//www.koonmotors.com/news/health_medicine/std/ Sexually transmitted diseases. Read the latest medical research on STDs including prevention and new treatments. en-us Fri, 08 Sep 2023 17:15:25 EDT Fri, 08 Sep 2023 17:15:25 EDT 60 //www.koonmotors.com/images/scidaily-logo-rss.png//www.koonmotors.com/news/health_medicine/std/ For more science news, visit ScienceDaily. //www.koonmotors.com/releases/2023/09/230907105827.htm Herpes is not only unpleasant but it can, in some cases, also have dangerous complications and life-threatening consequences. A research team has now introduced a completely new approach for treating herpes. Their method is based on the inhibition of an enzyme that is needed for the release of newly formed virus particles from infected cells. Thu, 07 Sep 2023 10:58:27 EDT //www.koonmotors.com/releases/2023/09/230907105827.htm //www.koonmotors.com/releases/2023/09/230905124929.htm A new international study has shown mpox (formerly known as monkeypox) infections to be less severe among those who are vaccinated or had a previous infection in 2022, underlining the importance and effectiveness of vaccination. Tue, 05 Sep 2023 12:49:29 EDT //www.koonmotors.com/releases/2023/09/230905124929.htm //www.koonmotors.com/releases/2023/08/230817164016.htm A single injection of a novel CRISPR gene-editing treatment safely and efficiently removes SIV -- a virus related to the AIDS-causing agent HIV -- from the genomes of non-human primates, scientists now report. The groundbreaking work complements previous experiments as the basis for the first-ever clinical trial of an HIV gene-editing technology in human patients, which was authorized by the Food and Drug Administration (FDA) in 2022. Thu, 17 Aug 2023 16:40:16 EDT //www.koonmotors.com/releases/2023/08/230817164016.htm //www.koonmotors.com/releases/2023/08/230810110414.htm Researchers created a germ-free mouse model to evaluate the role of the microbiome in the infection, replication, and pathogenesis of HIV and the Epstein-Barr virus, the virus that can cause mononucleosis and other serious diseases. Thu, 10 Aug 2023 11:04:14 EDT //www.koonmotors.com/releases/2023/08/230810110414.htm //www.koonmotors.com/releases/2023/08/230810110313.htm A study has identified a new pathway that human immune deficiency virus (HIV) uses to enter the nucleus of a healthy cell, where it can then replicate and go on to invade other cells. Thu, 10 Aug 2023 11:03:13 EDT //www.koonmotors.com/releases/2023/08/230810110313.htm //www.koonmotors.com/releases/2023/08/230802132005.htm A study on almost four thousand people of African descent has identified a gene that acts as natural defense against HIV by limiting its replication in certain white blood cells. This research paves the way for new treatment strategies and underscores the importance of studying diverse ancestral populations to better address their specific medical needs and global health disparities. Wed, 02 Aug 2023 13:20:05 EDT //www.koonmotors.com/releases/2023/08/230802132005.htm //www.koonmotors.com/releases/2023/06/230622120820.htm The herpes simplex virus-1 can sometimes cause a dangerous brain infection. Combining an anti-inflammatory and an antiviral could help in these cases, report scientists. Thu, 22 Jun 2023 12:08:20 EDT //www.koonmotors.com/releases/2023/06/230622120820.htm //www.koonmotors.com/releases/2023/05/230509122018.htm New research found that people living with HIV that have had pulmonary tuberculosis had broader and more potent HIV antibody responses and differences in HIV sequences predicted to be antibody resistant as compared to those without suspected or documented tuberculosis. Tue, 09 May 2023 12:20:18 EDT //www.koonmotors.com/releases/2023/05/230509122018.htm //www.koonmotors.com/releases/2023/05/230502155419.htm Gene-editing therapy aimed at two targets -- HIV-1, the virus that causes AIDS, and CCR5, the co-receptor that helps the virus get into cells -- can effectively eliminate HIV infection, new research shows. The study combines a dual gene-editing strategy with antiretroviral drugs to cure animals of HIV-1. Tue, 02 May 