//www.koonmotors.com/news/health_medicine/crohn's_disease/ Crohn's disease. Read the latest research on Crohn's disease: risk factors, reducing flare ups, and new treatment options. en-us Wed, 06 Sep 2023 14:46:21 EDT Wed, 06 Sep 2023 14:46:21 EDT 60 //www.koonmotors.com/images/scidaily-logo-rss.png//www.koonmotors.com/news/health_medicine/crohn's_disease/ For more science news, visit ScienceDaily. //www.koonmotors.com/releases/2023/07/230728121132.htm Research found that direct injection of neonatal mesenchymal stem cells, derived from heart tissue discarded during surgery, reduces intestinal inflammation and promotes wound healing in a mouse model of Crohn's disease-like ileitis, an illness marked by chronic intestinal inflammation and progressive tissue damage. The study offers a promising new and alternative treatment approach that avoids the pitfalls of current Crohn's disease medications, including diminishing effectiveness, severe side effects and increased risk of gastrointestinal dysfunction. Fri, 28 Jul 2023 12:11:32 EDT //www.koonmotors.com/releases/2023/07/230728121132.htm //www.koonmotors.com/releases/2023/07/230717115853.htm Chronic inflammatory bowel disease (IBD), such as Crohn's disease and ulcerative colitis, is on the rise worldwide. The benefits of current medications are limited by problematic side effects. A research team has now introduced a new method of treatment. It is based on nanoparticles that mimic a special carbohydrate layer (glycocalyx) located on inflamed bowel cells, and which trigger anti-inflammatory effects in the diseased sites in the intestine. Mon, 17 Jul 2023 11:58:53 EDT //www.koonmotors.com/releases/2023/07/230717115853.htm //www.koonmotors.com/releases/2023/07/230705115125.htm A study of the genetic variation that makes mice more susceptible to bowel inflammation after a high-fat diet has identified candidate genes which may drive inflammatory bowel disease (IBD) in humans. Wed, 05 Jul 2023 11:51:25 EDT //www.koonmotors.com/releases/2023/07/230705115125.htm //www.koonmotors.com/releases/2023/07/230703160008.htm A new study shows the sugar sialic acid, which makes up part of the protective intestinal mucus layer, fuels disease-causing bacteria in the gut. The findings suggest a potential treatment target for intestinal bacterial infections and a range of chronic diseases linked to gut bacteria, including inflammatory bowel disease (IBD), celiac disease, irritable bowel syndrome and short bowel syndrome. Mon, 03 Jul 2023 16:00:08 EDT //www.koonmotors.com/releases/2023/07/230703160008.htm //www.koonmotors.com/releases/2023/06/230621105419.htm Probiotics can help maintain a healthy gut microbiome or restore populations of 'good bacteria' after a heavy course of antibiotics. But now, they could also be used as an effective treatment strategy for certain intestinal diseases, such as Crohn's disease. Researchers have developed a microgel delivery system for probiotics that keeps 'good' bacteria safe while actively clearing out 'bad' ones. In mice, the system treated intestinal inflammation without side effects. Wed, 21 Jun 2023 10:54:19 EDT //www.koonmotors.com/releases/2023/06/230621105419.htm //www.koonmotors.com/releases/2023/06/230608195659.htm 第一次参与commun细胞ication between stress responses in the brain and inflammation in the gastrointestinal (GI) tract have been identified in animal models. Glial cells, which support neurons, communicate stress signals from the central nervous system (CNS) to the semi-autonomous nervous system within the gastrointestinal (GI) tract, called the enteric nervous system (ENS). These psychological stress signals can cause inflammation and exacerbate symptoms of inflammatory bowel disease (IBD). Thu, 08 Jun 2023 19:56:59 EDT //www.koonmotors.com/releases/2023/06/230608195659.htm //www.koonmotors.com/releases/2023/04/230420080703.htm Investigators have identified a genetic variant that increases people's risk of developing perianal Crohn's disease, the most debilitating manifestation of Crohn's disease. The variant generates changes to DNA that lead to a loss of protein function, which in turn, alters how the body recognizes and handles bacteria, making it less effective at fighting infections. Thu, 20 Apr 2023 08:07:03 EDT //www.koonmotors.com/releases/2023/04/230420080703.htm //www.koonmotors.com/releases/2023/04/230407133533.htm A new study could help improve personalized medicine approaches in inflammatory