//www.koonmotors.com/news/plants_animals/biotechnology_and_bioengineering/ Biotechnology and bioengineering research news. en-us Sun, 10 Sep 2023 21:22:32 EDT Sun, 10 Sep 2023 21:22:32 EDT 60 //www.koonmotors.com/images/scidaily-logo-rss.png//www.koonmotors.com/news/plants_animals/biotechnology_and_bioengineering/ For more science news, visit ScienceDaily. //www.koonmotors.com/releases/2023/09/230905124850.htm A 'living material,' made of a natural polymer combined with genetically engineered bacteria, could offer a sustainable and eco-friendly solution to clean pollutants from water. Researchers developed their living material using a seaweed-based polymer and bacteria that have been programmed to produce an enzyme that transforms various organic pollutants into harmless compounds. In tests, heir material decontaminated water solutions tainted with a pollutant from textile manufacturing: indigo carmine, a blue dye that is used to color denim. Tue, 05 Sep 2023 12:48:50 EDT //www.koonmotors.com/releases/2023/09/230905124850.htm //www.koonmotors.com/releases/2023/08/230824111925.htm Researchers have discovered a novel approach for engrafting engineered cells into injured lung tissue. These findings may lead to new ways for treating lung diseases, such as emphysema, pulmonary fibrosis and COVID-19. The two studies describe the methodologies for engineering lung stem cells and transplanting them into injured experimental lungs without immunosuppression. Thu, 24 Aug 2023 11:19:25 EDT //www.koonmotors.com/releases/2023/08/230824111925.htm //www.koonmotors.com/releases/2023/08/230816114121.htm A new method allows large quantities of muscle stem cells to be safely obtained in cell culture. This provides a potential for treating patients with muscle diseases -- and for those who would like to eat meat, but don't want to kill animals. Wed, 16 Aug 2023 11:41:21 EDT //www.koonmotors.com/releases/2023/08/230816114121.htm //www.koonmotors.com/releases/2023/08/230810140813.htm Creating new technologically advanced sensors, scientists have engineered bacteria that detect the presence of tumor DNA in live organisms. Their innovation could pave the way to new biosensors capable of identifying various infections, cancers and other diseases. Thu, 10 Aug 2023 14:08:13 EDT //www.koonmotors.com/releases/2023/08/230810140813.htm //www.koonmotors.com/releases/2023/07/230720124918.htm Climate change is affecting the types of plant varieties we can cultivate, as well as how and where we can do so. A new collection of articles in the open access journal PLOS Biology explores the twin challenges of engineering plants for resilience to climate change and enhancing their carbon-capture potential. Thu, 20 Jul 2023 12:49:18 EDT //www.koonmotors.com/releases/2023/07/230720124918.htm //www.koonmotors.com/releases/2023/06/230621164758.htm For the first time, researchers have developed a genome-scale way to map the regulatory role of transcription factors, proteins that play a key role in gene expression and determining a plant's physiological traits. Their work reveals unprecedented insights into gene regulatory networks and identifies a new library of DNA parts that can be used to optimize plants for bioenergy and agriculture. Wed, 21 Jun 2023 16:47:58 EDT //www.koonmotors.com/releases/2023/06/230621164758.htm //www.koonmotors.com/releases/2023/06/230612200341.htm Researchers have now used a gene-drive system to suppress an important agricultural pest. Mon, 12 Jun 2023 20:03:41 EDT //www.koonmotors.com/releases/2023/06/230612200341.htm //www.koonmotors.com/releases/2023/05/230522131345.htm Scientists have developed a groundbreaking new technique for engineering biosensors that respond sensitively to specific biomolecules, enhancing cell migration and targeting in cancer treatment. The findings could lead to more precise control over cellular processes for a wide range of therapeutic applications. Mon, 22 May 2023 13:13:45 EDT //www.koonmotors.com/releases/2023/05/230522131345.htm //www.koonmotors.com/releases/2023/05/230509122044.htm A new drug candidate targeting E. coli in the gut is in phase 1 clinical trials. According to a new paper it may improve the well-being of blood cancer patients and reduce their mortality rate from E. coli infections. Tue, 09 May 2023 12:20:44 EDT //www.koonmotors.com/releases/2023/05/230509122044.htm //www.koonmotors.com/releases/2023/05/230503085331.htm A team of researchers develops stem