2023 15:54:19 EDT //www.koonmotors.com/releases/2023/05/230502155419.htm //www.koonmotors.com/releases/2023/05/230501112154.htm A new study on herpes infections of the eye helps shed light on the question of viral reinfections by identifying a key protein involved in viral reinfections that could be targeted by antiviral drugs. Mon, 01 May 2023 11:21:54 EDT //www.koonmotors.com/releases/2023/05/230501112154.htm //www.koonmotors.com/releases/2023/03/230327114935.htm 开发治疗可能有一天完全rid the body of HIV infection, scientists have long sought to identify all of the places that the virus can hide its genetic code. Now, in a study using blood samples from men and women with HIV on long-term suppressive therapy, a team of scientists reports new evidence that one such stable reservoir of HIV genomes can be found in circulating white blood cells called monocytes. Mon, 27 Mar 2023 11:49:35 EDT //www.koonmotors.com/releases/2023/03/230327114935.htm //www.koonmotors.com/releases/2023/03/230324093449.htm MitoQ, a mitochondrial antioxidant that is available to the public as a diet supplement, was found in a mouse study to reverse the detrimental effects that HIV and antiretroviral therapy (ART) have on mitochondria in the brain, heart, aorta, lungs, kidney and liver. Fri, 24 Mar 2023 09:34:49 EDT //www.koonmotors.com/releases/2023/03/230324093449.htm //www.koonmotors.com/releases/2023/03/230316114046.htm The human immunodeficiency virus HIV-1 is able to infect various tissues in humans. Once inside the cells, the virus integrates its genome into the cellular genome and establishes persistent infections. The role of the structure and organization of the host genome in HIV-1 infection is not well understood. Using a cell culture model based on brain immune microglia cells, an international research team has now defined the insertion patterns of HIV-1 in the genome of microglia cells. Thu, 16 Mar 2023 11:40:46 EDT //www.koonmotors.com/releases/2023/03/230316114046.htm //www.koonmotors.com/releases/2023/03/230314110730.htm Atopic dermatitis skin lesions and the lesions produced by infectious complications of the disease look so similar that it makes it impossible for patients to spot the difference and know when to visit their doctor for treatment. But an AI-powered mobile app developed by dermatologists now puts the power of diagnosis in the hands of patients. Tue, 14 Mar 2023 11:07:30 EDT //www.koonmotors.com/releases/2023/03/230314110730.htm //www.koonmotors.com/releases/2023/02/230228113747.htm A research team has shown that, as early as the first days of infection, HIV is able to create reservoirs where it will hide and persist during antiretroviral therapy. Tue, 28 Feb 2023 11:37:47 EST //www.koonmotors.com/releases/2023/02/230228113747.htm //www.koonmotors.com/releases/2023/02/230224165409.htm Haematopoietic stem cell transplantation for the treatment of severe blood cancers is the only medical intervention that has cured two people living with HIV in the past. An international group of physicians and researchers has now identified another case in which HIV infection has been shown to be cured in the same way. The successful healing process of this third patient was for the first time characterized in great detail virologically and immunologically over a time span of ten years. 星期五,2023年2月24日16:54:09 EST //www.koonmotors.com/releases/2023/02/230224165409.htm //www.koonmotors.com/releases/2023/01/230110151022.htm In a rigorous new study virologists are describing an against-the-grain discovery that is a potential game changer in the field. It has the potential to show the way forward for HIV cure research. Tue, 10 Jan 2023 15:10:22 EST //www.koonmotors.com/releases/2023/01/230110151022.htm //www.koonmotors.com/releases/2022/11/221130114527.htm Medical researchers found a new way genetics influences the body's antiviral response by studying a life-threatening disease caused by a common virus: herpes simplex virus 1 (HSV-1). Wed, 30 Nov 2022 11:45:27 EST //www.koonmotors.com/releases/2022/11/221130114527.htm //www.koonmotors.com/releases/2022/11/221128201747.htm