//www.koonmotors.com/news/health_medicine/urology/ Current medical research in urology. Read about frequent urination and overactive bladder. Learn about urinary tract infections, prostate cancer symptoms, kidney stones and more. en-us Wed, 09 Aug 2023 13:46:13 EDT Wed, 09 Aug 2023 13:46:13 EDT 60 //www.koonmotors.com/images/scidaily-logo-rss.png//www.koonmotors.com/news/health_medicine/urology/ For more science news, visit ScienceDaily. //www.koonmotors.com/releases/2023/07/230719112707.htm Three new biomarkers for prostate cancer have been identified to help pinpoint potentially aggressive cases of the disease, which kills 300,000 men each year. Wed, 19 Jul 2023 11:27:07 EDT //www.koonmotors.com/releases/2023/07/230719112707.htm //www.koonmotors.com/releases/2023/07/230712124705.htm Prostate cancer is a leading cause of death among American men, and it's resistant to one of the most powerful chemotherapy medications -- cisplatin. Now, researchers have developed the first therapy of its kind that disrupts prostate cancer cells' metabolism and releases cisplatin into the weakened cells, causing them to die. In mouse models, an orally administered version shrunk tumors substantially. Wed, 12 Jul 2023 12:47:05 EDT //www.koonmotors.com/releases/2023/07/230712124705.htm //www.koonmotors.com/releases/2023/03/230316212552.htm The combination of two oral medications has shown positive results in people with prostate cancer, whose disease has spread to other parts of the body. Compared with XTANDI plus placebo, the investigatory combination of TALZENNA and XTANDI demonstrated a statistically significant and clinically meaningful improvement in radiographic progression-free survival. Thu, 16 Mar 2023 21:25:52 EDT //www.koonmotors.com/releases/2023/03/230316212552.htm //www.koonmotors.com/releases/2023/03/230309101400.htm New research shows that men who stick to a predominantly Mediterranean diet are less likely to be diagnosed with prostate cancer. This diet also improves their chances of recovery if they have PC and are undergoing radiation treatment. Thu, 09 Mar 2023 10:14:00 EST //www.koonmotors.com/releases/2023/03/230309101400.htm //www.koonmotors.com/releases/2023/03/230309071145.htm Researchers have developed an ultra-soft and highly stretchable tissue-adhesive hydrogel-based multifunctional implantable sensor for monitoring of overactive bladder. Thu, 09 Mar 2023 07:11:45 EST //www.koonmotors.com/releases/2023/03/230309071145.htm //www.koonmotors.com/releases/2023/02/230223132921.htm 肠漏,肛门失禁普罗特的必要性ection and a restricted social life may cause severe, decades-long suffering among women with obstetric injuries to the anal opening, according to a new study. Thu, 23 Feb 2023 13:29:21 EST //www.koonmotors.com/releases/2023/02/230223132921.htm //www.koonmotors.com/releases/2023/02/230207191546.htm Researchers have helped develop a new blood test to detect prostate cancer with greater accuracy than current methods. New research shows that the Prostate Screening EpiSwitch (PSE) blood test is 94 per cent accurate -- beating the currently used prostate-specific antigen (PSA) blood test. The research team say that the new test shows significant potential as an accurate and rapid cancer screening diagnostic. Tue, 07 Feb 2023 19:15:46 EST //www.koonmotors.com/releases/2023/02/230207191546.htm //www.koonmotors.com/releases/2023/01/230123200332.htm Researchers discover a potential therapeutic avenue via neuronal endocrine receptors that could be helpful in battling an aggressive form of prostate cancer. Mon, 23 Jan 2023 20:03:32 EST //www.koonmotors.com/releases/2023/01/230123200332.htm //www.koonmotors.com/releases/2022/12/221214092345.htm A single bout of exercise has been shown to elevate anti-cancer proteins called myokines in people with advanced prostate cancer, to levels which can significantly suppress tumour growth. Wed, 14 Dec 2022 09:23:45 EST //www.koonmotors.com/releases/2022/12/221214092345.htm //www.koonmotors.com/releases/2022/11/221129165854.htm A family history of cancer and genetic variants that might be inherited appear to be important risk factors for Black men