Stem Cells News -- ScienceDaily //www.koonmotors.com/news/health_medicine/stem_cells/ Read about today's stem cell research including novel stem cell technology and advances in understanding cancer stem cells. en-us Fri, 08 Sep 2023 22:47:37 EDT Fri, 08 Sep 2023 22:47:37 EDT 60 Stem Cells News -- ScienceDaily //www.koonmotors.com/images/scidaily-logo-rss.png//www.koonmotors.com/news/health_medicine/stem_cells/ For more science news, visit ScienceDaily. Researchers grow embryonic humanized kidneys inside pigs for 28 days //www.koonmotors.com/releases/2023/09/230907130350.htm Researchers have successfully created chimeric embryos containing a combination of human and pig cells. When transferred into surrogate pig mothers, the developing humanized kidneys had normal structure and tubule formation after 28 days. This is the first time that scientists have been able to grow a solid humanized organ inside another species, though previous studies have used similar methods to generate human tissues such as blood or skeletal muscle in pigs. Thu, 07 Sep 2023 13:03:50 EDT //www.koonmotors.com/releases/2023/09/230907130350.htm Expanding the impact of CAR T cell therapy: An immunotherapy strategy against all blood cancers //www.koonmotors.com/releases/2023/08/230831142858.htm A broad new strategy could hold hope for treating virtually all blood cancers with CAR T cell therapy, which is currently approved for five subtypes of blood cancer. Scientists have demonstrated the potential efficacy of this approach a preclinical study. Thu, 31 Aug 2023 14:28:58 EDT //www.koonmotors.com/releases/2023/08/230831142858.htm Promising evidence for sickle cell gene therapy //www.koonmotors.com/releases/2023/08/230830195934.htm A clinical trial has tested a potentially curative stem cell gene therapy for sickle cell disease. The results were promising. Wed, 30 Aug 2023 19:59:34 EDT //www.koonmotors.com/releases/2023/08/230830195934.htm Researchers identify stem cells in the thymus //www.koonmotors.com/releases/2023/08/230830131653.htm Researchers have identified stem cells in the human thymus for the first time. These cells represent a potential new target to understand immune diseases and cancer and how to boost the immune system. Wed, 30 Aug 2023 13:16:53 EDT //www.koonmotors.com/releases/2023/08/230830131653.htm Researchers describe rebuilding, regenerating lung cells //www.koonmotors.com/releases/2023/08/230824111925.htm Researchers have discovered a novel approach for engrafting engineered cells into injured lung tissue. These findings may lead to new ways for treating lung diseases, such as emphysema, pulmonary fibrosis and COVID-19. The two studies describe the methodologies for engineering lung stem cells and transplanting them into injured experimental lungs without immunosuppression. Thu, 24 Aug 2023 11:19:25 EDT //www.koonmotors.com/releases/2023/08/230824111925.htm How TET2 gene deficiency fuels development of acute myeloid leukemia //www.koonmotors.com/releases/2023/08/230817164043.htm Scientists have identified how low levels of the TET2 gene fuel the rapid growth of acute myeloid leukemia in animal models. Thu, 17 Aug 2023 16:40:43 EDT //www.koonmotors.com/releases/2023/08/230817164043.htm With advances in in vitro models, group proposes refined legal definition of an embryo //www.koonmotors.com/releases/2023/08/230817163927.htm Thanks to continuous advances in human stem cell research, studies that make use of embryo models are progressing quickly. This research offers both a scientific and ethical alternative to the use of embryos resulting from fertilized human eggs, and the appropriate ethical guidelines have been developed in parallel with the advances being made. A group of biologists and ethicists suggest additions to the current ethical framework that refine thinking about human embryology using embryo models to maximize benefits to society. Thu, 17 Aug 2023 16:39:27 EDT //www.koonmotors.com/releases/2023/08/230817163927.htm Building muscle in the lab //www.koonmotors.com/releases/2023/08/230816114121.htm 一种新方法允许大量的肌肉stem cells to be safely obtained in cell culture. This provides a potential for treating patients with muscle diseases -- and for those who would like to eat meat, but don't want to kill animals. Wed, 16 Aug 2023 11:41:21 EDT //www.koonmotors.com/releases/2023/08/230816114121.htm Genetically modified neural stem cells show promising therapeutic potential for spinal cord injury //www.koonmotors.com/releases/2023/08/230816114119.htm A research team has recently made a significant advancement in spinal cord injury treatment by