//www.koonmotors.com/news/health_medicine/pharmaceuticals/ Research news on the pharmaceutical industry including new drugs and interventions. en-us Wed, 06 Sep 2023 14:45:07 EDT Wed, 06 Sep 2023 14:45:07 EDT 60 //www.koonmotors.com/images/scidaily-logo-rss.png//www.koonmotors.com/news/health_medicine/pharmaceuticals/ For more science news, visit ScienceDaily. //www.koonmotors.com/releases/2023/09/230906135638.htm New findings suggest that treating insomnia can stop opioid-seeking behavior, even after ending treatment. Wed, 06 Sep 2023 13:56:38 EDT //www.koonmotors.com/releases/2023/09/230906135638.htm //www.koonmotors.com/releases/2023/09/230904104625.htm Scientists have discovered two new genes that cause head and neck cancer patients to be resistant to chemotherapy, and that silencing either gene can make cancer cells previously unresponsive to chemotherapy subsequently respond to it. Mon, 04 Sep 2023 10:46:25 EDT //www.koonmotors.com/releases/2023/09/230904104625.htm //www.koonmotors.com/releases/2023/08/230830133608.htm Antibiotic-resistant bacteria get extra nutrients and thrive when the drugs kill 'good' bacteria in the gut, according to new research that could lead to better patient risk assessment and 'microbiome therapeutics' treatments to help combat antibiotic-resistant bacteria. Wed, 30 Aug 2023 13:36:08 EDT //www.koonmotors.com/releases/2023/08/230830133608.htm //www.koonmotors.com/releases/2023/08/230830131950.htm Australian researchers have found an existing blood cancer drug can kill 'silent' HIV cells and delay reinfections -- a significant pre-clinical discovery that could lead to a future cure for the disease. Wed, 30 Aug 2023 13:19:50 EDT //www.koonmotors.com/releases/2023/08/230830131950.htm //www.koonmotors.com/releases/2023/08/230830130846.htm 研究人员应用一种新的技术来生成the full inventory of mutations in the bacterial species Escherichia coli where the antibiotic rifampicin attaches to and disables an essential bacterial enzyme known as RNA polymerase (RNAP). Wed, 30 Aug 2023 13:08:46 EDT //www.koonmotors.com/releases/2023/08/230830130846.htm //www.koonmotors.com/releases/2023/08/230829130007.htm Modern blood-thinning drugs (known as NOACs) reduce the risk of serious bleeding by up to 45 percent compared to the traditional drug warfarin in the treatment of blood clots in the legs and lungs, according to a recent study. Tue, 29 Aug 2023 13:00:07 EDT //www.koonmotors.com/releases/2023/08/230829130007.htm //www.koonmotors.com/releases/2023/08/230829125932.htm Early laboratory results in mice show the drug PXS-5505 increases survival when combined with chemotherapy in the treatment of pancreatic ductal adenocarcinomas. Tue, 29 Aug 2023 12:59:32 EDT //www.koonmotors.com/releases/2023/08/230829125932.htm //www.koonmotors.com/releases/2023/08/230829125828.htm A new study suggests rough surfaces inspired by the bacteria-killing spikes on insect wings may be more effective at combating drug-resistant superbugs, including fungus, than previously understood. Tue, 29 Aug 2023 12:58:28 EDT //www.koonmotors.com/releases/2023/08/230829125828.htm //www.koonmotors.com/releases/2023/08/230828223807.htm After a nearly threefold drop in prescriptions for the antibiotic ciprofloxacin between 2015 and 2021, the rates of ciprofloxacin-resistant E. coli bacteria circulating in the community did not decline. In fact, a study of Seattle-area women over age 50 who had not taken any antibiotics for at least a year discovered that the incidence of gut-colonizing ciprofloxacin-resistant E. coli actually increased. About 1 in 5 women in the study were affected. The results are consistent with theoretical models indicating that, once a drug-resistant form of E.coli emerges, it will continue to spread by taking up long-term residence in individuals' gut microbiomes. Antibiotic resistant E. coli in the gut is of concern because the bacteria can enter the urinary tract and cause difficult-to-treat infections, particularly in women. Evidence from studies such as this one may be