//www.koonmotors.com/news/health_medicine/colon_cancer/ Information about cancer prevention, screening, symptoms and treatments. Read about stages of colon cancer and cancer prognosis. Explore the latest research on colon cancer. en-us Fri, 08 Sep 2023 22:45:45 EDT Fri, 08 Sep 2023 22:45:45 EDT 60 //www.koonmotors.com/images/scidaily-logo-rss.png//www.koonmotors.com/news/health_medicine/colon_cancer/ For more science news, visit ScienceDaily. //www.koonmotors.com/releases/2023/08/230821114358.htm Anti-estrogenic therapies can suppress the growth of cancer that does not express estrogen receptors; when combined with immune checkpoint inhibitor therapies, they halt tumor progression in mice models. Mon, 21 Aug 2023 11:43:58 EDT //www.koonmotors.com/releases/2023/08/230821114358.htm //www.koonmotors.com/releases/2023/06/230628130408.htm In an exciting new study adding to the global pool of knowledge about the roots of human cancers, researchers are establishing a clear link between different types of cancers and their embryonic origins. They also identify new concepts that can be considered in future drug discovery projects and used in standard chemotherapeutics in the clinic. Wed, 28 Jun 2023 13:04:08 EDT //www.koonmotors.com/releases/2023/06/230628130408.htm //www.koonmotors.com/releases/2023/05/230531150141.htm A new study has linked certain types of gut bacteria to the development of precancerous colon polyps. Wed, 31 May 2023 15:01:41 EDT //www.koonmotors.com/releases/2023/05/230531150141.htm //www.koonmotors.com/releases/2023/03/230316140939.htm Researchers outline the complexities of young-onset colorectal cancer and the research needed to map out a path toward understanding it. Thu, 16 Mar 2023 14:09:39 EDT //www.koonmotors.com/releases/2023/03/230316140939.htm //www.koonmotors.com/releases/2023/01/230117110522.htm Researchers studied human colon cancer tissue samples and animal models and found that exposure to salmonella was linked with colon cancers that developed earlier and grew larger. 星期二,2023年1月17日11:05:22 EST //www.koonmotors.com/releases/2023/01/230117110522.htm //www.koonmotors.com/releases/2022/12/221201203926.htm About 80% of people with cancer suffer from significant muscle wasting, or loss of muscle tissue, and 30% of these patients die from this condition. New research in mice finds that the severity of muscle wasting is related to the type, size and location of the tumor. Thu, 01 Dec 2022 20:39:26 EST //www.koonmotors.com/releases/2022/12/221201203926.htm //www.koonmotors.com/releases/2022/11/221129112643.htm A scientific study exploring the appropriate interval for colorectal cancer screening via non-invasive multi-target stool DNA testing for individuals with average risk for the disease reported finding no colorectal cancers three years after an initial negative multi-target stool DNA test. These results suggest that at least a three-year interval between screenings using this method is clinically appropriate. Tue, 29 Nov 2022 11:26:43 EST //www.koonmotors.com/releases/2022/11/221129112643.htm //www.koonmotors.com/releases/2022/11/221125132150.htm Researchers have designed cancer-fighting nanoparticles that co-deliver a chemotherapy drug and a novel immunotherapy, according to a new study. Fri, 25 Nov 2022 13:21:50 EST //www.koonmotors.com/releases/2022/11/221125132150.htm //www.koonmotors.com/releases/2022/11/221118130021.htm A dietary change could be a key to enhancing colon cancer treatment, a new study finds. Researchers found in cells and in mice that a low-protein diet blocked the nutrient signaling pathway that fires up a master regulator of cancer growth. Fri, 18 Nov 2022 13:00:21 EST //www.koonmotors.com/releases/2022/11/221118130021.htm //www.koonmotors.com/releases/2022/11/221117135550.htm 研究人员说covered a new mechanism that explains why only some of the cells in a colon tumor respond to chemotherapy. The research team was able to establish that tumor cells dying off during chemotherapy communicate one last time with neighboring tumor cells to give them