using genetically modified human neural stem cells (hNSCs). They found that specifically modulating a gene expression to a certain level in hNSCs can effectively promote the reconstruction of damaged neural circuits and restore locomotor functions, offering great potential for new therapeutic opportunities for patients with spinal cord injury. Wed, 16 Aug 2023 11:41:19 EDT //www.koonmotors.com/releases/2023/08/230816114119.htm Stem-cell derived organoids secrete tooth enamel proteins //www.koonmotors.com/releases/2023/08/230814122258.htm 从干细胞瀑样已经被创建secrete the proteins that form dental enamel, the substance that protects teeth from damage and decay. A multi-disciplinary team of scientists led this effort. This is a critical first step to the long-term goal to develop stem cell-based treatments to repair damaged teeth and regenerate those that are lost. Enamel is made during tooth formation by specialized cells called amelobasts. These cells die off after tooth formation is complete. Consequently, the body has no way to repair or regenerate damaged enamel. Mon, 14 Aug 2023 12:22:58 EDT //www.koonmotors.com/releases/2023/08/230814122258.htm Research sheds new light on gene therapy for blood disorders //www.koonmotors.com/releases/2023/08/230809164732.htm A study shows new steps toward more patients getting gene therapy. Wed, 09 Aug 2023 16:47:32 EDT //www.koonmotors.com/releases/2023/08/230809164732.htm Stem cell therapy rescues symptoms of Alzheimer's disease //www.koonmotors.com/releases/2023/08/230809164724.htm Promising preclinical results show hematopoietic stem cell therapy was effective in rescuing memory loss, neuroinflammation and beta amyloid build-up in a mouse model of Alzheimer's disease. Wed, 09 Aug 2023 16:47:24 EDT //www.koonmotors.com/releases/2023/08/230809164724.htm Childhood cancer: 'New' immune system responds better to therapy //www.koonmotors.com/releases/2023/08/230809130650.htm Scientists have shown that immunotherapy after stem cell transplantation effectively combats certain nerve tumors in children. Crucially, stem cells from a parent provide children with a new immune system that responds much better to immunotherapies. Wed, 09 Aug 2023 13:06:50 EDT //www.koonmotors.com/releases/2023/08/230809130650.htm Researchers find an epigenetic key that unlocks common deadly cancers //www.koonmotors.com/releases/2023/07/230731144132.htm In skin, some aberrant adult epidermal stem cells turn on SOX9, kickstarting a process that ultimately activates cancer genes. Mon, 31 Jul 2023 14:41:32 EDT //www.koonmotors.com/releases/2023/07/230731144132.htm Neonatal stem cells from the heart could treat Crohn's disease //www.koonmotors.com/releases/2023/07/230728121132.htm Research found that direct injection of neonatal mesenchymal stem cells, derived from heart tissue discarded during surgery, reduces intestinal inflammation and promotes wound healing in a mouse model of Crohn's disease-like ileitis, an illness marked by chronic intestinal inflammation and progressive tissue damage. The study offers a promising new and alternative treatment approach that avoids the pitfalls of current Crohn's disease medications, including diminishing effectiveness, severe side effects and increased risk of gastrointestinal dysfunction. Fri, 28 Jul 2023 12:11:32 EDT //www.koonmotors.com/releases/2023/07/230728121132.htm Researchers reverse chemotherapy-related fertility loss using cell-based therapy //www.koonmotors.com/releases/2023/07/230721113238.htm 临床前研究表明,注射卵巢tissue-derived differentiated induced pluripotent stem cells can restore hormone production and fertility in mice with premature ovarian failure related to genetic diseases and cancer treatment. Fri, 21 Jul 2023 11:32:38 EDT //www.koonmotors.com/releases/2023/07/230721113238.htm Powerhouse proteins protect heart cells from chemotherapy damage //www.koonmotors.com/releases/2023/07/230721113135.htm Researchers have identified a process by which enzymes can help prevent heart damage in chemotherapy patients. Fri, 21 Jul 2023 11:31:35 EDT //www.koonmotors.com/releases/2023/07/230721113135.htm Researchers generate human embryo-like structures that include extraembryonic tissue //www.koonmotors.com/releases/2023/07/230720124849.htm Gastrulation, the process where an embryo reorganizes itself from a hollow sphere into a multilayered structure, is considered a 'black box' of human development. This is because human embryos are typically not cultured for longer than 14 days because of bioethical concerns, and gastrulation occurs between 17- and 21-days post-fertilization. In addition, current