//www.koonmotors.com/news/health_medicine/joint_health/ Recent research on joint health and joint conditions, including arthritis, osteoarthritis, osteoporosis, new surgical techniques and procedures. en-us Sun, 10 Sep 2023 11:47:35 EDT Sun, 10 Sep 2023 11:47:35 EDT 60 //www.koonmotors.com/images/scidaily-logo-rss.png//www.koonmotors.com/news/health_medicine/joint_health/ 更多的科学新s, visit ScienceDaily. //www.koonmotors.com/releases/2023/08/230821232429.htm Mon, 21 Aug 2023 23:24:29 EDT //www.koonmotors.com/releases/2023/08/230821232429.htm //www.koonmotors.com/releases/2023/07/230721113151.htm The genetic changes that made it possible for humans to walk upright have been uncovered in a study that also shows how slight variations in skeletal proportions are linked to arthritis. Fri, 21 Jul 2023 11:31:51 EDT //www.koonmotors.com/releases/2023/07/230721113151.htm //www.koonmotors.com/releases/2023/07/230706124526.htm For the first time, scientists have shown that gut bacteria differences are associated with later development of juvenile idiopathic arthritis, a debilitating rheumatic childhood disease, and that these differences are present years before the disease is diagnosed. Thu, 06 Jul 2023 12:45:26 EDT //www.koonmotors.com/releases/2023/07/230706124526.htm //www.koonmotors.com/releases/2023/07/230705143002.htm Osteoarthritis is the most common degenerative joint disease, affecting 22% of adults over 40 globally. Although the condition has been extensively studied through a medical perspective, the molecular changes associated with osteoarthritis remain unclear. In a new study, researchers have used a combination of techniques to track the progression of the disease and the changes associated with it. Wed, 05 Jul 2023 14:30:02 EDT //www.koonmotors.com/releases/2023/07/230705143002.htm //www.koonmotors.com/releases/2023/06/230621121030.htm A gel that combines both stiffness and toughness is a step forward in the bid to create biodegradable implants for joint injuries, according to new research. Mimicking articular cartilage, found in our knee and hip joints, is challenging. This cartilage is key to smooth joint movement, and damage to it can cause pain, reduce function, and lead to arthritis. One potential solution is to implant artificial scaffolds made of proteins that help the cartilage regenerate itself as the scaffold biodegrades. How well the cartilage regenerates is linked to how well a scaffold can mimic the biological properties of cartilage, and to date, researchers have struggled to combine the seemingly incompatible properties of stiffness and toughness. Now, new research outlines a method to marry these properties in a biodegradable gel. Wed, 21 Jun 2023 12:10:30 EDT //www.koonmotors.com/releases/2023/06/230621121030.htm //www.koonmotors.com/releases/2023/04/230411150523.htm The exact mechanism of cartilage breakdown in osteoarthritis is unknown, but damage from mechanical stress with insufficient self-repair is believed to be the main culprit. The composition of synovial fluid, or joint lubricant, changes significantly: The concentration and molecular weight of hyaluronic acid tends to decrease. Researchers explore the disease-driven breakdown of hyaluronan and the mechanistic implications of these changes on the lubrication and subsequent wear of joints. Tue, 11 Apr 2023 15:05:23 EDT //www.koonmotors.com/releases/2023/04/230411150523.htm //www.koonmotors.com/releases/2023/04/230404114256.htm Being overweight may be physically changing the environment within people's joints, as new research suggests that obesity is promoting pro-inflammatory conditions which worsen arthritis. Tue, 04 Apr 2023 11:42:56 EDT //www.koonmotors.com/releases/2023/04/230404114256.htm //www.koonmotors.com/releases/2023/03/230301101513.htm Understanding how the knee joint environment affects cartilage cells is crucial for joint health. Knowledge of cell-driven cartilage degeneration mechanisms can support the development of effective pharmaceutical interventions for osteoarthritis. Researchers have now incorporated the influence of cells in a new