//www.koonmotors.com/news/health_medicine/viruses/ Virology News. Read current research on the virus structure, specific viruses (H5N1 flu, West Nile virus, HIV and more) and responses. en-us Sat, 09 Sep 2023 20:47:35 EDT Sat, 09 Sep 2023 20:47:35 EDT 60 //www.koonmotors.com/images/scidaily-logo-rss.png//www.koonmotors.com/news/health_medicine/viruses/ For more science news, visit ScienceDaily. //www.koonmotors.com/releases/2023/09/230907130332.htm By adding synergistic self-adjuvanting properties to Covid-19 RNA vaccines, researchers showed they could significantly boost the immune response generated in mice. Thu, 07 Sep 2023 13:03:32 EDT //www.koonmotors.com/releases/2023/09/230907130332.htm //www.koonmotors.com/releases/2023/09/230907105827.htm Herpes is not only unpleasant but it can, in some cases, also have dangerous complications and life-threatening consequences. A research team has now introduced a completely new approach for treating herpes. Their method is based on the inhibition of an enzyme that is needed for the release of newly formed virus particles from infected cells. Thu, 07 Sep 2023 10:58:27 EDT //www.koonmotors.com/releases/2023/09/230907105827.htm //www.koonmotors.com/releases/2023/09/230905125043.htm 每年,呼吸道合胞体病毒(RSV)use countless respiratory infections worldwide. For infants, young children and people with preexisting conditions, the virus can be life-threatening. The team has explored ways to reduce the risk of infection. Their findings show that -- when used correctly -- alcohol-based hand sanitizers and commercially available surface disinfectants provide good protection against transmission of the virus via surfaces. Tue, 05 Sep 2023 12:50:43 EDT //www.koonmotors.com/releases/2023/09/230905125043.htm //www.koonmotors.com/releases/2023/09/230905124955.htm A new study has shown that a subtype of avian flu virus, endemic in poultry farms in China, is undergoing mutational changes, which could increase the risk of the disease being passed on to humans. Tue, 05 Sep 2023 12:49:55 EDT //www.koonmotors.com/releases/2023/09/230905124955.htm //www.koonmotors.com/releases/2023/09/230905124929.htm 一项新的国际研究表明mpox(以前known as monkeypox) infections to be less severe among those who are vaccinated or had a previous infection in 2022, underlining the importance and effectiveness of vaccination. Tue, 05 Sep 2023 12:49:29 EDT //www.koonmotors.com/releases/2023/09/230905124929.htm //www.koonmotors.com/releases/2023/08/230831164228.htm Researchers have discovered some new and surprising ways that viral RNA and influenza virus are detected by human lung cells, which has potential implications for treating people affected by such viruses. Thu, 31 Aug 2023 16:42:28 EDT //www.koonmotors.com/releases/2023/08/230831164228.htm //www.koonmotors.com/releases/2023/08/230831121749.htm Researchers have developed a method for forecasting the short-term progression of an epidemic using extremely limited amounts of data. Thu, 31 Aug 2023 12:17:49 EDT //www.koonmotors.com/releases/2023/08/230831121749.htm //www.koonmotors.com/releases/2023/08/230830131950.htm Australian researchers have found an existing blood cancer drug can kill 'silent' HIV cells and delay reinfections -- a significant pre-clinical discovery that could lead to a future cure for the disease. Wed, 30 Aug 2023 13:19:50 EDT //www.koonmotors.com/releases/2023/08/230830131950.htm //www.koonmotors.com/releases/2023/08/230830131708.htm Nanofitins, which are derived from a protein in an archaeal microorganism found in hot springs -- successfully neutralized SARS-CoV-2 in mice and were well-tolerated. When inhaled by the rodents, the engineered nanofitins, which inhibit the virus by binding to its spike proteins, were observed to quickly reach the lungs in high doses both preventing and clearing early infections, researchers report. Wed, 30 Aug 2023 13:17:08 EDT //www.koonmotors.com/releases/2023/08/230830131708.htm //www.koonmotors.com/releases/2023/08/230829130023.htm A team of researchers has developed an innovative patient triage platform powered by artificial intelligence (AI) that the researchers say is capable of predicting patient disease severity and length of hospitalization during a viral outbreak. Tue, 29 Aug 2023 13:00:23 EDT //www.koonmotors.com/releases/2023/08/230829130023.htm //www.koonmotors.com/releases/2023/08/230822151743.htm Scientists have discovered a potential target for gastric cancers associated with Epstein-Barr Virus. Tue, 22 Aug 2023 15:17:43 EDT //www.koonmotors.com/releases/2023/08/230822151743.htm //www.koonmotors.com/releases/2023/08/230821114333.htm Genetic remnants of viruses that are naturally present in the human genome could affect the development of neurodegenerative diseases. Researchers come to this conclusion on the basis of studies on cell cultures. Mon, 21 Aug 2023 11:43:33 EDT //www.koonmotors.com/releases/2023/08/230821114333.htm //www.koonmotors.com/releases/2023/08/230817164016.htm A single injection of a novel CRISPR gene-editing treatment safely and efficiently removes SIV -- a virus related to the AIDS-causing agent HIV -- from the genomes of non-human primates, scientists now report. The groundbreaking work complements previous experiments as the basis for the first-ever clinical trial of an HIV gene-editing technology in human patients, which was authorized by the Food and Drug Administration (FDA) in 2022. Thu, 17 Aug 2023 16:40:16 EDT //www.koonmotors.com/releases/2023/08/230817164016.htm //www.koonmotors.com/releases/2023/08/230817163908.htm Scientists found that immune cells present in individuals long before influenza infection predict whether the illness is symptomatic. Thu, 17 Aug 2023 16:39:08 EDT //www.koonmotors.com/releases/2023/08/230817163908.htm //www.koonmotors.com/releases/2023/08/230816170628.htm Prior vaccination against tetanus and diphtheria, with or without pertussis (Tdap/Td); herpes zoster (HZ), better known as shingles; and pneumococcus are all associated with a reduced risk for developing Alzheimer's disease, according to new research. Wed, 16 Aug 2023 17:06:28 EDT //www.koonmotors.com/releases/2023/08/230816170628.htm //www.koonmotors.com/releases/2023/08/230816114227.htm Researchers have found that molecules in vegetables like broccoli or cauliflower help to maintain a healthy barrier in the lung and ease infection. Wed, 16 Aug 2023 11:42:27 EDT //www.koonmotors.com/releases/2023/08/230816114227.htm //www.koonmotors.com/releases/2023/08/230816114136.htm Teeth could be capable of preserving antibodies for hundreds of years, allowing scientists to investigate the history of infectious human diseases, a new study has found. Wed, 16 Aug 2023 11:41:36 EDT //www.koonmotors.com/releases/2023/08/230816114136.htm //www.koonmotors.com/releases/2023/08/230816114121.htm A new method allows large quantities of muscle stem cells to be safely obtained in cell culture. This provides a potential for treating patients with muscle diseases -- and for those who would like to eat meat, but don't want to kill animals. Wed, 16 Aug 2023 11:41:21 EDT //www.koonmotors.com/releases/2023/08/230816114121.htm //www.koonmotors.com/releases/2023/08/230814174537.htm Equipping cancer-infecting, or oncolytic, viruses with tumor-inhibiting genetic cargo stimulates the immune system and helps immunotherapy to shrink or completely clear aggressive tumors in mice, according to a new study. The results pave the way for clinical trials combining oncolytic viruses with immunotherapy. Mon, 14 Aug 2023 17:45:37 EDT //www.koonmotors.com/releases/2023/08/230814174537.htm //www.koonmotors.com/releases/2023/08/230814122326.htm Unexpected new insights into how COVID-19 infects cells help explain why coronaviruses are so good at jumping from species to species and will help scientists better predict how COVID-19 will evolve. Mon, 14 Aug 2023 12:23:26 EDT //www.koonmotors.com/releases/2023/08/230814122326.htm //www.koonmotors.com/releases/2023/08/230814122315.htm A form of gene therapy currently used to treat Parkinson's disease may dramatically reduce alcohol use among chronic heavy drinkers, researchers have found. Mon, 14 Aug 2023 12:23:15 EDT //www.koonmotors.com/releases/2023/08/230814122315.htm //www.koonmotors.com/releases/2023/08/230811115448.htm Researchers have created a panel of genetically diverse mice that accurately model the highly variable human response to SARS-CoV-2 infection. The team uncovered differences in the innate immune and regulated proinflammatory responses, the timing and strength of which are associated with disease severity. Fri, 11 Aug 2023 11:54:48 EDT //www.koonmotors.com/releases/2023/08/230811115448.htm //www.koonmotors.com/releases/2023/08/230811115433.htm An experimental malaria vaccine appears safe and promotes an immune response in African infants, one of the groups most vulnerable to severe malaria disease. There is currently only one malaria vaccine, 'RTS,S' that is approved by the World Health Organization and offers partial disease protection. However, in the results of the early-stage phase Ib trial, researchers find that targeting RH5 -- a protein that the malaria pathogen Plasmodium falciparum uses to invade red blood cells -- can generate a promising immune response that is most pronounced in an infant cohort. Fri, 11 Aug 2023 11:54:33 EDT //www.koonmotors.com/releases/2023/08/230811115433.htm //www.koonmotors.com/releases/2023/08/230810180123.htm Researchers have found that the genes of the mitochondria, the energy producers of our cells, can be negatively impacted by the virus, leading to dysfunction in multiple organs beyond the lungs. These findings suggest new approaches for treating COVID-19. Thu, 10 Aug 2023 18:01:23 EDT //www.koonmotors.com/releases/2023/08/230810180123.htm //www.koonmotors.com/releases/2023/08/230810141004.htm A change in just one letter in the code that makes up a cancer-causing gene can significantly affect how aggressive a tumor is or how well a patient with cancer responds to a particular therapy. A new, very precise gene-editing tool will enable scientists to study the impact of these specific genetic changes in preclinical models rather than being limited to more broadly targeted tactics, such as deleting the entire gene. Thu, 10 Aug 2023 14:10:04 EDT //www.koonmotors.com/releases/2023/08/230810141004.htm //www.koonmotors.com/releases/2023/08/230810110414.htm Researchers created a germ-free mouse model to evaluate the role of the microbiome in the infection, replication, and pathogenesis of HIV and the Epstein-Barr virus, the virus that can cause mononucleosis and other serious diseases. Thu, 10 Aug 2023 11:04:14 EDT //www.koonmotors.com/releases/2023/08/230810110414.htm //www.koonmotors.com/releases/2023/08/230810110340.htm Researchers have made a remarkable step forward in finding a potential cure for a type of childhood kidney disease. Thu, 10 Aug 2023 11:03:40 EDT //www.koonmotors.com/releases/2023/08/230810110340.htm //www.koonmotors.com/releases/2023/08/230810110315.htm A new observation suggests that a life-threatening blood clotting disorder can be caused by an infection with adenovirus, one of the most common respiratory viruses in pediatric and adult patients. Thu, 10 Aug 2023 11:03:15 EDT //www.koonmotors.com/releases/2023/08/230810110315.htm //www.koonmotors.com/releases/2023/08/230810110313.htm A study has identified a new pathway that human immune deficiency virus (HIV) uses to enter the nucleus of a healthy cell, where it can then replicate and go on to invade other cells. Thu, 10 Aug 2023 11:03:13 EDT //www.koonmotors.com/releases/2023/08/230810110313.htm //www.koonmotors.com/releases/2023/08/230810110310.htm Following the first stay-at-home orders issued in the U.S. to curb the spread of COVID-19, gastrointestinal viruses such as norovirus, rotavirus and adenovirus all but disappeared from California communities, and remained at very low levels for nearly 2 years, according to new research. Thu, 10 Aug 2023 11:03:10 EDT //www.koonmotors.com/releases/2023/08/230810110310.htm //www.koonmotors.com/releases/2023/08/230809130619.htm Two oral drugs, molnupiravir and paxlovid (nirmatrelvir/ritonavir), provide equivalent therapeutic benefit in preventing severe COVID-19 in animal models, but only molnupiravir efficiently blocked SARS-CoV-2 transmission when administered at a human effect size-equivalent dose, according to a new study. Wed, 09 Aug 2023 13:06:19 EDT //www.koonmotors.com/releases/2023/08/230809130619.htm //www.koonmotors.com/releases/2023/08/230809130610.htm The drug tecovirimat is currently in use for the treatment of mpox -- the disease caused by monkeypox virus -- that spread worldwide in 2022. Tecovirimat is an anti-poxviral drug, and its use is driving the emergence of drug-resistant variants of the monkeypox virus. Scientists have identified how monkeypox virus exploits a cellular protein to evade host defenses, allowing it