//www.koonmotors.com/news/health_medicine/lung_cancer/ Information about lung cancer symptoms and treatments. Explore the latest medical research on cancers including experimental treatments. en-us Fri, 08 Sep 2023 22:46:03 EDT Fri, 08 Sep 2023 22:46:03 EDT 60 //www.koonmotors.com/images/scidaily-logo-rss.png//www.koonmotors.com/news/health_medicine/lung_cancer/ For more science news, visit ScienceDaily. //www.koonmotors.com/releases/2023/09/230904104625.htm Scientists have discovered two new genes that cause head and neck cancer patients to be resistant to chemotherapy, and that silencing either gene can make cancer cells previously unresponsive to chemotherapy subsequently respond to it. Mon, 04 Sep 2023 10:46:25 EDT //www.koonmotors.com/releases/2023/09/230904104625.htm //www.koonmotors.com/releases/2023/08/230831142816.htm Vitamin C and other antioxidants stimulate the formation of new blood vessels in lung cancer tumors, a new study shows. The discovery corroborates the idea that dietary supplements containing antioxidants can accelerate tumor growth and metastasis. Thu, 31 Aug 2023 14:28:16 EDT //www.koonmotors.com/releases/2023/08/230831142816.htm //www.koonmotors.com/releases/2023/08/230830131855.htm Fresh discoveries about a type of immune cells could give lung cancer patients a more accurate prognosis and better identify who will benefit from immunotherapies. Researchers found that the location in and around tumours of cytotoxic T cells, which play a key role in fighting cancer, may help predict patient survival and indicate whether or not treatments will work. Wed, 30 Aug 2023 13:18:55 EDT //www.koonmotors.com/releases/2023/08/230830131855.htm //www.koonmotors.com/releases/2023/08/230814122018.htm Patients with localized prostate cancer have a good chance of survival, but mortality rates among those with advanced, metastatic forms of the condition remain high. Until now, the precise mechanism behind the spread of the tumor has not been fully explained. But an international research team has succeeded in decoding the underlying cellular signal pathway and has carried out research using a common diabetes medication that could provide a new treatment option. Mon, 14 Aug 2023 12:20:18 EDT //www.koonmotors.com/releases/2023/08/230814122018.htm //www.koonmotors.com/releases/2023/08/230809130623.htm New findings may lead to relapse-free treatment for a sizeable subgroup of lung cancer patients. In a study in mice, scientists have identified a biomarker that may help physicians select lung cancer patients who can be treated with a single antibody-based drug that is likely to bring about full remission, without cancer relapse. Wed, 09 Aug 2023 13:06:23 EDT //www.koonmotors.com/releases/2023/08/230809130623.htm //www.koonmotors.com/releases/2023/07/230712124752.htm Cancer therapies that target specific genetic abnormalities in tumors have revolutionized treatment possibilities over the past two decades. While quality of life and survival are improved with targeted therapies, relapse is common due to the evolution of new tumor cells that are resistant to the targeted therapy. A new study reveals how lung tumors may develop drug resistance over time, pointing to a protein, called APOBEC3A, that could be a promising target. Results may help researchers develop new solutions for tumor resistance to targeted cancer therapies. Wed, 12 Jul 2023 12:47:52 EDT //www.koonmotors.com/releases/2023/07/230712124752.htm //www.koonmotors.com/releases/2023/07/230712124705.htm 前列腺癌是死亡的主要原因American men, and it's resistant to one of the most powerful chemotherapy medications -- cisplatin. Now, researchers have developed the first therapy of its kind that disrupts prostate cancer cells' metabolism and releases cisplatin into the weakened cells, causing them to die. In mouse models, an orally administered version shrunk tumors substantially. Wed, 12 Jul 2023 12:47:05 EDT //www.koonmotors.com/releases/2023/07/230712124705.htm //www.koonmotors.com/releases/2023/06/230622120900.htm Small-cell lung cancer is a particularly aggressive type of tumor with a consistently high mortality rate. In recent years, the research of scientists has significantly contributed to a better understanding and new therapeutic approaches in this malignant disease. Thu, 22 Jun 2023 12:09:00 EDT //www.koonmotors.com/releases/2023/06/230622120900.htm //www.koonmotors.com/releases/2023/03/230328145216.htm Researchers develop a 3D cell culture system to test how inhibiting fibroblast activities can help treat lung cancer. To simulate the tumor microenvironment and mimic real tissues, the team co-cultured lung cancer cells and fibroblasts in a 3D matrix. The researchers then tested the anti-cancer drug cisplatin with and without two anti-fibrotic drugs, nintedanib and pirfenidone. They found that combining the anti-fibrotic drug nintedanib with the anti-cancer drug cisplatin increased the efficacy of the latter. Tue, 28 Mar 2023 14:52:16 EDT //www.koonmotors.com/releases/2023/03/230328145216.htm //www.koonmotors.com/releases/2023/03/230317184940.htm A new study has revealed FDA-approved trametinib and entinostat (which is currently in clinical trials) can be given in tandem to produce fewer and smaller tumors in mice with LKB1-mutated non-small cell lung cancer. Fri, 17 Mar 2023 18:49:40 EDT //www.koonmotors.com/releases/2023/03/230317184940.htm //www.koonmotors.com/releases/2023/03/230315132413.htm A new study represents a first step towards generating highly detailed 3-dimensional maps of lung tumors using genetically engineered mouse models. Wed, 15 Mar 2023 13:24:13 EDT //www.koonmotors.com/releases/2023/03/230315132413.htm //www.koonmotors.com/releases/2023/03/230313120939.htm Scientists have discovered why breast cancer cells that have spread to the lungs may 'wake up' following years of sleep -- forming incurable secondary tumors. Their research reveals the mechanism that triggers this breast cancer 'time bomb' -- and suggests a strategy to defuse it. Mon, 13 Mar 2023 12:09:39 EDT //www.koonmotors.com/releases/2023/03/230313120939.htm //www.koonmotors.com/releases/2023/02/230213120643.htm Researchers show how stimulating dendritic cells through certain pathways produces strong T cell activity against tumors and works in conjunction with immune checkpoint inhibitors to produce even stronger responses. The article also shares promising early results from a phase 1 clinical study of an oncolytic virus (MEM-288) that activates these pathways in patients with non-small cell lung cancer. Mon, 13 Feb 2023 12:06:43 EST //www.koonmotors.com/releases/2023/02/230213120643.htm //www.koonmotors.com/releases/2023/01/230131183139.htm New data from a clinical trial shows improved rates of survival and reduced risk of recurrence in patients taking osimertinib, a targeted therapy for non-small cell lung cancer (NSCLC). Tue, 31 Jan 2023 18:31:39 EST //www.koonmotors.com/releases/2023/01/230131183139.htm //www.koonmotors.com/releases/2023/01/230109112729.htm A new study found that deleting a gene called KMT2D caused normal (basal) lung cells grown in complex cultures called organoids to transform into lung squamous carcinoma (LUSC) cells. Mon, 09 Jan 2023 11:27:29 EST //www.koonmotors.com/releases/2023/01/230109112729.htm //www.koonmotors.com/releases/2022/12/221229115715.htm A research team has shown that Sarunashi juice and its constituting component isoquercetin help prevent and reduce lung cancer in laboratory mice. Thu, 29 Dec 2022 11:57:15 EST //www.koonmotors.com/releases/2022/12/221229115715.htm //www.koonmotors.com/releases/2022/12/221226094519.htm Researchers report that they have developed a new experimental pipeline to combine bacterial therapy with current cancer drugs. Their study, which explores resistance to bacterial therapy at the molecular level, has achieved better treatment efficacy without additional toxicity in laboratory models. Mon, 26 Dec 2022 09:45:19 EST //www.koonmotors.com/releases/2022/12/221226094519.htm //www.koonmotors.com/releases/2022/12/221201203926.htm About 80% of people with cancer suffer from significant muscle wasting, or loss of muscle tissue, and 30% of these patients die from this condition. New research in mice finds that the severity of muscle wasting is related to the type, size and location of the tumor. Thu, 01 Dec 2022 20:39:26 EST //www.koonmotors.com/releases/2022/12/221201203926.htm //www.koonmotors.com/releases/2022/11/221129143827.htm While it may seem common knowledge that smoking is bad for your lungs, if and how ultrafine particles present in cigarette smoke impact the development and progression of lung cancer remains