instructions on how to resist the therapy. The dying cells re-program the signalling cascades in the neighboring tumor cells in such a way that these are no longer vulnerable to chemotherapy. By doing so, the dying cells literally ensure that the tumor survives. Thu, 17 Nov 2022 13:55:50 EST //www.koonmotors.com/releases/2022/11/221117135550.htm //www.koonmotors.com/releases/2022/11/221109151943.htm 研究报告发现的人口of residual tumor cells responsible for the recurrence of colorectal cancer in other organs after removal of the primary tumor. The study shows that early immunotherapy, before surgery, can eliminate these cells before they have started to develop a metastasis, and thus prevent relapse of the disease. The work paves the way for the development of new therapeutic approaches and diagnostic tools to slow down the progression of the disease and improve its prognosis. Wed, 09 Nov 2022 15:19:43 EST //www.koonmotors.com/releases/2022/11/221109151943.htm //www.koonmotors.com/releases/2022/10/221027154154.htm Medical researchers have developed new chemical compounds that show promise in a potential anticancer therapy to treat aggressive tumors. Thu, 27 Oct 2022 15:41:54 EDT //www.koonmotors.com/releases/2022/10/221027154154.htm //www.koonmotors.com/releases/2022/10/221027093324.htm Colorectal cancer is one of the most common cancers. Its treatment is mainly based on chemotherapy. However, over time, chemotherapy induces resistance in the majority of patients, who end up being unresponsive to the drugs. As a result, the five-year survival rate for those affected is still low. After succeeding in reproducing this resistance in the laboratory, a team has found a way to overcome it. Thu, 27 Oct 2022 09:33:24 EDT //www.koonmotors.com/releases/2022/10/221027093324.htm //www.koonmotors.com/releases/2022/10/221017081911.htm Researchers have identified a new gene that is essential to colon cancer growth and found that inflammation in the external environment around the tumor can contribute to the growth of tumor cells. Mon, 17 Oct 2022 08:19:11 EDT //www.koonmotors.com/releases/2022/10/221017081911.htm //www.koonmotors.com/releases/2022/09/220908120506.htm Physical activity may be associated with improved outcomes for patients undergoing postoperative treatment for Stage III colon cancer, a new study suggests. Thu, 08 Sep 2022 12:05:06 EDT //www.koonmotors.com/releases/2022/09/220908120506.htm //www.koonmotors.com/releases/2022/08/220810161028.htm In a new study, researchers define how the circadian clock influences cell growth, metabolism and tumor progression. Their research also reveals how disruption of the circadian clock impacts genome stability and mutations that can further drive critical tumor promoting pathways in the intestine. Wed, 10 Aug 2022 16:10:28 EDT //www.koonmotors.com/releases/2022/08/220810161028.htm //www.koonmotors.com/releases/2022/08/220804102542.htm Researchers have combined optical coherence tomography (OCT) and machine learning to develop a colorectal cancer imaging tool that may one day improve the traditional endoscopy currently used by doctors. Thu, 04 Aug 2022 10:25:42 EDT //www.koonmotors.com/releases/2022/08/220804102542.htm //www.koonmotors.com/releases/2022/08/220802121735.htm Colorectal tumors are a common adverse effect of chronic inflammation of the intestine. In a new study, researchers demonstrate that mice models with dendritic cell immunoreceptor (DCIR) protein deficiency are resistant to colonic tumors induced by dextran sodium sulfate and azoxymethane. Further, they identify an antibody that reduces colitis severity and colonic tumor growth, highlighting the potential of DCIR as a therapeutic target. Tue, 02 Aug 2022 12:17:35 EDT //www.koonmotors.com/releases/2022/08/220802121735.htm //www.koonmotors.com/releases/2022/07/220725105652.htm Researchers designed a silicon-based agent that successfully generated hydrogen continuously in the mouse gastrointestinal tract in an ulcerative colitis (UC) model. The hydrogen served as an antioxidant that could eliminate the reactive