//www.koonmotors.com/news/health_medicine/vaccines/ News on vaccines including HPV vaccine, shingles vaccine, bird flu vaccines and more. Read the latest research on vaccination risks and complications. en-us Sat, 09 Sep 2023 10:47:42 EDT Sat, 09 Sep 2023 10:47:42 EDT 60 //www.koonmotors.com/images/scidaily-logo-rss.png//www.koonmotors.com/news/health_medicine/vaccines/ For more science news, visit ScienceDaily. //www.koonmotors.com/releases/2023/09/230907130332.htm By adding synergistic self-adjuvanting properties to Covid-19 RNA vaccines, researchers showed they could significantly boost the immune response generated in mice. Thu, 07 Sep 2023 13:03:32 EDT //www.koonmotors.com/releases/2023/09/230907130332.htm //www.koonmotors.com/releases/2023/09/230905124929.htm A new international study has shown mpox (formerly known as monkeypox) infections to be less severe among those who are vaccinated or had a previous infection in 2022, underlining the importance and effectiveness of vaccination. Tue, 05 Sep 2023 12:49:29 EDT //www.koonmotors.com/releases/2023/09/230905124929.htm //www.koonmotors.com/releases/2023/09/230904104633.htm ChatGPT could help to increase vaccine uptake by debunking myths around jab safety, say the authors of a new study. Mon, 04 Sep 2023 10:46:33 EDT //www.koonmotors.com/releases/2023/09/230904104633.htm //www.koonmotors.com/releases/2023/08/230831164439.htm Researchers have determined how Leishmaniasis vaccine candidates, created using mutated disease-causing parasites, prompt molecular-level changes in host cells that have specific roles in helping generate the immune response. Thu, 31 Aug 2023 16:44:39 EDT //www.koonmotors.com/releases/2023/08/230831164439.htm //www.koonmotors.com/releases/2023/08/230824003813.htm Researchers are on the brink of a technological breakthrough in vaccine development with a possible new vaccine modality. Thu, 24 Aug 2023 00:38:13 EDT //www.koonmotors.com/releases/2023/08/230824003813.htm //www.koonmotors.com/releases/2023/08/230817163908.htm Scientists found that immune cells present in individuals long before influenza infection predict whether the illness is symptomatic. Thu, 17 Aug 2023 16:39:08 EDT //www.koonmotors.com/releases/2023/08/230817163908.htm //www.koonmotors.com/releases/2023/08/230816170628.htm Prior vaccination against tetanus and diphtheria, with or without pertussis (Tdap/Td); herpes zoster (HZ), better known as shingles; and pneumococcus are all associated with a reduced risk for developing Alzheimer's disease, according to new research. Wed, 16 Aug 2023 17:06:28 EDT //www.koonmotors.com/releases/2023/08/230816170628.htm //www.koonmotors.com/releases/2023/08/230816114132.htm A psychological study suggests our brain can assess the state of our own health more precisely than we think -- and it is probably even able to correctly evaluate the state of our immune system. Wed, 16 Aug 2023 11:41:32 EDT //www.koonmotors.com/releases/2023/08/230816114132.htm //www.koonmotors.com/releases/2023/08/230811143836.htm Receiving a COVID-19 mRNA vaccine or booster during pregnancy can benefit pregnant people and their newborn infants, according to new findings. Fri, 11 Aug 2023 14:38:36 EDT //www.koonmotors.com/releases/2023/08/230811143836.htm //www.koonmotors.com/releases/2023/08/230811115433.htm An experimental malaria vaccine appears safe and promotes an immune response in African infants, one of the groups most vulnerable to severe malaria disease. There is currently only one malaria vaccine, 'RTS,S' that is approved by the World Health Organization and offers partial disease protection. However, in the results of the early-stage phase Ib trial, researchers find that targeting RH5 -- a protein that the malaria pathogen Plasmodium falciparum uses to invade red blood cells -- can generate a promising immune response that is most pronounced in an infant cohort. Fri, 11 Aug 2023 11:54:33 EDT //www.koonmotors.com/releases/2023/08/230811115433.htm //www.koonmotors.com/releases/2023/08/230810110315.htm A new observation suggests that a life-threatening blood clotting disorder can be caused by an infection with adenovirus, one of the most common respiratory viruses in pediatric and adult patients. Thu, 10 Aug 2023 11:03:15 EDT //www.koonmotors.com/releases/2023/08/230810110315.htm //www.koonmotors.com/releases/2023/08/230804123656.htm In temperate climates, like North America and Europe, flu season starts in the fall, peaks in the winter and ends in the spring. While public health officials have generally assumed that influenza is also seasonal in tropical climates, new research has found little evidence of a repeatable pattern in influenza cases in Vietnam. The findings suggest that influenza is likely unpredictable throughout the tropics, posing substantial challenges for prevention and management of cases for the one-third of the global population living in tropical areas. Fri, 04 Aug 2023 12:36:56 EDT //www.koonmotors.com/releases/2023/08/230804123656.htm //www.koonmotors.com/releases/2023/08/230802132012.htm A study of older U.S. adults found that the risk of negative effects of both mRNA vaccines is exceptionally low, but lowest with the Moderna vaccine. Wed, 02 Aug 2023 13:20:12 EDT //www.koonmotors.com/releases/2023/08/230802132012.htm //www.koonmotors.com/releases/2023/07/230725123047.htm In 2022-2023, an outbreak of monkeypox, now known as mpox (caused by the monkeypox virus or MPXV) led to 87,000 human cases in 170 countries. Most cases were reported outside the usual areas in which the virus circulates. Since the outbreak began, surveillance of the virus has been stepped up in Europe, with nearly 5,000 cases being reported in France. Tue, 25 Jul 2023 12:30:47 EDT //www.koonmotors.com/releases/2023/07/230725123047.htm //www.koonmotors.com/releases/2023/07/230724122649.htm Taking a significant leap in the field of vaccine development, Schulich School of Medicine & Dentistry researchers have discovered a potential 'super molecule' that can bolster the effectiveness of several vaccines against viral diseases, including influenza, COVID-19 and smallpox. Mon, 24 Jul 2023 12:26:49 EDT //www.koonmotors.com/releases/2023/07/230724122649.htm //www.koonmotors.com/releases/2023/07/230720124846.htm A new mRNA vaccine targeting immune cells in the liver could be the key to tackling malaria, a disease that causes over half a million deaths each year according to the World Health Organization, yet has no effective long-lasting vaccine. Thu, 20 Jul 2023 12:48:46 EDT //www.koonmotors.com/releases/2023/07/230720124846.htm //www.koonmotors.com/releases/2023/07/230718105627.htm Researchers have uncovered two new cholera substrains in a displaced refugee population in southern Bangladesh, where a pre-emptive mass vaccination campaign of over one million refugees was successful in preventing an epidemic. They also showed that the cholera bacterium initiating this campaign was the high risk pandemic strain that has caused outbreaks of cholera globally. Tue, 18 Jul 2023 10:56:27 EDT //www.koonmotors.com/releases/2023/07/230718105627.htm //www.koonmotors.com/releases/2023/07/230717143218.htm Columbia researchers have found why babies are susceptible to repeated bouts of common respiratory infections--but also have a unique weapon to fight off new pathogens that healthy adults lack. Mon, 17 Jul 2023 14:32:18 EDT //www.koonmotors.com/releases/2023/07/230717143218.htm //www.koonmotors.com/releases/2023/07/230717115358.htm Giving patients with operable pancreatic cancers a three-pronged combination immunotherapy treatment consisting of the pancreatic cancer vaccine GVAX, the immune checkpoint therapy nivolumab and urelemab, an anti-CD137 agonist antibody treatment, is safe, it increases the amount of cancer-killing immune system T cells in the tumors and it appears effective when given two weeks prior to cancer-removal surgery, according to new research. Mon, 17 Jul 2023 11:53:58 EDT //www.koonmotors.com/releases/2023/07/230717115358.htm //www.koonmotors.com/releases/2023/07/230705115136.htm A new vaccine boosts the response of engineered CAR-T cells and helps the immune system generate T cells that target other tumor antigens. The researchers found this approach made it more likely that a tumor can be eradicated in mice. Wed, 05 Jul 2023 11:51:36 EDT //www.koonmotors.com/releases/2023/07/230705115136.htm //www.koonmotors.com/releases/2023/07/230705105841.htm A research group used a unique 'PureCap' method to produce