//www.koonmotors.com/news/health_medicine/cholesterol/ Read the latest research on cholesterol levels, tests, and medications. Find out about cholesterol in your diet and research into new treatments for high cholesterol. en-us Fri, 08 Sep 2023 22:45:47 EDT Fri, 08 Sep 2023 22:45:47 EDT 60 //www.koonmotors.com/images/scidaily-logo-rss.png//www.koonmotors.com/news/health_medicine/cholesterol/ For more science news, visit ScienceDaily. //www.koonmotors.com/releases/2023/08/230830160820.htm People who have had a stroke called an intracerebral hemorrhage who take cholesterol-lowering drugs called statins may have a lower risk of having another stroke, especially ischemic stroke, compared to people who also had an intracerebral hemorrhage but were not taking statins. Wed, 30 Aug 2023 16:08:20 EDT //www.koonmotors.com/releases/2023/08/230830160820.htm //www.koonmotors.com/releases/2023/08/230830131658.htm Immunologists have uncovered new approaches to enhance protection from tumors and infections. They have revealed new insights into the metabolism of specialized cells of the immune system known as tissue-resident CD8 T cells and how they could be enhanced as immune defense weapons against tumors. Wed, 30 Aug 2023 13:16:58 EDT //www.koonmotors.com/releases/2023/08/230830131658.htm //www.koonmotors.com/releases/2023/08/230828105543.htm New research details the first oral drug for the treatment of a type of high cholesterol -- called Lp(a) -- that is a potentially more dangerous version of the so called 'bad' cholesterol, LDL, because it is stickier and may be more likely to cause blockages and blood clots in your arteries. It is estimated that up to 20% of people worldwide have high levels of Lp(a), which is associated with a person's risk of experiencing a heart attack, strokes or other serious cardiac event. Importantly Lp(a) can be present even in younger adults and otherwise healthy people with no other known cardiovascular risks -- and often remains undetected until a cardiac event has occurred. Mon, 28 Aug 2023 10:55:43 EDT //www.koonmotors.com/releases/2023/08/230828105543.htm //www.koonmotors.com/releases/2023/08/230809125629.htm Researchers have created a functional 'humanized' liver in living mice that will help scientists find human-specific mechanisms for regulating cholesterol levels and potentially for treating chronic liver diseases afflicting tens of millions of people in the United States. Wed, 09 Aug 2023 12:56:29 EDT //www.koonmotors.com/releases/2023/08/230809125629.htm //www.koonmotors.com/releases/2023/07/230726134219.htm 在老鼠身上进行的一项新研究发现取代传统protein sources with mealworms in high-fat diets could slow weight gain, improve immune response, reduce inflammation, enhance energy metabolism, and beneficially alter the ratio of good to bad cholesterol. Wed, 26 Jul 2023 13:42:19 EDT //www.koonmotors.com/releases/2023/07/230726134219.htm //www.koonmotors.com/releases/2023/07/230720124954.htm One of the world's largest studies on the impact of cholesterol-lowering medication has good and bad news for the 200 million people who take statins or other medication for high cholesterol. Thu, 20 Jul 2023 12:49:54 EDT //www.koonmotors.com/releases/2023/07/230720124954.htm //www.koonmotors.com/releases/2023/07/230707124650.htm A novel molecular pathway to explain how a mutation in the gene ACTA2 can cause individuals in their 30s -- with normal cholesterol levels and no other risk factors -- to develop coronary artery disease has now been identified,. Fri, 07 Jul 2023 12:46:50 EDT //www.koonmotors.com/releases/2023/07/230707124650.htm //www.koonmotors.com/releases/2023/07/230705171104.htm Older people who have fluctuating levels of cholesterol and triglycerides may have a higher risk of Alzheimer's disease and related dementias compared to people who have steady levels, according to new research. While the study found a link, it does not prove that fluctuating levels of cholesterol and triglycerides cause dementia. Wed, 05 Jul 2023 17:11:04 EDT //www.koonmotors.com/releases/2023/07/230705171104.htm //www.koonmotors.com/releases/2023/05/230523123635.htm CT scans are better at predicting a middle-aged person's risk for a heart disease, such as a heart attack, than genetics, reports a new study. Conventional measures of risk factor levels include blood pressure and cholesterol. Scientists had hoped genetics could better predict