//www.koonmotors.com/news/health_medicine/breast_cancer/ Breast cancer research including information on breast cancer symptoms, prevention strategies, screening techniques, and new breast cancer treatments. en-us Wed, 06 Sep 2023 14:45:57 EDT Wed, 06 Sep 2023 14:45:57 EDT 60 //www.koonmotors.com/images/scidaily-logo-rss.png//www.koonmotors.com/news/health_medicine/breast_cancer/ For more science news, visit ScienceDaily. //www.koonmotors.com/releases/2023/09/230905124910.htm Using a standardized assessment, researchers in the UK compared the performance of a commercially available artificial intelligence algorithm with human readers of screening mammograms. Tue, 05 Sep 2023 12:49:10 EDT //www.koonmotors.com/releases/2023/09/230905124910.htm //www.koonmotors.com/releases/2023/09/230904104625.htm Scientists have discovered two new genes that cause head and neck cancer patients to be resistant to chemotherapy, and that silencing either gene can make cancer cells previously unresponsive to chemotherapy subsequently respond to it. Mon, 04 Sep 2023 10:46:25 EDT //www.koonmotors.com/releases/2023/09/230904104625.htm //www.koonmotors.com/releases/2023/08/230831121759.htm The mechanism by which breast cancer is formed in the cells of mammalian epithelium has been discovered. Although roughly 20 mutations accumulate annually in each epithelial cell until menopause, the mutation rate significantly decreases after menopause. Accumulation also decreased after childbirth, suggesting the effect of estrogen in mammary epithelium. Thu, 31 Aug 2023 12:17:59 EDT //www.koonmotors.com/releases/2023/08/230831121759.htm //www.koonmotors.com/releases/2023/08/230821114358.htm Anti-estrogenic therapies can suppress the growth of cancer that does not express estrogen receptors; when combined with immune checkpoint inhibitor therapies, they halt tumor progression in mice models. Mon, 21 Aug 2023 11:43:58 EDT //www.koonmotors.com/releases/2023/08/230821114358.htm //www.koonmotors.com/releases/2023/08/230818135200.htm Women with larger breasts tend to exercise less frequently and avoid high-intensity exercise and a new study has found much improved participation in recreational group exercises after breast reduction surgery. The new study further strengthens calls for more accessible, publicly funded breast reduction and other interventions in some cases. Fri, 18 Aug 2023 13:52:00 EDT //www.koonmotors.com/releases/2023/08/230818135200.htm //www.koonmotors.com/releases/2023/08/230817164033.htm Researchers have found some women with early-stage, low-risk breast cancer may not need radiotherapy after breast conserving surgery. Thu, 17 Aug 2023 16:40:33 EDT //www.koonmotors.com/releases/2023/08/230817164033.htm //www.koonmotors.com/releases/2023/08/230809130647.htm A collaborative study provides compelling evidence that combining an investigational oral drug with standard-of-care medications reverts hormone resistance and increases Rx effectiveness in experimental models of estrogen-receptor positive (ER+) and triple-negative breast cancers (TNBC), respectively. Wed, 09 Aug 2023 13:06:47 EDT //www.koonmotors.com/releases/2023/08/230809130647.htm //www.koonmotors.com/releases/2023/08/230803213822.htm Chronic exposure to fine particulate air pollutants (PM2.5) and nitrogen dioxide (NO2) may increase non-lung cancer risk in older adults, according to new research. In a cohort study of millions of Medicare beneficiaries, the researchers found that exposures to PM2.5 and NO2 over a 10-year period increased the risk of developing colorectal and prostate cancers. The researchers also found that even low levels of air pollution exposure may make people particularly susceptible to developing these cancers, in addition to breast and endometrial cancers. Thu, 03 Aug 2023 21:38:22 EDT //www.koonmotors.com/releases/2023/08/230803213822.htm //www.koonmotors.com/releases/2023/08/230801200759.htm Mammography screening supported by artificial intelligence (AI) is a safe alternative to today's conventional double reading by radiologists and can reduce heavy workloads for doctors. This has now been shown in an interim analysis of a prospective, randomised controlled trial, which addressed