unclear. Working with animal models, researchers sought to find how airborne ultrafine particles in smoke can change a host's defense against lung cancer. Tue, 29 Nov 2022 14:38:27 EST //www.koonmotors.com/releases/2022/11/221129143827.htm //www.koonmotors.com/releases/2022/11/221115113940.htm Airway inflammation and emphysema are more common in marijuana smokers than cigarette smokers, according to a new study. Researchers said the difference may be due to the way that marijuana is smoked and the fact that marijuana smoke enters the lungs unfiltered. Tue, 15 Nov 2022 11:39:40 EST //www.koonmotors.com/releases/2022/11/221115113940.htm //www.koonmotors.com/releases/2022/11/221108120419.htm Scientists investigating the mechanics of the early stages of lung cancer have identified a new potential treatment, which could also aid early detection of the disease. Levels of a key protein -- called TLR2 -- in tumors was found to predict a patient's survival after being diagnosed with lung cancer, a study shows. A drug compound that activates TLR2 was tested in mice and was found to reduce tumor growth in the early stages of the disease. Tue, 08 Nov 2022 12:04:19 EST //www.koonmotors.com/releases/2022/11/221108120419.htm //www.koonmotors.com/releases/2022/10/221025090509.htm A new study has revealed significant racial disparities in how quickly minorities with the most common form of lung cancer receive potentially lifesaving radiation therapy compared with their white counterparts. Tue, 25 Oct 2022 09:05:09 EDT //www.koonmotors.com/releases/2022/10/221025090509.htm //www.koonmotors.com/releases/2022/10/221006154703.htm This year, about 200,000 people will be diagnosed with non-small-cell lung cancer, the second leading cause of death after cardiovascular disease. Researchers are working to improve the odds for these patients in two recently published studies that combine novel multiplex cellular imaging methods with artificial intelligence to learn why and how patients respond differently to disease and treatments. Thu, 06 Oct 2022 15:47:03 EDT //www.koonmotors.com/releases/2022/10/221006154703.htm //www.koonmotors.com/releases/2022/09/220928094753.htm 尽管有重大进展,死亡率的大脑tumors remains high with five-year survival rates of 36%. More accurate diagnoses might improve the situation, but tissue biopsies are invasive and can miss important information about a tumor's make-up. Imaging-based methods, meanwhile, do not offer sufficient sensitivity and resolution. Now, researchers have developed a biosensor that could help physicians precisely diagnose brain cancer from a minute blood sample. Wed, 28 Sep 2022 09:47:53 EDT //www.koonmotors.com/releases/2022/09/220928094753.htm //www.koonmotors.com/releases/2022/09/220921141505.htm The majority of the socioeconomic disparity, or deprivation gap, in cancer incidence could have been prevented in England between 2013 and 2017 if nobody had smoked, according to a new study. Wed, 21 Sep 2022 14:15:05 EDT //www.koonmotors.com/releases/2022/09/220921141505.htm //www.koonmotors.com/releases/2022/09/220916112451.htm In Germany, about ten per cent of all children are born before the 37th week of pregnancy and are thus considered premature. Many of these premature babies require help with breathing due to their underdeveloped lungs. However, clinical practice shows that mechanical ventilation can cause irreversible damage to the lungs, although the exact causes are not yet known. In an interdisciplinary study, physicists and physicians have now shown that increased pressure on the lung tissue, as caused by mechanical ventilation, poses the risk of overstretching the tissue, even with small amounts of air, and disrupting cell function during gas exchange. Fri, 16 Sep 2022 11:24:51 EDT //www.koonmotors.com/releases/2022/09/220916112451.htm //www.koonmotors.com/releases/2022/09/220913110445.htm Researchers used extensive single-cell analysis to create a spatial map of tumor-infiltrating B cells and plasma cells in early-stage lung cancers, revealing new roles for these immune cells in cancer development and immunotherapy responses. Tue, 13 Sep 2022 11:04:45 EDT //www.koonmotors.com/releases/2022/09/220913110445.htm //www.koonmotors.com/releases/2022/09/220913110412.htm 一个新的机制been identified through which very small pollutant particles in the air may trigger