//www.koonmotors.com/news/health_medicine/birth_defects/ Read the latest medical research on birth defects including risk factors, detection and treatment options. en-us Wed, 06 Sep 2023 14:45:25 EDT Wed, 06 Sep 2023 14:45:25 EDT 60 //www.koonmotors.com/images/scidaily-logo-rss.png//www.koonmotors.com/news/health_medicine/birth_defects/ For more science news, visit ScienceDaily. //www.koonmotors.com/releases/2023/09/230901124051.htm In a new study, researchers used mice to understand how DiNP affects pregnancy. Fri, 01 Sep 2023 12:40:51 EDT //www.koonmotors.com/releases/2023/09/230901124051.htm //www.koonmotors.com/releases/2023/08/230830131948.htm When an immunocompromised person's system begins to recover and produce more white blood cells, it's usually a good thing -- unless they develop C-IRIS, a potentially deadly inflammatory condition. New research has found that the pulmonary distress often associated with C-IRIS is caused not by damage to the lungs, but by newly populated T-cells infiltrating the brain. Knowing this mechanism of action can help researchers and physicians better understand the illness and provide new treatment targets. Wed, 30 Aug 2023 13:19:48 EDT //www.koonmotors.com/releases/2023/08/230830131948.htm //www.koonmotors.com/releases/2023/08/230824111854.htm Preterm babies given a supplement with a combination of omega-3 and omega-6 fatty acids have better visual function by the age of two and a half. Thu, 24 Aug 2023 11:18:54 EDT //www.koonmotors.com/releases/2023/08/230824111854.htm //www.koonmotors.com/releases/2023/08/230817163900.htm An international team of scientists has discovered an additional potential cause of the genetic mutations that result in rare neurodegenerative conditions such as Huntington's disease. Thu, 17 Aug 2023 16:39:00 EDT //www.koonmotors.com/releases/2023/08/230817163900.htm //www.koonmotors.com/releases/2023/08/230816160006.htm Researcher discovers possible link of mitochondrial function to the development of schizophrenia. Wed, 16 Aug 2023 16:00:06 EDT //www.koonmotors.com/releases/2023/08/230816160006.htm //www.koonmotors.com/releases/2023/08/230810110412.htm Two distinct neurodevelopmental abnormalities that arise just weeks after the start of brain development have been associated with the emergence of autism spectrum disorder, according to a new study in which researchers developed brain organoids from the stem cells of boys diagnosed with the disorder. Thu, 10 Aug 2023 11:04:12 EDT //www.koonmotors.com/releases/2023/08/230810110412.htm //www.koonmotors.com/releases/2023/08/230804123726.htm 研究表明,产前诊断或诊断接头nosis before a baby is born, is associated with earlier surgery for babies with congenital heart defects, the most common birth defects affecting nearly 1% of all live births. The association was demonstrated for critical defects (when heart surgery is required before the infant leaves the hospital) and certain types of noncritical defects, which constitute about 75% of all congenital heart defects. Fri, 04 Aug 2023 12:37:26 EDT //www.koonmotors.com/releases/2023/08/230804123726.htm //www.koonmotors.com/releases/2023/07/230728170611.htm A new study of cadmium in pregnant women yields crucial insights into the placenta's role in regulating toxin exposure. Fri, 28 Jul 2023 17:06:11 EDT //www.koonmotors.com/releases/2023/07/230728170611.htm //www.koonmotors.com/releases/2023/07/230721113127.htm A new study has shown that hardship experienced by mothers during their own childhood or during pregnancy is reflected in the composition of their 2-year-old children's gut microbiome. It was previously understood that in rodents, prenatal stress affects microbiomes into adulthood, but how long after birth the effects lasted in humans was unknown. The changes to this community of microorganisms are likely among the ways that hardship affects a child's socioemotional development. Fri, 21 Jul 2023 11:31:27 EDT //www.koonmotors.com/releases/2023/07/230721113127.htm //www.koonmotors.com/releases/2023/07/230719150017.htm Combining two types of heart