//www.koonmotors.com/news/health_medicine/hormone_disorders/ Read the latest research on endocrinology. Learn about hormone disorders, new hormone treatment options, hormone therapy and more. en-us Wed, 06 Sep 2023 14:46:00 EDT Wed, 06 Sep 2023 14:46:00 EDT 60 //www.koonmotors.com/images/scidaily-logo-rss.png//www.koonmotors.com/news/health_medicine/hormone_disorders/ For more science news, visit ScienceDaily. //www.koonmotors.com/releases/2023/08/230821114358.htm Anti-estrogenic therapies can suppress the growth of cancer that does not express estrogen receptors; when combined with immune checkpoint inhibitor therapies, they halt tumor progression in mice models. Mon, 21 Aug 2023 11:43:58 EDT //www.koonmotors.com/releases/2023/08/230821114358.htm //www.koonmotors.com/releases/2023/07/230721113111.htm Around one third of people with heart disease suffer from sleep problems. A team now shows that heart diseases affect the production of the sleep hormone melatonin in the pineal gland. The link between the two organs is a ganglion in the neck region. The study demonstrates a previously unknown role of ganglia and points to possible treatments. Fri, 21 Jul 2023 11:31:11 EDT //www.koonmotors.com/releases/2023/07/230721113111.htm //www.koonmotors.com/releases/2023/07/230707111648.htm A new study suggests that birth-control pills negatively impact women's stress response. Fri, 07 Jul 2023 11:16:48 EDT //www.koonmotors.com/releases/2023/07/230707111648.htm //www.koonmotors.com/releases/2023/06/230621164740.htm Early warning signs of diseases caused by dysfunctional levels of stress hormones could be spotted more easily thanks to a new wearable device developed by researchers. Wed, 21 Jun 2023 16:47:40 EDT //www.koonmotors.com/releases/2023/06/230621164740.htm //www.koonmotors.com/releases/2023/06/230615183242.htm Exposure to dioxins can negatively impact thyroid function, according to a study presented Thursday at ENDO 2023, the Endocrine Society's annual meeting in Chicago, Ill. Thu, 15 Jun 2023 18:32:42 EDT //www.koonmotors.com/releases/2023/06/230615183242.htm //www.koonmotors.com/releases/2023/03/230322190838.htm Researchers have developed a handheld sensor that tests perspiration for cortisol and provides results in eight minutes, a key advance in monitoring a hormone whose levels are a marker for many illnesses including various cancers. Wed, 22 Mar 2023 19:08:38 EDT //www.koonmotors.com/releases/2023/03/230322190838.htm //www.koonmotors.com/releases/2023/01/230116112537.htm Doctors have used a new type of CT scan to light up tiny nodules in a hormone gland and cure high blood pressure by their removal. The nodules are discovered in one-in-twenty people with high blood pressure. 星期一,2023年1月16日11:25:37 EST //www.koonmotors.com/releases/2023/01/230116112537.htm //www.koonmotors.com/releases/2022/12/221206204809.htm Researchers identified an oral compound that influences components of the parathyroid hormone signaling pathway to increase bone formation and bone mass in mice. Tue, 06 Dec 2022 20:48:09 EST //www.koonmotors.com/releases/2022/12/221206204809.htm //www.koonmotors.com/releases/2022/11/221121130617.htm A team coaxed stem cells to take on the characteristics and functions of a human adrenal gland, progress that could lead to new therapies for adrenal insufficiencies and a deeper understanding of the genetics of such disorders. Mon, 21 Nov 2022 13:06:17 EST //www.koonmotors.com/releases/2022/11/221121130617.htm //www.koonmotors.com/releases/2022/11/221108082617.htm Researchers have discovered the vital role of a hormone, that develops in men during puberty, in providing an early prediction of whether they could develop certain diseases in later life. Tue, 08 Nov 2022 08:26:17 EST //www.koonmotors.com/releases/2022/11/221108082617.htm //www.koonmotors.com/releases/2022/11/221107192302.htm A new drug called Baxdrostat has been shown to significantly reduce high blood pressure (hypertension) in patients who may not respond to current treatments for the condition, according to results from a phase II trial. 