oxygen species shown to induce the chronic inflammation responsible for the damage and symptoms caused by UC. Mice given the agent had reduced hemorrhage, inflammation, and hyperexcitability in the brain area associated with visceral pain and discomfort. These results may help with the development of a novel treatment for UC. Mon, 25 Jul 2022 10:56:52 EDT //www.koonmotors.com/releases/2022/07/220725105652.htm //www.koonmotors.com/releases/2022/07/220722184822.htm Colorectal tumors are swarming with white blood cells, but whether these cells help or hinder the cancer is hotly debated. While some studies have shown that white blood cells heroically restrict tumor growth and combat colorectal cancer, equally compelling evidence casts the white blood cells as malignant co-conspirators -- bolstering the tumor and helping it spread. Fri, 22 Jul 2022 18:48:22 EDT //www.koonmotors.com/releases/2022/07/220722184822.htm //www.koonmotors.com/releases/2022/07/220714091121.htm Data suggest that Clostridioides difficile, or C. diff, a bacterial species well known for causing serious diarrheal infections, may also drive colorectal cancer. Thu, 14 Jul 2022 09:11:21 EDT //www.koonmotors.com/releases/2022/07/220714091121.htm //www.koonmotors.com/releases/2022/06/220627124937.htm New research builds the case that a Western-style diet -- rich in red and processed meat, sugar and refined grains/carbohydrates -- is tied to higher risk of colorectal cancer through the intestinal microbiota. Mon, 27 Jun 2022 12:49:37 EDT //www.koonmotors.com/releases/2022/06/220627124937.htm //www.koonmotors.com/releases/2022/06/220623091201.htm New research in mice has paved the way for a Phase I clinical trial and has the potential to transform vaccines against HIV and malaria. Thu, 23 Jun 2022 09:12:01 EDT //www.koonmotors.com/releases/2022/06/220623091201.htm //www.koonmotors.com/releases/2022/06/220621184450.htm 一个新的联合治疗战胜癌症的可能啊ne day consist of a plant virus and an antibody that activates the immune system's 'natural killer' cells, shows a new study. In mouse models of colon cancer, the combination therapy eliminated all tumors and prevented their recurrence, which in turn resulted in 100% survival. The therapy also increased survival in mouse models of melanoma. Tue, 21 Jun 2022 18:44:50 EDT //www.koonmotors.com/releases/2022/06/220621184450.htm //www.koonmotors.com/releases/2022/06/220614141540.htm 研究人员说covered a possible new approach in treating solid tumors through the creation of a novel nanoparticle. Tue, 14 Jun 2022 14:15:40 EDT //www.koonmotors.com/releases/2022/06/220614141540.htm //www.koonmotors.com/releases/2022/06/220604082951.htm A multi-institutional, international study found that testing for ctDNA after surgery and directing chemotherapy to ctDNA-positive patients reduced the use of chemotherapy overall without compromising recurrence-free survival. Sat, 04 Jun 2022 08:29:51 EDT //www.koonmotors.com/releases/2022/06/220604082951.htm //www.koonmotors.com/releases/2022/05/220505143805.htm A new study reports a 50 to 60 percent lower risk of colorectal cancer (CRC) among women who started endoscopy screening at age 45 compared to those who had not undergone screening at all. Thu, 05 May 2022 14:38:05 EDT //www.koonmotors.com/releases/2022/05/220505143805.htm //www.koonmotors.com/releases/2022/04/220427115716.htm Beta-hydroxybutyrate, an alternative-energy molecule produced by the body in response to starvation or low-carb diets, strongly suppresses the growth of colorectal tumors in lab experiments, according to a new study. Wed, 27 Apr 2022 11:57:16 EDT //www.koonmotors.com/releases/2022/04/220427115716.htm //www.koonmotors.com/releases/2022/04/220418125556.htm Artificial intelligence reduced by twofold the rate at which precancerous polyps were missed in colorectal cancer screening, reported a team of international researchers. Mon, 18 Apr 2022 12:55:56 EDT //www.koonmotors.com/releases/2022/04/220418125556.htm //www.koonmotors.com/releases/2022/04/220414110750.htm In patients with familial adenomatous