//www.koonmotors.com/news/health_medicine/neuropathy/ Latest medical research on neuropathy including methods to ease pain, and new studies on nerve regeneration. en-us Sun, 10 Sep 2023 22:46:38 EDT Sun, 10 Sep 2023 22:46:38 EDT 60 //www.koonmotors.com/images/scidaily-logo-rss.png//www.koonmotors.com/news/health_medicine/neuropathy/ For more science news, visit ScienceDaily. //www.koonmotors.com/releases/2023/07/230731122236.htm Pain experts suggest that scrambler therapy, a noninvasive pain treatment, can yield significant relief for approximately 80% -- 90% of patients with chronic pain, and it may be more effective than another noninvasive therapy: transcutaneous electrical nerve stimulation (TENS). Mon, 31 Jul 2023 12:22:36 EDT //www.koonmotors.com/releases/2023/07/230731122236.htm //www.koonmotors.com/releases/2023/07/230727212040.htm Scientists identified the region where a protein regulates sodium ion channels, inserting the channel's genetic material into a virus to alleviate pain in cell and animal studies. Thu, 27 Jul 2023 21:20:40 EDT //www.koonmotors.com/releases/2023/07/230727212040.htm //www.koonmotors.com/releases/2023/07/230724122651.htm estim神经性疼痛是一种使人衰弱的条件ated to affect as much as 10% of the global population. It results from a damaged or malfunctioning nervous system, stemming from diseases like diabetes, alcoholism, strokes, Parkinson's and other causes like spinal nerve compression, radiation and chemotherapy treatments. Management of neuropathic pain has been particularly challenging as currently prescribed drugs, such as anticonvulsants and antidepressants can have severe adverse effects, are not well-tolerated, take a longer time to work only help a subset of patients. Mon, 24 Jul 2023 12:26:51 EDT //www.koonmotors.com/releases/2023/07/230724122651.htm //www.koonmotors.com/releases/2023/06/230627123030.htm In the midst of a global opioid epidemic, a team of scientists is exploring natural killer (NK) cells as an alternative treatment for neuropathic pain. Researchers gather existing evidence for the impact of NK cells in pain, pointing to their ability to prune the damaged nerve cells that may cause it. They urge the scientific community to explore biological mechanisms underlying NK cell activity to move towards a realistic pain therapy that is both effective and safe. Tue, 27 Jun 2023 12:30:30 EDT //www.koonmotors.com/releases/2023/06/230627123030.htm //www.koonmotors.com/releases/2023/06/230615183107.htm A new study has identified a treatment that could repair myelin in the cortex, undoing some of the damage caused by MS. Thu, 15 Jun 2023 18:31:07 EDT //www.koonmotors.com/releases/2023/06/230615183107.htm //www.koonmotors.com/releases/2023/05/230524181908.htm Recent research has identified a new compound that can stimulate nerve regeneration after injury, as well as protect cardiac tissue from the sort of damage seen in heart attack. Wed, 24 May 2023 18:19:08 EDT //www.koonmotors.com/releases/2023/05/230524181908.htm //www.koonmotors.com/releases/2023/05/230504111839.htm Neuropathic pain -- abnormal hypersensitivity to stimuli -- is associated with impaired quality of life and is often poorly managed. Estimates suggest that 3 percent to 17 percent of adults suffer from neuropathic pain, including a quarter of people with diabetes and a third of people with HIV. Researchers report that a mechanism involving the enzyme Tiam1 in dorsal horn excitatory neurons of the spinal cord both initiates and maintains neuropathic pain. Moreover, they show that targeting spinal Tiam1 with anti-sense oligonucleotides injected into the cerebrospinal fluid effectively alleviated neuropathic pain hypersensitivity. Thu, 04 May 2023 11:18:39 EDT //www.koonmotors.com/releases/2023/05/230504111839.htm //www.koonmotors.com/releases/2023/04/230421195030.htm A team showed how both alcohol intake and alcohol withdrawal can lead to increased pain and hypersensitivity. Fri, 21 Apr 2023 19:50:30 EDT //www.koonmotors.com/releases/2023/04/230421195030.htm //www.koonmotors.com/releases/2023/04/230413154253.htm Investigators recently used a targeted drug to restore muscle strength and correct myotonia in mice with myotonic dystrophy. Thu, 13 Apr 2023 15:42:53 EDT //www.koonmotors.com/releases/2023/04/230413154253.htm //www.koonmotors.com/releases/2023/04/230413154132.htm A wearable electrical-stimulation and vibration-therapy system designed by engineering students might be just what the doctor ordered for people experiencing foot pain and balance loss due to diabetic neuropathy. Thu, 