妈,07年2022年11月19日:23:02 EST //www.koonmotors.com/releases/2022/11/221107192302.htm //www.koonmotors.com/releases/2022/11/221102110517.htm Diabetes, which affects millions of people worldwide, develops when the body either generates insufficient amounts of the hormone insulin -- a hormone that maintains healthy blood sugar -- or when the body cannot effectively use the insulin it produces. When the number of beta cells is too low or they aren't functioning properly, there isn't enough insulin getting released. Beta cells communicate with each other to secrete insulin in a coordinated manner. Scientists now show that the gene Wnt4 in beta cells enables them to sense glucose and release the hormone insulin that enables other cells in the body to store glucose. These insights could help to create replacement beta cells for diabetes therapy in the future. Wed, 02 Nov 2022 11:05:17 EDT //www.koonmotors.com/releases/2022/11/221102110517.htm //www.koonmotors.com/releases/2022/10/221027123944.htm Patient-derived parathyroid organoids (PTOs) could pave the way for future physiology studies and drug-screening applications, as shown in a new study. Thu, 27 Oct 2022 12:39:44 EDT //www.koonmotors.com/releases/2022/10/221027123944.htm //www.koonmotors.com/releases/2022/10/221020140606.htm Scientists have developed a new way of looking at sex-biased diseases that is rooted in evolutionary biology. Thu, 20 Oct 2022 14:06:06 EDT //www.koonmotors.com/releases/2022/10/221020140606.htm //www.koonmotors.com/releases/2022/09/220912132329.htm The HSD3B1 gene could hold clues for predicting and treating endometrial cancer, according to a novel finding. Researchers found a certain HSD3B1 genotype was more common in women with type 2 endometrial cancer. Those patients show lower survival rates than those diagnosed with type 1 endometrial cancer, likely driven by the fact that type 2 patient cells are less hormone-dependent. Mon, 12 Sep 2022 13:23:29 EDT //www.koonmotors.com/releases/2022/09/220912132329.htm //www.koonmotors.com/releases/2022/09/220901135934.htm Overweight increases the risk of an imbalance in sugar metabolism and even of diabetes. A research group has now shown the opposite is true as well: deficits in the body's insulin production contribute to overweight. Thu, 01 Sep 2022 13:59:34 EDT //www.koonmotors.com/releases/2022/09/220901135934.htm //www.koonmotors.com/releases/2022/08/220824152312.htm A new scientific paper and other recent evidence offer important reassurances about the risk of breast cancer from hormone therapy to treat menopause symptoms, two menopause experts say. Wed, 24 Aug 2022 15:23:12 EDT //www.koonmotors.com/releases/2022/08/220824152312.htm //www.koonmotors.com/releases/2022/08/220818175207.htm In single pollutant models and within a 20-year period, 10 out of 29 reviewed pesticides were associated with thyroid cancer, including several of the most widely used ones in the U.S. These included paraquat dichloride, glyphosate and oxyfluorfen. Thu, 18 Aug 2022 17:52:07 EDT //www.koonmotors.com/releases/2022/08/220818175207.htm //www.koonmotors.com/releases/2022/07/220713114641.htm Researchers have developed a noninvasive method to identify a potential cause of hypertension with a drastic reduction in radiation exposure, a new study shows. The fluorine-based reagent detects whether the hormone aldosterone is being produced abnormally, which is a possible sign of an adrenal adenoma, a tumor that can cause hypertension and can be removed surgically. Wed, 13 Jul 2022 11:46:41 EDT //www.koonmotors.com/releases/2022/07/220713114641.htm //www.koonmotors.com/releases/2022/07/220706165418.htm Older people with hypothyroidism, also called underactive thyroid, may be at increased risk of developing dementia, according to a new study. The risk of developing dementia was even higher for people whose thyroid condition required thyroid hormone replacement medication. Wed, 06 Jul 2022 16:54:18 EDT //www.koonmotors.com/releases/2022/07/220706165418.htm //www.koonmotors.com/releases/2022/06/220630083255.htm Even before carbohydrates reach the bloodstream, the very