//www.koonmotors.com/news/health_medicine/parkinson's_disease/ Latest medical research on Parkinson's disease. Learn about Parkinson's disease treatments, symptoms, medication and more. en-us Wed, 06 Sep 2023 14:46:21 EDT Wed, 06 Sep 2023 14:46:21 EDT 60 //www.koonmotors.com/images/scidaily-logo-rss.png//www.koonmotors.com/news/health_medicine/parkinson's_disease/ For more science news, visit ScienceDaily. //www.koonmotors.com/releases/2023/08/230830151801.htm A massive study of medical and genetic data shows that people with a particular version of a gene involved in immune response had a lower risk of Alzheimer's and Parkinson's disease. Wed, 30 Aug 2023 15:18:01 EDT //www.koonmotors.com/releases/2023/08/230830151801.htm //www.koonmotors.com/releases/2023/08/230830151742.htm 研究人员发明了一种血液测试,发现ts Parkinson's disease, potentially establishing a way to help diagnose the condition before nervous system damage worsens. A new blood-based diagnostic test would be a major advancement for Parkinson's disease, which afflicts 10 million people worldwide and is the second-most common neurodegenerative disease after Alzheimer's. Wed, 30 Aug 2023 15:17:42 EDT //www.koonmotors.com/releases/2023/08/230830151742.htm //www.koonmotors.com/releases/2023/08/230822151748.htm Many researchers believe that the neurodegenerative disorder gets started in the gut. Research now suggests that an autoimmune reaction may be driving those early events. Tue, 22 Aug 2023 15:17:48 EDT //www.koonmotors.com/releases/2023/08/230822151748.htm //www.koonmotors.com/releases/2023/08/230821174246.htm Markers that indicate the presence of Parkinson's disease in patients on average seven years before clinical presentation have been identified by a UCL and Moorfields Eye Hospital research team. Mon, 21 Aug 2023 17:42:46 EDT //www.koonmotors.com/releases/2023/08/230821174246.htm //www.koonmotors.com/releases/2023/08/230811115422.htm Identification of risk factors for Parkinson's disease (PD) is essential for early diagnosis. Dating back to the 1920s, Parkinson's disease and parkinsonism -- an umbrella term that refers to motor symptoms found in Parkinson's disease and also other conditions -- have long been described in boxers. Repetitive head impacts from tackle football can also have long-term neurological consequences like chronic traumatic encephalopathy (CTE). But research on the association between participation in tackle football and PD is limited. Fri, 11 Aug 2023 11:54:22 EDT //www.koonmotors.com/releases/2023/08/230811115422.htm //www.koonmotors.com/releases/2023/08/230809164716.htm In Parkinson's disease, growing evidence targets neuroinflammation as essential for brain pathogenesis. But which group of immune cells that reside in the brain direct this inflammatory response? Scientists used a mouse model of Parkinson's disease to show that border-associated macrophages -- not microglia -- mediate the neuroinflammatory response in the brain. Wed, 09 Aug 2023 16:47:16 EDT //www.koonmotors.com/releases/2023/08/230809164716.htm //www.koonmotors.com/releases/2023/08/230809130726.htm Researchers have developed a technique for simultaneously measuring electrical signals from 128 areas of the brain in awake rats. They have then used the information to measure what happens to the neurons when the rats are given psychedelic drugs. The results show an unexpected and simultaneous synchronization among neurons in several regions of the brain. Wed, 09 Aug 2023 13:07:26 EDT //www.koonmotors.com/releases/2023/08/230809130726.htm //www.koonmotors.com/releases/2023/08/230808110953.htm Gait-related disturbances adversely affect the quality of life of patients with Parkinson's disease (PD), a condition affecting millions worldwide. Although various pharmacological, surgical, and rehabilitative treatments exist, their effectiveness is limited. Now, a team of researchers has successfully addressed this limitation. Using a novel neuromodulation approach that incorporates gait-combined closed-loop transcranial electrical stimulation, the team demonstrated significant gait improvements in patients with various neurological disorders including PD. Tue, 08 Aug 2023 