changing paradigms on how to fight the rise in antibiotic resistance. Mon, 28 Aug 2023 22:38:07 EDT //www.koonmotors.com/releases/2023/08/230828223807.htm //www.koonmotors.com/releases/2023/08/230828105543.htm New research details the first oral drug for the treatment of a type of high cholesterol -- called Lp(a) -- that is a potentially more dangerous version of the so called 'bad' cholesterol, LDL, because it is stickier and may be more likely to cause blockages and blood clots in your arteries. It is estimated that up to 20% of people worldwide have high levels of Lp(a), which is associated with a person's risk of experiencing a heart attack, strokes or other serious cardiac event. Importantly Lp(a) can be present even in younger adults and otherwise healthy people with no other known cardiovascular risks -- and often remains undetected until a cardiac event has occurred. Mon, 28 Aug 2023 10:55:43 EDT //www.koonmotors.com/releases/2023/08/230828105543.htm //www.koonmotors.com/releases/2023/08/230822111734.htm A new powerful antibiotic, isolated from bacteria that could not be studied before, seems capable of combating harmful bacteria and even multi-resistant 'superbugs'. Named Clovibactin, the antibiotic appears to kill bacteria in an unusual way, making it more difficult for bacteria to develop any resistance against it. Tue, 22 Aug 2023 11:17:34 EDT //www.koonmotors.com/releases/2023/08/230822111734.htm //www.koonmotors.com/releases/2023/08/230821174253.htm The world needs greener ways to make chemicals. In a new study, researchers demonstrate one potential path toward this goal by adapting hydrogen fuel cell technologies. Mon, 21 Aug 2023 17:42:53 EDT //www.koonmotors.com/releases/2023/08/230821174253.htm //www.koonmotors.com/releases/2023/08/230821114401.htm Various medical circumstances, including heart attacks and extreme cases of COVID-19, necessitate the use of anticoagulants, medicines that prevent blood clots. But the most commonly used, heparin, can induce potentially fatal side effects by making the blood clots worse rather than better. This only happens in a minority of patients so effective treatments are not commonly explored. Researchers have now proposed a side effect-free anticoagulating treatment that has so far proved effective in test mice and could be ready for human trials in just a few years. Mon, 21 Aug 2023 11:44:01 EDT //www.koonmotors.com/releases/2023/08/230821114401.htm //www.koonmotors.com/releases/2023/08/230817163920.htm Obesity leads to altered energy metabolism and reduced insulin sensitivity of cells. The so-called 'anti-obesity drugs' are increasingly used to treat obesity and have caused tremendous interest, especially in the USA. Researchers have now shown in people with obesity that reduced insulin sensitivity affects learning of sensory associations. A single dose of the anti-obesity drug liraglutide was able to normalize these changes and restore the underlying brain circuit function. Thu, 17 Aug 2023 16:39:20 EDT //www.koonmotors.com/releases/2023/08/230817163920.htm //www.koonmotors.com/releases/2023/08/230817163838.htm Cooking food thoroughly and avoiding some types of vegetables and salad during a course of antibiotic treatment could potentially reduce antibiotic resistance, by preventing bacteria carrying resistance genes getting into the gut, according to a new study. Thu, 17 Aug 2023 16:38:38 EDT //www.koonmotors.com/releases/2023/08/230817163838.htm //www.koonmotors.com/releases/2023/08/230815131824.htm New cancer drugs are being launched at a rapid pace, before their long-term effectiveness for patients can be evaluated. Several years later, most of them still lack scientific evidence for actually increasing life expectancy or improving quality of life. Tue, 15 Aug 2023 13:18:24 EDT //www.koonmotors.com/releases/2023/08/230815131824.htm //www.koonmotors.com/releases/2023/08/230814122249.htm Scientists have uncovered new molecular targets on a cell receptor that play a major role in cardiovascular