//www.koonmotors.com/news/health_medicine/skin_cancer/ Learn about skin cancer signs, symptoms and prevention. Read the latest medical research on skin cancer types, skin care and skin cancer treatment options. en-us Sun, 10 Sep 2023 21:16:10 EDT Sun, 10 Sep 2023 21:16:10 EDT 60 //www.koonmotors.com/images/scidaily-logo-rss.png//www.koonmotors.com/news/health_medicine/skin_cancer/ For more science news, visit ScienceDaily. //www.koonmotors.com/releases/2023/08/230831121720.htm A new study examines why people living in Atlantic regions are more at-risk for developing melanoma than other Canadians, providing lessons on skin cancer prevention for the whole country. To find out why, the researchers compared UV exposure and behaviours among different groups in Atlantic Canada based on income, education, and gender, among other factors. Thu, 31 Aug 2023 12:17:20 EDT //www.koonmotors.com/releases/2023/08/230831121720.htm //www.koonmotors.com/releases/2023/08/230810110140.htm The administration of ranolazine, a drug currently used to treat heart conditions, improves the efficacy of current therapies for melanoma, in mouse models of this disease. Thu, 10 Aug 2023 11:01:40 EDT //www.koonmotors.com/releases/2023/08/230810110140.htm //www.koonmotors.com/releases/2023/07/230727144130.htm Investigators have designed an innovative RNA-based strategy to activate dendritic cells--which play a key role in immune response -- that eradicated tumors and prevented their recurrence in mouse models of melanoma. The findings suggest that the approach has the potential to be effective against tumors that have already spread to other parts of the body and against different cancer types. Cancer cells employ strategies to switch off various stages of the cancer-immunity cycle, the process by which dendritic cells educate T cells to kill cancer cells. This immunosuppressive environment that impedes activation of cancer-killing T cells allows tumors to grow, say the researchers. Thu, 27 Jul 2023 14:41:30 EDT //www.koonmotors.com/releases/2023/07/230727144130.htm //www.koonmotors.com/releases/2023/07/230726112536.htm 虽然罕见,黏膜黑色素瘤在人类身上瞧w survival rate. It has been difficult to investigate due to a lack of similar cancers in animals for study. Researchers explored a protein common to human and canine mucosal melanoma. The protein seems to be what makes this cancer so problematic, as it mobilizes the cancer cells, allowing them to spread. Researchers hope that eliminating this protein could lead to a potential treatment. Wed, 26 Jul 2023 11:25:36 EDT //www.koonmotors.com/releases/2023/07/230726112536.htm //www.koonmotors.com/releases/2023/07/230705142949.htm New research has helped explain how melanoma evades the immune system and may guide the discovery of future therapies for the disease. Wed, 05 Jul 2023 14:29:49 EDT //www.koonmotors.com/releases/2023/07/230705142949.htm //www.koonmotors.com/releases/2023/07/230705115136.htm A new vaccine boosts the response of engineered CAR-T cells and helps the immune system generate T cells that target other tumor antigens. The researchers found this approach made it more likely that a tumor can be eradicated in mice. Wed, 05 Jul 2023 11:51:36 EDT //www.koonmotors.com/releases/2023/07/230705115136.htm //www.koonmotors.com/releases/2023/06/230626164211.htm Scientists have identified potential new biomarkers that could indicate how someone diagnosed with metastatic melanoma will respond to immunotherapy treatment. Mon, 26 Jun 2023 16:42:11 EDT //www.koonmotors.com/releases/2023/06/230626164211.htm //www.koonmotors.com/releases/2023/06/230623161126.htm B cells are thought to play a critical role in innate and adaptive immunity, but their exact role in anti-tumor immunity remains unknown. Researchers with expertise in immunology collaborated with experts in dermatology to further understand the role of B cells and identify a subset of cells that may play a critical role. Fri, 23 Jun 2023 16:11:26 EDT //www.koonmotors.com/releases/2023/06/230623161126.htm //www.koonmotors.com/releases/2023/05/230531150214.htm Overall survival for patients with melanoma that has spread to the brain is only four to six months. Immunotherapies, which harness the power of the immune system to attack cancer cells, have garnered excitement in recent years for their potential to revolutionize the treatment of metastatic melanomas, but results from early clinical studies indicate that the prognosis for most patients remains poor. Now, scientists have integrated multiple therapeutic approaches to more effectively target melanoma in the brain. In preclinical studies, the scientists successfully activated immune responses in sophisticated mouse models that mimic human settings. Wed, 31 May 2023 15:02:14 EDT //www.koonmotors.com/releases/2023/05/230531150214.htm //www.koonmotors.com/releases/2023/03/230330122805.htm White blood cells called neutrophils have an unappreciated role in eradicating solid tumors, according to a surprise discovery. Thu, 30 Mar 2023 12:28:05 EDT //www.koonmotors.com/releases/2023/03/230330122805.htm //www.koonmotors.com/releases/2023/03/230328145453.htm Cancer-associated fibroblasts (CAFs) are key factors in the tumor microenvironment, which have been implicated in cancer cell progression. It has also been reported that vesicles called exosomes produced by these CAFs play an important role in cancer progression. A research group investigated the effect of CAF-derived exosomes on the growth of malignant melanoma cells. They found that CAF-derived exosomes express CD9 and CD63 transmembrane proteins, and that the CD9-positive exosomes may inhibit the growth of malignant melanoma cells. Tue, 28 Mar 2023 14:54:53 EDT //www.koonmotors.com/releases/2023/03/230328145453.htm //www.koonmotors.com/releases/2023/02/230216161137.htm 癌症免疫疗法包括使用激活T cells to destroy tumors, but it doesn't work for all patients. Researchers have discovered that a kind of dendritic cell is crucial for determining the effectiveness of immunotherapy. The discovery could lead to new ways to extend the benefits of immunotherapy to more patients. Thu, 16 Feb 2023 16:11:37 EST //www.koonmotors.com/releases/2023/02/230216161137.htm //www.koonmotors.com/releases/2023/01/230123123243.htm Researchers have identified a relatively natural way to increase the numbers and antitumor activities of TILs. A team demonstrates how L-fucose, a nontoxic dietary plant sugar that is enriched in red and brown seaweeds, can increase TILs, promote antitumor immunity and improve the efficacy of immunotherapy. Mon, 23 Jan 2023 12:32:43 EST //www.koonmotors.com/releases/2023/01/230123123243.htm //www.koonmotors.com/releases/2023/01/230109112703.htm New research has identified a protein that makes melanoma, the most serious type of skin cancer, more aggressive by giving cancer cells the ability to change the shape of their nucleus -- a characteristic which allows the cells to migrate and spread around the body. Mon, 09 Jan 2023 11:27:03 EST //www.koonmotors.com/releases/2023/01/230109112703.htm //www.koonmotors.com/releases/2023/01/230109112555.htm Fewer cases of melanoma were observed among regular users of vitamin D supplements than among non-users, a new study finds. People taking vitamin D supplements regularly also had a considerably lower risk of skin cancer, according to estimates by experienced dermatologists. The study included nearly 500 people with an increased risk of skin cancer. Mon, 09 Jan 2023 11:25:55 EST //www.koonmotors.com/releases/2023/01/230109112555.htm //www.koonmotors.com/releases/2022/12/221221090609.htm Researchers have used artificial DNA to target and kill cancer cells in a completely new way. The method was effective in lab tests against human cervical cancer- and breast cancer-derived cells, and against malignant melanoma cells from mice. The team created a pair of chemically synthesized, hairpin-shaped, cancer-killing DNA. When the DNA pairs were injected into cancer cells, they connected to microRNA (miRNA) molecules