on Alzheimer's disease. Learn about Alzheimer's symptoms such as memory loss and senile dementia. Find out about Alzheimer's stages, causes and new treatments. en-us Sun, 10 Sep 2023 20:48:20 EDT Sun, 10 Sep 2023 20:48:20 EDT 60 Alzheimer's Research News -- ScienceDaily //www.koonmotors.com/images/scidaily-logo-rss.png//www.koonmotors.com/news/mind_brain/alzheimer's/ 更多的science news, visit ScienceDaily. Exercise-induced hormone irisin may reduce Alzheimer's disease plaque and tangle pathology in the brain //www.koonmotors.com/releases/2023/09/230908125947.htm Medical researchers have used a 3D human neural cell culture model to show that the exercise-induced muscle hormone, irisin, reduces the level of amyloid beta deposits associated with Alzheimer's disease. Fri, 08 Sep 2023 12:59:47 EDT //www.koonmotors.com/releases/2023/09/230908125947.htm Specialized T cells in the brain slow progression of Alzheimer's disease //www.koonmotors.com/releases/2023/09/230907130430.htm Scientists found that a subset of CD8+ T cells in the brain lessens the activation of microglia and limits disease pathology in a model of Alzheimer's disease. Thu, 07 Sep 2023 13:04:30 EDT //www.koonmotors.com/releases/2023/09/230907130430.htm Phase I clinical trial shows treatment designed to clear senescent cells in Alzheimer's disease is safe //www.koonmotors.com/releases/2023/09/230907130337.htm Scientists are reporting results from a Phase I trial in an area of promising research for Alzheimer's disease -- cellular senescence. Thu, 07 Sep 2023 13:03:37 EDT //www.koonmotors.com/releases/2023/09/230907130337.htm 睡眠不足会损害大脑如何 //www.koonmotors.com/releases/2023/09/230906143429.htm Not only does a lack of sleep make you feel awful, research has shown it impairs the brain. What's more, sleep loss over long periods can even increase risk for Alzheimer's and other neurological diseases. Researchers want to understand how sleep deprivation causes this harm. In a new study, a team working with mice has identified a protective protein whose level declines with sleep deprivation, leading to neuronal death. Wed, 06 Sep 2023 14:34:29 EDT //www.koonmotors.com/releases/2023/09/230906143429.htm Researchers identify new gene mutation that alters Alzheimer's disease risk //www.koonmotors.com/releases/2023/09/230906115607.htm A groundbreaking study has shed new light on the genetic underpinnings of Alzheimer's disease. Wed, 06 Sep 2023 11:56:07 EDT //www.koonmotors.com/releases/2023/09/230906115607.htm Researchers to study Alzheimer's disease in marmosets //www.koonmotors.com/releases/2023/09/230906112412.htm Neuroscientists created the first non-human primate model of hereditary Alzheimer's in marmosets to accelerate the pace of drug discovery and rebuild the foundation for future translational studies. Wed, 06 Sep 2023 11:24:12 EDT //www.koonmotors.com/releases/2023/09/230906112412.htm New cause of Alzheimer's, vascular dementia //www.koonmotors.com/releases/2023/09/230905155717.htm 研究人员已经发现了一种新途径的细胞death in Alzheimer's disease and vascular dementia. The study reveals for the first time that a form of cell death known as ferroptosis -- caused by a buildup of iron in cells -- destroys microglia cells in cases of Alzheimer's and vascular dementia. Tue, 05 Sep 2023 15:57:17 EDT //www.koonmotors.com/releases/2023/09/230905155717.htm Radiologists must monitor novel Alzheimer's treatment side effect //www.koonmotors.com/releases/2023/08/230831142812.htm A new article examines the use of monoclonal antibody therapies for treating Alzheimer disease and alerts physicians to be on the lookout for a potential side effect: amyloid-related imaging abnormalities. Thu, 31 Aug 2023 14:28:12 EDT //www.koonmotors.com/releases/2023/08/230831142812.htm New blood test gives very high accuracy to screen for Alzheimer's disease //www.koonmotors.com/releases/2023/08/230831121807.htm A new blood test called p-tau217 shows promise as an Alzheimer's disease biomarker, and when used in a two-step workflow very high accuracy to either identify or exclude brain amyloidosis, the most important and earliest pathology. Thu, 31 Aug 2023 12:18:07 EDT //www.koonmotors.com/releases/2023/08/230831121807.htm New blood test detects a key indicator of Parkinson's disease //www.koonmotors.com/releases/2023/08/230830151742.htm Researchers have developed a blood test that detects Parkinson's disease, potentially establishing a way to help diagnose the condition before nervous system damage worsens. A new blood-based diagnostic