regulation. The findings could lead to improved drugs for heart disease, an unfortunate side effect of some cancer therapies. Mon, 14 Aug 2023 12:22:49 EDT //www.koonmotors.com/releases/2023/08/230814122249.htm //www.koonmotors.com/releases/2023/08/230810110422.htm New research has demonstrated the safety and tolerability of a new drug treatment designed as a therapeutic intervention for spinal cord injury (SCI). Thu, 10 Aug 2023 11:04:22 EDT //www.koonmotors.com/releases/2023/08/230810110422.htm //www.koonmotors.com/releases/2023/08/230809164729.htm 科学的旅程几十年做傻人nd a new antibiotic strategy to defeat gram-negative bacteria like Salmonella, Pseudomonas and E. coli, the culprits in many urinary tract infections. The synthetic molecule works fast and is durable. It interferes with synthesis of the bacterial outer membrane by jamming an enzyme. When tested against a clinical collection of 285 bacterial strains, including some that were highly resistant to commercial antibiotics, it killed them all. Wed, 09 Aug 2023 16:47:29 EDT //www.koonmotors.com/releases/2023/08/230809164729.htm //www.koonmotors.com/releases/2023/08/230808110833.htm Overly active immune cells are often behind lung damage in diseases such as Covid-19. Researchers have developed an RNA agent for a lung spray that slows the activity of these cells, known as macrophages. A new, sugar-based transport mechanism is especially effective in bringing the therapeutic to its target. Tue, 08 Aug 2023 11:08:33 EDT //www.koonmotors.com/releases/2023/08/230808110833.htm //www.koonmotors.com/releases/2023/08/230807133810.htm An antibody therapy appears to have advantages over existing opioid-overdose treatments. Mon, 07 Aug 2023 13:38:10 EDT //www.koonmotors.com/releases/2023/08/230807133810.htm //www.koonmotors.com/releases/2023/08/230806211625.htm The antibiotic cefazolin is an essential drug according to the World Health Organization (WHO). It is usually produced via batch manufacturing, but this multistep process is time-consuming, wasteful and requires very specialized facilities. Now, researchers have manufactured cefazolin using the continuous-flow method. This method is cheaper, quicker, less wasteful and more flexible in terms of how much drug can be produced when it's needed. Improving access to cefazolin is vital for global health and particularly relevant for countries such as Japan, which experienced a shortage in 2019. Sun, 06 Aug 2023 21:16:25 EDT //www.koonmotors.com/releases/2023/08/230806211625.htm //www.koonmotors.com/releases/2023/08/230801105034.htm Researchers have discovered a new way to attack fungal infections. The key is to block fungi from being able to make fatty acids, the major component of fats. Resistance to anti-fungal drugs is increasing and this new approach will be particularly useful because it works in a new way and affects a broad range of fungal species. Tue, 01 Aug 2023 10:50:34 EDT //www.koonmotors.com/releases/2023/08/230801105034.htm //www.koonmotors.com/releases/2023/08/230801105021.htm Ion channels play a crucial role in many cellular processes, including neuronal communication, muscle contraction or cell proliferation. Most multi subunit ion channels exist in two functional states, either closed or open. During gating, one should expect that all subunits undergo conformational changes. The absence of intermediate conduction levels is surprising and asks for an explanation. A team of researchers has created a smart model system to answer this important question. 