//www.koonmotors.com/news/health_medicine/kidney_disease/ Medical research on the kidney, causes and symptoms of kidney infections and failure. Find out about green tea and other food that affects the kidneys. Read about kidney stones and other kidney problems. en-us Wed, 06 Sep 2023 14:46:58 EDT Wed, 06 Sep 2023 14:46:58 EDT 60 //www.koonmotors.com/images/scidaily-logo-rss.png//www.koonmotors.com/news/health_medicine/kidney_disease/ For more science news, visit ScienceDaily. //www.koonmotors.com/releases/2023/08/230831121757.htm A novel study has identified a range of metabolic biomarkers that could help predict the risk of cancer. Thu, 31 Aug 2023 12:17:57 EDT //www.koonmotors.com/releases/2023/08/230831121757.htm //www.koonmotors.com/releases/2023/08/230830151744.htm A man-made antibody successfully prevented organ rejection when tested in primates that had undergone a kidney transplant, Duke Health researchers report. The finding clears the way for the new monoclonal antibody to move forward in human clinical trials. Wed, 30 Aug 2023 15:17:44 EDT //www.koonmotors.com/releases/2023/08/230830151744.htm //www.koonmotors.com/releases/2023/08/230829125942.htm Scientists are working on a new approach to treating kidney failure that could one day free people from needing dialysis or having to take harsh drugs to suppress their immune system after a transplant. Tue, 29 Aug 2023 12:59:42 EDT //www.koonmotors.com/releases/2023/08/230829125942.htm //www.koonmotors.com/releases/2023/08/230824120209.htm High urine levels of adenine, a metabolite produced in the kidney, were associated with a higher risk of kidney failure in three international research cohorts. Thu, 24 Aug 2023 12:02:09 EDT //www.koonmotors.com/releases/2023/08/230824120209.htm //www.koonmotors.com/releases/2023/08/230821153204.htm An analysis of a clinical trial of more than 2,500 people with Type 2 diabetes and kidney disease found that high levels of four biomarkers are strongly predictive for the development of heart and kidney issues. Mon, 21 Aug 2023 15:32:04 EDT //www.koonmotors.com/releases/2023/08/230821153204.htm //www.koonmotors.com/releases/2023/08/230816114156.htm Surgeons have transplanted a genetically engineered pig kidney that continues to function well after 32 days in a man declared dead by neurologic criteria and maintained with a beating heart on ventilator support. This represents the longest period that a gene-edited pig kidney has functioned in a human, and the latest step toward the advent of an alternate, sustainable supply of organs for transplant. Wed, 16 Aug 2023 11:41:56 EDT //www.koonmotors.com/releases/2023/08/230816114156.htm //www.koonmotors.com/releases/2023/08/230814122255.htm A new study reveals findings from over 800 clinical assays performed for kidney patients with MiTF family gene mutations. Mon, 14 Aug 2023 12:22:55 EDT //www.koonmotors.com/releases/2023/08/230814122255.htm //www.koonmotors.com/releases/2023/08/230810110340.htm Researchers have made a remarkable step forward in finding a potential cure for a type of childhood kidney disease. Thu, 10 Aug 2023 11:03:40 EDT //www.koonmotors.com/releases/2023/08/230810110340.htm //www.koonmotors.com/releases/2023/08/230801105029.htm Researchers found that patients with persistently high levels of urinary albumin excretion in the long term are at high risk of new-onset heart failure. Preventive treatment associated with the lowering of urinary albumin excretion levels in these patients could reduce the risk of later heart failure or mortality. Tue, 01 Aug 2023 10:50:29 EDT //www.koonmotors.com/releases/2023/08/230801105029.htm //www.koonmotors.com/releases/2023/07/230724122717.htm A protein that transports lipid into cells reveals clues to treating a major health problem affecting kidneys. Mon, 24 Jul 2023 12:27:17 EDT //www.koonmotors.com/releases/2023/07/230724122717.htm //www.koonmotors.com/releases/2023/07/230719112603.htm What causes certain individuals who experience a sudden decline in kidney function to develop kidney disease while others recover? A new study co-led by bioengineers could provide detailed insight -- at the level of individual cells -- into the underlying