//www.koonmotors.com/news/health_medicine/prostate_cancer/ Learn the symptoms of prostate cancer. Read current medical research on new treatment options, vaccines, surgery and prevention. en-us Wed, 06 Sep 2023 14:46:41 EDT Wed, 06 Sep 2023 14:46:41 EDT 60 //www.koonmotors.com/images/scidaily-logo-rss.png//www.koonmotors.com/news/health_medicine/prostate_cancer/ For more science news, visit ScienceDaily. //www.koonmotors.com/releases/2023/08/230821232426.htm Using MRI as a screening test alongside PSA density allowed detection of cancers that would have been missed by the blood test alone, according to new research. Mon, 21 Aug 2023 23:24:26 EDT //www.koonmotors.com/releases/2023/08/230821232426.htm //www.koonmotors.com/releases/2023/08/230815151137.htm Researchers demonstrate how mathematical modeling combined with dynamic biomarkers can be used to characterize metastatic disease and identify appropriate therapeutic approaches to improve patient outcomes. Tue, 15 Aug 2023 15:11:37 EDT //www.koonmotors.com/releases/2023/08/230815151137.htm //www.koonmotors.com/releases/2023/08/230814122244.htm A study uncovers a new mechanism to explain why some prostate tumors switch from a common, treatable form to a more rare and aggressive form of prostate cancer. Mon, 14 Aug 2023 12:22:44 EDT //www.koonmotors.com/releases/2023/08/230814122244.htm //www.koonmotors.com/releases/2023/08/230814122018.htm Patients with localized prostate cancer have a good chance of survival, but mortality rates among those with advanced, metastatic forms of the condition remain high. Until now, the precise mechanism behind the spread of the tumor has not been fully explained. But an international research team has succeeded in decoding the underlying cellular signal pathway and has carried out research using a common diabetes medication that could provide a new treatment option. Mon, 14 Aug 2023 12:20:18 EDT //www.koonmotors.com/releases/2023/08/230814122018.htm //www.koonmotors.com/releases/2023/07/230719112707.htm Three new biomarkers for prostate cancer have been identified to help pinpoint potentially aggressive cases of the disease, which kills 300,000 men each year. Wed, 19 Jul 2023 11:27:07 EDT //www.koonmotors.com/releases/2023/07/230719112707.htm //www.koonmotors.com/releases/2023/07/230712124705.htm Prostate cancer is a leading cause of death among American men, and it's resistant to one of the most powerful chemotherapy medications -- cisplatin. Now, researchers have developed the first therapy of its kind that disrupts prostate cancer cells' metabolism and releases cisplatin into the weakened cells, causing them to die. In mouse models, an orally administered version shrunk tumors substantially. Wed, 12 Jul 2023 12:47:05 EDT //www.koonmotors.com/releases/2023/07/230712124705.htm //www.koonmotors.com/releases/2023/04/230410123651.htm A new drug, a monoclonal antibody known as enoblituzumab, is safe in men with aggressive prostate cancer and may induce clinical activity against cancer throughout the body, according to a phase 2 study. If confirmed in additional studies, enoblituzumab could become the first promising antibody-based immunotherapy agent against prostate cancer. 星期一,2023年4月10 12:36:51美国东部时间 //www.koonmotors.com/releases/2023/04/230410123651.htm //www.koonmotors.com/releases/2023/03/230316212552.htm The combination of two oral medications has shown positive results in people with prostate cancer, whose disease has spread to other parts of the body. Compared with XTANDI plus placebo, the investigatory combination of TALZENNA and XTANDI demonstrated a statistically significant and clinically meaningful improvement in radiographic progression-free survival. Thu, 16 Mar 2023 21:25:52 EDT //www.koonmotors.com/releases/2023/03/230316212552.htm //www.koonmotors.com/releases/2023/03/230309101400.htm New research shows that men who stick to a predominantly Mediterranean diet are less likely to be diagnosed with prostate cancer. This diet also improves their chances of recovery if they have PC and are undergoing radiation treatment. Thu, 09 Mar 2023 10:14:00 EST //www.koonmotors.com/releases/2023/03/230309101400.htm //www.koonmotors.com/releases/2023/03/230308112202.htm 硝酸盐摄入超过一个人的adult lifetime through the consumption of tap water and bottled water could be a risk factor for prostate cancer, particularly in the case of aggressive tumors and in younger men. Wed, 08 Mar 2023 11:22:02 EST //www.koonmotors.com/releases/2023/03/230308112202.htm //www.koonmotors.com/releases/2023/02/230207191546.htm Researchers have helped develop a new blood test to detect prostate cancer with greater accuracy than current methods. New research shows that the Prostate Screening EpiSwitch (PSE) blood test is 94 per cent accurate -- beating the currently used prostate-specific antigen (PSA) blood test. The research team say that the new test shows significant potential as an accurate and rapid cancer screening diagnostic. Tue, 07 Feb 2023 19:15:46 EST //www.koonmotors.com/releases/2023/02/230207191546.htm //www.koonmotors.com/releases/2023/01/230123200332.htm Researchers discover a potential therapeutic avenue via neuronal endocrine receptors that could be helpful in battling an aggressive form of prostate cancer. Mon, 23 Jan 2023 20:03:32 EST //www.koonmotors.com/releases/2023/01/230123200332.htm //www.koonmotors.com/releases/2023/01/230112113156.htm For men who undergo radiotherapy for localized prostate cancer, the precise targeting capabilities of MRI guidance resulted in fewer toxicities and better quality of life according to new research. Thu, 12 Jan 2023 11:31:56 EST //www.koonmotors.com/releases/2023/01/230112113156.htm //www.koonmotors.com/releases/2022/12/221214092345.htm A single bout of exercise has been shown to elevate anti-cancer proteins called myokines in people with advanced prostate cancer, to levels which can significantly suppress tumour growth. Wed, 14 Dec 2022 09:23:45 EST //www.koonmotors.com/releases/2022/12/221214092345.htm //www.koonmotors.com/releases/2022/12/221213134414.htm Researchers have characterised prostate cancer cell dynamics at a single-cell resolution across the timespan of the disease -- from its beginning to the point of androgen independence, where the tumour no longer responds to hormone deprivation therapy. Tue, 13 Dec 2022 13:44:14 EST //www.koonmotors.com/releases/2022/12/221213134414.htm //www.koonmotors.com/releases/2022/12/221209175746.htm Scientists have created a comprehensive tool for predicting an individual's risk of developing prostate cancer, which they say could help ensure that those men at greatest risk will receive the appropriate testing while reducing unnecessary -- and potentially invasive -- testing for those at very low risk. Fri, 09 Dec 2022 17:57:46 EST //www.koonmotors.com/releases/2022/12/221209175746.htm //www.koonmotors.com/releases/2022/11/221129165854.htm A family history of cancer and genetic variants that might be inherited appear to be important risk factors for Black men diagnosed with early-onset prostate cancer, a study has found. Tue, 29 Nov 2022 16:58:54 EST //www.koonmotors.com/releases/2022/11/221129165854.htm //www.koonmotors.com/releases/2022/11/221123114207.htm A single drug compound simultaneously attacks hard-to-treat prostate cancer on several fronts, according to a new study in mice and human cells. It triggers immune cells to attack, helps the immune cells penetrate the tumor, and cuts off the tumor's ability to burn testosterone as fuel, according to new research. Wed, 23 Nov 2022 11:42:07 EST //www.koonmotors.com/releases/2022/11/221123114207.htm //www.koonmotors.com/releases/2022/11/221109085809.htm Researchers have found a new theranostic compound that effectively shrinks prostate tumor in mice. Theranostics is a cancer treatment that involves finding cancer cells anywhere in the body and delivering targeted radiation to kill those cells, by drugs that contain radioactive isotopes. It means that this compound could be a promising option for treating hormone-resistant metastases in patients with recurrent cancers. Wed, 09 Nov 2022 08:58:09 EST //www.koonmotors.com/releases/2022/11/221109085809.htm //www.koonmotors.com/releases/2022/11/221102135650.htm In a recent trial, nine patients whose tumors were resistant to androgen-blocking therapy continued that therapy