test would be a major advancement for Parkinson's disease, which afflicts 10 million people worldwide and is the second-most common neurodegenerative disease after Alzheimer's. Wed, 30 Aug 2023 15:17:42 EDT //www.koonmotors.com/releases/2023/08/230830151742.htm Educational attainment protects against a genetic risk factor for Alzheimer's disease //www.koonmotors.com/releases/2023/08/230830133603.htm 一项新的研究进一步说明时to risk of Alzheimer's disease, even genetically determined forms of the disease, genetics is only one piece of the puzzle. Researchers investigated the influence of genetics and educational attainment on cognitive decline by studying data from 675 people who carry a mutation that predisposes them to early onset Alzheimer's disease. Carriers of this mutation -- known as PSEN1 E280A -- have a median age of 49 for onset of dementia. The team found that among carriers who also carried a second mutation that puts them at heightened risk -- APOE e4 -- had an accelerated age of onset of cognitive decline. Among carriers who had an APOE e2 mutation -- known to be protective -- age of onset was delayed. The team also assessed the effect of educational attainment on cognitive function among PSEN1 E280A mutation carriers, including those who carried different APOE genotypes. They found that higher educational attainment -- that is, more years of education -- was associated with preserved cognitive ability particularly for those at highest genetic risk. Wed, 30 Aug 2023 13:36:03 EDT //www.koonmotors.com/releases/2023/08/230830133603.htm Discoveries on memory mechanisms could unlock new therapies for Alzheimer's and other brain diseases //www.koonmotors.com/releases/2023/08/230830131956.htm Scientists have made a 'paradigm shifting' discovery on the mechanisms required for learning and memory that could lead to new therapies for Alzheimer's disease and potentially Down syndrome. Wed, 30 Aug 2023 13:19:56 EDT //www.koonmotors.com/releases/2023/08/230830131956.htm A 'mini-brain' traces the link between concussion and Alzheimer's disease //www.koonmotors.com/releases/2023/08/230829125919.htm Damage associated with Alzheimer's disease begins within hours after a concussion according to results from research that uses a 'mini-brain' lab on a chip device. Tue, 29 Aug 2023 12:59:19 EDT //www.koonmotors.com/releases/2023/08/230829125919.htm Molecule reduces inflammation in Alzheimer's models //www.koonmotors.com/releases/2023/08/230829125813.htm A potential new Alzheimer's drug represses the harmful inflammatory response of the brain's immune cells, reducing disease pathology, preserving neurons and improving cognition in preclinical tests. Tue, 29 Aug 2023 12:58:13 EDT //www.koonmotors.com/releases/2023/08/230829125813.htm Half as many AF patients dying of heart attacks and strokes in the UK now //www.koonmotors.com/releases/2023/08/230825122031.htm Patients living with one of the UK's most common heart rhythm conditions are 50% less likely to die from a heart attack or stroke than they were at the start of the millennium, analysis of 70,000 newly diagnosed AF patients' health records has shown. Fri, 25 Aug 2023 12:20:31 EDT //www.koonmotors.com/releases/2023/08/230825122031.htm New human cell-based 3D model reveals insights into how immune cells contribute to Alzheimer's disease //www.koonmotors.com/releases/2023/08/230825122006.htm In the new study, the team used the model to demonstrate that as Alzheimer's pathology accumulates in the brain, specific types of immune cells called CT8+ T Cells surge into the brain and amplify the destruction caused by neuroinflammation. Fri, 25 Aug 2023 12:20:06 EDT //www.koonmotors.com/releases/2023/08/230825122006.htm When proteins get stuck at solid: unlocking the secrets to brain diseases //www.koonmotors.com/releases/2023/08/230824003818.htm Biomedical engineers have developed sophisticated optical techniques to monitor at close range the process by which protein aggregates form during liquid-to-liquid transition. This can lead to solid condensates which can trigger a process that forms neural plaques, that can cause Alzheimer's and other diseases. Thu, 24 Aug 2023 00:38:18 EDT //www.koonmotors.com/releases/2023/08/230824003818.htm A fitness tracker for brain health: How a headband can identify early signs of Alzheimer's disease in your sleep //www.koonmotors.com/releases/2023/08/230823122623.htm Researchers make progress in developing a digital biomarker that detects early signs of Alzheimer's