that are overproduced in certain cancers. Once connected to the miRNA, they unraveled and joined together, forming longer chains of DNA which triggered an immune response. This response not only killed the cancer cells but prevented further growth of cancerous tissue. This method is different from conventional anticancer drug treatments and is hoped to bring about a new era of drug development. Wed, 21 Dec 2022 09:06:09 EST //www.koonmotors.com/releases/2022/12/221221090609.htm //www.koonmotors.com/releases/2022/12/221216131004.htm A new study examined the combination of the common immunotherapy drug pembrolizumab (Keytruda) with all-trans retinoic acid (ATRA), a chemotherapy drug that targets myeloid-derived suppressor cells. Researchers found that the drug combination is effective, with an overall response rate of 71%. Fifty percent of patients experienced a complete response, and the one-year overall survival rate was 80%. Fri, 16 Dec 2022 13:10:04 EST //www.koonmotors.com/releases/2022/12/221216131004.htm //www.koonmotors.com/releases/2022/12/221207183650.htm A patient's own immune cells, multiplied into an army of billions of immune cells in a lab, can be used as a living medicine against metastatic melanoma, an aggressive form of skin cancer, as the TIL trial has shown. The TIL trial is the world's first comparative phase 3 trial looking into the effect of T cell therapy in melanoma, and solid tumors in general. Wed, 07 Dec 2022 18:36:50 EST //www.koonmotors.com/releases/2022/12/221207183650.htm //www.koonmotors.com/releases/2022/11/221128101221.htm Researchers have identified a new method for scheduling radiation therapy that could be as much as 22 percent more effective at killing cancer cells than current standard radiation treatment regimens. Mon, 28 Nov 2022 10:12:21 EST //www.koonmotors.com/releases/2022/11/221128101221.htm //www.koonmotors.com/releases/2022/10/221031134034.htm Researchers have developed and validated a machine learning--based method to predict which patients with early-stage melanoma are most likely to experience a cancer recurrence. Mon, 31 Oct 2022 13:40:34 EDT //www.koonmotors.com/releases/2022/10/221031134034.htm //www.koonmotors.com/releases/2022/10/221031104428.htm A new way of reprogramming our immune cells to shrink or kill off cancer cells has been shown to work in the otherwise hard to treat and devastating skin cancer, melanoma. The discovery demonstrates a new way to clear early stage pre-cancerous and even late-stage tumor cells. Mon, 31 Oct 2022 10:44:28 EDT //www.koonmotors.com/releases/2022/10/221031104428.htm //www.koonmotors.com/releases/2022/09/220928113017.htm A clinical trial showed a remarkable 20 percent advantage in the two-year overall survival rate for people with advanced melanoma who first received immunotherapy (72 percent survival rate) versus those who initially got targeted therapies (52 percent survival rate). Progression-free survival, where the cancer is stable or improving, was also trending in favor of those who started on immunotherapy. Wed, 28 Sep 2022 11:30:17 EDT //www.koonmotors.com/releases/2022/09/220928113017.htm //www.koonmotors.com/releases/2022/09/220922103159.htm The advent of small-molecule targeted therapies, a decade ago, revolutionized the treatment of metastatic melanoma, provided that the tumors carry the mutations to respond to these treatments. However, despite a remarkable initial response that can be seen in a majority of patients, most of them will undergo relapse even after spectacular initial responses. These relapses are due to 'dormant' persistent cells, unresponsive to treatment. Thu, 22 Sep 2022 10:31:59 EDT //www.koonmotors.com/releases/2022/09/220922103159.htm //www.koonmotors.com/releases/2022/09/220920115612.htm Scientists have shown how tumor cells evade immunotherapy by generating unique, temporary cell-in-cell structures, where the inner cells remain in tact and can return to single tumor cells. Tue, 20 Sep 2022 11:56:12 EDT //www.koonmotors.com/releases/2022/09/220920115612.htm //www.koonmotors.com/releases/2022/09/220920100813.htm Researchers have deciphered a mechanism that enables skin cancer to metastasize to the brain and managed to delay the spread of the disease by 60% to 80% using existing treatments. Tue, 20 Sep 2022 10:08:13 EDT //www.koonmotors.com/releases/2022/09/220920100813.htm //www.koonmotors.com/releases/2022/09/220919103203.htm Over the last decade, immune checkpoint blockers, or ICBs, have revolutionized treatment for various advanced cancers, including melanoma, the most aggressive skin cancer that was considered largely incurable not long ago. However, three-fourths of advanced-melanoma patients are resistant to ICBs. Now, researchers reveal a potential target -- using the clinically approved drug ruxolitinib -- to suppress ICB-resistant melanomas. Mon, 19 Sep 2022 10:32:03 EDT //www.koonmotors.com/releases/2022/09/220919103203.htm //www.koonmotors.com/releases/2022/09/220919103122.htm Currently, the only FDA approved biomarker for ICI melanoma treatment is the tumor mutation burden assay, but the mechanisms linking it to ICI remain unclear. However, new research now provides evidence of novel, reliable biomarkers that predict therapy response using advanced computer technology. Mon, 19 Sep 2022 10:31:22 EDT //www.koonmotors.com/releases/2022/09/220919103122.htm //www.koonmotors.com/releases/2022/09/220901135824.htm Researchers have shown that inhibiting a key metabolic enzyme selectively kills melanoma cells and stops tumor growth. The findings could lead to a new class of drugs to selectively treat melanoma, the most severe form of skin cancer. Thu, 01 Sep 2022 13:58:24 EDT //www.koonmotors.com/releases/2022/09/220901135824.htm //www.koonmotors.com/releases/2022/08/220823115454.htm Medical researchers report on their identification of high-risk patients with stage 3A disease and microscopic lymph node metastases who would benefit from adjuvant therapy. Tue, 23 Aug 2022 11:54:54 EDT //www.koonmotors.com/releases/2022/08/220823115454.htm //www.koonmotors.com/releases/2022/08/220815213256.htm Researchers developed a lipid nanoparticle-delivered cancer vaccine against a mouse model of melanoma that specifically targets the lymph system to generate greater potency. They were able to achieve 40% complete response and 100% prevention of new tumor challenges among mice in complete remission. Mon, 15 Aug 2022 21:32:56 EDT //www.koonmotors.com/releases/2022/08/220815213256.htm //www.koonmotors.com/releases/2022/08/220803074917.htm Researchers have identified several proteins involved in the progression of melanoma. One of the proteins -- PDIA6 -- was found to be particularly important for driving malignancy. Experiments with mice showed that melanoma cells with reduced levels of PDIA6 had an impaired ability to metastasize to the lung. The findings could lead to new therapeutic strategies that prevent the spread of melanoma from one part of the body to another. Wed, 03 Aug 2022 07:49:17 EDT //www.koonmotors.com/releases/2022/08/220803074917.htm //www.koonmotors.com/releases/2022/07/220720102530.htm Assessing the thickness of melanoma is difficult, whether done by an experienced dermatologist or a well-trained machine-learning algorithm. A study shows that the algorithm and the dermatologists had an equal success rate in interpreting dermoscopic images. Wed, 20 Jul 2022 10:25:30 EDT //www.koonmotors.com/releases/2022/07/220720102530.htm //www.koonmotors.com/releases/2022/07/220715205758.htm Cancer researchers have completed one of the most comprehensive studies of the cells inside melanoma brain metastases. Fri, 15 Jul 2022 20:57:58 EDT //www.koonmotors.com/releases/2022/07/220715205758.htm //www.koonmotors.com/releases/2022/07/220714145033.htm Most cancer research and available anticancer drugs focus on the impact of DNA and protein alterations that contribute to cancer; however, it is now understood that RNA molecules can also both positively and negatively impact