//www.koonmotors.com/news/health_medicine/cancer/ Read the latest medical research on risk factors for cancer, cancer symptoms, treatments and more. Updated daily. en-us Sun, 10 Sep 2023 20:16:03 EDT Sun, 10 Sep 2023 20:16:03 EDT 60 //www.koonmotors.com/images/scidaily-logo-rss.png//www.koonmotors.com/news/health_medicine/cancer/ For more science news, visit ScienceDaily. //www.koonmotors.com/releases/2023/09/230907162605.htm Some patients have experienced incredible recoveries after CAR-T-cell therapy. But they've also endured incredibly strong and scary side effects, in part because of the lymphodepleting chemotherapy that is performed before the CAR-T-cells are reinfused. What if CAR-T-cell therapy could be performed without lymphodepleting chemotherapy? Thu, 07 Sep 2023 16:26:05 EDT //www.koonmotors.com/releases/2023/09/230907162605.htm //www.koonmotors.com/releases/2023/09/230907130337.htm Scientists are reporting results from a Phase I trial in an area of promising research for Alzheimer's disease -- cellular senescence. Thu, 07 Sep 2023 13:03:37 EDT //www.koonmotors.com/releases/2023/09/230907130337.htm //www.koonmotors.com/releases/2023/09/230907130332.htm By adding synergistic self-adjuvanting properties to Covid-19 RNA vaccines, researchers showed they could significantly boost the immune response generated in mice. Thu, 07 Sep 2023 13:03:32 EDT //www.koonmotors.com/releases/2023/09/230907130332.htm //www.koonmotors.com/releases/2023/09/230907105834.htm A new nanocomplex renders a tumor harmless -- and, on top of that, it trains the immune system to detect and eliminate metastases. Thu, 07 Sep 2023 10:58:34 EDT //www.koonmotors.com/releases/2023/09/230907105834.htm //www.koonmotors.com/releases/2023/09/230907105827.htm Herpes is not only unpleasant but it can, in some cases, also have dangerous complications and life-threatening consequences. A research team has now introduced a completely new approach for treating herpes. Their method is based on the inhibition of an enzyme that is needed for the release of newly formed virus particles from infected cells. Thu, 07 Sep 2023 10:58:27 EDT //www.koonmotors.com/releases/2023/09/230907105827.htm //www.koonmotors.com/releases/2023/09/230907105810.htm Early findings of two studies shed light on new ways to anticipate recurrence in HPV-positive head and neck cancer sooner. Thu, 07 Sep 2023 10:58:10 EDT //www.koonmotors.com/releases/2023/09/230907105810.htm //www.koonmotors.com/releases/2023/09/230906143449.htm Researchers have designed a device that can help test treatments in patients with gliomas, a type of tumor that originates in the brain or spinal cord. Wed, 06 Sep 2023 14:34:49 EDT //www.koonmotors.com/releases/2023/09/230906143449.htm //www.koonmotors.com/releases/2023/09/230906135554.htm The treadmill exercise test with electrocardiogram (ECG), also known as an exercise stress test, is one of the most familiar tests in medicine. While exercise testing typically is focused on diagnosing coronary artery disease, a recent study finds that exercise test abnormalities, such as low functional aerobic capacity, predicted non-cardiovascular causes of death such as cancer in addition to cardiovascular-related deaths. Wed, 06 Sep 2023 13:55:54 EDT //www.koonmotors.com/releases/2023/09/230906135554.htm //www.koonmotors.com/releases/2023/09/230906112440.htm Human immune cells are capable of coordinating their own movement more independently than previously thought. Researchers discovered that immune cells do not just passively follow the chemical cues in their environment. Quite the contrary, they can also shape these cues and navigate in complex environments in a self-organized manner. Wed, 06 Sep 2023 11:24:40 EDT //www.koonmotors.com/releases/2023/09/230906112440.htm //www.koonmotors.com/releases/2023/09/230906112428.htm Scientists identified new set of molecules that drive the growth of human pancreatic cancer cell lines, explaining how genetic mutations can activate genetic 'super-enhancers' that promote out-of-control pancreatic cancer growth. They show the efficacy of an experimental drug that targets a super-enhancer related