numerical model to discover degeneration processes in mechanically loaded and inflamed cartilage. Wed, 01 Mar 2023 10:15:13 EST //www.koonmotors.com/releases/2023/03/230301101513.htm //www.koonmotors.com/releases/2023/02/230221113037.htm Strengthening hip muscles could be key to improve mobility in people with a below-the-knee amputation, new research has shown. Tue, 21 Feb 2023 11:30:37 EST //www.koonmotors.com/releases/2023/02/230221113037.htm //www.koonmotors.com/releases/2023/01/230112090947.htm Scientists delved into the relationship between gait function and knee extension velocity after total knee arthroplasty and compared the effects of various factors on walking. The results reveal that knee extension velocity, measured while seated, on the operated side was the most important determinant of gait function. These findings are expected to contribute to the development of new rehabilitation programs for efficient gait function improvement. Thu, 12 Jan 2023 09:09:47 EST //www.koonmotors.com/releases/2023/01/230112090947.htm //www.koonmotors.com/releases/2023/01/230110151001.htm Researchers develop an injectable hydrogel that treats infections around prosthetics without the problems caused by current treatments. The black phosphorus-enhanced gel has a porous structure, excellent injectability, and rapid self-healing properties. Tests show it has good stability and low toxicity to tissue cells, and irradiating the gel with near infrared light causes it to release silver ions. This process was highly efficient at inhibiting S. aureus, common bacteria that cause disease in humans. Tue, 10 Jan 2023 15:10:01 EST //www.koonmotors.com/releases/2023/01/230110151001.htm //www.koonmotors.com/releases/2023/01/230110103450.htm Researchers have identified a new mechanism behind knee osteoarthritis, showing that increased stiffening in the extracellular matrix led to a decrease in the Klotho 'longevity protein,' which led to damage in healthy cartilage cells. The findings may inform better treatment targets and increase understanding of other conditions caused by aging tissues in the body. Tue, 10 Jan 2023 10:34:50 EST //www.koonmotors.com/releases/2023/01/230110103450.htm //www.koonmotors.com/releases/2022/12/221221154703.htm A new study has identified that Talarozole, a drug that is known to increase retinoic acid, was able to prevent osteoarthritis (OA) in disease models. Wed, 21 Dec 2022 15:47:03 EST //www.koonmotors.com/releases/2022/12/221221154703.htm //www.koonmotors.com/releases/2022/12/221215161557.htm Researchers have developed an AI based neural network to detect an early knee osteoarthritis from x-ray images. AI was able to match a doctors' diagnosis in 87% of cases. The result is important because x-rays are the primary diagnostic method for early knee osteoarthritis. An early diagnosis can save the patient from unnecessary examinations, treatments and even knee joint replacement surgery. Thu, 15 Dec 2022 16:15:57 EST //www.koonmotors.com/releases/2022/12/221215161557.htm //www.koonmotors.com/releases/2022/12/221213180729.htm Large doses of opioids are commonly prescribed after total knee and hip arthroplasty to avoid call-ins for refills, but smaller doses can be just as effective. 星期二,2022年12月13日18:07:29 EST //www.koonmotors.com/releases/2022/12/221213180729.htm //www.koonmotors.com/releases/2022/12/221213121554.htm Scientists identify a new molecular model and potential therapeutic target for gout, the most common form of inflammatory arthritis. Tue, 13 Dec 2022 12:15:54 EST //www.koonmotors.com/releases/2022/12/221213121554.htm //www.koonmotors.com/releases/2022/12/221208114741.htm Commonly used drugs that reduce joint inflammation in patients with rheumatoid arthritis also reduce vascular inflammation and cardiovascular risk, finds a new study. Thu, 08 Dec 2022 11:47:41 EST //www.koonmotors.com/releases/2022/12/221208114741.htm //www.koonmotors.com/releases/2022/11/221123113333.htm Competing at elite level in sport is linked with an increased risk of developing osteoarthritis and joint pain in later life, a study suggests. One in