the development of cancer. Researchers now describe how RNA molecules promote the development of melanoma metastasis by impacting anti-tumor microRNA. Thu, 14 Jul 2022 14:50:33 EDT //www.koonmotors.com/releases/2022/07/220714145033.htm //www.koonmotors.com/releases/2022/07/220714091101.htm Exposing humans to ultraviolet radiation to test sunscreen effectiveness should be phased out, according to scientists and cancer experts. Thu, 14 Jul 2022 09:11:01 EDT //www.koonmotors.com/releases/2022/07/220714091101.htm //www.koonmotors.com/releases/2022/06/220623184237.htm A new study reveals important molecular information that could help scientists develop more effective treatment and prevention strategies for a difficult-to-treat form of melanoma skin cancer. Thu, 23 Jun 2022 18:42:37 EDT //www.koonmotors.com/releases/2022/06/220623184237.htm //www.koonmotors.com/releases/2022/06/220621184450.htm A new combination therapy to combat cancer could one day consist of a plant virus and an antibody that activates the immune system's 'natural killer' cells, shows a new study. In mouse models of colon cancer, the combination therapy eliminated all tumors and prevented their recurrence, which in turn resulted in 100% survival. The therapy also increased survival in mouse models of melanoma. Tue, 21 Jun 2022 18:44:50 EDT //www.koonmotors.com/releases/2022/06/220621184450.htm //www.koonmotors.com/releases/2022/06/220615113257.htm Androgen receptor (AR) signaling affects response to BRAF/MEK inhibitor therapy in both males and females with melanoma, researchers have shown. The findings provide a new target to combat therapeutic resistance and one possible answer to why men face a poorer prognosis than women when diagnosed with melanoma. Wed, 15 Jun 2022 11:32:57 EDT //www.koonmotors.com/releases/2022/06/220615113257.htm //www.koonmotors.com/releases/2022/06/220609082034.htm Eating higher levels of fish, including tuna and non-fried fish, appears to be associated with a greater risk of malignant melanoma, suggests a large study of US adults. Thu, 09 Jun 2022 08:20:34 EDT //www.koonmotors.com/releases/2022/06/220609082034.htm //www.koonmotors.com/releases/2022/06/220607121030.htm As people across the globe look forward to longer life expectancies, malignant cancers continue to pose threats to human health. The exploration and development of immunotherapy aims to seek new breakthroughs for the treatment of solid tumors. Although immune checkpoint-based immunotherapy has been shown to have great potential, only a small proportion of patients fully respond to this therapy, and the relevant molecular mechanisms need to be further explored. This delivery method is however complex and inefficient. In a breakthrough development, a team of scientists has formulated a novel vaccine which showed high efficacy in the treatment of solid tumors, achieving complete clearance of solid tumors and inducing long-lasting immune memory. This prevents the relapse of tumor growth that the patient originally presented with and provides immunity against similar tumour types. This was shown through the application of this vaccine on melanoma tumor models. Tue, 07 Jun 2022 12:10:30 EDT //www.koonmotors.com/releases/2022/06/220607121030.htm //www.koonmotors.com/releases/2022/06/220601111820.htm New laboratory research finds that secreted age-induced changes in distant sites such as the lung can effectively reactivate dormant cells and cause them to grow. Wed, 01 Jun 2022 11:18:20 EDT //www.koonmotors.com/releases/2022/06/220601111820.htm //www.koonmotors.com/releases/2022/05/220531111828.htm One powerful way cancer cells defend against tumor-killing immune cells is to load up their cell surface with a protein known as PD-L1. Now a team of researchers has identified a method to degrade tumor cell-surface PD-L1, thereby making tumors susceptible to immune attack. Tue, 31 May 2022 11:18:28 EDT //www.koonmotors.com/releases/2022/05/220531111828.htm //www.koonmotors.com/releases/2022/05/220531091523.htm