factors contributing to these divergent outcomes. Wed, 19 Jul 2023 11:26:03 EDT //www.koonmotors.com/releases/2023/07/230719112603.htm //www.koonmotors.com/releases/2023/07/230713192852.htm Scientists have discovered a previously unknown 'housekeeping' process in kidney cells that ejects unwanted content, resulting in cells that rejuvenate themselves and remain functioning and healthy. The self-renewal process, which is fundamentally different from how other bodily tissues are thought to regenerate, helps explain how, barring injury or disease, the kidneys can remain healthy for a lifetime. Thu, 13 Jul 2023 19:28:52 EDT //www.koonmotors.com/releases/2023/07/230713192852.htm //www.koonmotors.com/releases/2023/06/230623161123.htm The discovery of new genes linked to IgA nephropathy, a common kidney disease, confirms the idea that the immune system drives the disease. Fri, 23 Jun 2023 16:11:23 EDT //www.koonmotors.com/releases/2023/06/230623161123.htm //www.koonmotors.com/releases/2023/02/230228113810.htm A new device that calms overactive kidney nerves with ultrasound consistently lowered blood pressure in patients with uncontrolled hypertension, researchers have found. Tue, 28 Feb 2023 11:38:10 EST //www.koonmotors.com/releases/2023/02/230228113810.htm //www.koonmotors.com/releases/2023/02/230205081321.htm Something you maybe never thought of -- dolphins get kidney stones just like people! Now a researcher is reporting a new method to control the growth of ammonium urate crystals, the substance known to cause kidney stones in dolphins and the findings may not only help dolphins but may also have implications for the pharmaceutical industry. Sun, 05 Feb 2023 08:13:21 EST //www.koonmotors.com/releases/2023/02/230205081321.htm //www.koonmotors.com/releases/2023/01/230130090355.htm 钾水平过高或o low can be fatal. A new mathematical model sheds light on the often mysterious ways the body regulates this important electrolyte. Mon, 30 Jan 2023 09:03:55 EST //www.koonmotors.com/releases/2023/01/230130090355.htm //www.koonmotors.com/releases/2022/12/221202112521.htm A study sheds new light on our understanding of the metabolism in the kidneys, and how to use it for instance against SARS-CoV-2 protection. Fri, 02 Dec 2022 11:25:21 EST //www.koonmotors.com/releases/2022/12/221202112521.htm //www.koonmotors.com/releases/2022/11/221130114535.htm Researchers found an existing drug may help decrease side effects of cisplatin, a widely used cancer treatment that was discovered in 1965. Wed, 30 Nov 2022 11:45:35 EST //www.koonmotors.com/releases/2022/11/221130114535.htm //www.koonmotors.com/releases/2022/11/221109151915.htm Early diagnosis of chronic kidney disease (CKD) is key to managing progression of the disease. A new technique analyzing urine extracellular vesicles (uEVs) -- cell-derived nanoscale spherical structures involved in multiple biological functions -- in urine samples identifies changes in the kidneys earlier than conventional methods and can also predict renal function decline. Wed, 09 Nov 2022 15:19:15 EST //www.koonmotors.com/releases/2022/11/221109151915.htm //www.koonmotors.com/releases/2022/11/221108120424.htm 在两性之间的战争,女人打男人的寡糖r ability to recover from kidney injury, but the reasons are not well understood. A study provides some insights: Females, it turns out, have an advantage at the molecular level that protects them from a form of cell death that occurs in injured kidneys. This protection could be exploited as a potential therapeutic. Tue, 08 Nov 2022 12:04:24 EST //www.koonmotors.com/releases/2022/11/221108120424.htm //www.koonmotors.com/releases/2022/10/221031104450.htm When individuals with varying degrees of chronic kidney disease who were not on dialysis answered annual questionnaires about their symptoms, researchers found that one-third could be categorized as having a 'Worse symptom score and worsening trajectory' of symptoms. These patients had especially high risks of later needing dialysis and of dying before dialysis initiation. Mon, 31 Oct 2022 10:44:50 EDT //www.koonmotors.com/releases/2022/10/221031104450.htm //www.koonmotors.com/releases/2022/10/221025090452.htm A big group of bacteria found