protein, demonstrating the promise of therapeutics that block the effects of super-enhancers. Wed, 06 Sep 2023 11:24:28 EDT //www.koonmotors.com/releases/2023/09/230906112428.htm //www.koonmotors.com/releases/2023/09/230905155711.htm An essential protein that acts as a gatekeeper for calcium entering cells promotes the growth of oral cancer and generates pain, according to a new study. Targeting this protein -- the ORAI1 calcium channel -- could provide a new approach to treating oral cancer, which causes persistent pain that worsens as it progresses. Tue, 05 Sep 2023 15:57:11 EDT //www.koonmotors.com/releases/2023/09/230905155711.htm //www.koonmotors.com/releases/2023/09/230905124935.htm Cancers, degenerative diseases: deregulation of our cells' internal communication pathways is at the root of many conditions. Microtubules -- microscopic protein filaments -- play a crucial role in controlling these exchanges. However, their mechanisms remain poorly understood. A team has identified a new mechanism, involving two proteins, that governs their growth. The discovery opens up unprecedented prospects for the development of new treatments that can act at the very heart of cells. Tue, 05 Sep 2023 12:49:35 EDT //www.koonmotors.com/releases/2023/09/230905124935.htm //www.koonmotors.com/releases/2023/09/230905124910.htm Using a standardized assessment, researchers in the UK compared the performance of a commercially available artificial intelligence algorithm with human readers of screening mammograms. Tue, 05 Sep 2023 12:49:10 EDT //www.koonmotors.com/releases/2023/09/230905124910.htm //www.koonmotors.com/releases/2023/09/230904104625.htm Scientists have discovered two new genes that cause head and neck cancer patients to be resistant to chemotherapy, and that silencing either gene can make cancer cells previously unresponsive to chemotherapy subsequently respond to it. Mon, 04 Sep 2023 10:46:25 EDT //www.koonmotors.com/releases/2023/09/230904104625.htm //www.koonmotors.com/releases/2023/09/230904104617.htm A new cancer therapy attacks tumors by tricking cancer cells into absorbing a snippet of RNA that naturally blocks cell division. Mon, 04 Sep 2023 10:46:17 EDT //www.koonmotors.com/releases/2023/09/230904104617.htm //www.koonmotors.com/releases/2023/09/230901124042.htm A study sheds new light on why tumors that have spread to the brain from other parts of the body respond to immunotherapy while glioblastoma, an aggressive cancer that originates in the brain, does not. 星期五,2023年9月01日12:40:42 EDT //www.koonmotors.com/releases/2023/09/230901124042.htm //www.koonmotors.com/releases/2023/08/230831164436.htm Biochemical researchers have identified a new function of a key protein that leads to cancer -- a finding they believe could lead to more effective treatments for a range of cancers and other diseases. Thu, 31 Aug 2023 16:44:36 EDT //www.koonmotors.com/releases/2023/08/230831164436.htm //www.koonmotors.com/releases/2023/08/230831142858.htm A broad new strategy could hold hope for treating virtually all blood cancers with CAR T cell therapy, which is currently approved for five subtypes of blood cancer. Scientists have demonstrated the potential efficacy of this approach a preclinical study. Thu, 31 Aug 2023 14:28:58 EDT //www.koonmotors.com/releases/2023/08/230831142858.htm //www.koonmotors.com/releases/2023/08/230831142816.htm Vitamin C and other antioxidants stimulate the formation of new blood vessels in lung cancer tumors, a new study shows. The discovery corroborates the idea that dietary supplements containing antioxidants can accelerate tumor growth and metastasis. Thu, 31 Aug 2023 14:28:16 EDT //www.koonmotors.com/releases/2023/08/230831142816.htm //www.koonmotors.com/releases/2023/08/230831121759.htm The mechanism by which breast cancer is formed in the cells of mammalian epithelium has been discovered. Although roughly 20 mutations accumulate annually in each epithelial cell until menopause, the mutation rate significantly decreases after menopause. Accumulation also decreased after childbirth, suggesting the effect of estrogen in mammary epithelium. Thu, 31 Aug 2023 12:17:59 EDT //www.koonmotors.com/releases/2023/08/230831121759.htm //www.koonmotors.com/releases/2023/08/230831121757.htm A novel study has identified a range of metabolic biomarkers that could help predict the risk of cancer. Thu, 31 Aug 2023 12:17:57 EDT //www.koonmotors.com/releases/2023/08/230831121757.htm //www.koonmotors.com/releases/2023/08/230831121720.htm A new study examines why people living in Atlantic regions are more at-risk for developing melanoma than other Canadians, providing lessons on skin cancer prevention for the whole country. To find out why, the researchers compared UV exposure and behaviours among different groups in Atlantic Canada based on income, education, and gender, among other factors. Thu, 31 Aug 2023 12:17:20 EDT //www.koonmotors.com/releases/2023/08/230831121720.htm //www.koonmotors.com/releases/2023/08/230831121640.htm 科学家们发现一些mul机制tiple myelomas become resistant to initially effective T-cell therapies. Thu, 31 Aug 2023 12:16:40 EDT //www.koonmotors.com/releases/2023/08/230831121640.htm //www.koonmotors.com/releases/2023/08/230831121621.htm A lab is developing more accurate and powerful liquid biopsy technologies that take advantage of signals from RNA 'dark matter,' an understudied area of the genome. 星期四,2023年8月31日12:16:21美国东部时间 //www.koonmotors.com/releases/2023/08/230831121621.htm //www.koonmotors.com/releases/2023/08/230830131950.htm Australian researchers have found an existing blood cancer drug can kill 'silent' HIV cells and delay reinfections -- a significant pre-clinical discovery that could lead to a future cure for the disease. Wed, 30 Aug 2023 13:19:50 EDT //www.koonmotors.com/releases/2023/08/230830131950.htm //www.koonmotors.com/releases/2023/08/230830131911.htm A new study suggests that extreme dietary habits involving carbohydrates and fats affect life expectancy. Researchers found that a low carbohydrate intake in men and a high carbohydrate intake in women are associated with a higher risk of all-cause and cancer-related mortality and that women with higher fat intake may have a lower risk of all-cause mortality. Their findings suggest that people should pursue a balanced diet rather than heavily restricting their carbohydrate or fat intake. Wed, 30 Aug 2023 13:19:11 EDT //www.koonmotors.com/releases/2023/08/230830131911.htm //www.koonmotors.com/releases/2023/08/230830131855.htm Fresh discoveries about a type of immune cells could give lung cancer patients a more accurate prognosis and better identify who will benefit from immunotherapies. Researchers found that the location in and around tumours of cytotoxic T cells, which play a key role in fighting cancer, may help predict patient survival and indicate whether or not treatments will work. Wed, 30 Aug 2023 13:18:55 EDT //www.koonmotors.com/releases/2023/08/230830131855.htm //www.koonmotors.com/releases/2023/08/230830131703.htm A new study suggests that cognitive loss in patients with brain metastases may be due to the interference that cancer produces in neuronal circuits. When cancer spreads in the brain, it changes the brain's chemistry, interfering with the communication between neurons. This is a very different hypothesis from the one previously accepted, with implications for the diagnosis and treatment of brain metastases. The authors have used artificial intelligence to show that metastasis alters brain activity. Wed, 30 Aug 2023 13:17:03 EDT //www.koonmotors.com/releases/2023/08/230830131703.htm //www.koonmotors.com/releases/2023/08/230830131653.htm Researchers have identified stem cells in the human thymus for the first time. These cells represent a potential new target to understand immune diseases and cancer and how to boost the immune system. Wed, 30 Aug 2023 13:16:53 EDT //www.koonmotors.com/releases/2023/08/230830131653.htm //www.koonmotors.com/releases/2023/08/230829125956.htm Selective targeting of cancerous cells poses major clinical challenges during cancer therapy. However, this limitation can be overcome by using bioengineered bacteria with highly optimized chemical modifications. A recent study demonstrates the use of chemically modified purple photosynthetic bacteria for the successful