diagnosed with early-onset prostate cancer, a study has found. Tue, 29 Nov 2022 16:58:54 EST //www.koonmotors.com/releases/2022/11/221129165854.htm //www.koonmotors.com/releases/2022/11/221122152758.htm Vaginal birth after a previous cesarean section is associated with an increased risk of pelvic floor surgery compared with planning another cesarean, according to a new study. The findings provide useful information to help women who have had a previous cesarean section when planning how to give birth in their next pregnancy. Tue, 22 Nov 2022 15:27:58 EST //www.koonmotors.com/releases/2022/11/221122152758.htm //www.koonmotors.com/releases/2022/10/221007190634.htm A new technique which combines the use of two ultrasound technologies may offer an option to move kidney stones out of the ureter with minimal pain and no anesthesia, according to a new feasibility study. Fri, 07 Oct 2022 19:06:34 EDT //www.koonmotors.com/releases/2022/10/221007190634.htm //www.koonmotors.com/releases/2022/10/221005141743.htm An epigenetics drug currently being used for the treatment of blood cancers and rare sarcomas can stop the growth of bladder cancer by activating the immune system, reports a new study in mice. The drug is now being tested in a national clinical trial for patients with late-stage bladder cancer. Wed, 05 Oct 2022 14:17:43 EDT //www.koonmotors.com/releases/2022/10/221005141743.htm //www.koonmotors.com/releases/2022/10/221003110230.htm New epigenetic biomarkers to predict more aggressive forms of prostate cancer have been discovered. Mon, 03 Oct 2022 11:02:30 EDT //www.koonmotors.com/releases/2022/10/221003110230.htm //www.koonmotors.com/releases/2022/09/220922124513.htm Researchers have identified critical genomic changes in response to abiraterone acetate/prednisone, a standard treatment option for men with progressive, incurable and castration-resistant prostate cancer. Thu, 22 Sep 2022 12:45:13 EDT //www.koonmotors.com/releases/2022/09/220922124513.htm //www.koonmotors.com/releases/2022/09/220921210011.htm Researchers have made an important discovery about how prostate cancer may start to develop. A new study reveals that the prostate as a whole, including cells that appear normal, is different in men with prostate cancer. It suggests that tissue cells throughout the whole prostate are primed and ready to develop prostate cancer. This means that it may be better to treat the whole prostate rather than only the areas in the prostate that have cancer. The team hope their work could help scientists better understand the causes of prostate cancer, and even prevent it altogether. Wed, 21 Sep 2022 21:00:11 EDT //www.koonmotors.com/releases/2022/09/220921210011.htm //www.koonmotors.com/releases/2022/09/220920100739.htm Lower immunity and recurring infections are common in type 1 and type 2 diabetes. Researchers now show that the immune system of people with diabetes has lower levels of the antimicrobial peptide psoriasin, which compromises the urinary bladder's cell barrier, increasing the risk of urinary tract infection. Tue, 20 Sep 2022 10:07:39 EDT //www.koonmotors.com/releases/2022/09/220920100739.htm //www.koonmotors.com/releases/2022/08/220818091300.htm A large-scale study looked at the impact of incorporating genetic risk for cancer into the GP triage and referral processes in the UK. The research concluded that considering genetic risk could improve referrals for those in need -- and importantly, avoid invasive biopsy investigations for those at low risk of cancer. Assessing genetic risk in primary care could lead to earlier diagnosis for men most at risk of prostate cancer. Thu, 18 Aug 2022 09:13:00 EDT //www.koonmotors.com/releases/2022/08/220818091300.htm //www.koonmotors.com/releases/2022/08/220803203926.htm Men with early, curable stages of prostate cancer are missing opportunities to have their cancer detected because national guidelines and media health campaigns focus on urinary symptoms despite a lack of scientific evidence, say experts in the UK. Wed, 03 Aug 2022 20:39:26 EDT //www.koonmotors.com/releases/2022/08/220803203926.htm //www.koonmotors.com/releases/2022/06/220615102926.htm