Researchers found that across the U.S., anal cancer incidence and mortality rates increased 1.5-fold in men and women over 50 years old. However, the most prominent increase -- more than two-fold -- occurred among people over 50 years of age living in the Midwestern and Southeastern states. Mon, 28 Nov 2022 20:17:47 EST //www.koonmotors.com/releases/2022/11/221128201747.htm //www.koonmotors.com/releases/2022/11/221122111356.htm Though antiretroviral therapy has made HIV a manageable disease, people living with HIV often suffer from chronic inflammation. This can put them at an increased risk of developing comorbidities such as cardiovascular disease and neurocognitive dysfunction, impacting the longevity and quality of their lives. Now, a new study explains why chronic inflammation may be happening and how suppression or even eradication of HIV in the body may not resolve it. Tue, 22 Nov 2022 11:13:56 EST //www.koonmotors.com/releases/2022/11/221122111356.htm //www.koonmotors.com/releases/2022/11/221115113924.htm 一些商业耳塞可以执行他ring aids. The result could help a large proportion of people with hearing loss access more affordable sound amplification devices. Tue, 15 Nov 2022 11:39:24 EST //www.koonmotors.com/releases/2022/11/221115113924.htm //www.koonmotors.com/releases/2022/11/221114190621.htm An immune response that likely evolved to help fight infections appears to be the mechanism that drives human immunodeficiency virus (HIV) into a latent state, lurking in cells only to erupt anew, researchers report. Mon, 14 Nov 2022 19:06:21 EST //www.koonmotors.com/releases/2022/11/221114190621.htm //www.koonmotors.com/releases/2022/11/221108120517.htm The type of virus used as a model to study the efficacy of non-neutralizing antibodies against the virus responsible for AIDS has a crucial role to play, according to a new study. Tue, 08 Nov 2022 12:05:17 EST //www.koonmotors.com/releases/2022/11/221108120517.htm //www.koonmotors.com/releases/2022/11/221107114454.htm Investigators analyzed longitudinal samples of cervical and serum biomarker levels for immune activation, before and after subjects acquired HSV-2. They found that altered levels of specific biomarkers in the mucosa and serum were associated with HSV-2 acquisition only, while others overlapped with biomarkers and combinations predictive of HIV-1 acquisition. Mon, 07 Nov 2022 11:44:54 EST //www.koonmotors.com/releases/2022/11/221107114454.htm //www.koonmotors.com/releases/2022/10/221021132741.htm Starting antiretroviral treatment (ART) early in the course of HIV infection when the immune system is stronger results in better long-term health outcomes compared with delaying ART, according to new findings. Fri, 21 Oct 2022 13:27:41 EDT //www.koonmotors.com/releases/2022/10/221021132741.htm //www.koonmotors.com/releases/2022/10/221013194117.htm People with HIV who have moderate immune suppression appear to be at greater risk of severe COVID-19 'breakthrough' infection after vaccination, according to a new study. Thu, 13 Oct 2022 19:41:17 EDT //www.koonmotors.com/releases/2022/10/221013194117.htm //www.koonmotors.com/releases/2022/10/221012132533.htm New research in Zambia finds that children infected with HIV are significantly more likely to do worse in neurological assessments despite having well-controlled HIV disease, suggesting that they may struggle with cognitive and mental health issues. However, the research also indicates that early intervention -- in the form of better nutrition and antiretroviral therapies -- may help close the gap. Wed, 12 Oct 2022 13:25:33 EDT //www.koonmotors.com/releases/2022/10/221012132533.htm //www.koonmotors.com/releases/2022/09/220930090841.htm Certain gut bacteria -- including one that is essential for a healthy gut microbiome -- differ between people who go on to acquire HIV infection compared to those who have not become infected. Fri, 30 Sep 2022 09:08:41 EDT //www.koonmotors.com/releases/2022/09/220930090841.htm //www.koonmotors.com/releases/2022/09/220923121642.htm Creating a mutation that inhibits how the bacterial pathogen Neisseria gonorrhoeae causes