//www.koonmotors.com/news/health_medicine/bladder_disorders/ Overactive bladder, urinary incontinence, cystitis and other bladder disorders. en-us Wed, 06 Sep 2023 14:45:12 EDT Wed, 06 Sep 2023 14:45:12 EDT 60 //www.koonmotors.com/images/scidaily-logo-rss.png//www.koonmotors.com/news/health_medicine/bladder_disorders/ For more science news, visit ScienceDaily. //www.koonmotors.com/releases/2023/06/230621121032.htm As men age, some of their cells lose the very thing that makes them biological males -- the Y chromosome -- and this loss hampers the body's ability to fight cancer, according to new research. The study found that loss of the Y chromosome helps cancer cells evade the body's immune system. This common impact of the aging process in men results in aggressive bladder cancer, but somehow also renders the disease more vulnerable -- and responsive -- to a standard treatment called immune checkpoint inhibitors. Wed, 21 Jun 2023 12:10:32 EDT //www.koonmotors.com/releases/2023/06/230621121032.htm //www.koonmotors.com/releases/2023/05/230524181939.htm Engineers have designed a new class of 'microrobots' several times smaller than the width of a human hair that may be able to treat human illnesses like interstitial cystitis -- a painful bladder disease that affects millions of Americans. Wed, 24 May 2023 18:19:39 EDT //www.koonmotors.com/releases/2023/05/230524181939.htm //www.koonmotors.com/releases/2023/04/230420080722.htm Drinking cranberry juice has long been a mythical prevention strategy for women who develop a urinary tract infection -- and new medical evidence shows consuming cranberry products is an effective way to prevent a UTI before it gets started. A global study looking at the benefits of cranberry products has determined cranberry juice, and its supplements, reduce the risk of repeat symptomatic UTIs in women by more than a quarter, in children by more than half, and in people susceptible to UTI following medical interventions by about 53%. Thu, 20 Apr 2023 08:07:22 EDT //www.koonmotors.com/releases/2023/04/230420080722.htm //www.koonmotors.com/releases/2023/03/230309071145.htm Researchers have developed an ultra-soft and highly stretchable tissue-adhesive hydrogel-based multifunctional implantable sensor for monitoring of overactive bladder. Thu, 09 Mar 2023 07:11:45 EST //www.koonmotors.com/releases/2023/03/230309071145.htm //www.koonmotors.com/releases/2023/01/230111150802.htm 投机取巧的细菌不动杆菌baumannii rarely sickens healthy people but causes serious infections in hospitalized patients. A study in mice suggests that Acinetobacter can hide undetected in bladder cells and then reactivate when stimulated by medical intervention. The findings suggest that patients may bring Acinetobacter into hospitals and that screening patients could supplement current infection-control efforts. Wed, 11 Jan 2023 15:08:02 EST //www.koonmotors.com/releases/2023/01/230111150802.htm //www.koonmotors.com/releases/2022/12/221228130358.htm An enzyme that defends human cells against viruses can help drive cancer evolution towards greater malignancy by causing myriad mutations in cancer cells, according to a new study. The finding suggests that the enzyme may be a potential target for future cancer treatments. Wed, 28 Dec 2022 13:03:58 EST //www.koonmotors.com/releases/2022/12/221228130358.htm //www.koonmotors.com/releases/2022/10/221007190634.htm A new technique which combines the use of two ultrasound technologies may offer an option to move kidney stones out of the ureter with minimal pain and no anesthesia, according to a new feasibility study. Fri, 07 Oct 2022 19:06:34 EDT //www.koonmotors.com/releases/2022/10/221007190634.htm //www.koonmotors.com/releases/2022/10/221005141743.htm An epigenetics drug currently being used for the treatment of blood cancers and rare sarcomas can stop the growth of bladder cancer by activating the immune system, reports a new study in mice. The drug is now being tested in a national clinical trial for patients with late-stage bladder cancer. Wed, 05 Oct 2022 14:17:43 EDT //www.koonmotors.com/releases/2022/10/221005141743.htm //www.koonmotors.com/releases/2022/09/220920100739.htm