High-intensity focused ultrasound (HIFU) can help some men with prostate cancer avoid surgery or radiation. Wed, 15 Jun 2022 10:29:26 EDT //www.koonmotors.com/releases/2022/06/220615102926.htm //www.koonmotors.com/releases/2022/06/220609195008.htm Male sex hormones interfere with the body's ability to fight bladder cancer, likely explaining why males experience higher cancer rates and more deadly disease, according to a new study. Thu, 09 Jun 2022 19:50:08 EDT //www.koonmotors.com/releases/2022/06/220609195008.htm //www.koonmotors.com/releases/2022/05/220526125753.htm Practice-changing research shows that a combination of androgen deprivation therapy -- a commonly used hormone injection -- plus pelvic lymph node radiation, kept nearly 90% of clinical trial patients' prostate cancer at bay for five years. Thu, 26 May 2022 12:57:53 EDT //www.koonmotors.com/releases/2022/05/220526125753.htm //www.koonmotors.com/releases/2022/04/220422114745.htm Over the past 15 years, public health authorities have downgraded recommendations for the prostate-specific antigen (PSA) test as a screening tool to reduce the overdiagnosis and overtreatment of men with low-grade prostate cancer. Now, researchers have found that while these efforts have been effective, the incidence of higher-grade disease and metastasis at diagnosis have risen. Fri, 22 Apr 2022 11:47:45 EDT //www.koonmotors.com/releases/2022/04/220422114745.htm //www.koonmotors.com/releases/2022/04/220404105723.htm Prostate cancers remain localized in the majority of cases, giving affected individuals a good chance of survival. However, about 20% of patients develop incurable metastatic prostate cancer, resulting in approximately 5,000 deaths each year in Austria alone. Medical research has not yet adequately explained why metastases occur in some people and not in others. A research team has now discovered specific changes in a protein that drive the growth and spread of prostate cancer. Mon, 04 Apr 2022 10:57:23 EDT //www.koonmotors.com/releases/2022/04/220404105723.htm //www.koonmotors.com/releases/2022/03/220314120700.htm A new study finds that the incidence rate of metastatic prostate cancer has significantly increased for men 45 and older and coincides with recommendations against routine prostate cancer screenings. Mon, 14 Mar 2022 12:07:00 EDT //www.koonmotors.com/releases/2022/03/220314120700.htm //www.koonmotors.com/releases/2022/03/220309104406.htm 膀胱过动症的女性经常frustrated with treatment, which leads to discontinuation of therapy. Asynchronous telehealth visits keep women engaged in follow-up care, accelerates trials of different medications and reinforces behavioral changes. The women in this pilot study reported improvement in symptoms and high satisfaction with asynchronous visits. Wed, 09 Mar 2022 10:44:06 EST //www.koonmotors.com/releases/2022/03/220309104406.htm //www.koonmotors.com/releases/2022/02/220228184019.htm An ultrasound scan can be used to detect cases of prostate cancer, according to new research. Mon, 28 Feb 2022 18:40:19 EST //www.koonmotors.com/releases/2022/02/220228184019.htm //www.koonmotors.com/releases/2022/02/220218110716.htm Results from an international, randomized, double-blind, placebo-controlled, phase 3 clinical trial indicate that adding the androgen-receptor inhibitor darolutamide to androgen-deprivation therapy and chemotherapy prolongs the survival of men with metastatic, hormone-sensitive prostate cancer. Fri, 18 Feb 2022 11:07:16 EST //www.koonmotors.com/releases/2022/02/220218110716.htm //www.koonmotors.com/releases/2022/01/220128100728.htm The combination of a novel blood test and magnetic resonance imaging (MRI) can reduce overdiagnosis of low-risk cancers as well as societal costs in prostate cancer screening, according to a cost-effectiveness study. Fri, 28 Jan 2022 10:07:28 EST //www.koonmotors.com/releases/2022/01/220128100728.htm //www.koonmotors.com/releases/2022/01/220127141613.htm A new analysis has uncovered a potential link between higher prostate cancer risk and genetic variants associated with higher bloodstream levels of the cholesterol-transporting