13 Apr 2023 15:41:32 EDT //www.koonmotors.com/releases/2023/04/230413154132.htm //www.koonmotors.com/releases/2023/04/230410111631.htm For more than 100 million Americans who are obese, bariatric surgery may reverse complications related to diabetes, including regenerating damaged nerves, a new study shows. Researchers say the findings suggest that bariatric surgery likely enables the regeneration of the peripheral nerves and, therefore, may be an effective treatment for millions of individuals with obesity who are at risk of developing diabetes and peripheral neuropathy, Mon, 10 Apr 2023 11:16:31 EDT //www.koonmotors.com/releases/2023/04/230410111631.htm //www.koonmotors.com/releases/2023/04/230405112151.htm Feeling like we have a degree of control makes us tolerate pain better. In the case of fibromyalgia, however, this simply doesn't work. A study provides clues as to why. Wed, 05 Apr 2023 11:21:51 EDT //www.koonmotors.com/releases/2023/04/230405112151.htm //www.koonmotors.com/releases/2023/03/230308084406.htm People with chronic back pain may turn to spinal cord stimulation to ease their pain, but a Cochrane Review found no sustained benefits to the surgery that outweigh the costs and risks. Wed, 08 Mar 2023 08:44:06 EST //www.koonmotors.com/releases/2023/03/230308084406.htm //www.koonmotors.com/releases/2023/02/230201195349.htm New research has found some antidepressants may be effective in treating certain chronic pain conditions, but others lack convincing evidence on their effectiveness. Wed, 01 Feb 2023 19:53:49 EST //www.koonmotors.com/releases/2023/02/230201195349.htm //www.koonmotors.com/releases/2023/01/230125121553.htm The study adds to growing evidence that some often-underappreciated, 'non-essential' amino acids play important roles in the nervous system. The findings may provide a new way to identify people at high risk for peripheral neuropathy, as well as a potential treatment option. Wed, 25 Jan 2023 12:15:53 EST //www.koonmotors.com/releases/2023/01/230125121553.htm //www.koonmotors.com/releases/2023/01/230120093105.htm Traumatic injury to the brain, spinal cord and optic nerve in the central nervous system (CNS) are the leading cause of disability and the second leading cause of death worldwide. CNS injuries often result in a catastrophic loss of sensory, motor and visual functions, which is the most challenging problem faced by clinicians and research scientists. Neuroscientists have recently identified and demonstrated a small molecule that can effectively stimulate nerve regeneration and restore visual functions after optic nerve injury, offering great hope for patients with optic nerve injury, such as glaucoma-related vision loss. Fri, 20 Jan 2023 09:31:05 EST //www.koonmotors.com/releases/2023/01/230120093105.htm //www.koonmotors.com/releases/2022/12/221222203607.htm Targeting a receptor responsible for our sense of touch and temperature, which researchers have now found to be present in our colon, could provide a new avenue for treating chronic pain associated with gastrointestinal disorders such as irritable bowel syndrome. A team examining the colon identified the presence of Piezo2, the subject of the 2021 Nobel Prize in Physiology or Medicine, now known to be responsible for sensing light touch on our skin. Thu, 22 Dec 2022 20:36:07 EST //www.koonmotors.com/releases/2022/12/221222203607.htm //www.koonmotors.com/releases/2022/12/221213121557.htm Researchers demonstrate in animal models that water enriched with hydrogen molecules (H2) improves the symptomatology of neuropathic pain and related emotional disturbances. Tue, 13 Dec 2022 12:15:57 EST //www.koonmotors.com/releases/2022/12/221213121557.htm //www.koonmotors.com/releases/2022/11/221130114535.htm Researchers found an existing drug may help decrease side effects of cisplatin, a widely used cancer treatment that was discovered in 1965. Wed, 30 Nov 2022 11:45:35 EST //www.koonmotors.com/releases/2022/11/221130114535.htm //www.koonmotors.com/releases/2022/11/221114132103.htm A new study in mice suggests that a short-term exposure to a high-fat diet may be linked to pain sensations even in the absence of a prior injury or a preexisting condition like obesity or diabetes. The study found that a high-fat diet induced hyperalgesic priming -- a neurological change that represents the transition from acute to chronic pain -- and allodynia, which is pain resulting from stimuli that do not normally provoke pain. Mon, 14 Nov 2022 13:21:03 EST //www.koonmotors.com/releases/2022/11/221114132103.htm //www.koonmotors.com/releases/2022/11/221111103027.htm The autonomic nervous system is known as the control center for involuntary bodily processes such as the beating of our hearts and our breathing. The fact that this part of the nervous system also has the ability to spontaneously restore muscle function following a nerve injury was recently discovered. Their findings may form the basis for improving and developing interventions to treat nerve lesions. Fri, 11 Nov 2022 10:30:27 EST //www.koonmotors.com/releases/2022/11/221111103027.htm //www.koonmotors.com/releases/2022/11/221102141355.htm People who suffer from chronic pain at age 44 are more like to report pain, poor general health, poor mental health outcomes and joblessness in their 50s and 60s, according to a new study. Wed, 02 Nov 2022 14:13:55 EDT //www.koonmotors.com/releases/2022/11/221102141355.htm //www.koonmotors.com/releases/2022/10/221026193528.htm Two new studies support development of a broadly applicable treatment for neurodegenerative diseases that targets a molecule that serves as the central executioner in the death of axons, the wiring of the nervous system. Blocking this molecular executioner prevents axon loss, which has been implicated in many neurodegenerative diseases, from peripheral neuropathies to Parkinson's disease, and glaucoma to amyotrophic lateral sclerosis (ALS). Wed, 26 Oct 2022 19:35:28 EDT //www.koonmotors.com/releases/2022/10/221026193528.htm //www.koonmotors.com/releases/2022/09/220929132540.htm Multiple lipid biomarkers are linked to the development of neuropathy in patients with type 2 diabetes, a new study finds. Participants with high scores for diabetic neuropathy had changes in lipids reflecting impaired energy metabolism. Researchers say the findings bring potential to identify those with the highest risk of developing disease and facilitate more focused management. Thu, 29 Sep 2022 13:25:40 EDT //www.koonmotors.com/releases/2022/09/220929132540.htm //www.koonmotors.com/releases/2022/09/220915123724.htm Scientists show that Schwann cells take over functions of immune cells in nerve healing. Similar mechanisms could prevent nerve tumors from growing. Thu, 15 Sep 2022 12:37:24 EDT //www.koonmotors.com/releases/2022/09/220915123724.htm //www.koonmotors.com/releases/2022/09/220908112442.htm Most children with a condition that causes a temporary weakness or paralysis of the muscles in the face recover without medication within six months, according to a new study. Thu, 08 Sep 2022 11:24:42 EDT //www.koonmotors.com/releases/2022/09/220908112442.htm //www.koonmotors.com/releases/2022/09/220906114244.htm Researchers test the efficacy of a soft, bioresorbable, implantable device to block pain signals from sciatic nerves of rat models. Tue, 06 Sep 2022 11:42:44 EDT //www.koonmotors.com/releases/2022/09/220906114244.htm //www.koonmotors.com/releases/2022/08/220831152736.htm A new study points to possible new treatments for chronic pain with a surprising link to lung cancer. Findings of the research, conducted in laboratory mouse models, open up multiple therapeutic opportunities that could allow the world to improve chronic pain management and eclipse the opioid epidemic. Wed, 31 Aug 2022 15:27:36 EDT //www.koonmotors.com/releases/2022/08/220831152736.htm //www.koonmotors.com/releases/2022/08/220811083335.htm 一个团队发现,电刺激的e body combined with sound activates the brain's somatosensory cortex, increasing the potential for using the technique to treat chronic pain and other sensory disorders. Thu, 11 Aug 2022 08:33:35 EDT //www.koonmotors.com/releases/2022/08/220811083335.htm //www.koonmotors.com/releases/2022/08/220810161145.htm The number of privately insured adults in the United States prescribed opioid medications for cancer pain and for chronic non-cancer pain declined between 2012 and 2019, according to a new study. Wed, 10 Aug 2022 16:11:45 EDT //www.koonmotors.com/releases/2022/08/220810161145.htm //www.koonmotors.com/releases/2022/08/220810105158.htm A biomedical engineer has developed a way to measure mental activity using electrodermal activity (EDA) -- an electrical phenomenon of the skin that is influenced by brain activity related to emotional status. They describe a novel inference engine that can monitor brain activity through the skin in real time with high scalability and accuracy. Wed, 10 Aug 2022 10:51:58 EDT //www.koonmotors.com/releases/2022/08/220810105158.htm //www.koonmotors.com/releases/2022/08/220808093002.htm 二十碳五烯酸(EPA)——一个ac的ω- 3脂肪酸id -- is known