polyposis, a genetic disease predisposing to colon cancer, mutations of the APC gene induce the formation of intestinal polyps, but also reduce immune system activity. In a new study, researchers describe the mechanisms that modify the structure of T lymphocytes and hinder their migration towards the tumors to be destroyed. This discovery provides new perspectives on the migration of immune cells, a key process in antitumor immune defense. Thu, 14 Apr 2022 11:07:50 EDT //www.koonmotors.com/releases/2022/04/220414110750.htm //www.koonmotors.com/releases/2022/04/220405102834.htm Many cancers exhibit high levels of the reverse transcriptase enzyme. Single-agent lamivudine, a reverse transcriptase inhibitor, stopped disease progression in over 25% of patients with fourth-line refractory metastatic colorectal cancer. These results provide evidence for the evaluation of reverse transcriptase inhibitors as a new class of anti-cancer drugs. Tue, 05 Apr 2022 10:28:34 EDT //www.koonmotors.com/releases/2022/04/220405102834.htm //www.koonmotors.com/releases/2022/03/220331121238.htm Scientists identify a pathway of immune cell inhibition that may provide the basis for novel approaches to immunotherapy of colon cancer. Their results also highlight important roles of the intestinal microbiota in the development of the disease. Thu, 31 Mar 2022 12:12:38 EDT //www.koonmotors.com/releases/2022/03/220331121238.htm //www.koonmotors.com/releases/2022/03/220322122803.htm Accelerated glucose uptake and metabolism, known as the Warburg effect, is a feature of a small group of non-dividing cells within a colon cancer tumor. Intestinal cancer cells rely on Warburg glycolysis to eliminate toxic reactive oxidative species, not to provide energy to rapidly dividing cells. Since cancer metabolism is a heterogeneous feature within cancer cells, new research and study tools are needed. Tue, 22 Mar 2022 12:28:03 EDT //www.koonmotors.com/releases/2022/03/220322122803.htm //www.koonmotors.com/releases/2022/03/220310100008.htm New research has identified that the frequently used chemotherapy drug (5-FU or Fluorouracil) is 100 per cent more effective at targeting tumors (rather than surrounding tissues) when administered using an optimized liposomal formulation. Thu, 10 Mar 2022 10:00:08 EST //www.koonmotors.com/releases/2022/03/220310100008.htm //www.koonmotors.com/releases/2022/03/220304144643.htm Researchers have developed a new fluorescent label that gives a clearer picture of how DNA architecture is disrupted in cancer cells. The findings could improve cancer diagnoses for patients and classification of future cancer risk. Fri, 04 Mar 2022 14:46:43 EST //www.koonmotors.com/releases/2022/03/220304144643.htm //www.koonmotors.com/releases/2022/03/220303112205.htm A new meta-analysis, or data examination of several independent studies, adds to evidence that taller adults may be more likely than shorter ones to develop colorectal cancer or colon polyps that can later become malignant. Thu, 03 Mar 2022 11:22:05 EST //www.koonmotors.com/releases/2022/03/220303112205.htm //www.koonmotors.com/releases/2022/02/220228114359.htm 许多人不得不采用他汀类药物降低cholesterol levels. But statins may be able to do even more: Researchers report that these drugs inhibit a gene that promotes cancer cell metastasis. Mon, 28 Feb 2022 11:43:59 EST //www.koonmotors.com/releases/2022/02/220228114359.htm //www.koonmotors.com/releases/2022/02/220215125457.htm Researchers surveyed and compared early- and late-stage breast and colorectal cancer diagnoses in patients in pre-pandemic 2019 and in 2020, the first full year of the COVID-19 pandemic, discovering fewer of the former and more of the latter as patients delayed care. Tue, 15 Feb 2022 12:54:57 EST //www.koonmotors.com/releases/2022/02/220215125457.htm //www.koonmotors.com/releases/2022/02/220211102636.htm Using a technique called spatial transcriptomics, researchers have analyzed the gene expression in the mouse colon and created a map showing where in the tissue individual genes are expressed. When they superimposed