Pain Control News -- ScienceDaily //www.koonmotors.com/news/health_medicine/pain_control/ Pain Management and Pain Control. Read about causes of aches and pains and breaking news on conventional and alternative pain control methods. en-us Sun, 10 Sep 2023 11:48:05 EDT Sun, 10 Sep 2023 11:48:05 EDT 60 Pain Control News -- ScienceDaily //www.koonmotors.com/images/scidaily-logo-rss.png//www.koonmotors.com/news/health_medicine/pain_control/ For more science news, visit ScienceDaily. Insomnia drug helps prevent oxycodone relapse //www.koonmotors.com/releases/2023/09/230906135638.htm New findings suggest that treating insomnia can stop opioid-seeking behavior, even after ending treatment. Wed, 06 Sep 2023 13:56:38 EDT //www.koonmotors.com/releases/2023/09/230906135638.htm 'Gates of Heaven' calcium channel drives oral cancer pain and growth //www.koonmotors.com/releases/2023/09/230905155711.htm An essential protein that acts as a gatekeeper for calcium entering cells promotes the growth of oral cancer and generates pain, according to a new study. Targeting this protein -- the ORAI1 calcium channel -- could provide a new approach to treating oral cancer, which causes persistent pain that worsens as it progresses. Tue, 05 Sep 2023 15:57:11 EDT //www.koonmotors.com/releases/2023/09/230905155711.htm New study shows effectiveness of mpox vaccine //www.koonmotors.com/releases/2023/09/230905124929.htm A new international study has shown mpox (formerly known as monkeypox) infections to be less severe among those who are vaccinated or had a previous infection in 2022, underlining the importance and effectiveness of vaccination. Tue, 05 Sep 2023 12:49:29 EDT //www.koonmotors.com/releases/2023/09/230905124929.htm Women more severely affected by chronic fatigue syndrome //www.koonmotors.com/releases/2023/08/230824111857.htm Women with ME/CFS tend to have more symptoms and co-occurring conditions than men, according to initial results from the world's largest study of the disease. It has long been known that women are more likely to have ME/CFS (myalgic encephalomyelitis/chronic fatigue syndrome) but the DecodeME study has shown for the first time how their experience differs from men. Thu, 24 Aug 2023 11:18:57 EDT //www.koonmotors.com/releases/2023/08/230824111857.htm New study reveals the most common form of arthritis, osteoarthritis, affects 15% of the global population over the age of 30 //www.koonmotors.com/releases/2023/08/230821232429.htm Mon, 21 Aug 2023 23:24:29 EDT //www.koonmotors.com/releases/2023/08/230821232429.htm Raising awareness of Long Covid 'blue legs' symptom //www.koonmotors.com/releases/2023/08/230812001828.htm An unusual case of a Long Covid patient's legs turning blue after 10 minutes of standing highlights the need for greater awareness of this symptom among people with the condition, according to new research. Sat, 12 Aug 2023 00:18:28 EDT //www.koonmotors.com/releases/2023/08/230812001828.htm Symptoms of the body and the mind are frequent fellow travelers //www.koonmotors.com/releases/2023/08/230807121902.htm Chronic pain is often accompanied by depression and anxiety. Experts discuss the relationship between pain, the most common symptom for which individuals visit a physician, and depression and anxiety, the two most prevalent mental health conditions worldwide. Noting the existence of a feedback loop, experts highlight the importance of not neglecting psychological symptoms in patients experiencing pain. Mon, 07 Aug 2023 12:19:02 EDT //www.koonmotors.com/releases/2023/08/230807121902.htm How the gut signals to the brain //www.koonmotors.com/releases/2023/08/230803113020.htm Scientists define five types of colon neurons specialized for sending different signals to the brain. Thu, 03 Aug 2023 11:30:20 EDT //www.koonmotors.com/releases/2023/08/230803113020.htm Scrambler therapy may offer lasting relief for chronic pain, review paper suggests //www.koonmotors.com/releases/2023/07/230731122236.htm Pain experts suggest that scrambler therapy, a noninvasive pain treatment, can yield significant relief for approximately 80% -- 90% of patients with chronic pain, and it may be more effective than another noninvasive therapy: transcutaneous electrical nerve stimulation (TENS). Mon, 31 Jul 2023 12:22:36 