//www.koonmotors.com/news/health_medicine/ovarian_cancer/ Information about ovarian cancer symptoms and treatments. Explore the latest medical research on ovarian cysts and ovarian cancer including including stages of the disease and new treatment options. en-us Wed, 06 Sep 2023 14:45:59 EDT Wed, 06 Sep 2023 14:45:59 EDT 60 //www.koonmotors.com/images/scidaily-logo-rss.png//www.koonmotors.com/news/health_medicine/ovarian_cancer/ For more science news, visit ScienceDaily. //www.koonmotors.com/releases/2023/08/230803141711.htm CAR-T immune therapies could be effective against solid tumors if the right targets are identified, a new study suggests. The researchers successfully deployed CAR-T in a mouse model of ovarian cancer, a type of aggressive, solid-tumor cancer that has eluded such therapies until now. Thu, 03 Aug 2023 14:17:11 EDT //www.koonmotors.com/releases/2023/08/230803141711.htm //www.koonmotors.com/releases/2023/07/230721113238.htm A preclinical study showed that injecting ovarian tissue-derived differentiated induced pluripotent stem cells can restore hormone production and fertility in mice with premature ovarian failure related to genetic diseases and cancer treatment. Fri, 21 Jul 2023 11:32:38 EDT //www.koonmotors.com/releases/2023/07/230721113238.htm //www.koonmotors.com/releases/2023/07/230712124705.htm Prostate cancer is a leading cause of death among American men, and it's resistant to one of the most powerful chemotherapy medications -- cisplatin. Now, researchers have developed the first therapy of its kind that disrupts prostate cancer cells' metabolism and releases cisplatin into the weakened cells, causing them to die. In mouse models, an orally administered version shrunk tumors substantially. Wed, 12 Jul 2023 12:47:05 EDT //www.koonmotors.com/releases/2023/07/230712124705.htm //www.koonmotors.com/releases/2023/07/230707153839.htm A group has discovered previously unidentified ovarian cancer-specific membrane proteins. Their findings suggest a new strategy to diagnose ovarian cancer. Fri, 07 Jul 2023 15:38:39 EDT //www.koonmotors.com/releases/2023/07/230707153839.htm //www.koonmotors.com/releases/2023/06/230623161153.htm Using 3-D models of ovarian cancer tumors, scientists found differences in gene activity based on where a cell is in a tumor, demonstrating how a cell's location and environment in a cancerous tumor can strongly influence which genes are active and the cell's role in the cancer's biology. Fri, 23 Jun 2023 16:11:53 EDT //www.koonmotors.com/releases/2023/06/230623161153.htm //www.koonmotors.com/releases/2023/03/230328145216.htm Researchers develop a 3D cell culture system to test how inhibiting fibroblast activities can help treat lung cancer. To simulate the tumor microenvironment and mimic real tissues, the team co-cultured lung cancer cells and fibroblasts in a 3D matrix. The researchers then tested the anti-cancer drug cisplatin with and without two anti-fibrotic drugs, nintedanib and pirfenidone. They found that combining the anti-fibrotic drug nintedanib with the anti-cancer drug cisplatin increased the efficacy of the latter. Tue, 28 Mar 2023 14:52:16 EDT //www.koonmotors.com/releases/2023/03/230328145216.htm //www.koonmotors.com/releases/2022/12/221201203926.htm About 80% of people with cancer suffer from significant muscle wasting, or loss of muscle tissue, and 30% of these patients die from this condition. New research in mice finds that the severity of muscle wasting is related to the type, size and location of the tumor. Thu, 01 Dec 2022 20:39:26 EST //www.koonmotors.com/releases/2022/12/221201203926.htm //www.koonmotors.com/releases/2022/11/221130114535.htm Researchers found an existing drug may help decrease side effects of cisplatin, a widely used cancer treatment