Brain Tumor News -- ScienceDaily //www.koonmotors.com/news/health_medicine/brain_tumor/ What are the risks, symptoms and treatment options for brain tumors and other cancers? Read current medical research and news articles on brain tumor surgery and related information. en-us Fri, 08 Sep 2023 11:45:52 EDT Fri, 08 Sep 2023 11:45:52 EDT 60 Brain Tumor News -- ScienceDaily //www.koonmotors.com/images/scidaily-logo-rss.png//www.koonmotors.com/news/health_medicine/brain_tumor/ For more science news, visit ScienceDaily. Microdevices implanted into tumors offer new way to treat brain cancer //www.koonmotors.com/releases/2023/09/230906143449.htm Researchers have designed a device that can help test treatments in patients with gliomas, a type of tumor that originates in the brain or spinal cord. Wed, 06 Sep 2023 14:34:49 EDT //www.koonmotors.com/releases/2023/09/230906143449.htm Study could help explain why certain brain tumors don't respond well to immunotherapy //www.koonmotors.com/releases/2023/09/230901124042.htm A study sheds new light on why tumors that have spread to the brain from other parts of the body respond to immunotherapy while glioblastoma, an aggressive cancer that originates in the brain, does not. Fri, 01 Sep 2023 12:40:42 EDT //www.koonmotors.com/releases/2023/09/230901124042.htm Using the body's 'invisible scalpel' to remove brain cancer //www.koonmotors.com/releases/2023/08/230811115425.htm Scientists discovered that anti-CTLA-4 immunotherapy extended the lives of mice with glioblastoma by causing specialized CD4+ T immune cells to 1) infiltrate the brain and 2) tell brain-resident immune cells called microglia to destroy tumor cells. Their findings show the benefit of harnessing the body's own immune cells to fight brain cancer and could lead to more effective immunotherapies. Fri, 11 Aug 2023 11:54:25 EDT //www.koonmotors.com/releases/2023/08/230811115425.htm Efficient boron neutron capture therapy for brain tumor with novel boron carrier //www.koonmotors.com/releases/2023/07/230713142031.htm A new boron agent drastically improves the effectiveness of boron neutron capture therapy for glioblastoma. The agent is selectively absorbed by brain tumor cells, exhibits enhanced blood retention, and can be administered at low doses. Experiments on cell cultures, mice, and rats show promising results, highlighting the potential of the novel agent for radiotherapy. Thu, 13 Jul 2023 14:20:31 EDT //www.koonmotors.com/releases/2023/07/230713142031.htm AI tool decodes brain cancer's genome during surgery //www.koonmotors.com/releases/2023/07/230707111646.htm New AI tool enables in-surgery genomic profiling of gliomas, the most aggressive and most common brain tumors. This information offers critical clues about how aggressive a cancer is, its future behavior, and its likely response to treatment. The tool can provide real-time guidance to surgeons on the optimal surgical approach for removal of cancerous tissue. Fri, 07 Jul 2023 11:16:46 EDT //www.koonmotors.com/releases/2023/07/230707111646.htm 疫苗提供了一个促进T细胞疗法 //www.koonmotors.com/releases/2023/07/230705115136.htm A new vaccine boosts the response of engineered CAR-T cells and helps the immune system generate T cells that target other tumor antigens. The researchers found this approach made it more likely that a tumor can be eradicated in mice. Wed, 05 Jul 2023 11:51:36 EDT //www.koonmotors.com/releases/2023/07/230705115136.htm Urine tests identify brain tumors by capturing cancer DNA using nanowires //www.koonmotors.com/releases/2023/07/230703132622.htm A group led by researchers at Nagoya University in Japan used nanowires to develop a technology for capturing cell-free DNA from cancer cells in urine samples. Using their technique, they captured this DNA and successfully detected the IDH1 mutation, a characteristic genetic mutation of brain tumors. Their findings show a safe, effective, and non-invasive way of diagnosing brain tumors. Mon, 03 Jul 2023 13:26:22 EDT //www.koonmotors.com/releases/2023/07/230703132622.htm New discovery can help detect brain tumors //www.koonmotors.com/releases/2023/06/230615105312.htm Folate-based radiopharmaceuticals can be used in positron emission tomography (PET) imaging to detect folate receptors in brain tumours. The discovery of folate receptors and their exploitation potential with respect to brain tumours is a new and significant finding in the field. Thu, 15 Jun 2023 10:53:12 EDT //www.koonmotors.com/releases/2023/06/230615105312.htm Biodegradable ultrasound