to reduce both neuropathic and inflammatory pain, but the underlying molecular targets for EPA remain unknown. Researchers have now identified 'vesicular nucleotide transporter' as a novel molecular target of EPA, and elucidated mechanisms underlying the analgesic effect of EPA. Their findings suggest that nutrient-based EPA may serve as an effective pain-relief alternative with minimal side-effects compared to opioids. Mon, 08 Aug 2022 09:30:02 EDT //www.koonmotors.com/releases/2022/08/220808093002.htm //www.koonmotors.com/releases/2022/07/220712102650.htm Scientists have shown that a brain-penetrating candidate drug currently in development as a cancer therapy can foster regeneration of damaged nerves after spinal trauma. The announcement comes weeks after the same research team showed a different investigational drug can reduce damage after spinal cord injury, by blocking the inflammatory response. Tue, 12 Jul 2022 10:26:50 EDT //www.koonmotors.com/releases/2022/07/220712102650.htm //www.koonmotors.com/releases/2022/07/220707100950.htm People with two pediatric-onset neurodevelopmental disorders are prescribed opioids at a rate up to five times higher than those who do not have those conditions, a new study finds. Researchers say the findings raise concerns over addiction, overdose and mental health issues. Thu, 07 Jul 2022 10:09:50 EDT //www.koonmotors.com/releases/2022/07/220707100950.htm //www.koonmotors.com/releases/2022/06/220630142129.htm Researchers have developed a small, soft, flexible implant that relieves pain on demand and without the use of drugs. The first-of-its-kind device could provide a much-needed alternative to opioids and other highly addictive medications. It works by softly wrapping around nerves to deliver precise, targeted cooling, which numbs nerves and blocks pain signals to the brain. After the device is no longer needed, it naturally absorbs into the body -- bypassing the need for surgical extraction. Thu, 30 Jun 2022 14:21:29 EDT //www.koonmotors.com/releases/2022/06/220630142129.htm //www.koonmotors.com/releases/2022/06/220628144607.htm Now a new review study has found acetaminophen is safe in older adults, but non-steroidal anti-inflammatories (ibuprofen) may be more effective for spine-related pain. Non-steroidal anti-inflammatories should be used short-term in lower dose courses with gastrointestinal precaution while corticosteroids show the least evidence for treating nonspecific back pain. Tue, 28 Jun 2022 14:46:07 EDT //www.koonmotors.com/releases/2022/06/220628144607.htm //www.koonmotors.com/releases/2022/06/220628113334.htm Scientists reveal their development of a new type of prosthetic using microfluidics-enabled soft robotics that promises to greatly reduce skin ulcerations and pain in patients who have had an amputation between the ankle and knee. They started with a recent device that uses pneumatic actuators and miniaturized the actuators by designing a microfluidic chip with 10 integrated pneumatic valves to control each actuator. The control box is small and light enough to be worn as part of the prosthesis. Tue, 28 Jun 2022 11:33:34 EDT //www.koonmotors.com/releases/2022/06/220628113334.htm //www.koonmotors.com/releases/2022/06/220621184506.htm Amyotrophic lateral sclerosis (ALS) is a progressive disease of the nervous system. It affects nerve cells in the brain and spinal cord called motor neurons. Motor neurons control muscle movement and ALS causes them to deteriorate and eventually die. The motor neurons lose the ability to send messages to the muscles in the body, affecting voluntary muscle movements. There have been recent advances in treating ALS, but current treatments can only slow disease progression. That is why it is important to diagnose ALS as early as possible. Tue, 21 Jun 2022 18:45:06 EDT //www.koonmotors.com/releases/2022/06/220621184506.htm //www.koonmotors.com/releases/2022/06/220613112123.htm 研究人员揭示潜在的新方法治疗chronic pain using anti-cancer drugs rather than opioid-based pain medication. Researchers identified the existence of a molecule in the nervous system that enhances sensitivity to pain. This molecule had previously been thought to play a role in cancer growth but had never been reported in the nervous system. By targeting this molecule it may now be possible to use already existing anti-cancer drugs to block pain. Mon, 13 Jun 2022 11:21:23 EDT //www.koonmotors.com/releases/2022/06/220613112123.htm //www.koonmotors.com/releases/2022/06/220606181234.htm Evidence behind the effectiveness of cannabis-related