scan techniques could help doctors to detect the deadly heart condition hypertrophic cardiomyopathy (HCM) before symptoms and signs on conventional tests appear. Wed, 19 Jul 2023 15:00:17 EDT //www.koonmotors.com/releases/2023/07/230719150017.htm //www.koonmotors.com/releases/2023/07/230719112601.htm Researchers lead a study showing the cellular detail of how the placenta changes during pregnancy. Wed, 19 Jul 2023 11:26:01 EDT //www.koonmotors.com/releases/2023/07/230719112601.htm //www.koonmotors.com/releases/2023/07/230717175955.htm 一个研究小组公布的新发现emphasize the crucial role of the urinary and genital tract microbiota in adverse pregnancy outcomes and genomic instability that originate in the womb during fetal development. The study established a new link between genomic instability and a protein from Mycoplasma fermentans, a kind of bacterium that commonly colonizes the urogenital tract. This bacterial protein also reduced fertility in mother mice and resulted in more birth defects in their newborn pups. Mon, 17 Jul 2023 17:59:55 EDT //www.koonmotors.com/releases/2023/07/230717175955.htm //www.koonmotors.com/releases/2023/07/230717143210.htm Data scientists have created an artificial intelligence model that may more accurately predict which existing medicines, not currently classified as harmful, may in fact lead to congenital disabilities. The model, or 'knowledge graph,' also has the potential to predict the involvement of pre-clinical compounds that may harm the developing fetus. The study is the first known of its kind to use knowledge graphs to integrate various data types to investigate the causes of congenital disabilities. Mon, 17 Jul 2023 14:32:10 EDT //www.koonmotors.com/releases/2023/07/230717143210.htm //www.koonmotors.com/releases/2023/07/230717115837.htm A recent study centers around the idea that various anti-inflammatory drugs could be effective treatments for Alzheimer's disease. This study focused on a protein known as p38. Many labs have been working with this protein as a potential target for drug development to treat Alzheimer's disease and other conditions with neuroinflammatory dysfunction. Mon, 17 Jul 2023 11:58:37 EDT //www.koonmotors.com/releases/2023/07/230717115837.htm //www.koonmotors.com/releases/2023/07/230713141945.htm Study suggests modulating the activity of certain neurons could be an effective approach to restoring circuit function. Thu, 13 Jul 2023 14:19:45 EDT //www.koonmotors.com/releases/2023/07/230713141945.htm //www.koonmotors.com/releases/2023/07/230712124740.htm An overdosed gene on chromosome 21 causes people with Down's Syndrome to age faster than the general population. Wed, 12 Jul 2023 12:47:40 EDT //www.koonmotors.com/releases/2023/07/230712124740.htm //www.koonmotors.com/releases/2023/07/230711133106.htm Fetuses use a copy of a gene inherited from their dad to force their mum to release as much nutrients as possible during pregnancy, scientists have discovered. The unborn baby 'remote controls' its mother's metabolism so the two are in a nutritional tug of war. The mother's body wants the baby to survive but needs to keep enough glucose and fats circulating in her system for her own health, to be able to deliver the baby, breastfeed and to reproduce again. Tue, 11 Jul 2023 13:31:06 EDT //www.koonmotors.com/releases/2023/07/230711133106.htm //www.koonmotors.com/releases/2023/07/230707111622.htm The mucus in the airways is not as sticky, inflammation in the lungs significantly reduced: Triple combination therapy can achieve these positive, lasting effects in patients with cystic fibrosis (CF). According to new research, this form of medication improves the symptoms of CF in many patients. Fri, 07 Jul 2023 11:16:22 EDT //www.koonmotors.com/releases/2023/07/230707111622.htm //www.koonmotors.com/releases/2023/07/230706160116.htm Researchers showed that consuming THC while pregnant could potentially affect development of the fetus and lead to life-long health impacts for offspring. Thu, 06 Jul 2023 16:01:16 EDT //www.koonmotors.com/releases/2023/07/230706160116.htm //www.koonmotors.com/releases/2023/07/230706124520.htm As a psychiatric disorder with onset in adulthood, schizophrenia is thought to be triggered by some combination of environmental factors and genetics, although the exact cause is still not fully understood. Researchers have now found a correlation between schizophrenia and somatic copy-number variants, a type of mutation that occurs early in development but after genetic material is inherited. This study is one of the first to rigorously describe the relationship between somatic -- not inherited -- genetic mutations and schizophrenia risk. Thu, 06 Jul 2023 12:45:20 EDT //www.koonmotors.com/releases/2023/07/230706124520.htm //www.koonmotors.com/releases/2023/07/230705194525.htm In a world-first, 3D holographic images of an embryo have been developed. The images are created using minuscule amounts of light in a fraction of a second. Wed, 05 Jul 2023 19:45:25 EDT //www.koonmotors.com/releases/2023/07/230705194525.htm //www.koonmotors.com/releases/2023/07/230705143010.htm An antisense therapy restores production of the protein FMRP in cell samples taken from patients with fragile X syndrome. This breakthrough was possible because of the novel findings, also presented in the study, that aberrant alternative splicing of messenger RNA (mRNA) plays a principal role in fragile X syndrome, the most common form of inherited intellectual disability and the most frequent single-gene cause of autism. Wed, 05 Jul 2023 14:30:10 EDT //www.koonmotors.com/releases/2023/07/230705143010.htm //www.koonmotors.com/releases/2023/07/230703133055.htm Adenosine base editing restarted fetal hemoglobin expression in cells from patients with sickle cell disease. Mon, 03 Jul 2023 13:30:55 EDT //www.koonmotors.com/releases/2023/07/230703133055.htm //www.koonmotors.com/releases/2023/06/230627123010.htm Scientists have created a stem cell-derived model of the human embryo in the lab by reprogramming human stem cells. The breakthrough could help research into genetic disorders and in understanding why and how pregnancies fail. Tue, 27 Jun 2023 12:30:10 EDT //www.koonmotors.com/releases/2023/06/230627123010.htm //www.koonmotors.com/releases/2023/06/230620174504.htm Scientists have written a review to discuss emerging research and evidence of the roles of alternative splicing defects in major neurodegenerative diseases. They also summarize the latest advances in RNA-based therapeutic strategies to target these disorders. Tue, 20 Jun 2023 17:45:04 EDT //www.koonmotors.com/releases/2023/06/230620174504.htm //www.koonmotors.com/releases/2023/06/230606111503.htm Researchers have shown that defective myelin actively promotes disease-related changes in Alzheimer's disease. Tue, 06 Jun 2023 11:15:03 EDT //www.koonmotors.com/releases/2023/06/230606111503.htm //www.koonmotors.com/releases/2023/05/230531150122.htm Researchers have partnered to create a first-of-its-kind open-source, reproducible analysis platform for pediatric brain tumors. With the help of thousands of genomically sequenced samples, researchers have used this platform to identify initial findings about genetic variants associated with poorer outcomes that could help guide future diagnostic and therapeutic advances. Wed, 31 May 2023 15:01:22 EDT //www.koonmotors.com/releases/2023/05/230531150122.htm //www.koonmotors.com/releases/2023/05/230530125442.htm The early stages of embryonic development contain many of life's mysteries. Unlocking these mysteries can help us better understand early development and birth defects, and help develop new regenerative medicine treatments. Researchers have now characterized a critical time in mammalian embryonic development using powerful and innovative imaging techniques. Tue, 30 May 2023 12:54:42 EDT //www.koonmotors.com/releases/2023/05/230530125442.htm //www.koonmotors.com/releases/2023/05/230511164625.htm Called the human connectome, this structural system of neural pathways develops as people age. A new study shows transmission speed among brain regions