in our soil, our water and our shower heads are harmless for most of us, but a new study indicates they are associated with an increased risk of dying in individuals whose kidneys have failed. Tue, 25 Oct 2022 09:04:52 EDT //www.koonmotors.com/releases/2022/10/221025090452.htm //www.koonmotors.com/releases/2022/10/221018220426.htm Virologists have reverse-engineered an elusive virus linked to chronic kidney disease in cats and described its mechanism of infection, outlining the zoonotic potential of RNA viruses in the post-measles era. Tue, 18 Oct 2022 22:04:26 EDT //www.koonmotors.com/releases/2022/10/221018220426.htm //www.koonmotors.com/releases/2022/10/221017142455.htm Among patients with kidney cancer, the activity of four specific genes in the cancer cells seems to be able to predict the risk of the tumor spreading and the patient's chances of survival. Mon, 17 Oct 2022 14:24:55 EDT //www.koonmotors.com/releases/2022/10/221017142455.htm //www.koonmotors.com/releases/2022/10/221007190634.htm A new technique which combines the use of two ultrasound technologies may offer an option to move kidney stones out of the ureter with minimal pain and no anesthesia, according to a new feasibility study. Fri, 07 Oct 2022 19:06:34 EDT //www.koonmotors.com/releases/2022/10/221007190634.htm //www.koonmotors.com/releases/2022/09/220920100757.htm Using equations to calculate kidney function that do not include race adjustments would result in Black patients gaining time on the transplant waitlist before their kidneys fail that matched similar durations for white patients, according to a new study. Tue, 20 Sep 2022 10:07:57 EDT //www.koonmotors.com/releases/2022/09/220920100757.htm //www.koonmotors.com/releases/2022/09/220916112457.htm It is commonly believed that patients with chronic kidney disease should limit their protein intake given that excessive protein worsens kidney function. However, a new study indicates that changes in skeletal muscle mass are positively correlated with protein intake, suggesting the necessity of adequate protein intake to improve muscle mass after kidney transplantation. Fri, 16 Sep 2022 11:24:57 EDT //www.koonmotors.com/releases/2022/09/220916112457.htm //www.koonmotors.com/releases/2022/09/220916112346.htm Blocking the inhibition of PKD1 and PKD2 gene expression by deleting a binding site for microRNAs hindered the formation and growth of kidney cysts in autosomal dominant polycystic kidney disease (ADPKD) models, researchers reported. The findings suggest a strategy for gene therapy with the potential to arrest or cure ADPKD. Fri, 16 Sep 2022 11:23:46 EDT //www.koonmotors.com/releases/2022/09/220916112346.htm //www.koonmotors.com/releases/2022/09/220912112436.htm The levels of long-term blood sugar, HbA1c, can be used to accurately determine the risk of a person with type 1 diabetes developing eye- and kidney complications. A study has shown that this level should be lower than 53 mmol/mol (7%). The study has followed individuals for more than 30 years after the onset of type 1 diabetes. Mon, 12 Sep 2022 11:24:36 EDT //www.koonmotors.com/releases/2022/09/220912112436.htm //www.koonmotors.com/releases/2022/08/220831152820.htm New research confirms that ethnicity is a risk factor for developing kidney disease in people with Type 1 diabetes. The findings also show people of African-Caribbean heritage and living with diabetes have nearly a 60 percent greater risk of advanced kidney disease. Wed, 31 Aug 2022 15:28:20 EDT //www.koonmotors.com/releases/2022/08/220831152820.htm //www.koonmotors.com/releases/2022/08/220816175045.htm A genetic variation identified in a group of families who are prone to diabetes and kidney failure increases the levels of a type of fat, called ceramides. Therapeutics that prevent this change could be beneficial more broadly to anyone at risk for these conditions. Tue, 16 Aug 2022 17:50:45 EDT //www.koonmotors.com/releases/2022/08/220816175045.htm //www.koonmotors.com/releases/2022/08/220811163912.htm When surgeons remove patients' kidney stones, they typically leave behind small stones that appear not to be causing problems. However, a new randomized controlled study has