//www.koonmotors.com/news/health_medicine/malaria/ Malaria research. Read the latest medical research on malaria, including new control methods and malaria treatments. en-us Fri, 08 Sep 2023 12:15:27 EDT Fri, 08 Sep 2023 12:15:27 EDT 60 //www.koonmotors.com/images/scidaily-logo-rss.png//www.koonmotors.com/news/health_medicine/malaria/ For more science news, visit ScienceDaily. //www.koonmotors.com/releases/2023/08/230828162349.htm Findings can open up new avenues for targeted approaches toward therapeutic strategies against the malaria-causing P. falciparum that are aimed at stopping the parasite's life cycle progression and its sexual differentiation, thus blocking the transmission of the parasite into mosquitoes. Mon, 28 Aug 2023 16:23:49 EDT //www.koonmotors.com/releases/2023/08/230828162349.htm //www.koonmotors.com/releases/2023/08/230811115456.htm Specific receptors in the ears of mosquitoes have been revealed to modulate their hearing, finds a new study. Scientists say, this discovery could help develop new insecticides and control the spread of harmful diseases, such as malaria. Fri, 11 Aug 2023 11:54:56 EDT //www.koonmotors.com/releases/2023/08/230811115456.htm //www.koonmotors.com/releases/2023/08/230811115433.htm An experimental malaria vaccine appears safe and promotes an immune response in African infants, one of the groups most vulnerable to severe malaria disease. There is currently only one malaria vaccine, 'RTS,S' that is approved by the World Health Organization and offers partial disease protection. However, in the results of the early-stage phase Ib trial, researchers find that targeting RH5 -- a protein that the malaria pathogen Plasmodium falciparum uses to invade red blood cells -- can generate a promising immune response that is most pronounced in an infant cohort. Fri, 11 Aug 2023 11:54:33 EDT //www.koonmotors.com/releases/2023/08/230811115433.htm //www.koonmotors.com/releases/2023/08/230808181913.htm 新研究发现,体内炎症can slow down the development of malaria parasites in the bloodstream -- a discovery that may constitute a potential new strategy for preventing or limiting severe disease. 星期二,2023年8月08年18:19:13美国东部时间 //www.koonmotors.com/releases/2023/08/230808181913.htm //www.koonmotors.com/releases/2023/07/230720124846.htm A new mRNA vaccine targeting immune cells in the liver could be the key to tackling malaria, a disease that causes over half a million deaths each year according to the World Health Organization, yet has no effective long-lasting vaccine. Thu, 20 Jul 2023 12:48:46 EDT //www.koonmotors.com/releases/2023/07/230720124846.htm //www.koonmotors.com/releases/2023/07/230705154012.htm Using CRISPR technology, scientists have engineered a new way to genetically suppress populations of Anopheles gambiae, the mosquitoes that primarily spread malaria in Africa and contribute to economic poverty in affected regions. Wed, 05 Jul 2023 15:40:12 EDT //www.koonmotors.com/releases/2023/07/230705154012.htm //www.koonmotors.com/releases/2023/06/230606164816.htm Could the next weapon against malaria come from a better understanding of biological clocks? A new study shows that malaria parasites sync their gene activity with the circadian rhythms of their host, like two pendulum clocks with synchronized swings. If scientists can identify the molecular signals behind this mysterious synchronicity, they might be able to develop new anti-malarial drugs that throw malaria's internal clock out of step with its host, essentially 'jet-lagging' the parasites. Tue, 06 Jun 2023 16:48:16 EDT //www.koonmotors.com/releases/2023/06/230606164816.htm //www.koonmotors.com/releases/2023/05/230511164547.htm Much of what is now considered modern medicine originated as folk remedies or traditional, Indigenous practices. These customs are still alive today, and they could help address a variety of conditions. Now, researchers have identified compounds in the leaves of a particular medicinal Labrador tea plant used throughout the First Nations of Nunavik, Canada, and demonstrated that one of them has activity against the parasite responsible for malaria. Thu, 11 May 2023 16:45:47 EDT //www.koonmotors.com/releases/2023/05/230511164547.htm //www.koonmotors.com/releases/2023/04/230404114232.htm With dengue on the spread, the new discovery helps explain why dengue viruses are so easily transmitted. The finding could also lead to new ways to prevent infection. Tue, 04 Apr 2023 11:42:32 EDT //www.koonmotors.com/releases/2023/04/230404114232.htm //www.koonmotors.com/releases/2023/03/230322082801.htm A mosquito known only by its scientific name, Culex lactator, is the latest to establish in the Sunshine State, according to a new study. Wed, 22 Mar 2023 08:28:01 EDT //www.koonmotors.com/releases/2023/03/230322082801.htm //www.koonmotors.com/releases/2023/03/230321112138.htm Malaria control programs in Amazonian Peru helped reduce the incidence of the deadly parasitic disease by 78 percent. That is, until the programs ceased to operate. Within four years of the programs being de-funded, malaria rates where right back where they started. The rebound was driven not only by the removal of prevention programs, but also by climate change. Average temperatures in Peru have risen a half-degree Centigrade in the last 20 years. Tue, 21 Mar 2023 11:21:38 EDT //www.koonmotors.com/releases/2023/03/230321112138.htm //www.koonmotors.com/releases/2023/03/230316114100.htm New research makes it likely that proteins responsible for activating mosquito sperm can be shut down, preventing them from swimming to or fertilizing eggs. Thu, 16 Mar 2023 11:41:00 EDT //www.koonmotors.com/releases/2023/03/230316114100.htm //www.koonmotors.com/releases/2023/03/230313120931.htm A new study has?highlighted?how and when?changes to the environment result in?animal-borne disease?thresholds?being breeched, allowing for?a?better understanding and?increased?capacity to?predict?the?risk of?transmissions. Mon, 13 Mar 2023 12:09:31 EDT //www.koonmotors.com/releases/2023/03/230313120931.htm //www.koonmotors.com/releases/2023/02/230222210539.htm A new study integrates climate, land use, and socioeconomic data to explain and predict malaria dynamics at the village level. The approach could inform health care practitioners and make control strategies more efficient and cost-effective. Wed, 22 Feb 2023 21:05:39 EST //www.koonmotors.com/releases/2023/02/230222210539.htm //www.koonmotors.com/releases/2023/02/230221113012.htm 为了理解为什么蚊子可能更多attracted to one human than another, researchers say they have mapped specialized receptors on the insects' nerve cells that are able to fine-tune their ability to detect particularly 'welcoming' odors in human skin. Tue, 21 Feb 2023 11:30:12 EST //www.koonmotors.com/releases/2023/02/230221113012.htm //www.koonmotors.com/releases/2023/02/230209094201.htm Bioengineers and experts in tropical medicine have invented a new way of studying mosquito feeding behavior using technology instead of live volunteers. Their open-source design combines automated cameras, artificial intelligence and blood-infused, 3D-printed 'synthetic skin.' Thu, 09 Feb 2023 09:42:01 EST //www.koonmotors.com/releases/2023/02/230209094201.htm //www.koonmotors.com/releases/2023/01/230109112747.htm Parasitologists have shown that a complex of two protein variants plays a significant role in toxoplasmosis infection. Mon, 09 Jan 2023 11:27:47 EST //www.koonmotors.com/releases/2023/01/230109112747.htm //www.koonmotors.com/releases/2023/01/230104135612.htm A three-dose regimen of a whole-parasite vaccine against malaria -- called Plasmodium falciparum sporozoite (PfSPZ) vaccine -- demonstrated safety and efficacy when tested in adults living in Burkina Faso, West Africa, which has endemic malaria. Wed, 04 Jan 2023 13:56:12 EST //www.koonmotors.com/releases/2023/01/230104135612.htm //www.koonmotors.com/releases/2022/12/221220113023.htm A large-scale study has found that rectal artesunate (RAS) has no beneficial effect on the survival of young children with severe malaria when used as an emergency treatment in resource-constrained settings. The study, which took place under real-world conditions in three African countries, concludes that the use of RAS is unlikely to reduce malaria deaths unless underlying health system weaknesses are addressed. Tue, 20 Dec 2022 