the clinical safety of using AI in mammography screening. Tue, 01 Aug 2023 20:07:59 EDT //www.koonmotors.com/releases/2023/08/230801200759.htm //www.koonmotors.com/releases/2023/07/230731110747.htm Scientists have identified a protein that plays a pivotal role in the action of several emerging cancer therapies. The researchers say the discovery will likely aid efforts to fine-tune the use of immunotherapies against several challenging cancers. Mon, 31 Jul 2023 11:07:47 EDT //www.koonmotors.com/releases/2023/07/230731110747.htm //www.koonmotors.com/releases/2023/07/230728170625.htm In hopes of improving the survival rate for breast cancer patients, researchers designed a wearable ultrasound device that could allow women to detect tumors when they are still in early stages. Fri, 28 Jul 2023 17:06:25 EDT //www.koonmotors.com/releases/2023/07/230728170625.htm //www.koonmotors.com/releases/2023/07/230721113230.htm Scientists have discovered a possible way to block proteins produced in the body when a patient has cancer and which causes its spread to other parts of the body. Fri, 21 Jul 2023 11:32:30 EDT //www.koonmotors.com/releases/2023/07/230721113230.htm //www.koonmotors.com/releases/2023/07/230719112621.htm Women diagnosed and treated for breast cancer have increased biological aging compared to women who remain free of breast cancer, according to a new study. Among women diagnosed with breast cancer, the association with faster biological aging was most pronounced for those who received radiation therapy, while surgery showed no association with biological aging. This finding suggests that developing cancer is not what increases the aging effect. Wed, 19 Jul 2023 11:26:21 EDT //www.koonmotors.com/releases/2023/07/230719112621.htm //www.koonmotors.com/releases/2023/06/230628130349.htm A new study has created the world's largest and most comprehensive map of normal breast tissue, providing an unprecedented understanding of mammary biology that may help identify therapeutic targets for diseases such as breast cancer. The Human Breast Cell Atlas used single-cell and spatial genomic methods to profile more than 714,000 cells from 126 women. The breast atlas highlights 12 major cell types and 58 biological cell states, and identifies differences based on ethnicity, age and the menopause status of healthy women. Wed, 28 Jun 2023 13:03:49 EDT //www.koonmotors.com/releases/2023/06/230628130349.htm //www.koonmotors.com/releases/2023/06/230621121024.htm Researchers have outlined the structure and function of a protein complex which is required to repair damaged DNA and protect against cancer. Wed, 21 Jun 2023 12:10:24 EDT //www.koonmotors.com/releases/2023/06/230621121024.htm //www.koonmotors.com/releases/2023/05/230517122057.htm Researchers trace the origin of certain breast cancers to genomic reshuffling -- rearrangement of chromosomes -- that activates cancer genes and ignites disease. The finding offers a long-missing explanation for many cases of the disease that remain unexplained by the classical model of breast cancer development. The study shows the sex hormone estrogen -- thus far thought to be only a fuel for breast cancer growth -- can directly cause tumor-driving genomic rearrangements. Wed, 17 May 2023 12:20:57 EDT //www.koonmotors.com/releases/2023/05/230517122057.htm //www.koonmotors.com/releases/2023/05/230504094944.htm Researchers discover a mechanism by which cancer cells escape the immune system. Thu, 04 May 2023 09:49:44 EDT //www.koonmotors.com/releases/2023/05/230504094944.htm //www.koonmotors.com/releases/2023/03/230322082721.htm There is a relative increase of 20% to 30% in breast cancer risk associated with both combined and progesterone-only contraceptives, whatever the mode of delivery, though with five years of use, the 15-year absolute excess incidence is at most 265 cases per 100,000 users, according to a new study. Wed, 22 Mar 2023 08:27:21 EDT //www.koonmotors.com/releases/2023/03/230322082721.htm //www.koonmotors.com/releases/2023/03/230316212552.htm The combination of two oral medications has shown positive results in people with prostate cancer, whose disease has spread to other parts of the body. Compared with