risk than conventional measure, but only when considering CT scan, half the study participants moved into the high-risk group. Tue, 23 May 2023 12:36:35 EDT //www.koonmotors.com/releases/2023/05/230523123635.htm //www.koonmotors.com/releases/2023/05/230504155632.htm Phytosterols are good for your health, but humans and other animals are not able to make them themselves, only plants can. To acquire phytosterols, humans are increasingly turning to supplements, green smoothies, or a Mediterranean diet with plenty of plant-based foods. Researchers have now discovered that tiny gutless worms from the Mediterranean can synthesize phytosterols on their own. Their study provides evidence that many other animals also have the genes needed to make their own phytosterols. Thu, 04 May 2023 15:56:32 EDT //www.koonmotors.com/releases/2023/05/230504155632.htm //www.koonmotors.com/releases/2023/05/230502090642.htm A new study analyzing data on over 20,000 U.S. adults links a healthier diet and increased exercise to weight loss that reduces heart disease risk -- while associating skipping meals and taking prescription diet pills with minimal weight loss, weight maintenance or weight gain. Tue, 02 May 2023 09:06:42 EDT //www.koonmotors.com/releases/2023/05/230502090642.htm //www.koonmotors.com/releases/2023/04/230424102055.htm Arterial stiffness may be a novel risk factor for metabolic syndrome in teens. Mon, 24 Apr 2023 10:20:55 EDT //www.koonmotors.com/releases/2023/04/230424102055.htm //www.koonmotors.com/releases/2023/04/230417142415.htm Researchers have found that a promising stroke therapy, known as antisense oligonucleotides, is preferentially taken up from the blood into areas of stroke damage in the brain when the molecules are linked to a specific kind of lipid. This therapy can be given relatively late after a stroke occurs, and is hoped to lead to reduced stroke-related disabilities. Mon, 17 Apr 2023 14:24:15 EDT //www.koonmotors.com/releases/2023/04/230417142415.htm //www.koonmotors.com/releases/2023/03/230328145442.htm Weight loss was associated with decreased risk factors for cardiovascular disease and Type 2 diabetes for at least five years -- even if some weight was regained, according to a review of research on behavioral weight loss programs. People who lost weight through an intensive behavioral weight loss program had lower systolic blood pressure levels, total cholesterol-to-good cholesterol ratio and HbA1c levels (a diabetes marker), when compared to people who did not participate in a program or participated in a lower-intensity behavioral program. Tue, 28 Mar 2023 14:54:42 EDT //www.koonmotors.com/releases/2023/03/230328145442.htm //www.koonmotors.com/releases/2023/03/230322140934.htm Chocolate bars, chips and fries - why can't we just ignore them in the supermarket? Researchers have now shown that foods with a high fat and sugar content change our brain: If we regularly eat even small amounts of them, the brain learns to consume precisely these foods in the future. Wed, 22 Mar 2023 14:09:34 EDT //www.koonmotors.com/releases/2023/03/230322140934.htm //www.koonmotors.com/releases/2023/03/230314205339.htm Scientists reversed infertility in sterile mice by reducing HDL cholesterol with a bacterial protein in a promising development that shows further evidence linking high cholesterol to female infertility. The researchers worked with a protein called serum opacity factor that lowered cholesterol levels by over 40% in three hours. Tue, 14 Mar 2023 20:53:39 EDT //www.koonmotors.com/releases/2023/03/230314205339.htm //www.koonmotors.com/releases/2023/02/230228113742.htm The study found that in patients at high risk of developing cardiovascular disease, over 20 percent refused to take statin medications. Women were about 20% more likely than men to refuse statin therapy when first suggested by their physician, and 50 percent more likely than men to never accept the recommendation. Tue, 28 Feb 2023 11:37:42 EST //www.koonmotors.com/releases/2023/02/230228113742.htm //www.koonmotors.com/releases/2023/01/230125121557.htm Researchers studying body phenotypes -- the observable characteristics like height, behavior, appearance and more measurables -- found that regardless of the muscle they had, high levels of fat mass in an individual were associated with poorer overall health. Wed, 25 Jan 2023 12:15:57 EST //www.koonmotors.com/releases/2023/01/230125121557.htm //www.koonmotors.com/releases/2023/01/230123123237.htm Soybean varieties with greater proportions of the protein B-conglycinin reduce plasma cholesterol levels and promote liver homeostasis, showing potential for preventing fatty liver disease and atherosclerosis, according to research by food scientists. Mon, 23 Jan 2023 12:32:37 EST //www.koonmotors.com/releases/2023/01/230123123237.htm //www.koonmotors.com/releases/2023/01/230119085845.htm A team of researchers has finally identified the molecular mechanism by which a key protein regulates LDL cholesterol. Thu, 19 Jan 2023 08:58:45 EST //www.koonmotors.com/releases/2023/01/230119085845.htm //www.koonmotors.com/releases/2023/01/230110150951.htm 学校由干预可以改善元bolic parameters such as blood sugar and cholesterol in children, according to a new study. Tue, 10 Jan 2023 15:09:51 EST //www.koonmotors.com/releases/2023/01/230110150951.htm //www.koonmotors.com/releases/2022/12/221219094912.htm An animal experiment demonstrates what big data analysis previously indicated: high doses of statins likely increase osteoporosis risk. Mon, 19 Dec 2022 09:49:12 EST //www.koonmotors.com/releases/2022/12/221219094912.htm //www.koonmotors.com/releases/2022/12/221213094752.htm A new study suggests lipoprotein(a) cholesterol may affect relationship between hypertension and cardiovascular disease risk. Tue, 13 Dec 2022 09:47:52 EST //www.koonmotors.com/releases/2022/12/221213094752.htm //www.koonmotors.com/releases/2022/12/221207163034.htm People who take cholesterol-lowering drugs called statins may have a lower risk of having a type of stroke called an intracerebral hemorrhage, according to a new study. An intracerebral hemorrhage is caused by bleeding in the brain. Wed, 07 Dec 2022 16:30:34 EST //www.koonmotors.com/releases/2022/12/221207163034.htm //www.koonmotors.com/releases/2022/12/221202112517.htm 随着圣诞节开始加大,研究hers are reminding people to prioritize a good night's sleep as new research shows that a troubled sleep may be associated with risk factors for type 2 diabetes. Fri, 02 Dec 2022 11:25:17 EST //www.koonmotors.com/releases/2022/12/221202112517.htm //www.koonmotors.com/releases/2022/11/221121215755.htm A study found that high-density lipoprotein (HDL) cholesterol, often called the 'good cholesterol,' may not be as effective as scientists once believed in uniformly predicting cardiovascular disease risk among adults of different racial and ethnic backgrounds. Mon, 21 Nov 2022 21:57:55 EST //www.koonmotors.com/releases/2022/11/221121215755.htm //www.koonmotors.com/releases/2022/11/221117141721.htm After statins, the next leading class of medications for managing cholesterol are PCSK9 inhibitors. These highly effective agents help the body pull excess cholesterol from the blood, but unlike statins, which are available as oral agents, PCSK9 inhibitors can only be administered as shots, creating barriers to their use. Now, a new study describes an orally administered small-molecule drug that reduces PCSK9 levels and lowers cholesterol in animal models by 70%. The findings represent a previously unrecognized strategy for managing cholesterol and may also impact cancer treatments. Thu, 17 Nov 2022 14:17:21 EST //www.koonmotors.com/releases/2022/11/221117141721.htm //www.koonmotors.com/releases/2022/11/221116133816.htm Researchers have found that honey improves key measures of cardiometabolic health, including blood sugar and cholesterol levels -- especially if the honey is raw and from a single floral source. Wed, 16 Nov 2022 13:38:16 EST //www.koonmotors.com/releases/2022/11/221116133816.htm //www.koonmotors.com/releases/2022/11/221107103237.htm After showing promise in early laboratory research, the cholesterol-lowering drug fenofibrate had no significant effect on COVID-19 outcomes in a multicenter international randomized clinical trial. Mon, 07 Nov 2022 10:32:37 EST //www.koonmotors.com/releases/2022/11/221107103237.htm //www.koonmotors.com/releases/2022/10/221020201437.htm The discovery of a genetic variant that is relatively common among people of Polynesian ancestry, but incredibly rare in most other populations, is giving clues to the genetic underpinnings of high cholesterol in all people, according to new research. Thu, 20 Oct 2022 20:14:37 EDT //www.koonmotors.com/releases/2022/10/221020201437.htm //www.koonmotors.com/releases/2022/10/221020112838.htm