//www.koonmotors.com/news/health_medicine/pneumonia/ Read the latest research on pneumonia, including how it is contracted, new treatments and more. en-us Mon, 26 Jun 2023 22:45:23 EDT Mon, 26 Jun 2023 22:45:23 EDT 60 //www.koonmotors.com/images/scidaily-logo-rss.png//www.koonmotors.com/news/health_medicine/pneumonia/ For more science news, visit ScienceDaily. //www.koonmotors.com/releases/2023/04/230425111250.htm Typically T cells of the immune system respond to a specific feature (antigen) of a microbe, thereby generating protective immunity. Scientists have discovered an exception to this rule. Namely, a group of divergent bacterial pathogens, including pneumococci, all share a small highly conserved protein sequence, which is both presented and recognized by human T cells in a conserved population-wide manner. Tue, 25 Apr 2023 11:12:50 EDT //www.koonmotors.com/releases/2023/04/230425111250.htm //www.koonmotors.com/releases/2023/04/230417142525.htm 许多致病bacteria like Streptococcus pneumoniae (S. pneumoniae) are encased in a sugar layer called the capsular polysaccharide (CPS). This layer is often essential for infections. In a ground-breaking discovery, features of the CPS that help the bacteria to colonize the human respiratory tract were identified. The research showed that the structures of the CPS capsule and its types of linkages and combinations matter greatly in allowing the bacteria to better attach and survive on the lining of the upper and lower human respiratory tracts. Mon, 17 Apr 2023 14:25:25 EDT //www.koonmotors.com/releases/2023/04/230417142525.htm //www.koonmotors.com/releases/2023/03/230316140934.htm Pneumococcal disease leads to over three million hospitalizations and hundreds of thousands of deaths annually. A new study suggests that the FDA-approved drug Fomepizole may reduce disease severity in the lungs of mice with some forms of bacterial pneumonia and enhance the efficacy of the antibiotic erythromycin as well. Thu, 16 Mar 2023 14:09:34 EDT //www.koonmotors.com/releases/2023/03/230316140934.htm //www.koonmotors.com/releases/2023/02/230208125111.htm A new study reveals how resistance to bacteraemic pneumonia is provided by a unique subset of lung T regulatory cells. Wed, 08 Feb 2023 12:51:11 EST //www.koonmotors.com/releases/2023/02/230208125111.htm //www.koonmotors.com/releases/2022/09/220922124405.htm Engineers have developed microscopic robots, called microrobots, that can swim around in the lungs, deliver medication and be used to clear up life-threatening cases of bacterial pneumonia. In mice, the microrobots safely eliminated pneumonia-causing bacteria in the lungs and resulted in 100% survival. By contrast, untreated mice all died within three days after infection. Thu, 22 Sep 2022 12:44:05 EDT //www.koonmotors.com/releases/2022/09/220922124405.htm //www.koonmotors.com/releases/2022/08/220817104046.htm A pioneering genomic surveillance study has provided the clearest picture yet of the arms race between Streptococcus pneumoniae, the bacterium responsible for a range of illnesses such as pneumonia and meningitis, and the vaccines designed to protect against the most dominant types. A strain called GPSC10 was found to be a particular threat, due to its increased virulence, ability to transform its structure to evade vaccines and its resistance to several common antibiotics. Wed, 17 Aug 2022 10:40:46 EDT //www.koonmotors.com/releases/2022/08/220817104046.htm //www.koonmotors.com/releases/2022/06/220613150645.htm Many different types of bacteria and viruses can cause pneumonia, but there is no easy way to determine which microbe is causing a particular patient's illness. This uncertainty makes it harder for doctors to choose effective treatments because the antibiotics commonly used to treat bacterial pneumonia won't help patients with viral pneumonia. In addition, limiting the use of antibiotics is an important step toward curbing antibiotic resistance. Mon, 13 Jun 2022 15:06:45 EDT //www.koonmotors.com/releases/2022/06/220613150645.htm //www.koonmotors.com/releases/2022/04/220419124125.htm A new study shows patients hospitalized with COVID-19 pneumonia have a higher risk of developing dementia than those with other types of pneumonia. Tue, 19 Apr 2022 12:41:25 EDT //www.koonmotors.com/releases/2022/04/220419124125.htm //www.koonmotors.com/releases/2022/03/220309104421.htm A real-time electronic decision support system helped clinicians at community hospitals provide best practice care for emergency department patients with pneumonia, resulting in decreased intensive care unit admission, more appropriate antibiotic use, and 38 percent lower overall mortality, according to a new study. Wed, 09 Mar 2022 10:44:21 EST //www.koonmotors.com/releases/2022/03/220309104421.htm //www.koonmotors.com/releases/2021/11/211115123520.htm Researchers have discovered a therapy that targets host cells rather than bacterial cells in treating bacterial pneumonia in rodents. The method involves white blood cells of the immune system called macrophages that eat bacteria, and a group of compounds that are naturally produced in mice and humans called epoxyeicosatrienoic acids or EETs. Mon, 15 Nov 2021 12:35:20 EST //www.koonmotors.com/releases/2021/11/211115123520.htm //www.koonmotors.com/releases/2021/10/211030221802.htm A new study demonstrates that children who are exposed to a certain type of environmental air pollution are more likely to contract community acquired pneumonia, or CAP, and to be hospitalized for longer periods of time. Social factors, including race and socioeconomic status, were also found to be associated with living in high-risk areas for CAP. Sat, 30 Oct 2021 22:18:02 EDT //www.koonmotors.com/releases/2021/10/211030221802.htm //www.koonmotors.com/releases/2021/10/211029103143.htm Researchers report that a recently discovered inflammatory mediator, interleukin-26, appears to have an important role in pneumonia and contribute to the killing of bacteria. Fri, 29 Oct 2021 10:31:43 EDT //www.koonmotors.com/releases/2021/10/211029103143.htm //www.koonmotors.com/releases/2021/07/210715090644.htm 肺炎是孩子们死亡的主要原因n worldwide. A new study identifies an unusual pattern of deadly bacteria with resistance to all standard antibiotic therapy in children with pneumonia in Bangladesh. The findings signal an emerging pandemic of fatal antibiotic resistance. Thu, 15 Jul 2021 09:06:44 EDT //www.koonmotors.com/releases/2021/07/210715090644.htm //www.koonmotors.com/releases/2021/06/210624114336.htm Researchers have found a further reason for the severity of dual infection by influenza and Streptococcus pneumonia -- a new virulence mechanism for a surface protein on the pneumonia-causing bacteria S. pneumoniae. This insight comes 30 years after discovery of that surface protein, called pneumococcal surface protein A. This mechanism had been missed in the past because it facilitates bacterial adherence only to dying lung epithelial cells, not to living cells. Thu, 24 Jun 2021 11:43:36 EDT //www.koonmotors.com/releases/2021/06/210624114336.htm //www.koonmotors.com/releases/2021/05/210511160723.htm In a new study, researchers have found a possible link between poor sense of smell and a higher risk of pneumonia hospitalization. Tue, 11 May 2021 16:07:23 EDT //www.koonmotors.com/releases/2021/05/210511160723.htm //www.koonmotors.com/releases/2021/05/210506105342.htm A new study has shown that most patients discharged from hospital after experiencing severe COVID-19 infection appear to return to full health, although up to a third do still have evidence of effects upon the lungs one year on. Thu, 06 May 2021 10:53:42 EDT //www.koonmotors.com/releases/2021/05/210506105342.htm //www.koonmotors.com/releases/2021/03/210308111907.htm The study, involving 281 Ontario children, found that 85.7% of those who received the short course of antibiotics and 84.1% of those who received the longer course of medication were cured two to three weeks later. Mon, 08 Mar 2021 11:19:07 EST //www.koonmotors.com/releases/2021/03/210308111907.htm //www.koonmotors.com/releases/2021/02/210224090655.htm A rise in vaccine-resistant bacteria shows the need for a new vaccine to fight childhood empyema after a spike in hospitalisations, a new study reveals. Wed, 24 Feb 2021 09:06:55 EST //www.koonmotors.com/releases/2021/02/210224090655.htm //www.koonmotors.com/releases/2021/01/210121150944.htm Researchers have identified genetic factors that increase the risk for developing pneumonia and its severe, life-threatening consequences. Thu, 21 Jan 2021 15:09:44 EST //www.koonmotors.com/releases/2021/01/210121150944.htm //www.koonmotors.com/releases/2021/01/210115091340.htm Researchers have developed a DNA test to quickly identify secondary infections in COVID-19 patients, who have double the risk of developing pneumonia while on ventilation than non-COVID-19 patients. Fri, 15 Jan 2021 09:13:40 EST //www.koonmotors.com/releases/2021/01/210115091340.htm //www.koonmotors.com/releases/2020/12/201216134644.htm The bacteria Streptococcus pneumoniae colonizes the nasopharynx and can cause pneumonia. Then, it can spread to the bloodstream and cause organ damage. To understand how this pathogen adapts to different locations in the body, and also how the host responds to the microbe, researchers have measured bacterial and host gene expression at five different sites in a mouse model -- the nasopharynx, lungs, blood, heart and kidneys -- using three genetically different strains of S. pneumoniae. Wed, 16 Dec 2020 13:46:44 EST //www.koonmotors.com/releases/2020/12/201216134644.htm //www.koonmotors.com/releases/2020/12/201208111447.htm New insight on how bacteria in the lungs protect against invading pathogens has been published. Tue, 08 Dec 2020 11:14:47 EST //www.koonmotors.com/releases/2020/12/201208111447.htm //www.koonmotors.com/releases/2020/11/201125122333.htm It is largely unknown why influenza infections lead to an increased risk of bacterial pneumonia. Researchers have now described important findings leading to so-called superinfections, which claim many lives around the world every year. Wed, 25 Nov 2020 12:23:33 EST //www.koonmotors.com/releases/2020/11/201125122333.htm //www.koonmotors.com/releases/2020/11/201120095908.htm Researchers performed a genetic analysis of T cells from lung tissue of COVID-19 patients. They found abnormalities that resulted in T cell overreaction that may cause severe pneumonia. Fri, 20 Nov 2020 09:59:08 EST //www.koonmotors.com/releases/2020/11/201120095908.htm //www.koonmotors.com/releases/2020/10/201028110631.htm A team of infectious disease researchers has developed a new method to identify virulence genes in Streptococcus pneumoniae, the leading cause of bacterial pneumonia. Using this technique in a mouse model of pneumonia, they were able to gain new insights into the progression of the disease and its interaction with the flu virus. Wed, 28 Oct 2020 11:06:31 EDT //www.koonmotors.com/releases/2020/10/201028110631.htm //www.koonmotors.com/releases/2020/09/200910100620.htm A pneumococcal vaccine was effective at protecting children in Laos against the most severe type of pneumonia, a new study has found. Thu, 10 Sep 2020 10:06:20 EDT //www.koonmotors.com/releases/2020/09/200910100620.htm //www.koonmotors.com/releases/2020/08/200828081032.htm Influenza and pneumonia vaccinations are associated with fewer hospital deaths in patients with heart failure. That's the result of a study in nearly 3 million Americans. One out of five individuals will develop heart failure in their lifetime. An estimated 26 million people are affected worldwide. Fri, 28 Aug 2020 08:10:32 EDT //www.koonmotors.com/releases/2020/08/200828081032.htm //www.koonmotors.com/releases/2020/07/200727114726.htm Flu (influenza) and pneumonia vaccinations are associated with reduced risk of Alzheimer's disease, according to new research. Mon, 27 Jul 2020 11:47:26 EDT //www.koonmotors.com/releases/2020/07/200727114726.htm //www.koonmotors.com/releases/2020/07/200709172828.htm A new article investigating the differences in CT findings between coronavirus disease (COVID-19) pneumonia and influenza virus pneumonia found that most lesions from COVID-19 were located in the peripheral zone and close to the pleura, whereas influenza virus was more prone to show mucoid impaction and pleural effusion. The more important role of CT during the present pandemic is in finding lesions and evaluating the effects of treatment. Thu, 09 Jul 2020 17:28:28 EDT //www.koonmotors.com/releases/2020/07/200709172828.htm //www.koonmotors.com/releases/2020/06/200603100438.htm A recent study found that nitrogen-containing bisphosphonates (N-BPs) such as alendronate, which are widely used to treat postmenopausal osteoporosis, are linked with lower risks of pneumonia and of dying from pneumonia. Wed, 03 Jun 2020 10:04:38 EDT //www.koonmotors.com/releases/2020/06/200603100438.htm //www.koonmotors.com/releases/2020/04/200429133955.htm Childhood vaccination may be a powerful tool in the fight against antimicrobial resistance in low- and middle-income countries, finds a new analysis. The study found that immunization with two common vaccines -- the pneumococcal conjugate and rotavirus vaccines -- significantly reduces the rates of acute respiratory infections and diarrhea among small children in these settings. And, with fewer children getting sick or severely sick, fewer are receiving antibiotic treatment. Wed, 29 Apr 2020 13:39:55 EDT //www.koonmotors.com/releases/2020/04/200429133955.htm //www.koonmotors.com/releases/2020/04/200401150833.htm Updated CT scoring criteria that considers lobe involvement, as well as changes in CT findings (i.e., ground-glass opacity, crazy-paving pattern, and consolidation), could quantitatively and accurately evaluate the progression of coronavirus disease (COVID-19) pneumonia, according to a new article. Wed, 01 Apr 2020 15:08:33 EDT //www.koonmotors.com/releases/2020/04/200401150833.htm //www.koonmotors.com/releases/2020/03/200324202028.htm Infections are still responsible for one in five childhood deaths in England and Wales, with respiratory infections topping the league table of known causes, reveals an analysis of the most up to date figures. Tue, 24 Mar 2020 20:20:28 EDT //www.koonmotors.com/releases/2020/03/200324202028.htm //www.koonmotors.com/releases/2020/03/200303175318.htm New research on the novel coronavirus (COVID-19) is a multi-center study (n=101) of the relationship between chest CT findings and the clinical conditions of COVID-19 pneumonia -- which determined that most patients with the disease have ground-glass opacities (GGO) (86.1%) or mixed GGO and consolidation (64.4%) and vascular enlargement in the lesion (71.3%). CT involvement score can help evaluate the severity and extent of COVID-19 pneumonia. Tue, 03 Mar 2020 17:53:18 EST //www.koonmotors.com/releases/2020/03/200303175318.htm //www.koonmotors.com/releases/2020/02/200226130512.htm Doctors who use drugs that target antibiotic-resistant bacteria as a first-line defense against pneumonia should probably reconsider this approach, according to a new study of more than 88,000 veterans hospitalized with the disease. The study found that pneumonia patients given these medications in the first days after hospitalization fared no better than those receiving standard medical care for the condition. Wed, 26 Feb 2020 13:05:12 EST //www.koonmotors.com/releases/2020/02/200226130512.htm //www.koonmotors.com/releases/2020/01/200128122723.htm Researchers have determined that after lungs recover from infection, alveolar macrophages (immune cells that live in the lungs and help protect the lungs against infection) are different in multiple ways and those differences persist indefinitely. Tue, 28 Jan 2020 12:27:23 EST //www.koonmotors.com/releases/2020/01/200128122723.htm //www.koonmotors.com/releases/2020/01/200123080716.htm A new study shows that exposure to diesel exhaust particles (DEPs) can increase an individual's susceptibility to pneumococcal disease. Thu, 23 Jan 2020 08:07:16 EST //www.koonmotors.com/releases/2020/01/200123080716.htm //www.koonmotors.com/releases/2020/01/200106123428.htm This is the first time a clock gene has been found to affect resistance to bacterial pneumonia, a fatal disease responsible for 5% of all deaths in the UK each year. Mon, 06 Jan 2020 12:34:28 EST //www.koonmotors.com/releases/2020/01/200106123428.htm //www.koonmotors.com/releases/2019/11/191112095743.htm A new study has found severe pneumonia decreases by 35 per cent in children who receive a vaccine against a pneumonia-causing bacteria. 