A type of white blood cell previously known only as a helper in the immune system appears also to be the instigator of the body's defenses against cancerous tumors. The discovery could lead to more effective cancer immunotherapy, a promising treatment which uses the body's own immune system, rather than radiation, to attack cancer cells. In an animal study, researchers found that a population of T cells called CD4-positive helper T cells helped start a chain of antitumor immunity defenses that allow killer cells to better infiltrate melanoma and breast cancer tumors. Tue, 31 May 2022 09:15:23 EDT //www.koonmotors.com/releases/2022/05/220531091523.htm //www.koonmotors.com/releases/2022/05/220509132630.htm Immunotherapy unleashes the power of the immune system to fight cancer. However, for some patients, immunotherapy doesn't work, and new research may help explain why. When immune cells called T lymphocytes infiltrate malignant tumors, the genetic program of those T cells and the developmental path they then follow, may affect their response to immunotherapy and predict overall patient survival, according to a new study. The results overturn the prevailing model of immune responses in melanoma and present different therapeutic approaches. Mon, 09 May 2022 13:26:30 EDT //www.koonmotors.com/releases/2022/05/220509132630.htm //www.koonmotors.com/releases/2022/04/220414125132.htm Melanoma is a somewhat unusual cancer -- one that blooms before our very eyes, often on sun-exposed skin, and can quickly become deadly as it turns our own skin against us and spreads to other organs. Fortunately, when caught early, melanoma can often be cured by simple surgery, and there are now better treatments for advanced cases, including immunotherapies that prime a patient's immune system to fight off the cancer. However, much remains unknown about melanoma, including the details of how it develops in the earliest stages, and how to best identify and treat the most dangerous early cases. Spatial maps of melanoma reveal how individual cells interact as cancer progresses. Thu, 14 Apr 2022 12:51:32 EDT //www.koonmotors.com/releases/2022/04/220414125132.htm //www.koonmotors.com/releases/2022/04/220406160555.htm Mutation of a gene called ARID2 plays a role in increasing the chance that melanoma, a deadly skin cancer, will turn dangerously metastatic, researchers report. Wed, 06 Apr 2022 16:05:55 EDT //www.koonmotors.com/releases/2022/04/220406160555.htm //www.koonmotors.com/releases/2022/03/220330121402.htm Scientists are using zebrafish to understand human skin cancer that attacks the hands and feet. Wed, 30 Mar 2022 12:14:02 EDT //www.koonmotors.com/releases/2022/03/220330121402.htm //www.koonmotors.com/releases/2022/03/220323130313.htm The U.S. Food and Drug Administration has approved a novel therapy for patients with metastatic or inoperable melanoma, an aggressive type of skin cancer. 结婚,2022年3月23日13:03:13美国东部时间 //www.koonmotors.com/releases/2022/03/220323130313.htm //www.koonmotors.com/releases/2022/03/220311115316.htm Researchers reveal key differences in the cellular and molecular composition of acral melanoma compared to melanoma. Their findings may lead to new potential therapeutic targets for this rare disease. Fri, 11 Mar 2022 11:53:16 EST //www.koonmotors.com/releases/2022/03/220311115316.htm //www.koonmotors.com/releases/2022/03/220309090654.htm Amyloid beta, a protein known to build-up in the brains of Alzheimer's patients, also helps skin cancer cells thrive when they spread to the brain, a new study finds. Wed, 09 Mar 2022 09:06:54 EST //www.koonmotors.com/releases/2022/03/220309090654.htm //www.koonmotors.com/releases/2022/03/220304124017.htm For years, surgery for patients with stage III melanoma -- melanoma that has spread to the lymph nodes -- involved removing those lymph nodes along with the primary tumor. Known as completion lymph node dissection (CLND), the surgery was meant to ensure that no cancer remained after surgery. More