molecule lipoprotein A. Thu, 27 Jan 2022 14:16:13 EST //www.koonmotors.com/releases/2022/01/220127141613.htm //www.koonmotors.com/releases/2022/01/220112121551.htm A molecular feature in prostate cancer, called endogenous retroviral (ERV) RNA, has been found to have prognostic value and also distinguish differences between men of African and European or Middle Eastern ancestry, according to a new study. The team also identified ERV expression signatures that may be useful for identifying prostate cancer patients at greatest risk of progression regardless of ancestry, which may also extend to progression in other cancers. Wed, 12 Jan 2022 12:15:51 EST //www.koonmotors.com/releases/2022/01/220112121551.htm //www.koonmotors.com/releases/2021/12/211215082038.htm If you're feeling more sudden urges to run to the bathroom as you age, you're not alone. A new study suggests postmenopausal women aged 45 to 54 years are more likely to have overactive bladder (OAB) syndrome. Additionally, obesity and multiple births put a woman at greater risk for stress urinary incontinence (SUI). Wed, 15 Dec 2021 08:20:38 EST //www.koonmotors.com/releases/2021/12/211215082038.htm //www.koonmotors.com/releases/2021/11/211129105542.htm Prostate cancer screening results differ in men taking cholesterol-lowering statin drugs compared with non-users, a study finds. In statin users, screening did not increase the incidence of prostate cancer as it did in other men. Mon, 29 Nov 2021 10:55:42 EST //www.koonmotors.com/releases/2021/11/211129105542.htm //www.koonmotors.com/releases/2021/11/211116111315.htm Researchers have pioneered a new method to track the progression of prostate cancer in mice, from its birth to its spread into other tissues. This approach allows researchers to study the origins of prostate cancer in a more realistic context than traditional methods allow. Tue, 16 Nov 2021 11:13:15 EST //www.koonmotors.com/releases/2021/11/211116111315.htm //www.koonmotors.com/releases/2021/11/211102210147.htm Researchers have shown that a prostate cancer urine test can identify men at 'intermediate risk' who can safely avoid immediate treatment and benefit from 'active surveillance' instead. Previously, the team's Prostate Urine Risk (PUR) test could identify men with high and low risk cancers. But thanks to some fine-tuning, it can now help men with intermediate-risk disease - for whom treatment options had been less clear. Tue, 02 Nov 2021 21:01:47 EDT //www.koonmotors.com/releases/2021/11/211102210147.htm //www.koonmotors.com/releases/2021/10/211028120417.htm 研究人员首次显示,死亡t-associated molecules in the gut are associated with aggressive prostate cancer, suggesting dietary interventions may help reduce risk. While more research will be necessary, the study's lead author says findings from the team's analysis of nearly 700 patients may have clinical implications for diagnosing and preventing lethal prostate cancer. Thu, 28 Oct 2021 12:04:17 EDT //www.koonmotors.com/releases/2021/10/211028120417.htm //www.koonmotors.com/releases/2021/10/211005101902.htm New research shows bed and rest might not be the best treatment for people suffering from cancer -- in fact, the opposite may be true. Researchers have discovered the proteins created by the body when exercising - called myokines -- can suppress tumor growth and even help actively fight cancerous cells. Tue, 05 Oct 2021 10:19:02 EDT //www.koonmotors.com/releases/2021/10/211005101902.htm //www.koonmotors.com/releases/2021/10/211001130256.htm More than half of U.S. women will experience at least one urinary tract infection (UTI) in their lifetimes, while a quarter will have a subsequent infection. Recurrent urinary tract infections are defined as two or more infections in six months or three or more in a year. Fri, 01 Oct 2021 13:02:56 EDT //www.koonmotors.com/releases/2021/10/211001130256.htm //www.koonmotors.com/releases/2021/09/210901100326.htm Two recent studies describe the potential of liquid biopsies to identify and track tumor growth in two very different cancers: bladder cancer and peripheral nerve tumors. Despite the differences between these