星期二,2019年11月12日09:57:43 EST //www.koonmotors.com/releases/2019/11/191112095743.htm //www.koonmotors.com/releases/2019/11/191101100144.htm Low blood oxygen is more common in sick children than previously thought, and strongly increases children's risk of death, Australian-led research has found. Fri, 01 Nov 2019 10:01:44 EDT //www.koonmotors.com/releases/2019/11/191101100144.htm //www.koonmotors.com/releases/2019/10/191001182235.htm Researchers have now identified specific fragments of genetic material that play a role in the development of respiratory failure and sepsis in pneumonia patients. The findings could enable doctors to test quickly for these biological markers when a patient is admitted to hospital with pneumonia, so that they could anticipate complications and provide more intensive support and monitoring. Tue, 01 Oct 2019 18:22:35 EDT //www.koonmotors.com/releases/2019/10/191001182235.htm //www.koonmotors.com/releases/2019/09/190930104505.htm From 20 minutes or more to 10 seconds. Researchers from Intermountain Healthcare and Stanford University say 10 seconds is about how quickly a new system they studied that utilizes artificial intelligence took to accurately identify key findings in chest X-rays of patients in the emergency department suspected of having pneumonia. Mon, 30 Sep 2019 10:45:05 EDT //www.koonmotors.com/releases/2019/09/190930104505.htm //www.koonmotors.com/releases/2019/09/190925101201.htm Researchers have identified two key proteins, ASC and NLRP3, in the maintenance of the innate immune homeostasis in the airway. These proteins do so by a caspase-1-independent mechanism, suggesting that there may be multiple mechanisms involved in protection against microbial infections. Wed, 25 Sep 2019 10:12:01 EDT //www.koonmotors.com/releases/2019/09/190925101201.htm //www.koonmotors.com/releases/2019/09/190919142336.htm Non-alcoholic fatty liver disease (NAFLD) is the build-up of fat in the liver due to factors other than alcohol, but its cause remains unknown. Now, researchers have linked NAFLD to gut bacteria that produce a large amount of alcohol in the body, finding these bacteria in over 60% of NAFLD patients. Their findings could help develop a screening method for early diagnosis and treatment of non-alcoholic fatty liver. Thu, 19 Sep 2019 14:23:36 EDT //www.koonmotors.com/releases/2019/09/190919142336.htm //www.koonmotors.com/releases/2019/09/190906133958.htm Investigators have identified a previously unrecognized characteristic of the vaping-related respiratory illness that has been emerging in clusters across the US in recent months. Within these patients' lungs are large immune cells containing numerous oily droplets, called lipid-laden macrophages. The finding may allow doctors to definitively diagnose the nascent syndrome more quickly and could provide clues into causes of the condition. Fri, 06 Sep 2019 13:39:58 EDT //www.koonmotors.com/releases/2019/09/190906133958.htm //www.koonmotors.com/releases/2019/08/190822141921.htm Researchers have uncovered a crucial link between dietary zinc intake and protection against Streptococcus pneumoniae, the primary bacterial cause of pneumonia. Thu, 22 Aug 2019 14:19:21 EDT //www.koonmotors.com/releases/2019/08/190822141921.htm //www.koonmotors.com/releases/2019/07/190708172434.htm 一年一百万次,肺炎发送美国dults to the hospital. And while antibiotics help save lives, a new study shows two-thirds receive more antibiotics than they probably need. It's not the care that happens in the hospital that leads to over-treatment, the study finds. Rather, it's the prescriptions that patients receive as they head home from the hospital. In all, 93% of the overly long antibiotic prescriptions given to pneumonia patients were written at hospital discharge. Mon, 08 Jul 2019 17:24:34 EDT //www.koonmotors.com/releases/2019/07/190708172434.htm //www.koonmotors.com/releases/2019/06/190610142019.htm Researchers have mapped the most common bacterial cause of pneumonia around the world and revealed how these bacteria evolve in response to vaccination. Scientists from the Wellcome Sanger Institute and their collaborators carried out a global genomic survey of Streptococcus pneumoniae, discovering 621 strains across more than fifty countries. Published in The Lancet Infectious Diseases, the study will help predict which strains will be important for new pneumococcal vaccines. Mon, 10 Jun 2019 14:20:19 EDT //www.koonmotors.com/releases/2019/06/190610142019.htm //www.koonmotors.com/releases/2019/06/190604131207.htm Preschool children with community-acquired pneumonia often receive unnecessary tests and treatment at outpatient clinics and emergency departments, according to a nationally representative study. Tue, 04 Jun 2019 13:12:07 EDT //www.koonmotors.com/releases/2019/06/190604131207.htm //www.koonmotors.com/releases/2019/04/190416131522.htm A vaccine against Streptococcus