high purity mRNA vaccines with improved synthesis of proteins that stimulate the immune system and low inflammatory side effects. Wed, 05 Jul 2023 10:58:41 EDT //www.koonmotors.com/releases/2023/07/230705105841.htm //www.koonmotors.com/releases/2023/06/230627225147.htm Scientists have identified a signature in the blood that could help predict how well an individual will respond to vaccines. The discovery may explain why, even among vulnerable patient groups, some individuals have better responses to vaccines than others. Tue, 27 Jun 2023 22:51:47 EDT //www.koonmotors.com/releases/2023/06/230627225147.htm //www.koonmotors.com/releases/2023/06/230621164803.htm A new survey finds that the American public is ill-informed about RSV, unfamiliar with its most common symptoms, and more hesitant to recommend a vaccine against it to pregnant people than to older adults. Wed, 21 Jun 2023 16:48:03 EDT //www.koonmotors.com/releases/2023/06/230621164803.htm //www.koonmotors.com/releases/2023/06/230614220021.htm Despite some of the most successful international vaccination campaigns in history, the poliovirus continues to circulate around the world, posing a threat of neurological damage and even paralysis to anyone who is not vaccinated. Wed, 14 Jun 2023 22:00:21 EDT //www.koonmotors.com/releases/2023/06/230614220021.htm //www.koonmotors.com/releases/2023/05/230530174312.htm Scientists have spent years trying to develop an effective HIV vaccine, but none have proven successful. Based on findings from a recently published study, a research team may have put science one step closer to that goal. Tue, 30 May 2023 17:43:12 EDT //www.koonmotors.com/releases/2023/05/230530174312.htm //www.koonmotors.com/releases/2023/05/230524210512.htm By comparing the structures of protein complexes from different lineages of the dangerous Lassa virus, a team identified new antibodies and vaccine targets. Wed, 24 May 2023 21:05:12 EDT //www.koonmotors.com/releases/2023/05/230524210512.htm //www.koonmotors.com/releases/2023/05/230524181935.htm A new study has shown that human T cells have an important role to play in controlling infection. Wed, 24 May 2023 18:19:35 EDT //www.koonmotors.com/releases/2023/05/230524181935.htm //www.koonmotors.com/releases/2023/05/230523123725.htm Vaccines against smallpox given until the mid-1970s offer continuing cross-reactive immunity to mpox (previously known as monkeypox), researchers report. Tue, 23 May 2023 12:37:25 EDT //www.koonmotors.com/releases/2023/05/230523123725.htm //www.koonmotors.com/releases/2023/05/230522131258.htm Researchers have shown that within immune structures called the germinal centre, the mislocation of Tfh cells causes reduced capacity to respond well to vaccination with age. The research also identified that Tfh cells have a previously unappreciated role in supporting stromal cell responses to vaccines. The research demonstrates that age-dependent defects in the germinal centre response are reversible. These findings add to our understanding of the mechanisms behind a reduced immune response with age, allowing strategies to be developed to overcome or correct these to ensure the generation of robust immunological memory after vaccination. Mon, 22 May 2023 13:12:58 EDT //www.koonmotors.com/releases/2023/05/230522131258.htm //www.koonmotors.com/releases/2023/05/230509122018.htm New research found that people living with HIV that have had pulmonary tuberculosis had broader and more potent HIV antibody responses and differences in HIV sequences predicted to be antibody resistant as compared to those without suspected or documented tuberculosis. Tue, 09 May 2023 12:20:18 EDT //www.koonmotors.com/releases/2023/05/230509122018.htm //www.koonmotors.com/releases/2023/04/230412131152.htm Developing and testing new treatments or vaccines for humans almost always requires animal trials, but these experiments can sometimes take years to complete and can raise ethical concerns about the animals' treatment. Now, researchers reporting in ACS Central Science have developed a new testing platform that encapsulates B cells -- some of the most important components of the immune system -- into miniature 'organoids' to make vaccine screening quicker and greatly reduce the