cell adhesive for arthritis treatment using mussel adhesion protein and hyaluronic acid. Wed, 03 May 2023 08:53:31 EDT //www.koonmotors.com/releases/2023/05/230503085331.htm //www.koonmotors.com/releases/2023/04/230427173454.htm Researchers have developed a biosynthetic 'clock' that keeps cells from reaching normal levels of deterioration related to aging. They engineered a gene oscillator that switches between the two normal paths of aging, slowing cell degeneration and setting a record for life extension. Thu, 27 Apr 2023 17:34:54 EDT //www.koonmotors.com/releases/2023/04/230427173454.htm //www.koonmotors.com/releases/2023/04/230420171633.htm Engineers developed a method to create synthetic spider silk at high yields while retaining strength and toughness using mussel foot proteins. Thu, 20 Apr 2023 17:16:33 EDT //www.koonmotors.com/releases/2023/04/230420171633.htm //www.koonmotors.com/releases/2023/04/230418101447.htm Scientists can now use light to activate protein functions both inside and outside of living cells. The new method, called light-activated SpyLigation, can turn on proteins that are normally off to allow researchers to study and control them in more detail. This technology has potential uses in tissue engineering, regenerative medicine, and understanding how the body works. The scientists applied their new method to control the glow of a green fluorescent protein derived from Japanese eel muscle. Tue, 18 Apr 2023 10:14:47 EDT //www.koonmotors.com/releases/2023/04/230418101447.htm //www.koonmotors.com/releases/2023/04/230411105843.htm A probiotic treatment reduced the negative effects of alcohol consumption in mice. Tue, 11 Apr 2023 10:58:43 EDT //www.koonmotors.com/releases/2023/04/230411105843.htm //www.koonmotors.com/releases/2023/04/230410000338.htm Tobacco plants have been engineered to manufacture an alluring perfume of insect sex pheromones, which could be used to confuse would-be pests looking for love and reduce the need for harmful pesticides. Mon, 10 Apr 2023 00:03:38 EDT //www.koonmotors.com/releases/2023/04/230410000338.htm //www.koonmotors.com/releases/2023/03/230315132359.htm In a step forward for genetic engineering and synthetic biology, researchers have modified a strain of Escherichia coli bacteria to be immune to natural viral infections while also minimizing the potential for the bacteria or their modified genes to escape into the wild. Wed, 15 Mar 2023 13:23:59 EDT //www.koonmotors.com/releases/2023/03/230315132359.htm //www.koonmotors.com/releases/2023/02/230222210532.htm 科学家最近宣布的发明一种nanowire 10,000 times thinner than a human hair that can be cheaply grown by common bacteria and tuned to 'smell' a vast array of chemical tracers -- including those given off by people afflicted with a wide range of medical conditions, such as asthma and kidney disease. Thousands of these specially tuned wires, each sniffing out a different chemical, can be layered onto tiny, wearable sensors, allowing healthcare providers an unprecedented tool for monitoring potential health complications. Since these wires are grown by bacteria, they are organic, biodegradable and far greener than any inorganic nanowire. Wed, 22 Feb 2023 21:05:32 EST //www.koonmotors.com/releases/2023/02/230222210532.htm //www.koonmotors.com/releases/2023/02/230222115842.htm Researchers have added components of plant chloroplasts to bacteria. This feat, 50 years in the making, allows them to analyze the proteins in greater detail in order to improve Rubisco, and eventually photosynthesis. Wed, 22 Feb 2023 11:58:42 EST //www.koonmotors.com/releases/2023/02/230222115842.htm //www.koonmotors.com/releases/2023/02/230216172206.htm Metabolic engineering is a field of plant biotechnology that seeks to genetically modify plant metabolic pathways to generate plant varieties with improved health benefits. Recently, scientists engineered potato and tomato plants to express the plant pigment betalain -- found only in Caryophyllales and higher fungi. They found that while betalain-tomatoes conferred anti-inflammatory effects against macrophages and murine colitis, betalain-potatoes showed no such effects. Thu, 16 Feb 2023 17:22:06 EST //www.koonmotors.com/releases/2023/02/230216172206.htm //www.koonmotors.com/releases/2023/01/230119112740.htm Researchers demonstrate that a bacteria can be modified to act as 'living medicine' in the lung. The treatment significantly reduced acute lung infections in mice and