XTANDI plus placebo, the investigatory combination of TALZENNA and XTANDI demonstrated a statistically significant and clinically meaningful improvement in radiographic progression-free survival. Thu, 16 Mar 2023 21:25:52 EDT //www.koonmotors.com/releases/2023/03/230316212552.htm //www.koonmotors.com/releases/2023/03/230313120939.htm Scientists have discovered why breast cancer cells that have spread to the lungs may 'wake up' following years of sleep -- forming incurable secondary tumors. Their research reveals the mechanism that triggers this breast cancer 'time bomb' -- and suggests a strategy to defuse it. Mon, 13 Mar 2023 12:09:39 EDT //www.koonmotors.com/releases/2023/03/230313120939.htm //www.koonmotors.com/releases/2023/03/230308112149.htm Researchers have identified a way to treat the area surrounding breast tumors that have spread to bone so that such tumors become vulnerable to attack by the body's immune system. When the researchers boosted the activity of certain immune cells, called T cells and macrophages, these immune cells worked together to clear metastatic breast tumors that had spread to the bones of mice. Wed, 08 Mar 2023 11:21:49 EST //www.koonmotors.com/releases/2023/03/230308112149.htm //www.koonmotors.com/releases/2023/03/230308112101.htm New insights into the effects of a hormonal treatment on transgender men could have implications for the treatment of breast cancer. Wed, 08 Mar 2023 11:21:01 EST //www.koonmotors.com/releases/2023/03/230308112101.htm //www.koonmotors.com/releases/2023/02/230222210537.htm An interdisciplinary collaboration 10 years in the making used a materials science approach to 'fingerprint' the calcium mineral deposits known as microcalcifications that reveal pathological clues to the progression of breast cancer and potentially other diseases. Wed, 22 Feb 2023 21:05:37 EST //www.koonmotors.com/releases/2023/02/230222210537.htm //www.koonmotors.com/releases/2023/02/230207144246.htm Engineers have developed artificial intelligence (AI) technology to predict if women with breast cancer would benefit from chemotherapy prior to surgery. Tue, 07 Feb 2023 14:42:46 EST //www.koonmotors.com/releases/2023/02/230207144246.htm //www.koonmotors.com/releases/2023/01/230111150754.htm CAR T cell therapy may enhance the effectiveness surgery for of solid tumors, according to a preclinical study. Wed, 11 Jan 2023 15:07:54 EST //www.koonmotors.com/releases/2023/01/230111150754.htm //www.koonmotors.com/releases/2022/12/221208114744.htm Researchers have revealed how the gene HOXA5 may work to suppress formation of breast cancers. Thu, 08 Dec 2022 11:47:44 EST //www.koonmotors.com/releases/2022/12/221208114744.htm //www.koonmotors.com/releases/2022/12/221205153751.htm While it has long been recognized that drugs that block the cancer-promoting activity of estrogen reduce risk of developing new breast cancers, a new computer modeling study has shown that these treatments could also reduce the risk of dying from the disease in women who are at high risk. Mon, 05 Dec 2022 15:37:51 EST //www.koonmotors.com/releases/2022/12/221205153751.htm //www.koonmotors.com/releases/2022/12/221201082151.htm In a study using a mouse model of aging that mimics breast cancer development in estrogen receptor-positive post-menopausal women, investigators have determined that over-expression, or switching on of the Esr1 gene, could lead to elevated risk of developing estrogen receptor-positive breast cancer in older women. Thu, 01 Dec 2022 08:21:51 EST //www.koonmotors.com/releases/2022/12/221201082151.htm //www.koonmotors.com/releases/2022/11/221121105225.htm 放射治疗已成为一个重要组成部分of breast cancer treatment but can lead to cancer-related fatigue and negatively impact patients' health-related quality of life. Research has revealed exercise may make the treatment more tolerable for patients. Mon, 21 Nov 2022 10:52:25 EST //www.koonmotors.com/releases/2022/11/221121105225.htm //www.koonmotors.com/releases/2022/11/221118114843.htm Researchers mapping a molecular atlas for ductal carcinoma in situ (DCIS) have made a major advance toward distinguishing whether the early pre-cancers in the breast will develop into invasive cancers or remain stable. Fri, 