11:09:53 EDT //www.koonmotors.com/releases/2023/08/230808110953.htm //www.koonmotors.com/releases/2023/08/230803113012.htm Although there is a long-standing, common assumption that most -- if not all -- dopamine neurons solely respond to rewards or reward-predicting cues, researchers instead discovered that one genetic subtype fires when the body moves and does not respond to rewards at all. The discovery could help explain why loss of dopamine neurons leads to Parkinson's disease. Thu, 03 Aug 2023 11:30:12 EDT //www.koonmotors.com/releases/2023/08/230803113012.htm //www.koonmotors.com/releases/2023/07/230727144133.htm A group of nerve cells in the brain has the remarkable ability to completely stop all forms of movement, a new mouse study shows. The discovery provides valuable insight into how the nervous system can control our movements. Thu, 27 Jul 2023 14:41:33 EDT //www.koonmotors.com/releases/2023/07/230727144133.htm //www.koonmotors.com/releases/2023/07/230719150009.htm A new discovery paves the way for clinical trials that use patients' own cells to treat Parkinson's disease. Wed, 19 Jul 2023 15:00:09 EDT //www.koonmotors.com/releases/2023/07/230719150009.htm //www.koonmotors.com/releases/2023/07/230719145938.htm Scientists have uncovered a new mechanism by which mutations in a gene parkin contribute to familial forms of Parkinson's disease. The discovery opens a new avenue for Parkinson's therapeutics, scientists report in a new study. They discovered that mutations in parkin result in a breakdown of contacts between two key workers in the cell -- lysosomes and mitochondria. Wed, 19 Jul 2023 14:59:38 EDT //www.koonmotors.com/releases/2023/07/230719145938.htm //www.koonmotors.com/releases/2023/07/230718164245.htm 路易是第二个最常见的neurod身体疾病egenerative disease after Alzheimer's disease. A research group has now shown that the disease can be detected before symptoms appear, using a spinal fluid test. Researchers also demonstrate that reduced sense of smell is strongly linked to Lewy body disease even before other clear symptoms have developed. Tue, 18 Jul 2023 16:42:45 EDT //www.koonmotors.com/releases/2023/07/230718164245.htm //www.koonmotors.com/releases/2023/07/230712124631.htm Researchers have demonstrated that a transplant surgical procedure (called 'needle trauma') triggers a profound immune response and causes the death of most grafted dopamine neurons. They also found that co-transplantation of neuronal cell therapy with host regulatory T cells resulted in effective suppression of needle trauma and significant improvement in the survival and recovery of grafts. These findings suggest a path for the 'realistic' use of cell therapy to treat neurodegenerative disorders. Wed, 12 Jul 2023 12:46:31 EDT //www.koonmotors.com/releases/2023/07/230712124631.htm //www.koonmotors.com/releases/2023/06/230627225220.htm Researchers have solved a long-standing mystery about how a protein helps rid the body of damaged mitochondria, in findings that could help lead to potential new treatments for Parkinson's disease. Tue, 27 Jun 2023 22:52:20 EDT //www.koonmotors.com/releases/2023/06/230627225220.htm //www.koonmotors.com/releases/2023/05/230518120851.htm Through a novel pairing of epidemiology and toxicity screening, researchers were able to identify 10 pesticides that were directly toxic to key neurons. Thu, 18 May 2023 12:08:51 EDT //www.koonmotors.com/releases/2023/05/230518120851.htm //www.koonmotors.com/releases/2023/05/230516115542.htm Two years of heavy exposure to TCE, a liquid chemical that lingers in the air, water and soil, may increase the risk of Parkinson's disease by 70%. Tue, 16 May 2023 11:55:42 EDT //www.koonmotors.com/releases/2023/05/230516115542.htm //www.koonmotors.com/releases/2023/04/230420110141.htm Scientists have identified a protein-protein interaction that contributes to Parkinson's disease. Thu, 20 Apr 2023 11:01:41 EDT //www.koonmotors.com/releases/2023/04/230420110141.htm //www.koonmotors.com/releases/2023/04/230412131051.htm 多巴胺,一种大脑化学物质长期与pl相关联easure, motivation and reward-seeking, also appears to play an important role in why exercise and other physical efforts feel 'easy' to some people