bowel disease by understanding how patients with variants in the PTPN2 gene develop IBD. Fri, 07 Apr 2023 13:35:33 EDT //www.koonmotors.com/releases/2023/04/230407133533.htm //www.koonmotors.com/releases/2023/04/230404114152.htm Fresh insights into how our bodies interact with the microbes living in our guts suggest that a two-drug combination may offer a new way to treat inflammatory bowel diseases such as Crohn's disease and ulcerative colitis. Tue, 04 Apr 2023 11:41:52 EDT //www.koonmotors.com/releases/2023/04/230404114152.htm //www.koonmotors.com/releases/2023/03/230331144510.htm Researchers have succeeded in developing an E. coli-based 'smart microbe' that secretes therapeutic payloads, including antibodies, into the gut. The genetically modified beneficial strain of bacteria blocks intestinal inflammation in a preclinical model of inflammatory bowel disease and has the potential to treat intestinal-based diseases. Fri, 31 Mar 2023 14:45:10 EDT //www.koonmotors.com/releases/2023/03/230331144510.htm //www.koonmotors.com/releases/2023/02/230228113739.htm Inflammatory diseases like rheumatoid arthritis have complex disease mechanisms that can differ from patient to patient with the same diagnosis. This means that currently available drugs have little effect on many patients. Using so-called digital twins, researchers have now obtained a deeper understanding of the 'off and on' proteins that control these diseases. Tue, 28 Feb 2023 11:37:39 EST //www.koonmotors.com/releases/2023/02/230228113739.htm //www.koonmotors.com/releases/2023/02/230223181810.htm Psyllium fiber protects against ulcerative colitis and suppresses inflammation by activating the bile acid nuclear receptor, a mechanism that was previously unrecognized, according to a new study. Thu, 23 Feb 2023 18:18:10 EST //www.koonmotors.com/releases/2023/02/230223181810.htm //www.koonmotors.com/releases/2022/12/221212180540.htm A new drug acts like a master reset switch in the intestines. The compound, called FexD, has previously been found to lower cholesterol, burn fat, and ward off colorectal cancer in mice. Now, the team reports that FexD can also prevent and reverse intestinal inflammation in mouse models of inflammatory bowel disease. Mon, 12 Dec 2022 18:05:40 EST //www.koonmotors.com/releases/2022/12/221212180540.htm //www.koonmotors.com/releases/2022/12/221208114741.htm Commonly used drugs that reduce joint inflammation in patients with rheumatoid arthritis also reduce vascular inflammation and cardiovascular risk, finds a new study. Thu, 08 Dec 2022 11:47:41 EST //www.koonmotors.com/releases/2022/12/221208114741.htm //www.koonmotors.com/releases/2022/12/221202112523.htm B cells are critical to the proper functioning of the immune system. However, researchers have shown that they can sometimes do more harm than good, as their numbers greatly increase after bowel damage, preventing the tissue from healing. The results can be of significance to the treatment of inflammatory bowel disease. Fri, 02 Dec 2022 11:25:23 EST //www.koonmotors.com/releases/2022/12/221202112523.htm //www.koonmotors.com/releases/2022/12/221201123138.htm Changes in a single gene open the door for harmful gut bacteria to set off the inflammation that drives Crohn's disease, according to a new study. These findings could one day help doctors better select targeted treatments for patients with this immune disorder. This particular host gene, called AGR2, encodes part of the cell's machinery that helps prepare new proteins properly so that they can help repel 'bad' bacteria. When anything from microbes to inflammatory conditions disrupts this process, protein production gets backed up, stressing the cell. Extremes in the expression of AGR2 -- when it becomes too active or just silent -- are associated with such stress and the cell's response to it, and formed the basis of the study described Nov. 15 in Cell Reports. Thu, 01 Dec 2022 12:31:38 EST //www.koonmotors.com/releases/2022/12/221201123138.htm //www.koonmotors.com/releases/2022/11/221107103207.htm Inflammatory bowel disease is a risk factor for giving birth preterm even when in apparent disease remission, a new study shows. If corroborated, the results may eventually affect recommendations for women with ulcerative colitis who tries to conceive. Mon, 07 Nov 2022 10:32:07 EST //www.koonmotors.com/releases/2022/11/221107103207.htm //www.koonmotors.com/releases/2022/11/221101124238.htm Bacteria