detection and elimination of colon cancer cells in a mouse model. The study also sheds light on the underlying mechanism of action. Tue, 29 Aug 2023 12:59:56 EDT //www.koonmotors.com/releases/2023/08/230829125956.htm //www.koonmotors.com/releases/2023/08/230829125932.htm Early laboratory results in mice show the drug PXS-5505 increases survival when combined with chemotherapy in the treatment of pancreatic ductal adenocarcinomas. Tue, 29 Aug 2023 12:59:32 EDT //www.koonmotors.com/releases/2023/08/230829125932.htm //www.koonmotors.com/releases/2023/08/230828162352.htm Researchers have looked beyond biochemistry to publish groundbreaking work on the physics of fat droplets found inside many types of cells, revealing them to be a potential threat to a cell's nucleus.They have discovered fat-filled lipid droplets' surprising capability to indent and puncture the nucleus, the organelle which contains and regulates a cell's DNA. The stakes of their findings are high: a ruptured nucleus can lead to elevated DNA damage that is characteristic of many diseases, including cancer. Mon, 28 Aug 2023 16:23:52 EDT //www.koonmotors.com/releases/2023/08/230828162352.htm //www.koonmotors.com/releases/2023/08/230828162330.htm Scientists have successfully transformed rhabdomyosarcoma cells into healthy functioning muscle cells. Could this lab breakthrough help bring differentiation therapy to the clinic? If so, a new and safer way to fight cancer may be on the horizon. Mon, 28 Aug 2023 16:23:30 EDT //www.koonmotors.com/releases/2023/08/230828162330.htm //www.koonmotors.com/releases/2023/08/230828105517.htm Scientists have verified the anticancer effects of Kencur, a tropical plant of the ginger family, mainly grown in Southeast Asia, in cell and animal experiments. They found that Kencur extract and its main active components significantly inhibit cancer cell growth at the cellular and animal levels. Furthermore, the involvement of TFAM in the mechanism of action was confirmed. Mon, 28 Aug 2023 10:55:17 EDT //www.koonmotors.com/releases/2023/08/230828105517.htm //www.koonmotors.com/releases/2023/08/230825122044.htm 'Eco-friendly' paper drinking straws contain long-lasting and potentially toxic chemicals, a new study has concluded. Fri, 25 Aug 2023 12:20:44 EDT //www.koonmotors.com/releases/2023/08/230825122044.htm //www.koonmotors.com/releases/2023/08/230824120153.htm A bitter taste in the mouth is often a symptom or side effect of illness, which may be the result of how the body reacts to pathogens. A new study sheds light on the mechanisms involved in the complex interplay between taste perception and immune function. Their work also highlights the potential of a sequencing tool for investigating epigenetic mechanisms that affect taste-cell gene expression. Thu, 24 Aug 2023 12:01:53 EDT //www.koonmotors.com/releases/2023/08/230824120153.htm //www.koonmotors.com/releases/2023/08/230824111920.htm 研究人员已经发现了一个功能角色KRAS mutations in pancreatic cancer and rapidly translated these findings into a novel therapeutic approach combining a KRAS G12D inhibitor with immune checkpoint inhibitors for early- and late-stage KRAS G12D-mutant pancreatic cancer. The combination therapy led to durable tumor elimination and significantly improved survival outcomes in preclinical models, leading to the launch of a Phase I clinical trial. Thu, 24 Aug 2023 11:19:20 EDT //www.koonmotors.com/releases/2023/08/230824111920.htm //www.koonmotors.com/releases/2023/08/230824111917.htm For many patients, the internet serves as a powerful tool for self-education on medical topics. With ChatGPT now at patients' fingertips, researchers assessed how consistently the artificial intelligence chatbot provides recommendations for cancer treatment that align with National Comprehensive Cancer Network (NCCN) guidelines. Thu, 24 Aug 2023 11:19:17 EDT //www.koonmotors.com/releases/2023/08/230824111917.htm //www.koonmotors.com/releases/2023/08/230824111914.htm Researchers have uncovered a connection between the topography of the human genome and the presence of mutations in human cancer. Just as different terrains on Earth foster distinct ecosystems, certain