to replicate and spread better. Existing drugs -- developed to treat other viral infections -- also target this cellular protein. When tested against a range of poxviruses, including monkeypox, these drugs were found to have antiviral effects in all cases. Wed, 09 Aug 2023 13:06:10 EDT //www.koonmotors.com/releases/2023/08/230809130610.htm //www.koonmotors.com/releases/2023/08/230808110836.htm 一些hiv - 1航空公司获得了早期的蚂蚁iretroviral treatment during several years are able to control the virus for a long term after treatment interruption. However, the mechanisms enabling this post-treatment control have not been fully elucidated. Scientists have now investigated and revealed how neutralizing antibodies, including those described as broadly neutralizing, contribute to virus control. A clinical trial involving the use of broadly neutralizing antibodies should begin in France before the end of 2023. Tue, 08 Aug 2023 11:08:36 EDT //www.koonmotors.com/releases/2023/08/230808110836.htm //www.koonmotors.com/releases/2023/08/230807121925.htm Epstein-Barr virus (EBV) infection is known to convert resting B lymphocytes into immortal cells that continuously multiply, leading to posttransplant lymphoproliferative disorder (PTLD). Researchers have now uncovered the molecular mechanisms of this growth transformation, demonstrating the crucial role of the cancer-related gene IMPDH2 and nucleolar enlargement. Additionally, the research revealed strong evidence supporting the efficacy of mycophenolate mofetil, an approved immunosuppressant, in inhibiting PTLD, highlighting its therapeutic significance. Mon, 07 Aug 2023 12:19:25 EDT //www.koonmotors.com/releases/2023/08/230807121925.htm //www.koonmotors.com/releases/2023/08/230804123751.htm Researchers have discovered a previously unknown mechanism by which bacteria share their genetic material through virus parasites. The insights could help scientists to better understand how bacteria rapidly adapt and evolve, and how they become more virulent and resistant to antibiotics. Fri, 04 Aug 2023 12:37:51 EDT //www.koonmotors.com/releases/2023/08/230804123751.htm //www.koonmotors.com/releases/2023/08/230804123656.htm 在温带气候,如北美和欧洲pe, flu season starts in the fall, peaks in the winter and ends in the spring. While public health officials have generally assumed that influenza is also seasonal in tropical climates, new research has found little evidence of a repeatable pattern in influenza cases in Vietnam. The findings suggest that influenza is likely unpredictable throughout the tropics, posing substantial challenges for prevention and management of cases for the one-third of the global population living in tropical areas. Fri, 04 Aug 2023 12:36:56 EDT //www.koonmotors.com/releases/2023/08/230804123656.htm //www.koonmotors.com/releases/2023/08/230803112925.htm A research team has published rigorous new research that advances a quest to understand a puzzling -- and heartbreaking -- ultra-rare disease that's found almost exclusively in boys. Thu, 03 Aug 2023 11:29:25 EDT //www.koonmotors.com/releases/2023/08/230803112925.htm //www.koonmotors.com/releases/2023/08/230802132005.htm A study on almost four thousand people of African descent has identified a gene that acts as natural defense against HIV by limiting its replication in certain white blood cells. This research paves the way for new treatment strategies and underscores the importance of studying diverse ancestral populations to better address their specific medical needs and global health disparities. Wed, 02 Aug 2023 13:20:05 EDT //www.koonmotors.com/releases/2023/08/230802132005.htm //www.koonmotors.com/releases/2023/08/230802105830.htm A team of scientists has made an important breakthrough in the fight against RNA viruses that cause human diseases and pandemics. Wed, 02 Aug 2023 10:58:30 EDT //www.koonmotors.com/releases/2023/08/230802105830.htm //www.koonmotors.com/releases/2023/08/230802105805.htm Antiviral therapies are notoriously difficult to develop, as viruses can quickly mutate to become resistant to drugs. But what if a new generation of antivirals ignores the fast-mutating proteins on the surface of viruses and instead disrupts their protective layers? Wed, 02 Aug 2023 10:58:05 EDT //www.koonmotors.com/releases/2023/08/230802105805.htm //www.koonmotors.com/releases/2023/08/230801152851.htm The availability, speed and effectiveness of genomic sequencing increased dramatically during the pandemic, as scientists worldwide rushed to find ways to track and predict the virus's movement and evolution. It also was critical in the development of effective vaccines. Biologists argue that building on this momentum is critical in society's response to future pandemics, but it requires significant collaboration and investment now, before the next pathogen is threatening society. Tue, 01 Aug 2023 15:28:51 EDT //www.koonmotors.com/releases/2023/08/230801152851.htm //www.koonmotors.com/releases/2023/08/230801131658.htm Researchers have developed a device -- a breath test that uses a biosensor -- as a tool for use in doctors' offices and crowded public locations to quickly diagnose people infected with the virus that causes COVID-19. Tue, 01 Aug 2023 13:16:58 EDT //www.koonmotors.com/releases/2023/08/230801131658.htm //www.koonmotors.com/releases/2023/07/230728170622.htm Scientists showed that fixed mutations within a viral population most likely stem from how easy it is to acquire that mutation (i.e., mutation accessibility) rather than just its benefit. Fri, 28 Jul 2023 17:06:22 EDT //www.koonmotors.com/releases/2023/07/230728170622.htm //www.koonmotors.com/releases/2023/07/230727212040.htm Scientists identified the region where a protein regulates sodium ion channels, inserting the channel's genetic material into a virus to alleviate pain in cell and animal studies. Thu, 27 Jul 2023 21:20:40 EDT //www.koonmotors.com/releases/2023/07/230727212040.htm //www.koonmotors.com/releases/2023/07/230727143917.htm A new study of the strain of influenza A responsible for the 2009 H1N1 pandemic -- pdm09 -- shows that the virus has passed from humans to swine about 370 times since 2009, and subsequent circulation in swine has resulted in the evolution of pdm09 variants that then jumped from swine to humans. Thu, 27 Jul 2023 14:39:17 EDT //www.koonmotors.com/releases/2023/07/230727143917.htm //www.koonmotors.com/releases/2023/07/230726113100.htm Dozens of viruses -- at least -- can eavesdrop on host information. Not only did they demonstrate the strategy's abundance, but they also discovered tools that control it and send signals that tell bacteriophage viruses to flip from chill (lysogeny) into kill (lysis) mode. They showed that in polylysogeny, phages can coexist, their viral DNA or RNA hidden tucked inside the bacterium's own, replicating right along with the cells. But the infiltrating phages aren't exactly peaceful; it's more like mutually assured destruction. And the tenuous detente lasts only until something triggers one or more of the phages to switch into kill mode. 结婚,2023年7月26日11:31:00美国东部时间 //www.koonmotors.com/releases/2023/07/230726113100.htm //www.koonmotors.com/releases/2023/07/230726113046.htm The results of a novel study has revealed exciting findings in the pursuit of an HIV cure. Wed, 26 Jul 2023 11:30:46 EDT //www.koonmotors.com/releases/2023/07/230726113046.htm //www.koonmotors.com/releases/2023/07/230725123047.htm In 2022-2023, an outbreak of monkeypox, now known as mpox (caused by the monkeypox virus or MPXV) led to 87,000 human cases in 170 countries. Most cases were reported outside the usual areas in which the virus circulates. Since the outbreak began, surveillance of the virus has been stepped up in Europe, with nearly 5,000 cases being reported in France. Tue, 25 Jul 2023 12:30:47 EDT //www.koonmotors.com/releases/2023/07/230725123047.htm //www.koonmotors.com/releases/2023/07/230724182719.htm Researchers have discovered that the sentinels guarding the healthy human cornea from pathogens and inflammation are T cells, and not another type of immune cells called dendritic cells, as previously thought. Mon, 24 Jul 2023 18:27:19 EDT //www.koonmotors.com/releases/2023/07/230724182719.htm //www.koonmotors.com/releases/2023/07/230724122649.htm Taking a significant leap in the field of vaccine development, Schulich School of Medicine & Dentistry researchers have discovered a potential 'super molecule' that can bolster the effectiveness of several vaccines against viral diseases, including influenza, COVID-19 and smallpox. Mon, 24 Jul 2023 12:26:49 EDT //www.koonmotors.com/releases/2023/07/230724122649.htm //www.koonmotors.com/releases/2023/07/230724122454.htm While the incidence of influenza-associated neuropsychiatric events in children in the United States is unknown, the controversy over the use of a common antiviral medication typically administered to treat flu in children has sparked concern among parents and medical professionals alike. Mon, 24 Jul 2023 12:24:54 EDT //www.koonmotors.com/releases/2023/07/230724122454.htm //www.koonmotors.com/releases/2023/07/230722004700.htm Researchers have discovered the molecular mechanisms by which the human immunodeficiency virus (HIV) becomes resistant to Dolutegravir, one of the most effective, clinically used antiviral drugs for treating HIV. Their findings reveal how changes to the 3D structures of integrase, an HIV protein, can lead to Dolutegravir resistance and how other compounds may be able to overcome this resistance. Sat, 22 Jul 2023 00:47:00 EDT //www.koonmotors.com/releases/2023/07/230722004700.htm //www.koonmotors.com/releases/2023/07/230721113235.htm The new carbon nanotube sensor design resembles a molecular toolbox that can be used to quickly assemble sensors for a variety of purposes -- for instance for detecting bacteria and viruses. Fri, 21 Jul 2023 11:32:35 EDT //www.koonmotors.com/releases/2023/07/230721113235.htm //www.koonmotors.com/releases/2023/07/230721113224.htm Researchers have found that people with longer-term COVID-19 symptoms including brain fog showed reduced performance in tasks testing different mental processes up to two years after infection with the virus. Fri, 21 Jul 2023 11:32:24 EDT //www.koonmotors.com/releases/2023/07/230721113224.htm //www.koonmotors.com/releases/2023/07/230721113204.htm Machine-learning system effectively predicts emergence of prominent variants. Fri, 21 Jul 2023 11:32:04 EDT //www.koonmotors.com/releases/2023/07/230721113204.htm //www.koonmotors.com/releases/2023/07/230719112613.htm People who contract COVID-19 but never develop symptoms -- the so-called super dodgers -- may have a genetic ace up their sleeve. They're more than twice as likely as those who become symptomatic to carry a specific gene variation that helps them obliterate the virus, according to a new study. Wed, 19 Jul 2023 11:26:13 EDT //www.koonmotors.com/releases/2023/07/230719112613.htm //www.koonmotors.com/releases/2023/07/230717175955.htm A team of researchers published new findings that emphasize the crucial role of the urinary and genital tract microbiota in adverse pregnancy outcomes and genomic instability that originate in the womb during fetal development. The study established a new link between genomic instability and a protein from Mycoplasma fermentans, a kind of bacterium that commonly colonizes the urogenital tract. This bacterial protein also reduced fertility in mother mice and resulted in more birth defects in their newborn pups. Mon, 17 Jul 2023 17:59:55 EDT //www.koonmotors.com/releases/2023/07/230717175955.htm //www.koonmotors.com/releases/2023/07/230717175950.htm Researchers have shown for the first time how Merkel cell polyomavirus (MCV), which causes an aggressive skin cancer called Merkel cell carcinoma, initiates DNA replication in host cells. Mon, 17 Jul 2023 17:59:50 EDT //www.koonmotors.com/releases/2023/07/230717175950.htm //www.koonmotors.com/releases/2023/07/230717115818.htm Researchers are using DNA 'origami' templates to control the way viruses are assembled. The global team behind the research developed a way to direct the assembly of virus capsids -- the protein shell of viruses -- at physiological conditions in a precise and programmable manner. Precise control over the size and shape of virus proteins would have advantages in the development of new vaccines and delivery systems. Mon, 17 Jul 2023 11:58:18 EDT //www.koonmotors.com/releases/2023/07/230717115818.htm //www.koonmotors.com/releases/2023/07/230714114736.htm Antibodies are crucial, not only for treating tumors and infections. Sometimes, however, the immune reaction they trigger can be too strong and end up causing more damage, for example in the case of people infected with Covid-19. Problems such as these can often be avoided by finetuning antibodies, according to new research. Fri, 14 Jul 2023 11:47:36 EDT //www.koonmotors.com/releases/2023/07/230714114736.htm