Lower immunity and recurring infections are common in type 1 and type 2 diabetes. Researchers now show that the immune system of people with diabetes has lower levels of the antimicrobial peptide psoriasin, which compromises the urinary bladder's cell barrier, increasing the risk of urinary tract infection. Tue, 20 Sep 2022 10:07:39 EDT //www.koonmotors.com/releases/2022/09/220920100739.htm //www.koonmotors.com/releases/2022/09/220912112430.htm Researchers have made two important discoveries about the mechanism by which bladder cancer cells foil attacks from the immune system. The research could lead to a new therapeutic option for patients with these types of tumors. Mon, 12 Sep 2022 11:24:30 EDT //www.koonmotors.com/releases/2022/09/220912112430.htm //www.koonmotors.com/releases/2022/08/220822174822.htm Many bladder cancer patients cannot tolerate the strong side effects of the gold standard treatment. Researchers have found a way to minimize those side effects and are poised to move into clinical trials. Mon, 22 Aug 2022 17:48:22 EDT //www.koonmotors.com/releases/2022/08/220822174822.htm //www.koonmotors.com/releases/2022/08/220804130616.htm Investigators have identified genetic signatures that could predict whether tumors in patients with bladder and other cancers will respond to immunotherapy. Thu, 04 Aug 2022 13:06:16 EDT //www.koonmotors.com/releases/2022/08/220804130616.htm //www.koonmotors.com/releases/2022/07/220712102724.htm Development of a precision medicine technology based on artificial intelligence that predicts immunotherapy response in cancer patients. Tue, 12 Jul 2022 10:27:24 EDT //www.koonmotors.com/releases/2022/07/220712102724.htm //www.koonmotors.com/releases/2022/06/220628083255.htm Urinary tract infections are both very common and potentially very dangerous. Around 80 per cent of UTIs are caused by uropathogenic E. coli (UPEC), which is increasingly resistant to antibiotics. E. coli-related death due to antimicrobial resistance is the leading cause of bacterial fatalities worldwide. New research examining bacterial behavior over the infection cycle is an important step towards enabling new treatments or prevention in the future. Tue, 28 Jun 2022 08:32:55 EDT //www.koonmotors.com/releases/2022/06/220628083255.htm //www.koonmotors.com/releases/2022/06/220609195008.htm Male sex hormones interfere with the body's ability to fight bladder cancer, likely explaining why males experience higher cancer rates and more deadly disease, according to a new study. Thu, 09 Jun 2022 19:50:08 EDT //www.koonmotors.com/releases/2022/06/220609195008.htm //www.koonmotors.com/releases/2022/05/220515113215.htm Robot-assisted surgery used to perform bladder cancer removal and reconstruction enables patients to recover far more quickly and spend significantly (20 per cent) less time in hospital, concludes a new clinical trial. Sun, 15 May 2022 11:32:15 EDT //www.koonmotors.com/releases/2022/05/220515113215.htm //www.koonmotors.com/releases/2022/05/220509171056.htm Researchers describe a novel form of gene regulation that is altered in bladder cancer, leading to the boosting of a gene pathway that helps the cancer cells survive during rapid growth. The work focuses on a 22-base fragment of transfer RNA, tRF-3b, which is modified by the enzyme complex TRMT6/61A. In bladder cancer, the levels of TRMT6/61A -- a methyltransferase -- are elevated. The methylation modification prevents tRF-3bs from silencing the expression of various genes in the unfolded protein response pathway in the cancer cells. Mon, 09 May 2022 17:10:56 EDT //www.koonmotors.com/releases/2022/05/220509171056.htm //www.koonmotors.com/releases/2022/05/220505180921.htm A study suggests that women who get recurrent urinary tract infections (UTIs) may be caught in a vicious cycle in which antibiotics given to eradicate one infection predispose them to develop another. Thu, 05 May 2022 18:09:21 EDT //www.koonmotors.com/releases/2022/05/220505180921.htm //www.koonmotors.com/releases/2022/04/220422094310.htm In a small but multi-institutional study, an artificial intelligence-based system improved providers' assessments of whether