opens the blood-brain barrier //www.koonmotors.com/releases/2023/06/230614220548.htm A new, biodegradable ultrasound far more powerful than previous devices could make brain cancers more treatable, researchers report. Wed, 14 Jun 2023 22:05:48 EDT //www.koonmotors.com/releases/2023/06/230614220548.htm Breakthrough in glioblastoma treatment with the help of a virus //www.koonmotors.com/releases/2023/06/230612200332.htm Researchers are describing the results of a recent clinical trial -- a breakthrough in glioblastoma treatment with the help of a modified cold virus injected directly into the tumor. When combined with an immunotherapy drug, the authors observed a subset of patients that appeared to be living longer as a result of this therapy. Mon, 12 Jun 2023 20:03:32 EDT //www.koonmotors.com/releases/2023/06/230612200332.htm New drug delays progression of glioma, a deadly brain cancer //www.koonmotors.com/releases/2023/06/230605181002.htm Scientists have shown that a new targeted therapy drug can extend the amount of time people with a subtype of glioma are on treatment without their cancer worsening. The finding suggests a possible new treatment option for people with the slow-growing but deadly brain tumor. Mon, 05 Jun 2023 18:10:02 EDT //www.koonmotors.com/releases/2023/06/230605181002.htm Open-analysis platform for pediatric brain tumors provides robust data resource for childhood cancer research //www.koonmotors.com/releases/2023/05/230531150122.htm Researchers have partnered to create a first-of-its-kind open-source, reproducible analysis platform for pediatric brain tumors. With the help of thousands of genomically sequenced samples, researchers have used this platform to identify initial findings about genetic variants associated with poorer outcomes that could help guide future diagnostic and therapeutic advances. Wed, 31 May 2023 15:01:22 EDT //www.koonmotors.com/releases/2023/05/230531150122.htm Scientists discover a deadly brain cancer's hidden weakness //www.koonmotors.com/releases/2023/05/230512110206.htm The difficult-to-treat brain cancer glioblastoma steals a person's mental faculties as it spreads, yet the tumor's insidious ability to infiltrate neighboring networks in the brain could also prove its undoing. Fri, 12 May 2023 11:02:06 EDT //www.koonmotors.com/releases/2023/05/230512110206.htm Novel ultrasound uses microbubbles to open blood-brain barrier to treat glioblastoma in humans //www.koonmotors.com/releases/2023/05/230504111921.htm In the first in-human clinical trial, scientists used a novel, skull-implantable ultrasound device to open the blood-brain barrier and repeatedly permeate large, critical regions of the human brain to deliver chemotherapy that was injected intravenously. This is potentially a huge advance for glioblastoma patients because the most potent chemotherapy can't permeate the blood-brain barrier to reach the aggressive and deadly brain tumor. Thu, 04 May 2023 11:19:21 EDT //www.koonmotors.com/releases/2023/05/230504111921.htm This gel stops brain tumors in mice. Could it offer hope for humans? //www.koonmotors.com/releases/2023/04/230424162901.htm Medication delivered by a novel gel cured 100% of mice with an aggressive brain cancer, a striking result that offers new hope for patients diagnosed with glioblastoma, one of the deadliest and most common brain tumors in humans. Mon, 24 Apr 2023 16:29:01 EDT //www.koonmotors.com/releases/2023/04/230424162901.htm Researchers leverage cell self-destruction to treat brain tumors //www.koonmotors.com/releases/2023/04/230407094232.htm Medical researchers have found that glioblastoma tumor cells are particularly sensitive to ferroptosis -- a type of cell death that can be triggered by removing certain amino acids from the diet. Fri, 07 Apr 2023 09:42:32 EDT //www.koonmotors.com/releases/2023/04/230407094232.htm Artificial intelligence predicts genetics of cancerous brain tumors in under 90 seconds //www.koonmotors.com/releases/2023/03/230323135437.htm Using artificial intelligence, researchers have discovered how to screen for genetic mutations in cancerous brain tumors in under 90 seconds -- and possibly streamline the diagnosis and treatment of gliomas, a study suggests. The newly developed system, DeepGlioma, identified mutations used by the World Health Organization to define molecular subgroups of diffuse glioma with an average accuracy over 90%. Thu, 23 Mar 2023 13:54:37 EDT //www.koonmotors.com/releases/2023/03/230323135437.htm Scientists develop novel approach to