lung cancer in people who have never smoked, paving the way to new prevention approaches and development of therapies. The particles, which are typically found in vehicle exhaust and smoke from fossil fuels, are associated with non-small cell lung cancer (NSCLC) risk, accounting for over 250,000 lung cancer deaths globally per year. Tue, 13 Sep 2022 11:04:12 EDT //www.koonmotors.com/releases/2022/09/220913110412.htm //www.koonmotors.com/releases/2022/09/220901151622.htm About 30,000 cases of lung cancer occur in Spain each year. Mutations in KRAS oncogenes account for 10-15% of these cases, a subgroup against which there are still no effective therapies. Researchers have succeeded in determining the structure of the RAF1 protein, a therapeutic target against cancers associated with KRAS oncogenes. Thu, 01 Sep 2022 15:16:22 EDT //www.koonmotors.com/releases/2022/09/220901151622.htm //www.koonmotors.com/releases/2022/08/220831210036.htm An experimental combination of two drugs halts the progression of small cell lung cancer, the deadliest form of lung cancer, according to a study in mice. Wed, 31 Aug 2022 21:00:36 EDT //www.koonmotors.com/releases/2022/08/220831210036.htm //www.koonmotors.com/releases/2022/08/220809101735.htm More females than males who have never smoked have lung cancer and increasing evidence indicates that air pollution may be a major risk factor for these patients. Tue, 09 Aug 2022 10:17:35 EDT //www.koonmotors.com/releases/2022/08/220809101735.htm //www.koonmotors.com/releases/2022/07/220720150632.htm Scientists have found that using immunotherapy alongside a drug that blocks a common gene mutation in lung cancer could be a promising new combination therapy for certain types of lung tumors. Their work could help select patients for clinical trials to confirm whether this combination therapy is effective in people. Wed, 20 Jul 2022 15:06:32 EDT //www.koonmotors.com/releases/2022/07/220720150632.htm //www.koonmotors.com/releases/2022/07/220718122243.htm Researchers have found a new way to track metastatic cancer cells in the body, which in the future could help identify cancer earlier and give patients more treatment options. Mon, 18 Jul 2022 12:22:43 EDT //www.koonmotors.com/releases/2022/07/220718122243.htm //www.koonmotors.com/releases/2022/07/220714091115.htm Treatment for lung cancer has improved in recent years, and a new study has found how to make it even more effective for all patients. Thu, 14 Jul 2022 09:11:15 EDT //www.koonmotors.com/releases/2022/07/220714091115.htm //www.koonmotors.com/releases/2022/07/220712102711.htm Offering intensive, weekly telephone-based cessation counseling along with nicotine replacement for people who smoke and who were undergoing screening for lung cancer resulted in over a two-fold greater cigarette quit rate compared to people who received minimal counseling and nicotine replacement, according to results of a national, randomized trial. Tue, 12 Jul 2022 10:27:11 EDT //www.koonmotors.com/releases/2022/07/220712102711.htm //www.koonmotors.com/releases/2022/06/220614153741.htm A study shows a strong relationship between prolonged exposure to low levels of radon and lung cancer, indicating a need for enhanced protection measures. Radon gas in the air decays into tiny radioactive particles which can damage lung cells and lead to cancer. Tue, 14 Jun 2022 15:37:41 EDT //www.koonmotors.com/releases/2022/06/220614153741.htm //www.koonmotors.com/releases/2022/06/220603155423.htm Nearly 43% of patients with non-small cell lung cancer (NSCLC) whose lung cancers harbored a specific KRAS mutation responded to the experimental drug adagrasib, and the targeted agent also showed activity against lesions in the brain that metastasized from the lung tumors, according to results of a new study. Fri, 03 Jun 2022 15:54:23 EDT //www.koonmotors.com/releases/2022/06/220603155423.htm //www.koonmotors.com/releases/2022/06/220602132312.htm Scientists develop a blood test that could help with early detection of non-small cell lung cancer, as well as potential drug resistance. Thu, 02 Jun 2022 13:23:12 EDT //www.koonmotors.com/releases/2022/06/220602132312.htm //www.koonmotors.com/releases/2022/06/220602095120.htm 研究人员首次验证a simple blood test called a liquid biopsy could be a better predictor of whether cancer immunotherapy will be