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从研究机构

Understanding C. auris transmission with the healthcare environment

Date:
June 23, 2019
Source:
American Society for Microbiology
Summary:
Researchers have now shown that patients who are heavily colonized with Candida auris on their skin can shed the fungus and contaminate their surroundings. This finding provides an explanation for the extensive contamination that often occurs in healthcare facilities with C. auris outbreaks. These results can help inform infection control efforts.
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Researchers have now shown that patients who are heavily colonized withCandida auris在他们的skin can shed the fungus and contaminate their surroundings. This finding provides an explanation for the extensive contamination that often occurs in healthcare facilities withC. aurisoutbreaks. These results can help inform infection control efforts. The research is presented at ASM Microbe, the annual meeting of the American Society for Microbiology.

C. aurisis an emerging fungal pathogen that can cause large outbreaks in healthcare facilities. Understanding howC. aurisspreads in healthcare facilities is essential for infection control. BecauseC. auriscan be present on the skin without causing symptoms, it has been hypothesized that the spread ofC. aurisoccurs as patients naturally shed their skin cells. This process could lead to substantial contamination of the surrounding environment and therefore increase chances of transmittingC. auris.

To test this hypothesis, the researchers developed methods to countC. aurisin samples collected from patients' skin and their rooms. We found that patients can have very high concentrations ofC. auris在他们的skin, and higher levels ofC. auris在他们的skin were correlated with higher levels ofC. aurison the patient's bed.

"This finding supported our hypothesis that patients are actively sheddingC. auriscells into their environment," said Joe Sexton, ORISE post-doctoral fellow in the Mycotic Diseases Branch at the Centers for Disease Control and Prevention, who designed and led the study. The researchers were able to culture liveC. aurisfrom the beds of all patients who tested positive, and even beds that were previously, but no longer, occupied by patients withC. auris.

"These results should be considered in developing more effective strategies for infection control efforts during aC. aurisoutbreak," said Dr. Sexton.

病人和环境样本processed in the Mycotic Diseases Branch laboratory in Atlanta by Joe Sexton, Meghan Bentz, and Rory Welsh and Anastasia Litvintseva, who served as a principal investigator (PI). These samples were collected by the City of Chicago's Public Health Department led by Massimo Pacilli.

Additional groups within CDC also supported this work including the Department of Scientific Resources and the Division of Healthcare Quality and Promotion, and the Oak Ridge Institute for Science and Education. This work will be presented at American Society of Microbiology (ASM) Microbe 2019 conference in San Francisco, California (June 20-24, 2019).

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Cite This Page:

American Society for Microbiology. "Understanding C. auris transmission with the healthcare environment." ScienceDaily. ScienceDaily, 23 June 2019. .
American Society for Microbiology. (2019, June 23). Understanding C. auris transmission with the healthcare environment.ScienceDaily. Retrieved June 26, 2023 from www.koonmotors.com/releases/2019/06/190623143102.htm
American Society for Microbiology. "Understanding C. auris transmission with the healthcare environment." ScienceDaily. www.koonmotors.com/releases/2019/06/190623143102.htm (accessed June 26, 2023).

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