previously known human transcription data onto the map, the researchers gained new insights into inflammatory bowel disease (IBD). Fri, 11 Feb 2022 10:26:36 EST //www.koonmotors.com/releases/2022/02/220211102636.htm //www.koonmotors.com/releases/2022/01/220119121414.htm Rising numbers of young men and women aged under 50 suffering from gastrointestinal cancers -- as reflected in a new study in South Australia -- is worrying international experts. The long-term SA Cancer Registry data provides compelling evidence of a 'significant' increase in young-onset (18--50 years) gastrointestinal adenocarcinomas (cancers) over the past three decades. Wed, 19 Jan 2022 12:14:14 EST //www.koonmotors.com/releases/2022/01/220119121414.htm //www.koonmotors.com/releases/2022/01/220112121515.htm The discovery raises the possibility that some of the roughly two million new cases of colorectal cancer every year around the world originate from brief and seemingly mild food-poisoning events. Wed, 12 Jan 2022 12:15:15 EST //www.koonmotors.com/releases/2022/01/220112121515.htm //www.koonmotors.com/releases/2022/01/220107152110.htm A team of researchers has revealed some of the mechanisms by which polyps develop into colorectal cancer, setting the framework for improved surveillance for the cancer utilizing precision medicine. Their study describes findings from a single-cell transcriptomic and imaging atlas of the two most common colorectal polyps found in humans: conventional adenomas and serrated polyps. Fri, 07 Jan 2022 15:21:10 EST //www.koonmotors.com/releases/2022/01/220107152110.htm //www.koonmotors.com/releases/2021/12/211214135056.htm 结直肠癌患者在冷杉st to receive targeted therapies. These drugs aim to block the cancer-causing proteins that trigger out-of-control cell growth while sparing healthy tissues. But some patients are not eligible for these treatments because they have cancer-promoting mutations that are believed to cause resistance to these drugs. Now, physician-scientists have used computer modeling and cell studies to discover that more patients may be helped by a common class of targeted therapies than previously thought. Tue, 14 Dec 2021 13:50:56 EST //www.koonmotors.com/releases/2021/12/211214135056.htm //www.koonmotors.com/releases/2021/12/211213133339.htm Recently published research has found that most cancer-free individuals over age 60 carry at least 100 billion cells harboring at least one oncogenic, or tumor-causing, mutation. Mon, 13 Dec 2021 13:33:39 EST //www.koonmotors.com/releases/2021/12/211213133339.htm //www.koonmotors.com/releases/2021/12/211202113459.htm Bacterium common in the mouse gut microbiome can charge up the immune system to fight cancer cells in the colon. Thu, 02 Dec 2021 11:34:59 EST //www.koonmotors.com/releases/2021/12/211202113459.htm //www.koonmotors.com/releases/2021/11/211118203604.htm Immune checkpoint inhibitors strengthen the immune response against cancer cells, but the medications are ineffective against certain tumors. Results from a new clinical trial indicate that adding radiation may overcome this resistance to immune checkpoint inhibitors. Thu, 18 Nov 2021 20:36:04 EST //www.koonmotors.com/releases/2021/11/211118203604.htm //www.koonmotors.com/releases/2021/11/211104162559.htm New findings help better understand the how one of the most commonly mutated genetic drivers of cancer passes signals that cause the disease. Thu, 04 Nov 2021 16:25:59 EDT //www.koonmotors.com/releases/2021/11/211104162559.htm //www.koonmotors.com/releases/2021/10/211020083946.htm A new deep learning algorithm can pick up the molecular pathways and development of key mutations causing colorectal cancer more accurately than existing methods, meaning patients could benefit from targeted therapies with quicker turnaround times and at a lower cost. Wed, 20 Oct 2021 08:39:46 EDT //www.koonmotors.com/releases/2021/10/211020083946.htm //www.koonmotors.com/releases/2021/10/211014102027.htm A new report finds more than 46,000 cancer cases annually in the United States could be prevented if Americans