enhance drug delivery for brain tumors in children //www.koonmotors.com/releases/2023/03/230302114149.htm Researchers have developed a new drug delivery approach that uses nanoparticles to enable more effective and targeted delivery of anti-cancer drugs to treat brain tumors in children. Thu, 02 Mar 2023 11:41:49 EST //www.koonmotors.com/releases/2023/03/230302114149.htm Head injuries could be a risk factor for developing brain cancer //www.koonmotors.com/releases/2023/02/230224135003.htm Previous studies have suggested a possible link between head injury and increased rates of brain tumors but evidence has been limited and often inconclusive. A team has now identified a possible mechanism to explain this link, implicating genetic mutations acting in concert with brain tissue inflammation to change the behavior of cells, making them more likely to become cancerous. Although this study was largely carried out in mice, it suggests that it would be important to explore the relevance of these findings to human gliomas. Fri, 24 Feb 2023 13:50:03 EST //www.koonmotors.com/releases/2023/02/230224135003.htm How sound waves trigger immune responses to cancer in mice //www.koonmotors.com/releases/2023/01/230131130948.htm When noninvasive sound waves break apart tumors, they trigger an immune response in mice. By breaking down the cell wall 'cloak,' the treatment exposes cancer cell markers that had previously been hidden from the body's defenses, researchers have shown. Tue, 31 Jan 2023 13:09:48 EST //www.koonmotors.com/releases/2023/01/230131130948.htm CAR T cell therapy may eliminate tumor cells missed by surgery //www.koonmotors.com/releases/2023/01/230111150754.htm CAR T cell therapy may enhance the effectiveness surgery for of solid tumors, according to a preclinical study. Wed, 11 Jan 2023 15:07:54 EST //www.koonmotors.com/releases/2023/01/230111150754.htm Scientists develop a cancer vaccine to simultaneously kill and prevent brain cancer //www.koonmotors.com/releases/2023/01/230104154302.htm Investigators have developed a new cell therapy approach to eliminate established tumors and induce long-term immunity, training the immune system so that it can prevent cancer from recurring. Dual-action cell therapy engineered to eliminate established tumors and train the immune system to eradicate primary tumor and prevent cancer's recurrence. Wed, 04 Jan 2023 15:43:02 EST //www.koonmotors.com/releases/2023/01/230104154302.htm First test of anti-cancer agent PAC-1 in human clinical trials shows promise //www.koonmotors.com/releases/2022/12/221222123115.htm A phase I clinical trial of PAC-1, a drug that spurs programmed cell death in cancer cells, found only minor side effects in patients with end-stage cancers. The drug stalled the growth of tumors in the five people in the trial with neuroendocrine cancers and reduced tumor size in two of those patients. It also showed some therapeutic activity against sarcomas, scientists and clinicians report. Thu, 22 Dec 2022 12:31:15 EST //www.koonmotors.com/releases/2022/12/221222123115.htm 外成的tics breaks into the clinical practice of cancer //www.koonmotors.com/releases/2022/12/221222101019.htm Researchers describe the impact of epigenetics on cancer treatment and how it has become a crucial tool to improve early detection, predict disease progression and become a target for new treatments. Thu, 22 Dec 2022 10:10:19 EST //www.koonmotors.com/releases/2022/12/221222101019.htm Cracking the mystery behind a deadly brain cancer //www.koonmotors.com/releases/2022/12/221221121243.htm Glioblastoma is a deadly brain cancer with a grim prognosis. Unlike most cancers, it still grows in the presence of the P53 protein. For decades, scientists have been unable to crack the case . . . until now. Scientists have discovered a protein known as BRD8 has gone rogue in glioblastoma, crippling P53. The finding could help turn this deadly cancer into a treatable disease. Wed, 21 Dec 2022 12:12:43 EST //www.koonmotors.com/releases/2022/12/221221121243.htm Single-cell 'atlas' reveals origin of an aggressive brain tumor //www.koonmotors.com/releases/2022/11/221130151550.htm Data from a new fetal brain atlas has helped a science team discover a collection of progenitor cells that give rise to aggressive 'group 3' medulloblastomas. Findings include identifying two genes that may serve as treatment targets. Mice with these tumors lived longer when bred to express reduced activity of these genes. Wed, 30 Nov 2022 15:15:50 EST //www.koonmotors.com/releases/2022/11/221130151550.htm