gonorrhea, a common sexually transmitted infection, could offer a new way to prevent and treat the disease, according to researchers. Fri, 23 Sep 2022 12:16:42 EDT //www.koonmotors.com/releases/2022/09/220923121642.htm //www.koonmotors.com/releases/2022/09/220921093006.htm The risk of heart attack was about 30% higher with each decade of age as people with HIV got older. However, that risk increased 85% with each decade among people who also have untreated hepatitis C, according to a new analysis of more than 23,000 people receiving HIV treatment in North America. These findings indicate HIV and hepatitis C status, as well as more traditional heart disease risk factors, should be considered to decrease heart attack risk. Wed, 21 Sep 2022 09:30:06 EDT //www.koonmotors.com/releases/2022/09/220921093006.htm //www.koonmotors.com/releases/2022/09/220915104722.htm Cow mucus provides the basis for a synthetic prophylactic gel developed to protect against HIV and herpes transmission. The lubricating gel proved 70 percent effective in lab tests against HIV, and 80 percent effective against herpes. Thu, 15 Sep 2022 10:47:22 EDT //www.koonmotors.com/releases/2022/09/220915104722.htm //www.koonmotors.com/releases/2022/09/220908112457.htm Chlamydia, the leading cause of sexually transmitted bacterial infections, evades detection and elimination inside human cells by use of a cloaking device. But researchers have grasped the hem of that invisibility cloak and now hope they can pull it apart. This evolutionary arms race between the immune system and the pathogen has been going on for millions of years and its parts are very finely tuned. Thu, 08 Sep 2022 11:24:57 EDT //www.koonmotors.com/releases/2022/09/220908112457.htm //www.koonmotors.com/releases/2022/08/220824170139.htm Lessons learned from the public health responses to the HIV and COVID-19 pandemics should help guide the response to the current outbreak of monkeypox, National Institutes of Health experts write in a new editorial. Wed, 24 Aug 2022 17:01:39 EDT //www.koonmotors.com/releases/2022/08/220824170139.htm //www.koonmotors.com/releases/2022/08/220805112004.htm A clinical trial to test whether three proven smoking cessation treatments could also reduce alcohol intake found no differences between the medications, but the rates of behavior change for alcohol consumption and smoking were high in all treatment groups. Results suggest these medications could play an important role to reduce alcohol use and smoking at the same time. Unexpectedly, nicotine replacement therapy performed as well as the prescription drugs varenicline and cytisine. Fri, 05 Aug 2022 11:20:04 EDT //www.koonmotors.com/releases/2022/08/220805112004.htm //www.koonmotors.com/releases/2022/07/220729173148.htm Two common viruses lie dormant in neurons -- herpes simplex virus (HSV), and varicella zoster virus (VZV). Lab models of the human brain show that activation or re-infection of VZV can trigger neuroinflammation and wake up HSV, leading to accumulation of Alzheimer's linked proteins and neural decline. Fri, 29 Jul 2022 17:31:48 EDT //www.koonmotors.com/releases/2022/07/220729173148.htm //www.koonmotors.com/releases/2022/07/220727110255.htm Scientists described how their use of cutting-edge technology revealed new insights into cellular reservoirs of HIV and what those observations could mean for the next steps in HIV cure research. Wed, 27 Jul 2022 11:02:55 EDT //www.koonmotors.com/releases/2022/07/220727110255.htm //www.koonmotors.com/releases/2022/07/220721204900.htm An international collaboration of clinicians has identified new clinical symptoms in people infected with monkeypox in the largest case study series to date. Their findings will improve future diagnosis, help to slow the spread of infection and help the international community prioritise the limited global supply of monkeypox vaccines and treatments to communities most at risk. Thu, 21 Jul 2022 20:49:00 EDT //www.koonmotors.com/releases/2022/07/220721204900.htm //www.koonmotors.com/releases/2022/07/220714165814.htm Researchers have shown that treating precancerous