but were also given a CD105 inhibitor called carotuximab. Forty percent of those patients experienced progression-free survival, based on radiographic imaging Wed, 02 Nov 2022 13:56:50 EDT //www.koonmotors.com/releases/2022/11/221102135650.htm //www.koonmotors.com/releases/2022/10/221003110230.htm New epigenetic biomarkers to predict more aggressive forms of prostate cancer have been discovered. Mon, 03 Oct 2022 11:02:30 EDT //www.koonmotors.com/releases/2022/10/221003110230.htm //www.koonmotors.com/releases/2022/09/220922124513.htm Researchers have identified critical genomic changes in response to abiraterone acetate/prednisone, a standard treatment option for men with progressive, incurable and castration-resistant prostate cancer. Thu, 22 Sep 2022 12:45:13 EDT //www.koonmotors.com/releases/2022/09/220922124513.htm //www.koonmotors.com/releases/2022/09/220921210011.htm Researchers have made an important discovery about how prostate cancer may start to develop. A new study reveals that the prostate as a whole, including cells that appear normal, is different in men with prostate cancer. It suggests that tissue cells throughout the whole prostate are primed and ready to develop prostate cancer. This means that it may be better to treat the whole prostate rather than only the areas in the prostate that have cancer. The team hope their work could help scientists better understand the causes of prostate cancer, and even prevent it altogether. Wed, 21 Sep 2022 21:00:11 EDT //www.koonmotors.com/releases/2022/09/220921210011.htm //www.koonmotors.com/releases/2022/09/220915104739.htm A new study suggests androgen receptor inhibitors can fundamentally rewire and reshape how prostate tumors function, and in certain cases even make them more aggressive. Thu, 15 Sep 2022 10:47:39 EDT //www.koonmotors.com/releases/2022/09/220915104739.htm //www.koonmotors.com/releases/2022/09/220912132329.htm The HSD3B1 gene could hold clues for predicting and treating endometrial cancer, according to a novel finding. Researchers found a certain HSD3B1 genotype was more common in women with type 2 endometrial cancer. Those patients show lower survival rates than those diagnosed with type 1 endometrial cancer, likely driven by the fact that type 2 patient cells are less hormone-dependent. Mon, 12 Sep 2022 13:23:29 EDT //www.koonmotors.com/releases/2022/09/220912132329.htm //www.koonmotors.com/releases/2022/08/220831113714.htm Two pioneering studies have identified genetic signatures explaining ethnic differences in the severity of prostate cancer, particularly in sub-Saharan Africa. Wed, 31 Aug 2022 11:37:14 EDT //www.koonmotors.com/releases/2022/08/220831113714.htm //www.koonmotors.com/releases/2022/08/220818091300.htm A large-scale study looked at the impact of incorporating genetic risk for cancer into the GP triage and referral processes in the UK. The research concluded that considering genetic risk could improve referrals for those in need -- and importantly, avoid invasive biopsy investigations for those at low risk of cancer. Assessing genetic risk in primary care could lead to earlier diagnosis for men most at risk of prostate cancer. Thu, 18 Aug 2022 09:13:00 EDT //www.koonmotors.com/releases/2022/08/220818091300.htm //www.koonmotors.com/releases/2022/08/220810123546.htm Researchers have found that individual prostate tumors contain a previously unknown range of genetic variation. Wed, 10 Aug 2022 12:35:46 EDT //www.koonmotors.com/releases/2022/08/220810123546.htm //www.koonmotors.com/releases/2022/08/220803203926.htm Men with early, curable stages of prostate cancer are missing opportunities to have their cancer detected because national guidelines and media health campaigns focus on urinary symptoms despite a lack of scientific evidence, say experts in the UK. Wed, 03 Aug 2022 20:39:26 EDT //www.koonmotors.com/releases/2022/08/220803203926.htm //www.koonmotors.com/releases/2022/07/220720121044.htm Researchers have developed a new blood test that provides unprecedented insight into a patient's cancer make-up, potentially allowing doctors to better select treatment options that will improve patient outcomes. Wed, 20 Jul 2022 