//www.koonmotors.com/news/health_medicine/ulcers/ Read the latest medical research on ulcers - causes and treatments. Read about the role of bacteria in the gut. en-us Mon, 16 Oct 2023 22:45:57 EDT Mon, 16 Oct 2023 22:45:57 EDT 60 //www.koonmotors.com/images/scidaily-logo-rss.png//www.koonmotors.com/news/health_medicine/ulcers/ For more science news, visit ScienceDaily. //www.koonmotors.com/releases/2022/11/221104093252.htm A new study found that the risk of stomach bleeding caused by using aspirin long-term, can be reduced with a short course of antibiotics, potentially improving the safety of aspirin when used to prevent heart attacks, strokes and possibly some cancers. Fri, 04 Nov 2022 09:32:52 EDT //www.koonmotors.com/releases/2022/11/221104093252.htm //www.koonmotors.com/releases/2021/10/211014100121.htm Researchers have improved understanding of the molecular mechanisms of a key protein that makes the stomach acidic. Their findings could lead to better drugs for stomach ulcers and shed light on the functions of similar proteins across the human body. Thu, 14 Oct 2021 10:01:21 EDT //www.koonmotors.com/releases/2021/10/211014100121.htm //www.koonmotors.com/releases/2021/04/210412101911.htm Researchers found that H. pylori bacterial strains with low expression of a small RNA molecule called HPnc4160 are more likely to adapt to living in the human stomach. Gastric cancer patients have lower levels of HPnc4160, as well as higher levels of pathogenic bacterial proteins, than individuals without cancer. This work provides crucial knowledge for the development of new treatments for chronic H. pylori infections and gastric cancer. Mon, 12 Apr 2021 10:19:11 EDT //www.koonmotors.com/releases/2021/04/210412101911.htm //www.koonmotors.com/releases/2021/02/210225143712.htm Researchers have provided clues to how the gut and brain work together by studying health data from nearly half a million people. Thu, 25 Feb 2021 14:37:12 EST //www.koonmotors.com/releases/2021/02/210225143712.htm //www.koonmotors.com/releases/2020/05/200518154939.htm Using rabies virus injected into the stomach of rats, researchers trace the nerves back to the brain and find distinct 'fight or flight' and 'rest and digest' circuits. These results explain how mental states can affect the gut, and present new ways to treat gastrointestinal problems. 2020年5月18日星期一15:49:39美国东部时间 //www.koonmotors.com/releases/2020/05/200518154939.htm //www.koonmotors.com/releases/2020/01/200123152511.htm A new study shows how a common stomach bacterium is able to keep its corkscrew-like shape as it grows. Disrupting the shape could point the way for future, more-specialized antibiotics that prevent the bacterium from being harmful. Thu, 23 Jan 2020 15:25:11 EST //www.koonmotors.com/releases/2020/01/200123152511.htm //www.koonmotors.com/releases/2019/11/191114100907.htm Researchers have assessed Helicobacter pylori infection and gastric cancer risk in Americans, certain demographics and ethnic groups. Thu, 14 Nov 2019 10:09:07 EST //www.koonmotors.com/releases/2019/11/191114100907.htm //www.koonmotors.com/releases/2019/07/190708094227.htm In a recent study, researchers have uncovered the origin of a layer of cells that look like normal stomach lining on top of sites of stomach cancer: it is produced by the cancer tissue itself. Mon, 08 Jul 2019 09:42:27 EDT //www.koonmotors.com/releases/2019/07/190708094227.htm //www.koonmotors.com/releases/2019/05/190523135539.htm 睡眠质量差和消化性溃疡疾病(布丁,a condition when sores known as ulcers develop on the lining of your stomach or in the first part of your small intestine) are both major public health problems that affect the physical and psychological wellbeing of older adults. Thu, 23 May 2019 13:55:39 EDT //www.koonmotors.com/releases/2019/05/190523135539.htm //www.koonmotors.com/releases/2019/04/190416094121.htm 研究人员已经解决了几十年的神秘how stomach bacterium Helicobacter pylori causes gastric cancer. Using mouse models and human cancer cell lines, they showed that inflammation resulting from bacterial infection leads to the proliferation of gastric epithelial cells, which ultimately form gastric tumors. By blocking the protein pathway responsible for this proliferation, they prevented gastric tumor formation. Tue, 16 Apr 2019 09:41:21 EDT //www.koonmotors.com/releases/2019/04/190416094121.htm //www.koonmotors.com/releases/2018/09/180924105749.htm While human genetic mutations are involved in a small number of Parkinson's disease (PD) cases, the vast majority of cases are of unknown environmental causes, prompting enormous interest in identifying environmental risk factors involved. Mon, 24 Sep 2018 10:57:49 EDT //www.koonmotors.com/releases/2018/09/180924105749.htm //www.koonmotors.com/releases/2017/11/171128102912.htm Scientists have recently identified new strategies used by Helicobacter pylori bacteria to infect cells. By specifically targeting mitochondria these bacteria, despite being extracellular, can optimize infection in the host. These findings pave the way for new strategies to combat H. pylori infection, which is associated with most cases of gastric cancer and several other gastric disorders. Tue, 28 Nov 2017 10:29:12 EST //www.koonmotors.com/releases/2017/11/171128102912.htm //www.koonmotors.com/releases/2017/11/171108124144.htm The prognosis for people with an infected diabetic foot ulcer is worse than was previously thought, according to new research. More than half the patients in the research study did not see their ulcer heal over a year -- and one in seven had to have part or all of their foot amputated. Wed, 08 Nov 2017 12:41:44 EST //www.koonmotors.com/releases/2017/11/171108124144.htm //www.koonmotors.com/releases/2017/11/171102140511.htm Different changes to the microbial community of the stomach may explain why related conditions are associated with different risk levels and types of gastric tumor, according to a new study. Thu, 02 Nov 2017 14:05:11 EDT //www.koonmotors.com/releases/2017/11/171102140511.htm //www.koonmotors.com/releases/2017/06/170614211217.htm It was long thought that gastric ulcers and other digestive woes were brought about by stress. But in 2005, clinical fellow Barry J. Marshall and pathologist J. Robin Warren were awarded the Nobel Prize in Physiology or Medicine for recognizing the role of Helicobacter pylori in gastritis and peptic ulcer disease. Now physicians can point their collective fingers at H. pylori when it comes to a host of gastric maladies in their patients. Wed, 14 Jun 2017 21:12:17 EDT //www.koonmotors.com/releases/2017/06/170614211217.htm //www.koonmotors.com/releases/2017/03/170308131119.htm To establish chronic infection in the very acidic stomach, the gastric pathogen Helicobacter pylori uses a specific protein to attach to the protective pH-neutral mucous lining. New research shows how the BabA adhesin protein has a pH-responsive mechanism allowing H. pylori to rapidly detach from old cells before they reach the brunt of the gastric acid. The release mechanism lets the bacteria return to the pH neutral mucous lining and recycle the infection. Wed, 08 Mar 2017 13:11:19 EST //www.koonmotors.com/releases/2017/03/170308131119.htm //www.koonmotors.com/releases/2016/10/161018094227.htm Helicobacter pylori is a spiral bacterium that can colonize the human stomach, sometimes with fatal consequences. A research group has discovered a completely new approach to preventing or treating infections with this bacterium as well as secondary complications. Tue, 18 Oct 2016 09:42:27 EDT //www.koonmotors.com/releases/2016/10/161018094227.htm //www.koonmotors.com/releases/2016/10/161011141022.htm A common bacterium that more than half of people have in their gut can use hydrogen gas present in the gastrointestinal tract to inject a cancer-causing toxin into otherwise healthy cells, according to a recently published study. Tue, 11 Oct 2016 14:10:22 EDT //www.koonmotors.com/releases/2016/10/161011141022.htm //www.koonmotors.com/releases/2016/05/160510124501.htm 调查人员评估药物的疗效acitentan in reducing the number of new digital ulcers in patients with systemic sclerosis. Systemic sclerosis is a chronic multisystem autoimmune disease and multiorgan disease affecting the connective tissue of the skin and several internal organs. Digital ulcers occur in 35 percent to 68 percent of patients with systemic sclerosis and are associated with pain, disfigurement, poor quality of life, and disability. Tue, 10 May 2016 12:45:01 EDT //www.koonmotors.com/releases/2016/05/160510124501.htm //www.koonmotors.com/releases/2016/04/160425100207.htm The beliefs and expectations of people with diabetic foot ulcers about their illness have