four retired Olympians reported a diagnosis of osteoarthritis, the form of arthritis that causes changes in the joint and can lead to discomfort, pain and disability, the research found. Wed, 23 Nov 2022 11:33:33 EST //www.koonmotors.com/releases/2022/11/221123113333.htm //www.koonmotors.com/releases/2022/11/221118095415.htm So far, there no uniform guidelines have existed for the treatment of arthritis of the jaw, a potentially debilitating consequence of juvenile arthritis. Fri, 18 Nov 2022 09:54:15 EST //www.koonmotors.com/releases/2022/11/221118095415.htm //www.koonmotors.com/releases/2022/11/221114190554.htm Patients with advanced ankle osteoarthritis who undergo surgery see equally good outcomes from the two main surgical treatments for osteoarthritis, a new study has shown. Mon, 14 Nov 2022 19:05:54 EST //www.koonmotors.com/releases/2022/11/221114190554.htm //www.koonmotors.com/releases/2022/11/221104093255.htm The number of new diagnoses of rheumatoid arthritis fell by 20 percent in the first year of the COVID-19 pandemic, new research suggests. Fri, 04 Nov 2022 09:32:55 EDT //www.koonmotors.com/releases/2022/11/221104093255.htm //www.koonmotors.com/releases/2022/10/221006121128.htm An advanced design technique, used to develop components for aerospace and automotive industries, has been harnessed in the production of bespoke medical devices. Thu, 06 Oct 2022 12:11:28 EDT //www.koonmotors.com/releases/2022/10/221006121128.htm //www.koonmotors.com/releases/2022/09/220929133330.htm As well as causing considerable pain, rheumatoid arthritis (RA) can also trigger neuropsychiatric problems including memory impairment. Scientists have now examined the role of monoamine oxidase-B (MAO-B) in RA. MAO-B and related molecules were upregulated in patients' joints and the brain. Thu, 29 Sep 2022 13:33:30 EDT //www.koonmotors.com/releases/2022/09/220929133330.htm //www.koonmotors.com/releases/2022/09/220914140712.htm Improvements in pain, physical function and work productivity largely endure for at least seven years after bariatric surgery, despite some backsliding from the high levels of improvement seen in the years immediately following surgery, epidemiologists report. Wed, 14 Sep 2022 14:07:12 EDT //www.koonmotors.com/releases/2022/09/220914140712.htm //www.koonmotors.com/releases/2022/09/220908100052.htm 科学家已经分离出一种蛋白质被称为sulfatase-2 that plays a critical role in the damage caused by rheumatoid arthritis. The researchers' discovery sheds new light on the molecular processes that drive inflammation seen in rheumatoid arthritis. It could also someday lead to improved treatment of the disease, which currently has no cure. Thu, 08 Sep 2022 10:00:52 EDT //www.koonmotors.com/releases/2022/09/220908100052.htm //www.koonmotors.com/releases/2022/08/220808211744.htm 研究人员发现,细胞膜的方式king, or gait, of Japanese children develops differently from that of children in other countries. Mon, 08 Aug 2022 21:17:44 EDT //www.koonmotors.com/releases/2022/08/220808211744.htm //www.koonmotors.com/releases/2022/08/220802121724.htm Experts have found that the risk of heart attacks and strokes temporarily increases in the four months after a gout flare. The research showed that gout patients who suffered from a heart attack or stroke were twice as likely to have had a gout flare in the 60 days prior to the event, and one and a half times more likely to have a gout flare in the 61-120 days prior. Tue, 02 Aug 2022 12:17:24 EDT //www.koonmotors.com/releases/2022/08/220802121724.htm //www.koonmotors.com/releases/2022/06/220608161402.htm A new study reveals that walking for exercise can reduce new frequent knee pain among people age 50 and older diagnosed with knee osteoarthritis, the most common form of arthritis. Additionally, findings from the study indicate that walking for exercise may be an effective treatment to slow the damage that occurs within the joint. Wed, 08 Jun 2022 16:14:02 EDT //www.koonmotors.com/releases/2022/06/220608161402.htm //www.koonmotors.com/releases/2022/05/220517112216.htm Adenosine triphosphate (ATP) secreted from sensory neuron-interneuron