cancers and their associated biopsies, the studies demonstrate the possible benefits of this relatively new tool in the fight against cancer. Wed, 01 Sep 2021 10:03:26 EDT //www.koonmotors.com/releases/2021/09/210901100326.htm //www.koonmotors.com/releases/2021/08/210819142747.htm Researchers have established one of the world's largest collections of living tumors from prostate cancer patients, accelerating the testing of new treatments for prostate cancer and leading to faster patient benefit. Thu, 19 Aug 2021 14:27:47 EDT //www.koonmotors.com/releases/2021/08/210819142747.htm //www.koonmotors.com/releases/2021/03/210308111839.htm Scientists have established organoid culture models from prostate tumor biopsies. These are small clusters of cells which can be used to test the efficacy of various drugs. In this way, it is possible to test which treatment will most likely benefit individual patients. Mon, 08 Mar 2021 11:18:39 EST //www.koonmotors.com/releases/2021/03/210308111839.htm //www.koonmotors.com/releases/2021/03/210301151532.htm Researchers describe a new vaccination strategy that they think could re-program the body to fight off the bacteria that cause urinary tract infections. Mon, 01 Mar 2021 15:15:32 EST //www.koonmotors.com/releases/2021/03/210301151532.htm //www.koonmotors.com/releases/2021/02/210225143648.htm A DNA-damaging bacterial toxin called colibactin is produced in patients with urinary tract infections (UTIs), according to a new study. Thu, 25 Feb 2021 14:36:48 EST //www.koonmotors.com/releases/2021/02/210225143648.htm //www.koonmotors.com/releases/2021/02/210217151130.htm 一项新的研究表明狗到d的能力etect aggressive prostate cancer from urine samples and suggests that an artificial neural network could learn from this olfactory ability, with an eye toward replicating it in novel detection tools. Wed, 17 Feb 2021 15:11:30 EST //www.koonmotors.com/releases/2021/02/210217151130.htm //www.koonmotors.com/releases/2021/02/210217151121.htm A new system can detect the chemical and microbial content of an air sample with even greater sensitivity than a dog's nose. Researchers coupled this to a machine-learning process that can identify the distinctive characteristics of the disease-bearing samples. Wed, 17 Feb 2021 15:11:21 EST //www.koonmotors.com/releases/2021/02/210217151121.htm //www.koonmotors.com/releases/2021/02/210211114008.htm A urine test could have avoided one third of unnecessary prostate cancer biopsies while failing to detect only a small number of cancers, according to a validation study that included more than 1,500 patients. Thu, 11 Feb 2021 11:40:08 EST //www.koonmotors.com/releases/2021/02/210211114008.htm //www.koonmotors.com/releases/2021/01/210111190137.htm Drinking several cups of coffee every day may be linked to a lower risk of developing prostate cancer, suggests a pooled data analysis of the available evidence. Mon, 11 Jan 2021 19:01:37 EST //www.koonmotors.com/releases/2021/01/210111190137.htm //www.koonmotors.com/releases/2021/01/210107135655.htm Improving imaging processes will lead to more successful treatments and help reduce morbidity in men with the disease. Thu, 07 Jan 2021 13:56:55 EST //www.koonmotors.com/releases/2021/01/210107135655.htm //www.koonmotors.com/releases/2021/01/210107125305.htm In a study to examine a Mediterranean diet in relation to prostate cancer progression in men on active surveillance, researchers found that men with localized prostate cancer who reported a baseline dietary pattern that more closely follows the key principles of a Mediterranean-style diet fared better over the course of their disease. Thu, 07 Jan 2021 12:53:05 EST //www.koonmotors.com/releases/2021/01/210107125305.htm //www.koonmotors.com/releases/2021/01/210105111658.htm New research has identified a new mechanism in which prostate cancer cells can 'switch' character and become resistant to therapy. These findings are an important development in unraveling how an aggressive subtype of prostate cancer, neuroendocrine prostate cancer (NEPC), develops after hormonal therapies. Tue, 05 Jan 2021 11:16:58 EST //www.koonmotors.com/releases/2021/01/210105111658.htm //www.koonmotors.com/releases/2020/11/201111153104.htm An implantable smart wrap that fits safely and securely around the bladder may one day help people who have under-active bladders, a condition that hinders patients from urinating regularly and comfortably, according to an international team of researchers. Wed, 11 Nov 2020 15:31:04 EST //www.koonmotors.com/releases/2020/11/201111153104.htm //www.koonmotors.com/releases/2020/11/201110154304.htm 研究人员发现了一种基因签名calized prostate cancer that predicts the cancer's odds of spreading and its response to a common treatment for advanced disease. Tue, 10 Nov 2020 15:43:04 EST //www.koonmotors.com/releases/2020/11/201110154304.htm //www.koonmotors.com/releases/2020/10/201014140958.htm Scientists have found that the main sensor protein enabling our sense of touch also underlies the feeling of having a full bladder and makes normal bladder function possible. The discovery marks a key advance in basic neurobiology and may also lead to better treatments for bladder control and urination problems, which are common especially among the elderly. Wed, 14 Oct 2020 14:09:58 EDT //www.koonmotors.com/releases/2020/10/201014140958.htm //www.koonmotors.com/releases/2020/10/201007123055.htm A new intraoperative imaging technique, Cerenkov luminescence imaging (CLI), can accurately assess surgical margins during radical prostatectomy, according to a first-in-human research. The feasibility study showed that 68Ga-PSMA CLI can image the entire excised prostate specimen's surface to detect prostate cancer tissue at the resection margin. Wed, 07 Oct 2020 12:30:55 EDT //www.koonmotors.com/releases/2020/10/201007123055.htm //www.koonmotors.com/releases/2020/10/201007123053.htm Researchers reported that the SUCLA2 gene is frequently involved in the deletion of the tumor suppressor gene RB1 in advanced prostate cancer. RB1 deletion makes cells resistant to hormone therapy but SUCLA2 deletion induces a metabolic weakness. The study showed that thymoquinone selectively killed SUCLA2-deficient prostate cancer cells in vitro and in vivo. The findings highlight a vulnerability of advanced prostate cancer cells that can be targeted by drugs. Wed, 07 Oct 2020 12:30:53 EDT //www.koonmotors.com/releases/2020/10/201007123053.htm //www.koonmotors.com/releases/2020/09/200929123451.htm An antibody for treating advanced prostate cancer improves progression-free survival in patients with metastasized, castration-resistant prostate cancer. This is the finding of the long-term analyses of an international phase 3 clinical trial. The study showed that overall survival was 2 - 3 times higher than in the placebo arm. Tue, 29 Sep 2020 12:34:51 EDT //www.koonmotors.com/releases/2020/09/200929123451.htm //www.koonmotors.com/releases/2020/06/200620141948.htm A novel formulation of the prostate cancer drug abiraterone acetate - currently marketed as Zytiga - will dramatically improve the quality of life for people suffering from prostate cancer, as pre-clinical trials show the new formulation improves the drug's effectiveness by 40 per cent. Sat, 20 Jun 2020 14:19:48 EDT //www.koonmotors.com/releases/2020/06/200620141948.htm //www.koonmotors.com/releases/2020/05/200528115749.htm A new type of test that uses complex sugars to detect prostate cancer earlier and with greater accuracy. Thu, 28 May 2020 11:57:49 EDT //www.koonmotors.com/releases/2020/05/200528115749.htm //www.koonmotors.com/releases/2020/05/200505105333.htm Researchers have developed a new device that can monitor bladder volume in real-time and effectively empty the bladder. Tue, 05 May 2020 10:53:33 EDT //www.koonmotors.com/releases/2020/05/200505105333.htm //www.koonmotors.com/releases/2020/04/200428225426.htm Researchers have recreated how toxins from smoking cause unique patterns of DNA damage. The discovery could help scientists better understand the cause of bladder cancer and the link to smoking. The causes of bladder cancer remain largely unknown, however smoking is seen as the main risk factor for the disease. Tue, 28 Apr 2020 22:54:26 EDT //www.koonmotors.com/releases/2020/04/200428225426.htm