doubled their survival rate. It showed no signs of toxicity in the lungs and once the treatment had finished its course, it was cleared by the immune system in a period of four days. The treatment also cleared biofilms that accumulate on the surface of endotracheal tubes used by patients with ventilator-associated pneumonia, which is one of the leading causes of mortality in intensive care units. The study paves the way for researchers to repurpose the bacteria to treat other types of lung diseases such as cancer, asthma or pulmonary fibrosis. Thu, 19 Jan 2023 11:27:40 EST //www.koonmotors.com/releases/2023/01/230119112740.htm //www.koonmotors.com/releases/2023/01/230116112626.htm 减少气孔的数量,大米s them more tolerant to salt water, according to researchers. Mon, 16 Jan 2023 11:26:26 EST //www.koonmotors.com/releases/2023/01/230116112626.htm //www.koonmotors.com/releases/2023/01/230103133731.htm Researchers have shown that zebrafish can provide genetic baz1b clues to the evolution of social behaviors in humans and domesticated species. Tue, 03 Jan 2023 13:37:31 EST //www.koonmotors.com/releases/2023/01/230103133731.htm //www.koonmotors.com/releases/2022/12/221222123133.htm Researchers have shown that changes in gene expression happen almost entirely during the transcription stage while the cells are growing. The researchers have provided a simple quantitative formula linking regulatory control to mRNA and protein levels. Thu, 22 Dec 2022 12:31:33 EST //www.koonmotors.com/releases/2022/12/221222123133.htm //www.koonmotors.com/releases/2022/12/221212140159.htm Researchers have engineered molecules that act like 'cellular glue,' allowing them to direct in precise fashion how cells bond with each other. The discovery represents a major step toward building tissues and organs, a long-sought goal of regenerative medicine. Mon, 12 Dec 2022 14:01:59 EST //www.koonmotors.com/releases/2022/12/221212140159.htm //www.koonmotors.com/releases/2022/12/221209153042.htm During infections, the hematopoietic system switches from normal to emergency mode. This improves the defense against the pathogens. Scientists have now found an epigenetic switch in blood stem cells and progenitor cells of mice that can trigger the switch from one mode to the other. Fri, 09 Dec 2022 15:30:42 EST //www.koonmotors.com/releases/2022/12/221209153042.htm //www.koonmotors.com/releases/2022/12/221206115719.htm At the heart of every CRISPR reaction, whether naturally occurring in bacteria or harnessed by CRIPSR-Cas gene editing technology, is a strong molecular bond of a Cas protein via a guide RNA to its target site on DNA. It's like a nanoscale ski binding. Tue, 06 Dec 2022 11:57:19 EST //www.koonmotors.com/releases/2022/12/221206115719.htm //www.koonmotors.com/releases/2022/11/221130151501.htm Researchers introduced seven proteins, thought to let Spiroplama bacteria swim by switching the direction that their helical bodies spiral, into a strain of synthetic bacterium with minimal genetic information. As a result, they confirmed that the synthetic bacterium named syn3, which is normally spherical, formed a helix that could swim by spiraling. Further investigation revealed that only two of these newly added proteins were required to make syn3 capable of minimal swimming. This swimming synthetic bacterium can be said to be the smallest mobile lifeform genetically, as it contains the fewest number of genes. Wed, 30 Nov 2022 15:15:01 EST //www.koonmotors.com/releases/2022/11/221130151501.htm //www.koonmotors.com/releases/2022/11/221122111439.htm A team of synthetic biologists has recently discovered a way that could increase synthetic mRNA's protein production efficiency by up to 10 times, which means the effectiveness of mRNA vaccines and drugs -- such as those used against cancer, COVID-19 or other genetic diseases, will be greatly boosted with even less dosage of the mRNAs. Tue, 22 Nov 2022 11:14:39 EST //www.koonmotors.com/releases/2022/11/221122111439.htm //www.koonmotors.com/releases/2022/11/221117102723.htm Researchers found that the fungus Metarhizium robertsii removes mercury from the soil around plant roots, and from fresh and saltwater. The researchers also genetically engineered the fungus to amplify its mercury detoxifying effects. This new work suggests Metarhizium could provide an inexpensive and efficient way to protect crops grown in polluted areas and remediate mercury-laden waterways. Thu, 17 Nov 2022 10:27:23 EST //www.koonmotors.com/releases/2022/11/221117102723.htm //www.koonmotors.com/releases/2022/11/221116085942.htm Researchers have genetically engineered a protein to emit the shortest-wavelength fluorescence light reported to date. They did this by optimizing the interactions between the fluorescence center (chromophore) and its surroundings, in a manner that differs from previous reports. The resulting fluorescence emission was bright and stable over a useful range of pH values. This work will aid basic and applied research, such as understanding the behavior of healthy and diseased cells. Wed, 16 Nov 2022 08:59:42 EST //www.koonmotors.com/releases/2022/11/221116085942.htm //www.koonmotors.com/releases/2022/11/221114111041.htm Bringing together concepts from electrical engineering and bioengineering tools, scientists collaborated to produce cells engineered to compute sophisticated functions -- 'biocomputers' of sorts. Researchers worked to create genetic 'devices' designed to perform computations like artificial neural circuits. Mon, 14 Nov 2022 11:10:41 EST //www.koonmotors.com/releases/2022/11/221114111041.htm //www.koonmotors.com/releases/2022/11/221114095315.htm The better we understand cellular processes such as RNA regulation, the better molecular therapies can be developed. Until now, it has been especially difficult to track the regulation of non-coding RNA, which is RNA that is not further converted into proteins. A research team has now developed a minimally invasive reporter system that enables highly sensitive monitoring of RNA production of both coding and non-coding RNA. Mon, 14 Nov 2022 09:53:15 EST //www.koonmotors.com/releases/2022/11/221114095315.htm //www.koonmotors.com/releases/2022/11/221114095300.htm A fluorescent protein makes it possible to follow disease progression in brain diseases such as Alzheimer's, strokes, and depression. That may lead to better insight into diseases and possible new treatments. Mon, 14 Nov 2022 09:53:00 EST //www.koonmotors.com/releases/2022/11/221114095300.htm //www.koonmotors.com/releases/2022/11/221109124301.htm Scientists have successfully bioengineered an important protein in plants to increase the yield of oil from their fruits and seeds -- a holy grail for the global agri-food industry. Their patent-pending method can increase oil content in seeds by 15 to 18 per cent, which is a significant improvement since major oil-producing crops such as soybean, sunflower, rapeseed, and peanut, already have a high percentage of oil in their seeds. This innovation can help the world in its quest for sustainability, helping to reduce the amount of arable land needed for oil-yielding crops while increasing the yield to meet the world's growing demand for vegetable oil. Wed, 09 Nov 2022 12:43:01 EST //www.koonmotors.com/releases/2022/11/221109124301.htm //www.koonmotors.com/releases/2022/11/221101151944.htm Using an approach based on the CRISPR gene-editing system, researchers developed a way to precisely control the amount of a particular protein that is produced in mammalian cells. Tue, 01 Nov 2022 15:19:44 EDT //www.koonmotors.com/releases/2022/11/221101151944.htm //www.koonmotors.com/releases/2022/10/221026122730.htm Controlling gene activity is important for engineering plants for improved bioenergy crops and other applications. This research developed synthetic genes that use Boolean logic gates to achieve specific patterns of gene expression within a plant. The researchers used these gene circuits to redesign the root architecture by tuning the number of root branches. Wed, 26 Oct 2022 12:27:30 EDT //www.koonmotors.com/releases/2022/10/221026122730.htm //www.koonmotors.com/releases/2022/10/221024102909.htm Researchers are working to reveal potential threats to the efficacy of CRISPR/Cas9 gene editing, even when it appears to be working as planned. Mon, 24 Oct 2022 10:29:09 EDT //www.koonmotors.com/releases/2022/10/221024102909.htm //www.koonmotors.com/releases/2022/10/221005132944.htm Synthetic biology strives to achieve robust control of biological processes in order to create designer organisms for a variety of industrial, diagnostic, and therapeutic applications. Researchers have developed RNA origami sponges and CRISPR-based regulators for advanced genetic control of enzymatic pathways in microorganisms to improve production of valuable biochemicals. Wed, 05 Oct 2022 13:29:44 EDT //www.koonmotors.com/releases/2022/10/221005132944.htm //www.koonmotors.com/releases/2022/10/221005111930.htm In the brain of adult mammals neural stem cells ensure that new nerve cells, i.e. neurons, are constantly formed. This process, known as adult neurogenesis, helps mice maintain their sense of smell. A research team recently discovered a second stem cell population in the mouse brain, which is primarily involved in the production of new neurons in the olfactory bulb of adult mice. Wed, 05 Oct 2022 11:19:30 EDT //www.koonmotors.com/releases/2022/10/221005111930.htm //www.koonmotors.com/releases/2022/09/220923090837.htm Bioscientists turn bacteria into self-assembling building blocks. The macroscale engineered living materials they form could be used to soak up targeted contaminants from the environment or as custom catalysts, among many possible applications. Fri, 23 Sep 2022 09:08:37 EDT //www.koonmotors.com/releases/2022/09/220923090837.htm //www.koonmotors.com/releases/2022/09/220920100738.htm The ideal crop plant is tasty and high-yielding while also being resistant to diseases and pests. But if the relevant genes are far apart on a chromosome, some of these positive traits can be lost during breeding. To ensure that positive traits can be passed on together, researchers have used CRISPR/Cas molecular scissors to invert and thus genetically deactivate nine-tenths of a chromosome. The traits coded for on this part of the chromosome become 'invisible' for genetic exchange and can thus be passed on unchanged. Tue, 20 Sep 2022 10:07:38 EDT //www.koonmotors.com/releases/2022/09/220920100738.htm //www.koonmotors.com/releases/2022/09/220914140958.htm Scientists have harnessed the potential of bacteria to help build advanced synthetic cells which mimic real life functionality. Wed, 14 Sep 2022 14:09:58 EDT //www.koonmotors.com/releases/2022/09/220914140958.htm //www.koonmotors.com/releases/2022/09/220908172233.htm A team of interdisciplinary researchers has developed techniques to improve the efficiency of CRISPR-Cas9, the genome editing technique that earned the Nobel Prize in 2020. Thu, 08 Sep 2022 17:22:33 EDT //www.koonmotors.com/releases/2022/09/220908172233.htm //www.koonmotors.com/releases/2022/09/220901151556.htm A Policy Forum article calls for a new approach to regulating genetically engineered (GE) crops, arguing that current approaches for triggering safety testing vary dramatically among countries and generally lack scientific merit -- particularly as advances in crop breeding have blurred the lines between conventional breeding and genetic engineering. Thu, 01 Sep 2022 15:15:56 EDT //www.koonmotors.com/releases/2022/09/220901151556.htm //www.koonmotors.com/releases/2022/09/220901135821.htm Biomedical engineers have demonstrated a microbial community phenomenon that essentially equates to teaching neighbors how to complete necessary tasks by ripping out and sharing part of the brain. The process of horizontal gene transfer allows microbiomes to keep themselves and their environments healthy and could help scientists create robust, bespoke microbial systems for applications ranging from cleaning toxins from the environment to producing biofuel and other consumer products. Thu, 01 Sep 2022 13:58:21 EDT //www.koonmotors.com/releases/2022/09/220901135821.htm //www.koonmotors.com/releases/2022/08/220825164008.htm New research offers insights into a line of CRISPR systems, which could lead to promising antiviral and tissue engineering tools in animal and plants. Thu, 25 Aug 2022 16:40:08 EDT //www.koonmotors.com/releases/2022/08/220825164008.htm //www.koonmotors.com/releases/2022/08/220824225727.htm 乙醇可以帮助植物生存在drough的时期t says a new study. Adding ethanol to soil allows plants, including rice and wheat, to thrive after two weeks without any water. As ethanol is safe, cheap, and widely available, this finding offers a practical way to increase food production all over the world when water is scarce, without the need for costly, time-consuming, and sometimes controversial production of genetically modified plants. Wed, 24 Aug 2022 22:57:27 EDT //www.koonmotors.com/releases/2022/08/220824225727.htm //www.koonmotors.com/releases/2022/08/220804130603.htm Scientists have long tried to introduce genetically engineered bacteria into the gut to treat diseases. In the past, these attempts have focused on engineering common lab strains of E. coli, which cannot compete with the native gut bacteria that are well adapted to their host. Now, a group of