shown that leaving these asymptomatic stones behind significantly increases the risk of a patient's relapse in the following five years. Thu, 11 Aug 2022 16:39:12 EDT //www.koonmotors.com/releases/2022/08/220811163912.htm //www.koonmotors.com/releases/2022/08/220801102923.htm Kidney stones can cause not only excruciating pain but also are associated with chronic kidney disease, osteoporosis and cardiovascular disease. If you've experienced a kidney stone once, you have a 30% chance of having another kidney stone within five years. Mon, 01 Aug 2022 10:29:23 EDT //www.koonmotors.com/releases/2022/08/220801102923.htm //www.koonmotors.com/releases/2022/07/220729173207.htm Genetic mutations which cause a debilitating hereditary kidney disease affecting children and young adults have been fixed in patient-derived kidney cells using a potentially game-changing DNA repair-kit. Fri, 29 Jul 2022 17:32:07 EDT //www.koonmotors.com/releases/2022/07/220729173207.htm //www.koonmotors.com/releases/2022/07/220718094435.htm Adding immunotherapy to standard anti-rejection medication could change the lives of thousands of kidney transplant patients with incurable cancer, as new research shows it can reduce this risk of organ rejection and eliminate cancer in a quarter of patients. Mon, 18 Jul 2022 09:44:35 EDT //www.koonmotors.com/releases/2022/07/220718094435.htm //www.koonmotors.com/releases/2022/07/220713152903.htm New research indicates that the polycystin-2 protein in cells' endoplasmic reticulum is important for maintaining kidney health, and its lack can contribute to autosomal dominant polycystic kidney disease. Wed, 13 Jul 2022 15:29:03 EDT //www.koonmotors.com/releases/2022/07/220713152903.htm //www.koonmotors.com/releases/2022/07/220707141850.htm 科学家hsve生成简单kidney-like structures called organoids and used them to identify potential drugs to treat adult-onset polycystic kidney disease. To accelerate the quest for new treatments for ADPKD, researchers used pluripotent stem cells to grow organoids consisting of one or two structures resembling the kidney's filtering units, known as nephrons. To make the organoids useful for studying ADPKD, the scientists used CRISPR/Cas9 gene editing to inactivate PKD1 or PKD2. As anticipated, the gene-edited organoids began to form cysts. After testing a collection of 247 enzyme inhibitor compounds on the organoids, the scientists found nine that inhibited the growth of the cysts, without stunting the overall growth of the organoids. One compound, quinazoline, was particularly effective. Thu, 07 Jul 2022 14:18:50 EDT //www.koonmotors.com/releases/2022/07/220707141850.htm //www.koonmotors.com/releases/2022/06/220627141453.htm Researchers have linked resistance to treatment for a deadly form of kidney cancer to low mitochondrial content in the cell. When the researchers increased the mitochondrial content with an inhibitor, the cancer cells responded to the treatment. Their findings offer hope for more targeted cancer drugs. Mon, 27 Jun 2022 14:14:53 EDT //www.koonmotors.com/releases/2022/06/220627141453.htm //www.koonmotors.com/releases/2022/06/220616142751.htm By analyzing thousands of genetic risk variants, a new algorithm may be able to predict your risk of developing chronic kidney disease decades before onset. Thu, 16 Jun 2022 14:27:51 EDT //www.koonmotors.com/releases/2022/06/220616142751.htm //www.koonmotors.com/releases/2022/06/220602114210.htm If you need another reason to start the day drinking a cup of joe, a recent study has revealed that consuming at least one cup of coffee a day may reduce the risk of acute kidney injury (AKI) when compared to those who do not drink coffee. Thu, 02 Jun 2022 11:42:10 EDT //www.koonmotors.com/releases/2022/06/220602114210.htm //www.koonmotors.com/releases/2022/05/220525102934.htm A new study supports the notion that patients with type 2 diabetes patient should be divided into subgroups and given individualized treatment. The study demonstrates that there are distinct epigenetic differences between different groups of patients with type 2 diabetes. The epigenetic markers are also associated with different risks of developing common complications in type 