disease in brainwave patterns using a simple 'wearable' headband at night. Wed, 23 Aug 2023 12:26:23 EDT //www.koonmotors.com/releases/2023/08/230823122623.htm Neuroscientists create new resource to improve Alzheimer's disease research models //www.koonmotors.com/releases/2023/08/230822151729.htm A new study uses more genetically diverse mouse models to study the accumulation and spread of abnormal tau protein deposits in the brain -- a known sign of Alzheimer's disease and several other neurodegenerative diseases. Tue, 22 Aug 2023 15:17:29 EDT //www.koonmotors.com/releases/2023/08/230822151729.htm Intermittent fasting improves Alzheimer's pathology, study shows //www.koonmotors.com/releases/2023/08/230821153213.htm New results suggest that intermittent fasting could be an effective treatment approach for Alzheimer's disease. Mice fed on a time-restricted schedule had better memory and less accumulation of amyloid proteins in the brain compared to controls. Mon, 21 Aug 2023 15:32:13 EDT //www.koonmotors.com/releases/2023/08/230821153213.htm 'Viral relicts' in the genome could fuel neurodegeneration //www.koonmotors.com/releases/2023/08/230821114333.htm Genetic remnants of viruses that are naturally present in the human genome could affect the development of neurodegenerative diseases. Researchers come to this conclusion on the basis of studies on cell cultures. Mon, 21 Aug 2023 11:43:33 EDT //www.koonmotors.com/releases/2023/08/230821114333.htm Platelets can replicate the benefits of exercise in the brain //www.koonmotors.com/releases/2023/08/230817164030.htm 研究人员已经发现了一个特定的注射blood factor can replicate the benefits of exercise in the brain. They've discovered that platelets secrete a protein, exerkine CXCL4/Platelet factor 4 or PF4, that rejuvenates neurons in aged mice in a similar way to physical exercise. This protein, which is released from platelets after exercise, results in regenerative and cognitive improvements when injected into aged mice. Thu, 17 Aug 2023 16:40:30 EDT //www.koonmotors.com/releases/2023/08/230817164030.htm Neuroscientists successfully test theory that forgetting is actually a form of learning //www.koonmotors.com/releases/2023/08/230817163935.htm Neuroscientists report the first results from experimental tests designed to explore the idea that 'forgetting' might not be a bad thing, and that it may represent a form of learning -- and outline results that support their core idea. Seemingly lost memories can be retrieved and updated by environmental cues, which means this research has implications for a range of diseases such as Alzheimer's. Thu, 17 Aug 2023 16:39:35 EDT //www.koonmotors.com/releases/2023/08/230817163935.htm Several vaccines associated with reduced risk of Alzheimer's disease in adults 65 and older //www.koonmotors.com/releases/2023/08/230816170628.htm Prior vaccination against tetanus and diphtheria, with or without pertussis (Tdap/Td); herpes zoster (HZ), better known as shingles; and pneumococcus are all associated with a reduced risk for developing Alzheimer's disease, according to new research. Wed, 16 Aug 2023 17:06:28 EDT //www.koonmotors.com/releases/2023/08/230816170628.htm Can AI help hospitals spot patients in need of extra non-medical assistance? //www.koonmotors.com/releases/2023/08/230814135416.htm Needs related to housing, transportation, food, social support and more can be identified through AI/ML techniques, study of medical record notes from patients with dementia shows. Mon, 14 Aug 2023 13:54:16 EDT //www.koonmotors.com/releases/2023/08/230814135416.htm New concussion headset shows when it's likely safe to return to play //www.koonmotors.com/releases/2023/08/230811172143.htm A new digital headset designed to measure alterations in brain function could change decisions about how quickly an athlete is ready to return to play after a concussion. In an evaluation of the device, researchers found it revealed brain changes even in athletes whose concussion symptoms had gone away, suggesting they could be playing too soon. Fri, 11 Aug 2023 17:21:43 EDT //www.koonmotors.com/releases/2023/08/230811172143.htm A therapeutic target for Alzheimer's disease discovered //www.koonmotors.com/releases/2023/08/230810110325.htm Scientists have succeeded in reversing certain cognitive manifestations associated with Alzheimer's disease in an animal model of the disease. Thu, 10 Aug 2023 11:03:25 EDT //www.koonmotors.com/releases/2023/08/230810110325.htm Long-term use of certain acid reflux drugs