in the small intestine adapt dynamically to our nutritional state, with individual species disappearing and reappearing. Researchers have now been able to comprehensively study the bacteria of the small intestine and their unique adaptability for the first time. The findings contribute to a better understanding of intestinal diseases such as Crohn's disease or Celiac disease and to the development of new therapeutic approaches. Tue, 01 Nov 2022 12:42:38 EDT //www.koonmotors.com/releases/2022/11/221101124238.htm //www.koonmotors.com/releases/2022/09/220908100052.htm Scientists have identified a protein known as sulfatase-2 that plays a critical role in the damage caused by rheumatoid arthritis. The researchers' discovery sheds new light on the molecular processes that drive inflammation seen in rheumatoid arthritis. It could also someday lead to improved treatment of the disease, which currently has no cure. Thu, 08 Sep 2022 10:00:52 EDT //www.koonmotors.com/releases/2022/09/220908100052.htm //www.koonmotors.com/releases/2022/08/220829112839.htm An international consortium of researchers has identified genetic variants in 10 genes that elevate a person's susceptibility to Crohn's disease, a form of inflammatory bowel disease. The findings highlight the causal role of mesenchymal cells in intestinal inflammation, helping to zero in on the genetic roots of inflammatory bowel disease. Mon, 29 Aug 2022 11:28:39 EDT //www.koonmotors.com/releases/2022/08/220829112839.htm //www.koonmotors.com/releases/2022/08/220825094915.htm Immunologists have identified an important intermediate step in innate immune defense. Thu, 25 Aug 2022 09:49:15 EDT //www.koonmotors.com/releases/2022/08/220825094915.htm //www.koonmotors.com/releases/2022/08/220822145145.htm Mutations within Speckled Protein 140 (SP140) are associated with an increased risk of certain immune diseases, including Crohn’s disease. New research provides insights into the mechanisms behind this link, pointing to potential therapeutic targets. Mon, 22 Aug 2022 14:51:45 EDT //www.koonmotors.com/releases/2022/08/220822145145.htm //www.koonmotors.com/releases/2022/08/220817143933.htm 研究人员已经开发出一种方法来帮助一致格fy which human gut microbes are most likely to contribute to a slew of inflammatory diseases like obesity, liver disease, inflammatory bowel disease, cancer and some neurological diseases. Wed, 17 Aug 2022 14:39:33 EDT //www.koonmotors.com/releases/2022/08/220817143933.htm //www.koonmotors.com/releases/2022/08/220817114232.htm Researchers report on the effects of a common herbal remedy on inflammatory bowel disease. A new study shows that DKT -- an herbal medicine containing ginger, pepper, ginseng, and maltose -- reduced the severity of colitis in lab mice by preventing the loss of important gut bacteria and by increasing levels of immune cells in the colon that fight inflammation. Wed, 17 Aug 2022 11:42:32 EDT //www.koonmotors.com/releases/2022/08/220817114232.htm //www.koonmotors.com/releases/2022/08/220803112620.htm Pregnant women with inflammatory bowel disease (IBD) and their babies face increased risks and complications compared to pregnant women without IBD. Those are the findings from a new study that examined outcomes of more than 8 million pregnancies. Wed, 03 Aug 2022 11:26:20 EDT //www.koonmotors.com/releases/2022/08/220803112620.htm //www.koonmotors.com/releases/2022/08/220802121735.htm Colorectal tumors are a common adverse effect of chronic inflammation of the intestine. In a new study, researchers demonstrate that mice models with dendritic cell immunoreceptor (DCIR) protein deficiency are resistant to colonic tumors induced by dextran sodium sulfate and azoxymethane. Further, they identify an antibody that reduces colitis severity and colonic tumor growth, highlighting the potential of DCIR as a therapeutic target. Tue, 02 Aug 2022 12:17:35 EDT //www.koonmotors.com/releases/2022/08/220802121735.htm //www.koonmotors.com/releases/2022/07/220725105652.htm Researchers designed a silicon-based agent that successfully generated hydrogen continuously in the mouse gastrointestinal tract in an ulcerative colitis (UC) model. The hydrogen served as an antioxidant that could eliminate the reactive oxygen species shown to induce the chronic inflammation responsible for the damage and symptoms caused by UC. Mice given the agent had reduced hemorrhage, inflammation, and hyperexcitability in the brain area associated with visceral pain