星期二,2023年8月01 10:50:21美国东部时间 //www.koonmotors.com/releases/2023/08/230801105021.htm //www.koonmotors.com/releases/2023/07/230724122651.htm Neuropathic pain is a debilitating condition estimated to affect as much as 10% of the global population. It results from a damaged or malfunctioning nervous system, stemming from diseases like diabetes, alcoholism, strokes, Parkinson's and other causes like spinal nerve compression, radiation and chemotherapy treatments. Management of neuropathic pain has been particularly challenging as currently prescribed drugs, such as anticonvulsants and antidepressants can have severe adverse effects, are not well-tolerated, take a longer time to work only help a subset of patients. Mon, 24 Jul 2023 12:26:51 EDT //www.koonmotors.com/releases/2023/07/230724122651.htm //www.koonmotors.com/releases/2023/07/230722004700.htm Researchers have discovered the molecular mechanisms by which the human immunodeficiency virus (HIV) becomes resistant to Dolutegravir, one of the most effective, clinically used antiviral drugs for treating HIV. Their findings reveal how changes to the 3D structures of integrase, an HIV protein, can lead to Dolutegravir resistance and how other compounds may be able to overcome this resistance. Sat, 22 Jul 2023 00:47:00 EDT //www.koonmotors.com/releases/2023/07/230722004700.htm //www.koonmotors.com/releases/2023/07/230720124954.htm One of the world's largest studies on the impact of cholesterol-lowering medication has good and bad news for the 200 million people who take statins or other medication for high cholesterol. Thu, 20 Jul 2023 12:49:54 EDT //www.koonmotors.com/releases/2023/07/230720124954.htm //www.koonmotors.com/releases/2023/07/230719112638.htm Drug-resistant bacteria represent a major threat to public health worldwide, and scientists are constantly searching for novel antibiotic compounds. In a recent study, a research team achieved the first artificial synthesis of tanzawaic acid B, a promising antibiotic drug candidate, on gram scale. Their findings can make synthetic tanzawaic acids widely available, paving the way for the discovery of new drugs. Wed, 19 Jul 2023 11:26:38 EDT //www.koonmotors.com/releases/2023/07/230719112638.htm //www.koonmotors.com/releases/2023/07/230717115837.htm A recent study centers around the idea that various anti-inflammatory drugs could be effective treatments for Alzheimer's disease. This study focused on a protein known as p38. Many labs have been working with this protein as a potential target for drug development to treat Alzheimer's disease and other conditions with neuroinflammatory dysfunction. Mon, 17 Jul 2023 11:58:37 EDT //www.koonmotors.com/releases/2023/07/230717115837.htm //www.koonmotors.com/releases/2023/07/230717115822.htm Pharmaceutical scientists and biologists are teaming up to make the next generation of lipid nanoparticles (LNPs) for drug delivery. Combining structural biology with cutting edge pharmaceutical science, the team is designing LNPs that can precisely deliver vaccines and therapeutics to target tissues while improving the product's shelf life and duration of action. Mon, 17 Jul 2023 11:58:22 EDT //www.koonmotors.com/releases/2023/07/230717115822.htm //www.koonmotors.com/releases/2023/07/230714114752.htm Promising results in a trial of ketamine for severe depression could lead to treatment becoming more affordable. Fri, 14 Jul 2023 11:47:52 EDT //www.koonmotors.com/releases/2023/07/230714114752.htm //www.koonmotors.com/releases/2023/07/230712124752.htm Cancer therapies that target specific genetic abnormalities in tumors have revolutionized treatment possibilities over the past two decades. While quality of life and survival are improved with targeted therapies, relapse is common due to the evolution of new tumor cells that are resistant to the targeted therapy. A new study reveals how lung tumors may develop drug resistance over time, pointing to a protein, called APOBEC3A, that could be a promising target. Results may help researchers develop new solutions for tumor resistance to targeted cancer therapies. Wed, 12 Jul 2023 12:47:52 EDT //www.koonmotors.com/releases/2023/07/230712124752.htm //www.koonmotors.com/releases/2023/07/230712124703.htm Leprosy has existed since at least Biblical times, yet scientists still don't know exactly how Mycobacterium leprae causes the disease's symptoms. Though antibiotics can treat the illness, researchers are concerned about the increase in drug-resistant strains. Now, a team has begun to understand the unique