patients with bladder cancer had complete response to chemotherapy before a radical cystectomy (bladder removal surgery). Fri, 22 Apr 2022 09:43:10 EDT //www.koonmotors.com/releases/2022/04/220422094310.htm //www.koonmotors.com/releases/2022/03/220328090017.htm Adding an anti-inflammatory medication to immunotherapy and standard chemotherapy drugs may provide long-term suppression of aggressive bladder tumor growth, according to a proof-of-concept study. Mon, 28 Mar 2022 09:00:17 EDT //www.koonmotors.com/releases/2022/03/220328090017.htm //www.koonmotors.com/releases/2022/03/220309104406.htm Women with overactive bladder are frequently frustrated with treatment, which leads to discontinuation of therapy. Asynchronous telehealth visits keep women engaged in follow-up care, accelerates trials of different medications and reinforces behavioral changes. The women in this pilot study reported improvement in symptoms and high satisfaction with asynchronous visits. Wed, 09 Mar 2022 10:44:06 EST //www.koonmotors.com/releases/2022/03/220309104406.htm //www.koonmotors.com/releases/2022/01/220106152438.htm A study evaluating the risk of overactive bladder as a side effect of cholinesterase inhibitor drugs taken for dementia and Alzheimer's disease, finds that one drug -- Donepezil -- is linked to increased risk of the distressing side effect. Thu, 06 Jan 2022 15:24:38 EST //www.koonmotors.com/releases/2022/01/220106152438.htm //www.koonmotors.com/releases/2021/12/211215082038.htm If you're feeling more sudden urges to run to the bathroom as you age, you're not alone. A new study suggests postmenopausal women aged 45 to 54 years are more likely to have overactive bladder (OAB) syndrome. Additionally, obesity and multiple births put a woman at greater risk for stress urinary incontinence (SUI). Wed, 15 Dec 2021 08:20:38 EST //www.koonmotors.com/releases/2021/12/211215082038.htm //www.koonmotors.com/releases/2021/11/211108130842.htm In just a few weeks a completely new organism develops from a fertilized egg cell. The real miracle is that a bunch of identical stem cells turns into completely different, specialized cell types. A team has now been able to show that the specialization of individual cells during embryonic development is not, as previously assumed, exclusively left to chance but is rather determined by cell communication. Mon, 08 Nov 2021 13:08:42 EST //www.koonmotors.com/releases/2021/11/211108130842.htm //www.koonmotors.com/releases/2021/10/211019120103.htm 在你确定动态事件发生inary tract infections (UTI) has revealed a new potential strategy to combat this condition, considered the most common type of infection. Tue, 19 Oct 2021 12:01:03 EDT //www.koonmotors.com/releases/2021/10/211019120103.htm //www.koonmotors.com/releases/2021/10/211014102027.htm A new report finds more than 46,000 cancer cases annually in the United States could be prevented if Americans met the 5 hours per week of moderate-intensity recommended physical activity guidelines. Thu, 14 Oct 2021 10:20:27 EDT //www.koonmotors.com/releases/2021/10/211014102027.htm //www.koonmotors.com/releases/2021/10/211001130256.htm More than half of U.S. women will experience at least one urinary tract infection (UTI) in their lifetimes, while a quarter will have a subsequent infection. Recurrent urinary tract infections are defined as two or more infections in six months or three or more in a year. Fri, 01 Oct 2021 13:02:56 EDT //www.koonmotors.com/releases/2021/10/211001130256.htm //www.koonmotors.com/releases/2021/09/210901100326.htm Two recent studies describe the potential of liquid biopsies to identify and track tumor growth in two very different cancers: bladder cancer and peripheral nerve tumors. Despite the differences between these cancers and their associated biopsies, the studies demonstrate the possible benefits of this relatively new tool in the fight against cancer. Wed, 01 Sep 2021 10:03:26 EDT //www.koonmotors.com/releases/2021/09/210901100326.htm //www.koonmotors.com/releases/2021/08/210802140135.htm Scientists have developed two complementary bladder models to study urinary tract infections (UTIs) caused by E. coli: bladder organoids