A study found that high aerobic fitness does not protect children from metabolic syndrome. The study also found that the amount of fat tissue in the body has distorted the results obtained in several previous studies on the protective effect of aerobic fitness from metabolic syndrome. The researchers also found that poor aerobic fitness is not a feature of metabolic syndrome in adults. Still, good aerobic fitness may indicate a lack of risk factors for metabolic syndrome. Thu, 20 Oct 2022 11:28:38 EDT //www.koonmotors.com/releases/2022/10/221020112838.htm //www.koonmotors.com/releases/2022/10/221017102359.htm For men and women, the risk factors for cardiovascular disease are largely the same, an extensive global study shows. Mon, 17 Oct 2022 10:23:59 EDT //www.koonmotors.com/releases/2022/10/221017102359.htm //www.koonmotors.com/releases/2022/09/220909094545.htm Women and men share most of the same risk factors for cardiovascular disease (CVD), a large international study has found -- the first such study to include people not only from high income countries, but also from low- and middle-income countries where the burden of CVD is the greatest. The global study assessed risk factors, including metabolic (such as high blood pressure, obesity and diabetes), behavioural (smoking and diet), and psychosocial (economic status and depression) in about 156,000 people without a history of CVD between the ages of 35 and 70. Living in 21 low, middle and high-income countries on five continents, they were followed for an average of 10 years. Fri, 09 Sep 2022 09:45:45 EDT //www.koonmotors.com/releases/2022/09/220909094545.htm //www.koonmotors.com/releases/2022/09/220907143344.htm A new study reveals how mechanical forces and tissue mechanics influence the morphology of the developing brain, and establishes a direct link in neural stem cells between Piezo1, a mechanically-activated ion channel, and intracellular cholesterol levels during neural development. Wed, 07 Sep 2022 14:33:44 EDT //www.koonmotors.com/releases/2022/09/220907143344.htm //www.koonmotors.com/releases/2022/09/220907133218.htm Elevated levels of per- and polyfluoroalkyl substances (PFAS) were associated with higher total cholesterol and non-HDL cholesterol in GenX Exposure Study participants' blood. The legacy PFAS chemicals PFOS and PFNA were most strongly associated with elevated cholesterol compared to the other chemicals, and the effects were more pronounced in older people. Wed, 07 Sep 2022 13:32:18 EDT //www.koonmotors.com/releases/2022/09/220907133218.htm //www.koonmotors.com/releases/2022/08/220825104816.htm Stopping statin treatment early could substantially reduce lifetime protection against heart disease since a large share of the benefit occurs later in life. That's the finding of a recent modelling study. Thu, 25 Aug 2022 10:48:16 EDT //www.koonmotors.com/releases/2022/08/220825104816.htm //www.koonmotors.com/releases/2022/07/220726132640.htm New research in people with a cluster of heart disease risk factors has shown that consuming green tea extract for four weeks can reduce blood sugar levels and improve gut health by lowering inflammation and decreasing 'leaky gut.' Tue, 26 Jul 2022 13:26:40 EDT //www.koonmotors.com/releases/2022/07/220726132640.htm //www.koonmotors.com/releases/2022/07/220718094433.htm People with gut disorders may be at greater risk of developing Alzheimer's Disease. A new study has confirmed the link between the two, which could lead to earlier detection and new potential treatments. Mon, 18 Jul 2022 09:44:33 EDT //www.koonmotors.com/releases/2022/07/220718094433.htm //www.koonmotors.com/releases/2022/07/220705162151.htm Eating one avocado a day for six months was found to have no effect on belly fat, liver fat or waist circumference in people with overweight or obesity, according to a new study. However, it did lead to a slight decrease in unhealthy cholesterol levels. Tue, 05 Jul 2022 16:21:51 EDT //www.koonmotors.com/releases/2022/07/220705162151.htm //www.koonmotors.com/releases/2022/06/220629084034.htm American Heart Association's checklist to measure cardiovascular health is updated, now called Life's Essential 8™, adding healthy sleep as essential for optimal cardiovascular health. Other health and lifestyle factors in the checklist, which were part of the previous, 7-item scoring tool, are nicotine