a significant independent effect on their survival, new research by health psychologists has shown. Mon, 25 Apr 2016 10:02:07 EDT //www.koonmotors.com/releases/2016/04/160425100207.htm //www.koonmotors.com/releases/2016/03/160301174801.htm New research suggests that Helicobacter pylori (H. pylori) infection of the stomach, which occurs in about half of the world's population and can cause peptic ulcers and stomach cancer in minority of cases, may help protect against an allergic disorder of the esophagus condition called eosinophilic esophagitis. Tue, 01 Mar 2016 17:48:01 EST //www.koonmotors.com/releases/2016/03/160301174801.htm //www.koonmotors.com/releases/2016/01/160114110724.htm The gastric pathogen Helicobacter pylori is highly adapted to survival in the human stomach and responsible for the majority of peptic ulcer and gastric cancer cases worldwide. An important survival strategy for the bacterium involves the tight binding to the stomach mucosa, out of reach of the noxious gastric juices. To do so, H. pylori adheres to blood group sugars found on gastric mucus and underlying cells. Scientists provide detailed structural and functional insights into the protein responsible for this interaction. Thu, 14 Jan 2016 11:07:24 EST //www.koonmotors.com/releases/2016/01/160114110724.htm //www.koonmotors.com/releases/2015/07/150721193856.htm Eliminating Helicobacter pylori bacterium -- the main cause of stomach ulcers - with a short course of therapy of two commonly used medicines may help to reduce the risk of gastric cancer, researchers suggest. Tue, 21 Jul 2015 19:38:56 EDT //www.koonmotors.com/releases/2015/07/150721193856.htm //www.koonmotors.com/releases/2015/05/150506182834.htm The ulcer-causing bacterium Helicobacter pylori can directly interact with stomach stem cells, causing the cells to divide more rapidly, according to a new study. The increased cell division was observed in mice, but the findings could explain why H. pylori is a risk factor for gastric cancer in humans, the researchers said. Wed, 06 May 2015 18:28:34 EDT //www.koonmotors.com/releases/2015/05/150506182834.htm //www.koonmotors.com/releases/2014/11/141125124802.htm The bacterium Helicobacter pylori is strongly associated with gastric ulcers and cancer. To combat the infection, researchers developed LipoLLA, a therapeutic nanoparticle that contains linolenic acid, a component in vegetable oils. In mice, LipoLLA was safe and more effective against H. pylori infection than standard antibiotic treatments. Tue, 25 Nov 2014 12:48:02 EST //www.koonmotors.com/releases/2014/11/141125124802.htm //www.koonmotors.com/releases/2014/10/141022103448.htm A painful inflamed lesion on the oral mucosa, which often seems to be burning at the periphery: every third individual has at one point had such a lesion -- an aphthous ulcer. Often they resolve after a brief period of time. In 2 to 10 percent of patients these lesions are recurrent and require medical treatment. Wed, 22 Oct 2014 10:34:48 EDT //www.koonmotors.com/releases/2014/10/141022103448.htm //www.koonmotors.com/releases/2014/07/140717141955.htm Helicobacter pylori infection promotes stomach ulcers and cancer. How H. pylori initially interacts with and irritates gastric tissue is not well understood. A new article now describes that H. pylori rapidly identifies and colonizes sites of minor injuries in the stomach, almost immediately interferes with healing at those injury sites, and so promotes sustained gastric damage. Thu, 17 Jul 2014 14:19:55 EDT //www.koonmotors.com/releases/2014/07/140717141955.htm //www.koonmotors.com/releases/2014/06/140602101211.htm The germ Helicobacter pylori is the cause of most stomach ulcers. It is estimated that 50% of the global population may be infected with H. pylori; however, only 20% of infected people experience symptoms. New evidence suggests that patients treated for the infection developed significant weight gain compared to subjects with untreated H. pylori colonization. Mon, 02 Jun 2014 10:12:11 EDT //www.koonmotors.com/releases/2014/06/140602101211.htm //www.koonmotors.com/releases/2014/02/140225134235.htm Patients were twice as likely to have a diabetic foot ulcer heal within eight weeks when they were treated with a tissue repair drug versus a placebo, according to new research. Foot ulcers are a common