//www.koonmotors.com/news/health_medicine/lung_disease/ Latest medical research on lung disease. Learn about the symptoms of chronic obstructive pulmonary disease (COPD), emphysema, and lung cancer along with the latest treatment information. en-us Fri, 08 Sep 2023 08:16:17 EDT Fri, 08 Sep 2023 08:16:17 EDT 60 //www.koonmotors.com/images/scidaily-logo-rss.png//www.koonmotors.com/news/health_medicine/lung_disease/ For more science news, visit ScienceDaily. //www.koonmotors.com/releases/2023/09/230905124955.htm A new study has shown that a subtype of avian flu virus, endemic in poultry farms in China, is undergoing mutational changes, which could increase the risk of the disease being passed on to humans. Tue, 05 Sep 2023 12:49:55 EDT //www.koonmotors.com/releases/2023/09/230905124955.htm //www.koonmotors.com/releases/2023/08/230830131855.htm 最新发现的一种免疫细胞的计谋ld give lung cancer patients a more accurate prognosis and better identify who will benefit from immunotherapies. Researchers found that the location in and around tumours of cytotoxic T cells, which play a key role in fighting cancer, may help predict patient survival and indicate whether or not treatments will work. Wed, 30 Aug 2023 13:18:55 EDT //www.koonmotors.com/releases/2023/08/230830131855.htm //www.koonmotors.com/releases/2023/08/230825122019.htm High levels of some minerals and metals in environmental water supplies may increase the risk of nontuberculous mycobacteria (NTM) pulmonary infections in people with cystic fibrosis, according to a new study. The study found the presence of the metals molybdenum and vanadium along with sulfate -- a collection of mineral salts -- in the U.S. municipal water system was associated with an increased incidence of NTM pulmonary infections, the leading cause of drinking-water associated illnesses. Fri, 25 Aug 2023 12:20:19 EDT //www.koonmotors.com/releases/2023/08/230825122019.htm //www.koonmotors.com/releases/2023/08/230824111925.htm Researchers have discovered a novel approach for engrafting engineered cells into injured lung tissue. These findings may lead to new ways for treating lung diseases, such as emphysema, pulmonary fibrosis and COVID-19. The two studies describe the methodologies for engineering lung stem cells and transplanting them into injured experimental lungs without immunosuppression. Thu, 24 Aug 2023 11:19:25 EDT //www.koonmotors.com/releases/2023/08/230824111925.htm //www.koonmotors.com/releases/2023/08/230816114227.htm Researchers have found that molecules in vegetables like broccoli or cauliflower help to maintain a healthy barrier in the lung and ease infection. Wed, 16 Aug 2023 11:42:27 EDT //www.koonmotors.com/releases/2023/08/230816114227.htm //www.koonmotors.com/releases/2023/08/230811115519.htm Yoga and breathing control practices, in combination with aerobic training, are particularly key exercises for asthmatic people seeking to improve their lung function, a new peer-reviewed study suggests. Fri, 11 Aug 2023 11:55:19 EDT //www.koonmotors.com/releases/2023/08/230811115519.htm //www.koonmotors.com/releases/2023/08/230809130623.htm New findings may lead to relapse-free treatment for a sizeable subgroup of lung cancer patients. In a study in mice, scientists have identified a biomarker that may help physicians select lung cancer patients who can be treated with a single antibody-based drug that is likely to bring about full remission, without cancer relapse. Wed, 09 Aug 2023 13:06:23 EDT //www.koonmotors.com/releases/2023/08/230809130623.htm //www.koonmotors.com/releases/2023/08/230808110833.htm 过度活跃的免疫细胞背后往往肺damage in diseases such as Covid-19. Researchers have developed an RNA agent for a lung spray that slows the activity of these cells, known as macrophages. A new, sugar-based transport mechanism is especially effective in bringing the therapeutic to its target. Tue, 08 Aug 2023 11:08:33 EDT //www.koonmotors.com/releases/2023/08/230808110833.htm //www.koonmotors.com/releases/2023/07/230725123006.htm Having a food allergy as a baby is linked to asthma and reduced lung function later in childhood, according to a new study. Tue, 25 Jul 2023 12:30:06 EDT //www.koonmotors.com/releases/2023/07/230725123006.htm //www.koonmotors.com/releases/2023/07/230720124927.htm Omega-3 fatty acids, which are abundant in fish and fish oil supplements, appear promising for maintaining lung health, according to new evidence from a large, multi-faceted study in healthy adults. The study provides the strongest evidence to date of this association and underscores the importance of including omega-3 fatty acids in the diet, especially given that many Americans do not meet current guidelines. Thu, 20 Jul 2023 12:49:27 EDT //www.koonmotors.com/releases/2023/07/230720124927.htm //www.koonmotors.com/releases/2023/07/230707111622.htm The mucus in the airways is not as sticky, inflammation in the lungs significantly reduced: Triple combination therapy can achieve these positive, lasting effects in patients with cystic fibrosis (CF). According to new research, this form of medication improves the symptoms of CF in many patients. Fri, 07 Jul 2023 11:16:22 EDT //www.koonmotors.com/releases/2023/07/230707111622.htm //www.koonmotors.com/releases/2023/06/230622120900.htm Small-cell lung cancer is a particularly aggressive type of tumor with a consistently high mortality rate. In recent years, the research of scientists has significantly contributed to a better understanding and new therapeutic approaches in this malignant disease. Thu, 22 Jun 2023 12:09:00 EDT //www.koonmotors.com/releases/2023/06/230622120900.htm //www.koonmotors.com/releases/2023/06/230608120900.htm The largest and most comprehensive cell map of the human lung has been completed. The Human Lung Cell Atlas reveals the great diversity of cell types in the lung and shows key differences between health and disease. Researchers identified rare cell types and found common cell states between lung fibrosis, cancer and COVID-19, offering new ways of understanding lung disease, which could help identify new therapeutic targets. Thu, 08 Jun 2023 12:09:00 EDT //www.koonmotors.com/releases/2023/06/230608120900.htm //www.koonmotors.com/releases/2023/06/230601155927.htm Researchers have collaborated to refine a cell culture technology platform that grows genetically identical lung buds from human embryonic stem cells. Thu, 01 Jun 2023 15:59:27 EDT //www.koonmotors.com/releases/2023/06/230601155927.htm //www.koonmotors.com/releases/2023/05/230524181935.htm A new study has shown that human T cells have an important role to play in controlling infection. Wed, 24 May 2023 18:19:35 EDT //www.koonmotors.com/releases/2023/05/230524181935.htm //www.koonmotors.com/releases/2023/04/230421092159.htm Storing donor lungs for transplant at 10 degrees Celsius markedly increases the length of time the organ can live outside the body according to new research. Fri, 21 Apr 2023 09:21:59 EDT //www.koonmotors.com/releases/2023/04/230421092159.htm //www.koonmotors.com/releases/2023/03/230331120636.htm A new type of nanoparticle can be administered to the lungs, where it can deliver messenger RNA encoding useful proteins. Researchers hope to use them to develop new treatments for cystic fibrosis and other lung diseases. Fri, 31 Mar 2023 12:06:36 EDT //www.koonmotors.com/releases/2023/03/230331120636.htm //www.koonmotors.com/releases/2023/03/230328145216.htm Researchers develop a 3D cell culture system to test how inhibiting fibroblast activities can help treat lung cancer. To simulate the tumor microenvironment and mimic real tissues, the team co-cultured lung cancer cells and fibroblasts in a 3D matrix. The researchers then tested the anti-cancer drug cisplatin with and without two anti-fibrotic drugs, nintedanib and pirfenidone. They found that combining the anti-fibrotic drug nintedanib with the anti-cancer drug cisplatin increased the efficacy of the latter. Tue, 28 Mar 2023 14:52:16 EDT //www.koonmotors.com/releases/2023/03/230328145216.htm //www.koonmotors.com/releases/2023/03/230317184940.htm A new study has revealed FDA-approved trametinib and entinostat (which is currently in clinical trials) can be given in tandem to produce fewer and smaller tumors in mice with LKB1-mutated non-small cell lung cancer. Fri, 17 Mar 2023 18:49:40 EDT //www.koonmotors.com/releases/2023/03/230317184940.htm //www.koonmotors.com/releases/2023/03/230315132413.htm A new study represents a first step towards generating highly detailed 3-dimensional maps of lung tumors using genetically engineered mouse models. Wed, 15 Mar 2023 13:24:13 EDT //www.koonmotors.com/releases/2023/03/230315132413.htm //www.koonmotors.com/releases/2023/03/230313120939.htm Scientists have discovered why breast cancer cells that have spread to the lungs may 'wake up' following years of sleep -- forming incurable secondary tumors. Their research reveals the mechanism that triggers this breast cancer 'time bomb' -- and suggests a strategy to defuse it. Mon, 13 Mar 2023 12:09:39 EDT //www.koonmotors.com/releases/2023/03/230313120939.htm //www.koonmotors.com/releases/2023/03/230310123846.htm 每10个成人中就有一人患有衰弱了cts of chronic obstructive pulmonary disease (COPD). Research around a new breathing device developed by pulmonologists offers promise for improving their lives. The new device not only improves symptoms of breathlessness and quality of life for people with COPD, it also offers benefits for people dealing with stress and anxiety and those practicing mindfulness, meditation or yoga. The research was published in the journal Respiratory Care. Fri, 10 Mar 2023 12:38:46 EST //www.koonmotors.com/releases/2023/03/230310123846.htm //www.koonmotors.com/releases/2023/03/230309101341.htm Congenital diaphragmatic hernia is one of the deadliest birth defects. To better understand and treat this condition in the future, researchers designed a new cell model in the laboratory and tested a drug therapy on it. Thu, 09 Mar 2023 10:13:41 EST //www.koonmotors.com/releases/2023/03/230309101341.htm //www.koonmotors.com/releases/2023/03/230308084404.htm Contracting a lower respiratory tract infection in early childhood is associated with a higher risk of dying from respiratory disease as an adult, according to new research. Wed, 08 Mar 2023 08:44:04 EST //www.koonmotors.com/releases/2023/03/230308084404.htm //www.koonmotors.com/releases/2023/02/230227132605.htm New research reveals how the relationship between nerves and immune cells in the lungs can contribute to the development of allergic asthma. Mon, 27 Feb 2023 13:26:05 EST //www.koonmotors.com/releases/2023/02/230227132605.htm //www.koonmotors.com/releases/2023/02/230223132835.htm 在斯德哥尔摩空气污染减少了,哈哈s the lung capacity of children and adolescents has improved, a new study reports. The researchers consider the results important, since the lung health of the young greatly affects the risk of their developing chronic lung diseases later in life. Thu, 23 Feb 2023 13:28:35 EST //www.koonmotors.com/releases/2023/02/230223132835.htm //www.koonmotors.com/releases/2023/02/230222141131.htm A new study uncovers how a protein, APOBEC3B, could protects cells against many different types of RNA viruses like respiratory syncytial virus (RSV), SARS-CoV2, influenza virus, poliovirus and measles, helping to prevent disease. Wed, 22 Feb 2023 14:11:31 EST //www.koonmotors.com/releases/2023/02/230222141131.htm //www.koonmotors.com/releases/2023/02/230208125111.htm A new study reveals how resistance to bacteraemic pneumonia is provided by a unique subset of lung T regulatory cells. Wed, 08 Feb 2023 12:51:11 EST //www.koonmotors.com/releases/2023/02/230208125111.htm //www.koonmotors.com/releases/2023/01/230131183139.htm New data from a clinical trial shows improved rates of survival and reduced risk of recurrence in patients taking osimertinib, a targeted therapy for non-small cell lung cancer (NSCLC). Tue, 31 Jan 2023 18:31:39 EST //www.koonmotors.com/releases/2023/01/230131183139.htm //www.koonmotors.com/releases/2023/01/230119112740.htm Researchers demonstrate that a bacteria can be modified to act as 'living medicine' in the lung. The treatment significantly reduced acute lung infections in mice and doubled their survival rate. It showed no signs of toxicity in the lungs and once the treatment had finished its course, it was cleared by the immune system in a period of four days. The treatment also cleared biofilms that accumulate on the surface of endotracheal tubes used by patients with ventilator-associated