EDT //www.koonmotors.com/releases/2023/07/230731122236.htm Gene therapy treats chronic pain by dialing down sodium //www.koonmotors.com/releases/2023/07/230727212040.htm Scientists identified the region where a protein regulates sodium ion channels, inserting the channel's genetic material into a virus to alleviate pain in cell and animal studies. Thu, 27 Jul 2023 21:20:40 EDT //www.koonmotors.com/releases/2023/07/230727212040.htm Researchers use the antidepressant tianeptine to manage chronic pain //www.koonmotors.com/releases/2023/07/230724122651.htm Neuropathic pain is a debilitating condition estimated to affect as much as 10% of the global population. It results from a damaged or malfunctioning nervous system, stemming from diseases like diabetes, alcoholism, strokes, Parkinson's and other causes like spinal nerve compression, radiation and chemotherapy treatments. Management of neuropathic pain has been particularly challenging as currently prescribed drugs, such as anticonvulsants and antidepressants can have severe adverse effects, are not well-tolerated, take a longer time to work only help a subset of patients. Mon, 24 Jul 2023 12:26:51 EDT //www.koonmotors.com/releases/2023/07/230724122651.htm Children's IQs not diminished by concussion, study suggests //www.koonmotors.com/releases/2023/07/230717115826.htm 一项新的研究发现脑震荡不降低智商of children. Findings may help to reduce parental fears regarding these common and concerning head injuries. Researchers looked at socioeconomic status, patient sex, severity of injuries, concussion history, and whether there was a loss of consciousness at the time of injury. None of these factors made a difference. Across the board, concussion was not associated with lower IQ. Mon, 17 Jul 2023 11:58:26 EDT //www.koonmotors.com/releases/2023/07/230717115826.htm People generalize expectations of pain to conceptually related tasks //www.koonmotors.com/releases/2023/07/230712124708.htm Avoiding experiences associated with pain can be an adaptive behavior, but generalized avoidance can become problematic, even potentially culminating in disability. Wed, 12 Jul 2023 12:47:08 EDT //www.koonmotors.com/releases/2023/07/230712124708.htm Pain risk varies significantly across states //www.koonmotors.com/releases/2023/07/230707124648.htm The prevalence of moderate or severe joint pain due to arthritis varies strikingly across American states, ranging from 6.9% of the population in Minnesota to 23.1% in West Virginia, according to a new study. Fri, 07 Jul 2023 12:46:48 EDT //www.koonmotors.com/releases/2023/07/230707124648.htm New AI tool beats standard approaches for detecting heart attacks //www.koonmotors.com/releases/2023/06/230629125710.htm A new machine learning model uses electrocardiogram (ECG) readings to diagnose and classify heart attacks faster and more accurately than current approaches, according to a new study. Thu, 29 Jun 2023 12:57:10 EDT //www.koonmotors.com/releases/2023/06/230629125710.htm Lupus flare-ups strongly linked to specific bacterial growth in gut //www.koonmotors.com/releases/2023/06/230627225150.htm Recurrent bouts of systemic lupus erythematosus, marked by the body's immune system attack of its own tissues, closely tracked with measureable upticks in growth in the gut of a certain species of bacteria. Tue, 27 Jun 2023 22:51:50 EDT //www.koonmotors.com/releases/2023/06/230627225150.htm Body's immune response may offer alternative approach to neuropathic pain therapies //www.koonmotors.com/releases/2023/06/230627123030.htm In the midst of a global opioid epidemic, a team of scientists is exploring natural killer (NK) cells as an alternative treatment for neuropathic pain. Researchers gather existing evidence for the impact of NK cells in pain, pointing to their ability to prune the damaged nerve cells that may cause it. They urge the scientific community to explore biological mechanisms underlying NK cell activity to move towards a realistic pain therapy that is both effective and safe. Tue, 27 Jun 2023 12:30:30 EDT //www.koonmotors.com/releases/2023/06/230627123030.htm Pain not perceived in the same way in people with Alzheimer's Disease //www.koonmotors.com/releases/2023/06/230622120855.htm New research has found that in a mouse model mimicking Alzheimer's Disease (AD) pain signals are not processed in the same way as in healthy mice. Thu, 22 Jun 2023 12:08:55 EDT //www.koonmotors.com/releases/2023/06/230622120855.htm Everyone's brain has a pain fingerprint -- new research has revealed for the first time //www.koonmotors.com/releases/2023/06/230620113739.htm New research has revealed everyone's brain has a 'pain fingerprint' that varies from person to person. 