18 Nov 2022 11:48:43 EST //www.koonmotors.com/releases/2022/11/221118114843.htm //www.koonmotors.com/releases/2022/11/221117084409.htm Cancer that splits and develops in new organs around the body becomes significantly more difficult to fight. Now, researchers have shown that these metastatic cancers, that spread from the original, adapt their metabolism to the tissue in which they grow. The discovery represents a breakthrough for the understanding of metastatic cancer and is an important piece of the puzzle in the search for more effective treatments. Thu, 17 Nov 2022 08:44:09 EST //www.koonmotors.com/releases/2022/11/221117084409.htm //www.koonmotors.com/releases/2022/11/221115113932.htm Error-prone DNA replication and repair may lead to mutations and cancer in individuals who inherit a mutant copy of the BRCA1 gene, according to a new study. The discovery has potential implications for preventing the development of cancer in patients with these mutations. Tue, 15 Nov 2022 11:39:32 EST //www.koonmotors.com/releases/2022/11/221115113932.htm //www.koonmotors.com/releases/2022/11/221111103017.htm New research has found variable voltages in the membranes of breast cancer cells, revealing clues about how they grow and spread. Fri, 11 Nov 2022 10:30:17 EST //www.koonmotors.com/releases/2022/11/221111103017.htm //www.koonmotors.com/releases/2022/11/221110205408.htm Researchers have discovered factors that may make breast and ovarian cancers associated with BRCA1/2 gene mutations more likely to recur. Thu, 10 Nov 2022 20:54:08 EST //www.koonmotors.com/releases/2022/11/221110205408.htm //www.koonmotors.com/releases/2022/11/221110114323.htm A team of researchers has developed a nanotechnology platform that can change the way the immune system sees solid tumor cells, making them more receptive to immunotherapy. The preclinical findings suggest this adaptable immune conversion approach has the potential for broad application across many cancer types. Thu, 10 Nov 2022 11:43:23 EST //www.koonmotors.com/releases/2022/11/221110114323.htm //www.koonmotors.com/releases/2022/11/221110101812.htm 癌细胞的生长和扩散的嗡嗡声an body, they need proteins that bind copper ions. New research about how cancer-related proteins bind the metal and how they interact with other proteins, opens up potential new drug targets in the fight against cancer. Thu, 10 Nov 2022 10:18:12 EST //www.koonmotors.com/releases/2022/11/221110101812.htm //www.koonmotors.com/releases/2022/11/221109124338.htm Researchers have created a tool that maps how breast cancer grows in previously unseen detail, and highlights how the cells around the tumor may be the key to controlling the spread of disease. Wed, 09 Nov 2022 12:43:38 EST //www.koonmotors.com/releases/2022/11/221109124338.htm //www.koonmotors.com/releases/2022/11/221107135812.htm A new treatment may significantly enhance the efficacy of chemotherapy in breast cancer patients, reducing the risk for lung metastasis following chemo from 52% to only 6%. Conducted in an animal model, the study identified the mechanism that generates a cancer-promoting inflammatory environment in response to chemotherapy. Moreover, the researchers found that by adding an anti-inflammatory agent to the chemotherapy, metastasis can be prevented. Mon, 07 Nov 2022 13:58:12 EST //www.koonmotors.com/releases/2022/11/221107135812.htm //www.koonmotors.com/releases/2022/11/221107083259.htm Using DNA barcodes to track cancer cells through time, scientists have shown that cells within a cancer have diverse abilities to escape immune system defenses. Mon, 07 Nov 2022 08:32:59 EST //www.koonmotors.com/releases/2022/11/221107083259.htm //www.koonmotors.com/releases/2022/11/221103104958.htm A study shows there are 2.5 times as many breast cancer survivors in Canada today as there were in 2007 -- a success story that brings some new health challenges. Thu, 03 Nov 2022 10:49:58 EDT //www.koonmotors.com/releases/2022/11/221103104958.htm //www.koonmotors.com/releases/2022/10/221031124634.htm Researchers have found that a system based on ion-sensitive field effect transistors -- a tiny electrical circuit that is activated by a change in pH -- and enzymatic chemical signal amplification can accurately detect EGFR on breast cancer cells. This technology has the potential to be used with multiple markers simultaneously to assess cancer patient status from liquid biopsy samples. 