pneumonia, which is one of the leading causes of mortality in intensive care units. The study paves the way for researchers to repurpose the bacteria to treat other types of lung diseases such as cancer, asthma or pulmonary fibrosis. Thu, 19 Jan 2023 11:27:40 EST //www.koonmotors.com/releases/2023/01/230119112740.htm //www.koonmotors.com/releases/2023/01/230112113203.htm More than 2,500 genes exhibit significant sex differences in expression in mouse alveolar type II cells (AT2s), important for keeping the lungs functioning, potentially explaining sex biases in the prevalence and severity of lung diseases. In particular, very high numbers of X-linked genes escape transcriptional silencing in lung alveolar type 2 (AT2s) cells, researchers report. Thu, 12 Jan 2023 11:32:03 EST //www.koonmotors.com/releases/2023/01/230112113203.htm //www.koonmotors.com/releases/2023/01/230109112729.htm A new study found that deleting a gene called KMT2D caused normal (basal) lung cells grown in complex cultures called organoids to transform into lung squamous carcinoma (LUSC) cells. Mon, 09 Jan 2023 11:27:29 EST //www.koonmotors.com/releases/2023/01/230109112729.htm //www.koonmotors.com/releases/2023/01/230105151236.htm A new method of donor-lung distribution is projected to decrease the number of candidate deaths who are on the waitlist for lung transplant, according to a new study. Thu, 05 Jan 2023 15:12:36 EST //www.koonmotors.com/releases/2023/01/230105151236.htm //www.koonmotors.com/releases/2022/12/221229115715.htm A research team has shown that Sarunashi juice and its constituting component isoquercetin help prevent and reduce lung cancer in laboratory mice. Thu, 29 Dec 2022 11:57:15 EST //www.koonmotors.com/releases/2022/12/221229115715.htm //www.koonmotors.com/releases/2022/12/221228130409.htm Researchers have found that antigen-specific killer T cells (CD8+ T cells) rapidly expand in the lungs when primed by antigen-presenting lung-resident alveolar macrophages (AMs). This interaction helps protect against viral infection and could form the basis for developing 'cell transplant'-type vaccines in the future. Wed, 28 Dec 2022 13:04:09 EST //www.koonmotors.com/releases/2022/12/221228130409.htm //www.koonmotors.com/releases/2022/12/221226094519.htm Researchers report that they have developed a new experimental pipeline to combine bacterial therapy with current cancer drugs. Their study, which explores resistance to bacterial therapy at the molecular level, has achieved better treatment efficacy without additional toxicity in laboratory models. Mon, 26 Dec 2022 09:45:19 EST //www.koonmotors.com/releases/2022/12/221226094519.htm //www.koonmotors.com/releases/2022/12/221222101017.htm Pathogens such as SARS-CoV-2 and pneumococcus can cause severe pneumonia. If the airways then fill with fluid, the patient risks developing acute respiratory distress syndrome. Researchers have now discovered the molecular mechanisms that trigger fluid accumulation in the lungs. This also led them to discover a potential new therapy: A cystic fibrosis drug proved effective in their laboratory experiments, raising hope that this could be used to treat pneumonia regardless of the pathogen that caused it. Thu, 22 Dec 2022 10:10:17 EST //www.koonmotors.com/releases/2022/12/221222101017.htm //www.koonmotors.com/releases/2022/12/221222101008.htm Children exhale significantly fewer potentially infectious particles than adults -- at least this is true for the small respiratory droplets that are predominantly produced in the lungs. Thu, 22 Dec 2022 10:10:08 EST //www.koonmotors.com/releases/2022/12/221222101008.htm //www.koonmotors.com/releases/2022/12/221221121223.htm Researchers have genetically profiled nearly 200,000 cells from lungs, mapping their precise locations in tissue to discover an unexpected new immune niche in our airways Wed, 21 Dec 2022 12:12:23 EST //www.koonmotors.com/releases/2022/12/221221121223.htm //www.koonmotors.com/releases/2022/12/221206105915.htm Researchers have produced dark-field X-ray images of patients infected with the corona virus. In contrast to conventional X-ray images, dark-field images visualize the microstructure