crosstalk is key to the spreading of inflammation across joints, acting as a neurotransmitter and inflammation enhancer. Tue, 17 May 2022 11:22:16 EDT //www.koonmotors.com/releases/2022/05/220517112216.htm //www.koonmotors.com/releases/2022/05/220506113322.htm To provide a convenient tool for the early detection of injuries, researchers have developed a portable MRI device for diagnosing cartilage damage in the wrist. Using this device, the researchers imaged the wrists of tennis players at a tennis school. Several athletes were found to have cartilage damage without any other symptoms of an injury. Thus, this device provides a convenient early screening tool to help prevent further injury or damage. Fri, 06 May 2022 11:33:22 EDT //www.koonmotors.com/releases/2022/05/220506113322.htm //www.koonmotors.com/releases/2022/02/220214154902.htm Scientists have teamed up to explore cartilage tissue's unique properties with the hopes of improving osteoarthritis diagnosis and treatment. Mon, 14 Feb 2022 15:49:02 EST //www.koonmotors.com/releases/2022/02/220214154902.htm //www.koonmotors.com/releases/2022/02/220209155008.htm An expert in autoimmune diseases and systemic lupus erythematosus has identified potential biomarkers for neuropsychiatric symptoms of lupus after conducting a large-scale protein study. Wed, 09 Feb 2022 15:50:08 EST //www.koonmotors.com/releases/2022/02/220209155008.htm //www.koonmotors.com/releases/2022/01/220129084222.htm With one in five people experiencing ongoing pain long after knee replacement surgery, new research has shown a way to help reduce people's continuing pain that could also save time and money too. Sat, 29 Jan 2022 08:42:22 EST //www.koonmotors.com/releases/2022/01/220129084222.htm //www.koonmotors.com/releases/2022/01/220125112527.htm A technique that uses ultrasound images to determine the depth and shape of the hip socket can accurately predict which infants with hip dysplasia will develop normal hip structure and which remain dysplastic, according to a new study. Researchers said statistical shape modeling improves on existing techniques and could spare many infants from unnecessary treatment. Tue, 25 Jan 2022 11:25:27 EST //www.koonmotors.com/releases/2022/01/220125112527.htm //www.koonmotors.com/releases/2022/01/220113111515.htm With the Winter Olympics approaching, many people will soon be tuning in to watch events that take place on ice, such as figure skating, speed skating and ice hockey. An ultrathin, super-lubricating layer of water on the ice's surface is essential for skaters' graceful glides. Inspired by this surface, researchers have developed a treatment for osteoarthritis that enhances lubrication and reduces friction and inflammation in a rat model of the disease. Thu, 13 Jan 2022 11:15:15 EST //www.koonmotors.com/releases/2022/01/220113111515.htm //www.koonmotors.com/releases/2022/01/220112145042.htm Bioengineers successfully regrew cartilage in a rabbit's knee, a promising hop toward healing joints in humans. Wed, 12 Jan 2022 14:50:42 EST //www.koonmotors.com/releases/2022/01/220112145042.htm //www.koonmotors.com/releases/2022/01/220104123556.htm 研究人员发现,有一种of autoimmune disease can lead to another. Tue, 04 Jan 2022 12:35:56 EST //www.koonmotors.com/releases/2022/01/220104123556.htm //www.koonmotors.com/releases/2021/12/211215113234.htm Researchers used gallic acid, an antioxidant found in gallnuts, green tea and other plants, and applied a stretching mechanism to human cartilage cells taken from arthritic knees that mimics the stretching that occurs when walking. The combination not only decreased arthritis inflammation markers in the cells but improved the production of desired proteins normally found in healthy cartilage. While still at an early stage, the findings suggest a new procedure could be developed to treat cartilage cells extracted from a patient to grow a supply of cells or a tissue to be re-implanted. Wed, 15 Dec 2021 11:32:34 EST //www.koonmotors.com/releases/2021/12/211215113234.htm //www.koonmotors.com/releases/2021/12/211208102600.htm 一项新的研究发现,老年人服用药物used to treat