11:30:23 EST //www.koonmotors.com/releases/2022/12/221220113023.htm //www.koonmotors.com/releases/2022/12/221209094743.htm A fast, needle-free malaria detection tool could help save hundreds of thousands of lives annually. Fri, 09 Dec 2022 09:47:43 EST //www.koonmotors.com/releases/2022/12/221209094743.htm //www.koonmotors.com/releases/2022/12/221206105903.htm A new antimalarial drug is being introduced at a dose that is too low to be effective for all patients who need it, according to a new report. Tue, 06 Dec 2022 10:59:03 EST //www.koonmotors.com/releases/2022/12/221206105903.htm //www.koonmotors.com/releases/2022/12/221201082140.htm A study shows that the new mRNA technology could help researchers save millions of lives, prevent illness and make progress toward elimination of this ancient disease. Thu, 01 Dec 2022 08:21:40 EST //www.koonmotors.com/releases/2022/12/221201082140.htm //www.koonmotors.com/releases/2022/11/221115114109.htm Male mosquitoes find mates by listening for the buzzing sounds produced by flying females. Now researchers have developed a technique using a serotonin inhibiting compound that disrupts the hearing of male mosquitoes. This prevents them from finding a mate and may offer a new way to reduce mosquito populations. Tue, 15 Nov 2022 11:41:09 EST //www.koonmotors.com/releases/2022/11/221115114109.htm //www.koonmotors.com/releases/2022/11/221101100739.htm One dose of an antibody drug safely protected healthy, non-pregnant adults from malaria infection during an intense six-month malaria season in Mali, Africa, a National Institutes of Health clinical trial has found. The antibody was up to 88.2% effective at preventing infection over a 24-week period, demonstrating for the first time that a monoclonal antibody can prevent malaria infection in an endemic region. Tue, 01 Nov 2022 10:07:39 EDT //www.koonmotors.com/releases/2022/11/221101100739.htm //www.koonmotors.com/releases/2022/10/221027124001.htm The female mosquito will hunt down any human, but some of us get bitten far more than others. The answer why may be hidden in our skin. Thu, 27 Oct 2022 12:40:01 EDT //www.koonmotors.com/releases/2022/10/221027124001.htm //www.koonmotors.com/releases/2022/09/220926090217.htm Combining microbiology with engineering technologies, this novel 3D model uses a single microfluidic chip to study the complicated processes that take place in malaria-infected placenta as well as other placenta-related diseases and pathologies. The technology supports formation of microengineered placental barriers and mimics blood circulations, which provides alternative approaches for testing and screening. Mon, 26 Sep 2022 09:02:17 EDT //www.koonmotors.com/releases/2022/09/220926090217.htm //www.koonmotors.com/releases/2022/09/220921141449.htm Scientists have engineered mosquitoes that slow the growth of malaria-causing parasites in their gut, preventing transmission of the disease to humans. Wed, 21 Sep 2022 14:14:49 EDT //www.koonmotors.com/releases/2022/09/220921141449.htm //www.koonmotors.com/releases/2022/09/220920141416.htm A new study links an amphibian die-off in Costa Rica and Panama with a spike in malaria cases. The study demonstrates the importance of biodiversity to human health. Tue, 20 Sep 2022 14:14:16 EDT //www.koonmotors.com/releases/2022/09/220920141416.htm //www.koonmotors.com/releases/2022/08/220812224152.htm Rearchers have created a mathematical model to predict genetic resistance to antimalarial drugs in Africa to manage one of the biggest threats to global malarial control. Fri, 12 Aug 2022 22:41:52 EDT //www.koonmotors.com/releases/2022/08/220812224152.htm //www.koonmotors.com/releases/2022/08/220804102622.htm One injection of a candidate monoclonal antibody (mAb) known as L9LS was found to be safe and highly protective in U.S. adults exposed to the malaria parasite, according to new results. Additional clinical trials evaluating if L9LS can prevent malaria over six to 12 months against seasonal and perennial transmission are underway in infants and children in Mali and Kenya, where malaria is endemic. Thu, 04 Aug 2022 10:26:22 EDT //www.koonmotors.com/releases/2022/08/220804102622.htm //www.koonmotors.com/releases/2022/07/220728143033.htm Scientists have made a major breakthrough in understanding how malaria parasites divide and transmit the disease, which could be a major step forwards in helping to prevent one of the biggest killer infections in the world. Thu, 28 Jul 2022 14:30:33 EDT //www.koonmotors.com/releases/2022/07/220728143033.htm //www.koonmotors.com/releases/2022/07/220719130234.htm Scientists report a new way to test vaccines that may be as rigorous and stringent as exposure to field strains of malaria. Tue, 19 Jul 2022 13:02:34 EDT //www.koonmotors.com/releases/2022/07/220719130234.htm //www.koonmotors.com/releases/2022/07/220707100937.htm Increases in three climate factors -- temperature, rainfall, and ocean warming -- predicted mosquito population growth in Sri Lanka for the next one to six months, according to a new study. The findings can inform the design and timing of programs to limit the spread of mosquito-borne diseases like dengue. Thu, 07 Jul 2022 10:09:37 EDT //www.koonmotors.com/releases/2022/07/220707100937.htm //www.koonmotors.com/releases/2022/06/220630114511.htm Zika and dengue fever viruses alter the scent of mice and humans they infect, a team of researchers report. The altered scent attracts mosquitoes, which bite the host, drink their infected blood and then carry the virus to its next victim. Thu, 30 Jun 2022 11:45:11 EDT //www.koonmotors.com/releases/2022/06/220630114511.htm //www.koonmotors.com/releases/2022/06/220617101813.htm Scientists have studied the human immune response after immunization with the malaria pathogen Plasmodium falciparum. Their findings could explain why natural infections, to which people in endemic areas are constantly exposed, offer little protection against new diseases with other strains, and why the effect of the vaccination available to date lasts only a short time. Fri, 17 Jun 2022 10:18:13 EDT //www.koonmotors.com/releases/2022/06/220617101813.htm //www.koonmotors.com/releases/2022/06/220608161353.htm A molecule in mosquito spit has been identified as a potential new target for vaccination against a range of diseases for which there is no protection or medicine. Researchers have discovered that the molecule, called sialokinin, makes it easier for a number of viruses to pass from mosquitoes to human, where they can then take hold -- leading to unpleasant and potentially deadly diseases including Yellow Fewer, Dengue and Zika. Wed, 08 Jun 2022 16:13:53 EDT //www.koonmotors.com/releases/2022/06/220608161353.htm //www.koonmotors.com/releases/2022/06/220602140849.htm A new method to combat malaria which sees the disease turn against itself could offer an effective treatment for the hundreds of millions of people infected globally each year, as the efficacy of current antimalarial drugs weakens. The research has identified an anti-malarial compound, ML901, which inhibits the malaria parasite but does not harm mammalian -- human or other mammals' -- cells. Thu, 02 Jun 2022 14:08:49 EDT //www.koonmotors.com/releases/2022/06/220602140849.htm //www.koonmotors.com/releases/2022/06/220601111800.htm Turns out you're not the only one who needs a good night's rest to function well the next day. Researchers found that mosquitoes whose slumber is disrupted are more interested in catching up on their sleep than looking for food the next day. The research demonstrates how vital this biological function is even among insects. Wed, 01 Jun 2022 11:18:00 EDT //www.koonmotors.com/releases/2022/06/220601111800.htm //www.koonmotors.com/releases/2022/05/220513134859.htm Researchers managed to set larger groups of malaria parasites into motion and to analyze the acquired image data. The collectively moving pathogens form vortex systems that are largely determined by physical principles. Computer simulations helped identify the mechanisms underlying these rotating movements. Fri, 13 May 2022 13:48:59 EDT //www.koonmotors.com/releases/2022/05/220513134859.htm //www.koonmotors.com/releases/2022/05/220511102804.htm A new method blocks the protein regulation of the parasite Toxoplasma gondii and causes it to die off inside the host