complication from diabetes than can lead to hospitalization and lower limb amputation. Tue, 25 Feb 2014 13:42:35 EST //www.koonmotors.com/releases/2014/02/140225134235.htm //www.koonmotors.com/releases/2014/01/140108112656.htm Doctors may soon be able to diagnose stomach ulcers without taking tissue samples from the stomach. Researchers now report to have developed a new, safer and noninvasive diagnostic technique for ulcers. The trick is to make the ulcer-causing bacteria in the gut light up in fluorescent green. Wed, 08 Jan 2014 11:26:56 EST //www.koonmotors.com/releases/2014/01/140108112656.htm //www.koonmotors.com/releases/2013/12/131220200653.htm An international team of researchers have taken a first step towards identifying glycans — sugars attached to proteins — that could help clinicians diagnose gastric cancer before it becomes deadly. Fri, 20 Dec 2013 20:06:53 EST //www.koonmotors.com/releases/2013/12/131220200653.htm //www.koonmotors.com/releases/2013/12/131219142336.htm Researchers have developed an oral vaccine against Helicobacter pylori, the bacteria responsible for peptic ulcers and some forms of gastric cancer, and have successfully tested it in mice. Thu, 19 Dec 2013 14:23:36 EST //www.koonmotors.com/releases/2013/12/131219142336.htm //www.koonmotors.com/releases/2013/09/130925130300.htm Researchers have developed a model that helps scientists and clinicians understand that complex interactions of a type of bacteria that is the leading cause of peptic ulcers. The discovery may inform changes in the ways doctors treat patients. Wed, 25 Sep 2013 13:03:00 EDT //www.koonmotors.com/releases/2013/09/130925130300.htm //www.koonmotors.com/releases/2013/09/130920094405.htm Gut-dwelling bacteria are attracting attention, particularly those associated with human diseases. Helicobacter pylori is found in the stomach of humans, where it may cause chronic gastritis and gastric ulcers, although the majority of infections are asymptomatic. The bacterium has been associated with humans for more than 100,000 years, when it first infected San hunter-gatherers. An international consortium has discovered that the Baka pygmies of Cameroon, another community of hunter-gatherers, have a surprisingly low rate of Helicobacter infection. Fri, 20 Sep 2013 09:44:05 EDT //www.koonmotors.com/releases/2013/09/130920094405.htm //www.koonmotors.com/releases/2013/09/130902101712.htm Helicobacter pylori is a bacterium that establishes a life-long stomach infection in humans, which in some cases can lead to duodenal ulcers or stomach cancer. New research gives us a clearer understanding of how these bacteria can manipulate the human immune system to survive in the mucosal lining of the stomach. Mon, 02 Sep 2013 10:17:12 EDT //www.koonmotors.com/releases/2013/09/130902101712.htm //www.koonmotors.com/releases/2013/05/130507164234.htm Two genome-wide association studies and a subsequent meta-analysis have found that certain genetic variations are associated with susceptibility to Helicobacter pylori, a bacteria that is a major cause of gastritis and stomach ulcers and is linked to stomach cancer, findings that may help explain some of the observed variation in individual risk for H pylori infection. Tue, 07 May 2013 16:42:34 EDT //www.koonmotors.com/releases/2013/05/130507164234.htm //www.koonmotors.com/releases/2013/04/130418162314.htm Numerous epidemiologic studies have shown that a diet high in salt is associated with an increased risk of gastric cancer. Now researchers have shown that high dietary salt combined with infection by the ulcer-causing bacterium Helicobacter pylori greatly increases the risk of cancer. Thu, 18 Apr 2013 16:23:14 EDT //www.koonmotors.com/releases/2013/04/130418162314.htm //www.koonmotors.com/releases/2013/03/130325135355.htm Mice with different naturally occurring stomach bacteria have distinct susceptibilities to disease caused by Helicobacter pylori, the well-known cause of ulcers in humans, according to a new study. This is the first study to document (in mice) that the presence of certain bacteria in the stomach microbiota can prevent pathology from H. pylori. Mon, 25 Mar 2013 13:53:55 EDT //www.koonmotors.com/releases/2013/03/130325135355.htm //www.koonmotors.com/releases/2013/03/130312134733.htm Half of the world's human population is infected