increases into early adulthood. Learning more about neuron transmission may improve the understanding of psychological disorders. Thu, 11 May 2023 16:46:25 EDT //www.koonmotors.com/releases/2023/05/230511164625.htm //www.koonmotors.com/releases/2023/05/230505101659.htm Scientists have found a lipid transporter crucial to regulating the cells that make myelin, the nerve-protecting sheath. Fri, 05 May 2023 10:16:59 EDT //www.koonmotors.com/releases/2023/05/230505101659.htm //www.koonmotors.com/releases/2023/05/230504094946.htm Goldenhar syndrome is a rare congenital disease, affecting early fetal development. This syndrome includes malformations of varying severity, affecting different parts of the face. Its causes and modes of transmission are still poorly understood. An international collaboration has discovered that pathogenic variants of the FOXI3 gene -- responsible for the development of the ear -- cause one form of this developmental disorder. The scientists were also able to identify the modes of transmission of the disease when this particular gene is involved. Thu, 04 May 2023 09:49:46 EDT //www.koonmotors.com/releases/2023/05/230504094946.htm //www.koonmotors.com/releases/2023/04/230424133602.htm 问题“修剪”itsel大脑的能力f of unnecessary connections may underlie a wide range of mental health disorders that begin during adolescence, according to research published today. The findings may help explain why people are often affected by more than one mental health disorder, and may in future help identify those at greatest risk. Mon, 24 Apr 2023 13:36:02 EDT //www.koonmotors.com/releases/2023/04/230424133602.htm //www.koonmotors.com/releases/2023/04/230421195030.htm A team showed how both alcohol intake and alcohol withdrawal can lead to increased pain and hypersensitivity. Fri, 21 Apr 2023 19:50:30 EDT //www.koonmotors.com/releases/2023/04/230421195030.htm //www.koonmotors.com/releases/2023/04/230420141754.htm Researchers have found that an extra copy of a gene in Down syndrome patients causes improper development of neurons in mice. Thu, 20 Apr 2023 14:17:54 EDT //www.koonmotors.com/releases/2023/04/230420141754.htm //www.koonmotors.com/releases/2023/04/230420110138.htm New research examines the impact that maternal stress during pregnancy has on the neuro-development of babies. Thu, 20 Apr 2023 11:01:38 EDT //www.koonmotors.com/releases/2023/04/230420110138.htm //www.koonmotors.com/releases/2023/04/230419201925.htm What are the consequences of mothers consuming alcohol while breastfeeding? A research team at the University of California, Riverside, performed a mouse study to find out. Wed, 19 Apr 2023 20:19:25 EDT //www.koonmotors.com/releases/2023/04/230419201925.htm //www.koonmotors.com/releases/2023/04/230418101427.htm Information available at birth may help to identify children with higher likelihood of developing ADHD, according to new research. Tue, 18 Apr 2023 10:14:27 EDT //www.koonmotors.com/releases/2023/04/230418101427.htm //www.koonmotors.com/releases/2023/04/230412153138.htm Research investigating fetal alcohol syndrome (FAS) exclusively examines maternal alcohol exposure. However, because men drink more and are more likely to binge drink than women, scientists set out to challenge the existing dogma, using a mouse model to examine what happens when the mother, father and both parents consume alcohol. Wed, 12 Apr 2023 15:31:38 EDT //www.koonmotors.com/releases/2023/04/230412153138.htm //www.koonmotors.com/releases/2023/04/230404114235.htm A team has induced stem cells to emulate the development of the human heart. The result is a sort of 'mini-heart' known as an organoid. It will permit the study of the earliest development phase of our heart and facilitate research on diseases. Tue, 04 Apr 2023 11:42:35 EDT //www.koonmotors.com/releases/2023/04/230404114235.htm //www.koonmotors.com/releases/2023/03/230330102230.htm In an analysis of over 65,000 infants from Japan, children exposed to pet cats or indoor dogs during fetal development or early infancy tended to have fewer food allergies