stem cell models that mimic gastrulation have not been able to include the necessary extraembryonic tissues that give rise to the yolk sac and the placenta. Researchers now report a new method to develop 'peri-gastruloids,' an embryo-like structure that includes one of the supporting tissues, the yolk sac, missing from previous models. Thu, 20 Jul 2023 12:48:49 EDT //www.koonmotors.com/releases/2023/07/230720124849.htm Study optimizes patient-specific stem cell-based therapy for Parkinson's disease //www.koonmotors.com/releases/2023/07/230719150009.htm A new discovery paves the way for clinical trials that use patients' own cells to treat Parkinson's disease. Wed, 19 Jul 2023 15:00:09 EDT //www.koonmotors.com/releases/2023/07/230719150009.htm Wnt signalling interpreted differently depending on the receiving cell and signal duration //www.koonmotors.com/releases/2023/07/230719112618.htm The same message can be interpreted differently by different individuals -- also among cells. This is shown in a study by researchers who studied cell communication through Wnt signalling, which plays a decisive role in embryo development and cancer. Their findings are surprising in light of the prevailing conception of how Wnt signalling works. Wed, 19 Jul 2023 11:26:18 EDT //www.koonmotors.com/releases/2023/07/230719112618.htm Innovative stem cell research takes aim at origins of human cancers //www.koonmotors.com/releases/2023/06/230628130408.htm In an exciting new study adding to the global pool of knowledge about the roots of human cancers, researchers are establishing a clear link between different types of cancers and their embryonic origins. They also identify new concepts that can be considered in future drug discovery projects and used in standard chemotherapeutics in the clinic. Wed, 28 Jun 2023 13:04:08 EDT //www.koonmotors.com/releases/2023/06/230628130408.htm New drug delivery method can reverse senescence of stem cells //www.koonmotors.com/releases/2023/06/230627191524.htm As we age, our bodies change and degenerate over time in a process called senescence. Stem cells, which have the unique ability to change into other cell types, also experience senescence, which presents an issue when trying to maintain cell cultures for therapeutic use. The biomolecules produced by these cell cultures are important for various medicines and treatments, but once the cells enter a senescent state they stop producing them, and worse, they instead produce biomolecules antagonistic to these therapeutics. In a recently published study, researchers describe a new method for reversing senescence in stem cells through delivering antioxidants in the form of a crystal. Tue, 27 Jun 2023 19:15:24 EDT //www.koonmotors.com/releases/2023/06/230627191524.htm New model provides unprecedented window into human embryonic development //www.koonmotors.com/releases/2023/06/230627141940.htm 两到三周fter conception, an embryo faces a critical point in its development. In the stage known as gastrulation, the transformation of embryonic cells into specialized cells begins. This initiates an explosion of cellular diversity in which the embryonic cells later become the precursors of future blood, tissue, muscle, and more types of cells, and the primitive body axes start to form. Studying this process in the human-specific context has posed significant challenges to biologists, but new research offers an unprecedented window into this point in time in human development. Tue, 27 Jun 2023 14:19:40 EDT //www.koonmotors.com/releases/2023/06/230627141940.htm Human embryo-like models created from stem cells to understand earliest stages of human development //www.koonmotors.com/releases/2023/06/230627123010.htm Scientists have created a stem cell-derived model of the human embryo in the lab by reprogramming human stem cells. The breakthrough could help research into genetic disorders and in understanding why and how pregnancies fail. Tue, 27 Jun 2023 12:30:10 EDT //www.koonmotors.com/releases/2023/06/230627123010.htm The speed of life: A zoo of cells to study developmental time //www.koonmotors.com/releases/2023/06/230620113815.htm Researchers have used an unprecedented stem cell zoo to compare six different mammalian species and their developmental time. Tue, 20 Jun 2023 11:38:15 EDT //www.koonmotors.com/releases/2023/06/230620113815.htm Coaxing hair growth in aging hair follicle stem cells //www.koonmotors.com/releases/2023/06/230605181227.htm Scientists discovered how to soften hair follicle stem cells to enable them to grow hair again. These cells stiffen with age and produce less