and discomfort. These results may help with the development of a novel treatment for UC. Mon, 25 Jul 2022 10:56:52 EDT //www.koonmotors.com/releases/2022/07/220725105652.htm //www.koonmotors.com/releases/2022/06/220629121148.htm A new oral treatment for ulcerative colitis that focuses on reducing inflammation in gut microbiota has been developed by researchers. Wed, 29 Jun 2022 12:11:48 EDT //www.koonmotors.com/releases/2022/06/220629121148.htm //www.koonmotors.com/releases/2022/06/220608184422.htm People with certain inflammatory immune conditions affecting the joints, bowel and skin, such as rheumatoid arthritis, may have been more at risk of dying or needing hospital care if they got COVID-19 before vaccination compared with the general population, according to a new study. Wed, 08 Jun 2022 18:44:22 EDT //www.koonmotors.com/releases/2022/06/220608184422.htm //www.koonmotors.com/releases/2022/05/220526125750.htm Getting the COVID-19 vaccination strengthened one type of immune response to the SARS-CoV-2 virus in inflammatory bowel disease (IBD) patients even though they were taking immunosuppressant medication, according to researchers. Thu, 26 May 2022 12:57:50 EDT //www.koonmotors.com/releases/2022/05/220526125750.htm //www.koonmotors.com/releases/2022/05/220524124541.htm Young children who grow up with a dog or in a large family may have some protection later in life from a common inflammatory bowel disease known as Crohn's disease, according to a new study. Tue, 24 May 2022 12:45:41 EDT //www.koonmotors.com/releases/2022/05/220524124541.htm //www.koonmotors.com/releases/2022/05/220510122434.htm Using an artificial intelligence (AI) tool that emulates how humans visualize and is trained to recognize and classify images, investigators constructed a model that predicts the postoperative recurrence of Crohn disease with high accuracy by evaluating histological images. The AI tool also revealed previously unrecognized differences in adipose cells and significant differences in the extent of mast cell infiltration in the subserosa, or outer lining of the intestine, comparing patients with and without disease recurrence. Tue, 10 May 2022 12:24:34 EDT //www.koonmotors.com/releases/2022/05/220510122434.htm //www.koonmotors.com/releases/2022/04/220427115747.htm 多年研究大肠杆菌肠道bact的角色eria in Crohn's disease finds that intestinal inflammation liberates chemicals that nourish the bacteria's growth and promotes their ability to cause inflammation. Wed, 27 Apr 2022 11:57:47 EDT //www.koonmotors.com/releases/2022/04/220427115747.htm //www.koonmotors.com/releases/2022/04/220415163754.htm A research group has analyzed how certain immune cells known as innate lymphoid cells (ILCs) develop into mature cells that play a part in inflammatory bowel disease (IBD). The findings could pave the way for more effective treatments against IBD, a disease that causes considerable suffering and that is linked to an increased risk of colorectal cancer. Fri, 15 Apr 2022 16:37:54 EDT //www.koonmotors.com/releases/2022/04/220415163754.htm //www.koonmotors.com/releases/2022/04/220408142953.htm The findings suggest that patients with inflammatory bowel might benefit from therapies that replace disease-driving intestinal viruses with health-promoting viruses. Fri, 08 Apr 2022 14:29:53 EDT //www.koonmotors.com/releases/2022/04/220408142953.htm //www.koonmotors.com/releases/2022/03/220316120813.htm Bile acids, well known for their role in dissolving fats and vitamins, are also important players in gut immunity and inflammation because they regulate the activity of key immune cells linked to a range of inflammatory bowel conditions, such as ulcerative colitis and Crohn's disease, according to new research. Wed, 16 Mar 2022 12:08:13 EDT //www.koonmotors.com/releases/2022/03/220316120813.htm //www.koonmotors.com/releases/2022/02/220207155653.htm An international team has discovered novel properties of the protein Gasdermin B that promotes repair of cells lining the gastrointestinal tract in people with chronic inflammatory disorders like Crohn's disease and ulcerative colitis. Mon, 07 Feb 2022 15:56:53 EST //www.koonmotors.com/releases/2022/02/220207155653.htm //www.koonmotors.com/releases/2022/01/220131153243.htm Researchers have identified a mechanism that underlies inflammation and pain in the colon, and demonstrated that blocking a key receptor from entering colon cells can inhibit inflammation and pain, uncovering