compared to other children. Thu, 30 Mar 2023 10:22:30 EDT //www.koonmotors.com/releases/2023/03/230330102230.htm //www.koonmotors.com/releases/2023/03/230321112559.htm New clinical guidance has been developed to help physicians and patients identify if unexplained digestive symptoms are due to alpha-gal syndrome, a food allergy that is caused by lone star tick bites. Tue, 21 Mar 2023 11:25:59 EDT //www.koonmotors.com/releases/2023/03/230321112559.htm //www.koonmotors.com/releases/2023/03/230316124440.htm Criteria used by neurologists to assess for multiple sclerosis (MS) in adults may fail to identify the illness in children with imaging suspicious for the disease, an oversight that could delay treatment of the disease at its earliest stages, according to a new study. Thu, 16 Mar 2023 12:44:40 EDT //www.koonmotors.com/releases/2023/03/230316124440.htm //www.koonmotors.com/releases/2023/03/230314155049.htm 研究人员已经发现了一个新奇的监管工作anism in the brain that is essential for making the right kinds of proteins that promote healthy brain function, and its malfunctioning may be an early contributor of the development of Alzheimer's disease. Tue, 14 Mar 2023 15:50:49 EDT //www.koonmotors.com/releases/2023/03/230314155049.htm //www.koonmotors.com/releases/2023/03/230308112221.htm Researchers have learned that the same molecular pathway is involved in both the infectious and hemorrhagic forms of acquired hydrocephalus, a life-threatening disease that triggers a massive neuroinflammatory response and swelling of the ventricles of the brain. Wed, 08 Mar 2023 11:22:21 EST //www.koonmotors.com/releases/2023/03/230308112221.htm //www.koonmotors.com/releases/2023/03/230307073201.htm A commonly used scientific method to analyze a tiny amount of DNA in early human embryos fails to accurately reflect gene edits, according to new research. Although gene editing technologies hold promise in preventing and treating debilitating inherited diseases, the new study reveals limitations that must be overcome before gene-editing to establish a pregnancy can be deemed safe or effective. Tue, 07 Mar 2023 07:32:01 EST //www.koonmotors.com/releases/2023/03/230307073201.htm //www.koonmotors.com/releases/2023/03/230306143339.htm Researchers assessed in an animal model the effect of folic acid supplementation on mutation rates and other genetic modifications. Mon, 06 Mar 2023 14:33:39 EST //www.koonmotors.com/releases/2023/03/230306143339.htm //www.koonmotors.com/releases/2023/03/230303105350.htm The immune system of pregnant women with anxiety is biologically different from that of pregnant women without anxiety, according to new research. Fri, 03 Mar 2023 10:53:50 EST //www.koonmotors.com/releases/2023/03/230303105350.htm //www.koonmotors.com/releases/2023/02/230227132657.htm New research has uncovered a novel link between the Duchenne muscular dystrophy (DMD) gene and cancer. Mon, 27 Feb 2023 13:26:57 EST //www.koonmotors.com/releases/2023/02/230227132657.htm //www.koonmotors.com/releases/2023/02/230224135044.htm Adverse childhood experiences in mothers can affect their children's mental and physical health, as researchers report. The study found that maltreatment during a mother's childhood is associated with a higher risk of health problems such as asthma, autism, and depression in the next generation. Early intervention to support affected mothers might help to counter this effect. Fri, 24 Feb 2023 13:50:44 EST //www.koonmotors.com/releases/2023/02/230224135044.htm //www.koonmotors.com/releases/2023/02/230222111747.htm Physicians have discovered why the immune system of prematurely born babies is not working optimally after birth. Wed, 22 Feb 2023 11:17:47 EST //www.koonmotors.com/releases/2023/02/230222111747.htm //www.koonmotors.com/releases/2023/02/230221113055.htm During the fetal stage, a number of so-called cell programs run that are vital to the development of the fetus. Researchers demonstrate that one of these fetal programs appears to protect against acute myeloid leukaemia (AML). Tue, 21 Feb 2023 11:30:55 EST //www.koonmotors.com/releases/2023/02/230221113055.htm //www.koonmotors.com/releases/2023/02/230216083947.htm 研究人员利用人工智能d爱博网投官方网站iscover a link between alterations in the shape of children's faces and the amount of alcohol their mothers drank, before and during pregnancy. Even small amounts, less than one glass of wine a week, made a difference. Face shapes are an indicator of underlying health and developmental problems. Thu, 16 Feb 2023 08:39:47 EST //www.koonmotors.com/releases/2023/02/230216083947.htm //www.koonmotors.com/releases/2023/02/230216083406.htm In Fragile X syndrome, sensory signals from the outside world are integrated differently, causing them to be underrepresented by cortical pyramidal neurons in the brain, according to a new study. Thu, 16 Feb 2023 08:34:06 EST //www.koonmotors.com/releases/2023/02/230216083406.htm //www.koonmotors.com/releases/2023/02/230215143326.htm Multiple births, a short interval between pregnancies and mothers with a maternal physical or mental health condition are more at risk of having a low birth rate baby. Every year 20 million children are born with a birth weight below 2,500 grams, and considered low birthweight (LBW) babies The study looked to understand the risk factors for LBW so that resources and interventions could be scheduled effectively. Wed, 15 Feb 2023 14:33:26 EST //www.koonmotors.com/releases/2023/02/230215143326.htm //www.koonmotors.com/releases/2023/02/230213201102.htm 行为障碍是孤独症患者中一样sociated with a multitude of genetic alterations. Scientists have now found another molecular cause for this condition. The transcription factor MYT1L normally protects the molecular identity of nerve cells. If it is genetically switched off in human nerve cells or in mice, the functional changes and symptoms typical of autism occur. A drug that blocks sodium channels in the cell membrane can reverse the consequences of MYT1L failure and alleviate the functional and behavioral abnormalities in mice. Mon, 13 Feb 2023 20:11:02 EST //www.koonmotors.com/releases/2023/02/230213201102.htm //www.koonmotors.com/releases/2023/02/230209141512.htm Researchers have discovered, in rodents, that fluid that circulates through the brain flows to areas critical for normal brain development and function, suggesting that disruptions to its circulation may play an under-recognized role in neurodevelopmental disorders. Thu, 09 Feb 2023 14:15:12 EST //www.koonmotors.com/releases/2023/02/230209141512.htm //www.koonmotors.com/releases/2023/02/230201134231.htm Recent advances in newborn heart surgery have greatly reduced brain injuries in infants with congenital heart disease, according to a 20-year study. Wed, 01 Feb 2023 13:42:31 EST //www.koonmotors.com/releases/2023/02/230201134231.htm //www.koonmotors.com/releases/2023/01/230124192559.htm Researchers present the first evidence of 12-hour cycles of gene activity in the human brain. The study also reveals that some of those 12-hour rhythms are missing or altered in the postmortem brains of patients with schizophrenia. Tue, 24 Jan 2023 19:25:59 EST //www.koonmotors.com/releases/2023/01/230124192559.htm //www.koonmotors.com/releases/2023/01/230124132014.htm A new study suggests that some patients diagnosed with behavioral-variant frontotemporal dementia (bvFTD) -- an incurable condition that robs patients of the ability to control their behavior and cope with daily living -- may instead have a cerebrospinal fluid leak, which is often treatable. Tue, 24 Jan 2023 13:20:14 EST //www.koonmotors.com/releases/2023/01/230124132014.htm //www.koonmotors.com/releases/2023/01/230124112733.htm A new study assessed the associations between maternal exposure to green and blue spaces during pregnancy and birth outcomes in 11 birth cohorts from nine European countries, including Spain. The results of the study indicate that proximity to residential green space is associated with higher birth weight and lower odds of having a small-for-gestational-age baby. Tue, 24 Jan 2023 11:27:33 EST //www.koonmotors.com/releases/2023/01/230124112733.htm