星期一,2022年10月31日12:46:34美国东部时间 //www.koonmotors.com/releases/2022/10/221031124634.htm //www.koonmotors.com/releases/2022/10/221031104416.htm The risk of developing breast cancer is higher in what are known as dense breasts, which appear white in mammograms, than in nondense breasts, which appear grey. Researchers have now shown that there are major biological differences dense breasts and nondense breasts. The results suggest that the properties of dense breasts promote cancer growth. Mon, 31 Oct 2022 10:44:16 EDT //www.koonmotors.com/releases/2022/10/221031104416.htm //www.koonmotors.com/releases/2022/10/221028111614.htm Researchers have identified that finger-like cellular extensions called filopodia contribute to building a barrier surrounding breast tumors. Fri, 28 Oct 2022 11:16:14 EDT //www.koonmotors.com/releases/2022/10/221028111614.htm //www.koonmotors.com/releases/2022/10/221027154154.htm Medical researchers have developed new chemical compounds that show promise in a potential anticancer therapy to treat aggressive tumors. Thu, 27 Oct 2022 15:41:54 EDT //www.koonmotors.com/releases/2022/10/221027154154.htm //www.koonmotors.com/releases/2022/10/221025201140.htm Patients with early-stage breast cancer who had a pathologic complete response (pCR) to neoadjuvant chemotherapy may be able to skip surgery and receive standard radiation treatment with a low chance of disease recurrence, according to a new study. 星期二,2022年10月25日20:11:40美国东部时间 //www.koonmotors.com/releases/2022/10/221025201140.htm //www.koonmotors.com/releases/2022/10/221025165658.htm Researchers have developed a drug that so specifically targets a deadly kind of breast cancer that there are little to no toxic side effects. Next, it will be tested in phase 1 clinical trials in humans. Tue, 25 Oct 2022 16:56:58 EDT //www.koonmotors.com/releases/2022/10/221025165658.htm //www.koonmotors.com/releases/2022/10/221025153406.htm Researchers have set their sights on a new therapeutic target for an aggressive form of breast cancer with limited treatment options. Through a comprehensive and cutting-edge genomic screening method known as CRISPR/CAS9 screening, scientists were able to identify a specific enzyme called UBA1 that revealed itself as an ideal therapeutic target. Using a novel UBA-inhibiting drug called TAK-243, they blocked the cellular function of UBA1 and effectively killed cancer cells in patient-derived breast tumors in mice. Tue, 25 Oct 2022 15:34:06 EDT //www.koonmotors.com/releases/2022/10/221025153406.htm //www.koonmotors.com/releases/2022/10/221021132749.htm 一项新的研究可能会促使医学专家反思when to start mammograms for women who have a mother, sister or daughter diagnosed with breast cancer. Fri, 21 Oct 2022 13:27:49 EDT //www.koonmotors.com/releases/2022/10/221021132749.htm //www.koonmotors.com/releases/2022/10/221018131115.htm Researchers have successfully 3D bioprinted breast cancer tumors and treated them in a breakthrough study to better understand the disease that is one of the leading causes of mortality worldwide. Tue, 18 Oct 2022 13:11:15 EDT //www.koonmotors.com/releases/2022/10/221018131115.htm //www.koonmotors.com/releases/2022/10/221017102356.htm Research reports a combination of a novel small inhibitory molecule and an FDA-approved chemotherapy drug suppresses the growth of triple-negative breast cancer cells synergistically. Mon, 17 Oct 2022 10:23:56 EDT //www.koonmotors.com/releases/2022/10/221017102356.htm //www.koonmotors.com/releases/2022/10/221017102353.htm Women who used chemical hair straightening products were at higher risk for uterine cancer compared to women who did not report using these products, according to a new study. The researchers found no associations with uterine cancer for other hair products that the women reported using, including hair dyes, bleach, highlights, or perms. Mon, 17 Oct 2022 10:23:53 EDT //www.koonmotors.com/releases/2022/10/221017102353.htm //www.koonmotors.com/releases/2022/10/221014135656.htm A study has determined the role that