sight and smell of a meal trigger the release of insulin. For the first time, researchers have shown that this insulin release depends on a short-term inflammatory response that takes place in these circumstances. In overweight individuals, however, this inflammatory response is so excessive that it can impair insulin secretion. Thu, 30 Jun 2022 08:32:55 EDT //www.koonmotors.com/releases/2022/06/220630083255.htm //www.koonmotors.com/releases/2022/06/220624092436.htm 雌性激素雌二醇抑制被发现psoriasis in mice by regulating neutrophil and macrophage cells. The conditional knockout mice without the natural ovarian hormones estradiol showed symptoms of severe skin inflammation. Fri, 24 Jun 2022 09:24:36 EDT //www.koonmotors.com/releases/2022/06/220624092436.htm //www.koonmotors.com/releases/2022/06/220622101340.htm In a leap forward for diabetes research, researchers reveal that the feel-good hormone, dopamine, regulates insulin secretion through a heteromeric complex of receptors, thereby providing new targets for antidiabetic medication and therapy. The study is the first to elucidate the mechanism behind dopamine's down-regulation of insulin secretion. Wed, 22 Jun 2022 10:13:40 EDT //www.koonmotors.com/releases/2022/06/220622101340.htm //www.koonmotors.com/releases/2022/06/220614122713.htm 绝经后的雌激素缺乏是thought to impair women's ability to use fat as an energy source. A study shows that menopausal state or blood estrogen levels do not clearly determine the rate middle-aged women are able to use fat at rest or during exercise. Higher fat utilization did not indicate better glucose tolerance. Tue, 14 Jun 2022 12:27:13 EDT //www.koonmotors.com/releases/2022/06/220614122713.htm //www.koonmotors.com/releases/2022/05/220520132850.htm Two recent discoveries may help lead to new ways to treat patients with Allan-Herndon-Dudley syndrome (AHDS), a brain development disorder that causes severe intellectual disability and problems with movement. Fri, 20 May 2022 13:28:50 EDT //www.koonmotors.com/releases/2022/05/220520132850.htm //www.koonmotors.com/releases/2022/05/220515113212.htm Levels of bad cholesterol rise during menopause, and 10% of this increase is likely due to shifts in sex hormones. Women usually undergo menopause at the age of 48 to 52 years, leading to a decline in estrogen and increase in follicle-stimulating hormone (FSH). Menopause is thought to predispose women to heart disease since it typically develops 10 years later than in men, and risk rises after menopause. Sun, 15 May 2022 11:32:12 EDT //www.koonmotors.com/releases/2022/05/220515113212.htm //www.koonmotors.com/releases/2022/05/220510102841.htm Female rats exposed to a scream sound may have diminished ovarian reserve and reduced fertility, according to a small animal study. Tue, 10 May 2022 10:28:41 EDT //www.koonmotors.com/releases/2022/05/220510102841.htm //www.koonmotors.com/releases/2022/04/220428125446.htm Researchers have shown that exposure to endocrine disruptors during pregnancy can lead to medium and long-term health problems for both the mother and the fetus. They conducted an exhaustive review of the literature on more than a dozen of the most common endocrine disruptors (EDs), as well as several whose effects are less well-known. Thu, 28 Apr 2022 12:54:46 EDT //www.koonmotors.com/releases/2022/04/220428125446.htm //www.koonmotors.com/releases/2022/04/220421094145.htm A new statement describes the importance of extracellular vesicles as a new research target for understanding the causes of certain endocrine disorders such as cancer and diabetes and discovering new treatments for these disorders. Thu, 21 Apr 2022 09:41:45 EDT //www.koonmotors.com/releases/2022/04/220421094145.htm //www.koonmotors.com/releases/2022/04/220419092324.htm Scientists show that endocrine stem cells in the pancreas disappear after birth, and detail the genetic identity of the different types of pancreatic hormone-producing cells. Tue, 19 Apr 2022 09:23:24 EDT //www.koonmotors.com/releases/2022/04/220419092324.htm //www.koonmotors.com/releases/2022/03/220307113126.htm A new study reports that the