cell. Wed, 11 May 2022 10:28:04 EDT //www.koonmotors.com/releases/2022/05/220511102804.htm //www.koonmotors.com/releases/2022/05/220505085627.htm Researchers have made a crucial discovery about how asymptomatic malaria infections impact the body, informing potential strategies to control transmission and improve treatment outcomes. Thu, 05 May 2022 08:56:27 EDT //www.koonmotors.com/releases/2022/05/220505085627.htm //www.koonmotors.com/releases/2022/04/220420092126.htm Geoengineering the climate would have massive repercussions for the health of billions of people at risk of malaria who live in tropical countries, according to a new finding. This is the first assessment of how geoengineering the climate could impact the burden of infectious diseases. Wed, 20 Apr 2022 09:21:26 EDT //www.koonmotors.com/releases/2022/04/220420092126.htm //www.koonmotors.com/releases/2022/04/220419170752.htm Researchers have tracked Cryptosporidium in real time, creating a new paradigm for how the widespread parasite reproduces in a host. Tue, 19 Apr 2022 17:07:52 EDT //www.koonmotors.com/releases/2022/04/220419170752.htm //www.koonmotors.com/releases/2022/04/220419112516.htm By analysing samples from patients who have been treated for malaria in Sweden, researchers can now describe how the immune system acts to protect the body after a malaria infection. The results provide knowledge that can aid in the development of more effective vaccines against the disease. Tue, 19 Apr 2022 11:25:16 EDT //www.koonmotors.com/releases/2022/04/220419112516.htm //www.koonmotors.com/releases/2022/04/220419112514.htm Researchers developed a model to spatially distribute mosquitoes infected with Wolbachia bacteria, which reduce the transmission of the dengue virus. The researchers use real data on human and vector activity in a framework that can be analyzed from a mathematical point of view, allowing them to re-create and understand the epidemiological situation and identify those geographical areas with the greatest vulnerability, creating a ranking of areas that prioritizes those where Wolbachia-carrying mosquitoes can have the strongest and most beneficial impact on the spread of the virus. Tue, 19 Apr 2022 11:25:14 EDT //www.koonmotors.com/releases/2022/04/220419112514.htm //www.koonmotors.com/releases/2022/04/220419103236.htm Before being accidentally introduced to the New World by the 16th century slave trade, the yellow fever mosquito was a species native only to Africa. Highly adaptable, it has since become an invasive species in North America, but researchers at may have found a way to squash the pesky population in its juvenile stages. Tue, 19 Apr 2022 10:32:36 EDT //www.koonmotors.com/releases/2022/04/220419103236.htm //www.koonmotors.com/releases/2022/04/220406101658.htm Scientists have solved a 100-year-old mystery about the evolutionary links between malaria parasites that infect humans and chimpanzees. Wed, 06 Apr 2022 10:16:58 EDT //www.koonmotors.com/releases/2022/04/220406101658.htm //www.koonmotors.com/releases/2022/03/220325093920.htm A novel class of bed net that kills mosquitoes resistant to traditional insecticides by making them unable to move or fly, significantly reduces malaria infection in children, according to new research published in The Lancet. Unlike other insecticides which kill the mosquito via the nervous system, the effects of the new bed net mean the mosquito dies from starvation or being unable to fend for itself. Fri, 25 Mar 2022 09:39:20 EDT //www.koonmotors.com/releases/2022/03/220325093920.htm //www.koonmotors.com/releases/2022/03/220316132711.htm In what they call surprise findings, scientists report that -- unlike fruit flies -- mosquitoes' odor sensing nerve cells shut down when those cells are forced to produce odor-related proteins, or receptors, on the surface of the cell. This 'expression' process apparently makes the bugs able to ignore common insect repellents. Wed, 16 Mar 2022 13:27:11 EDT //www.koonmotors.com/releases/2022/03/220316132711.htm //www.koonmotors.com/releases/2022/02/220225100249.htm Malaria symptoms occur once the parasite's asexual stages begin replicating inside