星期二,6月2023 11:37:39美国东部时间 //www.koonmotors.com/releases/2023/06/230620113739.htm New research identifies cells linking chronic psychological stress to inflammatory bowel disease //www.koonmotors.com/releases/2023/06/230608195659.htm For the first time, cells involved with the communication between stress responses in the brain and inflammation in the gastrointestinal (GI) tract have been identified in animal models. Glial cells, which support neurons, communicate stress signals from the central nervous system (CNS) to the semi-autonomous nervous system within the gastrointestinal (GI) tract, called the enteric nervous system (ENS). These psychological stress signals can cause inflammation and exacerbate symptoms of inflammatory bowel disease (IBD). Thu, 08 Jun 2023 19:56:59 EDT //www.koonmotors.com/releases/2023/06/230608195659.htm Tiny video capsule shows promise as an alternative to endoscopy //www.koonmotors.com/releases/2023/06/230601160055.htm While ingestible video capsule endoscopes have been around for many years, the capsules have been limited by the fact that they could not be controlled by physicians. They moved passively, driven only by gravity and the natural movement of the body. Now, according to a new research study, physicians can remotely drive a miniature video capsule to all regions of the stomach to visualize and photograph potential problem areas. The new technology uses an external magnet and hand-held video game style joysticks to move the capsule in three-dimensions in the stomach. This new technology comes closer to the capabilities of a traditional tube-based endoscopy. Thu, 01 Jun 2023 16:00:55 EDT //www.koonmotors.com/releases/2023/06/230601160055.htm In 2050, over 800 million people globally estimated to be living with back pain //www.koonmotors.com/releases/2023/05/230523123745.htm Study estimates there will be over 800 million cases of low back pain in 2050, a 36 percent increase from 2020. With an aging population, researchers say we must 'put the brakes' on low back pain cases before the burden becomes too great for our healthcare system. Tue, 23 May 2023 12:37:45 EDT //www.koonmotors.com/releases/2023/05/230523123745.htm Brain signatures for chronic pain identified in a small group of individuals //www.koonmotors.com/releases/2023/05/230522131308.htm Researchers have recorded pain-related data from inside the brain of individuals with chronic pain disorders caused by stroke or amputation (phantom limb pain). A long sought-after goal has been to understand how pain is represented by brain activity and how to modulate that activity to relieve suffering from chronic pain. Data were collected over months while patients were at home, and they were analyzed using machine learning tools. Doing so, the researchers identified an area of the brain associated with chronic pain and objective biomarkers of chronic pain in individual patients. Mon, 22 May 2023 13:13:08 EDT //www.koonmotors.com/releases/2023/05/230522131308.htm Neuropathic pain: The underlying mechanism and a potential therapeutic target are revealed in mice //www.koonmotors.com/releases/2023/05/230504111839.htm Neuropathic pain -- abnormal hypersensitivity to stimuli -- is associated with impaired quality of life and is often poorly managed. Estimates suggest that 3 percent to 17 percent of adults suffer from neuropathic pain, including a quarter of people with diabetes and a third of people with HIV. Researchers report that a mechanism involving the enzyme Tiam1 in dorsal horn excitatory neurons of the spinal cord both initiates and maintains neuropathic pain. Moreover, they show that targeting spinal Tiam1 with anti-sense oligonucleotides injected into the cerebrospinal fluid effectively alleviated neuropathic pain hypersensitivity. Thu, 04 May 2023 11:18:39 EDT //www.koonmotors.com/releases/2023/05/230504111839.htm