regions in the genome seem to provide an environment for specific mutations to thrive. Thu, 24 Aug 2023 11:19:14 EDT //www.koonmotors.com/releases/2023/08/230824111914.htm //www.koonmotors.com/releases/2023/08/230824111908.htm Gene therapy with microRNA-22 produced better survival outcomes than the current FDA-approved drug for liver cancer and without noticeable toxicity in new mouse study. Thu, 24 Aug 2023 11:19:08 EDT //www.koonmotors.com/releases/2023/08/230824111908.htm //www.koonmotors.com/releases/2023/08/230823165409.htm An international phase 3 clinical trial found that a new targeted treatment called zolbetuximab, given in combination with a standard chemotherapy, extended survival for patients with advanced gastric or gastroesophageal junction cancer that overexpressed a specific biomarker. Wed, 23 Aug 2023 16:54:09 EDT //www.koonmotors.com/releases/2023/08/230823165409.htm //www.koonmotors.com/releases/2023/08/230823165402.htm In a groundbreaking endeavor, researchers have successfully transferred a longevity gene from naked mole rats to mice, resulting in improved health and an extension of the mouse's lifespan. The research opens exciting possibilities for unlocking the secrets of aging and extending human lifespan. Wed, 23 Aug 2023 16:54:02 EDT //www.koonmotors.com/releases/2023/08/230823165402.htm //www.koonmotors.com/releases/2023/08/230823122619.htm Immunotherapies for cancer aim to induce the immune system to combat cancer cells more effectively. A research team has now described a new, modular strategy for T-cell-based immunotherapy that manages to work without complex genetic modifications. Modulation of cell-cell communications through an ingenious regulatory circuit using various small, specially folded DNA molecules (aptamers) causes cancer cells to directly activate their mortal enemies, T cells. Wed, 23 Aug 2023 12:26:19 EDT //www.koonmotors.com/releases/2023/08/230823122619.htm //www.koonmotors.com/releases/2023/08/230823122523.htm A study has discovered a new relationship between cancer cells and the immune system, and shows how cancer can selfishly hijack a normally helpful immune pathway. Wed, 23 Aug 2023 12:25:23 EDT //www.koonmotors.com/releases/2023/08/230823122523.htm //www.koonmotors.com/releases/2023/08/230822193054.htm AI can predict certain forms of esophageal and stomach cancer. Tue, 22 Aug 2023 19:30:54 EDT //www.koonmotors.com/releases/2023/08/230822193054.htm //www.koonmotors.com/releases/2023/08/230822151743.htm Scientists have discovered a potential target for gastric cancers associated with Epstein-Barr Virus. Tue, 22 Aug 2023 15:17:43 EDT //www.koonmotors.com/releases/2023/08/230822151743.htm //www.koonmotors.com/releases/2023/08/230822111728.htm Researchers have discovered how high-fat diets can change gut bacteria and alter digestive molecules called bile acids that are modified by those bacteria, predisposing mice to colorectal cancer. The findings bring scientists closer to understanding the causes of and how to prevent colorectal cancer. Tue, 22 Aug 2023 11:17:28 EDT //www.koonmotors.com/releases/2023/08/230822111728.htm //www.koonmotors.com/releases/2023/08/230821232426.htm Using MRI as a screening test alongside PSA density allowed detection of cancers that would have been missed by the blood test alone, according to new research. Mon, 21 Aug 2023 23:24:26 EDT //www.koonmotors.com/releases/2023/08/230821232426.htm //www.koonmotors.com/releases/2023/08/230821174259.htm 额外的速度COVID-19助推器needed for cancer patients depends on the treatment they are receiving, researchers say. Mon, 21 Aug 2023 17:42:59 EDT //www.koonmotors.com/releases/2023/08/230821174259.htm //www.koonmotors.com/releases/2023/08/230821135730.htm A research team has developed a new approach that integrates a minimally invasive, painless microneedle platform capable of absorbing the cell-surrounding, biomarker-containing fluid from deeper layers of the skin with an ultra-sensitive, single-molecule detection method (Simoa) that detects often rare, yet relevant biomarkers with higher sensitivity than conventional methods. Mon, 21 Aug 2023 13:57:30 EDT //www.koonmotors.com/releases/2023/08/230821135730.htm //www.koonmotors.com/releases/2023/08/230821114358.htm Anti-estrogenic therapies can suppress the growth of cancer that does not express estrogen receptors; when combined with immune checkpoint inhibitor therapies, they halt tumor progression in mice models. Mon, 21 Aug 2023 11:43:58 EDT //www.koonmotors.com/releases/2023/08/230821114358.htm //www.koonmotors.com/releases/2023/08/230818134137.htm According to new research, T cells have a nuclear receptor doing something very odd—but very important—to help them fight pathogens and destroy cancer cells. This receptor, called retinoic acid receptor alpha, is known to control gene expression programs in the nucleus, but it also now appears to operate outside the cell nucleus to coordinate the early events triggered at the cell surface that lead to T cell activation. Fri, 18 Aug 2023 13:41:37 EDT //www.koonmotors.com/releases/2023/08/230818134137.htm //www.koonmotors.com/releases/2023/08/230817164043.htm Scientists have identified how low levels of the TET2 gene fuel the rapid growth of acute myeloid leukemia in animal models. Thu, 17 Aug 2023 16:40:43 EDT //www.koonmotors.com/releases/2023/08/230817164043.htm //www.koonmotors.com/releases/2023/08/230817164033.htm 研究人员发现一些早期的女性, low-risk breast cancer may not need radiotherapy after breast conserving surgery. Thu, 17 Aug 2023 16:40:33 EDT //www.koonmotors.com/releases/2023/08/230817164033.htm //www.koonmotors.com/releases/2023/08/230816170623.htm People who adhere to a Mediterranean lifestyle -- which includes a diet rich in fruits, vegetables, and whole grains; healthy eating habits like limiting added salts and sugars; and habits promoting adequate rest, physical activity, and socialization -- have a lower risk of all-cause and cancer mortality, according to a new study. People who adhered to the lifestyle's emphasis on rest, exercise, and socializing with friends had a lower risk of cardiovascular disease mortality. Wed, 16 Aug 2023 17:06:23 EDT //www.koonmotors.com/releases/2023/08/230816170623.htm //www.koonmotors.com/releases/2023/08/230816160003.htm Scientists have uncovered how a newly discovered gene, NEK1, in which mutations have been linked to ALS cases, disrupts the function of the motor neuron and causes it to degenerate and die. Wed, 16 Aug 2023 16:00:03 EDT //www.koonmotors.com/releases/2023/08/230816160003.htm //www.koonmotors.com/releases/2023/08/230816114107.htm Researchers have found a potential drug candidate that improved outcomes for patients with a type of childhood brain tumor for which there are no effective treatments. The compound, called ONC201, nearly doubled survival for patients with diffuse midline glioma (DMG) or diffuse intrinsic pontine glioma (DIPG), compared to previous patients. Wed, 16 Aug 2023 11:41:07 EDT //www.koonmotors.com/releases/2023/08/230816114107.htm //www.koonmotors.com/releases/2023/08/230815151137.htm Researchers demonstrate how mathematical modeling combined with dynamic biomarkers can be used to characterize metastatic disease and identify appropriate therapeutic approaches to improve patient outcomes. Tue, 15 Aug 2023 15:11:37 EDT //www.koonmotors.com/releases/2023/08/230815151137.htm //www.koonmotors.com/releases/2023/08/230815151117.htm In a development that could accelerate the discovery of new diagnostics and treatments, researchers have developed a versatile and low-cost technology for targeted sequencing of full-length RNA molecules. The technology, called TEQUILA-seq, is highly cost-effective compared to commercially available solutions for targeted RNA sequencing and can be adapted for different research and clinical purposes. Tue, 15 Aug 2023 15:11:17 EDT //www.koonmotors.com/releases/2023/08/230815151117.htm //www.koonmotors.com/releases/2023/08/230815131824.htm New cancer drugs are being launched at a rapid pace, before their long-term effectiveness for patients can be evaluated. Several years later, most of them still lack scientific evidence for actually increasing life expectancy or improving quality of life. Tue, 15 Aug 2023 13:18:24 EDT //www.koonmotors.com/releases/2023/08/230815131824.htm