and a bladder-on-a- chip. The two studies reveal how bacteria invade the bladder, and how they evade the immune system and resist antibiotics. The studies they provide researchers and clinicians with a powerful new for studying the pathogenesis and treatment of UTIs. Mon, 02 Aug 2021 14:01:35 EDT //www.koonmotors.com/releases/2021/08/210802140135.htm //www.koonmotors.com/releases/2021/07/210722194950.htm Researchers report a study has demonstrated that patients with advanced bladder cancers whose tumors have a mutated FGFR3 gene respond to immunotherapy in a manner that is similar to patients without that mutation. This discovery runs counter to previous research that suggested FGFR3-mutated bladder cancers should not be treated with immunotherapy. Thu, 22 Jul 2021 19:49:50 EDT //www.koonmotors.com/releases/2021/07/210722194950.htm //www.koonmotors.com/releases/2021/07/210715090826.htm A small regulatory RNA found in many problematic bacteria, including Escherichia coli, appears to be responsible for managing the response of these bacteria to environmental stresses. Researchers see a promising avenue for more effective treatment of antibiotic-resistant bacteria. Thu, 15 Jul 2021 09:08:26 EDT //www.koonmotors.com/releases/2021/07/210715090826.htm //www.koonmotors.com/releases/2021/06/210621123721.htm A blood test that can detect tiny amounts of circulating cancer DNA may be able to identify risk of cancer recurrence and guide precision treatment in bladder cancer following surgery, according to a clinical study. Mon, 21 Jun 2021 12:37:21 EDT //www.koonmotors.com/releases/2021/06/210621123721.htm //www.koonmotors.com/releases/2021/03/210301151532.htm Researchers describe a new vaccination strategy that they think could re-program the body to fight off the bacteria that cause urinary tract infections. Mon, 01 Mar 2021 15:15:32 EST //www.koonmotors.com/releases/2021/03/210301151532.htm //www.koonmotors.com/releases/2021/02/210225143648.htm A DNA-damaging bacterial toxin called colibactin is produced in patients with urinary tract infections (UTIs), according to a new study. Thu, 25 Feb 2021 14:36:48 EST //www.koonmotors.com/releases/2021/02/210225143648.htm //www.koonmotors.com/releases/2020/11/201111153104.htm An implantable smart wrap that fits safely and securely around the bladder may one day help people who have under-active bladders, a condition that hinders patients from urinating regularly and comfortably, according to an international team of researchers. Wed, 11 Nov 2020 15:31:04 EST //www.koonmotors.com/releases/2020/11/201111153104.htm //www.koonmotors.com/releases/2020/10/201014140958.htm Scientists have found that the main sensor protein enabling our sense of touch also underlies the feeling of having a full bladder and makes normal bladder function possible. The discovery marks a key advance in basic neurobiology and may also lead to better treatments for bladder control and urination problems, which are common especially among the elderly. Wed, 14 Oct 2020 14:09:58 EDT //www.koonmotors.com/releases/2020/10/201014140958.htm //www.koonmotors.com/releases/2020/07/200702113731.htm Using state-of-the-art approaches coupled with bio- and cheminformatics and machine learning, researchers have succeeded in discovering new, bioactive components of the Baltic Sea Baltic Sea seaweed Fucus vesiculosus and its fungal symbiont against infectious bacteria or skin cancer. Thu, 02 Jul 2020 11:37:31 EDT //www.koonmotors.com/releases/2020/07/200702113731.htm //www.koonmotors.com/releases/2020/05/200505105333.htm 研究人员已经开发出一种新的设备,可以monitor bladder volume in real-time and effectively empty the bladder. Tue, 05 May 2020 10:53:33 EDT //www.koonmotors.com/releases/2020/05/200505105333.htm //www.koonmotors.com/releases/2020/04/200428225426.htm Researchers have recreated how toxins from smoking cause unique patterns of DNA damage. The discovery could help scientists better understand the cause of bladder cancer and the link to smoking. The causes of bladder cancer remain largely unknown, however smoking is seen as the main risk factor for the disease. Tue, 28 Apr 2020 22:54:26 EDT //www.koonmotors.com/releases/2020/04/200428225426.htm //www.koonmotors.com/releases/2020/04/200416135845.htm Researchers have developed a new method for biomarker discovery of urological cancers. The method enables timely diagnosis and treatment of cancer. Urological cancers include e.g. prostate, bladder and kidney cancers. Thu, 16 Apr 2020 13:58:45 EDT //www.koonmotors.com/releases/2020/04/200416135845.htm //www.koonmotors.com/releases/2020/01/200129131529.htm The fight against Urinary Tract Infection pain, discomfort and a constant urge to urinate has taken a step forward with scientists identifying how the immune systems defence against bladder infection causes nerves to magnify sensations felt by patients. Flinders University researchers at SAHMRI in collaboration with Griffith University on the Gold Coast, have analysed how the immune system responds to urinary tract infections and the direct link this response has to magnifying bladder pain. Wed, 29 Jan 2020 13:15:29 EST //www.koonmotors.com/releases/2020/01/200129131529.htm //www.koonmotors.com/releases/2019/12/191213115401.htm While trying to develop a comparatively easy, inexpensive way to give physicians and their patients with bladder cancer a better idea of likely outcome and best treatment options, scientists found that sophisticated new subtyping techniques designed to do this provide no better information than long-standing pathology tests. Fri, 13 Dec 2019 11:54:01 EST //www.koonmotors.com/releases/2019/12/191213115401.htm //www.koonmotors.com/releases/2019/11/191112095747.htm Researchers have come up with a way to combine the anthrax toxin with a growth factor to kill bladder cancer cells and tumors. Tue, 12 Nov 2019 09:57:47 EST //www.koonmotors.com/releases/2019/11/191112095747.htm //www.koonmotors.com/releases/2019/10/191016124608.htm Hyperbaric oxygen therapy (HBOT) can relieve self-reported symptoms and side-effects of radiotherapy against cancer in the pelvic region, a study shows. After 30-40 sessions in a hyperbaric chamber, many patients experienced reductions in bleeding, urinary incontinence, and pain alike. Wed, 16 Oct 2019 12:46:08 EDT //www.koonmotors.com/releases/2019/10/191016124608.htm //www.koonmotors.com/releases/2019/10/191012141218.htm A drug widely prescribed for a bladder condition for decades, now appears to be toxic to the retina, the light sensing tissue at the back of the eye that allows us to see. Sat, 12 Oct 2019 14:12:18 EDT //www.koonmotors.com/releases/2019/10/191012141218.htm //www.koonmotors.com/releases/2019/08/190821124349.htm Researchers have discovered that an initial UTI can set the tone for subsequent infections. In mouse studies, the researchers found that a transient infection triggers a short-lived inflammatory response that rapidly eliminates the bacteria. But a lingering infection leads to persistent inflammation and long-lasting changes to the bladder that prime the immune system to overreact to bacteria the next time, worsening the infection. Wed, 21 Aug 2019 12:43:49 EDT //www.koonmotors.com/releases/2019/08/190821124349.htm //www.koonmotors.com/releases/2019/08/190813101943.htm Sufferers of recurring urinary tract infections (UTIs) could expect more effective treatments. UTIs are one of the most common bacterial infections. Tue, 13 Aug 2019 10:19:43 EDT //www.koonmotors.com/releases/2019/08/190813101943.htm //www.koonmotors.com/releases/2019/07/190725130817.htm Researchers have devised a very promising non-invasive and individualized technique for detecting and treating bladder cancer. The method uses a 'liquid biopsy' -- a urine specimen -- instead of the invasive tumor sampling needed today, and a method to culture cancer cells that can reveal the molecular underpinnings of each patient's unique bladder cancer. Thu, 25 Jul 2019 13:08:17 EDT //www.koonmotors.com/releases/2019/07/190725130817.htm //www.koonmotors.com/releases/2019/07/190715114308.htm One of the most commonly performed surgeries to treat stress urinary incontinence in women may have better long-term results than another common surgical technique, according to a new study. The retrospective study of more than 1,800 cases at Mayo Clinic