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Virtual brain could aid surgical planning

Personalized brain models could improve surgical planning and outcomes

Date:
May 29, 2018
Source:
Society for Neuroscience
Summary:
Researchers have simulated neural activity based on the unique structural architecture of individual brain tumor patients using a platform called The Virtual Brain. The findings are a first step toward creating personalized brain models that could be used to predict the effects of tumors and consequent surgery on brain function.
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FULL STORY

Researchers have simulated neural activity based on the unique structural architecture of individual brain tumor patients using a platform called The Virtual Brain. The findings, reported ineNeuro, are a first step toward creating personalized brain models that could be used to predict the effects of tumors and consequent surgery on brain function.

Brain surgery is delicate work that requires careful planning to maximally remove a tumor while leaving the surrounding tissue intact. Common techniques such as functional magnetic resonance imaging (fMRI) are used to map out a surgical strategy by identifying important functional areas close to the tumor. These approaches are limited, however, in their ability to predict post-surgical outcome because of the complex dynamics of the brain and the widespread modifications of brain activity.

Using the open-source software The Virtual Brain, Hannelore Aerts and a team led by Daniele Marinazzo modeled 25 individual brain networks of brain tumor patients and 11 of their partners as a control group. The researchers demonstrated that these individualized models can accurately predict the effects of the tumors on brain connectivity. This result opens the possibility of integrating neuroimaging data with virtual brain modeling to improve surgical planning and outcomes.

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Materials provided bySociety for Neuroscience.Note: Content may be edited for style and length.


Journal Reference:

  1. Hannelore Aerts, Michael Schirner, Ben Jeurissen, Dirk Van Roost, Eric Achten, Petra Ritter, Daniele Marinazzo.Modeling Brain Dynamics in Brain Tumor Patients Using the Virtual Brain.eneuro, 2018; ENEURO.0083-18.2018 DOI:10.1523/ENEURO.0083-18.2018

Cite This Page:

Society for Neuroscience. "Virtual brain could aid surgical planning: Personalized brain models could improve surgical planning and outcomes." ScienceDaily. ScienceDaily, 29 May 2018. .
Society for Neuroscience. (2018, May 29). Virtual brain could aid surgical planning: Personalized brain models could improve surgical planning and outcomes.ScienceDaily. Retrieved June 18, 2023 from www.koonmotors.com/releases/2018/05/180529132117.htm
Society for Neuroscience. "Virtual brain could aid surgical planning: Personalized brain models could improve surgical planning and outcomes." ScienceDaily. www.koonmotors.com/releases/2018/05/180529132117.htm (accessed June 18, 2023).

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