researchers successfully engineered E. coli collected from both human and mice gut microbiomes and showed that they have the potential to treat diseases such as diabetes. Thu, 04 Aug 2022 13:06:03 EDT //www.koonmotors.com/releases/2022/08/220804130603.htm //www.koonmotors.com/releases/2022/08/220804130600.htm Researchers generated rat sperm cells inside sterile mice using a technique called blastocyst complementation. Thu, 04 Aug 2022 13:06:00 EDT //www.koonmotors.com/releases/2022/08/220804130600.htm //www.koonmotors.com/releases/2022/08/220801102934.htm The researchers identified a library of synthetic polymers and screened them for their ability to induce biofilm formation in E. coli, a bacterium that is one of the most widely studied micro-organisms, and commonly used in biocatalysis. Mon, 01 Aug 2022 10:29:34 EDT //www.koonmotors.com/releases/2022/08/220801102934.htm //www.koonmotors.com/releases/2022/07/220727110300.htm An international team of researchers has developed a method for altering one class of antibiotics, using microscopic organisms that produce these compounds naturally. Wed, 27 Jul 2022 11:03:00 EDT //www.koonmotors.com/releases/2022/07/220727110300.htm //www.koonmotors.com/releases/2022/07/220718094428.htm Bioengineers used deactivated Cas9 fusion proteins to synthetically control gene expression and reveal new details about natural processes in human cells. Mon, 18 Jul 2022 09:44:28 EDT //www.koonmotors.com/releases/2022/07/220718094428.htm //www.koonmotors.com/releases/2022/07/220711095203.htm The development of DNA-/RNA-based drugs, like COVID-19 vaccines, is exploding. Current methods are costly, but researchers are finding effective and inexpensive method for producing stable, modified DNA sequences for these modern-type drugs. Mon, 11 Jul 2022 09:52:03 EDT //www.koonmotors.com/releases/2022/07/220711095203.htm //www.koonmotors.com/releases/2022/07/220708123638.htm Researchers develop user-friendly software system to optimize biological systems. Fri, 08 Jul 2022 12:36:38 EDT //www.koonmotors.com/releases/2022/07/220708123638.htm //www.koonmotors.com/releases/2022/07/220707141801.htm For more affordable, sustainable drug options than we have today, the medication we take to treat high blood pressure, pain or memory loss may one day come from engineered bacteria, cultured in a vat like yogurt. And thanks to a new bacterial tool, the process of improving drug manufacturing in bacterial cells may be coming sooner than we thought. Thu, 07 Jul 2022 14:18:01 EDT //www.koonmotors.com/releases/2022/07/220707141801.htm //www.koonmotors.com/releases/2022/06/220630142132.htm 研究人员创建人工Hox基因——which plan and direct where cells go to develop tissues or organs -- using new synthetic DNA technology and genomic engineering in stem cells. Their findings confirm how clusters of Hox genes help cells to learn and remember where they are in the body. Thu, 30 Jun 2022 14:21:32 EDT //www.koonmotors.com/releases/2022/06/220630142132.htm //www.koonmotors.com/releases/2022/06/220622113155.htm The deletion of the Wt1 gene during the early stages of the embryonic reproductive organ formation leads to differences in sex development in adult mice, according to a new study. Wed, 22 Jun 2022 11:31:55 EDT //www.koonmotors.com/releases/2022/06/220622113155.htm //www.koonmotors.com/releases/2022/05/220523135016.htm Scientists have developed CRISPR-Combo, a method to edit multiple genes in plants while simultaneously changing the expression of other genes. This new tool will enable genetic engineering combinations that work together to boost functionality and improve breeding of new crops. Mon, 23 May 2022 13:50:16 EDT //www.koonmotors.com/releases/2022/05/220523135016.htm //www.koonmotors.com/releases/2022/05/220512144328.htm Researchers have equipped gut bacteria with data logger functionality as a way of monitoring which genes are active in the bacteria. These microorganisms could one day offer a noninvasive means of diagnosing disease or assessing the impact of a diet on health. Thu, 12 May 2022 14:43:28 EDT //www.koonmotors.com/releases/2022/05/220512144328.htm //www.koonmotors.com/releases/2022/05/220506141148.htm Every species, from bacteria to humans, is capable of regeneration. Regeneration is mediated by the molecular processes that regulate gene expression to control tissue renewal, restoration and growth. Fri, 06 May 2022 14:11:48 EDT //www.koonmotors.com/releases/2022/05/220506141148.htm