of the lung tissue, thereby providing additional information. Tue, 06 Dec 2022 10:59:15 EST //www.koonmotors.com/releases/2022/12/221206105915.htm //www.koonmotors.com/releases/2022/12/221205104257.htm A six-month study oncludes that the use of portable home air purifiers can improve some markers of cardiovascular health in people with chronic obstructive pulmonary disease, or COPD Mon, 05 Dec 2022 10:42:57 EST //www.koonmotors.com/releases/2022/12/221205104257.htm //www.koonmotors.com/releases/2022/12/221202112511.htm In a new study, researchers sought to determine the percentage of COVID-19 patients discharged from the hospital who had a type of fibrotic lung damage, known as interstitial lung disease, that requires ongoing follow-up care. These patients had varying degrees of COVID-19 severity at hospital admission. Fri, 02 Dec 2022 11:25:11 EST //www.koonmotors.com/releases/2022/12/221202112511.htm //www.koonmotors.com/releases/2022/12/221201203926.htm 大约80%的癌症患者患有significant muscle wasting, or loss of muscle tissue, and 30% of these patients die from this condition. New research in mice finds that the severity of muscle wasting is related to the type, size and location of the tumor. Thu, 01 Dec 2022 20:39:26 EST //www.koonmotors.com/releases/2022/12/221201203926.htm //www.koonmotors.com/releases/2022/11/221130114521.htm New research has uncovered mechanisms involved in the rapid, severe progression of fibrosis in the lung tissues of COVID-19 patients, a potentially fatal complication of the virus that damages and scars the lungs. Wed, 30 Nov 2022 11:45:21 EST //www.koonmotors.com/releases/2022/11/221130114521.htm //www.koonmotors.com/releases/2022/11/221129143827.htm While it may seem common knowledge that smoking is bad for your lungs, if and how ultrafine particles present in cigarette smoke impact the development and progression of lung cancer remains unclear. Working with animal models, researchers sought to find how airborne ultrafine particles in smoke can change a host's defense against lung cancer. Tue, 29 Nov 2022 14:38:27 EST //www.koonmotors.com/releases/2022/11/221129143827.htm //www.koonmotors.com/releases/2022/11/221129112633.htm New CT technology outperforms conventional CT in detecting subtle damage in the lungs of patients with persistent symptoms of COVID-19, according to a new study. The technology could lead the way to earlier treatment and better outcomes for the growing number of people with COVID-related lung damage, researchers said. Tue, 29 Nov 2022 11:26:33 EST //www.koonmotors.com/releases/2022/11/221129112633.htm //www.koonmotors.com/releases/2022/11/221122111426.htm Antibiotic resistant Pseudomonas bacteria were found to translocate from the gut to the lungs, where more life threatening infections could arise. Tue, 22 Nov 2022 11:14:26 EST //www.koonmotors.com/releases/2022/11/221122111426.htm //www.koonmotors.com/releases/2022/11/221121213544.htm Infectious diseases experts warn of the rising threat and apparent spread of disease-causing fungi outside their traditional hot spots. Fungal lung infections are commonly misdiagnosed, leading to delays in treatment and increase in antimicrobial resistance in the community. Mon, 21 Nov 2022 21:35:44 EST //www.koonmotors.com/releases/2022/11/221121213544.htm //www.koonmotors.com/releases/2022/11/221117102813.htm Inhalation therapy for asthma and other obstructive lung diseases often loses its effect following prolonged use. A research team has now shown an alternative signalling pathway through which the body's own cannabinoids cause the bronchial tubes to dilate. This gives rise to hope for alternative treatment options. Asthma is evidently also associated with a deficiency of these cannabinoids in the bronchial tubes, which could be one of the causes of the disease. Thu, 17 Nov 2022 10:28:13 EST //www.koonmotors.com/releases/2022/11/221117102813.htm //www.koonmotors.com/releases/2022/11/221116200021.htm Researchers have discovered that the three main kinds of soil fungi that cause lung infections have all expanded their ranges in recent decades. Reliance on outdated maps could be causing delayed or missed diagnoses. Wed, 16 