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Prenatal and early life exposure to multiple air pollutants increases odds of toddler allergies

Early exposure to candles, cats and environmental tobacco smoke showed greatest impact

Date:
December 5, 2019
Source:
美国过敏、哮喘和Immunology
Summary:
新的一篇文章展示了一个重要的元素een multiple prenatal and early life exposures to indoor pollutants and the degree of allergic sensitivity in 2-year-olds.
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A new article inAnnals of Allergy, Asthma and Immunology, the scientific journal of the American College of Allergy, Asthma and Immunology (ACAAI) shows a significant association between multiple prenatal and early life exposures to indoor pollutants and the degree of allergic sensitivity in 2-year-olds.

"Because most children are exposed to more than one pollutant or allergen, we examined the relationship between multiple exposures and allergic sensitizations at 2 years of age," says Mallory Gallant, MSc, lead author of the study. "We examined exposure to dogs, cats, air fresheners, candles, mold, environmental tobacco smoke (ETS) and carpet, all of which have been associated with childhood allergies. Of the exposures we measured, prenatal exposure to candles, 6-month exposure to cats and 2-year exposure to ETS significantly increased the chance of a positive skin prick test (SPT) at 2 years of age."

108 mother-child pairs were followed from birth to 2 years of age. Exposure to air fresheners, candles, mold, cats, dogs, carpet and environmental tobacco smoke (ETS) during the prenatal, 6-month, 1-year, and 2-year timepoints were obtained. A SPT was performed on both the mother and the 2-year-old child to measure allergic sensitivity. Allergic sensitization means that a person has had (or may have had given the possibilities for false positives) an allergic type immune response to a substance. But it does not necessarily mean that the substance causes them problems.

"The increase in the average amount of time indoors means there is an increased risk of harmful health outcomes related to exposure to indoor air pollutants," says allergist Anne K. Ellis, MD, study author, and member of the ACAAI Environmental Allergy Committee. "Additionally, children breathe more frequently per minute than adults, and mostly breathe through their mouths. These differences could allow for air pollutants to penetrate more deeply into the lungs and at higher concentrations, making children more vulnerable to air pollutants."

Another goal of the study was to evaluate the effect of multiple exposures on allergic outcomes at 2 years of age. The study found that children with a positive SPT at 2 years of age had significantly more exposures prenatally, at the 1-year and 2-year time points compared to children with a negative SPT. As the number of indoor air polluting exposures increased, the percentage of children with a positive SPT increased. Dr. Ellis says, "When considered together, the findings suggest that the effect of multiple exposures may contribute more to allergy development than one single exposure."

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Story Source:

Materialsprovided by美国过敏、哮喘和Immunology.注意:内容可能被编辑风格d length.


Journal Reference:

  1. Mallory J. Gallant, Anne K. Ellis.Prenatal and early life exposure to indoor air-polluting factors and allergic sensitization at 2 years of age.Annals of Allergy, Asthma & Immunology, 2019; DOI:10.1016/j.anai.2019.11.019

Cite This Page:

美国过敏、哮喘和Immunology. "Prenatal and early life exposure to multiple air pollutants increases odds of toddler allergies: Early exposure to candles, cats and environmental tobacco smoke showed greatest impact." ScienceDaily. ScienceDaily, 5 December 2019. .
美国过敏、哮喘和Immunology. (2019, December 5). Prenatal and early life exposure to multiple air pollutants increases odds of toddler allergies: Early exposure to candles, cats and environmental tobacco smoke showed greatest impact.ScienceDaily. Retrieved June 27, 2023 from www.koonmotors.com/releases/2019/12/191205130554.htm
美国过敏、哮喘和Immunology. "Prenatal and early life exposure to multiple air pollutants increases odds of toddler allergies: Early exposure to candles, cats and environmental tobacco smoke showed greatest impact." ScienceDaily. www.koonmotors.com/releases/2019/12/191205130554.htm (accessed June 27, 2023).

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