from 2002 to 2012 found that the need for additional surgery was twice as high after a transobturator sling surgery compared with a retropubic sling procedure. Mon, 15 Jul 2019 11:43:08 EDT //www.koonmotors.com/releases/2019/07/190715114308.htm //www.koonmotors.com/releases/2019/07/190704191431.htm A strain of the common cold virus has been found to potentially target, infect and destroy cancer cells in patients with bladder cancer, a new study reports. No trace of the cancer was found in one patient following treatment with the virus. Thu, 04 Jul 2019 19:14:31 EDT //www.koonmotors.com/releases/2019/07/190704191431.htm //www.koonmotors.com/releases/2019/05/190513120739.htm A new finding shows that several species of bacteria reside in bladder tissue of postmenopausal women who experience recurrent urinary tract infections (RUTIs). The results represent the first systematic analysis of biopsies from patients in this population. Mon, 13 May 2019 12:07:39 EDT //www.koonmotors.com/releases/2019/05/190513120739.htm //www.koonmotors.com/releases/2019/05/190511083926.htm A new study suggests why urinary tract infections (UTIs) have such a high recurrence rate in postmenopausal women: several species of bacteria can invade the bladder walls. Sat, 11 May 2019 08:39:26 EDT //www.koonmotors.com/releases/2019/05/190511083926.htm //www.koonmotors.com/releases/2019/02/190207132420.htm A therapy derived from the eggs of parasitic worms helps to protect against one of chemotherapy's debilitating side effects by significantly downregulating major proinflammatory pathways, reducing inflammation. Thu, 07 Feb 2019 13:24:20 EST //www.koonmotors.com/releases/2019/02/190207132420.htm //www.koonmotors.com/releases/2018/12/181219093903.htm Research has demonstrated that vaginal childbirth substantially increases the probability a woman will develop a pelvic floor disorder later in life. Wed, 19 Dec 2018 09:39:03 EST //www.koonmotors.com/releases/2018/12/181219093903.htm //www.koonmotors.com/releases/2018/10/181022122843.htm The biological differences between women and men go beyond basic anatomy. Researchers must consider sex differences down to the cellular level in order to discover crucial information about the varied development, function, and biology between women and men. Mon, 22 Oct 2018 12:28:43 EDT //www.koonmotors.com/releases/2018/10/181022122843.htm //www.koonmotors.com/releases/2018/10/181019120736.htm Overactive bladder (OAB) is a common form of urinary incontinence that is widely treated with pelvic floor muscle (PFM) training. A new laboratory study lends insights into how PFM training works: by reducing contractions of the detrusor muscle of the bladder. 星期五,2018年10月19日12:07:36美国东部时间 //www.koonmotors.com/releases/2018/10/181019120736.htm //www.koonmotors.com/releases/2018/10/181003134447.htm Drinking an additional 1.5 liters of water daily can reduce recurring bladder infections in premenopausal women by nearly half, a yearlong study of otherwise healthy women with a history of repeated infections has found. Wed, 03 Oct 2018 13:44:47 EDT //www.koonmotors.com/releases/2018/10/181003134447.htm //www.koonmotors.com/releases/2018/09/180917153701.htm Scientists have shown that cellulose serves a mortar-like role to enhance the adhesion of bacteria to bladder cells, causing urinary tract infections. Mon, 17 Sep 2018 15:37:01 EDT //www.koonmotors.com/releases/2018/09/180917153701.htm //www.koonmotors.com/releases/2018/08/180831110408.htm Patients with muscle-invasive bladder cancer have been shown to benefit from chemotherapy prior to surgical removal of the bladder. But which type of chemotherapy leads to the best outcomes in terms of complete response rates or cancer control? Researchers examined data from more than 800 surgical patients with advanced bladder cancer. Fri, 31 Aug 2018 11:04:08 EDT //www.koonmotors.com/releases/2018/08/180831110408.htm //www.koonmotors.com/releases/2018/08/180829081336.htm This study reveals how some tumors fuel their own growth and how stopping this vicious cycle could lead to new treatments. Wed, 29 Aug 2018 08:13:36 EDT //www.koonmotors.com/releases/2018/08/180829081336.htm