linked to higher risk of dementia //www.koonmotors.com/releases/2023/08/230809164727.htm People who take acid reflux medications called proton pump inhibitors for four-and-a-half years or more may have a higher risk of dementia compared to people who do not take these medications, according to new research. This study does not prove that acid reflux drugs cause dementia; it only shows an association. Wed, 09 Aug 2023 16:47:27 EDT //www.koonmotors.com/releases/2023/08/230809164727.htm Stem cell therapy rescues symptoms of Alzheimer's disease //www.koonmotors.com/releases/2023/08/230809164724.htm 有前途的临床结果表明造血tem cell therapy was effective in rescuing memory loss, neuroinflammation and beta amyloid build-up in a mouse model of Alzheimer's disease. Wed, 09 Aug 2023 16:47:24 EDT //www.koonmotors.com/releases/2023/08/230809164724.htm Alzheimer's gene associated with increased fertility in Amazonian women //www.koonmotors.com/releases/2023/08/230809164641.htm Previous research has revealed that a certain allele increases the risk for a variety of diseases in aging populations, specifically Alzheimer's and cardiovascular disease. And yet, despite its negative effects, this allele remains prevalent in approximately 20 percent of the human population. In a quest to determine how this negative allele is surviving natural selection, a group of researchers have discovered that the allele is associated with increased fertility in women. Wed, 09 Aug 2023 16:46:41 EDT //www.koonmotors.com/releases/2023/08/230809164641.htm A new ally in fighting brain diseases: Our very own skull //www.koonmotors.com/releases/2023/08/230809130628.htm Alzheimer's, stroke, multiple sclerosis and other neurological diseases cause severe damage due to neuroinflammation mediated by immune cells. Managing this inflammation poses a significant medical challenge because the brain is protected by the skull and additional surrounding membranes that make the brain less accessible for treatment approaches. Scientists had previously discovered pathways going from the bone marrow of the skull towards the brain, allowing immune cell movement. Now, new research revealed that cells in the skull's bone marrow are unique in their composition and in their disease response. These findings offer new possibilities for the diagnosis and treatment of neurological diseases and revolutionize brain health monitoring in the future with non-invasive skull imaging. Wed, 09 Aug 2023 13:06:28 EDT //www.koonmotors.com/releases/2023/08/230809130628.htm Tau-PET : Future of Alzheimer's patients //www.koonmotors.com/releases/2023/08/230809125914.htm Alzheimer's disease, one of the most common neurodegenerative diseases, leads to progressive loss of memory and autonomy. It is characterized by the accumulation of neurotoxic proteins in the brain, namely amyloid plaques and tau tangles. Due to the silent development of pathology over decades, very early diagnosis is of utmost importance to be able to take action as early as possible in the disease process. Wed, 09 Aug 2023 12:59:14 EDT //www.koonmotors.com/releases/2023/08/230809125914.htm Key cause of restricted blood flow to the brain in vascular dementia //www.koonmotors.com/releases/2023/08/230807152144.htm Researchers have uncovered a potential route to developing the first ever drug treatments for vascular dementia that directly target a cause of the condition. The research has shed light on how high blood pressure causes changes to arteries in the brain, a process that leads to the devastating condition. Mon, 07 Aug 2023 15:21:44 EDT //www.koonmotors.com/releases/2023/08/230807152144.htm Unraveling Alzheimer's catalysts //www.koonmotors.com/releases/2023/08/230807121947.htm Researchers have achieved a significant breakthrough by elucidating the structure of amyloid beta bound to glycolipids on the surface of nerve cells. This finding shed light on the critical role of abnormal amyloid beta fibril formation, a major contributor to Alzheimer's disease, and holds promise for innovative advancements in medicine and pharmacy. Mon, 07 Aug 2023 12:19:47 EDT //www.koonmotors.com/releases/2023/08/230807121947.htm Researchers propose a data-driven strategy to stratify risk of progression from mild cognitive impairment to Alzheimer's disease //www.koonmotors.com/releases/2023/08/230804123659.htm The projected cost of caring for millions of individuals who have Alzheimer's disease (AD) worldwide will exceed a $1 trillion in a few years. In addition to the enormous