met the 5 hours per week of moderate-intensity recommended physical activity guidelines. Thu, 14 Oct 2021 10:20:27 EDT //www.koonmotors.com/releases/2021/10/211014102027.htm //www.koonmotors.com/releases/2021/10/211006160055.htm The compound works by hindering a key pathway that cancer cells rely upon to hoard energy, and is already undergoing clinical trials. Wed, 06 Oct 2021 16:00:55 EDT //www.koonmotors.com/releases/2021/10/211006160055.htm //www.koonmotors.com/releases/2021/09/210928102241.htm Classic antidepressants could help improve modern cancer treatments. They slowed the growth of pancreatic and colon cancers in mice, and when combined with immunotherapy, they even stopped the cancer growth long-term. In some cases the tumors disappeared completely, researchers have found. Their findings will now be tested in human clinical trials. Tue, 28 Sep 2021 10:22:41 EDT //www.koonmotors.com/releases/2021/09/210928102241.htm //www.koonmotors.com/releases/2021/09/210923082930.htm Brain metastasis occurs when cancer in one part of the body spreads to the brain. The lifetime incidence of such metastatic brain tumors in cancer patients is between 20%-45%, research shows. Thu, 23 Sep 2021 08:29:30 EDT //www.koonmotors.com/releases/2021/09/210923082930.htm //www.koonmotors.com/releases/2021/09/210917110850.htm Researchers are finding a link between the increased presence of certain bacteria in a gut biome and colon cancer. Fri, 17 Sep 2021 11:08:50 EDT //www.koonmotors.com/releases/2021/09/210917110850.htm //www.koonmotors.com/releases/2021/09/210913220129.htm First-degree relatives are 6 times more likely to be diagnosed with colon cancer before age 50, while second-degree relatives are 3 times more likely and third-degree relatives 1.56 times likelier. Mon, 13 Sep 2021 22:01:29 EDT //www.koonmotors.com/releases/2021/09/210913220129.htm //www.koonmotors.com/releases/2021/09/210913220104.htm Scientists have discovered a previously unknown pathway that prevents specific drugs from working in patients with bowel cancer. The research findings pave the way for increasing the number of bowel cancer patients who can be successfully treated, say the scientists. Mon, 13 Sep 2021 22:01:04 EDT //www.koonmotors.com/releases/2021/09/210913220104.htm //www.koonmotors.com/releases/2021/09/210901090057.htm There is a clear link between taking antibiotics and an increased risk of developing colon cancer within the next five to ten years. This has been confirmed after a study of 40,000 cancer cases. The impact of antibiotics on the intestinal microbiome is thought to lie behind the increased risk of cancer. 结婚,2021年9月01日09:00:57美国东部时间 //www.koonmotors.com/releases/2021/09/210901090057.htm //www.koonmotors.com/releases/2021/08/210819113037.htm ACE inhibitors, beta-blockers and thiazide diuretics were all associated with decreased mortality in patients with colorectal cancer. Thu, 19 Aug 2021 11:30:37 EDT //www.koonmotors.com/releases/2021/08/210819113037.htm //www.koonmotors.com/releases/2021/08/210817094147.htm Consuming higher amounts of Vitamin D -- mainly from dietary sources -- may help protect against developing young-onset colorectal cancer or precancerous colon polyps, according to a new study. Tue, 17 Aug 2021 09:41:47 EDT //www.koonmotors.com/releases/2021/08/210817094147.htm //www.koonmotors.com/releases/2021/08/210812123116.htm Researchers recently completed a study that has the potential to improve cancer treatment for colorectal cancer and melanoma by using nanotechnology to deliver chemotherapy in a way that makes it more effective against aggressive tumors. Thu, 12 Aug 2021 12:31:16 EDT //www.koonmotors.com/releases/2021/08/210812123116.htm //www.koonmotors.com/releases/2021/06/210624114342.htm Many people don't realize that the trillions of bacteria, viruses, and fungi residing within the gastrointestinal tract --collectively called the gut microbiome -- are connected to overall health, and specifically to cancer. Thu, 24 Jun 2021 11:43:42 EDT //www.koonmotors.com/releases/2021/06/210624114342.htm