2 diabetes, such as stroke, heart attack and kidney disease. Wed, 25 May 2022 10:29:34 EDT //www.koonmotors.com/releases/2022/05/220525102934.htm //www.koonmotors.com/releases/2022/05/220519081112.htm A test for the common blood cancer multiple myeloma also holds clear clues that the patient has one of the most uncommon and deadly forms of this cancer, investigators say. Thu, 19 May 2022 08:11:12 EDT //www.koonmotors.com/releases/2022/05/220519081112.htm //www.koonmotors.com/releases/2022/05/220505085618.htm Anyone who is taking a diuretic and a renin-angiotensin system (RSA) inhibitor for high blood pressure should be cautious about also taking ibuprofen, according to new research. Thu, 05 May 2022 08:56:18 EDT //www.koonmotors.com/releases/2022/05/220505085618.htm //www.koonmotors.com/releases/2022/04/220425085722.htm 人的主要并发症的风险ate a kidney via laparoscopic surgery is minimal. That is the conclusion of a 20-year study of more than 3,000 living kidney donors. Only 2.5% of patients in the study experienced major complications, and all recovered completely. Mon, 25 Apr 2022 08:57:22 EDT //www.koonmotors.com/releases/2022/04/220425085722.htm //www.koonmotors.com/releases/2022/04/220425085719.htm The kidney carries out important functions via microscopic functional units called nephrons. Researchers are investigating which factors control the formation and function of specific segments of the nephron, called the distal nephron. Their findings could have implications in the treatment of kidney diseases. Mon, 25 Apr 2022 08:57:19 EDT //www.koonmotors.com/releases/2022/04/220425085719.htm //www.koonmotors.com/releases/2022/04/220421181201.htm Researchers showed that SARS-CoV-2 can infect kidney cells via multiple binding sites and hijack the cell's machinery to replicate, causing injury and COVID-19-associated kidney disease. Thu, 21 Apr 2022 18:12:01 EDT //www.koonmotors.com/releases/2022/04/220421181201.htm //www.koonmotors.com/releases/2022/04/220412095324.htm Best known therapeutically as a treatment for bipolar disorder, lithium has long intrigued researchers with its potential age-defying properties. New research has found low-dose lithium can block an an enzyme that is associated with cellular aging in the kidney and a decline in kidney function. If validated in pilot studies and eventually large-scale clinical trials, lithium may emerge as an effective anti-aging medication for the kidney. Tue, 12 Apr 2022 09:53:24 EDT //www.koonmotors.com/releases/2022/04/220412095324.htm //www.koonmotors.com/releases/2022/04/220411133504.htm A compound called SCR7 supports DNA repair to prevent irreparable tissue damage and chronic kidney disease progression. Mon, 11 Apr 2022 13:35:04 EDT //www.koonmotors.com/releases/2022/04/220411133504.htm //www.koonmotors.com/releases/2022/03/220325093909.htm While kidney function is known to be related to bleeding event risk, researchers conducted a post-hoc subgroup analysis of the Atrial Fibrillation and Ischemic Events with Rivaroxaban in Patients with Stable Coronary Artery Disease (AFIRE) trial to determine the impact of kidney function on the risk of recurrent bleeding events during antithrombotic therapy. Their analysis revealed that the effect of kidney function on recurrent bleeding risk events was quite large for patients undergoing this treatment. Fri, 25 Mar 2022 09:39:09 EDT //www.koonmotors.com/releases/2022/03/220325093909.htm //www.koonmotors.com/releases/2022/03/220323093641.htm Researchers have conducted a retrospective study of over 3100 people with chronic kidney disease to evaluate the association between mineralocorticoid receptor antagonist (MRA) use and renal outcomes. The analysis revealed an association between MRA use and a reduced risk for the initiation of renal replacement therapy across multiple subgroups of patients with chronic kidney disease. These findings reinforce the use of MRAs in treatment plans for various groups of people with chronic kidney disease who are not undergoing dialysis. Wed, 23 Mar 2022 09:36:41 EDT //www.koonmotors.com/releases/2022/03/220323093641.htm //www.koonmotors.com/releases/2022/03/220309104443.htm Tests using a preclinical model