Hunting brain cancer cells //www.koonmotors.com/releases/2022/11/221129112914.htm 了解癌细胞从健康发展brain cells and evade treatment could open up potential new drug therapies for glioblastomas, one of the most common and lethal brain cancers, new research has revealed. By bringing together neuroscience and oncology, the team is hopeful of finding a new method to treat the deadly disease. Tue, 29 Nov 2022 11:29:14 EST //www.koonmotors.com/releases/2022/11/221129112914.htm Unraveling the biology behind aggressive pediatric brain tumor reveals potential new treatment avenue //www.koonmotors.com/releases/2022/11/221115133203.htm Researchers have identified a novel treatment approach to an aggressive type of pediatric brain cancer, using therapies already approved to treat cancer. The team developed a mouse model of pediatric glioma with a histone mutation called H3.3-G34, which allowed them to study the tumor's biology in the presence of a functional immune system, revealing a promising outlook for long-term survival. Tue, 15 Nov 2022 13:32:03 EST //www.koonmotors.com/releases/2022/11/221115133203.htm Researchers pinpoint potential treatment for lethal childhood cancer //www.koonmotors.com/releases/2022/11/221110114240.htm Researchers discovered that by blocking the production of an enzyme called DHODH, they were able to halt the growth of MYC gene-amplified medulloblastoma in mouse models, the most aggressive subtype of this cancer. Thu, 10 Nov 2022 11:42:40 EST //www.koonmotors.com/releases/2022/11/221110114240.htm Making glioblastoma more vulnerable to treatment //www.koonmotors.com/releases/2022/11/221101100733.htm In the tough war against glioblastoma, scientists are taking a cue from viruses on how to make the aggressive cancer more vulnerable to treatment. Their target is SAMHD1, a protein which can protect us from viral infections by destroying an essential building block of DNA that viruses and cancer need to replicate. Tue, 01 Nov 2022 10:07:33 EDT //www.koonmotors.com/releases/2022/11/221101100733.htm Researchers identify a gene as a potential target in treatment-resistant brain cancer glioblastoma multiforme //www.koonmotors.com/releases/2022/10/221019172139.htm Research led by doctors and scientists have identified a gene that may provide a therapeutic target for the deadly, treatment-resistant brain cancer glioblastoma multiforme (GBM). Wed, 19 Oct 2022 17:21:39 EDT //www.koonmotors.com/releases/2022/10/221019172139.htm Scientists are one step closer to stopping drug-resistant tumors from growing //www.koonmotors.com/releases/2022/10/221011183854.htm Researchers have solved a long-standing mystery about how a cancer-promoting protein causes drug-resistant tumors to grow. They hope the discovery leads to more effective cancer drugs. Medical researchers explain how this new science is closing the gap in understanding brain and skin tumors and how to combat them. Tue, 11 Oct 2022 18:38:54 EDT //www.koonmotors.com/releases/2022/10/221011183854.htm Critical information about the size and growth speed of gliomas //www.koonmotors.com/releases/2022/10/221007190616.htm An important new clue for preventing and treating brain tumors known as gliomas has been identified. The study provides a rare window into the biological changes behind glioma development. Fri, 07 Oct 2022 19:06:16 EDT //www.koonmotors.com/releases/2022/10/221007190616.htm Scientists identify promising therapeutic target for incurable brain cancer //www.koonmotors.com/releases/2022/10/221005141740.htm Researchers have discovered a cellular partnership that drives the growth of deadly brain tumors and could potentially serve as a novel target for disease treatment. A new study has uncovered a previously unknown genetic process that could inform the development of novel treatment options for GBM. Wed, 05 Oct 2022 14:17:40 EDT //www.koonmotors.com/releases/2022/10/221005141740.htm Biosensor detects brain tumors with less than a drop of blood //www.koonmotors.com/releases/2022/09/220928094753.htm Despite significant advances, mortality from brain tumors remains high with five-year survival rates of 36%. More accurate diagnoses might improve the situation, but tissue biopsies are invasive and can miss important information about a tumor's make-up. Imaging-based methods, meanwhile, do not offer sufficient sensitivity and resolution. Now, researchers have developed a biosensor that could help physicians precisely diagnose brain cancer from a minute blood sample. Wed, 28 Sep 2022 