anxiety and insomnia -- nitrazepam -- as well as those on antidepressants, are twice as likely to suffer postoperative delirium after hip and knee surgery. Wed, 08 Dec 2021 10:26:00 EST //www.koonmotors.com/releases/2021/12/211208102600.htm //www.koonmotors.com/releases/2021/11/211129172742.htm Combined diet and exercise Telehealth program saw 80 per cent of participants experience reduced knee pain with an average weight loss of approximately 10.2 per cent. Mon, 29 Nov 2021 17:27:42 EST //www.koonmotors.com/releases/2021/11/211129172742.htm //www.koonmotors.com/releases/2021/11/211117100053.htm Exercise increases the body's own cannabis-like substances, which in turn helps reduce inflammation and could potentially help treat certain conditions such as arthritis, cancer and heart disease. Wed, 17 Nov 2021 10:00:53 EST //www.koonmotors.com/releases/2021/11/211117100053.htm //www.koonmotors.com/releases/2021/11/211104162636.htm Blocking a molecule that draws sensory nerves into musculoskeletal injuries prevents heterotopic ossification (HO), a process in which bone abnormally grows in soft tissue during healing, researchers reported. The findings suggest that drugs currently being tested in clinical trials to inhibit this molecule for pain relief could also protect against this challenging condition. Thu, 04 Nov 2021 16:26:36 EDT //www.koonmotors.com/releases/2021/11/211104162636.htm //www.koonmotors.com/releases/2021/11/211103082559.htm In a recent analysis, investigators did not find any link between the amount and duration of physical activity with individuals' risk of developing knee osteoarthritis. Wed, 03 Nov 2021 08:25:59 EDT //www.koonmotors.com/releases/2021/11/211103082559.htm //www.koonmotors.com/releases/2021/10/211027122141.htm Even low levels of physical therapy were associated with lower risk of chronic opioid use after total knee replacement. The team's analysis of over 67,000 patient records revealed that the longer a patient waits to start physical therapy, the greater the eventual odds of chronic opioid use. Wed, 27 Oct 2021 12:21:41 EDT //www.koonmotors.com/releases/2021/10/211027122141.htm //www.koonmotors.com/releases/2021/10/211014100223.htm A new discovery about osteoporosis suggests a potential treatment target for that brittle-bone disease and for bone loss from rheumatoid arthritis. Thu, 14 Oct 2021 10:02:23 EDT //www.koonmotors.com/releases/2021/10/211014100223.htm //www.koonmotors.com/releases/2021/09/210907110732.htm New recommendations will help provide more reliable, reproducible results for MRI-based measurements of cartilage degeneration in the knee, helping to slow down disease and prevent progression to irreversible osteoarthritis. Tue, 07 Sep 2021 11:07:32 EDT //www.koonmotors.com/releases/2021/09/210907110732.htm //www.koonmotors.com/releases/2021/09/210901142723.htm Cartilage cells from the nasal septum can not only help repair cartilage injuries in the knee -- according to researchers, they can also withstand the chronic inflammatory tissue environment in osteoarthritis and even counteract the inflammation. Wed, 01 Sep 2021 14:27:23 EDT //www.koonmotors.com/releases/2021/09/210901142723.htm //www.koonmotors.com/releases/2021/08/210830163952.htm A pilot study combined wearable technology and patient-reported outcomes to assess the efficacy of platelet-rich plasma (PRP) treatment in osteoarthritis (OA), finding significant improvements. Mon, 30 Aug 2021 16:39:52 EDT //www.koonmotors.com/releases/2021/08/210830163952.htm //www.koonmotors.com/releases/2021/08/210826111642.htm Researchers have found new genetic risk factors for osteoarthritis and identified novel drug targets. Their finding is a milestone towards the development of the first ever curative treatment for osteoarthritis. Thu, 26 Aug 2021 11:16:42 EDT //www.koonmotors.com/releases/2021/08/210826111642.htm //www.koonmotors.com/releases/2021/07/210714110546.htm Pioneering 'printed metal' procedure to create bespoke treatment for early knee osteoarthritis set to be trialed in the UK following MHRA approval. Wed, 14 Jul 2021 11:05:46 EDT //www.koonmotors.com/releases/2021/07/210714110546.htm //www.koonmotors.com/releases/2021/07/210712092216.htm A new study has found that greater trunk flexion has significant impact on stride length, joint movements, and ground reaction forces. How you lean may be one of the contributors to your knee pain, medial tibial stress syndrome, or back pain. Mon, 12 Jul 2021 09:22:16 EDT //www.koonmotors.com/releases/2021/07/210712092216.htm //www.koonmotors.com/releases/2021/06/210622161046.htm Diet rich in sugar and fat leads to disruption in the gut's microbial culture and contributes to inflammatory skin diseases such as psoriasis. Research shows that switching to a more balanced diet restores the gut's health and suppresses inflammation. Tue, 22 Jun 2021 16:10:46 EDT //www.koonmotors.com/releases/2021/06/210622161046.htm //www.koonmotors.com/releases/2021/06/210604122445.htm According to a pilot study, the flexed elbow valgus external rotation (FEVER) view can improve MRI evaluation of the ulnar collateral ligament (UCL) in Major League Baseball pitchers. The increased joint space width confirms elbow valgus stress with FEVER view. Diagnostic confidence increased, and additional UCLs were identified as abnormal. Fri, 04 Jun 2021 12:24:45 EDT //www.koonmotors.com/releases/2021/06/210604122445.htm //www.koonmotors.com/releases/2021/04/210420092901.htm Researchers report that 50.2 million (20.5 percent) U.S. adults experience chronic pain based on analysis of the new NHIS data. They estimated the total value of lost productivity due to chronic pain to be nearly $300 billion annually. Tue, 20 Apr 2021 09:29:01 EDT //www.koonmotors.com/releases/2021/04/210420092901.htm //www.koonmotors.com/releases/2021/03/210323090559.htm Taking into consideration costs of forgoing versus pursuing total knee replacement, researchers found that across older and younger age groups, TKR is a cost-effective treatment for these patients. Tue, 23 Mar 2021 09:05:59 EDT //www.koonmotors.com/releases/2021/03/210323090559.htm //www.koonmotors.com/releases/2021/03/210322175002.htm An unfortunate biological 'feed-forward' loop drives cartilage cells in an arthritic joint to actually contribute to progression of the disease, say researchers. Excessive loading under inflammatory conditions can create a situation that can lead to progressive cartilage degeneration. Mon, 22 Mar 2021 17:50:02 EDT //www.koonmotors.com/releases/2021/03/210322175002.htm //www.koonmotors.com/releases/2021/02/210224090634.htm Rheumatoid arthritis is a chronic inflammatory disorder marked by joint pain, swelling and damage. Although medications, such as steroids, anti-inflammatory drugs and immunosuppressants, can help slow joint destruction and relieve pain, they have side effects and aren't completely successful. Now, researchers have developed magnesium-based micromotors propelled by hydrogen bubbles, which improved rheumatoid arthritis symptoms when injected into the joints of rats. Wed, 24 Feb 2021 09:06:34 EST //www.koonmotors.com/releases/2021/02/210224090634.htm //www.koonmotors.com/releases/2021/01/210120204039.htm Antidepressant drugs are largely ineffective for back and osteoarthritis pain, despite being widely used for these conditions, suggests a review of the evidence. Wed, 20 Jan 2021 20:40:39 EST //www.koonmotors.com/releases/2021/01/210120204039.htm //www.koonmotors.com/releases/2021/01/210115115244.htm In a mouse study, researchers used nanotechnology and previous knowledge of a protein pathway to significantly reduce knee cartilage degeneration and pain. Fri, 15 Jan 2021 11:52:44 EST //www.koonmotors.com/releases/2021/01/210115115244.htm //www.koonmotors.com/releases/2021/01/210112110116.htm Scientists have now demonstrated a connection between inferior physical fitness in young adults and elevated risk of the autoimmune disease psoriasis. For the male recruits to compulsory military training who were rated as the least fit, the risk of developing psoriasis later was 35 percent higher than for the fittest. Tue, 12 Jan 2021 11:01:16 EST //www.koonmotors.com/releases/2021/01/210112110116.htm