health burden, patients and their caregivers experience financial, physical and psychological strain. A theory regarding repeated drug failure in AD is that patients undergoing experimental therapies are selected too late in the disease process. Therefore, it is important to identify patients at a high risk of progression to AD in early stages of the disease. To help identify persons who could benefit from early interventions, researchers from Boston University have developed a deep learning framework that can stratify individuals with mild cognitive impairment (MCI) based on their risk of advancing to AD. Fri, 04 Aug 2023 12:36:59 EDT //www.koonmotors.com/releases/2023/08/230804123659.htm Insulin-like hormones critical for brain plasticity //www.koonmotors.com/releases/2023/08/230803213817.htm Research has identified a mechanism through which insulin-like growth factors facilitate brain plasticity. The insulin super-family of hormones, including insulin, insulin-like growth factor 1 (IGF1), and insulin-like growth factor 2 (IGF2), play a crucial role not only in regulating blood sugar, metabolism, and growth, but also in healthy brain development and function, including learning and memory. These hormones can enter the brain through the bloodstream from the liver or can be synthesized directly in neurons and glial cells within the brain. They bind to receptors, including the IGF1-Receptor, activating signals that modulate neuron growth and activity. Disruption of this signaling pathway is involved in cognitive decline and diseases such as Alzheimer's. Thu, 03 Aug 2023 21:38:17 EDT //www.koonmotors.com/releases/2023/08/230803213817.htm Potential new tool for early identification of dementia risk //www.koonmotors.com/releases/2023/08/230803125601.htm By analyzing data from nearly 13,000 subjects who participated in a long-term aging study, researchers found that an interviewer's rating of a cognitively healthy person's memory successfully predicted the likelihood of developing dementia over a 15-year period. Thu, 03 Aug 2023 12:56:01 EDT //www.koonmotors.com/releases/2023/08/230803125601.htm How immunity contributes to aging and neurodegeneration //www.koonmotors.com/releases/2023/08/230802132023.htm Researchers have found that a specific immune signaling pathway drives ageing-related inflammation and neurodegeneration. The work can help us understand the mechanisms behind ageing-associated impairment and disease. Wed, 02 Aug 2023 13:20:23 EDT //www.koonmotors.com/releases/2023/08/230802132023.htm Minds & eyes: Study shows dementia more common in older adults with vision issues //www.koonmotors.com/releases/2023/08/230801172009.htm In a sample of nearly 3,000 older adults who took vision tests and cognitive tests during home visits, the risk of dementia was much higher among those with eyesight problems -- including those who weren't able to see well even when they were wearing their usual eyeglasses or contact lenses. Tue, 01 Aug 2023 17:20:09 EDT //www.koonmotors.com/releases/2023/08/230801172009.htm Study raises possibility of immunotherapy treatment for ALS //www.koonmotors.com/releases/2023/08/230801152848.htm New research reveals a type of monoclonal antibody already tested in certain forms of cancer may be a promising treatment in stopping the progression of amyotrophic lateral sclerosis, or ALS, a fatal neurodegenerative disease. Tue, 01 Aug 2023 15:28:48 EDT //www.koonmotors.com/releases/2023/08/230801152848.htm 成功的香味:简单的香味公关方法oduces major memory boost //www.koonmotors.com/releases/2023/08/230801131700.htm When a fragrance wafted through the bedrooms of older adults for two hours every night for six months, memories skyrocketed. Participants in this study reaped a 226% increase in cognitive capacity compared to the control group. The researchers say the finding transforms the long-known tie between smell and memory into an easy, non-invasive technique for strengthening memory and potentially deterring dementia. Tue, 01 Aug 2023 13:17:00 EDT //www.koonmotors.com/releases/2023/08/230801131700.htm This protein may predict mild cognitive impairment years before symptoms //www.koonmotors.com/releases/2023/07/230731151542.htm 长期的结果,联邦政府资助的研究cognitively healthy adults -- most with a family history of Alzheimer's disease -- have added to evidence that low spinal fluid levels of a protein linked to learning and memory in mice may serve as an early predictor of mild cognitive impairment (MCI) years before symptoms appear. Mon, 31 