Discovery suggests route to safer pain medications //www.koonmotors.com/releases/2023/05/230503121302.htm Scientists have identified a potential pathway to pain relief that neither triggers addiction nor causes hallucinations. Wed, 03 May 2023 12:13:02 EDT //www.koonmotors.com/releases/2023/05/230503121302.htm How alcohol consumption contributes to chronic pain //www.koonmotors.com/releases/2023/04/230421195030.htm A team showed how both alcohol intake and alcohol withdrawal can lead to increased pain and hypersensitivity. Fri, 21 Apr 2023 19:50:30 EDT //www.koonmotors.com/releases/2023/04/230421195030.htm Study shows most children recover from Lyme disease within six months of treatment //www.koonmotors.com/releases/2023/04/230421112640.htm A majority of parents of children diagnosed with Lyme disease reported that their kids recovered within six months of completing antibiotic treatment, according to a new study. The findings, based on Lyme disease treatment outcome data from 102 children in the United States, also revealed that a notably small percentage of children took longer than six months to recover and experienced a significant impact on their daily functioning. Fri, 21 Apr 2023 11:26:40 EDT //www.koonmotors.com/releases/2023/04/230421112640.htm Students engineer socks for on-the-go neuropathy treatment //www.koonmotors.com/releases/2023/04/230413154132.htm A wearable electrical-stimulation and vibration-therapy system designed by engineering students might be just what the doctor ordered for people experiencing foot pain and balance loss due to diabetic neuropathy. Thu, 13 Apr 2023 15:41:32 EDT //www.koonmotors.com/releases/2023/04/230413154132.htm Fibromyalgia: Pain out of control //www.koonmotors.com/releases/2023/04/230405112151.htm Feeling like we have a degree of control makes us tolerate pain better. In the case of fibromyalgia, however, this simply doesn't work. A study provides clues as to why. Wed, 05 Apr 2023 11:21:51 EDT //www.koonmotors.com/releases/2023/04/230405112151.htm White-tailed deer blood kills bacteria that causes Lyme disease //www.koonmotors.com/releases/2023/03/230330172106.htm As tick season kicks in across the country, scientists have completed research that offers a promising lead in the fight against Lyme disease. Thu, 30 Mar 2023 17:21:06 EDT //www.koonmotors.com/releases/2023/03/230330172106.htm Turn up your favorite song to improve medication efficacy //www.koonmotors.com/releases/2023/03/230322082724.htm While listening to a favorite song is a known mood booster, researchers have discovered that music-listening interventions also can make medicines more effective. Wed, 22 Mar 2023 08:27:24 EDT //www.koonmotors.com/releases/2023/03/230322082724.htm Wearable microscopes advance spinal cord imaging in mice //www.koonmotors.com/releases/2023/03/230321112627.htm Scientists have created wearable microscopes to enable unprecedented insight into the signaling patterns that occur within the spinal cords of mice. This technological advancement will help researchers better understand the neural basis of sensations and movement in healthy and disease contexts, such as chronic pain, itch, amyotrophic lateral sclerosis (ALS), or multiple sclerosis (MS). Tue, 21 Mar 2023 11:26:27 EDT //www.koonmotors.com/releases/2023/03/230321112627.htm Lone star tick bites may be to blame for unexplained digestive problems //www.koonmotors.com/releases/2023/03/230321112559.htm New clinical guidance has been developed to help physicians and patients identify if unexplained digestive symptoms are due to alpha-gal syndrome, a food allergy that is caused by lone star tick bites. Tue, 21 Mar 2023 11:25:59 EDT //www.koonmotors.com/releases/2023/03/230321112559.htm Preterm babies do not habituate to repeated pain //www.koonmotors.com/releases/2023/03/230316114144.htm Preterm infants do not get used to repeated pain in the way that full-term infants, children and adults do habituate to pain, finds a new study. Thu, 16 Mar 2023 11:41:44 EDT //www.koonmotors.com/releases/2023/03/230316114144.htm 新的测试快速识别病人的postoperative pain can be effectively treated by hypnosis //www.koonmotors.com/releases/2023/03/230314155101.htm Hypnosis is an effective treatment for pain for many individuals