a potential target for treating pain in inflammatory bowel disease. Mon, 31 Jan 2022 15:32:43 EST //www.koonmotors.com/releases/2022/01/220131153243.htm //www.koonmotors.com/releases/2022/01/220131132806.htm A growth factor protein produced by rare immune cells in the intestine can protect against the effects of inflammatory bowel disease (IBD), according to a new discovery. Mon, 31 Jan 2022 13:28:06 EST //www.koonmotors.com/releases/2022/01/220131132806.htm //www.koonmotors.com/releases/2022/01/220110145252.htm Results of a new study represent a step toward improving our understanding of Crohn's disease and the factors that cause its intestinal inflammation. Mon, 10 Jan 2022 14:52:52 EST //www.koonmotors.com/releases/2022/01/220110145252.htm //www.koonmotors.com/releases/2022/01/220110103250.htm Increasingly, research links triclosan, an antimicrobial found in thousands of consumer products, with the gut microbiome and gut inflammation. A new study looks at the potential for combating damage to the intestine. The findings suggest new approaches for improving the diagnosis, prevention and treatment of inflammatory bowel disease. Mon, 10 Jan 2022 10:32:50 EST //www.koonmotors.com/releases/2022/01/220110103250.htm //www.koonmotors.com/releases/2021/12/211222084024.htm Microplastics -- tiny pieces of plastic less than 5 mm in length -- are everywhere, from bottled water to food to air. According to recent estimates, people consume tens of thousands of these particles each year, with unknown health consequences. Now, researchers have found that people with inflammatory bowel disease (IBD) have more microplastics in their feces than healthy controls, suggesting that the fragments could be related to the disease process. Wed, 22 Dec 2021 08:40:24 EST //www.koonmotors.com/releases/2021/12/211222084024.htm //www.koonmotors.com/releases/2021/12/211216145847.htm Researchers have shown that blocking IL-6 and TNF cytokines provides a more effective approach to preventing life-threatening graft-versus-host-disease, an inflammatory condition that develops in patients after their allogeneic hematopoietic stem cell transplantation. Thu, 16 Dec 2021 14:58:47 EST //www.koonmotors.com/releases/2021/12/211216145847.htm //www.koonmotors.com/releases/2021/11/211119155504.htm People taking TNF inhibitors, a kind of immunosuppressive drug used to treat rheumatoid arthritis and other autoimmune conditions, produced a weaker and shorter-lived antibody response after two doses of Pfizer's COVID-19 vaccine, according to a new study. A third vaccine dose drove antibody levels back up, indicating that this additional dose may provide protection as the virus's delta variant continues to spread. Fri, 19 Nov 2021 15:55:04 EST //www.koonmotors.com/releases/2021/11/211119155504.htm //www.koonmotors.com/releases/2021/11/211118203520.htm An active metabolite of vitamin D (not the over-the-counter version) is involved in shutting down inflammation, new research shows. Thu, 18 Nov 2021 20:35:20 EST //www.koonmotors.com/releases/2021/11/211118203520.htm //www.koonmotors.com/releases/2021/11/211118061550.htm Researchers using mouse models found that stress hormones suppressed the innate immune system that normally protects the gut from invasive Enterobacteriaceae, a group of bacteria including E. coli which has been linked to Crohn's disease. Thu, 18 Nov 2021 06:15:50 EST //www.koonmotors.com/releases/2021/11/211118061550.htm //www.koonmotors.com/releases/2021/11/211105150307.htm New data shows how inflammatory reactions can be resolved by changes to the metabolism of macrophages. Danger signals released by damaged cells during inflammation play a role during this process. 'Rewiring' the mitochondria in the macrophages protects them against overloading and can thus improve the way in which parts of damaged cells are eliminated and resolve the inflammatory reaction. Fri, 05 Nov 2021 15:03:07 EDT //www.koonmotors.com/releases/2021/11/211105150307.htm //www.koonmotors.com/releases/2021/11/211103082557.htm Inflammatory cytokines are molecules that are secreted by immune cells to promote inflammation. A study found that measuring inflammatory cytokines may help predict patient outcomes after traumatic injury, which is the leading cause of mortality in individuals under 50 years of age. Wed, 03 Nov 2021 08:25:57 EDT //www.koonmotors.com/releases/2021/11/211103082557.htm //www.koonmotors.com/releases/2021/10/211026124318.htm