anal growths called high-grade squamous intraepithelial lesions (HSILs) in persons living with HIV significantly decreased the progression to anal cancer. Thu, 14 Jul 2022 16:58:14 EDT //www.koonmotors.com/releases/2022/07/220714165814.htm //www.koonmotors.com/releases/2022/07/220701102746.htm HIV has an 'early and substantial' impact on aging in infected people, accelerating biological changes in the body associated with normal aging within just two to three years of infection, according to new research. Fri, 01 Jul 2022 10:27:46 EDT //www.koonmotors.com/releases/2022/07/220701102746.htm //www.koonmotors.com/releases/2022/06/220630164700.htm The crystal structure of a human endogenous reverse transcriptase has similarities to HIV reverse transcriptase, a well-known tractable drug target, which will help design drugs to treat cancer and other diseases, according to a study co-authored by a Rutgers researcher. Thu, 30 Jun 2022 16:47:00 EDT //www.koonmotors.com/releases/2022/06/220630164700.htm //www.koonmotors.com/releases/2022/06/220613111951.htm A new study offers a new and unique treatment for AIDS which may be developed into a vaccine or a one-time treatment for patients with HIV. Mon, 13 Jun 2022 11:19:51 EDT //www.koonmotors.com/releases/2022/06/220613111951.htm //www.koonmotors.com/releases/2022/06/220607120901.htm A new study finds that people with HIV have a higher rate of breakthrough COVID-19 infections after vaccination, compared to people without HIV. Tue, 07 Jun 2022 12:09:01 EDT //www.koonmotors.com/releases/2022/06/220607120901.htm //www.koonmotors.com/releases/2022/05/220524110713.htm The cornea -- the transparent protective outer layer of the eye critical to helping us see -- produces a delicate and limited immune response to fight infections without damaging our vision, according to a new study. Tue, 24 May 2022 11:07:13 EDT //www.koonmotors.com/releases/2022/05/220524110713.htm //www.koonmotors.com/releases/2022/05/220517112254.htm A new study partially explains why tuberculosis infections easily take hold in the host's lungs and suggests that boosting T cell response is key to creating a therapy that can shut down the infection at its onset. Tue, 17 May 2022 11:22:54 EDT //www.koonmotors.com/releases/2022/05/220517112254.htm //www.koonmotors.com/releases/2022/05/220513103513.htm Life-like organ replicas -- so-called 3D organoids -- are a good way to research disease processes. A team has now presented a kind of blueprint for such a model of the cervix. Fri, 13 May 2022 10:35:13 EDT //www.koonmotors.com/releases/2022/05/220513103513.htm //www.koonmotors.com/releases/2022/05/220503141344.htm Researchers contribute to a better understanding of HIV-1 latency: implications for the development of new therapeutic strategies. Tue, 03 May 2022 14:13:44 EDT //www.koonmotors.com/releases/2022/05/220503141344.htm //www.koonmotors.com/releases/2022/04/220401160537.htm 科学家们利用新进展CRISPR gene-editing technology to uncover new biology that could lead to longer-lasting treatments and new therapeutic strategies for Human Immunodeficiency Virus (HIV). Fri, 01 Apr 2022 16:05:37 EDT //www.koonmotors.com/releases/2022/04/220401160537.htm //www.koonmotors.com/releases/2022/03/220331151530.htm A new study uses next-generation gene sequencing to get a clearer read on the community of viruses present in vaginal microbiome samples and its implication for the development of cervical cancer. Thu, 31 Mar 2022 15:15:30 EDT //www.koonmotors.com/releases/2022/03/220331151530.htm //www.koonmotors.com/releases/2022/03/220325185909.htm Thanks to antiretroviral therapy, HIV infection is no longer the life sentence it once was. But despite the effectiveness of drugs to manage and treat the virus, it can never be fully eliminated from the human body, lingering in some cells deep in different human tissues where it goes unnoticed by the immune system. Now, new research by immunologists reveals a possible answer to the mystery of why infected people can't get rid of HIV altogether. Fri, 25 Mar 2022 18:59:09 EDT //www.koonmotors.com/releases/2022/03/220325185909.htm //www.koonmotors.com/releases/2022/03/220317125803.htm Researchers have found that there are nearly twice as many men with cancer among men living with HIV (MLWH) compared to men who do not have the human immunodeficiency virus. The rates of cancer are even higher in men with symptomatic HIV. Thu, 17 Mar 2022 12:58:03 EDT //www.koonmotors.com/releases/2022/03/220317125803.htm //www.koonmotors.com/releases/2022/03/220308115640.htm Sexual partnerships between individuals from different communities may help explain why some community-based HIV prevention efforts were moderately effective, shows a new study. Tue, 08 Mar 2022 11:56:40 EST //www.koonmotors.com/releases/2022/03/220308115640.htm //www.koonmotors.com/releases/2022/03/220303191502.htm Study shows that L. iners has unique nutritional requirements that distinguish it from L. crispatus, potentially allowing it to be targeted using novel therapeutic strategies. Thu, 03 Mar 2022 19:15:02 EST //www.koonmotors.com/releases/2022/03/220303191502.htm //www.koonmotors.com/releases/2022/02/220224112615.htm Infections with several pathogens simultaneously increase the risk of cervical cancer, according to a new study conducted on artificial 3D tissue models. Thu, 24 Feb 2022 11:26:15 EST //www.koonmotors.com/releases/2022/02/220224112615.htm //www.koonmotors.com/releases/2022/02/220203161215.htm 新的研究揭示了寿命和轨迹tion of the cells that are responsible for producing HIV, preventing its eradication. Understanding the cells' dynamics may help scientists develop new ways to reduce their number with the ultimate goal of curing HIV infection. Thu, 03 Feb 2022 16:12:15 EST //www.koonmotors.com/releases/2022/02/220203161215.htm //www.koonmotors.com/releases/2022/01/220125093014.htm 一项新的研究打开了一扇门的新方法to attacking herpesviruses. The study demonstrated that targeting 2 metal ion-dependent enzymes of human herpesviruses with 2 compounds, AK-157 and AK-166, can inhibit the replication of the virus. The finding provides new opportunities to developing agents against herpesviruses. Tue, 25 Jan 2022 09:30:14 EST //www.koonmotors.com/releases/2022/01/220125093014.htm //www.koonmotors.com/releases/2022/01/220113151342.htm A new study provides compelling evidence of causality between Epstein-Barr virus and multiple sclerosis. It suggests that most MS cases could be prevented by stopping EBV infection, and that targeting EBV could lead to the discovery of a cure for MS. Thu, 13 Jan 2022 15:13:42 EST //www.koonmotors.com/releases/2022/01/220113151342.htm //www.koonmotors.com/releases/2022/01/220112093902.htm New research in mice suggests that adding a certain type of tomato concentrate to the diet can reduce the intestinal inflammation that is associated with HIV. Left untreated, intestinal inflammation can accelerate arterial disease, which in turn can lead to heart attack and stroke. Wed, 12 Jan 2022 09:39:02 EST //www.koonmotors.com/releases/2022/01/220112093902.htm //www.koonmotors.com/releases/2022/01/220105094341.htm Researchers have discovered details of how proteins produced by oral epithelial cells protect humans against viruses entering the body through the mouth. They also found that oral bacteria can suppress the activity of these cells, increasing vulnerability to infection. Wed, 05 Jan 2022 09:43:41 EST //www.koonmotors.com/releases/2022/01/220105094341.htm //www.koonmotors.com/releases/2021/12/211208204211.htm A serendipitous conversation and 'treasure trove' of frozen stool samples from early in the HIV/AIDS pandemic shed light on the role of the microbiome in disease prevention. The study is the first to link the composition of the gut microbiome before infection to HIV susceptibility and progression. Wed, 08 Dec 2021 20:42:11 EST //www.koonmotors.com/releases/2021/12/211208204211.htm //www.koonmotors.com/releases/2021/12/211201162038.htm With a shortage of mental health professionals, an international team trained nurses to treat clinically depressed HIV-positive people in South Africa -- the HIV/AIDS capital of the world. Wed, 01 Dec 2021 16:20:38 EST //www.koonmotors.com/releases/2021/12/211201162038.htm