Jul 2023 15:15:42 EDT //www.koonmotors.com/releases/2023/07/230731151542.htm Researchers identify 'clear changes' in aging brain using novel techniques //www.koonmotors.com/releases/2023/07/230731110711.htm Researchers investigating brain activity in older people say the coordination between neuronal activity and the brain's oxygenation is altered. Non-invasive recording of the function of these neurovascular units in living humans has never been done before, but has now been achieved by using several measurement techniques coupled with novel analysis methods. The results promise a relatively simple and non-invasive method for assessing the state of the brain in healthy aging, and in neurodegenerative disorders such as Alzheimer's disease. Mon, 31 Jul 2023 11:07:11 EDT //www.koonmotors.com/releases/2023/07/230731110711.htm Enhanced light sensitivity may contribute to Alzheimer's 'sundowning,' disease progression //www.koonmotors.com/releases/2023/07/230728113414.htm New Alzheimer's research suggests that enhanced light sensitivity may contribute to 'sundowning' -- the worsening of symptoms late in the day -- and spur sleep disruptions that contribute to the disease's progression. Fri, 28 Jul 2023 11:34:14 EDT //www.koonmotors.com/releases/2023/07/230728113414.htm Tau-regulating protein identified as a promising target for developing Alzheimer's disease treatment //www.koonmotors.com/releases/2023/07/230727144230.htm A gene encoding a protein linked to tau production -- tripartite motif protein 11 (TRIM11) -- was found to suppress deterioration in small animal models of neurodegenerative diseases similar to Alzheimer's disease (AD), while improving cognitive and motor abilities, according to new research. Thu, 27 Jul 2023 14:42:30 EDT //www.koonmotors.com/releases/2023/07/230727144230.htm People with increased genetic risk of Alzheimer's may lose sense of smell first //www.koonmotors.com/releases/2023/07/230726171240.htm People who carry the gene variant associated with the strongest risk for Alzheimer's disease may lose their ability to detect odors earlier than people who do not carry the gene variant, which may be an early sign of future memory and thinking problems. The gene variant associated with this increased risk of Alzheimer's is called APOE e4. Wed, 26 Jul 2023 17:12:40 EDT //www.koonmotors.com/releases/2023/07/230726171240.htm Scientists may have discovered mechanism behind cognitive decline in aging //www.koonmotors.com/releases/2023/07/230725171914.htm Scientists have discovered what they believe to be the central mechanism behind cognitive decline associated with normal aging. Tue, 25 Jul 2023 17:19:14 EDT //www.koonmotors.com/releases/2023/07/230725171914.htm New study reveals why defense against brain corrosion declines in people with Alzheimer's disease //www.koonmotors.com/releases/2023/07/230724122745.htm A new study hascrevealed that the progression of Alzheimer's disease (AD) can be slowed by suppressing a specific protein in the brain that causes corrosion. Mon, 24 Jul 2023 12:27:45 EDT //www.koonmotors.com/releases/2023/07/230724122745.htm Dementia becomes an emergency 1.4 million times a year //www.koonmotors.com/releases/2023/07/230724122530.htm More than 1.4 million times a year, people with Alzheimer's disease and other forms of dementia end up in emergency care, a new study shows, accounting for nearly 7% of all emergency visits for any reason by people over age 65. Compared with their peers who don't have dementia, these patients have twice the rate of seeking emergency care after an accident or a behavioral or mental health crisis. Mon, 24 Jul 2023 12:25:30 EDT //www.koonmotors.com/releases/2023/07/230724122530.htm Bodybuilding supplement may help stave off Alzheimer's //www.koonmotors.com/releases/2023/07/230722004622.htm The secret to protecting your memory may be a staple of a bodybuilder's diet. Researchers recently discovered that a muscle-building supplement called beta-hydroxy beta-methylbutyrate, also called HMB, may help protect memory, reduce plaques and ultimately help prevent the progression of Alzheimer's disease. Sat, 22 Jul 2023 00:46:22 EDT //www.koonmotors.com/releases/2023/07/230722004622.htm Volunteering in late life may protect the brain against cognitive decline and dementia //www.koonmotors.com/releases/2023/07/230720124958.htm Volunteering in late life is associated with better cognitive function -- specifically, better executive function and episodic memory. Thu, 20 Jul 2023 