but determining which patients will benefit most can be challenging. Hypnotizability testing requires special training and in-person evaluation rarely available in the clinical setting. Now, investigators have developed a fast, point-of-care molecular diagnostic test that identifies a subset of individuals who are most likely to benefit from hypnosis interventions for pain treatment. Their study also found that a subset of highly hypnotizable individuals may be more likely to experience high levels of postoperative pain. Tue, 14 Mar 2023 15:51:01 EDT //www.koonmotors.com/releases/2023/03/230314155101.htm Potential new therapeutic target for inflammatory diseases such as lupus and sepsis //www.koonmotors.com/releases/2023/03/230308112118.htm Scientists have made an important breakthrough in understanding what goes wrong in our bodies during the progression of inflammatory diseases and -- in doing so -- unearthed a potential new therapeutic target. The scientists have found that an enzyme called fumarate hydratase is repressed in macrophages, a frontline inflammatory cell type implicated in a range of diseases including lupus, arthritis, sepsis and COVID-19. Wed, 08 Mar 2023 11:21:18 EST //www.koonmotors.com/releases/2023/03/230308112118.htm Spinal cord stimulation doesn't help with back pain, says new review //www.koonmotors.com/releases/2023/03/230308084406.htm People with chronic back pain may turn to spinal cord stimulation to ease their pain, but a Cochrane Review found no sustained benefits to the surgery that outweigh the costs and risks. Wed, 08 Mar 2023 08:44:06 EST //www.koonmotors.com/releases/2023/03/230308084406.htm Researchers develop blood test for anxiety //www.koonmotors.com/releases/2023/03/230307143746.htm Researchers have successfully developed a blood test for anxiety. The test examines biomarkers that can help them objectively determine someone’s risk for developing anxiety, the severity of their current anxiety and which therapies would likely treat their anxiety the best. Tue, 07 Mar 2023 14:37:46 EST //www.koonmotors.com/releases/2023/03/230307143746.htm Fledgling chronic back pain therapy needs more rigorous study //www.koonmotors.com/releases/2023/03/230302093411.htm Cognitive Functional Therapy treats chronic back pain as part of a person's entire pain experience, but more research is needed to assess its effectiveness. Thu, 02 Mar 2023 09:34:11 EST //www.koonmotors.com/releases/2023/03/230302093411.htm How bacteria invade the brain //www.koonmotors.com/releases/2023/03/230301120831.htm New research in mice shows bacteria hijack communication between nerve and immune cells in the meninges -- the protective layers that shield the brain from infection. The experiments detail step by step how bacteria activate pain receptors and initiate a signaling cascade that disables immune cells and culminates in bacterial invasion of the brain. The findings provide much-needed understanding into a critical window during the early stages of bacterial invasion when intervention could halt the spread of infection. The results point to therapeutic pathways for new treatments of bacterial meningitis, an often-fatal disease that can leave survivors with serious neurologic damage. Wed, 01 Mar 2023 12:08:31 EST //www.koonmotors.com/releases/2023/03/230301120831.htm Study identifies four distinct pain trajectories in nursing home residents //www.koonmotors.com/releases/2023/02/230227193315.htm Despite awareness that pain is common in nursing home residents, there has been minimal attention focused on how this pain changes over time. A new study presents compelling evidence of the existence of four distinct pain trajectories in this population. This new understanding of pain over time can help nursing home staff and clinicians better understand, recognize and respond to risk factors associated with persistent pain in individuals living in nursing homes. Ultimately, consideration of pain trajectories may alter courses of care and illness, prevent adverse outcomes and improve quality of life. Mon, 27 Feb 2023 19:33:15 EST //www.koonmotors.com/releases/2023/02/230227193315.htm Being flexible is key to protecting mental wellbeing in people with chronic pain //www.koonmotors.com/releases/2023/02/230227132714.htm