loss of sex steroid hormones produced by the enzyme 3-hydroxyl-steroid dehydrogenase, or 3-HSD, causes the condition, but it can be treated with nicotinamide mononucleotide, or NMN, which is a non-steroid agent. The research team's key interest in 3-HSD activity lies in its circadian rhythm, responsible for a number of oscillating physiological behaviors such as sleep, menstrual cycles, and hormone secretion. Mon, 07 Mar 2022 11:31:26 EST //www.koonmotors.com/releases/2022/03/220307113126.htm //www.koonmotors.com/releases/2022/02/220224112635.htm A research team confirmed that interference with the action of arginine vasopressin and corticotrophin-releasing hormone inhibits stress responses in rats during moderate-intensity exercise. Their findings suggest that these factors cooperatively regulate adrenocorticotropic hormone secretion. Thu, 24 Feb 2022 11:26:35 EST //www.koonmotors.com/releases/2022/02/220224112635.htm //www.koonmotors.com/releases/2022/02/220218110716.htm Results from an international, randomized, double-blind, placebo-controlled, phase 3 clinical trial indicate that adding the androgen-receptor inhibitor darolutamide to androgen-deprivation therapy and chemotherapy prolongs the survival of men with metastatic, hormone-sensitive prostate cancer. Fri, 18 Feb 2022 11:07:16 EST //www.koonmotors.com/releases/2022/02/220218110716.htm //www.koonmotors.com/releases/2022/02/220208085006.htm Toxic goiter affects the brain more than was previously known, a new study shows, and involves volume changes occurring in central parts of the brain. These findings are described as a key advance for a vulnerable group of patients. Tue, 08 Feb 2022 08:50:06 EST //www.koonmotors.com/releases/2022/02/220208085006.htm //www.koonmotors.com/releases/2022/01/220112094017.htm Exposure to phthalates -- a group of chemicals found in everything from plastics to personal care products to electronics -- may disrupt an important hormone needed to sustain a healthy pregnancy, according to a new study. The study has examined the impact that phthalates, added to plastics to increase flexibility, have on the placental corticotropin releasing hormone (pCRH) that is produced by the placenta and increases throughout the course of pregnancy. Wed, 12 Jan 2022 09:40:17 EST //www.koonmotors.com/releases/2022/01/220112094017.htm //www.koonmotors.com/releases/2022/01/220106100407.htm Thyroid hormone levels during pregnancy may predict preschool boys' emotional and behavioral problems, according to a new study. Thu, 06 Jan 2022 10:04:07 EST //www.koonmotors.com/releases/2022/01/220106100407.htm //www.koonmotors.com/releases/2022/01/220104095608.htm Scientists are calling for changes to healthcare policy following research which has shown for the first time the scale of the impact of a condition associated with benign tumors that can lead to type 2 diabetes and high blood pressure. Up to 10 per cent of adults have a benign tumor, or lump, known as an 'adrenal incidentaloma' in their adrenals -- glands situated on top of the kidneys which produce a variety of hormones. Tue, 04 Jan 2022 09:56:08 EST //www.koonmotors.com/releases/2022/01/220104095608.htm //www.koonmotors.com/releases/2021/12/211210125741.htm The use of certain personal care products during pregnancy may impact maternal hormone levels, according to a new study. Fri, 10 Dec 2021 12:57:41 EST //www.koonmotors.com/releases/2021/12/211210125741.htm //www.koonmotors.com/releases/2021/12/211210103124.htm A study measured arterial stiffness in women from wide age range. Increased stiffness is an independent risk factor for cardiovascular disease. Age was a strong determinant of arterial stiffness. Indicative of the role of hormones, menstrual cycle phase, contraceptive pill phase and menopausal state were also associated with arterial stiffness. Fri, 10 Dec 2021 10:31:24 EST //www.koonmotors.com/releases/2021/12/211210103124.htm //www.koonmotors.com/releases/2021/12/211208123349.htm A newly discovered hormone named fabkin helps regulate metabolism and may play an important role in the development of both