with the stomach bacteria called Helicobacter pylori, yet it causes disease in only about 10 percent of those infected. Other bacteria living in the stomach may be a key factor in whether or not H. pylori causes disease, according to a new study. Tue, 12 Mar 2013 13:47:33 EDT //www.koonmotors.com/releases/2013/03/130312134733.htm //www.koonmotors.com/releases/2013/02/130208182829.htm A stomach bacterium believed to cause health problems such as gastritis, ulcers, and gastric cancer may play a dual role by balancing the stomach's ecosystem and controlling body weight and glucose tolerance, according to immunologists. Fri, 08 Feb 2013 18:28:29 EST //www.koonmotors.com/releases/2013/02/130208182829.htm //www.koonmotors.com/releases/2012/12/121220143709.htm A drug for ischemic strokes may also treat tuberculosis and ulcers. New research shows the compound, ebselen, to inhibit the thioredoxin reductase system in bacteria, including Helicobacter pylori and Mycobacterium tuberculosis. Thu, 20 Dec 2012 14:37:09 EST //www.koonmotors.com/releases/2012/12/121220143709.htm //www.koonmotors.com/releases/2011/11/111121151544.htm Without the ability to swim to their targets in the stomach, ulcer-causing bacteria do not cause the inflammation of the stomach lining that leads to ulcers and stomach cancer, according to a new study. Mon, 21 Nov 2011 15:15:44 EST //www.koonmotors.com/releases/2011/11/111121151544.htm //www.koonmotors.com/releases/2011/10/111026091012.htm What’s crucial for a diabetic’s foot sore to heal is that the ulcer is superficial, blood circulation is normal, and the person has had diabetes for short time. This is shown in a large diabetes study regarding foot ulcers, carried out in Sweden. Wed, 26 Oct 2011 09:10:12 EDT //www.koonmotors.com/releases/2011/10/111026091012.htm //www.koonmotors.com/releases/2011/10/111025091541.htm In an experiment on rats, European researchers have proved that eating strawberries reduces the harm that alcohol can cause to the stomach mucous membrane. The study may contribute to improving the treatment of stomach ulcers. Tue, 25 Oct 2011 09:15:41 EDT //www.koonmotors.com/releases/2011/10/111025091541.htm //www.koonmotors.com/releases/2011/10/111017170829.htm Bacteria that cause stomach inflammation and ulcers were not detectable in tissue from inflamed and enlarged adenoids in children, according to a new report. Mon, 17 Oct 2011 17:08:29 EDT //www.koonmotors.com/releases/2011/10/111017170829.htm //www.koonmotors.com/releases/2011/07/110712162824.htm Among nursing home residents at high risk for pressure ulcers, black residents had higher prevalence rates than white residents from 2003 through 2008, with the disparity largely related to the higher rates among nursing homes that disproportionately serve black residents, according to a new study. Tue, 12 Jul 2011 16:28:24 EDT //www.koonmotors.com/releases/2011/07/110712162824.htm //www.koonmotors.com/releases/2011/05/110523124406.htm Researchers report that in patients with peptic ulcer bleeding in whom endoscopy failed to control the bleeding, transarterial embolization is a safe procedure which reduces the need for surgery without increasing overall mortality and is associated with few complications. Mon, 23 May 2011 12:44:06 EDT //www.koonmotors.com/releases/2011/05/110523124406.htm //www.koonmotors.com/releases/2011/05/110522141547.htm The stomach bacteria responsible for ulcers could also play a role in the development of Parkinson's disease according to new research. Sun, 22 May 2011 14:15:47 EDT //www.koonmotors.com/releases/2011/05/110522141547.htm //www.koonmotors.com/releases/2011/05/110505181539.htm DNA from Helicobacter pylori, a common stomach bacteria, minimizes the effects of colitis in mice, according to a new study. Thu, 05 May 2011 18:15:39 EDT //www.koonmotors.com/releases/2011/05/110505181539.htm //www.koonmotors.com/releases/2011/02/110224121905.htm Researchers have identified a strain of probiotic bacteria that may be useful in treating ulcers caused by Helicobacter pylori. Thu, 24 Feb 2011 12:19:05 EST //www.koonmotors.com/releases/2011/02/110224121905.htm //www.koonmotors.com/releases/2010/11/101101130141.htm Helicobacter pylori, a common stomach bacterium, reduced the severity of inflammation of the colon caused by Salmonella in mice, according to new