Research has found the biggest threat to the mental health of people living with chronic pain isn't necessarily how intense their pain is, but the extent to which it interferes with their daily life. Mon, 27 Feb 2023 13:27:14 EST //www.koonmotors.com/releases/2023/02/230227132714.htm One in three parents may unnecessarily give children fever-reducing medicine //www.koonmotors.com/releases/2023/02/230220121918.htm Some parents may not be properly measuring or responding to elevated temperatures in children, a new national poll suggests. Mon, 20 Feb 2023 12:19:18 EST //www.koonmotors.com/releases/2023/02/230220121918.htm NIH RECOVER research identifies potential long COVID disparities //www.koonmotors.com/releases/2023/02/230216172237.htm Black and Hispanic Americans appear to experience more symptoms and health problems related to long COVID, a lay term that captures an array of symptoms and health problems, than white people, but are not as likely to be diagnosed with the condition, according to new research. Thu, 16 Feb 2023 17:22:37 EST //www.koonmotors.com/releases/2023/02/230216172237.htm Fiber discovery could shape better gut health //www.koonmotors.com/releases/2023/02/230216172214.htm Changing the structure of a dietary fiber commonly found in a range of food products has been found to promote healthy gut bacteria and reduce gas formation, a finding that could help people with intolerances to fiber and irritable bowel conditions. Thu, 16 Feb 2023 17:22:14 EST //www.koonmotors.com/releases/2023/02/230216172214.htm 识别潜在的骨应力损伤after using carbon fiber plate footwear //www.koonmotors.com/releases/2023/02/230213134652.htm Millions of endurance runners use footwear that has an embedded carbon fiber plate (CFP) in the midsole. While the performance benefits that carbon fiber plate footwear offers have been well documented, little has been published about running injuries related to use of this footwear. In a current opinion piece, authors describe five cases in which runners using carbon fiber plate footwear sustained bone stress injuries. Mon, 13 Feb 2023 13:46:52 EST //www.koonmotors.com/releases/2023/02/230213134652.htm Antidepressants used for chronic pain on the rise, but are they effective? //www.koonmotors.com/releases/2023/02/230201195349.htm New research has found some antidepressants may be effective in treating certain chronic pain conditions, but others lack convincing evidence on their effectiveness. Wed, 01 Feb 2023 19:53:49 EST //www.koonmotors.com/releases/2023/02/230201195349.htm Early diagnosis and monitoring of lupus nephritis -- on your smartphone //www.koonmotors.com/releases/2023/02/230201195336.htm A pair of researchers reports the success of their new, at-home method for early diagnosis and monitoring of lupus nephritis. or inflammation of the kidneys, one of the most severe complications for patients with systemic lupus erythematosus, known as lupus. Wed, 01 Feb 2023 19:53:36 EST //www.koonmotors.com/releases/2023/02/230201195336.htm Scientists find that microRNA affects inflammation in lupus disease //www.koonmotors.com/releases/2023/01/230126100201.htm Scientists have discovered the role of microRNA on inflammation in lupus disease. They identified the microRNAs that are downregulated in the disease and how they converge to cause the disease. Thu, 26 Jan 2023 10:02:01 EST //www.koonmotors.com/releases/2023/01/230126100201.htm Gut microbiome and its products promote endometriosis in animal model //www.koonmotors.com/releases/2023/01/230125103959.htm Researchers have discovered that an altered gut microbiome plays a pivotal role in endometriosis disease progression in an animal model. Wed, 25 Jan 2023 10:39:59 EST //www.koonmotors.com/releases/2023/01/230125103959.htm Researchers use AI to triage patients with chest pain //www.koonmotors.com/releases/2023/01/230117110422.htm Artificial intelligence (AI) may help improve care for patients who show up at the hospital with acute chest pain, according to a new study. Tue, 17 Jan 2023 11:04:22 EST //www.koonmotors.com/releases/2023/01/230117110422.htm Study identifies potential new approach for treating lupus //www.koonmotors.com/releases/2023/01/230113145351.htm Targeting iron metabolism in immune system cells may