type 1 and type 2 diabetes, according to new research. Wed, 08 Dec 2021 12:33:49 EST //www.koonmotors.com/releases/2021/12/211208123349.htm //www.koonmotors.com/releases/2021/11/211109095351.htm Leptin, a molecule produced by fat cells, appears to cancel out the effects of the estrogen-blocking therapy tamoxifen, a drug commonly used to treat and prevent breast cancers, suggests a new study. Tue, 09 Nov 2021 09:53:51 EST //www.koonmotors.com/releases/2021/11/211109095351.htm //www.koonmotors.com/releases/2021/11/211104140355.htm The drop in estrogen levels that occurs with menopause brings declines in the volumes of 'gray matter,' the cellular matter of the brain, in key brain regions that are also affected in Alzheimer's disease. But a new study suggests that greater cumulative exposure to estrogen in life, for example from having had more children or from having taken menopause hormone therapy, may counter this brain-shrinking effect. Thu, 04 Nov 2021 14:03:55 EDT //www.koonmotors.com/releases/2021/11/211104140355.htm //www.koonmotors.com/releases/2021/10/211014131224.htm 分子的原因——一种特殊的食物dependent Cushing's Syndrome, a rare disease of the adrenal glands, are finally revealed. Thu, 14 Oct 2021 13:12:24 EDT //www.koonmotors.com/releases/2021/10/211014131224.htm //www.koonmotors.com/releases/2021/10/211007145906.htm Common gut bacteria can become 'hormone factories' - fuelling prostate cancer and making it resistant to treatment, a new study shows. Scientists revealed how gut bacteria contribute to the progression of advanced prostate cancers and their resistance to hormone therapy -- by providing an alternative source of growth-promoting androgens, or male hormones. The findings, once further validated in the clinic, could provide new opportunities for the treatment of prostate cancer through manipulation of the microbiome. Thu, 07 Oct 2021 14:59:06 EDT //www.koonmotors.com/releases/2021/10/211007145906.htm //www.koonmotors.com/releases/2021/10/211001082614.htm Daily release of hormones depends on the coordinated activity of clocks in two parts of the brain, a finding that could have implications for human diseases. Fri, 01 Oct 2021 08:26:14 EDT //www.koonmotors.com/releases/2021/10/211001082614.htm //www.koonmotors.com/releases/2021/09/210927132101.htm Researchers suggest that advances in breast cancer prevention research have resulted in new and innovative opportunities to modify breast cancer risk and potentially reduce breast cancer incidence and mortality. Mon, 27 Sep 2021 13:21:01 EDT //www.koonmotors.com/releases/2021/09/210927132101.htm //www.koonmotors.com/releases/2021/09/210913135723.htm In a study of more than 400 adults with normal blood pressure, those who had high levels of stress hormones detected in their urine were more likely to develop high blood pressure over the next 6-7 years. Higher levels of the stress hormone cortisol were also linked to an increased risk of cardiovascular events, including heart attack and stroke. Mon, 13 Sep 2021 13:57:23 EDT //www.koonmotors.com/releases/2021/09/210913135723.htm //www.koonmotors.com/releases/2021/09/210913135616.htm Researchers have demonstrated that an experimental device can improve blood sugar control in patients who developed diabetes after their pancreas was removed to treat their hyperinsulinism, a genetic disease in which the pancreas produces too much insulin. Using a combination of continuous glucose monitoring, two hormone pumps, and an algorithm, the device, known as the bihormonal bionic pancreas (BHBP), helped HI patients with diabetes maintain stable glucose levels over the study period. Mon, 13 Sep 2021 13:56:16 EDT //www.koonmotors.com/releases/2021/09/210913135616.htm //www.koonmotors.com/releases/2021/08/210812123047.htm An international study has found a unique pair of gene variants that causes sudden onset high blood pressure in pregnant women. Thu, 12 Aug 2021 12:30:47 EDT //www.koonmotors.com/releases/2021/08/210812123047.htm //www.koonmotors.com/releases/2021/08/210810104650.htm Hormones released after a brain injury contribute to movement