research. Mon, 01 Nov 2010 13:01:41 EDT //www.koonmotors.com/releases/2010/11/101101130141.htm //www.koonmotors.com/releases/2010/10/101016080016.htm Helicobacter pylori, the bacterium largely associated with gastritis and peptic ulcers in humans, may invade and replicate in gastric epithelial cells say researchers from China. This discovery disputes prior views of H. pylori as a noninvasive pathogen and could offer significant insight into its ability to resist antibacterial therapy and its biological life cycle as a whole. Sat, 16 Oct 2010 08:00:16 EDT //www.koonmotors.com/releases/2010/10/101016080016.htm //www.koonmotors.com/releases/2010/10/101013122742.htm A new material similar to that used by the US military to treat traumatic injuries is showing promise as the next novel treatment for bleeding ulcers, a condition that commonly affects up to 15 percent of adults, according to new research. Wed, 13 Oct 2010 12:27:42 EDT //www.koonmotors.com/releases/2010/10/101013122742.htm //www.koonmotors.com/releases/2010/08/100802101622.htm People suffering from diabetes-related foot ulcers show different rates of healing according to the way they cope and their psychological state of mind, according to new research by a health psychologist. Mon, 02 Aug 2010 10:16:22 EDT //www.koonmotors.com/releases/2010/08/100802101622.htm //www.koonmotors.com/releases/2010/06/100628075752.htm Researchers have identified cells in the immune system that react to the stomach ulcer bacterium Helicobacter pylori, one of the risk factors for the development of stomach cancer. This discovery could lead to faster diagnosis and treatment as well as a better prognosis for patients with stomach cancer. Mon, 28 Jun 2010 07:57:52 EDT //www.koonmotors.com/releases/2010/06/100628075752.htm //www.koonmotors.com/releases/2010/06/100616102850.htm An international team of researchers has sequenced the genome of an Amerindian strain of the gastric bug Helicobacter pylori, confirming the out-of-Africa migration of this bacterial stowaway to the New World. Experiments in animals have highlighted how specific genes in the bacterial strain may be crucial to the onset of inflammation and disease. Wed, 16 Jun 2010 10:28:50 EDT //www.koonmotors.com/releases/2010/06/100616102850.htm //www.koonmotors.com/releases/2010/05/100507101840.htm A research team from South Korea evaluated the treatment outcome of Helicobacter pylori (H. pylori)-negative low-grade gastric mucosa associated lymphoid tissue (MALT) lymphoma patients to offer therapeutic guidelines for such patients. Their results showed that eradication therapy may be offered as an initial treatment option even in cases of localized H. pylori-negative gastric MALT lymphoma. Fri, 07 May 2010 10:18:40 EDT //www.koonmotors.com/releases/2010/05/100507101840.htm //www.koonmotors.com/releases/2010/03/100301163534.htm Young children in developing countries are infected at an early age with the bacterium Helicobacter pylori, which can cause peptic ulcers and stomach cancer. New findings show that childrens´ immune responses help in fighting the bacteria. In addition, breastfeeding and better hygiene appear to protect against infection. Mon, 01 Mar 2010 16:35:34 EST //www.koonmotors.com/releases/2010/03/100301163534.htm //www.koonmotors.com/releases/2010/02/100209182934.htm Helicobacter pylori (H. pylori) colonize the human stomach and present genetic mechanisms to evade the host immune response allowing their persistence in this habitat for years. A study involving 130 H. pylori strains isolated from patients living in different Chilean cities revealed that, nearly half of them carry the hopE and hopV genes. The results suggest that these genes can be turned on and off, and are likely to be involved in avoiding immune recognition. Tue, 09 Feb 2010 18:29:34 EST //www.koonmotors.com/releases/2010/02/100209182934.htm //www.koonmotors.com/releases/2010/01/100125094639.htm Despite a strong response from our immune defence, the body is unable to rid itself of the bacterium Helicobacter pylori. One reason for this is that this bacterium encourages elements of the immune response to remain in tissue, activating the wrong immune cells. New research results are paving the way for a future vaccine. Mon, 25 Jan 2010 09:46:39 EST //www.koonmotors.com/releases/2010/01/100125094639.htm