of Alport syndrome suggests that turning off a cell signalling protein may significantly prolong life by preventing kidney scarring. Wed, 09 Mar 2022 10:44:43 EST //www.koonmotors.com/releases/2022/03/220309104443.htm //www.koonmotors.com/releases/2022/02/220201074530.htm Researchers have created a complex kidney tissue solely from mouse embryonic stem cells. These organoids could lead the way to better kidney research and, eventually, artificial kidneys for human transplant. Tue, 01 Feb 2022 07:45:30 EST //www.koonmotors.com/releases/2022/02/220201074530.htm //www.koonmotors.com/releases/2022/01/220120091128.htm Researchers have announced the first peer-reviewed research outlining the successful transplant of genetically modified, clinical-grade pig kidneys into a brain-dead human individual, replacing the recipient's native kidneys. These positive results demonstrate how xenotransplantation could address the worldwide organ shortage crisis. Thu, 20 Jan 2022 09:11:28 EST //www.koonmotors.com/releases/2022/01/220120091128.htm //www.koonmotors.com/releases/2022/01/220119121353.htm A high protein diet appears linked to kidney disease and shortened lifespans for captive polar bears, a relationship similarly suspected in humans. A careful look at what zoos have fed polar bears revealed they mostly offered a diet intended for big cats, containing about 2-3 parts protein to 1-part fat, a reversal from what was observed in the wild. Wed, 19 Jan 2022 12:13:53 EST //www.koonmotors.com/releases/2022/01/220119121353.htm //www.koonmotors.com/releases/2022/01/220112094027.htm New kidney research is raising concerns that long-term use of ACE inhibitors and other drugs commonly prescribed to treat high-blood pressure and heart failure could be contributing to kidney damage. Wed, 12 Jan 2022 09:40:27 EST //www.koonmotors.com/releases/2022/01/220112094027.htm //www.koonmotors.com/releases/2022/01/220105134515.htm Researchers have developed a CRISPR-based assay that can sensitively and non-invasively detect a biomarker of acute kidney rejection in urine. This could someday help diagnose rejection earlier and without a biopsy. Wed, 05 Jan 2022 13:45:15 EST //www.koonmotors.com/releases/2022/01/220105134515.htm //www.koonmotors.com/releases/2021/12/211213095020.htm Using cannabis alongside other drugs may come with a significant risk of harmful drug-drug interactions, new research suggests. The researchers looked at cannabinoids--a group of substances found in the cannabis plant -- and their major metabolites found in cannabis users' blood and found that they interfere with two families of enzymes that help metabolize a wide range of drugs prescribed for a variety of conditions. As a result, either the drugs' positive effects might decrease or their negative effects might increase with too much building up in the body, causing unintended side effects such as toxicity or accidental overdose. While more research needs to be done, the authors said one early takeaway from these studies is that it's important to be careful when using cannabis with other prescription drugs. Mon, 13 Dec 2021 09:50:20 EST //www.koonmotors.com/releases/2021/12/211213095020.htm //www.koonmotors.com/releases/2021/12/211208110247.htm A team of researchers has established a new method to measure glomerular filtration rate (GFR), a primary kidney function, by calculating the clearance of D-serine. Wed, 08 Dec 2021 11:02:47 EST //www.koonmotors.com/releases/2021/12/211208110247.htm //www.koonmotors.com/releases/2021/11/211111171121.htm Medical researchers found that chlorthalidone was effective in lowering blood pressure in individuals with advanced kidney disease. Thu, 11 Nov 2021 17:11:21 EST //www.koonmotors.com/releases/2021/11/211111171121.htm //www.koonmotors.com/releases/2021/11/211108094238.htm Researchers now associate elevated levels of the protein galectin-1 with increased risk of developing type 2 diabetes about 18 years later. At the same time, this protein seems to be a protective factor for the kidneys among type 2 diabetes patients at high risk for diabetic nephropathy. Mon, 08 Nov 2021 09:42:38 EST //www.koonmotors.com/releases/2021/11/211108094238.htm