hair. In a study in mice, the investigators report that they can soften the stem cells by boosting the production of a tiny RNA, miR-205, that relaxes the hardness of the cells. When scientists genetically manipulated the stem cells to produce more miR-205, it promoted hair growth in young and old mice. Mon, 05 Jun 2023 18:12:27 EDT //www.koonmotors.com/releases/2023/06/230605181227.htm Lab-grown mini lungs could accelerate the study of respiratory diseases //www.koonmotors.com/releases/2023/06/230601155927.htm Researchers have collaborated to refine a cell culture technology platform that grows genetically identical lung buds from human embryonic stem cells. Thu, 01 Jun 2023 15:59:27 EDT //www.koonmotors.com/releases/2023/06/230601155927.htm Gene engineered cell therapy developed to target brain metastatic melanomas //www.koonmotors.com/releases/2023/05/230531150214.htm Overall survival for patients with melanoma that has spread to the brain is only four to six months. Immunotherapies, which harness the power of the immune system to attack cancer cells, have garnered excitement in recent years for their potential to revolutionize the treatment of metastatic melanomas, but results from early clinical studies indicate that the prognosis for most patients remains poor. Now, scientists have integrated multiple therapeutic approaches to more effectively target melanoma in the brain. In preclinical studies, the scientists successfully activated immune responses in sophisticated mouse models that mimic human settings. Wed, 31 May 2023 15:02:14 EDT //www.koonmotors.com/releases/2023/05/230531150214.htm Scientists unveil RNA-guided mechanisms driving cell fate //www.koonmotors.com/releases/2023/05/230530125442.htm The early stages of embryonic development contain many of life's mysteries. Unlocking these mysteries can help us better understand early development and birth defects, and help develop new regenerative medicine treatments. Researchers have now characterized a critical time in mammalian embryonic development using powerful and innovative imaging techniques. Tue, 30 May 2023 12:54:42 EDT //www.koonmotors.com/releases/2023/05/230530125442.htm Researchers design an innovative strategy to fight obesity through gene therapy //www.koonmotors.com/releases/2023/05/230530125435.htm A scientific team has designed a strategy to fight obesity and diabetes in mice through ex vivo gene therapy which consists of implanting cells that have been manipulated and transformed in order to treat a disease. This is the first study to apply the ex vivo gene therapy technique to generate and implant cells that express the CPT1AM protein, an enzyme that plays a decisive role in many metabolic diseases such as obesity. Tue, 30 May 2023 12:54:35 EDT //www.koonmotors.com/releases/2023/05/230530125435.htm Scientists target human stomach cells for diabetes therapy //www.koonmotors.com/releases/2023/05/230525141422.htm Stem cells from the human stomach can be converted into cells that secrete insulin in response to rising blood sugar levels, offering a promising approach to treating diabetes, according to a preclinical study. Thu, 25 May 2023 14:14:22 EDT //www.koonmotors.com/releases/2023/05/230525141422.htm Researchers successfully induce primate oocytes in the lab //www.koonmotors.com/releases/2023/05/230525141343.htm The many types of cells in the human body are produced through the process of differentiation, in which stem cells are converted to more specialized types. Currently, it is challenging for researchers to control the differentiation of stem cells in the lab (in vitro). Of particular interest are oocytes, which are female germ cells that develop into eggs. Understanding their development could have far-ranging impacts, from infertility treatment to conservation of endangered species. A new study has successfully induced meiotic (dividing) oocytes from the embryonic stem cells of cynomolgus monkeys, which share many physiological traits with humans. By establishing a culture method for inducing the differentiation of meiotic oocytes, the researchers aimed to shed light on germ cell development in both humans and other primates. Thu, 25 May 2023 14:13:43 EDT //www.koonmotors.com/releases/2023/05/230525141343.htm A look inside stem cells helps create personalized regenerative medicine //www.koonmotors.com/releases/2023/05/230512110223.htm Researchers have examined a specific type of stem cell with an intracellular toolkit to determine which cells are most likely to create effective cell therapies. Fri, 12 May 2023 11:02:23 EDT //www.koonmotors.com/releases/2023/05/230512110223.htm Gamma delta T cells can fight aggressive breast cancer //www.koonmotors.com/releases/2023/05/230504094944.htm Researchers discover a mechanism by which cancer cells escape the immune system. Thu, 04 May 2023 09:49:44 EDT //www.koonmotors.com/releases/2023/05/230504094944.htm A novel stem cell adhesive using mussels //www.koonmotors.com/releases/2023/05/230503085331.htm A team of researchers develops stem cell adhesive for arthritis treatment using mussel adhesion protein and hyaluronic acid. Wed, 03 May 2023 08:53:31 EDT //www.koonmotors.com/releases/2023/05/230503085331.htm Engineering the next generation of cell and gene therapies //www.koonmotors.com/releases/2023/04/230420135317.htm Investigators are developing a novel way to treat amyotrophic lateral sclerosis (ALS) and retinitis pigmentosa using engineered stem cells that may eventually lead to personalized treatments. Thu, 20 Apr 2023 13:53:17 EDT //www.koonmotors.com/releases/2023/04/230420135317.htm Study links 'stuck' stem cells to hair turning gray //www.koonmotors.com/releases/2023/04/230419125056.htm Certain stem cells have a unique ability to move between growth compartments in hair follicles, but get stuck as people age and so lose their ability to mature and maintain hair color, a new study shows. Wed, 19 Apr 2023 12:50:56 EDT //www.koonmotors.com/releases/2023/04/230419125056.htm Healing the unhealable: New approach helps bones mend themselves //www.koonmotors.com/releases/2023/04/230414113455.htm Young babies and newborn mice can naturally heal damage to the bones that form the top of the skull, but this ability is lost in adults. Researchers developed a novel approach that promoted bone regeneration in mice without implantation of bone tissue or biomaterials. Fri, 14 Apr 2023 11:34:55 EDT //www.koonmotors.com/releases/2023/04/230414113455.htm 科学家对余额达到不错的效果ring vision in blindness caused by cellular degeneration in the eye //www.koonmotors.com/releases/2023/04/230413231630.htm Research reveals a promising stem cell approach to correct photoreceptor cell degeneration, which underlies several forms of visual decline and blindness. Thu, 13 Apr 2023 23:16:30 EDT //www.koonmotors.com/releases/2023/04/230413231630.htm Researchers create embryo-like structures from monkey embryonic stem cells //www.koonmotors.com/releases/2023/04/230406113953.htm Human embryo development and early organ formation remain largely unexplored due to ethical issues surrounding the use of embryos for research as well as limited availability of materials to study. Investigators now report on the creation of embryo-like structures from monkey embryonic stem cells. The investigators also transferred these embryo-like structures into the uteruses of female monkeys and determined that the structures were able to implant and elicit a hormonal response similar to pregnancy. Thu, 06 Apr 2023 11:39:53 EDT //www.koonmotors.com/releases/2023/04/230406113953.htm A miniature heart in a petri dish: Organoid emulates development of the human heart //www.koonmotors.com/releases/2023/04/230404114235.htm A team has induced stem cells to emulate the development of the human heart. The result is a sort of 'mini-heart' known as an organoid. It will permit the study of the earliest development phase of our heart and facilitate research on diseases. Tue, 04 Apr 2023 11:42:35 EDT //www.koonmotors.com/releases/2023/04/230404114235.htm Simultaneous diagnosis and treatment of cancer now possible //www.koonmotors.com/releases/2023/04/230404114137.htm Researchers demonstrate therapeutic effects of tumor-initiating cell probe TiY after demonstrating its staining effects. Tue, 04 Apr 2023 11:41:37 EDT //www.koonmotors.com/releases/2023/04/230404114137.htm Patient-specific cells generated from thymus organoids //www.koonmotors.com/releases/2023/03/230323135530.htm Researchers have used pluripotent stem cells to make thymus organoids that support the development of patient-specific T-cells. The proof-of-concept work provides the basis for studying human thymus function, T-cell development, and transplant immunity. Thu, 23 Mar 2023 13:55:30 EDT //www.koonmotors.com/releases/2023/03/230323135530.htm Why does a leukemic mutation not always lead to leukemia? //www.koonmotors.com/releases/2023/03/230323135506.htm 科学家发现了一种机制,联系在一起a leukemic mutation to varying potentials for disease development -- a discovery which could eventually lead to a way to identify patients with the mutation who are most at risk. The mutation is in a gene called TET2, which is prevalent in patients with myeloid