and exhausting to others, according to results of a study of people with Parkinson's disease. Parkinson's disease is marked by a loss of dopamine-producing cells in the brain over time. Wed, 12 Apr 2023 13:10:51 EDT //www.koonmotors.com/releases/2023/04/230412131051.htm //www.koonmotors.com/releases/2023/03/230322190926.htm Changes in the brain caused by Alzheimer's disease are associated with shortening of the telomeres -- the protective caps on the ends of chromosomes that shorten as cells age -- according to a new study. Wed, 22 Mar 2023 19:09:26 EDT //www.koonmotors.com/releases/2023/03/230322190926.htm //www.koonmotors.com/releases/2023/03/230303105344.htm The words that researchers use to describe their results can be harnessed to discover potential new treatments for Parkinson's disease, according to a new study. The study employed an artificial intelligence (AI) system to identify an existing anti-cholesterol drug that has the ability to promote the disposal of mitochondria, energy-making components of the cell which are damaged in the disease. Fri, 03 Mar 2023 10:53:44 EST //www.koonmotors.com/releases/2023/03/230303105344.htm //www.koonmotors.com/releases/2023/02/230228205244.htm Researchers have identified gut bacteria that are associated with dementia with Lewy bodies. Changing the levels of three bacteria, Collinsella, Ruminococcus, and Bifidobacterium, may delay the onset and progression of this neurodegenerative disease. Tue, 28 Feb 2023 20:52:44 EST //www.koonmotors.com/releases/2023/02/230228205244.htm //www.koonmotors.com/releases/2023/02/230216161943.htm The so-called isolated REM-sleep behavior disorder is a condition that can provide an indication of Parkinson's disease well in advance. Thu, 16 Feb 2023 16:19:43 EST //www.koonmotors.com/releases/2023/02/230216161943.htm //www.koonmotors.com/releases/2023/01/230124103835.htm 研究人员试图确定早期症状啊f Parkinson's disease using voice data. In their study, the researchers used artificial intelligence (AI) to analyze and assess speech signals, where calculations are done and diagnoses made in seconds rather than hours. Tue, 24 Jan 2023 10:38:35 EST //www.koonmotors.com/releases/2023/01/230124103835.htm //www.koonmotors.com/releases/2023/01/230120130916.htm Neuroscientists find two distinct cell populations in the striatum are affected differently by Huntington's disease. They believe neurodegeneration of one of these populations leads to motor impairments, while damage to the other population, located in a structure called the striosome, may account for the mood disorders that are often see in the early stages of the disease. Fri, 20 Jan 2023 13:09:16 EST //www.koonmotors.com/releases/2023/01/230120130916.htm //www.koonmotors.com/releases/2023/01/230110191417.htm 新的研究肠道微生物组是涉及我说n multiple pathways in the pathogenesis of Parkinson's disease. The findings show a wide imbalance in microbiome composition in persons with Parkinson's disease. The investigators employed metagenomics, the study of genetic material recovered directly from the stool microbiome of persons with PD and neurologically healthy control subjects. Tue, 10 Jan 2023 19:14:17 EST //www.koonmotors.com/releases/2023/01/230110191417.htm //www.koonmotors.com/releases/2022/12/221213094812.htm New findings from mechanical engineers could, one day, help doctors screen patients for illnesses like depression or Parkinson's Disease. Tue, 13 Dec 2022 09:48:12 EST //www.koonmotors.com/releases/2022/12/221213094812.htm //www.koonmotors.com/releases/2022/11/221128101246.htm Researchers have found that a set of proteins have different shapes in the spinal fluid of healthy individuals and Parkinson's patients. These could be used in the future as a new type of biomarker for this disease. Mon, 28 Nov 2022 10:12:46 EST //www.koonmotors.com/releases/2022/11/221128101246.htm //www.koonmotors.com/releases/2022/11/221117102811.htm 线粒体主要强国of the cell. However, these cellular organelles are required not only for providing energy: Researchers recently discovered that mitochondria play an important role in signal transduction in innate immune pathways. They regulate a signalling pathway that helps to eliminate