12:10:44 EDT //www.koonmotors.com/releases/2022/07/220720121044.htm //www.koonmotors.com/releases/2022/07/220718094504.htm Prostate cancer is a common form of cancer. Researchers have now discovered a faster and easier way to determine who has an aggressive form of cancer, and who has not. Mon, 18 Jul 2022 09:45:04 EDT //www.koonmotors.com/releases/2022/07/220718094504.htm //www.koonmotors.com/releases/2022/06/220615145724.htm Researchers reveal a mechanism by which prostate cancer cells become resistant through molecular modification of the androgen receptor protein and identify a potential treatment approach that could overcome this resistance. Wed, 15 Jun 2022 14:57:24 EDT //www.koonmotors.com/releases/2022/06/220615145724.htm //www.koonmotors.com/releases/2022/06/220615102926.htm High-intensity focused ultrasound (HIFU) can help some men with prostate cancer avoid surgery or radiation. Wed, 15 Jun 2022 10:29:26 EDT //www.koonmotors.com/releases/2022/06/220615102926.htm //www.koonmotors.com/releases/2022/06/220609195008.htm Male sex hormones interfere with the body's ability to fight bladder cancer, likely explaining why males experience higher cancer rates and more deadly disease, according to a new study. Thu, 09 Jun 2022 19:50:08 EDT //www.koonmotors.com/releases/2022/06/220609195008.htm //www.koonmotors.com/releases/2022/05/220527121419.htm Researchers have identified a previously unrecognized form of hormone therapy-resistant prostate cancer, as well as a set of molecules that drive its growth. This discovery opens the door to the development of therapies that treat this specific disease. Fri, 27 May 2022 12:14:19 EDT //www.koonmotors.com/releases/2022/05/220527121419.htm //www.koonmotors.com/releases/2022/05/220526125753.htm Practice-changing research shows that a combination of androgen deprivation therapy -- a commonly used hormone injection -- plus pelvic lymph node radiation, kept nearly 90% of clinical trial patients' prostate cancer at bay for five years. Thu, 26 May 2022 12:57:53 EDT //www.koonmotors.com/releases/2022/05/220526125753.htm //www.koonmotors.com/releases/2022/05/220525151750.htm Men taking either of the two most common oral medications for advanced prostate cancer who had also undergone hormone therapy to treat their disease were at higher risk of serious metabolic or cardiovascular issues than patients who were only receiving hormone therapy, researchers found. Wed, 25 May 2022 15:17:50 EDT //www.koonmotors.com/releases/2022/05/220525151750.htm //www.koonmotors.com/releases/2022/05/220510185445.htm Investigators have discovered that tumor cells use mitochondria to control their growth and detect stress that can destroy a tumor cell if it is not controlled. Tue, 10 May 2022 18:54:45 EDT //www.koonmotors.com/releases/2022/05/220510185445.htm //www.koonmotors.com/releases/2022/04/220422114745.htm Over the past 15 years, public health authorities have downgraded recommendations for the prostate-specific antigen (PSA) test as a screening tool to reduce the overdiagnosis and overtreatment of men with low-grade prostate cancer. Now, researchers have found that while these efforts have been effective, the incidence of higher-grade disease and metastasis at diagnosis have risen. Fri, 22 Apr 2022 11:47:45 EDT //www.koonmotors.com/releases/2022/04/220422114745.htm //www.koonmotors.com/releases/2022/04/220413131202.htm Researchers have found that treating prostate cancer cells with novel cyclin-dependent kinase 19 (CDK19) and homologous cyclin-dependent kinase 8 (CDK8) inhibitors reduces their potential to migrate into and invade surrounding structures. These molecules may be used as single or combination therapy for patients with advanced disease to prevent and treat metastatic spread. Wed, 13 Apr 2022 13:12:02 EDT //www.koonmotors.com/releases/2022/04/220413131202.htm //www.koonmotors.com/releases/2022/04/220406132005.htm A research review into molecular insights of a licorice-derived substance called glycyrrhizin for preventing or treating cancer suggests further research could lead to specific agents for clinical use. Wed, 06 Apr 2022 13:20:05 EDT //www.koonmotors.com/releases/2022/04/220406132005.htm //www.koonmotors.com/releases/2022/04/220404105723.htm 前列腺癌是本地化的多数of cases, giving affected individuals a good chance of survival. However, about 20% of patients develop incurable metastatic prostate cancer, resulting in approximately 5,000 deaths each year in Austria alone. Medical research has not yet adequately explained why metastases occur in some people and not in others. A research team has now discovered specific changes in a protein that drive the growth and spread of prostate cancer. Mon, 04 Apr 2022 10:57:23 EDT //www.koonmotors.com/releases/2022/04/220404105723.htm //www.koonmotors.com/releases/2022/03/220321091914.htm A new form of magnetic resonance imaging (MRI) that makes cancerous tissue glow in medical images could help doctors more accurately detect and track the progression of cancer over time. Mon, 21 Mar 2022 09:19:14 EDT //www.koonmotors.com/releases/2022/03/220321091914.htm //www.koonmotors.com/releases/2022/03/220314120700.htm A new study finds that the incidence rate of metastatic prostate cancer has significantly increased for men 45 and older and coincides with recommendations against routine prostate cancer screenings. Mon, 14 Mar 2022 12:07:00 EDT //www.koonmotors.com/releases/2022/03/220314120700.htm //www.koonmotors.com/releases/2022/03/220307190651.htm Researchers developed an algorithm estimating a person's risk of developing prostate cancer based on age and the levels of two prostate cancer markers, PSA and hK2 (human kalliknein peptidase). They found that, by setting a risk threshold above which men are counted as 'screen positive', the approach would reduce the number of false positives by three quarters compared to a standard PSA test, while catching the same proportion of cancers. Mon, 07 Mar 2022 19:06:51 EST //www.koonmotors.com/releases/2022/03/220307190651.htm //www.koonmotors.com/releases/2022/02/220228184019.htm An ultrasound scan can be used to detect cases of prostate cancer, according to new research. Mon, 28 Feb 2022 18:40:19 EST //www.koonmotors.com/releases/2022/02/220228184019.htm //www.koonmotors.com/releases/2022/02/220218110716.htm Results from an international, randomized, double-blind, placebo-controlled, phase 3 clinical trial indicate that adding the androgen-receptor inhibitor darolutamide to androgen-deprivation therapy and chemotherapy prolongs the survival of men with metastatic, hormone-sensitive prostate cancer. Fri, 18 Feb 2022 11:07:16 EST //www.koonmotors.com/releases/2022/02/220218110716.htm //www.koonmotors.com/releases/2022/02/220215125526.htm Scientists have developed mathematical models that act as patient 'surrogates' for evaluating potential prostate cancer treatments. Tue, 15 Feb 2022 12:55:26 EST //www.koonmotors.com/releases/2022/02/220215125526.htm //www.koonmotors.com/releases/2022/02/220207083429.htm Mice are typically used as models in advanced prostate cancer research, but the profound differences between them and humans has long bedeviled the translation of findings from the animal to success in people. Dogs however are the only other animal that suffers from a significant incidence of prostate cancer, and researchers are finding them much more enlightening subjects in identification of drugs that show promise for human patients. Mon, 07 Feb 2022 08:34:29 EST //www.koonmotors.com/releases/2022/02/220207083429.htm //www.koonmotors.com/releases/2022/01/220128100728.htm The combination of a novel blood test and magnetic resonance imaging (MRI) can reduce overdiagnosis of low-risk cancers as well as societal costs in prostate cancer screening, according to a cost-effectiveness study. Fri, 28 Jan 2022 10:07:28 EST //www.koonmotors.com/releases/2022/01/220128100728.htm //www.koonmotors.com/releases/2022/01/220127141613.htm A new analysis has uncovered a potential link between higher prostate cancer risk and genetic variants associated with higher bloodstream levels of the cholesterol-transporting molecule lipoprotein A. Thu, 27 Jan 2022 14:16:13 EST //www.koonmotors.com/releases/2022/01/220127141613.htm //www.koonmotors.com/releases/2022/01/220125162420.htm Faulty versions of the BRCA1 and BRCA2 genes are well known to