red blood cells. However, these asexual forms must transform into male and female stages called gametocytes in order to infect the mosquitoes that spread the disease. Investigators now report they have identified a protein called HDP1 that plays a critical role in activating genes required for the development of these male and female stages. The finding provides important new insights into how the parasite controls this conversion into gametocytes. Fri, 25 Feb 2022 10:02:49 EST //www.koonmotors.com/releases/2022/02/220225100249.htm //www.koonmotors.com/releases/2022/02/220225085901.htm A regional corner of Africa is a hotspot for cases of HIV, tuberculosis and malaria, prompting researchers to call for targeted health support rather than a national response. Fri, 25 Feb 2022 08:59:01 EST //www.koonmotors.com/releases/2022/02/220225085901.htm //www.koonmotors.com/releases/2022/02/220223104914.htm A new study has found diet, malaria, substance use and a lack of antenatal care services are linked to one in 10 babies in the Pacific Island region being born preterm and of low birth weight. Wed, 23 Feb 2022 10:49:14 EST //www.koonmotors.com/releases/2022/02/220223104914.htm //www.koonmotors.com/releases/2022/02/220222135133.htm The next generation of mosquito control might target the pests' reproductive genes. Researchers examined genetic material of three species of mosquito responsible for killing millions of people around the world each year. Researchers revealed the surprising genetic modifications female mosquitoes undergo, in part to create the next generation. Tue, 22 Feb 2022 13:51:33 EST //www.koonmotors.com/releases/2022/02/220222135133.htm //www.koonmotors.com/releases/2022/02/220217141207.htm An international team has discovered a protein that plays a key biological role in a parasite that causes malaria. Deactivating this protein reduces in vitro growth of Plasmodium falciparum, the protozoa behind the most virulent form of the disease, by more than 75%. Thu, 17 Feb 2022 14:12:07 EST //www.koonmotors.com/releases/2022/02/220217141207.htm //www.koonmotors.com/releases/2022/02/220202111811.htm The function of an enzyme, critical to most forms of life, has been revealed. Wed, 02 Feb 2022 11:18:11 EST //www.koonmotors.com/releases/2022/02/220202111811.htm //www.koonmotors.com/releases/2022/01/220126165521.htm Blocking a key protein found in Anopheles gambiae mosquitoes -- the principal vector for malaria transmission to humans in Africa -- could thwart infection with malaria parasites and thus prevent them from transmitting the parasites to humans, according to a new study. Wed, 26 Jan 2022 16:55:21 EST //www.koonmotors.com/releases/2022/01/220126165521.htm //www.koonmotors.com/releases/2022/01/220114192607.htm Using CRISPR/Cas9 technology, scientists have genetically engineered a method to reverse insecticide resistance. The gene replacement method offers a new way to fight deadly malaria spread and reduce the use of pesticides that protect valuable food crops. Fri, 14 Jan 2022 19:26:07 EST //www.koonmotors.com/releases/2022/01/220114192607.htm //www.koonmotors.com/releases/2022/01/220112145039.htm Male mosquitoes beat their wings faster when swarming at sunset to better detect females and increase their chance of reproducing, finds a novel study. Wed, 12 Jan 2022 14:50:39 EST //www.koonmotors.com/releases/2022/01/220112145039.htm //www.koonmotors.com/releases/2021/12/211215113223.htm Experts in Japan have identified a fundamental part of the immune system's long-term memory, providing a useful new detail in the pursuit to design better vaccines for diseases, ranging from COVID-19 to malaria. Wed, 15 Dec 2021 11:32:23 EST //www.koonmotors.com/releases/2021/12/211215113223.htm //www.koonmotors.com/releases/2021/12/211209124204.htm With an impressive capability of drinking up to three times their body weight in a single blood meal, mosquitoes are formidable parasites. But to reach adulthood, mosquitoes need to be raised in environments where the temperatures are conducive to their breeding, growth and development. Thu, 09 Dec 2021 12:42:04 EST //www.koonmotors.com/releases/2021/12/211209124204.htm