that was discovered in 1965. Wed, 30 Nov 2022 11:45:35 EST //www.koonmotors.com/releases/2022/11/221130114535.htm //www.koonmotors.com/releases/2022/11/221129134412.htm New research yields a novel method to use ultrasound to enhance machine learning's ability to accurately diagnose -- or rule out -- ovarian cancer. Tue, 29 Nov 2022 13:44:12 EST //www.koonmotors.com/releases/2022/11/221129134412.htm //www.koonmotors.com/releases/2022/11/221110205408.htm Researchers have discovered factors that may make breast and ovarian cancers associated with BRCA1/2 gene mutations more likely to recur. Thu, 10 Nov 2022 20:54:08 EST //www.koonmotors.com/releases/2022/11/221110205408.htm //www.koonmotors.com/releases/2022/10/221025112544.htm A new approach to cancer immunotherapy that uses one type of immune cell to kill another -- rather than directly attacking the cancer -- provokes a robust anti-tumor immune response that shrinks ovarian, lung, and pancreatic tumors in preclinical disease models, according to researchers. The study involved a twist on a type of therapy that uses immune cells known as CAR T cells. Tue, 25 Oct 2022 11:25:44 EDT //www.koonmotors.com/releases/2022/10/221025112544.htm //www.koonmotors.com/releases/2022/10/221012103219.htm 观察细胞在粘液ovar组织ian cancer can lead to new treatment options, study shows. Wed, 12 Oct 2022 10:32:19 EDT //www.koonmotors.com/releases/2022/10/221012103219.htm //www.koonmotors.com/releases/2022/09/220913140855.htm Researchers have developed a promising, first-of-its-kind messenger RNA therapy for ovarian cancer as well as cachexia, a muscle-wasting condition associated with cancer and other chronic illnesses. Tue, 13 Sep 2022 14:08:55 EDT //www.koonmotors.com/releases/2022/09/220913140855.htm //www.koonmotors.com/releases/2022/05/220504110424.htm Researchers share the identification of a new potential target for CAR T cells called OR2H1 that they have demonstrated inhibits growth in lung and ovarian tumors. Wed, 04 May 2022 11:04:24 EDT //www.koonmotors.com/releases/2022/05/220504110424.htm //www.koonmotors.com/releases/2022/04/220414125103.htm Researchers want to improve their understanding of the immune environment in ovarian cancer in hopes of making immunotherapy an option for these patients. Researchers now report on key characteristics of immune cells in ovarian cancer and identify cell types important for mediating an immune response. Thu, 14 Apr 2022 12:51:03 EDT //www.koonmotors.com/releases/2022/04/220414125103.htm //www.koonmotors.com/releases/2022/03/220330111401.htm Researchers have found that treatment with miR-634 reduces the resistance of oral squamous cell carcinoma cells to cisplatin, resulting in increased tumor cell killing. An ointment containing miR-634 had a similar effect in mice, suggesting that this simple topical treatment could be used to improve the prognosis of patients with advanced oral cancer. Wed, 30 Mar 2022 11:14:01 EDT //www.koonmotors.com/releases/2022/03/220330111401.htm //www.koonmotors.com/releases/2022/03/220322122822.htm The appearance of ovarian lesions on ultrasound is an effective predictor of cancer risk that can help women avoid unnecessary surgery, according to a new study. Tue, 22 Mar 2022 12:28:22 EDT //www.koonmotors.com/releases/2022/03/220322122822.htm //www.koonmotors.com/releases/2022/03/220316145827.htm A research team has discovered novel metabolic mechanisms that contribute to how ovarian cancer escapes from immune attack, and how combination therapies can exploit these pathways to improve ovarian cancer treatment. Wed, 16 Mar 2022 14:58:27 EDT //www.koonmotors.com/releases/2022/03/220316145827.htm //www.koonmotors.com/releases/2022/03/220315121442.htm Researchers have demonstrated a genetic link between endometriosis and ovarian