increase the risk of breast cancer in men and women, and in ovarian cancer. Now BRCA1 and BRCA2 have been linked to several other cancers, including those that affect men. Tue, 25 Jan 2022 16:24:20 EST //www.koonmotors.com/releases/2022/01/220125162420.htm //www.koonmotors.com/releases/2022/01/220113111518.htm Researchers have completed a comprehensive international validation of artificial intelligence (AI) for diagnosing and grading prostate cancer. The study shows that AI systems can identify and grade prostate cancer in tissue samples from different countries equally well as pathologists. The results suggest AI systems are ready to be responsibly introduced as a complementary tool in prostate cancer care, researchers say. Thu, 13 Jan 2022 11:15:18 EST //www.koonmotors.com/releases/2022/01/220113111518.htm //www.koonmotors.com/releases/2022/01/220112121551.htm 在前列腺癌的分子特性ogenous retroviral (ERV) RNA, has been found to have prognostic value and also distinguish differences between men of African and European or Middle Eastern ancestry, according to a new study. The team also identified ERV expression signatures that may be useful for identifying prostate cancer patients at greatest risk of progression regardless of ancestry, which may also extend to progression in other cancers. Wed, 12 Jan 2022 12:15:51 EST //www.koonmotors.com/releases/2022/01/220112121551.htm //www.koonmotors.com/releases/2022/01/220105202807.htm A highly portable and rapid prostate cancer screening kit could provide early warning to populations with higher incidence of prostate cancer and particularly those with limited access to health care, such as African American men. Wed, 05 Jan 2022 20:28:07 EST //www.koonmotors.com/releases/2022/01/220105202807.htm //www.koonmotors.com/releases/2021/11/211129105542.htm Prostate cancer screening results differ in men taking cholesterol-lowering statin drugs compared with non-users, a study finds. In statin users, screening did not increase the incidence of prostate cancer as it did in other men. Mon, 29 Nov 2021 10:55:42 EST //www.koonmotors.com/releases/2021/11/211129105542.htm //www.koonmotors.com/releases/2021/11/211116111315.htm Researchers have pioneered a new method to track the progression of prostate cancer in mice, from its birth to its spread into other tissues. This approach allows researchers to study the origins of prostate cancer in a more realistic context than traditional methods allow. Tue, 16 Nov 2021 11:13:15 EST //www.koonmotors.com/releases/2021/11/211116111315.htm //www.koonmotors.com/releases/2021/11/211105134626.htm 一项新的研究发现一个苏的RNA分子ppresses prostate tumors. The scientists found that prostate cancers develop ways to shut down this RNA molecule to allow themselves to grow. According to the new research -- conducted in mice implanted with human prostate tumor samples -- restoring this so-called long noncoding RNA could be a new strategy to treat prostate cancer that has developed resistance to hormonal therapies. Fri, 05 Nov 2021 13:46:26 EDT //www.koonmotors.com/releases/2021/11/211105134626.htm //www.koonmotors.com/releases/2021/11/211102210147.htm Researchers have shown that a prostate cancer urine test can identify men at 'intermediate risk' who can safely avoid immediate treatment and benefit from 'active surveillance' instead. Previously, the team's Prostate Urine Risk (PUR) test could identify men with high and low risk cancers. But thanks to some fine-tuning, it can now help men with intermediate-risk disease - for whom treatment options had been less clear. Tue, 02 Nov 2021 21:01:47 EDT //www.koonmotors.com/releases/2021/11/211102210147.htm //www.koonmotors.com/releases/2021/10/211028120417.htm Researchers have shown for the first time that diet-associated molecules in the gut are associated with aggressive prostate cancer, suggesting dietary interventions may help reduce risk. While more research will be necessary, the study's lead author says findings from the team's analysis of nearly 700 patients may have clinical implications for diagnosing and preventing lethal prostate cancer. Thu, 28 Oct 2021 12:04:17 EDT //www.koonmotors.com/releases/2021/10/211028120417.htm