successful for a patient with lung cancer than an invasive tumor biopsy procedure. Thu, 02 Jun 2022 09:51:20 EDT //www.koonmotors.com/releases/2022/06/220602095120.htm //www.koonmotors.com/releases/2022/05/220517094834.htm Small cell lung cancer (SCLC) is a malignant disease associated with a particularly high mortality rate. According to a new multicenter study, SCLC can be divided into several subgroups in terms of clinical behavior. These subtypes respond differently to chemotherapeutics and targeted drugs. This opens up possibilities for personalized treatment for this type of cancer as well. Tue, 17 May 2022 09:48:34 EDT //www.koonmotors.com/releases/2022/05/220517094834.htm //www.koonmotors.com/releases/2022/05/220504110424.htm Researchers share the identification of a new potential target for CAR T cells called OR2H1 that they have demonstrated inhibits growth in lung and ovarian tumors. Wed, 04 May 2022 11:04:24 EDT //www.koonmotors.com/releases/2022/05/220504110424.htm //www.koonmotors.com/releases/2022/05/220503102847.htm CT-detected emphysema is linked to a higher risk of lung cancer, a risk that increases with emphysema severity, according to a new study. Tue, 03 May 2022 10:28:47 EDT //www.koonmotors.com/releases/2022/05/220503102847.htm //www.koonmotors.com/releases/2022/04/220425121056.htm Metastatic breast cancer cells abuse macrophages, a type of immune cell, to promote the settlement of cancer metastases in the lungs. The reprogrammed macrophages stimulate blood vessel cells to secrete a cocktail of metastasis-promoting proteins that are part of the so-called metastatic niche. Mon, 25 Apr 2022 12:10:56 EDT //www.koonmotors.com/releases/2022/04/220425121056.htm //www.koonmotors.com/releases/2022/04/220420133530.htm Cancer researchers say they have successfully suppressed the growth of some solid tumors in research models by manipulating immune cells known as a macrophages. Wed, 20 Apr 2022 13:35:30 EDT //www.koonmotors.com/releases/2022/04/220420133530.htm //www.koonmotors.com/releases/2022/04/220419112520.htm Scientists have identified a mechanism that explains how fine air pollution particles might cause lung cancer, according to a new study. Tue, 19 Apr 2022 11:25:20 EDT //www.koonmotors.com/releases/2022/04/220419112520.htm //www.koonmotors.com/releases/2022/04/220411113733.htm Cigarette smoking is overwhelmingly the main cause of lung cancer, yet only a minority of smokers develop the disease. A study suggests that some smokers may have robust mechanisms that protect them from lung cancer by limiting mutations. The findings could help identify those smokers who face an increased risk for the disease and therefore warrant especially close monitoring. Mon, 11 Apr 2022 11:37:33 EDT //www.koonmotors.com/releases/2022/04/220411113733.htm //www.koonmotors.com/releases/2022/04/220407141908.htm Bacteria promote cancer metastasis by bolstering the strength of host cells against mechanical stress in the bloodstream, promoting cell survival during tumor progression, researchers report. Thu, 07 Apr 2022 14:19:08 EDT //www.koonmotors.com/releases/2022/04/220407141908.htm //www.koonmotors.com/releases/2022/03/220330141427.htm Searching for ways to extend the survival benefit of targeted therapies, a team led by researchers has identified a potential new tactic to disrupt the repair mechanism that cancer cells use after treatment, blunting their ability to regenerate. The approach could present a new treatment strategy. 结婚,2022年3月30日14:14:27美国东部时间 //www.koonmotors.com/releases/2022/03/220330141427.htm //www.koonmotors.com/releases/2022/03/220324154140.htm Researchers have developed a novel method to identify aggressive early-stage lung cancers and target drugs known as aurora kinase inhibitors to tumors that are especially likely to respond to them. The findings could lead to great advances in treatment for lung adenocarcinoma, the most common type of lung cancer. Thu, 24 Mar 2022 15:41:40 EDT //www.koonmotors.com/releases/2022/03/220324154140.htm //www.koonmotors.com/releases/2022/03/220324104430.htm Intense light activates proteins shown to protect against lung damage in mice, a discovery that could have major therapeutic implications for treating diseases like acute lung injury in humans, according to a new study. Thu, 24 Mar 2022 10:44:30 EDT //www.koonmotors.com/releases/2022/03/220324104430.htm //www.koonmotors.com/releases/2022/03/220316145725.htm Tumors can use an enzyme called ART1 to thwart antitumor immune cells, making the enzyme a promising new target for immunity-boosting cancer treatments, according to a new study. Wed, 16 Mar 2022 14:57:25 EDT //www.koonmotors.com/releases/2022/03/220316145725.htm //www.koonmotors.com/releases/2022/02/220224112606.htm The treatment of cancer could be revolutionized by the discovery that existing drugs, used to treat depression and heart disease, could reverse key changes in cancer cells that are associated with their ability to spread. Thu, 24 Feb 2022 11:26:06 EST //www.koonmotors.com/releases/2022/02/220224112606.htm //www.koonmotors.com/releases/2022/02/220224091119.htm Scientists say the unexpected discovery about small-cell lung cancer could lead to new treatment approaches for that cancer and other forms of cancer as well. Thu, 24 Feb 2022 09:11:19 EST //www.koonmotors.com/releases/2022/02/220224091119.htm //www.koonmotors.com/releases/2022/02/220203192317.htm 吸食大麻会导致肺损伤,但different way to tobacco, new research has found. The findings come from the long-running Dunedin Multidisciplinary Health and Development Study, which has documented cannabis use and measured lung function throughout adult life up to age 45 in more than 1,000 individuals born in Dunedin, New Zealand in 1972/73. Thu, 03 Feb 2022 19:23:17 EST //www.koonmotors.com/releases/2022/02/220203192317.htm //www.koonmotors.com/releases/2022/02/220202134654.htm A combined treatment strategy targeting SARS-CoV-2 symptoms and severe lung tissue injury is essential to minimize lung sequelae -- chronic complications resulting from COVID-19 infection, according to a new review article. Wed, 02 Feb 2022 13:46:54 EST //www.koonmotors.com/releases/2022/02/220202134654.htm //www.koonmotors.com/releases/2022/01/220112105620.htm From our first breath, our lungs are exposed to microorganisms, such as bacteria and viruses. Thanks to immune cells in the lungs, so-called macrophages, we are protected from most infections at an early age. Researchers now show how lung macrophages develop; new findings that can help to reduce organ damage and that are significant for the continued development of important lung disease treatments. Wed, 12 Jan 2022 10:56:20 EST //www.koonmotors.com/releases/2022/01/220112105620.htm //www.koonmotors.com/releases/2022/01/220107160509.htm A blood test, combined with a risk model based on an individual's history, more accurately determines who is likely to benefit from lung cancer screening than the current U.S. recommendation. Fri, 07 Jan 2022 16:05:09 EST //www.koonmotors.com/releases/2022/01/220107160509.htm //www.koonmotors.com/releases/2021/12/211216145923.htm Researchers have discovered that a nanoparticle therapeutic enhances cancer immunotherapy and is a possible new approach in treating malignant pleural effusion (MPE). MPE is the accumulation of fluid between the chest wall and lungs and is accompanied by malignant cells and/or tumors. Thu, 16 Dec 2021 14:59:23 EST //www.koonmotors.com/releases/2021/12/211216145923.htm //www.koonmotors.com/releases/2021/12/211213133342.htm Researchers have identified novel changes in gene network interactions associated with cancer that may lead to new treatment targets for chemotherapy. Their work shows that more than 90 percent of changes in gene network interactions in nine types of cancer studied are not detectable by current tests focused on changes in gene expression. Mon, 13 Dec 2021 13:33:42 EST //www.koonmotors.com/releases/2021/12/211213133342.htm //www.koonmotors.com/releases/2021/12/211209124231.htm In the past decade, immunotherapy has helped save the lives of many cancer patients, many with lung cancer, who might have otherwise faced almost certain death sentences. However, only about 20% of patients who received immune therapies -- designed to enhance or override natural limitations on immune system response -- saw sustained benefits from treatment. Now Yale scientists have helped identify crucial ways that immune system cells congregate and communicate with each other to identify and eradicate tumors, an insight that can help improve these outcomes. Thu, 09 Dec 2021 12:42:31 EST //www.koonmotors.com/releases/2021/12/211209124231.htm