pathogens, but can cause damage through inflammation upon overactivation. Thu, 17 Nov 2022 10:28:11 EST //www.koonmotors.com/releases/2022/11/221117102811.htm //www.koonmotors.com/releases/2022/11/221116164916.htm People with neurologic diseases like headache, dementia, multiple sclerosis (MS) and Parkinson's disease may experience worsening symptoms due to climate change, according to a scoping review of research. The review also found that stroke may become more prevalent due to climate change. Wed, 16 Nov 2022 16:49:16 EST //www.koonmotors.com/releases/2022/11/221116164916.htm //www.koonmotors.com/releases/2022/11/221115114023.htm Water -- which makes up the majority of every cell in the body -- plays a key role in how proteins, including those associated with Parkinson's disease, fold, misfold, or clump together, according to a new study. Tue, 15 Nov 2022 11:40:23 EST //www.koonmotors.com/releases/2022/11/221115114023.htm //www.koonmotors.com/releases/2022/11/221110114303.htm A team has developed a new tool that can predict how Parkinson's disease patients will fare over the course of a year based on their genetics, brain scans and physical examinations. Thu, 10 Nov 2022 11:43:03 EST //www.koonmotors.com/releases/2022/11/221110114303.htm //www.koonmotors.com/releases/2022/11/221109124330.htm Researchers have discovered that the neurotransmitter adenosine effectively acts as a brake to dopamine, another well-known neurotransmitter involved in motor control. The discovery could immediately suggest new avenues of drug development to treat symptoms of Parkinson's disease, a movement disorder where the loss of dopamine-producing cells has been widely implicated as a cause. Wed, 09 Nov 2022 12:43:30 EST //www.koonmotors.com/releases/2022/11/221109124330.htm //www.koonmotors.com/releases/2022/11/221108120444.htm Parkinson's disease affects 3% of population over 65 years old, and the average age of onset is 60. Regarding juvenile Parkinson, which represents the rest of all Parkison's cases, the disease begins before 40 years old. Now, a group of researchers has deciphered the molecular mechanism by which a mutation of the adenosine type 1 receptor gene is associated with juvenile Parkinson's. Tue, 08 Nov 2022 12:04:44 EST //www.koonmotors.com/releases/2022/11/221108120444.htm //www.koonmotors.com/releases/2022/11/221103140754.htm A new treatment for neurological and psychiatric diseases, that works by reducing the excitability of overactive brain cells, has been developed. Thu, 03 Nov 2022 14:07:54 EDT //www.koonmotors.com/releases/2022/11/221103140754.htm //www.koonmotors.com/releases/2022/11/221101100735.htm Researchers have found that COVID-19 activates the same inflammatory response in the brain as Parkinson's disease. The discovery identified a potential future risk for neurodegenerative conditions in people who've had COVID-19, but also a possible treatment. Tue, 01 Nov 2022 10:07:35 EDT //www.koonmotors.com/releases/2022/11/221101100735.htm //www.koonmotors.com/releases/2022/10/221019172137.htm People who gain or lose weight soon after being diagnosed with Parkinson's disease may be more likely to have changes in their thinking skills than people who maintain their weight, according to a new study. Wed, 19 Oct 2022 17:21:37 EDT //www.koonmotors.com/releases/2022/10/221019172137.htm //www.koonmotors.com/releases/2022/10/221005111946.htm A new screening test app could help advance the early detection of Parkinson's disease and severe COVID-19, improving the management of these illnesses. Developed by a research team of engineers and neurologists, the test can produce accurate results using just people's voice recordings. Wed, 05 Oct 2022 11:19:46 EDT //www.koonmotors.com/releases/2022/10/221005111946.htm //www.koonmotors.com/releases/2022/09/220922124408.htm A comprehensive analysis of federal data shows people who have had COVID-19 are at an elevated risk of developing neurological conditions within the first year after infection. Movement disorders, memory problems, strokes and seizures are among the complications. Thu, 22 Sep 2022 12:44:08 EDT //www.koonmotors.com/releases/2022/09/220922124408.htm //www.koonmotors.com/releases/2022/09/220921141459.htm Researchers can track the severity and progression of Parkinson's disease, as well as how a patient responds to medication, using an in-home device that passively monitors the patient's gait speed by bouncing radio signals off their body. Wed, 21 Sep 2022 14:14:59 EDT //www.koonmotors.com/releases/2022/09/220921141459.htm //www.koonmotors.com/releases/2022/09/220920154748.htm Aggregates of the protein alpha-synuclein spread in the brains of people with Parkinson's disease through a cellular waste-ejection process, suggests a new study. Tue, 20 Sep 2022 15:47:48 EDT //www.koonmotors.com/releases/2022/09/220920154748.htm //www.koonmotors.com/releases/2022/09/220915142440.htm Infections treated with specialty hospital care in early- and mid-life are associated with an increased subsequent risk of Alzheimer's (AD) and Parkinson's diseases (PD), but not amyotrophic lateral sclerosis (ALS), according to a new study. Thu, 15 Sep 2022 14:24:40 EDT //www.koonmotors.com/releases/2022/09/220915142440.htm //www.koonmotors.com/releases/2022/09/220912112423.htm Researchers have shown that a hormone secreted into the blood during endurance, or aerobic, exercise reduces levels of a protein linked to Parkinson's disease and halts movement problems in mice. Mon, 12 Sep 2022 11:24:23 EDT //www.koonmotors.com/releases/2022/09/220912112423.htm //www.koonmotors.com/releases/2022/08/220830135635.htm Scientists have uncovered how a build-up of harmful protein starts to happen within neurons in Parkinson's disease, ultimately causing nerve cell death. By looking at how, where and why this build-up happens, the work provides unique insight into a key biological process driving Parkinson's. Tue, 30 Aug 2022 13:56:35 EDT //www.koonmotors.com/releases/2022/08/220830135635.htm //www.koonmotors.com/releases/2022/08/220829112912.htm Inactivation of a particular protein complex that plays a key role in keeping genes switched off leads to nerve cells not producing enough essential neurotransmitters. This could be part of the explanation for diseases such as Parkinson's as well as anxiety disorders. Mon, 29 Aug 2022 11:29:12 EDT //www.koonmotors.com/releases/2022/08/220829112912.htm //www.koonmotors.com/releases/2022/08/220825120322.htm A device with the appearance of a Wi-Fi router uses a neural network to discern the presence and severity of one of the fastest-growing neurological diseases in the world. Thu, 25 Aug 2022 12:03:22 EDT //www.koonmotors.com/releases/2022/08/220825120322.htm //www.koonmotors.com/releases/2022/08/220817103959.htm Researchers have developed a new method for studying age-related brain disorders. The researchers have focused on the neurodegenerative disorder Huntington's disease. Wed, 17 Aug 2022 10:39:59 EDT //www.koonmotors.com/releases/2022/08/220817103959.htm //www.koonmotors.com/releases/2022/08/220801133137.htm Researchers report that individuals with two copies of a gene mutation show evidence of substantial iron buildup in regions of the brain, raising risk for movement disorders like Parkinson's disease. Mon, 01 Aug 2022 13:31:37 EDT //www.koonmotors.com/releases/2022/08/220801133137.htm //www.koonmotors.com/releases/2022/08/220801133128.htm Researchers have identified a group of molecules that enable cells to repair damaged components, making it possible for those tissues to retain proper function. Mon, 01 Aug 2022 13:31:28 EDT //www.koonmotors.com/releases/2022/08/220801133128.htm //www.koonmotors.com/releases/2022/07/220726132536.htm Researchers have produced definitive evidence that a specific region in the brain, called the subthalamic nucleus, is critical to governing the mind's communication with the body's motor control system. The findings, stemming from innovative experiments with humans, could yield advances in treatment for Parkinson's disease. Tue, 26 Jul 2022 13:25:36 EDT //www.koonmotors.com/releases/2022/07/220726132536.htm //www.koonmotors.com/releases/2022/07/220715151014.htm Cellular changes in Parkinson's could be revealed by adapting a related technique, known as quantitative MRI (qMRI). A new method enabled researchers to look at microstructures