An international team of scientists has identified a new connection between certain molecules produced by the microbiome and the function of a protein that impacts gut inflammation. Tue, 26 Oct 2021 12:43:18 EDT //www.koonmotors.com/releases/2021/10/211026124318.htm //www.koonmotors.com/releases/2021/10/211020135907.htm Researchers have uncovered a fundamental role of glial cells in the nervous system of the gut in maintaining a healthy intestine. These cells have been found to coordinate the immune responses of the gut following pathogen invasion and could be key targets when exploring new treatments for inflammatory bowel conditions. Wed, 20 Oct 2021 13:59:07 EDT //www.koonmotors.com/releases/2021/10/211020135907.htm //www.koonmotors.com/releases/2021/10/211006134936.htm Scientists hope that tiny sacs of material excreted by cells -- so-called extracellular vesicles -- can be used to deliver drugs inside the body. Researchers now show that these nano-bubbles can transport protein drugs that reduce inflammation caused by different diseases. The technique shows promising results in animal models. Wed, 06 Oct 2021 13:49:36 EDT //www.koonmotors.com/releases/2021/10/211006134936.htm //www.koonmotors.com/releases/2021/10/211004104215.htm New research has revealed a direct link between fatty tissue and Crohn's disease. Mon, 04 Oct 2021 10:42:15 EDT //www.koonmotors.com/releases/2021/10/211004104215.htm //www.koonmotors.com/releases/2021/07/210729111901.htm Researchers have discovered the underlying genetic cause of a rare childhood disorder that mimics inflammatory bowel disease, a finding that may help researchers uncover the roots of a host of other inflammatory and autoimmune disorders. Thu, 29 Jul 2021 11:19:01 EDT //www.koonmotors.com/releases/2021/07/210729111901.htm //www.koonmotors.com/releases/2021/07/210720114314.htm Researchers have found that immunoglobulin A (IgA) deficiency leads to disruption of the ileal gut microbiota and increased inflammation in the ileum in mice. This suggests that IgA plays an important role in mucosal homeostasis by regulating the intestinal microbiota and protecting against mucosal inflammation, especially in the ileum Tue, 20 Jul 2021 11:43:14 EDT //www.koonmotors.com/releases/2021/07/210720114314.htm //www.koonmotors.com/releases/2021/07/210714183430.htm A higher intake of ultra-processed food is associated with higher risk of inflammatory bowel disease (IBD), finds a new study. Wed, 14 Jul 2021 18:34:30 EDT //www.koonmotors.com/releases/2021/07/210714183430.htm //www.koonmotors.com/releases/2021/07/210709193616.htm Growth impairment, a common complication of Crohn's disease in children, occurs more often in males than females, but the reasons are unclear. Now, a physician-scientists have found that factors associated with statural growth differ by sex. Fri, 09 Jul 2021 19:36:16 EDT //www.koonmotors.com/releases/2021/07/210709193616.htm //www.koonmotors.com/releases/2021/06/210629120442.htm The groundbreaking technology may revolutionize the treatment of cancer and a wide range of diseases and medical conditions. Tue, 29 Jun 2021 12:04:42 EDT //www.koonmotors.com/releases/2021/06/210629120442.htm //www.koonmotors.com/releases/2021/06/210609105835.htm Patients with inflammatory bowel diseases (IBD) do not appear to have increased risk of side effects from the Pfizer or Moderna COVID-19 vaccines, according to a recent study. In fact, those being treated with advanced immune-modifying therapies may experience them less often than the general population. Wed, 09 Jun 2021 10:58:35 EDT //www.koonmotors.com/releases/2021/06/210609105835.htm //www.koonmotors.com/releases/2021/05/210528114008.htm A new study shows how a novel consortium of bacteria that live in the digestive tracts of healthy individuals can be used to prevent and treat aggressive colitis in humanized mouse models. Fri, 28 May 2021 11:40:08 EDT //www.koonmotors.com/releases/2021/05/210528114008.htm //www.koonmotors.com/releases/2021/05/210527112557.htm Crohn's disease, a type of inflammatory bowel disease (IBD) that causes inflammation (pain and swelling) in the gastrointestinal tract, can cause daily health problems, frequent hospitalizations and surgery when not adequately controlled. While there is no cure for Crohn's disease, there are treatments that can help patients live a symptom-free life. Thu, 27 May 2021 11:25:57 EDT //www.koonmotors.com/releases/2021/05/210527112557.htm