products to treat chronic pain is surprisingly thin, according to a new systematic evidence review. Voters in a number of states have legalized medical and recreational marijuana; however, the researchers found many of the products now available at U.S. dispensaries have not been well studied. Mon, 06 Jun 2022 18:12:34 EDT //www.koonmotors.com/releases/2022/06/220606181234.htm //www.koonmotors.com/releases/2022/06/220602140801.htm A large genetic study has found that a person's height may affect their risk for several common health conditions in adulthood. Significant findings include a link between height and lower risk of coronary heart disease, and a link between height and higher risk for peripheral neuropathy and circulatory disorders. Thu, 02 Jun 2022 14:08:01 EDT //www.koonmotors.com/releases/2022/06/220602140801.htm //www.koonmotors.com/releases/2022/05/220520073143.htm Scientists have shown an existing drug may reduce damage after spinal cord injury, by blocking the inflammatory response in the spinal cord. Fri, 20 May 2022 07:31:43 EDT //www.koonmotors.com/releases/2022/05/220520073143.htm //www.koonmotors.com/releases/2022/05/220509150753.htm Researchers report that a gene therapy that inhibits targeted nerve cell signaling effectively reduced neuropathic pain with no detectable side effects in mice with spinal cord or peripheral nerve injuries. Mon, 09 May 2022 15:07:53 EDT //www.koonmotors.com/releases/2022/05/220509150753.htm //www.koonmotors.com/releases/2022/04/220427140624.htm Researchers have shown how chronic pain leads to maladaptive anxiety in mice, with implications for treatment of chronic pain-related psychiatric disorders in humans. Wed, 27 Apr 2022 14:06:24 EDT //www.koonmotors.com/releases/2022/04/220427140624.htm //www.koonmotors.com/releases/2022/04/220427115821.htm Using genetic approaches, researchers have demonstrated how a certain protein is involved in skeletal muscle growth. The findings open new avenues to develop drug targets for neuromuscular diseases and other pathological conditions. Wed, 27 Apr 2022 11:58:21 EDT //www.koonmotors.com/releases/2022/04/220427115821.htm //www.koonmotors.com/releases/2022/03/220325122658.htm Researchers have found that many people who tested positive for the coronavirus in the early months of the pandemic also experienced peripheral neuropathy -- pain, tingling and numbness in the hands and feet -- during and following their bouts with COVID-19. Fri, 25 Mar 2022 12:26:58 EDT //www.koonmotors.com/releases/2022/03/220325122658.htm //www.koonmotors.com/releases/2022/03/220324184652.htm 一项新的研究使用神经肌肉电stimulation (NMES) in zebrafish found that certain activities may help strengthen muscles affected by Duchenne muscular dystrophy, a severe type of muscular dystrophy that affects young boys. The researchers designed four NMES regimens for zebrafish with a mutation that closely modeled the disease. They then put the fish into an underwater 3D printed 'gym' made up of tunnels and electrodes, and analyzed their skeletal muscles to see how they had changed. Thu, 24 Mar 2022 18:46:52 EDT //www.koonmotors.com/releases/2022/03/220324184652.htm //www.koonmotors.com/releases/2022/03/220318170516.htm An investigation into how human sensory neurons differ from animal neurons has provided researchers with important clues in the pursuit of more effective treatments for chronic pain. Researchers are analyzing the origins of how pain is generated by nociceptors in human dorsal root ganglia (DRG) neurons, charting the full transcriptome of messenger RNA strands produced in these cells. Fri, 18 Mar 2022 17:05:16 EDT //www.koonmotors.com/releases/2022/03/220318170516.htm //www.koonmotors.com/releases/2022/03/220316145731.htm Researchers have identified a molecule essential for regulating the repair of injured nerves, which could help people recover from nerve damage. Wed, 16 Mar 2022 14:57:31 EDT //www.koonmotors.com/releases/2022/03/220316145731.htm //www.koonmotors.com/releases/2022/03/220311132730.htm Researchers have found that repulsive guidance molecule-a (RGMa) induces macrophages to recruit neutrophils to nerve lesions in neuromyelitis optica, where they kill off astrocytes, causing pain and paralysis. Treating rats with an anti-RGMa antibody interrupted this signaling process, resulting in decreased neutrophil recruitment, increased astrocyte survival, and improvement in disease-associated symptoms. Fri, 11 Mar 2022 13:27:30 EST //www.koonmotors.com/releases/2022/03/220311132730.htm //www.koonmotors.com/releases/2022/03/220301162000.htm Most post-COVID nerve damage appears to be caused by infection-triggered immune dysfunction -- not by lingering infection -- suggesting patients might benefit from currently available immunotherapies. Tue, 01 Mar 2022 16:20:00 EST //www.koonmotors.com/releases/2022/03/220301162000.htm //www.koonmotors.com/releases/2022/02/220223085804.htm Scientists depict the early development of pain-sensing and movement-sensing neurons in the face and throat. The findings reveal a previously unexplored feature of brain and cranial nerve development underlying eating, swallowing, and speech. Wed, 23 Feb 2022 08:58:04 EST //www.koonmotors.com/releases/2022/02/220223085804.htm //www.koonmotors.com/releases/2022/02/220217141254.htm Researchers found a way to inhibit the mitochondrial fission in nerve cell axons, which can promote normal growth and potentially stop further damage in neurodegenerative disorders like hereditary spastic paraplegia and Parkinson's disease. Thu, 17 Feb 2022 14:12:54 EST //www.koonmotors.com/releases/2022/02/220217141254.htm //www.koonmotors.com/releases/2022/02/220217141220.htm Developing therapies for genetic forms of blindness is extremely challenging, in part because they vary so widely, but scientists have now highlighted a target with great promise for treating a range of these conditions. The scientists have highlighted that a specific gene (SARM1) is a key driver in the damage that ultimately leads to impaired vision (and sometimes blindness), and -- in a disease model -- showed that deleting this gene protects vision after a chemical kick-starts the chain of dysfunction that mimics a host of ocular conditions. Thu, 17 Feb 2022 14:12:20 EST //www.koonmotors.com/releases/2022/02/220217141220.htm //www.koonmotors.com/releases/2022/01/220127104259.htm Researchers have discovered that a particular molecular signaling pathway plays an important role in producing osteoarthritis (OA) pain. Using a mouse model of painful osteoarthritis, they show that blocking this signaling pathway eliminates pain and results in a return to normal limb use. This work is the first to find an association between this pathway and OA pain, and could lead to the development of new, effective pain treatments for human OA sufferers. Thu, 27 Jan 2022 10:42:59 EST //www.koonmotors.com/releases/2022/01/220127104259.htm //www.koonmotors.com/releases/2021/12/211220144957.htm A researcher has identified the proteins necessary for efficient regeneration of skeletal muscles after acute injury and in Duchenne Muscular Dystrophy (DMD) clearing the way for drug development for skeletal muscle diseases. Mon, 20 Dec 2021 14:49:57 EST //www.koonmotors.com/releases/2021/12/211220144957.htm //www.koonmotors.com/releases/2021/11/211122172714.htm Opioid medications remain a go-to treatment for severe pain, whether it's from surgery, a sudden injury, or nerve damage. But as opioid addiction and overdose deaths reach new highs in the United States, the need for safer ways to treat acute pain has grown more urgent. A new collection of compounds shows promise. Mon, 22 Nov 2021 17:27:14 EST //www.koonmotors.com/releases/2021/11/211122172714.htm //www.koonmotors.com/releases/2021/11/211104162636.htm Blocking a molecule that draws sensory nerves into musculoskeletal injuries prevents heterotopic ossification (HO), a process in which bone abnormally grows in soft tissue during healing, researchers reported. The findings suggest that drugs currently being tested in clinical trials to inhibit this molecule for pain relief could also protect against this challenging condition. Thu, 04 Nov 2021 16:26:36 EDT //www.koonmotors.com/releases/2021/11/211104162636.htm //www.koonmotors.com/releases/2021/10/211027172626.htm The number of people experiencing numbness, tingling and pain in their feet with no known cause has been increasing over the last two decades, according at a new study. Called small fiber neuropathy, the condition has different symptoms than large fiber neuropathy, which can cause weakness and balance issues. But in many cases people have both types of neuropathy. Wed, 27 Oct 2021 17:26:26 EDT //www.koonmotors.com/releases/2021/10/211027172626.htm //www.koonmotors.com/releases/2021/10/211022171503.htm A new study reveals the specific molecular mechanism that controls the transition from acute to chronic pain, and identifies this mechanism as a critical target for disease-modifying medicines. Fri, 22 Oct 2021 17:15:03 EDT //www.koonmotors.com/releases/2021/10/211022171503.htm