cancer subtypes enabling them to identify potential drug targets for therapy and increasing the understanding of both diseases. Tue, 15 Mar 2022 12:14:42 EDT //www.koonmotors.com/releases/2022/03/220315121442.htm //www.koonmotors.com/releases/2022/03/220308102752.htm Women who have had one ovary surgically removed (unilateral oophorectomy) are less likely to become pregnant after in vitro fertilization and give birth to fewer babies than women with both ovaries. That is according to an extensive meta-analysis. Tue, 08 Mar 2022 10:27:52 EST //www.koonmotors.com/releases/2022/03/220308102752.htm //www.koonmotors.com/releases/2022/02/220223143453.htm A discovery made in a new study helps to identify poor response tumors already prior chemotherapy is applied and opens new avenues for the development of combination therapies. Wed, 23 Feb 2022 14:34:53 EST //www.koonmotors.com/releases/2022/02/220223143453.htm //www.koonmotors.com/releases/2022/02/220214183325.htm A new study shows ixabepilone plus bevacizumab (IXA+BEV) is a well-tolerated, effective combination for treatment of platinum/taxane-resistant ovarian cancer compared to ixabepilone (IXA) alone. Mon, 14 Feb 2022 18:33:25 EST //www.koonmotors.com/releases/2022/02/220214183325.htm //www.koonmotors.com/releases/2022/02/220211102631.htm Researchers discovered how ovarian cancer hides from the body's immune system. The findings will help develop novel precision therapies for ovarian cancer, a common and aggressive cancer type. Fri, 11 Feb 2022 10:26:31 EST //www.koonmotors.com/releases/2022/02/220211102631.htm //www.koonmotors.com/releases/2021/09/210921125103.htm Mutations in the ARID1A gene are present in more than 50% of ovarian clear cell carcinomas (OCCC), for which effective treatments are lacking. Scientists discovered that loss of ARID1A function enhances a cellular stress response pathway that promotes survival of cancer cells, which become sensitive to pharmacological inhibition of this pathway. Tue, 21 Sep 2021 12:51:03 EDT //www.koonmotors.com/releases/2021/09/210921125103.htm //www.koonmotors.com/releases/2021/08/210805154731.htm 一种叫做DOT1L似乎在食物中发挥作用ression and severity of ovarian cancer, and inhibitors of the DOT1L enzyme may offer a new therapeutic approach for the disease, researchers say in a new study. The need is clear -- despite decades of work to develop new treatment modalities, the five-year survival of patients with advanced ovarian cancer is between 10 and 30 percent. Thu, 05 Aug 2021 15:47:31 EDT //www.koonmotors.com/releases/2021/08/210805154731.htm //www.koonmotors.com/releases/2021/08/210803121318.htm A key element to slowing metastasis in ovarian cancer is understanding the mechanisms of how tumor cells invade tissues. Biophysics researchers explain how microscopic defects in how healthy cells line up can alter how easily ovarian cancer cells invade tissue. Using an experimental model, the group found that disruptions in the normal cellular layout, called topological defects, affect the rate of tumor cell invasion. Tue, 03 Aug 2021 12:13:18 EDT //www.koonmotors.com/releases/2021/08/210803121318.htm //www.koonmotors.com/releases/2021/07/210729143419.htm Researchers report the identification of a new target for the PARP inhibitor drug talazoparib and show that combination treatment with talazoparib and the WEE1 inhibitor adavosertib results in enhanced anti-cancer effects. Thu, 29 Jul 2021 14:34:19 EDT //www.koonmotors.com/releases/2021/07/210729143419.htm //www.koonmotors.com/releases/2021/07/210723154527.htm Researchers are pushing organ-on-a-chip devices to new levels that could change the way clinicians approach cancer treatment, particularly ovarian cancer. Fri, 23 Jul 2021 15:45:27 EDT //www.koonmotors.com/releases/2021/07/210723154527.htm //www.koonmotors.com/releases/2021/06/210601121755.htm An odor-based test that sniffs out vapors emanating from blood samples was able to distinguish between benign and pancreatic and ovarian cancer cells with up to 95% accuracy. Tue, 01 Jun 2021 12:17:55 EDT //www.koonmotors.com/releases/2021/06/210601121755.htm //www.koonmotors.com/releases/2021/03/210318142432.htm A study looked into how CAR T immunotherapy could be used to treat solid tumors in addition to leukemias. The programming of CAR T cells opens avenues for applying cell therapies to, for example, breast cancer or ovarian cancer in the future. Thu, 18 Mar 2021 14:24:32 EDT //www.koonmotors.com/releases/2021/03/210318142432.htm //www.koonmotors.com/releases/2021/02/210203144530.htm Researchers demonstrate why some ovarian cancer patients evolve better than others and suggest possible approaches to improve patient outcomes. Wed, 03 Feb 2021 14:45:30 EST //www.koonmotors.com/releases/2021/02/210203144530.htm //www.koonmotors.com/releases/2021/01/210107135655.htm Improving imaging processes will lead to more successful treatments and help reduce morbidity in men with the disease. Thu, 07 Jan 2021 13:56:55 EST //www.koonmotors.com/releases/2021/01/210107135655.htm //www.koonmotors.com/releases/2021/01/210106095314.htm A new advanced computing technique using routine medical scans to enable doctors to take fewer, more accurate tumor biopsies, has been developed by cancer researchers. This is an important step towards precision tissue sampling for cancer patients to help select the best treatment. In future the technique could even replace clinical biopsies with 'virtual biopsies', sparing patients invasive procedures. Wed, 06 Jan 2021 09:53:14 EST //www.koonmotors.com/releases/2021/01/210106095314.htm //www.koonmotors.com/releases/2020/12/201217090406.htm A comprehensive study involving more than 250,000 women, shows that oral contraceptive use protects against ovarian and endometrial cancer. The protective effect remains for several decades after discontinuing the use. Thu, 17 Dec 2020 09:04:06 EST //www.koonmotors.com/releases/2020/12/201217090406.htm //www.koonmotors.com/releases/2020/09/200925113335.htm 女性接受fertility-sparing手术对胎面tment of borderline ovarian tumors were able to have children, a new study shows. Fri, 25 Sep 2020 11:33:35 EDT //www.koonmotors.com/releases/2020/09/200925113335.htm //www.koonmotors.com/releases/2020/09/200911110749.htm Scientists have pinpointed which specific genes drive - or delay - high-grade serious ovarian carcinoma. Fri, 11 Sep 2020 11:07:49 EDT //www.koonmotors.com/releases/2020/09/200911110749.htm //www.koonmotors.com/releases/2020/08/200824105555.htm A new two-stage surgical approach for cancer prevention is highly acceptable among premenopausal women at high risk of ovarian cancer. Mon, 24 Aug 2020 10:55:55 EDT //www.koonmotors.com/releases/2020/08/200824105555.htm //www.koonmotors.com/releases/2020/08/200817104249.htm 全球的医疗研究小组由新南威尔士大学have developed a test that could help to predict survival for women diagnosed with ovarian cancer, and pave the way towards personalised treatment. Mon, 17 Aug 2020 10:42:49 EDT //www.koonmotors.com/releases/2020/08/200817104249.htm //www.koonmotors.com/releases/2020/08/200805110125.htm Medical researchers provide new insights into how ovarian cancer grows and evolves within a person. Wed, 05 Aug 2020 11:01:25 EDT //www.koonmotors.com/releases/2020/08/200805110125.htm //www.koonmotors.com/releases/2020/07/200727154201.htm Researchers report that inhibiting a key enzyme caused human cancer cells associated with two major types of breast and ovarian cancer to die and in mouse studies reduced tumor growth. Mon, 27 Jul 2020 15:42:01 EDT //www.koonmotors.com/releases/2020/07/200727154201.htm //www.koonmotors.com/releases/2020/07/200716220926.htm Screening entire populations for breast and ovarian cancer gene mutations could prevent millions more breast and ovarian cancer cases across the world compared to current clinical practice, according to an international study. The research also shows that it is cost effective in high and upper-middle income countries. Thu, 16 Jul 2020 22:09:26 EDT //www.koonmotors.com/releases/2020/07/200716220926.htm //www.koonmotors.com/releases/2020/07/200708105811.htm A follow-up study of almost 20,000 young women who had a first cycle of IVF in Denmark between 1995 and 2014 indicates that those who responded poorly to treatment, with few eggs collected, are at a significantly increased risk of later age-related diseases. Wed, 08 Jul 2020 10:58:11 EDT //www.koonmotors.com/releases/2020/07/200708105811.htm //www.koonmotors.com/releases/2020/06/200615184158.htm Berzosertib, an ATR-targeting drug, improves progression-free survival in combination with chemotherapy in patients with high-grade serous ovarian cancer. Mon, 15 Jun 2020 18:41:58 EDT //www.koonmotors.com/releases/2020/06/200615184158.htm //www.koonmotors.com/releases/2020/05/200501133849.htm Certain genetic changes, termed 'pathogenic variants,' substantially increase risk for cardiovascular disease and cancer--the leading causes of death -- but testing to identify individual carriers is not part of current clinical practice. Fri, 01 May 2020 13:38:49 EDT //www.koonmotors.com/releases/2020/05/200501133849.htm //www.koonmotors.com/releases/2020/03/200302103737.htm Researchers have analyzed all cell types in the human ovary and found that the hotly debated so-called egg stem cells do not exist. Mon, 02 Mar 2020 10:37:37 EST //www.koonmotors.com/releases/2020/03/200302103737.htm //www.koonmotors.com/releases/2020/01/200130144436.htm Infertility likely stems from age-related decline of the ovaries, but the molecular mechanisms that lead to this decline have been unclear. Now, scientists have discovered, in unprecedented detail, how ovaries age in non-human primates. The findings reveal several genes that could be used as biomarkers and point to therapeutic targets for diagnosing and treating female infertility and age-associated ovarian diseases, such as ovarian cancer, in humans. Thu, 30 Jan 2020 14:44:36 EST //www.koonmotors.com/releases/2020/01/200130144436.htm //www.koonmotors.com/releases/2020/01/200123114658.htm Researchers have discovered a two-drug combo that halts the growth of cancer cells that carry HER2 mutations. Thu, 23 Jan 2020 11:46:58 EST //www.koonmotors.com/releases/2020/01/200123114658.htm //www.koonmotors.com/releases/2020/01/200106124333.htm For the first time, scientists identified and mapped the location of structural proteins in a pig ovary. Ongoing development of an 'ink' with these proteins will be used for 3-D printing an artificial (or bio-prosthetic) ovary that could be implanted and allow a woman to have a child. Mon, 06 Jan 2020 12:43:33 EST //www.koonmotors.com/releases/2020/01/200106124333.htm //www.koonmotors.com/releases/2019/10/191009101146.htm A laboratory study offers a new hypothesis about how ovarian cancer forms and suggests how it might be prevented. The study is the first to show that the natural stiffening of the ovaries called fibrosis occurs with age. It also suggests that the diabetes drug metformin may be able to halt this process. Wed, 09 Oct 2019 10:11:46 EDT //www.koonmotors.com/releases/2019/10/191009101146.htm //www.koonmotors.com/releases/2019/09/190906090553.htm The ARID1A tumor suppressor protein is required to maintain telomere cohesion and correct chromosome segregation after DNA replication. This finding indicates that ARID1A-mutated cells undergo gross genomic alterations