recently, however, cancer surgeons have discovered that CLND has the potential to cause more problems than it solves. In most cases, patients do better on immunotherapy alone than they do when their surgery involves removal of the lymph nodes, due to potential complications from lymph node surgery. Fri, 04 Mar 2022 12:40:17 EST //www.koonmotors.com/releases/2022/03/220304124017.htm //www.koonmotors.com/releases/2022/02/220228114419.htm 迄今为止最大的研究证实b的链接etween the gut microbiome and the response to cancer immunotherapy therapy for melanoma. Mon, 28 Feb 2022 11:44:19 EST //www.koonmotors.com/releases/2022/02/220228114419.htm //www.koonmotors.com/releases/2022/02/220228114333.htm Melanoma patients receiving therapy that helps their immune system kill cancer cells respond to treatment differently depending on the types of microbes in their gut, and new research suggests the microorganisms hindering therapy have more influence than the beneficial ones. Mon, 28 Feb 2022 11:43:33 EST //www.koonmotors.com/releases/2022/02/220228114333.htm //www.koonmotors.com/releases/2022/02/220223111226.htm Patients treated for Merkel cell carcinoma (MCC) face a five-year recurrence rate of 40% -- markedly higher than the recurrence rates for melanoma and other skin cancers. Additionally, in the study cohort of more than 600 patients, 95% of MCC recurrences happened in the first three years, suggesting that surveillance efforts should be focused on that span. Wed, 23 Feb 2022 11:12:26 EST //www.koonmotors.com/releases/2022/02/220223111226.htm //www.koonmotors.com/releases/2022/02/220217102023.htm A team of researchers has discovered blood biomarkers that can potentially predict patient response in the treatment of melanoma. Thu, 17 Feb 2022 10:20:23 EST //www.koonmotors.com/releases/2022/02/220217102023.htm //www.koonmotors.com/releases/2022/02/220202111801.htm Castalagin, a polyphenol from the Amazonian fruit camu-camu, increases the efficacy of immunotherapy in mice by modifying their microbiome, researchers find. Wed, 02 Feb 2022 11:18:01 EST //www.koonmotors.com/releases/2022/02/220202111801.htm //www.koonmotors.com/releases/2022/01/220118123623.htm A new data portal called Cancer-Immu established by a team of biostatisticians can help cancer clinicians and researchers predict which patients will respond to immune checkpoint inhibitors. With data from 3,652 samples for 16 cancer types, Cancer-Immu is the largest immune checkpoint blockade-related data portal for exploring immunogenomic connections. Tue, 18 Jan 2022 12:36:23 EST //www.koonmotors.com/releases/2022/01/220118123623.htm //www.koonmotors.com/releases/2022/01/220112093811.htm Research suggests that a vaccine stimulating production of a protein critical to the skin's antioxidant network could help people bolster their defenses against skin cancer. Wed, 12 Jan 2022 09:38:11 EST //www.koonmotors.com/releases/2022/01/220112093811.htm //www.koonmotors.com/releases/2022/01/220111111949.htm A new study reveals important insights into the molecular mechanisms that underpin the body's natural defences against the development of skin cancer. The protein CSDE1 coordinates a complex chain of events that enable senescence in skin cells. The senescent cells act as a firewall against cancer, suppressing the formation of tumours. The findings are surprising because CSDE1 has been previously linked to driving the formation of cancers. The results offer new clues into the behavior of skin cancer at the cellular level, paving the way for potential new therapeutic targets to treat the disease. Tue, 11 Jan 2022 11:19:49 EST //www.koonmotors.com/releases/2022/01/220111111949.htm //www.koonmotors.com/releases/2021/12/211223143050.htm Melanoma patients receiving therapy that makes it easier for their immune system to kill cancer cells respond to treatment better when their diet is rich in fiber, according to a large, international research collaboration. Thu, 23 Dec 2021 14:30:50 EST //www.koonmotors.com/releases/2021/12/211223143050.htm