exposure, physical activity, diet, weight, blood glucose, cholesterol and blood pressure. The new sleep metric suggests 7-9 hours of sleep daily for optimal cardiovascular health for adults, and more for children depending on age. Wed, 29 Jun 2022 08:40:34 EDT //www.koonmotors.com/releases/2022/06/220629084034.htm //www.koonmotors.com/releases/2022/06/220616101953.htm A new study shows targeting a protein in smooth muscle cells can block and decrease buildup of atherosclerotic plaque in mouse models, according to researchers. Thu, 16 Jun 2022 10:19:53 EDT //www.koonmotors.com/releases/2022/06/220616101953.htm //www.koonmotors.com/releases/2022/06/220615102900.htm Researchers used large-scale genotyping and exome sequencing from the UK Biobank to gain insight into the expected effects of long-term statin use on cataract risk. The analysis found that common genetic variants in more than 402,000 people, who were not taking statins, that mimic the effects of LDL-cholesterol lowering statins are associated with a higher risk of cataracts and cataract surgery. They also found that rare genetic mutations in 169,172 people, mimicking statin treatment, increased the risk of developing cataracts by nearly five times. Wed, 15 Jun 2022 10:29:00 EDT //www.koonmotors.com/releases/2022/06/220615102900.htm //www.koonmotors.com/releases/2022/06/220609131936.htm A genetic variant that is present in nearly 30% of Greenlanders is linked to high cholesterol and an increased risk of cardiovascular disease, according to a new study. Thu, 09 Jun 2022 13:19:36 EDT //www.koonmotors.com/releases/2022/06/220609131936.htm //www.koonmotors.com/releases/2022/06/220601092159.htm While there is some evidence that consuming omega-3 fatty acids in food or dietary supplements may reduce the risk of high blood pressure, the optimal amount to consume for this benefit is unclear. A review of dozens of studies suggests that the optimal amount of omega-3 fatty acids to consume to lower blood pressure is likely about 3 grams daily. Consuming higher amounts of omega-3 fatty acids may be beneficial for people at high risk for developing cardiovascular disease, though more research is needed researchers said. Wed, 01 Jun 2022 09:21:59 EDT //www.koonmotors.com/releases/2022/06/220601092159.htm //www.koonmotors.com/releases/2022/05/220524124839.htm Researchers have shown how moderate egg consumption can increase the amount of heart-healthy metabolites in the blood. Tue, 24 May 2022 12:48:39 EDT //www.koonmotors.com/releases/2022/05/220524124839.htm //www.koonmotors.com/releases/2022/05/220519164853.htm New research suggests high levels of dietary cholesterol make mice sicker when infected with influenza. This study links cholesterol in the diet with exacerbation of a viral infection. Thu, 19 May 2022 16:48:53 EDT //www.koonmotors.com/releases/2022/05/220519164853.htm //www.koonmotors.com/releases/2022/05/220519081109.htm Researchers have found that eating cranberries could improve memory, ward off dementia, and reduce 'bad' cholesterol. The research team studied the benefits of consuming the equivalent of a cup of cranberries a day among 50 to 80-year-olds. They hope that their findings could have implications for the prevention of neurodegenerative diseases such as dementia. Thu, 19 May 2022 08:11:09 EDT //www.koonmotors.com/releases/2022/05/220519081109.htm //www.koonmotors.com/releases/2022/05/220518113843.htm Health screening and genetic tests might identify more than 1 million U.S. adults who have familial hypercholesterolemia, a common genetic disorder that causes elevated bad cholesterol levels, which may lead to premature cardiovascular disease. Identifying familial hypercholesterolemia early in adulthood creates an opportunity for early treatment aimed at preventing heart attack and death, according to a new study. Wed, 18 May 2022 11:38:43 EDT //www.koonmotors.com/releases/2022/05/220518113843.htm //www.koonmotors.com/releases/2022/05/220515113212.htm Levels of bad cholesterol rise during menopause, and 10% of this increase is likely due to shifts in sex hormones. Women usually undergo menopause at the age of 48 to 52 years, leading to a decline in estrogen and increase in follicle-stimulating hormone (FSH). Menopause is thought to predispose women to heart disease since it typically develops 10 years later than in men, and risk rises after menopause. Sun, 