09:47:53 EDT //www.koonmotors.com/releases/2022/09/220928094753.htm New method eradicates deadly brain tumors by 'starving' them of energy source //www.koonmotors.com/releases/2022/09/220901135922.htm In a new study, researchers report that they effectively eradicated glioblastoma, a highly lethal type of brain cancer. The researchers achieved the outcome using a method they developed based on their discovery of two critical mechanisms in the brain that support tumor growth and survival: one protects cancer cells from the immune system, while the other supplies the energy required for rapid tumor growth. The work found that both mechanisms are controlled by brain cells called astrocytes, and in their absence, the tumor cells die and are eliminated. Thu, 01 Sep 2022 13:59:22 EDT //www.koonmotors.com/releases/2022/09/220901135922.htm Understanding why deadly brain cancer comes back //www.koonmotors.com/releases/2022/08/220822130441.htm Brain tumors may create interactions that hide them from the body's defenses. They can adapt to treatment by recruiting help from nearby healthy tissue. These interactions could be why these deadly cancers recur in almost all cases. Mon, 22 Aug 2022 13:04:41 EDT //www.koonmotors.com/releases/2022/08/220822130441.htm Research discovery may help diagnose and treat cancer and brain disorders //www.koonmotors.com/releases/2022/08/220809194903.htm Researchers have revealed how the pathway of an identified protein could lead to early diagnosis and targeted treatment for several cancers and brain disorders. Tue, 09 Aug 2022 19:49:03 EDT //www.koonmotors.com/releases/2022/08/220809194903.htm Scientists identify pathway to curb spread of brain cancer //www.koonmotors.com/releases/2022/08/220809194854.htm Researchers have identified a molecular pathway responsible for the spread of glioblastoma to surrounding tissue in the brain, as well as an existing drug that curbed tumor growth in animal models. The findings have led to a clinical trial that could offer new hope to patients with glioblastoma, the most common form of brain cancer in adults that kills hundreds of thousands of people worldwide each year. Tue, 09 Aug 2022 19:48:54 EDT //www.koonmotors.com/releases/2022/08/220809194854.htm 3D model of brain tumor environment could aid personalized treatment //www.koonmotors.com/releases/2022/08/220801181021.htm Scientists have developed a novel 3D tissue-engineered model of the glioblastoma tumor microenvironment that can be used to learn why the tumors return and what treatments will be most effective at eradicating them -- right down to a patient-specific level. Mon, 01 Aug 2022 18:10:21 EDT //www.koonmotors.com/releases/2022/08/220801181021.htm Gene that causes deadliest brain tumor also causes childhood cancers //www.koonmotors.com/releases/2022/07/220728134048.htm A gene that researchers discovered is responsible for the deadliest type of brain tumor is also responsible for two forms of childhood cancer, the scientists have found. The discovery may open the door to the first targeted treatments for two types of rhabdomyosarcoma, a cancer of the soft tissue that primarily strikes young children. Thu, 28 Jul 2022 13:40:48 EDT //www.koonmotors.com/releases/2022/07/220728134048.htm New insights into melanoma brain metastases //www.koonmotors.com/releases/2022/07/220715205758.htm Cancer researchers have completed one of the most comprehensive studies of the cells inside melanoma brain metastases. Fri, 15 Jul 2022 20:57:58 EDT //www.koonmotors.com/releases/2022/07/220715205758.htm Activating STING could make brain tumors more susceptible to treatment //www.koonmotors.com/releases/2022/07/220711095136.htm Immunotherapy has revolutionized treatment for many forms of cancer, but glioblastoma multiforme (GBM), the most common and deadly form of brain cancer, has remained untouched. GBM tumors are sometimes referred to as 'cold' -- that is, the immune system has a difficult time detecting and targeting them, allowing tumor cells to continue to grow unchecked, even with the advent of immunotherapy drugs. Mon, 11 Jul 2022 09:51:36 EDT //www.koonmotors.com/releases/2022/07/220711095136.htm Dynamic cells linked to brain tumor growth and recurrence //www.koonmotors.com/releases/2022/06/220628170137.htm Researchers have discovered that aggressive tumors contain highly active cells that move throughout tissue in complicated patterns. What's more, the accumulations of these elongated, spindle-like cells found throughout the tumor, coined 'oncostreams,' serve