within the part of the deep brain known as the striatum -- an organ which is known to deteriorate during the progress of Parkinson's disease. With a novel method of analysis, biological changes in the cellar tissue of the striatum were clearly revealed and the team was able to demonstrate that these changes were associated with the early stages of Parkinson's and patients' movement dysfunction. Fri, 15 Jul 2022 15:10:14 EDT //www.koonmotors.com/releases/2022/07/220715151014.htm //www.koonmotors.com/releases/2022/07/220713152848.htm Researchers are a step closer to understanding how Parkinson's disease develops and progresses thanks to chemical biological tools. Wed, 13 Jul 2022 15:28:48 EDT //www.koonmotors.com/releases/2022/07/220713152848.htm //www.koonmotors.com/releases/2022/07/220713143947.htm A team of researchers has linked neuronal activity to the levels of sphingolipids, a type of fat, in brain cells. Furthermore, disruption of sphingolipid metabolism led to significant neuronal damage and neurodegeneration in animal models, revealing a new molecular perspective to the cause of Gaucher's disease. Wed, 13 Jul 2022 14:39:47 EDT //www.koonmotors.com/releases/2022/07/220713143947.htm //www.koonmotors.com/releases/2022/07/220707141904.htm Copper exposure in the environment and the protein alpha-synuclein in the human brain could play an important role in the pathogenesis of Parkinson's disease. Researchers were able to show how the protein takes on an unusual shape when exposed to large amounts of copper ions. The findings could help develop new strategies for the treatment of neurodegenerative diseases. Thu, 07 Jul 2022 14:19:04 EDT //www.koonmotors.com/releases/2022/07/220707141904.htm //www.koonmotors.com/releases/2022/06/220609130022.htm One of the hallmarks of Parkinson's disease (PD) is the accumulation in the brain of a protein known as alpha-synuclein. A new study shines new light on the role of alpha-synuclein, uncovering a new function for the protein with relevance for PD and related conditions. The team's findings are published in Cell. Thu, 09 Jun 2022 13:00:22 EDT //www.koonmotors.com/releases/2022/06/220609130022.htm //www.koonmotors.com/releases/2022/06/220608112527.htm Neuroscientists identified three circuits in the thalamus that influence the development of motor and nonmotor symptoms of Parkinson's disease. And by manipulating these circuits, they could reverse Parkinson's symptoms in mice. Wed, 08 Jun 2022 11:25:27 EDT //www.koonmotors.com/releases/2022/06/220608112527.htm //www.koonmotors.com/releases/2022/06/220607194448.htm Older adults who start to experience bad dreams or nightmares could be exhibiting the earliest signs of Parkinson's disease, say researchers. Tue, 07 Jun 2022 19:44:48 EDT //www.koonmotors.com/releases/2022/06/220607194448.htm //www.koonmotors.com/releases/2022/06/220601092215.htm Researchers have successfully developed a biomarker that will enable Parkinson's disease to be rapidly and inexpensively diagnosed from blood serum samples. Being able to diagnose the disease faster will hopefully lead to the development of new treatment methods, which will have great benefit, especially for aging societies. Wed, 01 Jun 2022 09:22:15 EDT //www.koonmotors.com/releases/2022/06/220601092215.htm //www.koonmotors.com/releases/2022/05/220524110655.htm Emotion-recognition among people with disorders such as Parkinson's disease or schizophrenia may be affected by changes in the levels dopamine in the brain, say researchers. Tue, 24 May 2022 11:06:55 EDT //www.koonmotors.com/releases/2022/05/220524110655.htm //www.koonmotors.com/releases/2022/05/220519132735.htm In studies with mouse and human tissue, as well as live mice, researchers report that a snag in the normal process of cleaning up broken DNA in brain cells may hasten the progression of Parkinson's disease. Specifically, the researchers found that a protein dubbed 'STING' responds to clean-up signals in brain cells damaged by Parkinson's disease by creating a cycle of inflammation that may accelerate the disease's progression. Thu, 19 May 2022 13:27:35 EDT //www.koonmotors.com/releases/2022/05/220519132735.htm