Nov 2022 20:00:21 EST //www.koonmotors.com/releases/2022/11/221116200021.htm //www.koonmotors.com/releases/2022/11/221115113940.htm Airway inflammation and emphysema are more common in marijuana smokers than cigarette smokers, according to a new study. Researchers said the difference may be due to the way that marijuana is smoked and the fact that marijuana smoke enters the lungs unfiltered. Tue, 15 Nov 2022 11:39:40 EST //www.koonmotors.com/releases/2022/11/221115113940.htm //www.koonmotors.com/releases/2022/11/221108120419.htm Scientists investigating the mechanics of the early stages of lung cancer have identified a new potential treatment, which could also aid early detection of the disease. Levels of a key protein -- called TLR2 -- in tumors was found to predict a patient's survival after being diagnosed with lung cancer, a study shows. A drug compound that activates TLR2 was tested in mice and was found to reduce tumor growth in the early stages of the disease. Tue, 08 Nov 2022 12:04:19 EST //www.koonmotors.com/releases/2022/11/221108120419.htm //www.koonmotors.com/releases/2022/11/221103104945.htm New research addresses a long-standing question in pulmonary medicine about whether modern ventilators overstretch lung tissue. Thu, 03 Nov 2022 10:49:45 EDT //www.koonmotors.com/releases/2022/11/221103104945.htm //www.koonmotors.com/releases/2022/11/221102110525.htm Researchers have created an advanced model that can detect lung damage in long-COVID patients using a simple chest X-ray. The model takes data points from 3D CT lung scans and transfers them to be diagnosed by 2D chest X-ray equipment, which is more commonly available and less costly. Wed, 02 Nov 2022 11:05:25 EDT //www.koonmotors.com/releases/2022/11/221102110525.htm //www.koonmotors.com/releases/2022/10/221026103136.htm Preventing severe lung infections in mechanically ventilated intensive care patients by applying topical antibiotics to the upper digestive tract results in a clinically meaningful improvement in survival, new research shows. Wed, 26 Oct 2022 10:31:36 EDT //www.koonmotors.com/releases/2022/10/221026103136.htm //www.koonmotors.com/releases/2022/10/221025090509.htm A new study has revealed significant racial disparities in how quickly minorities with the most common form of lung cancer receive potentially lifesaving radiation therapy compared with their white counterparts. Tue, 25 Oct 2022 09:05:09 EDT //www.koonmotors.com/releases/2022/10/221025090509.htm //www.koonmotors.com/releases/2022/10/221017142449.htm People with a disease characterized by lung scarring that has no obvious cause are more likely to die if they live in areas with higher levels of air pollution composed of chemicals associated with industrial sources and vehicular traffic, according to new research. Mon, 17 Oct 2022 14:24:49 EDT //www.koonmotors.com/releases/2022/10/221017142449.htm //www.koonmotors.com/releases/2022/10/221010115209.htm Military personnel who were deployed in Afghanistan and Iraq may have been exposed to significant amounts of dust and other respiratory hazards, leading to persistent respiratory symptoms and diseases like asthma and bronchiolitis. Mon, 10 Oct 2022 11:52:09 EDT //www.koonmotors.com/releases/2022/10/221010115209.htm //www.koonmotors.com/releases/2022/10/221004104939.htm In one of the largest single-center COVID-19 cohort studies to date, researchers have identified a key driver of COVID-19 disease severity. The findings suggest that lung damage is linked to the loss of immune cells called macrophages that normally reside in the lung and organize tissue repair, followed by an influx of new macrophages from the blood into the lung that cause inflammation. Tue, 04 Oct 2022 10:49:39 EDT //www.koonmotors.com/releases/2022/10/221004104939.htm //www.koonmotors.com/releases/2022/09/220927102351.htm Researchers have analyzed the manifestations of COVID-19 in the lungs and colon and pinpointed the differences at a molecular level. Their findings form the basis for the identification of novel biomarkers and the development of new treatment strategies. Tue, 27 Sep 2022 10:23:51 EDT //www.koonmotors.com/releases/2022/09/220927102351.htm