as the basis for cancerous cells' behavior, determining how tumors grow and invade normal tissue. Tue, 28 Jun 2022 17:01:37 EDT //www.koonmotors.com/releases/2022/06/220628170137.htm Biomarkers found that could be drug targets against a deadly form of brain cancer //www.koonmotors.com/releases/2022/06/220622141922.htm Biomarkers that could be targets for novel drugs to treat glioblastoma brain tumors have been identified, providing hope for a cancer that is highly lethal. This new finding provides early evidence that there may be a benefit in targeting specific alterations in cancer cells with newer agents once a patient's tumor becomes resistant to temozolomide. Wed, 22 Jun 2022 14:19:22 EDT //www.koonmotors.com/releases/2022/06/220622141922.htm The interferon gamma receptor pathway is necessary for CAR T-cell mediated killing in solid tumors //www.koonmotors.com/releases/2022/06/220609131946.htm Researchers have discovered that the interferon gamma receptor (IFNgR) signaling pathway is critical for susceptibility of glioblastoma tumors to killing by CAR T-cell immunotherapy. Thu, 09 Jun 2022 13:19:46 EDT //www.koonmotors.com/releases/2022/06/220609131946.htm Recurring brain tumors shaped by genetic evolution and microenvironment //www.koonmotors.com/releases/2022/06/220609131858.htm Researchers have discovered that infiltrating gliomas, a common brain and spinal cord tumor, are shaped by their genetic evolution and microenvironment, a finding that could lead to more targeted treatments. Thu, 09 Jun 2022 13:18:58 EDT //www.koonmotors.com/releases/2022/06/220609131858.htm A nanoparticle and inhibitor trigger the immune system, outsmarting brain cancer //www.koonmotors.com/releases/2022/05/220526095557.htm Scientists have fabricated a nanoparticle to deliver an inhibitor to brain tumor in mouse models, where the drug successfully turned on the immune system to eliminate the cancer. The process also triggered immune memory so that a reintroduced tumor was eliminated--a sign that this potential new approach could not only treat brain tumors but prevent or delay recurrences. Thu, 26 May 2022 09:55:57 EDT //www.koonmotors.com/releases/2022/05/220526095557.htm Scientists develop 'off the shelf' engineered stem cells to treat aggressive brain cancer //www.koonmotors.com/releases/2022/05/220519085428.htm Investigators have devised a novel therapeutic method for treating glioblastomas post-surgery by using stem cells taken from healthy donors engineered to attack GBM-specific tumor cells. This strategy demonstrated profound efficacy in preclinical models of GBM, with 100 percent of mice living over 90 days after treatment. Thu, 19 May 2022 08:54:28 EDT //www.koonmotors.com/releases/2022/05/220519085428.htm Key protein identified for brain stem cell longevity //www.koonmotors.com/releases/2022/05/220511123505.htm 首次发现的受体for insulin action, that also is located on the neural stem cells found deep in the brains of mice, is pivotal for brain stem cell longevity, according to a new study, a finding that has important implications for brain health and future therapies for brain disorders. Wed, 11 May 2022 12:35:05 EDT //www.koonmotors.com/releases/2022/05/220511123505.htm Novel approach could lead to treatment of devastating brain tumors //www.koonmotors.com/releases/2022/05/220509100942.htm Findings from a seven-year research project suggests that there could be a new approach to treating one of the most common and devasting forms of brain cancer in adults -- Glioblastoma Multiforme (GBM). Mon, 09 May 2022 10:09:42 EDT //www.koonmotors.com/releases/2022/05/220509100942.htm AURORA study identifies molecular features tied to breast cancer tumor spread //www.koonmotors.com/releases/2022/04/220411184333.htm 研究微环境中的差异that surround cancer cells in primary tumors versus sites where the tumor metastasized, researchers have identified molecular features responsible for the development and progression of metastatic breast cancer. They discovered genetic changes that led to lower levels of immune cells being able to infiltrate and attack tumor cells, which were more common at metastatic sites. Mon, 11 Apr 2022 18:43:33 EDT //www.koonmotors.com/releases/2022/04/220411184333.htm Researchers identify an immunotherapy target to combat glioblastomas //www.koonmotors.com/releases/2022/04/220405171754.htm Researchers have identified the genetic and molecular fingerprints of different cancer and immune cells in glioblastoma, the deadliest and most common type of brain cancer in