that are not compatible with survival and explains the lack of genomic instability characteristic of ARID1A-mutated cancers. Fri, 06 Sep 2019 09:05:53 EDT //www.koonmotors.com/releases/2019/09/190906090553.htm //www.koonmotors.com/releases/2019/09/190905094044.htm Women who experienced six or more symptoms of post-traumatic stress disorder (PTSD) at some point in life had a twofold greater risk of developing ovarian cancer compared with women who never had any PTSD symptoms, according to a new study. Thu, 05 Sep 2019 09:40:44 EDT //www.koonmotors.com/releases/2019/09/190905094044.htm //www.koonmotors.com/releases/2019/09/190903173403.htm A new study links changes in the gene for the protein focal adhesion kinase, or FAK, to ovarian cancer's ability to survive chemotherapy. Tue, 03 Sep 2019 17:34:03 EDT //www.koonmotors.com/releases/2019/09/190903173403.htm //www.koonmotors.com/releases/2019/07/190725092506.htm Delivering two federally approved immunity-altering drugs together significantly extended the lives of mice injected with human ovarian cancer cells, an early proof-of-concept experiment that may advance treatment for the most deadly -- although rare -- gynecologic malignancy in humans. Thu, 25 Jul 2019 09:25:06 EDT //www.koonmotors.com/releases/2019/07/190725092506.htm //www.koonmotors.com/releases/2019/07/190724144148.htm Biomedical engineers have discovered a method to track down and kill escaping cancer cells during tumor removal surgeries. The method, which uses the body's own defenses in the form of modified lipid nanoparticles adhered to white blood cells, could preventing metastasis and save lives. Wed, 24 Jul 2019 14:41:48 EDT //www.koonmotors.com/releases/2019/07/190724144148.htm //www.koonmotors.com/releases/2019/07/190715114245.htm A new study argues against combined approach: Patients undergoing coordinated breast and gynecologic procedures had a significantly longer length of hospital stay, and higher complication, readmission, and reoperation rates compared with patients who underwent single site surgery. Mon, 15 Jul 2019 11:42:45 EDT //www.koonmotors.com/releases/2019/07/190715114245.htm //www.koonmotors.com/releases/2019/07/190712105720.htm Preventing a protein from doing its job may keep a certain type of ovarian cancer cell from growing and dividing uncontrollably in the lab, according to a new study. Fri, 12 Jul 2019 10:57:20 EDT //www.koonmotors.com/releases/2019/07/190712105720.htm //www.koonmotors.com/releases/2019/07/190709160134.htm In a new study, researchers have shown the key role that a protein called Ran plays in the mobility of ovarian cancer cells. They demonstrated these cells cannot migrate from cancerous sites without the help of Ran. Tue, 09 Jul 2019 16:01:34 EDT //www.koonmotors.com/releases/2019/07/190709160134.htm //www.koonmotors.com/releases/2019/07/190708131148.htm Women who knew their BRCA+ status were diagnosed with earlier stage breast cancer, needed less chemotherapy, less extensive surgery, and had greater overall 5-year survival (98 percent vs. 74 percent). Mon, 08 Jul 2019 13:11:48 EDT //www.koonmotors.com/releases/2019/07/190708131148.htm //www.koonmotors.com/releases/2019/06/190626171231.htm Researchers have developed an improved technique for using magnetic nanoclusters to kill hard-to-reach tumors. Wed, 26 Jun 2019 17:12:31 EDT //www.koonmotors.com/releases/2019/06/190626171231.htm //www.koonmotors.com/releases/2019/06/190611081901.htm Researchers have developed a two-step combination therapy to destroy cancer cells. They show the superior therapeutic effectiveness of the 'one-two punch' on cells of ovarian cancer patients, based on manipulation of the state of cellular aging. Tue, 11 Jun 2019 08:19:01 EDT //www.koonmotors.com/releases/2019/06/190611081901.htm