15 May 2022 11:32:12 EDT //www.koonmotors.com/releases/2022/05/220515113212.htm //www.koonmotors.com/releases/2022/05/220511123540.htm 研究人员表明,不同病人的反应to statins can be explained by the variation in the human microbiome. The findings suggest that microbiome monitoring could be used to help optimize personalized statin treatments. Wed, 11 May 2022 12:35:40 EDT //www.koonmotors.com/releases/2022/05/220511123540.htm //www.koonmotors.com/releases/2022/05/220505180928.htm An analysis of 11 randomized trials finds that adhering to vegan diets for at least 12 weeks may boost weight loss and glucose control in adults with overweight or type 2 diabetes. Thu, 05 May 2022 18:09:28 EDT //www.koonmotors.com/releases/2022/05/220505180928.htm //www.koonmotors.com/releases/2022/04/220428125440.htm The health benefits of dietary fiber vary across individuals and may depend on the specific type of fiber and the dose consumed, researchers report. Thu, 28 Apr 2022 12:54:40 EDT //www.koonmotors.com/releases/2022/04/220428125440.htm //www.koonmotors.com/releases/2022/04/220428103941.htm Aspirin therapy, as opposed to statin use, for non-obstructive coronary artery disease does not reduce major cardiovascular events, according to a new study. Thu, 28 Apr 2022 10:39:41 EDT //www.koonmotors.com/releases/2022/04/220428103941.htm //www.koonmotors.com/releases/2022/04/220426101717.htm Using lipidomics, a modern analytical method, researchers identified those lipids that are statistically associated with cardiovascular disease and type 2 diabetes. In addition, the scientists found that a diet with an increased proportion of unsaturated fatty acids leads to a reduction in risk-associated lipids and an increase in low-risk lipids. Tue, 26 Apr 2022 10:17:17 EDT //www.koonmotors.com/releases/2022/04/220426101717.htm //www.koonmotors.com/releases/2022/04/220413141551.htm Cardiovascular risk factors are associated with an increased risk of depression in older adults, according to a new study. Wed, 13 Apr 2022 14:15:51 EDT //www.koonmotors.com/releases/2022/04/220413141551.htm //www.koonmotors.com/releases/2022/04/220411125401.htm A new study suggests a key protein molecule plays a major role in the accumulation of brain cholesterol, triggering the development of Alzheimer's and supporting the use of peptide inhibitors as a therapeutic treatment target. The study found that mice, when treated with the peptide inhibitor, demonstrated 50% restored memory function, based on testing such as navigating mazes. Mon, 11 Apr 2022 12:54:01 EDT //www.koonmotors.com/releases/2022/04/220411125401.htm //www.koonmotors.com/releases/2022/04/220406101723.htm After the Neolithic, European populations showed an increase in height and intelligence, reduced skin pigmentation and increased risk of cardiovascular disease due to genetic changes that lowered concentrations of 'good' HDL cholesterol. The changes reflect ongoing evolutionary processes in humans and highlight the impact the Neolithic revolution had on our lifestyle and health. Research of these past events offers interesting starting points for today's science and health care. Wed, 06 Apr 2022 10:17:23 EDT //www.koonmotors.com/releases/2022/04/220406101723.htm //www.koonmotors.com/releases/2022/04/220406101527.htm Five childhood risk factors that predict stroke and heart attacks in adulthood have been identified after being tracked for up to half a century in the world's largest international prospective cardiovascular disease study. Wed, 06 Apr 2022 10:15:27 EDT //www.koonmotors.com/releases/2022/04/220406101527.htm //www.koonmotors.com/releases/2022/04/220403121140.htm Findings from a phase 1 trial show that an experimental 'gene silencing' therapy reduced blood levels of lipoprotein(a), a key driver of heart disease risk, by up to 98%. Sun, 03 Apr 2022 12:11:40 EDT //www.koonmotors.com/releases/2022/04/220403121140.htm //www.koonmotors.com/releases/2022/03/220323160653.htm Parkinsonism is a term for a group of neurological conditions that cause movement problems including tremors, slowed movement and stiffness, with Parkinson's disease being one of the better knowns causes. A new study suggests that older people taking statin drugs have a lower chance of developing parkinsonism later compared to people who were not taking statins. Wed, 23 Mar 2022 16:06:53 EDT //www.koonmotors.com/releases/2022/03/220323160653.htm