fibroblasts, the cells that contribute to tissue formation, play in a tumor's ability to generate resistance to the most common biological treatment for HER2. The paper demonstrates the ability of a new therapy, currently undergoing clinical trials, to promote a potent immune response by binding to the fibroblasts, enabling it to overcome resistance to anti-HER2 therapy in tumors with this cancer cell protection mechanism. Fri, 14 Oct 2022 13:56:56 EDT //www.koonmotors.com/releases/2022/10/221014135656.htm //www.koonmotors.com/releases/2022/10/221014135613.htm A multi-center analysis of patients with invasive lobular carcinoma, or ILC -- the second most common histological subtype of invasive breast cancer in the U.S. -- showed that, despite its prevalence, ILC is detected later and has worse outcomes than the predominant subtype of invasive breast cancer, known as invasive ductal carcinoma (IDC), or no special type. Fri, 14 Oct 2022 13:56:13 EDT //www.koonmotors.com/releases/2022/10/221014135613.htm //www.koonmotors.com/releases/2022/09/220930163202.htm Higher levels of a key inflammatory marker were related to older breast cancer survivors reporting cognitive problems, researchers found in one of the first long-term efforts to examine the potential link between chronic inflammation and cognition in older breast cancer survivors. Fri, 30 Sep 2022 16:32:02 EDT //www.koonmotors.com/releases/2022/09/220930163202.htm //www.koonmotors.com/releases/2022/09/220923121702.htm Fat cells, or adipocytes, that grow in close proximity to breast cancers can shift into other cell types that promote tumor growth, a new study suggests. The findings could lead to new ways to fight breast cancer, a disease that is diagnosed in more than 300,000 U.S. women each year and kills nearly 45,000 annually. Fri, 23 Sep 2022 12:17:02 EDT //www.koonmotors.com/releases/2022/09/220923121702.htm //www.koonmotors.com/releases/2022/09/220922124505.htm An unhealthy gut triggers changes in normal breast tissue that helps breast cancer spread to other parts of the body, new research reveals. Thu, 22 Sep 2022 12:45:05 EDT //www.koonmotors.com/releases/2022/09/220922124505.htm //www.koonmotors.com/releases/2022/09/220920115558.htm Scientists have uncovered a mechanism by which certain breast cancer cells regulate their own metastases, fuel dissemination from the original tumor site, and determine routes to invade distant organs such as the lungs, according to a new study. Tue, 20 Sep 2022 11:55:58 EDT //www.koonmotors.com/releases/2022/09/220920115558.htm //www.koonmotors.com/releases/2022/09/220914102238.htm A two-pronged approach to imaging breast density in mice resulted in better detection of changes in breast tissue, including spotting early signs of cancer. The researchers hope that this approach will be translated from mice and improve breast imaging for people; it may also help with prognosis of disease as density can be linked to specific patterns of mammary gland growth, including signs of cancer development. Wed, 14 Sep 2022 10:22:38 EDT //www.koonmotors.com/releases/2022/09/220914102238.htm //www.koonmotors.com/releases/2022/09/220913183130.htm Researchers developed three different computer models to predict how a hypothetical set of 10,000 patients with specific types of metastatic breast cancer would respond to different sequences and types of chemotherapy. They determined that giving standard chemotherapy drugs in a specific sequence for some types of metastatic breast cancer can help reduce overall costs and improve the value of care while preserving quality of life. Tue, 13 Sep 2022 18:31:30 EDT //www.koonmotors.com/releases/2022/09/220913183130.htm //www.koonmotors.com/releases/2022/09/220912132329.htm The HSD3B1 gene could hold clues for predicting and treating endometrial cancer, according to a novel finding. Researchers found a certain HSD3B1 genotype was more common in women with type 2 endometrial cancer. Those patients show lower survival rates than those diagnosed with type 1 endometrial cancer, likely driven by the fact that type 2 patient cells are less hormone-dependent. 星期一,2022年9月12日13:23:29 EDT //www.koonmotors.com/releases/2022/09/220912132329.htm