number of animals needed. Wed, 12 Apr 2023 13:11:52 EDT //www.koonmotors.com/releases/2023/04/230412131152.htm //www.koonmotors.com/releases/2023/04/230411150452.htm Researchers have found a creative way to make a vaccine for norovirus, the leading cause of foodborne infections, by piggybacking on rotavirus, an unrelated virus for which there are already several highly effective vaccines. Tue, 11 Apr 2023 15:04:52 EDT //www.koonmotors.com/releases/2023/04/230411150452.htm //www.koonmotors.com/releases/2023/04/230404114202.htm New research suggests that transposable elements in various cancers potentially may be used to direct novel immunotherapies to tumors that don't typically respond to immune-based treatments. Tue, 04 Apr 2023 11:42:02 EDT //www.koonmotors.com/releases/2023/04/230404114202.htm //www.koonmotors.com/releases/2023/03/230323154211.htm The medicinal secrets of the Chilean soapbark tree have been laid bare, unlocking a future of more potent, affordable, and sustainably sought vaccines. Researchers have taken a major step forward in addressing this problem, by using a combination of genome mining and bioengineering techniques to produce saponin-based vaccine adjuvants in the laboratory without harvesting material directly from trees. Thu, 23 Mar 2023 15:42:11 EDT //www.koonmotors.com/releases/2023/03/230323154211.htm //www.koonmotors.com/releases/2023/03/230322190857.htm Memory B cells play a critical role to provide long-term immunity after a vaccination or infection. Researchers have now described a distinct and novel subset of memory B cells that predict long-lived antibody responses to influenza vaccination in humans. These effector memory B cells appear to be poised for a rapid serum antibody response upon secondary challenge one year later. Wed, 22 Mar 2023 19:08:57 EDT //www.koonmotors.com/releases/2023/03/230322190857.htm //www.koonmotors.com/releases/2023/03/230314154913.htm A global maternal immunization program for group B Streptococcus -- strep B -- would save millions in healthcare costs by reducing death and disability, but without tiered pricing, equitable access would likely not be achieved. Several vaccines are currently under development, and an assessment of the impact and value of a global program has now been published. Tue, 14 Mar 2023 15:49:13 EDT //www.koonmotors.com/releases/2023/03/230314154913.htm //www.koonmotors.com/releases/2023/03/230313121003.htm We all know how important sleep is for mental health, but a meta-analysis found that getting good shut-eye also helps our immune systems respond to vaccination. The authors found that people who slept less than six hours per night produced significantly fewer antibodies than people who slept seven hours or more, and the deficit was equivalent to two months of antibody waning. Mon, 13 Mar 2023 12:10:03 EDT //www.koonmotors.com/releases/2023/03/230313121003.htm //www.koonmotors.com/releases/2023/03/230310123851.htm Researchers have created a radical new view of how immune cells recognise threats such as viruses. The discovery could be used to design better vaccines and to gain a deeper insight into autoimmune diseases and allergies. Fri, 10 Mar 2023 12:38:51 EST //www.koonmotors.com/releases/2023/03/230310123851.htm //www.koonmotors.com/releases/2023/03/230309124934.htm Researchers found evidence of heart muscle inflammation in a small number of patients with acute myocarditis after COVID-19 vaccination, but not in patients without acute myocarditis, according to a new study. Thu, 09 Mar 2023 12:49:34 EST //www.koonmotors.com/releases/2023/03/230309124934.htm //www.koonmotors.com/releases/2023/03/230306163012.htm A clinical trial testing a freeze-dried, temperature-stable experimental tuberculosis (TB) vaccine in healthy adults found that it was safe and stimulated both antibodies and responses from the cellular arm of the immune system. Mon, 06 Mar 2023 16:30:12 EST //www.koonmotors.com/releases/2023/03/230306163012.htm //www.koonmotors.com/releases/2023/02/230220121931.htm Analyzing the most extensive datasets in the U.S., researchers have revealed that vaccination against COVID-19 is associated with fewer heart attacks, strokes, and other cardiovascular issues among people who were infected with