problems on the left and right sides of the body, scientists from Uppsala University and elsewhere can now show in a new study in rats. The results also suggest that hormone-blocking treatments may help counteract these effects, a finding that has implications for treating people with traumatic brain injuries or stroke. Tue, 10 Aug 2021 10:46:50 EDT //www.koonmotors.com/releases/2021/08/210810104650.htm //www.koonmotors.com/releases/2021/07/210728150337.htm In an attempt to find out why the long-term outcomes are poorer for patients with lobular breast cancer -- which affects some 40,000 women a year -- researchers began looking at the role of the protein MDC1 in tumor cells. Wed, 28 Jul 2021 15:03:37 EDT //www.koonmotors.com/releases/2021/07/210728150337.htm //www.koonmotors.com/releases/2021/07/210712092238.htm When it comes to post-menopausal hormone therapy, the type, route and duration all play a role in reducing the risk of neurodegenerative diseases. Mon, 12 Jul 2021 09:22:38 EDT //www.koonmotors.com/releases/2021/07/210712092238.htm //www.koonmotors.com/releases/2021/07/210709104241.htm A research team performs machine learning-powered photoacoustic/ultrasound imaging for thyroid cancer classification. Fri, 09 Jul 2021 10:42:41 EDT //www.koonmotors.com/releases/2021/07/210709104241.htm //www.koonmotors.com/releases/2021/07/210702154327.htm Maternal exposure to air pollution during pregnancy has often been linked to adverse effects on the health of the newborn. However, there are very few studies on the subject. A study has just concluded that the stages most sensitive to air pollution are the early and late months of pregnancy. Fri, 02 Jul 2021 15:43:27 EDT //www.koonmotors.com/releases/2021/07/210702154327.htm //www.koonmotors.com/releases/2021/07/210701112610.htm Scientists have found an essential factor from the extracellular matrix that regulates functionality of the breast tissue for instance during pregnancy. Thu, 01 Jul 2021 11:26:10 EDT //www.koonmotors.com/releases/2021/07/210701112610.htm //www.koonmotors.com/releases/2021/06/210615132136.htm Stem cell biologist have discovered that the pituitary gland in mice ages as the result of an age-related form of chronic inflammation. It may be possible to slow down this process or even partially repair it. Tue, 15 Jun 2021 13:21:36 EDT //www.koonmotors.com/releases/2021/06/210615132136.htm //www.koonmotors.com/releases/2021/05/210512142846.htm Researchers have investigated the role that hormones play in male and female inflammatory responses. In a new study, he found that testosterone may protect against stomach inflammation. Wed, 12 May 2021 14:28:46 EDT //www.koonmotors.com/releases/2021/05/210512142846.htm //www.koonmotors.com/releases/2021/03/210331143023.htm Researchers have identified the biological mechanism of how chronic stress leads to hair loss. They found that the stress hormone corticosterone causes hair follicle stem cells to stay in an extended resting phase, without regenerating tissue. The stress signal was first received by dermal cells surrounding the hair follicle, preventing them from releasing Gas6, a molecule that activates stem cells. When researchers added back Gas6, stem cells could regenerate hair even under stress. Wed, 31 Mar 2021 14:30:23 EDT //www.koonmotors.com/releases/2021/03/210331143023.htm //www.koonmotors.com/releases/2021/03/210309091308.htm Illegal use of anabolic steroids not only has dangerous side effects during use but also can harm of men's testicular function years after they stop abusing steroids, according to a new study. Tue, 09 Mar 2021 09:13:08 EST //www.koonmotors.com/releases/2021/03/210309091308.htm //www.koonmotors.com/releases/2021/03/210301171025.htm Blocking cell receptors for glucagon, the counter-hormone to insulin, cured mouse models of diabetes by converting glucagon-producing cells into insulin producers instead, a team reports in a new study. The findings could offer a new way to treat both Type 1 and Type 2 diabetes in people. Mon, 01 Mar 2021 17:10:25 EST //www.koonmotors.com/releases/2021/03/210301171025.htm