role certain immune receptors play in leprosy infections in mice, which could lead to new types of treatments for this disease and others in humans. Wed, 12 Jul 2023 12:47:03 EDT //www.koonmotors.com/releases/2023/07/230712124703.htm //www.koonmotors.com/releases/2023/07/230711133210.htm The World Health Organization lists bacteria that are resistant to antibiotics as one of the top 10 global health threats. Therefore, researchers are looking for new antibiotics to counter this resistance. Biophysicist have now discovered that the relatively new antibiotic AMC-109 affects the cell membrane of bacteria by disordering its organization. This differs from most other antibiotics and could open up new directions for future treatment and drug development. Tue, 11 Jul 2023 13:32:10 EDT //www.koonmotors.com/releases/2023/07/230711133210.htm //www.koonmotors.com/releases/2023/07/230710113634.htm A team of scientists has found that an existing cancer drug could be repurposed to target a subset of cancers that currently lack targeted treatment options and is often associated with poor outcomes. This subset of cancers makes up 15 per cent of all cancers and is especially prevalent in aggressive tumors such as osteosarcoma (bone tumor) and glioblastoma (brain tumor). Mon, 10 Jul 2023 11:36:34 EDT //www.koonmotors.com/releases/2023/07/230710113634.htm //www.koonmotors.com/releases/2023/07/230705171101.htm 照顾好你的牙齿可能与tter brain health, according to a new study. The study found that gum disease and tooth loss were linked to brain shrinkage in the hippocampus, which plays a role in memory and Alzheimer's disease. The study does not prove that gum disease or tooth loss causes Alzheimer's disease; it only shows an association. Wed, 05 Jul 2023 17:11:01 EDT //www.koonmotors.com/releases/2023/07/230705171101.htm //www.koonmotors.com/releases/2023/07/230701135745.htm A team of scientists from around the globe has gained high-res structural insights into a key bacterial enzyme, which may help chemists design new drugs to inhibit it and thus suppress disease-causing bacteria. Their work is important as fears continue to grow around rising rates of antibiotic resistance. Sat, 01 Jul 2023 13:57:45 EDT //www.koonmotors.com/releases/2023/07/230701135745.htm //www.koonmotors.com/releases/2023/06/230628125341.htm Researchers find a combination of drugs outperformed other treatments in human and mouse models of pancreatic cancer; now urge clinical trial. Wed, 28 Jun 2023 12:53:41 EDT //www.koonmotors.com/releases/2023/06/230628125341.htm //www.koonmotors.com/releases/2023/06/230628125327.htm Scientists have developed a new approach to produce life-saving oligonucleotide therapeutics on a large scale, in high purity, and with minimal environmental impacts. Wed, 28 Jun 2023 12:53:27 EDT //www.koonmotors.com/releases/2023/06/230628125327.htm //www.koonmotors.com/releases/2023/06/230627191524.htm As we age, our bodies change and degenerate over time in a process called senescence. Stem cells, which have the unique ability to change into other cell types, also experience senescence, which presents an issue when trying to maintain cell cultures for therapeutic use. The biomolecules produced by these cell cultures are important for various medicines and treatments, but once the cells enter a senescent state they stop producing them, and worse, they instead produce biomolecules antagonistic to these therapeutics. In a recently published study, researchers describe a new method for reversing senescence in stem cells through delivering antioxidants in the form of a crystal. Tue, 27 Jun 2023 19:15:24 EDT //www.koonmotors.com/releases/2023/06/230627191524.htm //www.koonmotors.com/releases/2023/06/230623161134.htm Researchers report that, in laboratory cultures and animal models, a drug significantly reduces the ability of bacteria to develop antibiotic resistance, which might prolong antibiotic effectiveness. Fri, 23 Jun 2023 16:11:34 EDT //www.koonmotors.com/releases/2023/06/230623161134.htm //www.koonmotors.com/releases/2023/06/230622182828.htm Researchers invented a new reporting technique to monitor activity of CaMKII while screening the effects of nearly 5,000 FDA approved drugs on human cells that expressed the enzyme. The screen identified five previously unknown CaMKII inhibitors; ruxolitinib, which is used to treat cancers of the blood and bone marrow, along with skin conditions like atopic dermatitis and vitiligo, was the most effective. Thu, 22 Jun 2023 18:28:28 EDT //www.koonmotors.com/releases/2023/06/230622182828.htm //www.koonmotors.com/releases/2023/06/230612200436.htm A decade after scientists identified an over-the-counter antihistamine as a treatment for multiple sclerosis, researchers have developed an approach to measure the drug's effectiveness in repairing the brain, making it possible to also assess future therapies for the devastating disorder. Mon, 12 Jun 2023 20:04:36 EDT //www.koonmotors.com/releases/2023/06/230612200436.htm //www.koonmotors.com/releases/2023/06/230609125736.htm A model known as ConPLex can predict whether potential drug molecules will interact with specific protein targets, without having to perform the computationally intensive calculation of the molecules' structures. By applying a language model to protein-drug interactions, researchers can quickly screen large libraries of potential drug compounds. Fri, 09 Jun 2023 12:57:36 EDT //www.koonmotors.com/releases/2023/06/230609125736.htm //www.koonmotors.com/releases/2023/06/230608121022.htm 有没有想过药物达到圆盾ts and achieve their function within our bodies? If a drug molecule or a ligand is a message, an inbox is typically a receptor in the cell membrane. One such receptor involved in relaying molecular signals is a G protein-coupled receptor (GPCR). About one-third of existing drugs work by controlling the activation of this protein. Researchers now reveal a new way of activating GPCR by triggering shape changes in the intracellular region of the receptor. This new process can help researchers design drugs with fewer or no side effects. Thu, 08 Jun 2023 12:10:22 EDT //www.koonmotors.com/releases/2023/06/230608121022.htm //www.koonmotors.com/releases/2023/06/230601182921.htm The results of a new clinical trial suggest that the first drug therapy to slow the progression of nearsightedness in kids could be on the horizon. The three-year study found that a daily drop in each eye of a low dose of atropine, a drug used to dilate pupils, was better than a placebo at limiting eyeglass prescription changes and inhibiting elongation of the eye in nearsighted children aged 6 to 10. Thu, 01 Jun 2023 18:29:21 EDT //www.koonmotors.com/releases/2023/06/230601182921.htm //www.koonmotors.com/releases/2023/06/230601160147.htm Health professionals are in urgent need of new antibiotics to tackle resistant bacteria. Researchers have now modified the chemical structure of naturally occurring peptides to develop antimicrobial molecules that bind to novel targets in the bacteria's metabolism. Thu, 01 Jun 2023 16:01:47 EDT //www.koonmotors.com/releases/2023/06/230601160147.htm //www.koonmotors.com/releases/2023/05/230531150050.htm Chemists add another powerful tool to their 'molecular editing' toolkit for crafting pharmaceuticals and other valuable compounds. Wed, 31 May 2023 15:00:50 EDT //www.koonmotors.com/releases/2023/05/230531150050.htm //www.koonmotors.com/releases/2023/05/230530174302.htm While it can take years for the pharmaceutical industry to create medicines capable of treating or curing human disease, a new study suggests that using generative artificial intelligence could vastly accelerate the drug-development process. Tue, 30 May 2023 17:43:02 EDT //www.koonmotors.com/releases/2023/05/230530174302.htm //www.koonmotors.com/releases/2023/05/230525141523.htm Using AI, researchers identified a new antibiotic that can kill Acinetobacter baumannii, a type of bacteria that is responsible for many drug-resistant infections. Thu, 25 May 2023 14:15:23 EDT //www.koonmotors.com/releases/2023/05/230525141523.htm //www.koonmotors.com/releases/2023/05/230524181908.htm Recent research has identified a new compound that can stimulate nerve regeneration after injury, as well as protect cardiac tissue from the sort of damage seen in heart attack. Wed, 24 May 2023 18:19:08 EDT //www.koonmotors.com/releases/2023/05/230524181908.htm //www.koonmotors.com/releases/2023/05/230511164501.htm Chemists devise a new, C-H activation-based method for the synthesis of BCBs. Thu, 11 May 2023 16:45:01 EDT //www.koonmotors.com/releases/2023/05/230511164501.htm //www.koonmotors.com/releases/2023/05/230504121035.htm Proteins that act like air traffic controllers, managing the flow of signals in and out of human cells, have been observed for the first time with unprecedented detail using advanced microscopy techniques. New findings could inform the development of better drugs for pain relief, diabetes or heart failure. Thu, 04 May 2023 12:10:35 EDT //www.koonmotors.com/releases/2023/05/230504121035.htm //www.koonmotors.com/releases/2023/05/230503121257.htm Immunotherapy has redefined cancer treatment, but not all patients experience the same benefit when treated. New research in mice identifies how gut bacteria alter the body's response to a common form of cancer immunotherapy. The animals' gut microbiota lowered the expression of two immune molecules, one previously unknown to play a role in cancer. • Using antibodies to block the activity of either molecule, or the interplay between them, enhanced response to cancer immunotherapy. • The findings can inform the design of treatments that boost the efficacy of cancer immunotherapy among patients with suboptimal response. Wed, 03 May 2023 12:12:57 EDT //www.koonmotors.com/releases/2023/05/230503121257.htm //www.koonmotors.com/releases/2023/04/230427173549.htm A new test revealed that FDA-approved antibiotics -- available at your neighborhood pharmacy -- can effectively treat superbugs. They are not prescribed, however, because the gold-standard test predicts they will not work. The new test may improve the way antibiotics are developed, tested and prescribed -- and it is openly available to all. Thu, 27 Apr 2023 17:35:49 EDT //www.koonmotors.com/releases/2023/04/230427173549.htm //www.koonmotors.com/releases/2023/04/230425111215.htm A new trial has found a new genetic therapy for Alzheimer's disease that is able to safely and successfully lower levels of the harmful tau protein known to cause the disease. Tue, 25 Apr 2023 11:12:15 EDT //www.koonmotors.com/releases/2023/04/230425111215.htm //www.koonmotors.com/releases/2023/04/230424133548.htm A research team has shown in early tests that a bioengineered drug candidate can counter infection with Staphylococcus aureus -- a bacterial species widely resistant to antibiotics. Mon, 24 Apr 2023 13:35:48 EDT //www.koonmotors.com/releases/2023/04/230424133548.htm //www.koonmotors.com/releases/2023/04/230424103345.htm Despite the promise of new medications that promote cancer cell death in people with acute myeloid leukemia, leukemic cells often adopt features that let them evade the drugs' effects within a year. 星期一,2023年4月24日10:33:45 EDT //www.koonmotors.com/releases/2023/04/230424103345.htm //www.koonmotors.com/releases/2023/04/230419142749.htm Researchers find that when immunostimulatory drugs called imidazoquinolines are delivered using specialized bottlebrush nanoparticles, the drugs provoke the immune system to attack tumors while eliminating the side effects that occur when the drugs are given on their own. Wed, 19 Apr 2023 14:27:49 EDT //www.koonmotors.com/releases/2023/04/230419142749.htm //www.koonmotors.com/releases/2023/04/230419125104.htm Scientists have designed a new type of oral capsule that could mean pain-free delivery of insulin and other protein drugs. Protein drugs had proven challenging to deliver orally as the drugs degrade very quickly in the stomach -- until now. Wed, 19 Apr 2023 12:51:04 EDT //www.koonmotors.com/releases/2023/04/230419125104.htm