SARS-CoV-2, the virus that causes COVID-19. Mon, 20 Feb 2023 12:19:31 EST //www.koonmotors.com/releases/2023/02/230220121931.htm //www.koonmotors.com/releases/2023/02/230215155707.htm A new study in humans and mice shows the antibodies generated by your first COVID vaccination or infection can actually 'hurt' subsequent booster shots. That's because these antibodies rapidly 'mop up' the booster from the body, before it has a chance to stimulate the cells from the immune system. The scientists plan new experiments to administer drugs that transiently block antibody activity at the time of boosting to allow the vaccine to be sensed better by immune cells. Wed, 15 Feb 2023 15:57:07 EST //www.koonmotors.com/releases/2023/02/230215155707.htm //www.koonmotors.com/releases/2023/02/230208205411.htm Researchers have unlocked one of the secrets as to why some forms of Strep A are associated with severe invasive infection. Wed, 08 Feb 2023 20:54:11 EST //www.koonmotors.com/releases/2023/02/230208205411.htm //www.koonmotors.com/releases/2023/01/230131124430.htm A new vaccine could be the first clinically approved immunization to protect against invasive fungal infections, a growing concern as antifungal drug resistance increases. Fungal infections cause more than 1.5 million deaths worldwide each year and cost billions. They also double hospitalization costs, double the length of hospital stays and double the risk of death in hospitalized patients, according to a previous recent study. Tue, 31 Jan 2023 12:44:30 EST //www.koonmotors.com/releases/2023/01/230131124430.htm //www.koonmotors.com/releases/2023/01/230131124418.htm 一种新的方式来显著增加的效力almost any vaccine has been developed. The scientists used chemistry and nanotechnology to change the structural location of adjuvants and antigens on and within a nanoscale vaccine, greatly increasing vaccine performance in seven different types of cancer. The architecture is critical to vaccine effectiveness, the study shows. Tue, 31 Jan 2023 12:44:18 EST //www.koonmotors.com/releases/2023/01/230131124418.htm //www.koonmotors.com/releases/2023/01/230130130531.htm A new article shows that an experimental vaccine against Marburg virus (MARV) was safe and induced an immune response in a small, first-in-human clinical trial. The vaccine could someday be an important tool to respond to Marburg virus outbreaks. Mon, 30 Jan 2023 13:05:31 EST //www.koonmotors.com/releases/2023/01/230130130531.htm //www.koonmotors.com/releases/2023/01/230130130459.htm By repurposing one of the human body's natural cargo transports, a research team has developed a vaccine platform that could curb certain engineering challenges, storage demands and side effects of vaccines that combat HIV epidemics and the COVID-19 pandemic. Mon, 30 Jan 2023 13:04:59 EST //www.koonmotors.com/releases/2023/01/230130130459.htm //www.koonmotors.com/releases/2023/01/230120131249.htm Results from global data show vaccination and a prior COVID-19 infection offer the best defense against severe illness and reinfection. Fri, 20 Jan 2023 13:12:49 EST //www.koonmotors.com/releases/2023/01/230120131249.htm //www.koonmotors.com/releases/2023/01/230118134000.htm 一个亚临床实验的HIV疫苗方案测试g men who have sex with men (MSM) and transgender people was safe but did not provide protection against HIV acquisition, an independent data and safety monitoring board (DSMB) has determined. The HPX3002/HVTN 706, or 'Mosaico,' Phase 3 clinical trial began in 2019 and involved 3,900 volunteers ages 18 to 60 years in Europe, North America and South America. Based on the DSMB's recommendation, the study will be discontinued. Wed, 18 Jan 2023 13:40:00 EST //www.koonmotors.com/releases/2023/01/230118134000.htm //www.koonmotors.com/releases/2023/01/230117133654.htm A diverse immune response hinges on naive B cells mingling with high affinity ones in the late-stage germinal center. Whether that helps or hinders, however, depends on the virus. Tue, 17 Jan 2023 13:36:54 EST //www.koonmotors.com/releases/2023/01/230117133654.htm //www.koonmotors.com/releases/2023/01/230111131529.htm Vaccines that provide long-lasting protection against influenza, coronaviruses and respiratory syncytial virus (RSV) have proved exceptionally difficult to develop. Researchers