offer a new approach for treating systemic lupus erythematosus (SLE) -- the most common form of the chronic autoimmune disease lupus. A multidisciplinary team of investigators has discovered that blocking an iron uptake receptor reduces disease pathology and promotes the activity of anti-inflammatory regulatory T cells in a mouse model of SLE. Fri, 13 Jan 2023 14:53:51 EST //www.koonmotors.com/releases/2023/01/230113145351.htm Scientists take another step toward building a better pain killer //www.koonmotors.com/releases/2023/01/230112182111.htm New work provides a comprehensive structural framework that should help drug developers rationally design safer drugs to relieve severe pain. Thu, 12 Jan 2023 18:21:11 EST //www.koonmotors.com/releases/2023/01/230112182111.htm Faster knee for better walking //www.koonmotors.com/releases/2023/01/230112090947.htm Scientists delved into the relationship between gait function and knee extension velocity after total knee arthroplasty and compared the effects of various factors on walking. The results reveal that knee extension velocity, measured while seated, on the operated side was the most important determinant of gait function. These findings are expected to contribute to the development of new rehabilitation programs for efficient gait function improvement. Thu, 12 Jan 2023 09:09:47 EST //www.koonmotors.com/releases/2023/01/230112090947.htm Realtime monitoring with a wearable device reveals IBS-related changes //www.koonmotors.com/releases/2023/01/230112090916.htm 一个研究小组记录了自主神经系统stem activity in patients with irritable bowel syndrome (IBS) and healthy subjects using a wearable device and a proprietary smartphone application to record daily life events such as defecation and sleep. As a result, they found that sympathetic nervous system activity was activated in IBS patients from 2 minutes before defecation and continued until 9 minutes after defecation. Further research is expected to improve the quality of life of IBS patients and elucidate the pathophysiology. Thu, 12 Jan 2023 09:09:16 EST //www.koonmotors.com/releases/2023/01/230112090916.htm Common fatty acid contributes to temperature and pain sensitivity in psoriasis plaques //www.koonmotors.com/releases/2023/01/230104085301.htm A common fatty acid found in the Western diet breaks down into compounds that contribute to increased temperature and pain -- but not itch -- sensitivity in psoriatic lesions. Wed, 04 Jan 2023 08:53:01 EST //www.koonmotors.com/releases/2023/01/230104085301.htm Treating gut pain via a Nobel prize-winning receptor //www.koonmotors.com/releases/2022/12/221222203607.htm Targeting a receptor responsible for our sense of touch and temperature, which researchers have now found to be present in our colon, could provide a new avenue for treating chronic pain associated with gastrointestinal disorders such as irritable bowel syndrome. A team examining the colon identified the presence of Piezo2, the subject of the 2021 Nobel Prize in Physiology or Medicine, now known to be responsible for sensing light touch on our skin. Thu, 22 Dec 2022 20:36:07 EST //www.koonmotors.com/releases/2022/12/221222203607.htm New drug offers hope for people with hand osteoarthritis //www.koonmotors.com/releases/2022/12/221221154703.htm A new study has identified that Talarozole, a drug that is known to increase retinoic acid, was able to prevent osteoarthritis (OA) in disease models. Wed, 21 Dec 2022 15:47:03 EST //www.koonmotors.com/releases/2022/12/221221154703.htm Molecular hydrogen as a new strategy for the treatment of chronic pain //www.koonmotors.com/releases/2022/12/221213121557.htm Researchers demonstrate in animal models that water enriched with hydrogen molecules (H2) improves the symptomatology of neuropathic pain and related emotional disturbances. Tue, 13 Dec 2022 12:15:57 EST //www.koonmotors.com/releases/2022/12/221213121557.htm Virtual reality helps reduce patient anxiety and need for sedatives during hand surgery //www.koonmotors.com/releases/2022/12/221207183644.htm Recent research shows patients using virtual reality technology during elective hand surgery required less anesthesia for anxiety during surgery. Wed, 07 Dec 2022 18:36:44 EST //www.koonmotors.com/releases/2022/12/221207183644.htm