12:49:58 EDT //www.koonmotors.com/releases/2023/07/230720124958.htm Majority of older adults with cognitive impairment still drive //www.koonmotors.com/releases/2023/07/230720124934.htm The majority of older adults with cognitive impairment are still driving, despite concerns raised by caregivers and others, a study finds. Researchers say it's best for caregivers to start conversations surrounding driving earlier while the care recipient is able to understand and actively participate in the discussion. Thu, 20 Jul 2023 12:49:34 EDT //www.koonmotors.com/releases/2023/07/230720124934.htm Espresso can prevent Alzheimer's protein clumping in lab tests //www.koonmotors.com/releases/2023/07/230719112644.htm Whether enjoyed on its own or mixed into a latte, Americano or even a martini, espresso provides an ultra-concentrated jolt of caffeine to coffee lovers. But it might do more than just wake you up. Research now shows that, in preliminary in vitro laboratory tests, espresso compounds can inhibit tau protein aggregation -- a process that is believed to be involved in the onset of Alzheimer's disease. Wed, 19 Jul 2023 11:26:44 EDT //www.koonmotors.com/releases/2023/07/230719112644.htm Lewy body disease can be detected before symptoms //www.koonmotors.com/releases/2023/07/230718164245.htm Lewy body disease is the second most common neurodegenerative disease after Alzheimer's disease. A research group has now shown that the disease can be detected before symptoms appear, using a spinal fluid test. Researchers also demonstrate that reduced sense of smell is strongly linked to Lewy body disease even before other clear symptoms have developed. Tue, 18 Jul 2023 16:42:45 EDT //www.koonmotors.com/releases/2023/07/230718164245.htm New study shows anti-inflammatory drugs as a promising target for Alzheimer's disease //www.koonmotors.com/releases/2023/07/230717115837.htm A recent study centers around the idea that various anti-inflammatory drugs could be effective treatments for Alzheimer's disease. This study focused on a protein known as p38. Many labs have been working with this protein as a potential target for drug development to treat Alzheimer's disease and other conditions with neuroinflammatory dysfunction. Mon, 17 Jul 2023 11:58:37 EDT //www.koonmotors.com/releases/2023/07/230717115837.htm Third Alzheimer's drug represents 'opening chapter in new era' //www.koonmotors.com/releases/2023/07/230717115824.htm With yet a third new Alzheimer's drug expected to be approved by the Food and Drug Administration (FDA), the field is beginning to show progress in the fight to slow the disease. Mon, 17 Jul 2023 11:58:24 EDT //www.koonmotors.com/releases/2023/07/230717115824.htm Tau-based biomarker tracks Alzheimer's progression //www.koonmotors.com/releases/2023/07/230713141940.htm Researchers have discovered a biomarker for Alzheimer's disease in the cerebrospinal fluid known as MTBR-tau243 can be used to track the progression of the disease and could speed drug development. Thu, 13 Jul 2023 14:19:40 EDT //www.koonmotors.com/releases/2023/07/230713141940.htm Social isolation linked to lower brain volume //www.koonmotors.com/releases/2023/07/230712165229.htm Older people who have little social contact with others may be more likely to have loss of overall brain volume, and in areas of the brain affected by dementia, than people with more frequent social contact, according to a new study. Wed, 12 Jul 2023 16:52:29 EDT //www.koonmotors.com/releases/2023/07/230712165229.htm Why people who have Down's Syndrome age prematurely //www.koonmotors.com/releases/2023/07/230712124740.htm An overdosed gene on chromosome 21 causes people with Down's Syndrome to age faster than the general population. Wed, 12 Jul 2023 12:47:40 EDT //www.koonmotors.com/releases/2023/07/230712124740.htm Key improvements to Parkinson's disease cell therapies //www.koonmotors.com/releases/2023/07/230712124631.htm Researchers have demonstrated that a transplant surgical procedure (called 'needle trauma') triggers a profound immune response and causes the death of most grafted dopamine neurons. They also found that co-transplantation of neuronal cell therapy with host regulatory T cells resulted in effective suppression of needle trauma and significant improvement in the survival and recovery of grafts. These findings suggest a path for the 'realistic' use of cell therapy to treat neurodegenerative disorders. Wed, 12 Jul 2023 12:46:31 EDT //www.koonmotors.com/releases/2023/07/230712124631.htm