leukemia. The scientists labeled and tracked individual blood stem cells in mice with the mutation and found that a subset of blood stem cells and their progeny -- known as clones -- made an outsized contribution to the overall population of blood and immune cells. The over-contributing clones tended to produce a lot of 'myeloid' cells including immune cells called granulocytes, which may potentially lead to myeloid leukemia. Thu, 23 Mar 2023 13:55:06 EDT //www.koonmotors.com/releases/2023/03/230323135506.htm To ward off aging, stem cells must take out the trash //www.koonmotors.com/releases/2023/03/230321135143.htm Researchers find stem cells use a surprising system for discarding misfolded proteins. This unique pathway could be the key to maintaining long-term health and preventing age-related blood and immune disorders. Tue, 21 Mar 2023 13:51:43 EDT //www.koonmotors.com/releases/2023/03/230321135143.htm What makes blood stem cells transform? Regulation of RNA splicing may be an answer //www.koonmotors.com/releases/2023/03/230321112619.htm Researchers have determined a novel mechanism linking the metabolism of ribonucleic acids, RNA, to the development of leukemia in myelodysplastic syndrome patients, MDS. They explain what makes hematopoietic stem cells acquire malignant traits in cancer. Tue, 21 Mar 2023 11:26:19 EDT //www.koonmotors.com/releases/2023/03/230321112619.htm Study uses base editing to correct mutation that causes rare immune deficiency //www.koonmotors.com/releases/2023/03/230320172600.htm 一个条件称为CD3δSCID引起的mutation in the CD3D gene, which prevents the production of the CD3 delta protein that is needed for the normal development of T cells from blood stem cells. Researchers showed that a new genome editing technique called base editing can correct the mutation that causes CD3 delta SCID in blood stem cells and restore their ability to produce T cells. Base editing is an ultraprecise form of genome editing that enables scientists to correct single-letter mutations in DNA. Mon, 20 Mar 2023 17:26:00 EDT //www.koonmotors.com/releases/2023/03/230320172600.htm Genes that form specific bones in the womb heal them later in life //www.koonmotors.com/releases/2023/03/230320143746.htm Genes long known to control the formation of bones before birth also control bone healing later in life, a new study found. Mon, 20 Mar 2023 14:37:46 EDT //www.koonmotors.com/releases/2023/03/230320143746.htm Discovery of an unexpected function of blood immune cells: Their ability to proliferate //www.koonmotors.com/releases/2023/03/230317144955.htm The ability of a cell to divide, to proliferate, is essential for life and gives rise to the formation of complex organisms from a single cell. It also allows the replacement of used cells from a limited number of 'stem' cells, which then proliferate and specialize. In cancer, however, cell proliferation is no longer controlled and becomes chaotic. Researchers have discovered that, in a healthy individual, certain blood immune cells, the monocytes, also have this ability to proliferate, with the aim to replace tissue macrophages, which are essential for the proper functioning of our body. Fri, 17 Mar 2023 14:49:55 EDT //www.koonmotors.com/releases/2023/03/230317144955.htm Filling a niche: Neural stem cells help maintain their microenvironment //www.koonmotors.com/releases/2023/03/230315132442.htm Researchers shed light on the neural stem and progenitor cell (NSPC) microenvironment during development. Neurosphere formation from embryonic mouse forebrain NSPCs was significantly increased under low oxygen conditions, and VEGF-A was identified as a factor released by NSPCs to contribute to this effect. This study demonstrates that NSPCs appear to maintain their own niche and population under low oxygen conditions during development. Wed, 15 Mar 2023 13:24:42 EDT //www.koonmotors.com/releases/2023/03/230315132442.htm How to assemble a complete jaw //www.koonmotors.com/releases/2023/03/230310123924.htm The skeleton, tendons, and glands of a functional jaw all derive from the same population of stem cells, which arise from a cell population known as neural crest. To discover how these neural crest-derived cells know to make the right type of cell in the right location, researchers focused on a particular gene, Nr5a2, that was active in a region of the face that makes tendons and glands, but not skeleton. To understand the role of Nr5a2, the scientists created zebrafish lacking this gene. These mutant zebrafish generated excess cartilage and were missing tendons in their jaws. Fri, 10 Mar 2023 12:39:24 EST //www.koonmotors.com/releases/2023/03/230310123924.htm Researchers discover therapeutic target to aid in glaucoma treatment //www.koonmotors.com/releases/2023/03/230310103513.htm Researchers have identified a new therapeutic target that could lead to more effective treatment of glaucoma. Fri, 10 Mar 2023 10:35:13 EST //www.koonmotors.com/releases/2023/03/230310103513.htm New stem cell model developed for research into a life-threatening malformation of the newborn lung //www.koonmotors.com/releases/2023/03/230309101341.htm Congenital diaphragmatic hernia is one of the deadliest birth defects. To better understand and treat this condition in the future, researchers designed a new cell model in the laboratory and tested a drug therapy on it. Thu, 09 Mar 2023 10:13:41 EST //www.koonmotors.com/releases/2023/03/230309101341.htm Research finds hope in stem cell therapy for perianal fistulas in patients with Crohn's disease //www.koonmotors.com/releases/2023/03/230303105317.htm A dissolvable plug delivered stem cell therapy with few side effects in patients with single tract perianal fistulas, researchers discovered. Fri, 03 Mar 2023 10:53:17 EST //www.koonmotors.com/releases/2023/03/230303105317.htm How to generate new neurons in the brain //www.koonmotors.com/releases/2023/03/230301141432.htm Some areas of the adult brain contain quiescent, or dormant, neural stem cells that can potentially be reactivated to form new neurons. However, the transition from quiescence to proliferation is still poorly understood. A team has discovered the importance of cell metabolism in this process and identified how to wake up these neural stem cells and reactivate them. Biologists succeeded in increasing the number of new neurons in the brain of adult and even elderly mice. Wed, 01 Mar 2023 14:14:32 EST //www.koonmotors.com/releases/2023/03/230301141432.htm Successful cure of HIV infection after stem cell transplantation, study suggests //www.koonmotors.com/releases/2023/02/230224165409.htm Haematopoietic stem cell transplantation for the treatment of severe blood cancers is the only medical intervention that has cured two people living with HIV in the past. An international group of physicians and researchers has now identified another case in which HIV infection has been shown to be cured in the same way. The successful healing process of this third patient was for the first time characterized in great detail virologically and immunologically over a time span of ten years. 星期五,2023年2月24日16:54:09 EST //www.koonmotors.com/releases/2023/02/230224165409.htm Head injuries could be a risk factor for developing brain cancer //www.koonmotors.com/releases/2023/02/230224135003.htm Previous studies have suggested a possible link between head injury and increased rates of brain tumors but evidence has been limited and often inconclusive. A team has now identified a possible mechanism to explain this link, implicating genetic mutations acting in concert with brain tissue inflammation to change the behavior of cells, making them more likely to become cancerous. Although this study was largely carried out in mice, it suggests that it would be important to explore the relevance of these findings to human gliomas. Fri, 24 Feb 2023 13:50:03 EST //www.koonmotors.com/releases/2023/02/230224135003.htm First stem cells from a bat species known to harbor SARS-CoV-2 could shed light on virus survival and molecular adaptability //www.koonmotors.com/releases/2023/02/230221112958.htm Researchers have generated the first induced pluripotent stem cells (iPSCs) from bats, gaining valuable insights into the close relationship between bats and viruses. Tue, 21 Feb 2023 11:29:58 EST //www.koonmotors.com/releases/2023/02/230221112958.htm Packaged DNA: New method to promote bone growth //www.koonmotors.com/releases/2023/02/230209094140.htm DNA can help to stimulate bone healing in a localized and targeted manner, for example after a complicated fracture or after severe tissue loss following surgery. Scientists have developed a new process in which they coat implant materials with a gene-activated biomaterial that induces stem cells to produce bone tissue. Thu, 09 Feb 2023 09:41:40 EST //www.koonmotors.com/releases/2023/02/230209094140.htm Will revitalizing old blood slow aging? //www.koonmotors.com/releases/2023/02/230206170612.htm Young blood may be an elixir for older bodies, rejuvenating aging hearts, muscles, and brains. But how can old blood become young again? Stem cell scientists may have found a way. Mon, 06 Feb 2023 17:06:12 EST //www.koonmotors.com/releases/2023/02/230206170612.htm