now explore the challenges and outline approaches to improved vaccines. Wed, 11 Jan 2023 13:15:29 EST //www.koonmotors.com/releases/2023/01/230111131529.htm //www.koonmotors.com/releases/2023/01/230104154302.htm Investigators have developed a new cell therapy approach to eliminate established tumors and induce long-term immunity, training the immune system so that it can prevent cancer from recurring. Dual-action cell therapy engineered to eliminate established tumors and train the immune system to eradicate primary tumor and prevent cancer's recurrence. Wed, 04 Jan 2023 15:43:02 EST //www.koonmotors.com/releases/2023/01/230104154302.htm //www.koonmotors.com/releases/2023/01/230104135612.htm A three-dose regimen of a whole-parasite vaccine against malaria -- called Plasmodium falciparum sporozoite (PfSPZ) vaccine -- demonstrated safety and efficacy when tested in adults living in Burkina Faso, West Africa, which has endemic malaria. Wed, 04 Jan 2023 13:56:12 EST //www.koonmotors.com/releases/2023/01/230104135612.htm //www.koonmotors.com/releases/2023/01/230104115238.htm Researchers have found that immune systems of men who had recovered from mild cases of COVID-19 responded more robustly to flu vaccines than women who had had mild cases or men and women who had never been infected. In essence, the baseline immune statuses in men previously infected with SARS-CoV-2 was altered in ways that changed the response to an exposure different from SARS-CoV-2, the researchers report. Wed, 04 Jan 2023 11:52:38 EST //www.koonmotors.com/releases/2023/01/230104115238.htm //www.koonmotors.com/releases/2023/01/230104085231.htm Researchers extensively investigated the immune response of 16 adolescents and young adults who developed myocarditis after receipt of the COVID mRNA vaccine. The researchers found no differences in antibody production, auto-antibodies, T cell profiles, or prior viral exposures, but found elevated levels of spike protein along with increased cytokines (consistent with innate inflammation) and increased troponin (indicating cardiac injury). Wed, 04 Jan 2023 08:52:31 EST //www.koonmotors.com/releases/2023/01/230104085231.htm //www.koonmotors.com/releases/2023/01/230103133750.htm A study of children and adolescents who received a COVID-19 vaccination following multisystem inflammatory syndrome (MIS-C) found that there were no reports of serious complications including myocarditis or MIS-C reoccurrence. About half of participants experienced mild and typical reactions, including arm soreness and fatigue. The study demonstrates that it is safe to get a vaccine after having MIS-C. Tue, 03 Jan 2023 13:37:50 EST //www.koonmotors.com/releases/2023/01/230103133750.htm //www.koonmotors.com/releases/2023/01/230102114536.htm Vaccination and boosting, especially when recent, helped to limit the spread of COVID-19 in California prisons during the first Omicron wave, according to an analysis that examined transmission between people living in the same cell. Mon, 02 Jan 2023 11:45:36 EST //www.koonmotors.com/releases/2023/01/230102114536.htm //www.koonmotors.com/releases/2022/12/221228130409.htm Researchers have found that antigen-specific killer T cells (CD8+ T cells) rapidly expand in the lungs when primed by antigen-presenting lung-resident alveolar macrophages (AMs). This interaction helps protect against viral infection and could form the basis for developing 'cell transplant'-type vaccines in the future. Wed, 28 Dec 2022 13:04:09 EST //www.koonmotors.com/releases/2022/12/221228130409.htm //www.koonmotors.com/releases/2022/12/221226094532.htm While most germinal centers shut down after a few weeks, some stay in business for more than six months. A new study helps explain why. Mon, 26 Dec 2022 09:45:32 EST //www.koonmotors.com/releases/2022/12/221226094532.htm //www.koonmotors.com/releases/2022/12/221222123117.htm Researchers have demonstrated that people suffering from blood cancer have a good immune response to COVID-19 vaccinations. Vaccination protects patients with B-cell lymphoma and multiple myeloma against severe illness from COVID-19. Some patients even form highly potent antibodies. Thu, 22 Dec 2022 12:31:17 EST //www.koonmotors.com/releases/2022/12/221222123117.htm