pneumoniae, a major cause of childhood illness and mortality in the developing world, sharply reduced the incidence of serious pneumococcal disease among children in a large Kenyan community after it was introduced in 2011, according to a new study. Tue, 16 Apr 2019 13:15:22 EDT //www.koonmotors.com/releases/2019/04/190416131522.htm //www.koonmotors.com/releases/2019/03/190311101215.htm Researchers have applied molecular evolutionary analysis to quantify the severity of negative selection pressures on genes encoding the pneumococcal choline-binding proteins (CBPs). They found particularly strong selective constraints on the gene cbpJ, suggesting its importance for bacterial infection. Further analyses revealed its role in bacterial evasion of host neutrophils, suggesting CbpJ's value as a target for drugs against streptococci. Mon, 11 Mar 2019 10:12:15 EDT //www.koonmotors.com/releases/2019/03/190311101215.htm //www.koonmotors.com/releases/2019/03/190304100002.htm If mitigating racial disparities in those who contract pneumococcal diseases, such as meningitis and pneumonia, is a top public health priority, then recommending that all adults get a pneumococcal vaccine at age 50 would likely be effective guidance. Mon, 04 Mar 2019 10:00:02 EST //www.koonmotors.com/releases/2019/03/190304100002.htm //www.koonmotors.com/releases/2019/01/190107110829.htm Taking prescribed opioids raises the risk of pneumonia in individuals with and without HIV, a new study finds. Mon, 07 Jan 2019 11:08:29 EST //www.koonmotors.com/releases/2019/01/190107110829.htm //www.koonmotors.com/releases/2018/11/181112131644.htm Pneumococci are the most common cause of respiratory tract infections, such as otitis and sinusitis, as well as of severe infections like pneumonia and meningitis. A new study shows how the bacteria can inhibit immune cell reaction and survive inside cells to give rise to pneumonia. Mon, 12 Nov 2018 13:16:44 EST //www.koonmotors.com/releases/2018/11/181112131644.htm //www.koonmotors.com/releases/2018/11/181112082436.htm Heart complications in patients diagnosed with bacterial pneumonia are more serious than in patients diagnosed with viral pneumonia, according to new research. Mon, 12 Nov 2018 08:24:36 EST //www.koonmotors.com/releases/2018/11/181112082436.htm //www.koonmotors.com/releases/2018/11/181108142156.htm A new report finds health systems are falling woefully short of ensuring the most vulnerable children have sufficient access to prevention and treatment services in 15 countries that account for 70% of the global pneumonia and diarrhea deaths in children under five. Thu, 08 Nov 2018 14:21:56 EST //www.koonmotors.com/releases/2018/11/181108142156.htm //www.koonmotors.com/releases/2018/10/181011143125.htm Researchers have identified a molecule that plays a key role in bacterial communication and infection. Their findings add a new word to pneumococcus' molecular dictionary and may lead to novel ways to manipulate the bacteria and prevent infection. Thu, 11 Oct 2018 14:31:25 EDT //www.koonmotors.com/releases/2018/10/181011143125.htm //www.koonmotors.com/releases/2018/10/181011103625.htm Pneumonia-causing bacteria can be spread through picking and rubbing the nose, according to new research. This study is the first to show that transmission can occur via contact between the nose and the hands after exposure to pneumococcus bacteria. Thu, 11 Oct 2018 10:36:25 EDT //www.koonmotors.com/releases/2018/10/181011103625.htm //www.koonmotors.com/releases/2018/07/180705100424.htm Besides the patient's condition, pneumococcal DNA also appears to provide information about the course of an infection. Researchers describe several pneumococcal genes predicting whether a patient runs the risk of developing meningitis or dying from the disease. Use of such genetic tests can improve infection diagnostics. Thu, 05 Jul 2018 10:04:24 EDT //www.koonmotors.com/releases/2018/07/180705100424.htm //www.koonmotors.com/releases/2018/06/180611225015.htm 儿童死亡的两个主要细菌引起of pneumonia and meningitis, pneumococcus and Hib, declined sharply during the period 2000 to 2015, especially as vaccines against these pathogens were introduced in high-burden countries, according to new estimates. Mon, 11 Jun 2018 22:50:15 EDT //www.koonmotors.com/releases/2018/06/180611225015.htm