adults. Their in-depth molecular analysis of over 200,000 single cells revealed a protein that could be a potential therapeutic target for restoring antitumor action of immune cells toward glioblastomas that have otherwise tricked the immune system into protecting it. Tue, 05 Apr 2022 17:17:54 EDT //www.koonmotors.com/releases/2022/04/220405171754.htm Immunotherapy delays disease progression of high-grade meningiomas //www.koonmotors.com/releases/2022/03/220321115858.htm Meningiomas are the most common primary tumors of the central nervous system. They are treated with surgery and radiation, but drug therapy is usually not effective against these tumors of the brain and spinal cord membranes. The immune checkpoint inhibitor pembrolizumab (Keytruda) showed efficacy against high-grade meningiomas in a clinical trial. Mon, 21 Mar 2022 11:58:58 EDT //www.koonmotors.com/releases/2022/03/220321115858.htm Youngest brain tumor patients have significantly poorer outcomes than older pediatric patients //www.koonmotors.com/releases/2022/03/220318161427.htm A researcher has found, through extensive data analysis, that the youngest patients with brain tumors -- those ages birth to 3 months -- have about half the five-year survival rate as children ages 1 to 19. Fri, 18 Mar 2022 16:14:27 EDT //www.koonmotors.com/releases/2022/03/220318161427.htm Treating cancer with light-sensitive nanoscale biomaterials //www.koonmotors.com/releases/2022/03/220315112957.htm Treating cancer and other diseases with laser light is not currently considered routine, but new approaches using nanoparticles show some promise in improving existing techniques. Researchers review the status of the field and by combining photothermal therapy or photodynamic therapy with nanomaterials, they have been able to apply these types of phototherapies while also delivering drugs to sites in the body that are otherwise inaccessible. It is also possible to combine PTT and PDT into a single treatment, creating an even more powerful treatment method. Tue, 15 Mar 2022 11:29:57 EDT //www.koonmotors.com/releases/2022/03/220315112957.htm Immune cells leave fingerprints on tumors metastasized to the brain offering clues to future therapies //www.koonmotors.com/releases/2022/02/220208113943.htm Using data from over 100,000 malignant and non-malignant cells from 15 human brain metastases, researchers have revealed two functional archetypes of metastatic cells across 7 different types of brain tumors, each containing both immune and non-immune cell types. Their findings provide a potential roadmap for metastatic tumor formation that could be used to design therapies to improve the treatment of metastasized patients. Tue, 08 Feb 2022 11:39:43 EST //www.koonmotors.com/releases/2022/02/220208113943.htm Burst of radiation and vesicles-based immunotherapy suppress brain cancer growth //www.koonmotors.com/releases/2022/01/220131132804.htm The priming of glioblastoma with a burst of radiation increased dramatically the uptake of extracellular vesicles-based immunotherapy by the tumor and the surrounding microenvironment, halting tumor growth, inducing anti-tumor immunity, and prolonging survival in animal models. In glioblastomas primed with radiation, extracellular vesicles allowed the immunotherapy to cross the blood-brain barrier, recruiting immune cells to the tumor site and reversing the expression of PD-L1, the protein responsible for immunosuppression of the larger tumor environment. Mon, 31 Jan 2022 13:28:04 EST //www.koonmotors.com/releases/2022/01/220131132804.htm Researchers discover new way to target secondary breast cancer that has spread to the brain //www.koonmotors.com/releases/2022/01/220128100747.htm A study has revealed a potential new way to treat secondary breast cancer that has spread to the brain, using existing drugs. Fri, 28 Jan 2022 10:07:47 EST //www.koonmotors.com/releases/2022/01/220128100747.htm Chemotherapy’s effectiveness may vary with time of day //www.koonmotors.com/releases/2022/01/220126122410.htm New research suggests that chemotherapy could better target brain tumors in mouse models when it was administered at night instead of during the day. That's because the blood-brain barrier was more likely to allow the chemotherapy to pass through it at night. The findings highlight the importance of this area of research in humans, and one day, they could help to improve outcomes in patients with brain tumors. Wed, 26 Jan 2022 12:24:10 EST //www.koonmotors.com/releases/2022/01/220126122410.htm